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Vladimir Arion

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Andrea Kurzwernhart; Doris Marko; Sanela Martic; Gerhard Mühlgassner; Vladimir B Arion; Simone Bächler; Caroline Bartel; Patrick J Bednarski; Magdalena Buczkowska; Michael A Jakupec; Wolfgang Kandioller; Bernhard K Keppler; Heinz-Bernhard Kraatz; Christian G. Hartinger
Structure-activity relationships of targeted RuII(η6-p-cymene) anticancer complexes with flavonol-derived ligands.
Gerhard Mühlgassner; Wolfgang F Schmid; Vladimir B Arion; Caroline Bartel; Michael A Jakupec; Bernhard K Keppler
Biological activity of ruthenium and osmium arene complexes with modified paullones in human cancer cells.
Werner Ginzinger; Michael A Jakupec; Gerhard Mühlgassner; Vladimir B Arion; Walter Berger; Alexander Egger; Markus Galanski; Bernhard K Keppler
Water-soluble cationic derivatives of indirubin, the active anticancer component from Indigo naturalis.

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All Publications

2012: Andrea Kurzwernhart; Doris Marko; Sanela Martic; Gerhard Mühlgassner; Vladimir B Arion; Simone Bächler; Caroline Bartel; Patrick J Bednarski; Magdalena Buczkowska; Michael A Jakupec; Wolfgang Kandioller; Bernhard K Keppler; Heinz-Bernhard Kraatz; Christian G. Hartinger
Structure-activity relationships of targeted RuII(η6-p-cymene) anticancer complexes with flavonol-derived ligands.
Journal of medicinal chemistry 2012;55(23):10512-22.
2012: Gerhard Mühlgassner; Wolfgang F Schmid; Vladimir B Arion; Caroline Bartel; Michael A Jakupec; Bernhard K Keppler
Biological activity of ruthenium and osmium arene complexes with modified paullones in human cancer cells.
Journal of inorganic biochemistry 2012;116():180-7.
2012: Werner Ginzinger; Michael A Jakupec; Gerhard Mühlgassner; Vladimir B Arion; Walter Berger; Alexander Egger; Markus Galanski; Bernhard K Keppler
Water-soluble cationic derivatives of indirubin, the active anticancer component from Indigo naturalis.
Chemistry & biodiversity 2012;9(10):2175-85.
2012: Vladimir B Arion; Anatolie Dobrov; Simone Göschl; Michael A Jakupec; Bernhard K Keppler; Peter Rapta
Ruthenium- and osmium-arene-based paullones bearing a TEMPO free-radical unit as potential anticancer drugs.
Chemical communications (Cambridge, England) 2012;48(68):8559-61.
2012: Miljan N M Milunovic; Nóra V Nagy; Ghenadie Novitchi; Robert Trondl; Éva A Enyedy; Michael A Jakupec; Bernhard K Keppler; Tamás Kiss; Regina Krachler; Vladimir B Arion
L- and D-proline thiosemicarbazone conjugates: coordination behavior in solution and the effect of copper(II) coordination on their antiproliferative activity.
Inorganic chemistry 2012;51(17):9309-21.
2012: Gabriel E Büchel; Petra Heffeter; Michaela Hejl; Michael A Jakupec; Bernhard K Keppler; Iryna N Stepanenko; Walter Berger; Vladimir B Arion
Osmium(IV) complexes with 1H- and 2H-indazoles: tautomer identity versus spectroscopic properties and antiproliferative activity.
Journal of inorganic biochemistry 2012;113():47-54.
2012: Alfred A Hummer; Michael A Jakupec; Bernhard K Keppler; Wolfram Meyer-Klaucke; Ana Mijovilovich; Paul D Quinn; Vladimir B Arion; Caroline Bartel; Tina Geraki; Annette Rompel
X-ray absorption spectroscopy of an investigational anticancer gallium(III) drug: interaction with serum proteins, elemental distribution pattern, and coordination of the compound in tissue.
Journal of medicinal chemistry 2012;55(11):5601-13.
