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Lee Graves

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Lee M Graves; James S Duncan; Martin C Whittle; Gary L Johnson
The dynamic nature of the kinome.
James S Duncan; H Shelton Earp; Stephen V Frye; Shawn M Gomez; Deborah A Granger; Lee M Graves; Xiaping He; Katherine A Hoadley; Jian Jin; Nancy L Johnson; Nicole Vincent Jordan; William Y Kim; Pei-Fen Kuan; Ben Major; Alicia A Midland; Kazuhiro Nakamura; Charles M Perou; Norman E Sharpless; David M Smalley; Jerry Usary; Martin C Whittle; Jon S Zawistowski; Bing Zhou; Amy N Abell; Xin Chen; David B Darr; Gary L Johnson
Dynamic reprogramming of the kinome in response to targeted MEK inhibition in triple-negative breast cancer.
Alicia A Midland; Kazuhiro Nakamura; Martin C Whittle; Jon S Zawistowski; H Shelton Earp; Amy N Abell; Lisa A Carey; James S Duncan; Shawn M Gomez; Lee M Graves; Gary L Johnson
Defining the expressed breast cancer kinome.

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All Publications

2013: Lee M Graves; James S Duncan; Martin C Whittle; Gary L Johnson
The dynamic nature of the kinome.
The Biochemical journal 2013;450(1):1-8.
2012: James S Duncan; H Shelton Earp; Stephen V Frye; Shawn M Gomez; Deborah A Granger; Lee M Graves; Xiaping He; Katherine A Hoadley; Jian Jin; Nancy L Johnson; Nicole Vincent Jordan; William Y Kim; Pei-Fen Kuan; Ben Major; Alicia A Midland; Kazuhiro Nakamura; Charles M Perou; Norman E Sharpless; David M Smalley; Jerry Usary; Martin C Whittle; Jon S Zawistowski; Bing Zhou; Amy N Abell; Xin Chen; David B Darr; Gary L Johnson
Dynamic reprogramming of the kinome in response to targeted MEK inhibition in triple-negative breast cancer.
Cell 2012;149(2):307-21.
2012: Alicia A Midland; Kazuhiro Nakamura; Martin C Whittle; Jon S Zawistowski; H Shelton Earp; Amy N Abell; Lisa A Carey; James S Duncan; Shawn M Gomez; Lee M Graves; Gary L Johnson
Defining the expressed breast cancer kinome.
Cell research 2012;22(4):620-3.
2011: Quyen L Aoh; Lee M Graves; Mara C Duncan
Glucose regulates clathrin adaptors at the trans-Golgi network and endosomes.
Molecular biology of the cell 2011;22(19):3671-83.
2011: Akash Gulyani; Richard Allen; Brian Dewar; Timothy C Elston; Lee M Graves; Dmitriy Gremyachinskiy; Brian Kay; Brian Kuhlman; Steven Lewis; Eric Vitriol; Jianrong Wu; Klaus M Hahn
A biosensor generated via high-throughput screening quantifies cell edge Src dynamics.
Nature chemical biology 2011;7(7):437-44.
2011: Lee M Graves; David W Litchfield
"Going KiNativ": probing the Native Kinome.
Chemistry & biology 2011;18(6):683-4.
2011: Andrea V Leisewitz; Eric I Zimmerman; Min Huang; Shannon Z Jones; Jing Yang; Lee M Graves
Regulation of ENT1 expression and ENT1-dependent nucleoside transport by c-Jun N-terminal kinase.
Biochemical and biophysical research communications 2011;404(1):370-5.
2011: Adriana Beltran Lopez; Lee M Graves; John P Hunt; Haili Quian; Bryan T Richardson; Ashley G Rivenbark; Xinni Yuan; Eric Zimmerman; Pilar Blancafort
Generation of tumor-initiating cells by exogenous delivery of OCT4 transcription factor.
Breast cancer research : BCR 2011;13(5):R94.
