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Jan Gratama

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Co-Publications
Name
31
Kraan, Jaco
14
Lamers, Cor
14
Bolhuis, Reinder
14
Sleijfer, Stefan
13
Levering, Wilfried
13
Debets, Reno
12
Cornelissen, Jan
11
Sintnicolaas, Kees
11
van der Holt, Bronno
10
Keeney, Michael
9
Hooijkaas, Herbert
8
Löwenberg, Bob
7
de Beukelaar, Janet
7
Barnett, David
7
van Esser, Joost

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Publications

TOP 3
Mandy Frank; Gratama Jan W
Flow cytometry: a biomedical platform offering diagnostic diversity.
Hulspas Ruud; O'Gorman Maurice R G; Wood Brent L; Gratama Jan W; Sutherland D Robert
Considerations for the control of background fluorescence in clinical flow cytometry.
Strijbos Michiel H; Verhoef Cornelis; Gratama Jan W; Sleijfer Stefan
On the origin of (CD105+) circulating endothelial cells.

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All Publications

2009: Mandy Frank; Gratama Jan W
Flow cytometry: a biomedical platform offering diagnostic diversity.
Cytometry. Part B, Clinical cytometry 2009;76(6):365-6.
2009: Hulspas Ruud; O'Gorman Maurice R G; Wood Brent L; Gratama Jan W; Sutherland D Robert
Considerations for the control of background fluorescence in clinical flow cytometry.
Cytometry. Part B, Clinical cytometry 2009;76(6):355-64.
2009: Strijbos Michiel H; Verhoef Cornelis; Gratama Jan W; Sleijfer Stefan
On the origin of (CD105+) circulating endothelial cells.
Thrombosis and haemostasis 2009;102(2):347-51.
2009: Strijbos Michiel H; Landburg Precious P; Nur Erfan; Teerlink Tom; Leebeek Frank W G; Rijneveld Anita W; Biemond Bart J; Sleijfer Stefan; Gratama Jan W; Duits Ashley J; Schnog John-John B;
Circulating endothelial cells: a potential parameter of organ damage in sickle cell anemia?
Blood cells, molecules & diseases 2009;43(1):63-7.
2009: Strijbos Michiel H; Kraan Jaco; Lamers Cor H J; Sleijfer Stefan; Gratama Jan W
Quantification of circulating endothelial cells by flow cytometry.
Clinical cancer research : an official journal of the American Association for Cancer Research 2009;15(10):3640; author reply 3640-1.
2009: de Beukelaar Janet W; Milikan Johannes C; Verjans Georges M; de Graaf Marieke T; van Norden Yvette; Lamers Cor H; van den Bent Martin J; Bromberg Jacoline E; Hulsenboom Esther; Sintnicolaas Kees; Gratama Jan W; Sillevis Smitt Peter A
No evidence for the presence of HuD-specific T cells in the cerebrospinal fluid of patients with Hu-associated paraneoplastic neurological syndromes.
Journal of neurology 2009;256(2):279-82.
2008: Gratama Jan W; Kern Florian; Manca Fabrizio; Roederer Mario
Measuring antigen-specific immune responses, 2008 update.
Cytometry. Part A : the journal of the International Society for Analytical Cytology 2008;73(11):971-4.
2008: Brooimans Rik A; Boyce Christopher S; Popma Janice; Broyles Dennis A; Gratama Jan W; Southwick Paula C; Keeney Michael
Analytical performance of a standardized single-platform MHC tetramer assay for the identification and enumeration of CMV-specific CD8+ T lymphocytes.
Cytometry. Part A : the journal of the International Society for Analytical Cytology 2008;73(11):992-1000.
2008: Willemsen Ralph; Chames Patrick; Schooten Erik; Gratama Jan Willem; Debets Reno
Selection of human antibody fragments directed against tumor T-cell epitopes for adoptive T-cell therapy.
Cytometry. Part A : the journal of the International Society for Analytical Cytology 2008;73(11):1093-9.
2008: de Graaf Marieke T; de Beukelaar Janet W; Burgers Peter C; Luider Theo M; Kraan Jaco; Smitt Peter A Sillevis; Gratama Jan W
Contamination of synthetic HuD protein spanning peptide pools with a CMV-encoded peptide.
Cytometry. Part A : the journal of the International Society for Analytical Cytology 2008;73(11):1079-85.
2008: Strijbos Michiel H; Rao Chandra; Schmitz Paul I M; Kraan Jaco; Lamers Cor H; Sleijfer Stefan; Terstappen Leon W M M; Gratama Jan W
Correlation between circulating endothelial cell counts and plasma thrombomodulin levels as markers for endothelial damage.