2012: Andrea Kurzwernhart; Doris Marko; Gerhard Mühlgassner; Robert Trondl; Vladimir B Arion; Simone Bächler; Caroline Bartel; Michael A Jakupec; Wolfgang Kandioller; Bernhard K Keppler; Christian G. Hartinger
Targeting the DNA-topoisomerase complex in a double-strike approach with a topoisomerase inhibiting moiety and covalent DNA binder.
Chemical communications (Cambridge, England) 2012;48(40):4839-41.
2012: Yaroslaw D Lampeka; Sergiu Shova; Yulija L Shuĺga; Liudmyla V Tsymbal; Andrij V Barna; Vladimir B Arion
Catenation control in the two-dimensional coordination polymers based on tritopic carboxylate linkers and azamacrocyclic nickel(II) complexes.
Dalton transactions (Cambridge, England : 2003) 2012;41(14):4118-25.
2012: Werner Ginzinger; Michael A Jakupec; Vladimir B Arion; Walter Berger; Markus Galanski; Gerhard Mühlgassner; Michael Reithofer; Alexander Roller; Bernhard K Keppler
A SAR study of novel antiproliferative ruthenium and osmium complexes with quinoxalinone ligands in human cancer cell lines.
Journal of medicinal chemistry 2012;55(7):3398-413.
2011: Iryna N Stepanenko; Gerhard Mühlgassner; Maria S Novak; Alexander Roller; Vladimir B Arion; Michaela Hejl; Michael A Jakupec; Bernhard K Keppler
Organometallic 3-(1H-benzimidazol-2-yl)-1H-pyrazolo[3,4-b]pyridines as potential anticancer agents.
Inorganic chemistry 2011;50(22):11715-28.
2011: Ana Popović-Bijelić; Vladimir B Arion; Eva A Enyedy; Fahmi Himo; Christian Kowol; Maria E S Lind; Jinghui Luo; Astrid Gräslund
Ribonucleotide reductase inhibition by metal complexes of Triapine (3-aminopyridine-2-carboxaldehyde thiosemicarbazone): a combined experimental and theoretical study.
Journal of inorganic biochemistry 2011;105(11):1422-31.
2011: Kuan-Jen Su; Vladimir B Arion; Jean-Luc Mieusset; Mirjana Pačar; Udo H Brinker
Quest for even higher stabilized foiled carbenes.
The Journal of organic chemistry 2011;76(18):7491-6.
2011: Verena Pichler; Seied M Valiahdi; Vladimir B Arion; Markus Galanski; Michael A Jakupec; Bernhard K Keppler
Mono-carboxylated diaminedichloridoplatinum(IV) complexes--selective synthesis, characterization, and cytotoxicity.
Dalton transactions (Cambridge, England : 2003) 2011;40(32):8187-92.
2011: Gabriel E Büchel; Michaela Hejl; Michael A Jakupec; Bernhard K Keppler; Iryna N Stepanenko; Vladimir B Arion
En route to osmium analogues of KP1019: synthesis, structure, spectroscopic properties and antiproliferative activity of trans-[Os(IV)Cl4(Hazole)2].
Inorganic chemistry 2011;50(16):7690-7.
2011: Lidia S Foteeva; Denis A Trofimov; Olga V Kuznetsova; Christian Kowol; Vladimir B Arion; Bernhard K Keppler; Andrei R Timerbaev
A quantitative structure-activity approach for lipophilicity estimation of antitumor complexes of different metals using microemulsion electrokinetic chromatography.
Journal of pharmaceutical and biomedical analysis 2011;55(3):409-13.
2011: Vladimir B Arion; Peter Rapta; Joshua Telser; Sergiu S Shova; Martin Breza; Karol Luspai; Jozef Kozisek
Syntheses, electronic structures, and EPR/UV-vis-NIR spectroelectrochemistry of nickel(II), copper(II), and zinc(II) complexes with a tetradentate ligand based on S-methylisothiosemicarbazide.
Inorganic chemistry 2011;50(7):2918-31.
2011: Amitava Kundu; Herwig Peterlik; Martin Krssak; Anna K Bytzek; Irena Pashkunova-Martic; Vladimir B Arion; Thomas H Helbich; Bernhard K Keppler
Strategies for the covalent conjugation of a bifunctional chelating agent to albumin: synthesis and characterization of potential MRI contrast agents.