2010: Eric I Zimmerman; Claudia M Dollins; Melissa Crawford; Steven Grant; Serge P Nana-Sinkam; Kristy L Richards; Scott M Hammond; Lee M Graves
Lyn kinase-dependent regulation of miR181 and myeloid cell leukemia-1 expression: implications for drug resistance in myelogenous leukemia.
Molecular pharmacology 2010;78(5):811-7.
2010: Jamie K Alan; Anastacia Berzat; Brian J Dewar; Lee M Graves; Adrienne D Cox
Regulation of the Rho family small GTPase Wrch-1/RhoU by C-terminal tyrosine phosphorylation requires Src.
Molecular and cellular biology 2010;30(17):4324-38.
2009: Brian M Wiczer; Sandra Lobo; G Luke Machen; Lee M Graves; David A Bernlohr
FATP1 mediates fatty acid-induced activation of AMPK in 3T3-L1 adipocytes.
Biochemical and biophysical research communications 2009;387(2):234-8.
2009: Eric I Zimmerman; Min Huang; Andrea V Leisewitz; Yanhong Wang; Jing Yang; Lee M Graves
Identification of a novel point mutation in ENT1 that confers resistance to Ara-C in human T cell leukemia CCRF-CEM cells.
FEBS letters 2009;583(2):425-9.
2008: Min Huang; Yanhong Wang; Jing-Jin Gu; Jing Yang; Karen Noel; Beverly S Mitchell; Vern L Schramm; Lee M Graves
Determinants of sensitivity of human T-cell leukemia CCRF-CEM cells to immucillin-H.
Leukemia research 2008;32(8):1268-78.
2008: M Murat Koseoglu; Lee M Graves; William F Marzluff
Phosphorylation of threonine 61 by cyclin a/Cdk1 triggers degradation of stem-loop binding protein at the end of S phase.
Molecular and cellular biology 2008;28(14):4469-79.
2008: Yashwanth Radhakrishnan; Laura A Maile; Yan Ling; Lee M Graves; David R Clemmons
Insulin-like growth factor-I stimulates Shc-dependent phosphatidylinositol 3-kinase activation via Grb2-associated p85 in vascular smooth muscle cells.
The Journal of biological chemistry 2008;283(24):16320-31.
2008: M J Higgins; David R Loiselle; T A Haystead; Lee M Graves
Human cytidine triphosphate synthetase 1 interacting proteins.
Nucleosides, nucleotides & nucleic acids 2008;27(6):850-7.
2008: Andrea V Leisewitz; Eric I Zimmerman; Shannon Z Jones; Jing Yang; Lee M Graves
Imatinib-resistant CML cells have low ENT activity but maintain sensitivity to gemcitabine.
Nucleosides, nucleotides & nucleic acids 2008;27(6):779-86.
2008: James S Duncan; Laszlo Gyenis; John Lenehan; Maria Bretner; Lee M Graves; Timothy A Haystead; David W Litchfield
An unbiased evaluation of CK2 inhibitors by chemoproteomics: characterization of inhibitor effects on CK2 and identification of novel inhibitor targets.
Molecular & cellular proteomics : MCP 2008;7(6):1077-88.
2007: Brian J Dewar; Olivia S Gardner; Ching-Shih Chen; Henry Earp; James M Samet; Lee M Graves
Capacitative calcium entry contributes to the differential transactivation of the epidermal growth factor receptor in response to thiazolidinediones.
Molecular pharmacology 2007;72(5):1146-56.
2007: Matthew J Higgins; Paul R Graves; Lee M Graves
Regulation of human cytidine triphosphate synthetase 1 by glycogen synthase kinase 3.
The Journal of biological chemistry 2007;282(40):29493-503.
2007: Marielle E Yohe; Kent L Rossman; Olivia S Gardner; Antoine E Karnoub; Jason T Snyder; Svetlana Gershburg; Lee M Graves; Channing J Der; John Sondek
Auto-inhibition of the Dbl family protein Tim by an N-terminal helical motif.
The Journal of biological chemistry 2007;282(18):13813-23.
2007: Dongsun Cao; Tamara Tal; Lee M Graves; Ian Gilmour; William Linak; William Reed; Philip A Bromberg; James M Samet
Diesel exhaust particulate-induced activation of Stat3 requires activities of EGFR and Src in airway epithelial cells.
