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Georges Grau

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Mark J Hackett; Nicholas H Hunt; Elizabeth A Carter; Fatima El-Assaad; Georges E Grau; Joonsup Lee; James A McQuillan; Peter A Lay
FTIR imaging of brain tissue reveals crystalline creatine deposits are an ex vivo marker of localized ischemia during murine cerebral malaria: general implications for disease neurochemistry.
Dorothée Faille; Thierry Fusai; Georges E Grau; Andrew J Mitchell; Marie-Christine Alessi; Giovanna Chimini; Fatima El-Assaad; Valéry Combes
Endocytosis and intracellular processing of platelet microparticles by brain endothelial cells.
Raman Saggu; Patrick J Cozzone; Dorothée Faille; Georges E Grau; Angèle Viola
In the eye of experimental cerebral malaria.

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2012: Mark J Hackett; Nicholas H Hunt; Elizabeth A Carter; Fatima El-Assaad; Georges E Grau; Joonsup Lee; James A McQuillan; Peter A Lay
FTIR imaging of brain tissue reveals crystalline creatine deposits are an ex vivo marker of localized ischemia during murine cerebral malaria: general implications for disease neurochemistry.
ACS chemical neuroscience 2012;3(12):1017-24.
2012: Dorothée Faille; Thierry Fusai; Georges E Grau; Andrew J Mitchell; Marie-Christine Alessi; Giovanna Chimini; Fatima El-Assaad; Valéry Combes
Endocytosis and intracellular processing of platelet microparticles by brain endothelial cells.
Journal of cellular and molecular medicine 2012;16(8):1731-8.
2011: Raman Saggu; Patrick J Cozzone; Dorothée Faille; Georges E Grau; Angèle Viola
In the eye of experimental cerebral malaria.
The American journal of pathology 2011;179(3):1104-9.
2011: Mathieu Barbier; Dorothée Faille; Béatrice Loriod; Julien Textoris; Claire Camus; Denis Puthier; Laurence Flori; Samuel Crocodile Wassmer; Geneviève Victorero; Marie-Christine Alessi; Thierry Fusaï; Catherine Nguyen; Georges E Grau; Pascal Rihet
Platelets alter gene expression profile in human brain endothelial cells in an in vitro model of cerebral malaria.
PloS one 2011;6(5):e19651.
2009: Wen-jian Zhang; Lian-qiu Wu; Hong-lin Liu; Li-ya Ye; Yu-ling Xin; Georges E Grau; Jin-Ning Lou
Abnormal blood vessels formed by human liver cavernous hemangioma endothelial cells in nude mice are suitable for drug evaluation.
Microvascular research 2009;78(3):379-85.
2009: Yassina Bechah; Christian Capo; Georges E Grau; Didier Raoult; Jean-Louis Mege
Rickettsia prowazekii infection of endothelial cells increases leukocyte adhesion through alphavbeta3 integrin engagement.
Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 2009;15 Suppl 2():249-50.
2008: Marie-France Penet; Mhamad Abou-Hamdan; Nicolas Coltel; Emilie Cornille; Georges E Grau; Max de Reggi; Bouchra Gharib
Protection against cerebral malaria by the low-molecular-weight thiol pantethine.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(4):1321-6.
2008: Samuel Wassmer; Terrie E Taylor; Calman Alexander Maclennan; Maxwell Kanjala; Mavuto Mukaka; Malcolm E Molyneux; Georges E Grau
Platelet-induced clumping of Plasmodium falciparum-infected erythrocytes from Malawian patients with cerebral malaria-possible modulation in vivo by thrombocytopenia.
The Journal of infectious diseases 2008;197(1):72-8.
2008: Lian-Qiu Wu; Wen Jian Zhang; Ji Xiao Niu; Li-Ya Ye; Zhi-Hua Yang; Georges E Grau; Jin-Ning Lou
Phenotypic and functional differences between human liver cancer endothelial cells and liver sinusoidal endothelial cells.
Journal of vascular research 2008;45(1):78-86.
2007: Ji Xiao Niu; Wen Jian Zhang; Li-Ya Ye; Lian-Qiu Wu; Guang-jin Zhu; Zhi-Hua Yang; Georges E Grau; Jin-Ning Lou
The role of adhesion molecules, alpha v beta 3, alpha v beta 5 and their ligands in the tumor cell and endothelial cell adhesion.
European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) 2007;16(6):517-27.
2007: Yassina Bechah; Christian Capo; Georges E Grau; Didier Raoult; Jean-Louis Mege
A murine model of infection with Rickettsia prowazekii: implications for pathogenesis of epidemic typhus.