Thrombosis and haemostasis 2008;100(4):642-7.
2008: Kirchner Alexander; Hoffmeister Bodo; Cherepnev-G Georgy; Fuhrmann Stephan; Streitz Mathias; Lachmann Raskit; Bunde Torsten; Meij Pauline; Schönemann Constanze; Hetzer Roland; Lehmkuhl Hans B; Volkmer-Engert Rudolf; Volk Hans-Dieter; Gratama Jan W; Kern Florian
Dissection of the CMV specific T-cell response is required for optimized cardiac transplant monitoring.
Journal of medical virology 2008;80(9):1604-14.
2008: Porcelijn Leendert; van Beers Wil; Gratama Jan W; van't Veer Mars; De Smet Annie; Sintnicolaas Kees
External quality assessment of platelet serology and human platelet antigen genotyping: a 10-year review.
Transfusion 2008;48(8):1699-706.
2008: Kraan Jaco; Gratama Jan W; Haioun Corinne; Orfao Alberto; Plonquet Anne; Porwit Anna; Quijano Sandra; Stetler-Stevenson Maryalice; Subira Dolores; Wilson Wyndham
Flow cytometric immunophenotyping of cerebrospinal fluid.
Current protocols in cytometry / editorial board, J. Paul Robinson, managing editor ... [et al.] 2008;Chapter 6():Unit 6.25.
2008: Gratama Jan W; Brooimans Rik A; van der Holt Bronno; Sintnicolaas Kees; van Doornum Gerard; Niesters Hubertus G; Löwenberg Bob; Cornelissen Jan J
Monitoring cytomegalovirus IE-1 and pp65-specific CD4+ and CD8+ T-cell responses after allogeneic stem cell transplantation may identify patients at risk for recurrent CMV reactivations.
Cytometry. Part B, Clinical cytometry 2008;74(4):211-20.
2008: Strijbos M H; Gratama J W; Kraan J; Lamers C H; den Bakker M A; Sleijfer S
Circulating endothelial cells in oncology: pitfalls and promises.
British journal of cancer 2008;98(11):1731-5.
2008: Sebestyén Zsolt; Schooten Erik; Sals Tamara; Zaldivar Irene; San José Esther; Alarcón Balbino; Bobisse Sara; Rosato Antonio; Szöllosi János; Gratama Jan Willem; Willemsen Ralph A; Debets Reno
Human TCR that incorporate CD3zeta induce highly preferred pairing between TCRalpha and beta chains following gene transfer.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(11):7736-46.
2008: Levering Wilfried H B M; Wind Henk; Granger Vivian; Sintnicolaas Kees; Hooijkaas Herbert; Reilly John T; Gratama Jan W; Barnett David
Long-term stabilized blood samples as controls for flow cytometric HLA-B27 screening: a feasibility study.
Cytometry. Part B, Clinical cytometry 2008;74(3):169-81.
2008: Lamers C H J; van Elzakker P; Luider B A; van Steenbergen S C L; Sleijfer S; Debets R; Gratama J W
Retroviral vectors for clinical immunogene therapy are stable for up to 9 years.
Cancer gene therapy 2008;15(4):268-74.
2008: de Graaf Marieke; de Beukelaar Janet; Bergsma Jelmer; Kraan Jaco; van den Bent Martin; Klimek Markus; van Norden Yvette; Kusuma Arinardi; Smitt Peter Sillevis; Gratama Jan Willem
B and T cell imbalances in CSF of patients with Hu-antibody associated PNS.
Journal of neuroimmunology 2008;195(1-2):164-70.
2008: Levering Wilfried H B M; van Wieringen Wessel N; Kraan Jaco; van Beers Wil A M; Sintnicolaas Kees; van Rhenen Dick J; Gratama Jan W
Flow cytometric lymphocyte subset enumeration: 10 years of external quality assessment in the Benelux countries.
Cytometry. Part B, Clinical cytometry 2008;74(2):79-90.
2008: Lamers C H J; van Elzakker P; van Steenbergen S C L; Sleijfer S; Debets R; Gratama J W
Retronectin-assisted retroviral transduction of primary human T lymphocytes under good manufacturing practice conditions: tissue culture bag critically determines cell yield.
Cytotherapy 2008;10(4):406-16.
2007: de Beukelaar J W; Sillevis Smitt P A; Hop W C; Kraan J; Hooijkaas H; Verjans G M G M; Gratama J W
Imbalances in circulating lymphocyte subsets in Hu antibody associated paraneoplastic neurological syndromes.
European journal of neurology : the official journal of the European Federation of Neurological Societies 2007;14(12):1383-91.