American journal of physiology. Lung cellular and molecular physiology 2007;292(2):L422-9.
2006: Amelia Smyk; Magdalena Szuminska; Katarzyna A Uniewicz; Lee M Graves; Piotr Kozlowski
Human enhancer of rudimentary is a molecular partner of PDIP46/SKAR, a protein interacting with DNA polymerase delta and S6K1 and regulating cell growth.
The FEBS journal 2006;273(20):4728-41.
2006: Jon Rhoads; Xiaomei Niu; Jack Odle; Lee M Graves
Role of mTOR signaling in intestinal cell migration.
American journal of physiology. Gastrointestinal and liver physiology 2006;291(3):G510-7.
2006: Tamara Tal; Lee M Graves; Robert Silbajoris; Philip A Bromberg; Weidong Wu; James M Samet
Inhibition of protein tyrosine phosphatase activity mediates epidermal growth factor receptor signaling in human airway epithelial cells exposed to Zn2+.
Toxicology and applied pharmacology 2006;214(1):16-23.
2006: Yu-Mee Kim; William Reed; Weidong Wu; Philip A Bromberg; Lee M Graves; James M Samet
Zn2+-induced IL-8 expression involves AP-1, JNK, and ERK activities in human airway epithelial cells.
American journal of physiology. Lung cellular and molecular physiology 2006;290(5):L1028-35.
2006: Ian C Davis; Eduardo R Lazarowski; Judy M Hickman-Davis; James A Fortenberry; Fu-Ping Chen; Xiaodong Zhao; Eric J Sorscher; Lee M Graves; Wayne M Sullender; Sadis Matalon
Leflunomide prevents alveolar fluid clearance inhibition by respiratory syncytial virus.
American journal of respiratory and critical care medicine 2006;173(6):673-82.
2005: Thomas L Hilder; Lisa A Baer; Patrick M Fuller; Charles A Fuller; Richard E Grindeland; Charles E Wade; Lee M Graves
Insulin-independent pathways mediating glucose uptake in hindlimb-suspended skeletal muscle.
Journal of applied physiology (Bethesda, Md. : 1985) 2005;99(6):2181-8.
2005: Weidong Wu; Robert Silbajoris; Young E Whang; Lee M Graves; Philip A Bromberg; James M Samet
p38 and EGF receptor kinase-mediated activation of the phosphatidylinositol 3-kinase/Akt pathway is required for Zn2+-induced cyclooxygenase-2 expression.
American journal of physiology. Lung cellular and molecular physiology 2005;289(5):L883-9.
2005: Olivia S Gardner; Brian J Dewar; Lee M Graves
Activation of mitogen-activated protein kinases by peroxisome proliferator-activated receptor ligands: an example of nongenomic signaling.
Molecular pharmacology 2005;68(4):933-41.
2005: Thomas L Hilder; Gerald M Carlson; Timothy A J Haystead; Edwin G Krebs; Lee M Graves
Caspase-3 dependent cleavage and activation of skeletal muscle phosphorylase b kinase.
Molecular and cellular biochemistry 2005;275(1-2):233-42.
2005: Gary L Johnson; Henrik G Dohlman; Lee M Graves
MAPK kinase kinases (MKKKs) as a target class for small-molecule inhibition to modulate signaling networks and gene expression.
Current opinion in chemical biology 2005;9(3):325-31.
2005: Olivia S Gardner; Chung-Wai Shiau; Ching-Shih Chen; Lee M Graves
Peroxisome proliferator-activated receptor gamma-independent activation of p38 MAPK by thiazolidinediones involves calcium/calmodulin-dependent protein kinase II and protein kinase R: correlation with endoplasmic reticulum stress.
The Journal of biological chemistry 2005;280(11):10109-18.
2004: Min Huang; Y Wang; M Collins; Lee M Graves
CPEC induces erythroid differentiation of human myeloid leukemia K562 cells through CTP depletion and p38 MAP kinase.
Leukemia 2004;18(11):1857-63.