Microbes and infection / Institut Pasteur 2007;9(7):898-906.
2007: Marie-France Penet; Frank Kober; Sylviane Confort-Gouny; Yann Le Fur; Christiane Dalmasso; Nicolas Coltel; Agnès Liprandi; Jean-Marc Gulian; Georges E Grau; Patrick J Cozzone; Angèle Viola
Magnetic resonance spectroscopy reveals an impaired brain metabolic profile in mice resistant to cerebral malaria infected with Plasmodium berghei ANKA.
The Journal of biological chemistry 2007;282(19):14505-14.
2007: Nicolas F Delahaye; Nicolas Coltel; Denis Puthier; Mathieu Barbier; Philippe Benech; Florence Joly; Fuad A Iraqi; Georges E Grau; Catherine Nguyen; Pascal Rihet
Gene expression analysis reveals early changes in several molecular pathways in cerebral malaria-susceptible mice versus cerebral malaria-resistant mice.
BMC genomics 2007;8():452.
2006: Soraya Meghari; Benoît Desnues; Christian Capo; Georges E Grau; Didier Raoult; Jean-Louis Mege
Coxiella burnetii stimulates production of RANTES and MCP-1 by mononuclear cells: modulation by adhesion to endothelial cells and its implication in Q fever.
European cytokine network 2006;17(4):253-9.
2006: Henri C Van Der Heyde; John Nolan; Valéry Combes; Irene Gramaglia; Georges E Grau
A unified hypothesis for the genesis of cerebral malaria: sequestration, inflammation and hemostasis leading to microcirculatory dysfunction.
Trends in parasitology 2006;22(11):503-8.
2006: Nicolas Coltel; Valéry Combes; Samuel Wassmer; Giovanna Chimini; Georges E Grau
Cell vesiculation and immunopathology: implications in cerebral malaria.
Microbes and infection / Institut Pasteur 2006;8(8):2305-16.
2006: Valéry Combes; Nicolas Coltel; Dorothée Faille; Samuel Wassmer; Georges E Grau
Cerebral malaria: role of microparticles and platelets in alterations of the blood-brain barrier.
International journal for parasitology 2006;36(5):541-6.
2006: Samuel Wassmer; George J Cianciolo; Valéry Combes; Georges E Grau
[LMP-420, a new therapeutic approach for cerebral malaria?].
Médecine sciences : M/S 2006;22(4):343-5.
2006: Soraya Meghari; Jean-Marc ROLAIN; Georges E Grau; Esther Platt; Lina Barrassi; Jean-Louis Mege; Didier Raoult
Antiangiogenic effect of erythromycin: an in vitro model of Bartonella quintana infection.
The Journal of infectious diseases 2006;193(3):380-6.
2006: Samuel Wassmer; J Brian de Souza; Corinne Frère; Francisco J Candal; Irène Juhan-Vague; Georges E Grau
TGF-beta1 released from activated platelets can induce TNF-stimulated human brain endothelium apoptosis: a new mechanism for microvascular lesion during cerebral malaria.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(2):1180-4.
2006: Nicolas F Delahaye; Nicolas Coltel; Denis Puthier; Laurence Flori; Rémi Houlgatte; Fuad A Iraqi; Catherine Nguyen; Georges E Grau; Pascal Rihet
Gene-expression profiling discriminates between cerebral malaria (CM)-susceptible mice and CM-resistant mice.
The Journal of infectious diseases 2006;193(2):312-21.
2006: Wen-Jian Zhang; Li-Ya Ye; Lian-Qiu Wu; Yu-Ling Xin; Feng Gu; Ji Xiao Niu; Zhi-Hua Yang; Guang-jin Zhu; Georges E Grau; Jin-Ning Lou
Morphologic, phenotypic and functional characteristics of endothelial cells derived from human hepatic cavernous hemangioma.
Journal of vascular research 2006;43(6):522-32.
2006: Samuel Wassmer; Valéry Combes; Francisco J Candal; Irène Juhan-Vague; Georges E Grau
Platelets potentiate brain endothelial alterations induced by Plasmodium falciparum.
Infection and immunity 2006;74(1):645-53.
2005: Samuel Wassmer; George J Cianciolo; Valéry Combes; Georges E Grau
Inhibition of endothelial activation: a new way to treat cerebral malaria?
PLoS medicine 2005;2(9):e245.