Journal of inorganic biochemistry 2011;105(2):250-5.
2011: Muhammad Hanif; Samuel M Meier; Wolfgang Kandioller; Anna Bytzek; Michaela Hejl; Christian G. Hartinger; Alexey A Nazarov; Vladimir B Arion; Michael A Jakupec; Paul J Dyson; Bernhard K Keppler
From hydrolytically labile to hydrolytically stable Ru(II)-arene anticancer complexes with carbohydrate-derived co-ligands.
Journal of inorganic biochemistry 2011;105(2):224-31.
2010: Michael F Primik; Simone Göschl; Michael A Jakupec; Alexander Roller; Bernhard K Keppler; Vladimir B Arion
Structure-activity relationships of highly cytotoxic copper(II) complexes with modified indolo[3,2-c]quinoline ligands.
Inorganic chemistry 2010;49(23):11084-95.
2010: Kuan-Jen Su; Jean-Luc Mieusset; Vladimir B Arion; Wolfgang Knoll; Lothar Brecker; Udo H Brinker
Efforts toward distorted spiropentanes.
The Journal of organic chemistry 2010;75(21):7494-7.
2010: Muhammad Hanif; Helena Henke; Samuel M Meier; Sanela Martic; Mahmoud Labib; Wolfgang Kandioller; Michael A Jakupec; Vladimir B Arion; Heinz-Bernhard Kraatz; Bernhard K Keppler; Christian G. Hartinger
Is the reactivity of M(II)-arene complexes of 3-hydroxy-2(1H)-pyridones to biomolecules the anticancer activity determining parameter?
Inorganic chemistry 2010;49(17):7953-63.
2010: Muhammad Hanif; Alexey A Nazarov; Christian G. Hartinger; Wolfgang Kandioller; Michael A Jakupec; Vladimir B Arion; Paul J Dyson; Bernhard K Keppler
Osmium(II)--versus ruthenium(II)--arene carbohydrate-based anticancer compounds: similarities and differences.
Dalton transactions (Cambridge, England : 2003) 2010;39(31):7345-52.
2010: Lukas K Filak; Gerhard Mühlgassner; Michael A Jakupec; Petra Heffeter; Walter Berger; Vladimir B Arion; Bernhard K Keppler
Organometallic indolo[3,2-c]quinolines versus indolo[3,2-d]benzazepines: synthesis, structural and spectroscopic characterization, and biological efficacy.
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 2010;15(6):903-18.
2010: Wolfgang Knoll; Jean-Luc Mieusset; Vladimir B Arion; Lothar Brecker; Udo H Brinker
2H-Azirines from a concerted addition of alkylcarbenes to nitrile groups.
Organic letters 2010;12(10):2366-9.
2010: Vesna M Djinovic; Markus Galanski; Vladimir B Arion; Bernhard K Keppler
Synthesis and structures of novel 1-methylcytosinato-bridged (ethylenediamine)platinum(II) and platinum(III) dinuclear complexes.
Dalton transactions (Cambridge, England : 2003) 2010;39(15):3633-43.
2010: Christian Kowol; Robert Trondl; Vladimir B Arion; Michael A Jakupec; Irene Lichtscheidl; Bernhard K Keppler
Fluorescence properties and cellular distribution of the investigational anticancer drug triapine (3-aminopyridine-2-carboxaldehyde thiosemicarbazone) and its zinc(II) complex.
Dalton transactions (Cambridge, England : 2003) 2010;39(3):704-6.
2010: Michael F Primik; Gerhard Mühlgassner; Michael A Jakupec; olivier zava; Paul J Dyson; Vladimir B Arion; Bernhard K Keppler
Highly cytotoxic copper(II) complexes with modified paullone ligands.
Inorganic chemistry 2010;49(1):302-11.
2009: Gabriel E Büchel; Iryna N Stepanenko; Michaela Hejl; Michael A Jakupec; Vladimir B Arion; Bernhard K Keppler
[Os(IV)Cl(5)(Hazole)](-) complexes: synthesis, structure, spectroscopic properties, and antiproliferative activity.