2004: Min Huang; Yanhong Wang; Beverly S Mitchell; Lee M Graves
Regulation of equilibrative nucleoside uptake by protein kinase inhibitors.
Nucleosides, nucleotides & nucleic acids 2004;23(8-9):1445-50.
2004: Weidong Wu; James M Samet; Robert Silbajoris; Lisa A Dailey; Dean Sheppard; Philip A Bromberg; Lee M Graves
Heparin-binding epidermal growth factor cleavage mediates zinc-induced epidermal growth factor receptor phosphorylation.
American journal of respiratory cell and molecular biology 2004;30(4):540-7.
2004: Laura A Lindsey-Boltz; Eric M Wauson; Lee M Graves; Aziz Sancar
The human Rad9 checkpoint protein stimulates the carbamoyl phosphate synthetase activity of the multifunctional protein CAD.
Nucleic acids research 2004;32(15):4524-30.
2003: Olivia S Gardner; Brian J Dewar; Henry Earp; James M Samet; Lee M Graves
Dependence of peroxisome proliferator-activated receptor ligand-induced mitogen-activated protein kinase signaling on epidermal growth factor receptor transactivation.
The Journal of biological chemistry 2003;278(47):46261-9.
2003: Thomas L Hilder; Janet C L Tou; Richard E Grindeland; Charles E Wade; Lee M Graves
Phosphorylation of insulin receptor substrate-1 serine 307 correlates with JNK activity in atrophic skeletal muscle.
FEBS letters 2003;553(1-2):63-7.
2003: James M Samet; Brian J Dewar; Weidong Wu; Lee M Graves
Mechanisms of Zn(2+)-induced signal initiation through the epidermal growth factor receptor.
Toxicology and applied pharmacology 2003;191(1):86-93.
2003: Jing-Jin Gu; Karen Gathy; Lalaine Santiago; Eric Chen; Min Huang; Lee M Graves; Beverly S Mitchell
Induction of apoptosis in IL-3-dependent hematopoietic cell lines by guanine nucleotide depletion.
Blood 2003;101(12):4958-65.
2003: Min Huang; Lee M Graves
De novo synthesis of pyrimidine nucleotides; emerging interfaces with signal transduction pathways.
Cellular and molecular life sciences : CMLS 2003;60(2):321-36.
2003: Min Huang; Yanhong Wang; Susan B Cogut; Beverly S Mitchell; Lee M Graves
Inhibition of nucleoside transport by protein kinase inhibitors.
The Journal of pharmacology and experimental therapeutics 2003;304(2):753-60.
2002: Min Huang; Yanhong Wang; Matthew Collins; Beverly S Mitchell; Lee M Graves
A77 1726 induces differentiation of human myeloid leukemia K562 cells by depletion of intracellular CTP pools.
Molecular pharmacology 2002;62(3):463-72.
2002: Min Huang; Yanhong Wang; Matthew Collins; Jing-Jin Gu; Beverly S Mitchell; Lee M Graves
Inhibition of nucleoside transport by p38 MAPK inhibitors.
The Journal of biological chemistry 2002;277(32):28364-7.
2002: Weidong Wu; Lee M Graves; Gordon N Gill; Sarah J Parsons; James M Samet
Src-dependent phosphorylation of the epidermal growth factor receptor on tyrosine 845 is required for zinc-induced Ras activation.
The Journal of biological chemistry 2002;277(27):24252-7.
2002: Lee M Graves; Jun Han; Henry Earp
Transactivation of the EGF receptor: is the PDGF receptor an unexpected accomplice?
Molecular interventions 2002;2(4):208-12.
2002: Jeffrey P MacKeigan; Debra J Taxman; Deborah Hunter; Henry Earp; Lee M Graves; Jenny P-Y Ting
Inactivation of the antiapoptotic phosphatidylinositol 3-kinase-Akt pathway by the combined treatment of taxol and mitogen-activated protein kinase kinase inhibition.
Clinical cancer research : an official journal of the American Association for Cancer Research 2002;8(7):2091-9.