2005: Marie-France Penet; Angèle Viola; Sylviane Confort-Gouny; Yann Le Fur; Guillaume Duhamel; Frank Kober; Danielle Ibarrola; Marguerite Izquierdo; Nicolas Coltel; Bouchra Gharib; Georges E Grau; Patrick J Cozzone
Imaging experimental cerebral malaria in vivo: significant role of ischemic brain edema.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2005;25(32):7352-8.
2005: Valéry Combes; Nicolas Coltel; Mélanie Alibert; Miranda van Eck; Cécile Raymond; Irène Juhan-Vague; Georges E Grau; Giovanna Chimini
ABCA1 gene deletion protects against cerebral malaria: potential pathogenic role of microparticles in neuropathology.
The American journal of pathology 2005;166(1):295-302.
2004: Valéry Combes; Terrie E Taylor; Irène Juhan-Vague; Jean-Louis Mège; James Mwenechanya; Madalitso Tembo; Georges E Grau; Malcolm E Molyneux
Circulating endothelial microparticles in malawian children with severe falciparum malaria complicated with coma.
JAMA : the journal of the American Medical Association 2004;291(21):2542-4.
2004: Nicolas Coltel; Valéry Combes; Nicholas H Hunt; Georges E Grau
Cerebral malaria -- a neurovascular pathology with many riddles still to be solved.
Current neurovascular research 2004;1(2):91-110.
2004: Valéry Combes; Alexander R Rosenkranz; Mireille Redard; Giampaolo Pizzolato; Hubert Lepidi; Dietmar Vestweber; Tanya N Mayadas; Georges E Grau
Pathogenic role of P-selectin in experimental cerebral malaria: importance of the endothelial compartment.
The American journal of pathology 2004;164(3):781-6.
2004: Samuel Wassmer; Catherine LéPolard; Boubacar Traoré; Bruno Pouvelle; Jurg Gysin; Georges E Grau
Platelets reorient Plasmodium falciparum-infected erythrocyte cytoadhesion to activated endothelial cells.
The Journal of infectious diseases 2004;189(2):180-9.
2004: Valéry Combes; Georges E Grau
["Molecular approaches to malaria" (MAM 2004) Lorne-Victoria, Australia, February 1-5, 2004].
Médecine tropicale : revue du Corps de santé colonial 2004;64(4):401-4.
2003: Samuel Wassmer; Valéry Combes; Georges E Grau
Pathophysiology of cerebral malaria: role of host cells in the modulation of cytoadhesion.
Annals of the New York Academy of Sciences 2003;992():30-8.
2003: Georges E Grau; Charles Mackenzie; Richard A Carr; Mireille Redard; Giampaolo Pizzolato; Claude Allasia; Claude Cataldo; Terrie E Taylor; Malcolm E Molyneux
Platelet accumulation in brain microvessels in fatal pediatric cerebral malaria.
The Journal of infectious diseases 2003;187(3):461-6.
2003: Samuel Wassmer; Nicolas Coltel; Valéry Combes; Georges E Grau
[Pathogenesis of cerebral malaria: facts and hypotheses].
Médecine tropicale : revue du Corps de santé colonial 2003;63(3):254-7.
2002: Benjamin Stoelcker; Thomas Hehlgans; Karin Weigl; Horst Bluethmann; Georges E Grau; Daniela N Männel
Requirement for tumor necrosis factor receptor 2 expression on vascular cells to induce experimental cerebral malaria.
Infection and immunity 2002;70(10):5857-9.
2002: Jürg Hamacher; Rudolf Lucas; H Roger Lijnen; Susanne Buschke; Yves Dunant; Albrecht Wendel; Georges E Grau; Peter M Suter; Bara Ricou
Tumor necrosis factor-alpha and angiostatin are mediators of endothelial cytotoxicity in bronchoalveolar lavages of patients with acute respiratory distress syndrome.
American journal of respiratory and critical care medicine 2002;166(5):651-6.
2001: Stephan Harbarth; K Holeckova; C Froidevaux; Didier Pittet; Bara Ricou; Georges E Grau; L Vadas; Jérôme Pugin
Diagnostic value of procalcitonin, interleukin-6, and interleukin-8 in critically ill patients admitted with suspected sepsis.
American journal of respiratory and critical care medicine 2001;164(3):396-402.
2001: Rudolf Lucas; R Montesano; Michael S Pepper; M Hafner; E Sablon; Yves Dunant; Georges E Grau; Patrick De Baetselier; Daniela N Männel; L Fransen
Lectin-deficient TNF mutants display comparable anti-tumour but reduced pro-metastatic potential as compared to the wild-type molecule.
International journal of cancer. Journal international du cancer 2001;91(4):543-9.