Inorganic chemistry 2009;48(22):10737-47.
2009: Wolfgang Kandioller; Christian G. Hartinger; Alexey A Nazarov; Caroline Bartel; Matthias Skocic; Michael A Jakupec; Vladimir B Arion; Bernhard K Keppler
Maltol-derived ruthenium-cymene complexes with tumor inhibiting properties: the impact of ligand-metal bond stability on anticancer activity in vitro.
Chemistry (Weinheim an der Bergstrasse, Germany) 2009;15(45):12283-91.
2009: Christian Kowol; Robert Trondl; Petra Heffeter; Vladimir B Arion; Michael A Jakupec; Alexander Roller; Markus Galanski; Walter Berger; Bernhard K Keppler
Impact of metal coordination on cytotoxicity of 3-aminopyridine-2-carboxaldehyde thiosemicarbazone (triapine) and novel insights into terminal dimethylation.
Journal of medicinal chemistry 2009;52(16):5032-43.
2009: Gerald Wagner; Vladimir B Arion; Lothar Brecker; Carsten Krantz; Jean-Luc Mieusset; Udo H Brinker
Controllable selective functionalization of a cavitand via solid state photolysis of an encapsulated phenyl azide.
Organic letters 2009;11(14):3056-8.
2009: Marcel Wieland; Kuan-Jen Su; Gerald Wagner; Udo H Brinker; Vladimir B Arion
1,2,4,5-Tetrakis(diazidomethyl)benzene.
Acta crystallographica. Section C, Crystal structure communications 2009;65(Pt 5):o240-2.
2009: Johanna Kasser; Alexey A Nazarov; Christian G. Hartinger; Brigitte Wdziekonski; Christian Dani; Maxim L Kuznetsov; Vladimir B Arion; Bernhard K Keppler
A one step/one pot synthesis of N,N-bis(phosphonomethyl)amino acids and their effects on adipogenic and osteogenic differentiation of human mesenchymal stem cells.
Bioorganic & medicinal chemistry 2009;17(9):3388-93.
2008: Christian Kowol; Erwin Reisner; Ion Chiorescu; Vladimir B Arion; Markus Galanski; Dirk V Deubel; Bernhard K Keppler
An electrochemical study of antineoplastic gallium, iron and ruthenium complexes with redox noninnocent alpha-N-heterocyclic chalcogensemicarbazones.
Inorganic chemistry 2008;47(23):11032-47.
2008: Michael R Reithofer; Seied M Valiahdi; Markus Galanski; Michael A Jakupec; Vladimir B Arion; Bernhard K Keppler
Novel endothall-containing platinum(IV) complexes: synthesis, characterization, and cytotoxic activity.
Chemistry & biodiversity 2008;5(10):2160-70.
2008: Jean-Luc Mieusset; Alexander Bespokoev; Mirjana Pacar; Michael Abraham; Vladimir B Arion; Udo H Brinker
Intermolecular reactions of foiled carbenes with N-H bonds: evidence for an ylidic pathway.
The Journal of organic chemistry 2008;73(17):6551-8.
2008: Iryna N Stepanenko; Artem A Krokhin; Roland O John; Alexander Roller; Vladimir B Arion; Michael A Jakupec; Bernhard K Keppler
Synthesis, structure, spectroscopic properties, and antiproliferative activity in vitro of novel osmium(III) complexes with azole heterocycles.
Inorganic chemistry 2008;47(16):7338-47.
2008: Alexander Egger; Berta Cebrián-Losantos; Iryna N Stepanenko; Artem A Krokhin; Rene Eichinger; Michael A Jakupec; Vladimir B Arion; Bernhard K Keppler
Hydrolysis and cytotoxic properties of osmium(II)/(III)-DMSO-azole complexes. Short communication.
Chemistry & biodiversity 2008;5(8):1588-93.
2008: Berta Cebrián-Losantos; Erwin Reisner; Christian Kowol; Alexander Roller; Sergiu Shova; Vladimir B Arion; Bernhard K Keppler
Synthesis and reactivity of the aquation product of the antitumor complex trans-[Ru(III)Cl4(indazole)2]-.