2002: Weidong Wu; Ilona Jaspers; Wenli Zhang; Lee M Graves; James M Samet
Role of Ras in metal-induced EGF receptor signaling and NF-kappaB activation in human airway epithelial cells.
American journal of physiology. Lung cellular and molecular physiology 2002;282(5):L1040-8.
2002: Min Huang; Piotr Kozlowski; Matthew Collins; Yanhong Wang; Timothy A J Haystead; Lee M Graves
Caspase-dependent cleavage of carbamoyl phosphate synthetase II during apoptosis.
Molecular pharmacology 2002;61(3):569-77.
2002: John M Lambert; Antoine E Karnoub; Lee M Graves; Sharon L Campbell; Channing J Der
Role of MLK3-mediated activation of p70 S6 kinase in Rac1 transformation.
The Journal of biological chemistry 2002;277(7):4770-7.
2001: Andrey Sorokin; P Kozlowski; Lee M Graves; A Philip
Protein-tyrosine kinase Pyk2 mediates endothelin-induced p38 MAPK activation in glomerular mesangial cells.
The Journal of biological chemistry 2001;276(24):21521-8.
2000: M F Sidovar; P Kozlowski; Jung Weon Lee; M A Collins; Y He; Lee M Graves
Phosphorylation of serine 43 is not required for inhibition of c-Raf kinase by the cAMP-dependent protein kinase.
The Journal of biological chemistry 2000;275(37):28688-94.
2000: M Yin; Ivan Rusyn; Robert Schoonhoven; Lee M Graves; Elena V Rusyn; X Li; F Li; Adrienne D Cox; T W Harding; Hartwig Bunzendahl; James A Swenberg; Ronald G Thurman
Inhibition of chronic rejection of aortic allografts by dietary glycine.
Transplantation 2000;69(5):773-80.
2000: Lee M Graves; Hedeel I Guy; P Kozlowski; Min Huang; Eduardo R Lazarowski; Marshall pope; M A Collins; E N Dahlstrand; Henry Earp; David R Evans
Regulation of carbamoyl phosphate synthetase by MAP kinase.
Nature 2000;403(6767):328-32.
2000: Jon Rhoads; Robert A Argenzio; W Chen; Lee M Graves; L L Licato; Anthony T Blikslager; J Smith; John Gatzy Jr; David A Brenner
Glutamine metabolism stimulates intestinal cell MAPKs by a cAMP-inhibitable, Raf-independent mechanism.
Gastroenterology 2000;118(1):90-100.
2000: Robert Stachlewitz; X Li; S Smith; Hartwig Bunzendahl; Lee M Graves; Ronald G Thurman
Glycine inhibits growth of T lymphocytes by an IL-2-independent mechanism.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(1):176-82.
1999: Weidong Wu; Lee M Graves; Ilona Jaspers; Robert B Devlin; William Reed; James M Samet
Activation of the EGF receptor signaling pathway in human airway epithelial cells exposed to metals.
The American journal of physiology 1999;277(5 Pt 1):L924-31.
1999: W Qu; Lee M Graves; Ronald G Thurman
PGE(2) stimulates O(2) uptake in hepatic parenchymal cells: involvement of the cAMP-dependent protein kinase.
The American journal of physiology 1999;277(5 Pt 1):G1048-54.
1999: James M Samet; Robert Silbajoris; Weidong Wu; Lee M Graves
Tyrosine phosphatases as targets in metal-induced signaling in human airway epithelial cells.
American journal of respiratory cell and molecular biology 1999;21(3):357-64.
1999: X Li; R C Dy; William G Cance; Lee M Graves; Henry Earp
Interactions between two cytoskeleton-associated tyrosine kinases: calcium-dependent tyrosine kinase and focal adhesion tyrosine kinase.
The Journal of biological chemistry 1999;274(13):8917-24.
1999: M L Rose; CA Rivera; Blair U Bradford; Lee M Graves; Russell C Cattley; Robert Schoonhoven; James A Swenberg; Ronald G Thurman
Kupffer cell oxidant production is central to the mechanism of peroxisome proliferators.
Carcinogenesis 1999;20(1):27-33.