2007: Sleijfer Stefan; Gratama Jan-Willem; Sieuwerts Anieta M; Kraan Jaco; Martens John W M; Foekens John A
Circulating tumour cell detection on its way to routine diagnostic implementation?
European journal of cancer (Oxford, England : 1990) 2007;43(18):2645-50.
2007: Lamers Cor H J; Langeveld Sabine C L; Groot-van Ruijven Corrien M; Debets Reno; Sleijfer Stefan; Gratama Jan Willem
Gene-modified T cells for adoptive immunotherapy of renal cell cancer maintain transgene-specific immune functions in vivo.
Cancer immunology, immunotherapy : CII 2007;56(12):1875-83.
2007: Strijbos Michiel H; Kraan Jaco; Sleijfer Stefan; Gratama Jan W
Potential biomarkers in metastatic gastrointestinal stromal tumors.
Clinical cancer research : an official journal of the American Association for Cancer Research 2007;13(20):6244.
2007: de Beukelaar Janet W; Verjans Georges M; van Norden Yvette; Milikan Johannes C; Kraan Jaco; Hooijkaas Herbert; Sintnicolaas Kees; Gratama Jan W; Sillevis Smitt Peter A
No evidence for circulating HuD-specific CD8+ T cells in patients with paraneoplastic neurological syndromes and Hu antibodies.
Cancer immunology, immunotherapy : CII 2007;56(9):1501-6.
2007: Ratei R; Karawajew L; Lacombe F; Jagoda K; Del Poeta G; Kraan J; De Santiago M; Kappelmayer J; Björklund E; Ludwig W-D; Gratama J W; Orfao A;
Discriminant function analysis as decision support system for the diagnosis of acute leukemia with a minimal four color screening panel and multiparameter flow cytometry immunophenotyping.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2007;21(6):1204-11.
2007: Bromberg J E C; Breems D A; Kraan J; Bikker G; van der Holt B; Smitt P Sillevis; van den Bent M J; van't Veer M; Gratama J W
CSF flow cytometry greatly improves diagnostic accuracy in CNS hematologic malignancies.
Neurology 2007;68(20):1674-9.
2007: Levering Wilfried H B M; Preijers Frank W M B; van Wieringen Wessel N; Kraan Jaco; van Beers Wil A M; Sintnicolaas Kees; van Rhenen Dick J; Gratama Jan W
Flow cytometric CD34+ stem cell enumeration: lessons from nine years' external quality assessment within the Benelux countries.
Cytometry. Part B, Clinical cytometry 2007;72(3):178-88.
2007: Li Pira Giuseppina; Kern Florian; Gratama Jan; Roederer Mario; Manca Fabrizio
Measurement of antigen specific immune responses: 2006 update.
Cytometry. Part B, Clinical cytometry 2007;72(2):77-85.
2007: Strijbos Michiel H; Kraan Jaco; den Bakker Michael A; Lambrecht Bart N; Sleijfer Stefan; Gratama Jan W
Cells meeting our immunophenotypic criteria of endothelial cells are large platelets.
Cytometry. Part B, Clinical cytometry 2007;72(2):86-93.
2007: Brando Bruno; Gatti Arianna; Chianese Rosa; Gratama Jan Willem
Twenty years of external quality assurance in clinical cell analysis--a tribute to Jean-Luc D'Hautcourt.
Cytometry. Part B, Clinical cytometry 2007;72(1):2-7.
2007: de Beukelaar Janet W; Gratama Jan W; Smitt Peter A Sillevis; Verjans Georges M; Kraan Jaco; Luider Theo M; Burgers Peter C
The impact of impurities in synthetic peptides on the outcome of T-cell stimulation assays.
Rapid communications in mass spectrometry : RCM 2007;21(7):1282-8.
2006: Lamers Cor H J; Sleijfer Stefan; Vulto Arnold G; Kruit Wim H J; Kliffen Mike; Debets Reno; Gratama Jan W; Stoter Gerrit; Oosterwijk Egbert
Treatment of metastatic renal cell carcinoma with autologous T-lymphocytes genetically retargeted against carbonic anhydrase IX: first clinical experience.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2006;24(13):e20-2.
2006: Boonstra Joke G; van Lom Kirsten; Langerak Anton W; Graveland Wilfried J; Valk Peter J M; Kraan Jaco; van 't Veer Mars B; Gratama Jan W
CD38 as a prognostic factor in B cell chronic lymphocytic leukaemia (B-CLL): comparison of three approaches to analyze its expression.
Cytometry. Part B, Clinical cytometry 2006;70(3):136-41.