2000: Pierre-François Piguet; C Da Laperrousaz; Christian Vesin; Fabienne Tacchini-Cottier; Giorgio Senaldi; Georges E Grau
Delayed mortality and attenuated thrombocytopenia associated with severe malaria in urokinase- and urokinase receptor-deficient mice.
Infection and immunity 2000;68(7):3822-9.
2000: Jérôme Dellacasagrande; P A Moulin; C Guilianelli; Christian Capo; Didier Raoult; Georges E Grau; Jean-Louis Mege
Reduced transendothelial migration of monocytes infected by Coxiella burnetii.
Infection and immunity 2000;68(6):3784-6.
1999: Marusa Hribar; Alain Bloc; F Gisou van der Goot; L Fransen; Patrick De Baetselier; Georges E Grau; H Bluethmann; M A Matthay; Yves Dunant; Jérôme Pugin; Rudolf Lucas
The lectin-like domain of tumor necrosis factor-alpha increases membrane conductance in microvascular endothelial cells and peritoneal macrophages.
European journal of immunology 1999;29(10):3105-11.
1999: J Lou; Yvan Gasche; L Zheng; Christian Giroud; Philippe Morel; J Clements; A Ythier; Georges E Grau
Interferon-beta inhibits activated leukocyte migration through human brain microvascular endothelial cell monolayer.
Laboratory investigation; a journal of technical methods and pathology 1999;79(8):1015-25.
1999: Bernhard Nieswandt; Bernd Echtenacher; Frank-Peter Wachs; J Schröder; J Engelbert Gessner; R E Schmidt; Georges E Grau; Daniela N Männel
Acute systemic reaction and lung alterations induced by an antiplatelet integrin gpIIb/IIIa antibody in mice.
Blood 1999;94(2):684-93.
1999: Valéry Combes; A C Simon; Georges E Grau; Dominique Arnoux; Laurence Camoin; Florence Sabatier; Murielle Mutin; Marielle Sanmarco; José Sampol; Françoise Dignat-George
In vitro generation of endothelial microparticles and possible prothrombotic activity in patients with lupus anticoagulant.
The Journal of clinical investigation 1999;104(1):93-102.
1999: T Berney; Yvan Gasche; J Robert; A Jenny; Noury Mensi; Georges E Grau; Bernard Vermeulen; Philippe Morel
Serum profiles of interleukin-6, interleukin-8, and interleukin-10 in patients with severe and mild acute pancreatitis.
Pancreas 1999;18(4):371-7.
1998: Rudolf Lucas; L Holmgren; IRENE GARCIA; B Jimenez; Stefano J Mandriota; F Borlat; B K Sim; Z Wu; Georges E Grau; Yuen Shing; Gerald A Soff; Noel P Bouck; Michael S Pepper
Multiple forms of angiostatin induce apoptosis in endothelial cells.
Blood 1998;92(12):4730-41.
1998: Jinning Lou; Yvan Gasche; L Zheng; B Critico; Christine Monso-Hinard; P Juillard; P Morel; WA Buurman; Georges E Grau
Differential reactivity of brain microvascular endothelial cells to TNF reflects the genetic susceptibility to cerebral malaria.
European journal of immunology 1998;28(12):3989-4000.
1998: Rudolf Lucas; IRENE GARCIA; Yves Donati; Marusa Hribar; Stefano J Mandriota; Christian Giroud; WA Buurman; L Fransen; P M Suter; Gabriel Nunez; Michael S Pepper; Georges E Grau
Both TNF receptors are required for direct TNF-mediated cytotoxicity in microvascular endothelial cells.
European journal of immunology 1998;28(11):3577-86.
1998: Jin-Ning Lou; N Mili; C Decrind; Yves Donati; S Kossodo; A Spiliopoulos; Bara Ricou; P M Suter; D R Morel; P Morel; Georges E Grau
An improved method for isolation of microvascular endothelial cells from normal and inflamed human lung.
In vitro cellular & developmental biology. Animal 1998;34(7):529-36.
1997: Antonio Carota; GP Pizzolato; Mireille Redard; Philippe Gailloud; Georges E Grau
Adhesion molecules in HIV-related and idiopathic polymyositis: immunohistochemical studies.
Clinical neuropathology 1997;16(6):312-8.
1997: Jinning Lou; Yves Donati; P Juillard; Christian Giroud; Christian Vesin; N Mili; Georges E Grau
Platelets play an important role in TNF-induced microvascular endothelial cell pathology.
The American journal of pathology 1997;151(5):1397-405.