Inorganic chemistry 2008;47(14):6513-23.
2008: Michael R Reithofer; Markus Galanski; Vladimir B Arion; Bernhard K Keppler
Unprecedented twofold intramolecular hydroamination in diam(m)ine-dicarboxylatodichloridoplatinum(IV) complexes - ethane-1,2-diamine vs. ammine ligands.
Chemical communications (Cambridge, England) 2008;(9):1091-3.
2008: Michael A Jakupec; Markus Galanski; Vladimir B Arion; Christian G. Hartinger; Bernhard K Keppler
Antitumour metal compounds: more than theme and variations.
Dalton transactions (Cambridge, England : 2003) 2008;(2):183-94.
2008: Isabella Berger; Muhammad Hanif; Alexey A Nazarov; Christian G. Hartinger; Roland O John; Maxim L Kuznetsov; Michael Groessl; Frederic Schmitt; olivier zava; Florian Biba; Vladimir B Arion; Markus Galanski; Michael A Jakupec; Lucienne Juillerat-Jeanneret; Paul J Dyson; Bernhard K Keppler
In vitro anticancer activity and biologically relevant metabolization of organometallic ruthenium complexes with carbohydrate-based ligands.
Chemistry (Weinheim an der Bergstrasse, Germany) 2008;14(29):9046-57.
2007: Michael R Reithofer; Seied M Valiahdi; Michael A Jakupec; Vladimir B Arion; Alexander Egger; Markus Galanski; Bernhard K Keppler
Novel di- and tetracarboxylatoplatinum(IV) complexes. Synthesis, characterization, cytotoxic activity, and DNA platination.
Journal of medicinal chemistry 2007;50(26):6692-9.
2007: Walther Schmid; Roland O John; Gerhard Mühlgassner; Petra Heffeter; Michael A Jakupec; Markus Galanski; Walter Berger; Vladimir B Arion; Bernhard K Keppler
Metal-based paullones as putative CDK inhibitors for antitumor chemotherapy.
Journal of medicinal chemistry 2007;50(25):6343-55.
2007: Christian Kowol; Rene Eichinger; Michael A Jakupec; Markus Galanski; Vladimir B Arion; Bernhard K Keppler
Effect of metal ion complexation and chalcogen donor identity on the antiproliferative activity of 2-acetylpyridine N,N-dimethyl(chalcogen)semicarbazones.
Journal of inorganic biochemistry 2007;101(11-12):1946-57.
2007: Vladimir O Gelmboldt; Eduard V Ganin; Marina S Fonari; Yurii A Simonov; Larisa V Koroeva; Alim A Ennan; Stepan S Basok; Sergiu Shova; Hanspeter Kählig; Vladimir B Arion; Bernhard K Keppler
Two new "onium" fluorosilicates, the products of interaction of fluorosilicic acid with 12-membered macrocycles: structures and spectroscopic properties.
Dalton transactions (Cambridge, England : 2003) 2007;(27):2915-24.
2007: Berta Cebrián-Losantos; Artem A Krokhin; Iryna N Stepanenko; Rene Eichinger; Michael A Jakupec; Vladimir B Arion; Bernhard K Keppler
Osmium NAMI-A analogues: synthesis, structural and spectroscopic characterization, and antiproliferative properties.
Inorganic chemistry 2007;46(12):5023-33.
2007: Michael Groessl; Erwin Reisner; Christian G. Hartinger; Rene Eichinger; Olga Semenova; Andrei R Timerbaev; Michael A Jakupec; Vladimir B Arion; Bernhard K Keppler
Structure-activity relationships for NAMI-A-type complexes (HL)[trans-RuCl4L(S-dmso)ruthenate(III)] (L = imidazole, indazole, 1,2,4-triazole, 4-amino-1,2,4-triazole, and 1-methyl-1,2,4-triazole): aquation, redox properties, protein binding, and antiproliferative activity.
Journal of medicinal chemistry 2007;50(9):2185-93.