2006: Lamers C H J; Willemsen R A; van Elzakker P; van Krimpen B A; Gratama J W; Debets R
Phoenix-ampho outperforms PG13 as retroviral packaging cells to transduce human T cells with tumor-specific receptors: implications for clinical immunogene therapy of cancer.
Cancer gene therapy 2006;13(5):503-9.
2006: Te Boekhorst P A W; Lamers C H J; Schipperus M R; Hintzen R Q; van der Holt B; Cornelissen J J; Löwenberg B; Gratama J W
T-lymphocyte reconstitution following rigorously T-cell-depleted versus unmodified autologous stem cell transplants.
Bone marrow transplantation 2006;37(8):763-72.
2006: Schaft Niels; Lankiewicz Birgit; Drexhage Joost; Berrevoets Cor; Moss Denis J; Levitsky Victor; Bonneville Marc; Lee Steven P; McMichael Andrew J; Gratama Jan-Willem; Bolhuis Reinier L H; Willemsen Ralph; Debets Reno
T cell re-targeting to EBV antigens following TCR gene transfer: CD28-containing receptors mediate enhanced antigen-specific IFNgamma production.
International immunology 2006;18(4):591-601.
2006: Shams'ili Setareh; de Beukelaar Janet; Gratama Jan Willem; Hooijkaas Herbert; van den Bent Martin; van 't Veer Mars; Sillevis Smitt Peter
An uncontrolled trial of rituximab for antibody associated paraneoplastic neurological syndromes.
Journal of neurology 2006;253(1):16-20.
2006: Ratei Richard; Karawajew Leonid; Lacombe Francis; Jagoda Krystyna; Del Poeta Giovanni; Kraan Jaco; De Santiago Maria; Kappelmayer János; Björklund Elisabeth; Ludwig W-D; Gratama Jan; Orfao Alberto;
Normal lymphocytes from leukemic samples as an internal quality control for fluorescence intensity in immunophenotyping of acute leukemias.
Cytometry. Part B, Clinical cytometry 2006;70(1):1-9.
2006: Lamers C H J; van Elzakker P; Langeveld S C L; Sleijfer S; Gratama J W
Process validation and clinical evaluation of a protocol to generate gene-modified T lymphocytes for imunogene therapy for metastatic renal cell carcinoma: GMP-controlled transduction and expansion of patient's T lymphocytes using a carboxy anhydrase IX-specific scFv transgene.
Cytotherapy 2006;8(6):542-53.
2006: Gratama Jw; Kvalheim G; Orfao A
Standardization of cell analysis methods in clinical cellular therapy programs: A challenge for ISCT.
Cytotherapy 2006;8(6):528-9.
2005: Lamers C H J; Gratama J W; Pouw N M C; Langeveld S C L; Krimpen B A Van; Kraan J; Stoter G; Debets R
Parallel detection of transduced T lymphocytes after immunogene therapy of renal cell cancer by flow cytometry and real-time polymerase chain reaction: implications for loss of transgene expression.
Human gene therapy 2005;16(12):1452-62.
2005: de Beukelaar Janet W; van Arkel Cornelis; van den Bent Martin J; van't Veer Mars B; van Doornum Gerard J; Cornelissen Jan J; Sillevis Smitt Peter A; Gratama Jan W
Resolution of EBV(+) CNS lymphoma with appearance of CSF EBV-specific T cells.
Annals of neurology 2005;58(5):788-92.
2005: Kern Florian; LiPira Giuseppina; Gratama Jan W; Manca Fabrizio; Roederer Mario
Measuring Ag-specific immune responses: understanding immunopathogenesis and improving diagnostics in infectious disease, autoimmunity and cancer.
Trends in immunology 2005;26(9):477-84.
2005: Levering Wilfried H B M; Sintnicolaas Kees; Wind Henk; Hooijkaas Herbert; Gratama Jan W
Flow cytometric screening for the HLA-B27 antigen on peripheral blood lymphocytes.
Current protocols in cytometry / editorial board, J. Paul Robinson, managing editor ... [et al.] 2005;Chapter 6():Unit6.22.
2005: Broers Annoek E C; van der Holt Bronno; Haze Sebastiaan; Braakman Eric; Gratama Jan-Willem; Löwenberg Bob; Cornelissen Jan J
A comparison of postengraftment infectious morbidity and mortality after allogeneic partially T cell-depleted peripheral blood progenitor cell transplantation versus T cell-depleted bone marrow transplantation.
Experimental hematology 2005;33(8):912-9.
2005: Brooimans R A; de Leeuw N; Bontenbal M; Gratama J W
An immunomagnetic epithelial tumor cell enrichment model for minimal residual disease detection of cytokeratin 8+ malignancies.