1997: Christine Monso-Hinard; Jin-Ning Lou; C Behr; P Juillard; Georges E Grau
Expression of major histocompatibility complex antigens on mouse brain microvascular endothelial cells in relation to susceptibility to cerebral malaria.
Immunology 1997;92(1):53-9.
1997: Michel Chofflon; S Roth; C Juillard; A M Paunier; P Juillard; D Degroote; Georges E Grau
Tumor necrosis factor production capacity as a potentially useful parameter to monitor disease activity in multiple sclerosis.
European cytokine network 1997;8(3):253-7.
1997: S Kossodo; C Monso; P Juillard; T Velu; M Goldman; Georges E Grau
Interleukin-10 modulates susceptibility in experimental cerebral malaria.
Immunology 1997;91(4):536-40.
1997: Daniela N Männel; Georges E Grau
Role of platelet adhesion in homeostasis and immunopathology.
Molecular pathology : MP 1997;50(4):175-85.
1997: Rudolf Lucas; P Juillard; E Decoster; Mireille Redard; D Burger; Yves Donati; Christian Giroud; Christine Monso-Hinard; T De Kesel; WA Buurman; M W Moore; Jean-Michel Dayer; Walter Fiers; H Bluethmann; Georges E Grau
Crucial role of tumor necrosis factor (TNF) receptor 2 and membrane-bound TNF in experimental cerebral malaria.
European journal of immunology 1997;27(7):1719-25.
1997: Jinning Lou; A Ythier; D Burger; L Zheng; P Juillard; Rudolf Lucas; Jean-Michel Dayer; Georges E Grau
Modulation of soluble and membrane-bound TNF-induced phenotypic and functional changes of human brain microvascular endothelial cells by recombinant TNF binding protein I.
Journal of neuroimmunology 1997;77(1):107-15.
1997: Rudolf Lucas; Bernd Echtenacher; E Sablon; P Juillard; S Magez; Jinning Lou; Yves Donati; F Bosman; A Van de Voorde; L Fransen; Daniela N Männel; Georges E Grau; Patrick De Baetselier
Generation of a mouse tumor necrosis factor mutant with antiperitonitis and desensitization activities comparable to those of the wild type but with reduced systemic toxicity.
Infection and immunity 1997;65(6):2006-10.
1997: Rudolf Lucas; Jinning Lou; D R Morel; Bara Ricou; Peter M Suter; Georges E Grau
TNF receptors in the microvascular pathology of acute respiratory distress syndrome and cerebral malaria.
Journal of leukocyte biology 1997;61(5):551-8.
1997: Benjamin Mordmüller; W G Metzger; P Juillard; BM Brinkman; C L Verweij; Georges E Grau; P G Kremsner
Tumor necrosis factor in Plasmodium falciparum malaria: high plasma level is associated with fever, but high production capacity is associated with rapid fever clearance.
European cytokine network 1997;8(1):29-35.
1997: Jinning Lou; Michel Chofflon; C Juillard; Yves Donati; N Mili; C A Siegrist; Georges E Grau
Brain microvascular endothelial cells and leukocytes derived from patients with multiple sclerosis exhibit increased adhesion capacity.
Neuroreport 1997;8(3):629-33.
1997: Rudolf Lucas; Jin-Ning Lou; P Juillard; M Moore; H Bluethmann; Georges E Grau
Respective role of TNF receptors in the development of experimental cerebral malaria.
Journal of neuroimmunology 1997;72(2):143-8.
1996: Georges E Grau; N Mili; Jin-Ning Lou; D R Morel; Bara Ricou; Rudolf Lucas; P M Suter
Phenotypic and functional analysis of pulmonary microvascular endothelial cells from patients with acute respiratory distress syndrome.
Laboratory investigation; a journal of technical methods and pathology 1996;74(4):761-70.
1995: Fabienne Tacchini-Cottier; Jin-Ning Lou; D J Roberts; A M Garcia; Georges E Grau
Detection of a LFA-1-like epitope on the surface of erythrocytes infected with a strain of Plasmodium falciparum.
Immunology 1995;85(2):205-13.
1994: Georges E Grau; S de Kossodo
Cerebral malaria: mediators, mechanical obstruction or more?
Parasitology today (Personal ed.) 1994;10(10):408-9.
1994: Georges E Grau; C Behr
T cells and malaria: is Th1 cell activation a prerequisite for pathology?
Research in immunology 1994;145(6):441-54.
1994: Leo H Bühler; S Deng; Georges E Grau; G Mentha; A Rohner; Philippe Morel
Treatment with antibodies to leucocyte function-associated antigen-1 prolongs the survival of xenotransplanted islets of Langerhans.