1998: James M Samet; Lee M Graves; JL Quay; Lisa A Dailey; Robert B Devlin; Andrew J Ghio; Weidong Wu; Philip A Bromberg; William Reed
Activation of MAPKs in human bronchial epithelial cells exposed to metals.
The American journal of physiology 1998;275(3 Pt 1):L551-8.
1998: X Li; Jung Weon Lee; Lee M Graves; Henry Earp
Angiotensin II stimulates ERK via two pathways in epithelial cells: protein kinase C suppresses a G-protein coupled receptor-EGF receptor transactivation pathway.
The EMBO journal 1998;17(9):2574-83.
1998: A E Brinson; Timothy Harding; Pamela Diliberto; Y He; X Li; D Hunter; Brian Herman; Henry Earp; Lee M Graves
Regulation of a calcium-dependent tyrosine kinase in vascular smooth muscle cells by angiotensin II and platelet-derived growth factor. Dependence on calcium and the actin cytoskeleton.
The Journal of biological chemistry 1998;273(3):1711-8.
1997: X Li; H Yu; Lee M Graves; Henry Earp
Protein kinase C and protein kinase A inhibit calcium-dependent but not stress-dependent c-Jun N-terminal kinase activation in rat liver epithelial cells.
The Journal of biological chemistry 1997;272(23):14996-5002.
1997: Li-Wha Wu; H K Yoon; David J Baylink; Lee M Graves; K-H William Lau
Fluoride at mitogenic doses induces a sustained activation of p44mapk, but not p42mapk, in human TE85 osteosarcoma cells.
The Journal of clinical endocrinology and metabolism 1997;82(4):1126-35.
1997: Lee M Graves; Y He; J Lambert; D Hunter; X Li; Henry Earp
An intracellular calcium signal activates p70 but not p90 ribosomal S6 kinase in liver epithelial cells.
The Journal of biological chemistry 1997;272(3):1920-8.
1997: Lee M Graves; Karin E Bornfeldt; Edwin G Krebs
Historical perspectives and new insights involving the MAP kinase cascades.
Advances in second messenger and phosphoprotein research 1997;31():49-62.
1996: H Yu; X Li; G S Marchetto; R Dy; D Hunter; Benjamin F Calvo; Tom Dawson; M Wilm; R J Anderegg; Lee M Graves; Henry Earp
Activation of a novel calcium-dependent protein-tyrosine kinase. Correlation with c-Jun N-terminal kinase but not mitogen-activated protein kinase activation.
The Journal of biological chemistry 1996;271(47):29993-8.
1996: Lee M Graves; J C Lawrence
Insulin, growth factors, and cAMP: antagonism in the signal transduction pathways.
Trends in endocrinology and metabolism: TEM 1996;7(2):43-50.
1996: Lee M Graves; Karin E Bornfeldt; Jaspreet S Sidhu; Gretchen M Argast; Elaine W Raines; Russell Ross; Christina C Leslie; Edwin G Krebs
Platelet-derived growth factor stimulates protein kinase A through a mitogen-activated protein kinase-dependent pathway in human arterial smooth muscle cells.
The Journal of biological chemistry 1996;271(1):505-11.
1995: Henry Earp; W R Huckle; Tom Dawson; X Li; Lee M Graves; R Dy
Angiotensin II activates at least two tyrosine kinases in rat liver epithelial cells. Separation of the major calcium-regulated tyrosine kinase from p125FAK.
The Journal of biological chemistry 1995;270(47):28440-7.
1995: Karin E Bornfeldt; Elaine W Raines; Lee M Graves; M P Skinner; Edwin G Krebs; Russell Ross
Platelet-derived growth factor. Distinct signal transduction pathways associated with migration versus proliferation.
Annals of the New York Academy of Sciences 1995;766():416-30.
1995: Lee M Graves; Karin E Bornfeldt; Gretchen M Argast; Edwin G Krebs; X Kong; Tai-An Lin; John C Lawrence
cAMP- and rapamycin-sensitive regulation of the association of eukaryotic initiation factor 4E and the translational regulator PHAS-I in aortic smooth muscle cells.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(16):7222-6.