Journal of biological regulators and homeostatic agents 2005;19(1-2):84-91.
2005: Portielje Johanna E A; Kruit Wim H J; Eerenberg Anke J M; Schuler Martin; Sparreboom Alex; Lamers Cor H J; Gratama Jan-Willem; Stoter Gerrit; Huber Christoph; Hack C Erik
Subcutaneous injection of interleukin 12 induces systemic inflammatory responses in humans: implications for the use of IL-12 as vaccine adjuvant.
Cancer immunology, immunotherapy : CII 2005;54(1):37-43.
2004: Levin M-D; van der Holt B; de Veld J C; Gratama J W; de Vries W; van't Veer M B
The value of crossmatch tests and panel tests as a screening tool to predict the outcome of platelet transfusion in a non-selected haematological population of patients.
Vox sanguinis 2004;87(4):291-8.
2004: Heijnen Ingmar A F M; Barnett David; Arroz Maria J; Barry Simon M; Bonneville Marc; Brando Bruno; D'hautcourt Jean-Luc; Kern Florian; Tötterman Thomas H; Marijt Erik W A; Bossy David; Preijers Frank W M B; Rothe Gregor; Gratama Jan W;
Enumeration of antigen-specific CD8+ T lymphocytes by single-platform, HLA tetramer-based flow cytometry: a European multicenter evaluation.
Cytometry. Part B, Clinical cytometry 2004;62(1):1-13.
2004: Pérez-Andrés M; Santiago M; Almeida J; Mateo G; Porwit-MacDonald A; Bjorklund E; Valet G; Kraan J; Gratama J W; D'Hautcourt J L; Merle-Beral H; Lima M; Montalban M A; San Miguel J F; Orfao I;
Immunophenotypic approach to the identification and characterization of clonal plasma cells from patients with monoclonal gammopathies.
Journal of biological regulators and homeostatic agents 2004;18(3-4):392-8.
2004: Boonstra J G; von't Veer M B; Gratama J W
The use of CD38 expression by monoclonal B lymphocytes as a prognostic factor in B-cell chronic lymphocytic leukemia.
Journal of biological regulators and homeostatic agents 2004;18(3-4):340-6.
2004: van Wering E R; van Lochem E G; Leenders M; van der Sluijs-Gelling A J; Wind H; Gratama J W; Kraan J; Preijers F W M B
Three-color flowcytometric analysis of mature and immature hematological malignancies. A guideline of the Dutch Foundation for Immunophenotyping of Hematological Malignancies (SIHON).
Journal of biological regulators and homeostatic agents 2004;18(3-4):313-26.
2004: Lamers C H J; Sleijfer S; Willemsen R A; Debets R; Kruit W H J; Gratama J W; Stoter G
Adoptive immuno-gene therapy of cancer with single chain antibody [scFv(Ig)] gene modified T lymphocytes.
Journal of biological regulators and homeostatic agents 2004;18(2):134-40.
2004: Gratama J W; Kern F
Flow cytometric enumeration of antigen-specific T lymphocytes.
Cytometry. Part A : the journal of the International Society for Analytical Cytology 2004;58(1):79-86.
2004: Keeney Michael; Gratama Jan W; Sutherland D Robert
Critical role of flow cytometry in evaluating peripheral blood hematopoietic stem cell grafts.
Cytometry. Part A : the journal of the International Society for Analytical Cytology 2004;58(1):72-5.
2004: Levin M-D; van der Holt B; de Veld J C; Gratama J W; de Vries W; van't Veer M B
Visual scoring versus histogram subtraction of in vivo binding of immunoglobulins against platelets after transfusion.
Cytometry. Part B, Clinical cytometry 2004;57(1):40-6.
2003: Schaft Niels; Lankiewicz Birgit; Gratama Jan Willem; Bolhuis Reinder L H; Debets Reno
Flexible and sensitive method to functionally validate tumor-specific receptors via activation of NFAT.
Journal of immunological methods 2003;280(1-2):13-24.
2003: Sutherland D Robert; Keeney Michael; Gratama Jan W
Enumeration of CD34+ hematopoietic stem and progenitor cells.
Current protocols in cytometry / editorial board, J. Paul Robinson, managing editor ... [et al.] 2003;Chapter 6():Unit 6.4.
2003: Kraan J; Arroz M; Keeney M; Freire M; Weir K; Heijnen I; Gratama J W;
Flow cytometric enumeration of Class I HLA-restricted, peptide-specific CD8+ T lymphocytes using tetramer technology and single-platform absolute T-cell counting.
Journal of biological regulators and homeostatic agents 2003;17(3):268-78.