Transplantation proceedings 1994;26(3):1360-1.
1994: S Deng; Leo H Bühler; Jinning Lou; Georges E Grau; M Redard; C Bubloz; A Rohner; Philippe Morel
Study of concordant xenografted islets of Langerhans rejection: humoral or cellular mechanism?
Transplantation proceedings 1994;26(3):1184-5.
1994: G Senaldi; P Pointaire; Pierre-François Piguet; Georges E Grau
Protective effect of N-acetylcysteine in hapten-induced irritant and contact hypersensitivity reactions.
The Journal of investigative dermatology 1994;102(6):934-7.
1994: S de Kossodo; Georges E Grau; Jacques A Louis; Ingrid Müller
Tumor necrosis factor alpha (TNF-alpha) and TNF-beta and their receptors in experimental cutaneous leishmaniasis.
Infection and immunity 1994;62(4):1414-20.
1994: G Senaldi; Christian Vesin; R Chang; Georges E Grau; Pierre-François Piguet
Role of polymorphonuclear neutrophil leukocytes and their integrin CD11a (LFA-1) in the pathogenesis of severe murine malaria.
Infection and immunity 1994;62(4):1144-9.
1994: S de Kossodo; B Critico; Georges E Grau
Modulation of the transcripts for tumor necrosis factor-alpha and its receptors in vivo.
European journal of immunology 1994;24(3):769-72.
1994: Fabienne Tacchini-Cottier; Georges E Grau
[Cytokines and malaria].
Médecine tropicale : revue du Corps de santé colonial 1994;54(3):257-62.
1993: Georges E Grau; Fabienne Tacchini-Cottier; Christian Vesin; G Milon; Jin-Ning Lou; Pierre-François Piguet; P Juillard
TNF-induced microvascular pathology: active role for platelets and importance of the LFA-1/ICAM-1 interaction.
European cytokine network 1993;4(6):415-9.
1993: Pierre-François Piguet; Christian Vesin; J E Ryser; G Senaldi; Georges E Grau; Fabienne Tacchini-Cottier
An effector role for platelets in systemic and local lipopolysaccharide-induced toxicity in mice, mediated by a CD11a- and CD54-dependent interaction with endothelium.
Infection and immunity 1993;61(10):4182-7.
1993: A Ythier; M P Gascon; P Juillard; Christian Vesin; David Wallach; Georges E Grau
Protective effect of natural TNF-binding protein on human TNF-induced toxicity in mice.
Cytokine 1993;5(5):459-62.
1993: Pierre-François Piguet; Georges E Grau; S de Kossodo
Role of granulocyte-macrophage colony-stimulating factor in pulmonary fibrosis induced in mice by bleomycin.
Experimental lung research 1993;19(5):579-87.
1993: H R Chang; Christian Vesin; Georges E Grau; P Pointaire; Denis Arsenijevic; M Strath; Jean-Claude Pechère; Pierre-François Piguet
Respective role of polymorphonuclear leukocytes and their integrins (CD-11/18) in the local or systemic toxicity of lipopolysaccharide.
Journal of leukocyte biology 1993;53(6):636-9.
1993: S K Parida; Georges E Grau
Role of TNF in immunopathology of leprosy.
Research in immunology 1993;144(5):376-84.
1993: Georges E Grau; J Lou
TNF in vascular pathology: the importance of platelet-endothelium interactions.
Research in immunology 1993;144(5):355-63.
1993: J Porta; A Carota; G P Pizzolato; E Wildi; M C Widmer; C Margairaz; Georges E Grau
Immunopathological changes in human cerebral malaria.
Clinical neuropathology 1993;12(3):142-6.
1993: Pierre-François Piguet; H Rosen; Christian Vesin; Georges E Grau
Effective treatment of the pulmonary fibrosis elicited in mice by bleomycin or silica with anti-CD-11 antibodies.
The American review of respiratory disease 1993;147(2):435-41.
1993: Georges E Grau; P H Lambert; P Vassalli; Pierre-François Piguet
Tumor necrosis factor/cachectin as an effector of T cell-dependent immunopathology.
International review of experimental pathology 1993;34 Pt B():159-71.
1993: Pierre-François Piguet; Christian Vesin; Georges E Grau; R C Thompson
Interleukin 1 receptor antagonist (IL-1ra) prevents or cures pulmonary fibrosis elicited in mice by bleomycin or silica.
Cytokine 1993;5(1):57-61.