1995: Karin E Bornfeldt; Lee M Graves; Elaine W Raines; Y Igarashi; Gary Wayman; S Yamamura; Yutaka Yatomi; Jaspreet S Sidhu; Edwin G Krebs; S Hakomori
Sphingosine-1-phosphate inhibits PDGF-induced chemotaxis of human arterial smooth muscle cells: spatial and temporal modulation of PDGF chemotactic signal transduction.
The Journal of cell biology 1995;130(1):193-206.
1995: W P Schiemann; Lee M Graves; Heinz Baumann; K K Morella; D P Gearing; M D Nielsen; Edwin G Krebs; Neil M Nathanson
Phosphorylation of the human leukemia inhibitory factor (LIF) receptor by mitogen-activated protein kinase and the regulation of LIF receptor function by heterologous receptor activation.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(12):5361-5.
1995: J S Campbell; R Seger; Jonathan D Graves; Lee M Graves; A M Jensen; Edwin G Krebs
The MAP kinase cascade.
Recent progress in hormone research 1995;50():131-59.
1994: Karin E Bornfeldt; Elaine W Raines; T Nakano; Lee M Graves; Edwin G Krebs; Russell Ross
Insulin-like growth factor-I and platelet-derived growth factor-BB induce directed migration of human arterial smooth muscle cells via signaling pathways that are distinct from those of proliferation.
The Journal of clinical investigation 1994;93(3):1266-74.
1994: Lee M Graves; Jennifer Northrop; B C Potts; Edwin G Krebs; David Kimelman
Fibroblast growth factor, but not activin, is a potent activator of mitogen-activated protein kinase in Xenopus explants.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(5):1662-6.
1993: Lee M Graves; Karin E Bornfeldt; Elaine W Raines; B C Potts; S G Macdonald; Russell Ross; Edwin G Krebs
Protein kinase A antagonizes platelet-derived growth factor-induced signaling by mitogen-activated protein kinase in human arterial smooth muscle cells.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(21):10300-4.
1993: Natalie G Ahn; J S Campbell; R Seger; A L Jensen; Lee M Graves; Edwin G Krebs
Metabolic labeling of mitogen-activated protein kinase kinase in A431 cells demonstrates phosphorylation on serine and threonine residues.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(11):5143-7.
1993: Edwin G Krebs; Natalie G Ahn; J S Campbell; Lee M Graves; R Seger; J E Weiel
Regulation of protein serine/threonine kinases by tyrosine kinases.
Advances in second messenger and phosphoprotein research 1993;28():227-36.
1992: R Seger; D Seger; F J Lozeman; Natalie G Ahn; Lee M Graves; J S Campbell; L Ericsson; M Harrylock; A M Jensen; Edwin G Krebs
Human T-cell mitogen-activated protein kinase kinases are related to yeast signal transduction kinases.
The Journal of biological chemistry 1992;267(36):25628-31.
1992: T Iwasaki; Y Uehara; Lee M Graves; N Rachie; Karol Bomsztyk
Herbimycin A blocks IL-1-induced NF-kappa B DNA-binding activity in lymphoid cell lines.
FEBS letters 1992;298(2-3):240-4.
1990: Lee M Graves; Robert L Switzer
Aspartokinase II from Bacillus subtilis is degraded in response to nutrient limitation.
The Journal of biological chemistry 1990;265(25):14947-55.
1990: Lee M Graves; Robert L Switzer
Aspartokinase III, a new isozyme in Bacillus subtilis 168.
Journal of bacteriology 1990;172(1):218-23.
1989: L R Chen; C J Yuan; G Somasekhar; P Wejksnora; J E Peterson; A M Myers; Lee M Graves; Patricia T W Cohen; E F da Cruz e Silva; Donald J Graves
Expression and characterization of the tau subunit of phosphorylase kinase.
Biochemical and biophysical research communications 1989;161(2):746-53.
1988: P C Leung; Lee M Graves; C L Tipton
Characterization of the interaction of ophiobolin A and calmodulin.
The International journal of biochemistry 1988;20(12):1351-9.