2003: Levering W H B M; Wind H; Hooijkaas H; Sintnicolaas K; Brando B; Gratama J W
Flow cytometric screening for HLA-B27 on peripheral blood lymphocytes.
Journal of biological regulators and homeostatic agents 2003;17(3):241-6.
2003: Kraan J; Gratama J W; Keeney M; D'Hautcourt J L
Setting up and calibration of a flow cytometer for multicolor immunophenotyping.
Journal of biological regulators and homeostatic agents 2003;17(3):223-33.
2003: Dijkstra-Tiekstra M J; Schrijver J G; van der Meer P F; Laport R F; Gratama J W; Levering W H B M; van Delden C J; de Wildt-Eggen J
Crossover study of three methods for low-level white blood cell counting on two types of flow cytometer.
Cytometry. Part B, Clinical cytometry 2003;54(1):39-45.
2003: Levering Wilfried H B M; Wind Henk; Sintnicolaas Kees; Hooijkaas Herbert; Gratama Jan W
Flow cytometric HLA-B27 screening: cross-reactivity patterns of commercially available anti-HLA-B27 monoclonal antibodies with other HLA-B antigens.
Cytometry. Part B, Clinical cytometry 2003;54(1):28-38.
2003: Sutherland Robert; Keeney Michael; Gratama Jan W
Quantification of CD34 epitopes in AML.
Haematologica 2003;88(6):ELT22; author reply ELT23.
2003: Meij Pauline; van Esser Joost W J; Niesters Hubert G M; van Baarle Debbie; Miedema Frank; Blake Neil; Rickinson Alan B; Leiner Ingrid; Pamer Eric; Lowenberg Bob; Cornelissen Jan J; Gratama Jan W
Impaired recovery of Epstein-Barr virus (EBV)--specific CD8+ T lymphocytes after partially T-depleted allogeneic stem cell transplantation may identify patients at very high risk for progressive EBV reactivation and lymphoproliferative disease.
Blood 2003;101(11):4290-7.
2003: Portielje Johanna E A; Gratama Jan Willem; van Ojik Heidi H; Stoter Gerrit; Kruit Wim H J
IL-12: a promising adjuvant for cancer vaccination.
Cancer immunology, immunotherapy : CII 2003;52(3):133-44.
2003: Schaft Niels; Willemsen Ralph A; de Vries Jolanda; Lankiewicz Birgit; Essers Bram W L; Gratama Jan-Willem; Figdor Carl G; Bolhuis Reinier L H; Debets Reno; Adema Gosse J
Peptide fine specificity of anti-glycoprotein 100 CTL is preserved following transfer of engineered TCR alpha beta genes into primary human T lymphocytes.
Journal of immunology (Baltimore, Md. : 1950) 2003;170(4):2186-94.
2003: Portielje Johanna E A; Lamers Cor H J; Kruit Wim H J; Sparreboom Alex; Bolhuis Reinder L H; Stoter Gerrit; Huber Christoph; Gratama Jan W
Repeated administrations of interleukin (IL)-12 are associated with persistently elevated plasma levels of IL-10 and declining IFN-gamma, tumor necrosis factor-alpha, IL-6, and IL-8 responses.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(1):76-83.
2003: Gratama Jan W; Cornelissen Jan J
Clinical utility of tetramer-based immune monitoring in allogeneic stem cell transplantation.
BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy 2003;17(5):325-38.
2003: Gratama J W; Kraan J; Keeney M; Sutherland D R; Granger V; Barnett D
Validation of the single-platform ISHAGE method for CD34(+) hematopoietic stem and progenitor cell enumeration in an international multicenter study.
Cytotherapy 2003;5(1):55-65.
2002: Chianese R; Brando B; Gratama J W;
Diagnostic and prognostic value of flow cytometric immunophenotyping in malignant hematological diseases.
Journal of biological regulators and homeostatic agents 2002;16(4):259-69.
2002: Sebestyén Zsolt; Nagy Péter; Horváth Gábor; Vámosi György; Debets Reno; Gratama Jan W; Alexander Denis R; Szöllosi János
Long wavelength fluorophores and cell-by-cell correction for autofluorescence significantly improves the accuracy of flow cytometric energy transfer measurements on a dual-laser benchtop flow cytometer.
Cytometry 2002;48(3):124-35.
2002: Kern Florian; Bunde Torsten; Faulhaber Nicole; Kiecker Felix; Khatamzas Elham; Rudawski Ina-Maria; Pruss Axel; Gratama Jan-Willem; Volkmer-Engert Rudolf; Ewert Ralf; Reinke Petra; Volk Hans-Dieter; Picker Louis J
Cytomegalovirus (CMV) phosphoprotein 65 makes a large contribution to shaping the T cell repertoire in CMV-exposed individuals.