1992: A Desmoulière; Laura Rubbia-Brandt; Georges E Grau; Giulio Gabbiani
Heparin induces alpha-smooth muscle actin expression in cultured fibroblasts and in granulation tissue myofibroblasts.
Laboratory investigation; a journal of technical methods and pathology 1992;67(6):716-26.
1992: Pierre-François Piguet; Georges E Grau; Christian Vesin; Hansruedi Loetscher; R Gentz; W Lesslauer
Evolution of collagen arthritis in mice is arrested by treatment with anti-tumour necrosis factor (TNF) antibody or a recombinant soluble TNF receptor.
Immunology 1992;77(4):510-4.
1992: Georges E Grau; Fabienne Tacchini-Cottier; P F Piguet
Toxoplasmic encephalitis.
Parasitology today (Personal ed.) 1992;8(11):367.
1992: S de Kossodo; Georges E Grau; T Daneva; P Pointaire; L Fossati; C Ody; J Zapf; Pierre-François Piguet; R C Gaillard; P Vassalli
Tumor necrosis factor alpha is involved in mouse growth and lymphoid tissue development.
The Journal of experimental medicine 1992;176(5):1259-64.
1992: Michel Chofflon; C Juillard; P Juillard; G Gauthier; Georges E Grau
Tumor necrosis factor alpha production as a possible predictor of relapse in patients with multiple sclerosis.
European cytokine network 1992;3(6):523-31.
1992: Georges E Grau; F Tacchini-Cooler; P F Piguet
Is TNF beneficial or deleterious in toxoplasmic encephalitis?
Parasitology today (Personal ed.) 1992;8(10):322-4; discussion 335-6.
1992: M P Gascon; HC Porchet; J Y Le Cotonnec; A Ythier; David Wallach; P F Piguet; Georges E Grau
Pharmacokinetics and tissue distribution of human urinary tumor necrosis factor binding protein in mice.
Drug metabolism and disposition: the biological fate of chemicals 1992;20(4):592-5.
1992: P Vassalli; Georges E Grau; Pierre-François Piguet
TNF in autoimmune diseases, graft-versus-host reactions, and pulmonary fibrosis.
Immunology series 1992;56():409-30.
1992: Georges E Grau
Essential role of tumor necrosis factor and other cytokines in the pathogenesis of cerebral malaria: experimental and clinical studies.
Verhandelingen - Koninklijke Academie voor Geneeskunde van België 1992;54(2):155-75.
1992: Georges E Grau; Pierre-François Piguet; Paul-Henri Lambert
Immunopathology of malaria: role of cytokine production and adhesion molecules.
Memórias do Instituto Oswaldo Cruz 1992;87 Suppl 5():95-100.
1991: W Lesslauer; H Tabuchi; R Gentz; Manfred Brockhaus; E J Schlaeger; Georges E Grau; Pierre-François Piguet; P Pointaire; P Vassalli; Hansruedi Loetscher
Recombinant soluble tumor necrosis factor receptor proteins protect mice from lipopolysaccharide-induced lethality.
European journal of immunology 1991;21(11):2883-6.
1991: Georges E Grau; P Pointaire; Pierre-François Piguet; Christian Vesin; H Rosen; I Stamenkovic; F Takei; P Vassalli
Late administration of monoclonal antibody to leukocyte function-antigen 1 abrogates incipient murine cerebral malaria.
European journal of immunology 1991;21(9):2265-7.
1991: Georges E Grau; Christian Vesin; D De Groote; D Delacroix; C Gysler; Pierre-François Piguet; Paul-Henri Lambert
Prevention of human TNF-induced cutaneous Shwartzmann reaction and acute mortality in mice treated with anti-human TNF monoclonal antibodies.
Clinical and experimental immunology 1991;84(3):411-4.
1991: Pierre-François Piguet; Georges E Grau; Conrad Hauser; P Vassalli
Tumor necrosis factor is a critical mediator in hapten induced irritant and contact hypersensitivity reactions.
The Journal of experimental medicine 1991;173(3):673-9.
1991: Pierre-François Piguet; Georges E Grau; P Vassalli
Tumor necrosis factor and immunopathology.
Immunologic research 1991;10(2):122-40.
1990: Georges E Grau; K Frei; Pierre-François Piguet; A Fontana; H Heremans; A Billiau; P Vassalli; Paul-Henri Lambert
Interleukin 6 production in experimental cerebral malaria: modulation by anticytokine antibodies and possible role in hypergammaglobulinemia.
The Journal of experimental medicine 1990;172(5):1505-8.
1990: Georges E Grau
Implications of cytokines in immunopathology: experimental and clinical data.