The Journal of infectious diseases 2002;185(12):1709-16.
2002: van Esser Joost W J; Niesters Hubert G M; van der Holt Bronno; Meijer Ellen; Osterhaus Albert D M E; Gratama Jan Willem; Verdonck Leo F; Löwenberg Bob; Cornelissen Jan J
Prevention of Epstein-Barr virus-lymphoproliferative disease by molecular monitoring and preemptive rituximab in high-risk patients after allogeneic stem cell transplantation.
Blood 2002;99(12):4364-9.
2002: Gratama Jan W; Kraan Jaco; Keeney Mike; Granger Viv; Barnett David
Reduction of variation in T-cell subset enumeration among 55 laboratories using single-platform, three or four-color flow cytometry based on CD45 and SSC-based gating of lymphocytes.
Cytometry 2002;50(2):92-101.
2002: van den Bent M J; Lamers C H J; van 't Veer M B; Sillevis Smitt P A E; Bolhuis R L H; Gratama J W
Increased levels of soluble CD27 in the cerebrospinal fluid are not diagnostic for leptomeningeal involvement by lymphoid malignancies.
Annals of hematology 2002;81(4):187-91.
2001: van der Meer P F; Gratama J W; van Delden C J; Laport R F; Levering W H; Schrijver J G; Tiekstra M J; Keeney M; de Wildt-Eggen J
Comparison of five platforms for enumeration of residual leucocytes in leucoreduced blood components.
British journal of haematology 2001;115(4):953-62.
2001: Gratama J W; van Esser J W; Lamers C H; Tournay C; Löwenberg B; Bolhuis R L; Cornelissen J J
Tetramer-based quantification of cytomegalovirus (CMV)-specific CD8+ T lymphocytes in T-cell-depleted stem cell grafts and after transplantation may identify patients at risk for progressive CMV infection.
Blood 2001;98(5):1358-64.
2001: van Esser J W; van der Holt B; Meijer E; Niesters H G; Trenschel R; Thijsen S F; van Loon A M; Frassoni F; Bacigalupo A; Schaefer U W; Osterhaus A D; Gratama J W; Löwenberg B; Verdonck L F; Cornelissen J J
Epstein-Barr virus (EBV) reactivation is a frequent event after allogeneic stem cell transplantation (SCT) and quantitatively predicts EBV-lymphoproliferative disease following T-cell--depleted SCT.
Blood 2001;98(4):972-8.
2001: van Esser J W; Niesters H G; Thijsen S F; Meijer E; Osterhaus A D; Wolthers K C; Boucher C A; Gratama J W; Budel L M; van der Holt B; van Loon A M; Löwenberg B; Verdonck L F; Cornelissen J J
Molecular quantification of viral load in plasma allows for fast and accurate prediction of response to therapy of Epstein-Barr virus-associated lymphoproliferative disease after allogeneic stem cell transplantation.
British journal of haematology 2001;113(3):814-21.
2001: Gratama J W; Sutherland D R; Keeney M; Papa S
Flow cytometric enumeration and immunophenotyping of hematopoietic stem and progenitor cells.
Journal of biological regulators and homeostatic agents 2001;15(1):14-22.
2000: Brando B; Barnett D; Janossy G; Mandy F; Autran B; Rothe G; Scarpati B; D'Avanzo G; D'Hautcourt J L; Lenkei R; Schmitz G; Kunkl A; Chianese R; Papa S; Gratama J W
Cytofluorometric methods for assessing absolute numbers of cell subsets in blood. European Working Group on Clinical Cell Analysis.
Cytometry 2000;42(6):327-46.
2000: Willemsen R A; Weijtens M E; Ronteltap C; Eshhar Z; Gratama J W; Chames P; Bolhuis R L
Grafting primary human T lymphocytes with cancer-specific chimeric single chain and two chain TCR.
Gene therapy 2000;7(16):1369-77.
2000: Gratama J W; Menéndez P; Kraan J; Orfao A
Loss of CD34(+) hematopoietic progenitor cells due to washing can be reduced by the use of fixative-free erythrocyte lysing reagents.
Journal of immunological methods 2000;239(1-2):13-23.
2000: Levering W H; van den Beemd R; te Marvelde J G; van Beers W A; Hooijkaas H; Sintnicolaas K; Gratama J W
External quality assessment of flow cytometric HLA-B27 typing.
Cytometry 2000;42(2):95-105.
2000: Broers A E; van Der Holt R; van Esser J W; Gratama J W; Henzen-Logmans S; Kuenen-Boumeester V; Löwenberg B; Cornelissen J J
Increased transplant-related morbidity and mortality in CMV-seropositive patients despite highly effective prevention of CMV disease after allogeneic T-cell-depleted stem cell transplantation.