European cytokine network 1990;1(4):203-10.
1990: Georges E Grau; G Bieler; P Pointaire; S De Kossodo; F Tacchini-Cotier; P Vassalli; Pierre-François Piguet; Paul-Henri Lambert
Significance of cytokine production and adhesion molecules in malarial immunopathology.
Immunology letters 1990;25(1-3):189-94.
1990: Pierre-François Piguet; M A Collart; Georges E Grau; A P Sappino; P Vassalli
Requirement of tumour necrosis factor for development of silica-induced pulmonary fibrosis.
Nature 1990;344(6263):245-7.
1990: Georges E Grau; Paul-Henri Lambert
Retroviral antigen expression on megakaryocytes and platelets: possible implications in the pathogenesis of thrombocytopenia.
Progress in clinical and biological research 1990;356():275-86.
1990: H R Chang; Georges E Grau; Jean-Claude Pechère
Role of TNF and IL-1 in infections with Toxoplasma gondii.
Immunology 1990;69(1):33-7.
1989: Georges E Grau; Paul-Henri Lambert; P Vassalli; Pierre-François Piguet
[Tumor necrosis factor (TNF) and pathology; its relationships with other cytokines].
Schweizerische medizinische Wochenschrift 1989;119(49):1756-61.
1989: Georges E Grau; Pierre-François Piguet; P Vassalli; Paul-Henri Lambert
Tumor-necrosis factor and other cytokines in cerebral malaria: experimental and clinical data.
Immunological reviews 1989;112():49-70.
1989: Georges E Grau; P Roux-Lombard; C Gysler; C Lambert; Paul-Henri Lambert; Jean-Michel Dayer; L Guillevin
Serum cytokine changes in systemic vasculitis.
Immunology 1989;68(2):196-8.
1989: J Merino; H Y Qin; S Schurmans; D Gretener; Georges E Grau; Paul-Henri Lambert
Thrombocytopenia associated with the induction of neonatal tolerance to alloantigens: immunopathogenic mechanisms.
European journal of immunology 1989;19(9):1693-9.
1989: Pierre-François Piguet; M A Collart; Georges E Grau; Y Kapanci; P Vassalli
Tumor necrosis factor/cachectin plays a key role in bleomycin-induced pneumopathy and fibrosis.
The Journal of experimental medicine 1989;170(3):655-63.
1989: Pierre-François Piguet; Georges E Grau; M A Collart; P Vassalli; Y Kapanci
Pneumopathies of the graft-versus-host reaction. Alveolitis associated with an increased level of tumor necrosis factor mRNA and chronic interstitial pneumonitis.
Laboratory investigation; a journal of technical methods and pathology 1989;61(1):37-45.
1989: Georges E Grau; H Heremans; Pierre-François Piguet; P Pointaire; Paul-Henri Lambert; A Billiau; P Vassalli
Monoclonal antibody against interferon gamma can prevent experimental cerebral malaria and its associated overproduction of tumor necrosis factor.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(14):5572-4.
1989: V Kindler; A P Sappino; Georges E Grau; Pierre-François Piguet; P Vassalli
The inducing role of tumor necrosis factor in the development of bactericidal granulomas during BCG infection.
Cell 1989;56(5):731-40.
1989: Georges E Grau; Pierre-François Piguet; P Vassalli; Paul-Henri Lambert
Involvement of tumour necrosis factor and other cytokines in immune-mediated vascular pathology.
International archives of allergy and applied immunology 1989;88(1-2):34-9.
1988: Georges E Grau; Pierre-François Piguet; D Gretener; Christian Vesin; Paul-Henri Lambert
Immunopathology of thrombocytopenia in experimental malaria.
Immunology 1988;65(4):501-6.
1988: Georges E Grau; V Kindler; Pierre-François Piguet; P H Lambert; P Vassalli
Prevention of experimental cerebral malaria by anticytokine antibodies. Interleukin 3 and granulocyte macrophage colony-stimulating factor are intermediates in increased tumor necrosis factor production and macrophage accumulation.
The Journal of experimental medicine 1988;168(4):1499-504.
1987: Pierre-François Piguet; Georges E Grau; B Allet; P Vassalli
Tumor necrosis factor/cachectin is an effector of skin and gut lesions of the acute phase of graft-vs.-host disease.
The Journal of experimental medicine 1987;166(5):1280-9.
1987: Georges E Grau; D Gretener; Paul-Henri Lambert
Prevention of murine cerebral malaria by low-dose cyclosporin A.
Immunology 1987;61(4):521-5.