Blood 2000;95(7):2240-5.
2000: Barnett D; Granger V; Kraan J; Whitby L; Reilly J T; Papa S; Gratama J W
Reduction of intra- and interlaboratory variation in CD34+ stem cell enumeration using stable test material, standard protocols and targeted training. DK34 Task Force of the European Working Group of Clinical Cell Analysis (EWGCCA).
British journal of haematology 2000;108(4):784-92.
1999: Gratama J W; Braakman E; Kraan J; Lankheet P; Levering W H; Van Den Beemd M W; Van Der Schoot C E; Wijermans P; Preijers F
Comparison of single and dual-platform assay formats for CD34+ haematopoietic progenitor cell enumeration.
Clinical and laboratory haematology 1999;21(5):337-46.
1999: Gratama J W; Bolhuis R L; Van 't Veer M B
Quality control of flow cytometric immunophenotyping of haematological malignancies.
Clinical and laboratory haematology 1999;21(3):155-60.
1999: Gadisseur A P; Gratama J W; Lamers C; van Esser J W; Bolhuis R L; Cornelissen J J
Expression of T cell activation antigen CD134 (OX40) has no predictive value for the occurrence or response to therapy of acute graft-versus-host disease in partial T cell-depleted bone marrow transplantation.
Bone marrow transplantation 1999;23(10):1013-7.
1998: Lenkei R; Gratama J W; Rothe G; Schmitz G; D'hautcourt J L; Arekrans A; Mandy F; Marti G
Performance of calibration standards for antigen quantitation with flow cytometry.
Cytometry 1998;33(2):188-96.
1998: Gratama J W; D'hautcourt J L; Mandy F; Rothe G; Barnett D; Janossy G; Papa S; Schmitz G; Lenkei R
Flow cytometric quantitation of immunofluorescence intensity: problems and perspectives. European Working Group on Clinical Cell Analysis.
Cytometry 1998;33(2):166-78.
1998: Gratama J W; Orfao A; Barnett D; Brando B; Huber A; Janossy G; Johnsen H E; Keeney M; Marti G E; Preijers F; Rothe G; Serke S; Sutherland D R; Van der Schoot C E; Schmitz G; Papa S
Flow cytometric enumeration of CD34+ hematopoietic stem and progenitor cells. European Working Group on Clinical Cell Analysis.
Cytometry 1998;34(3):128-42.
1998: Bolhuis R L; Willemsen R A; Lamers C H; Stam K; Gratama J W; Weijtens M E
Preparation for a phase I/II study using autologous gene modified T lymphocytes for treatment of metastatic renal cancer patients.
Advances in experimental medicine and biology 1998;451():547-55.
1997: Gratama J W; van der Linden R; van der Holt B; Bolhuis R L; van de Winkel J G
Analysis of factors contributing to the formation of mononuclear cell aggregates ("escapees") in flow cytometric immunophenotyping.
Cytometry 1997;29(3):250-60.
1997: Lamers C H; Bolhuis R L; Warnaar S O; Stoter G; Gratama J W
Local but no systemic immunomodulation by intraperitoneal treatment of advanced ovarian cancer with autologous T lymphocytes re-targeted by a bi-specific monoclonal antibody.
International journal of cancer. Journal international du cancer 1997;73(2):211-9.
1997: Gratama J W; Kraan J; Van den Beemd R; Hooibrink B; Van Bockstaele D R; Hooijkaas H
Analysis of variation in results of flow cytometric lymphocyte immunophenotyping in a multicenter study.
Cytometry 1997;30(4):166-77.
1997: Gratama J W; Kraan J; Levering W; Van Bockstaele D R; Rijkers G T; Van der Schoot C E
Analysis of variation in results of CD34+ hematopoietic progenitor cell enumeration in a multicenter study.
Cytometry 1997;30(3):109-17.
1997: Gratama J W; Kraan J; Adriaansen H; Hooibrink B; Levering W; Reinders P; Van den Beemd M W; Van der Holt B; Bolhuis R L
Reduction of interlaboratory variability in flow cytometric immunophenotyping by standardization of instrument set-up and calibration, and standard list mode data analysis.
Cytometry 1997;30(1):10-22.
1993: van Putten W L; de Vries W; Reinders P; Levering W; van der Linden R; Tanke H J; Bolhuis R L; Gratama J W
Quantification of fluorescence properties of lymphocytes in peripheral blood mononuclear cell suspensions using a latent class model.
Cytometry 1993;14(1):86-96.

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