2007: Walther Schmid; Stefanie Zorbas-Seifried; Roland O John; Vladimir B Arion; Michael A Jakupec; Alexander Roller; Markus Galanski; Ion Chiorescu; Haralabos Zorbas; Bernhard K Keppler
The first ruthenium-based paullones: syntheses, X-ray diffraction structures, and spectroscopic and antiproliferative properties in vitro.
Inorganic chemistry 2007;46(9):3645-56.
2007: Christian Kowol; Roland Berger; Rene Eichinger; Alexander Roller; Michael A Jakupec; Peter P Schmidt; Vladimir B Arion; Bernhard K Keppler
Gallium(III) and iron(III) complexes of alpha-N-heterocyclic thiosemicarbazones: synthesis, characterization, cytotoxicity, and interaction with ribonucleotide reductase.
Journal of medicinal chemistry 2007;50(6):1254-65.
2007: Kuan-Jen Su; Jean-Luc Mieusset; Vladimir B Arion; Lothar Brecker; Udo H Brinker
Cope rearrangement versus a novel tandem retro-Diels-Alder-Diels-Alder reaction with role reversal.
Organic letters 2007;9(1):113-5.
2007: Konrad Tiefenbacher; Vladimir B Arion; Johann Mulzer
A Diels-Alder approach to (-)-ovalicin.
Angewandte Chemie (International ed. in English) 2007;46(15):2690-3.
2006: Alexander V Rudnev; Lidia S Foteeva; Christian Kowol; Roland Berger; Michael A Jakupec; Vladimir B Arion; Andrei R Timerbaev; Bernhard K Keppler
Preclinical characterization of anticancer gallium(III) complexes: solubility, stability, lipophilicity and binding to serum proteins.
Journal of inorganic biochemistry 2006;100(11):1819-26.
2006: Wolfgang Felzmann; Vladimir B Arion; Jean-Luc Mieusset; Johann Mulzer
A tether controlled exo-selective trans-annular Diels-Alder (TADA) reaction.
Organic letters 2006;8(17):3849-51.
2006: Günter Trettenhahn; Michael Nagl; Norbert Neuwirth; Vladimir B Arion; Walther Jary; Peter Pöchlauer; Walther Schmid
A hexanuclear iron(III) carboxylate with an [Fe6(mu3-O)3(mu2-OH)]11+ core as an efficient catalyst for cycloalkane oxidation.
Angewandte Chemie (International ed. in English) 2006;45(17):2794-8.
2006: Peter Walla; Vladimir B Arion; Udo H Brinker
Solvent- and temperature-tuned orientation of ferrocenyl azide inside beta-cyclodextrin.
The Journal of organic chemistry 2006;71(8):3274-7.
2006: Anatoly Dobrov; Vladimir B Arion; Norbert Kandler; Werner Ginzinger; Michael A Jakupec; Anna Rufińska; Nikolai Graf von Keyserlingk; Markus Galanski; Christian Kowol; Bernhard K Keppler
The first metal-based paullone derivative with high antiproliferative activity in vitro.
Inorganic chemistry 2006;45(5):1945-50.
2005: Diana Dragancea; Vladimir B Arion; Sergiu Shova; Eva Rentschler; Nicolae V Gerbeleu
Azine-bridged octanuclear copper(II) complexes assembled with a one-stranded ditopic thiocarbohydrazone ligand.
Angewandte Chemie (International ed. in English) 2005;44(48):7938-42.
2005: Michael A Jakupec; Vladimir B Arion; Susanne Kapitza; Erwin Reisner; Anna Eichinger; Martina Pongratz; Brigitte Marian; Nikolai Graf von Keyserlingk; Bernhard K Keppler
KP1019 (FFC14A) from bench to bedside: preclinical and early clinical development--an overview.
International journal of clinical pharmacology and therapeutics 2005;43(12):595-6.
2005: Erwin Reisner; Vladimir B Arion; Anna Eichinger; Norbert Kandler; Gerald Giester; Armando J L Pombeiro; Bernhard K Keppler
Tuning of redox properties for the design of ruthenium anticancer drugs: part 2. Syntheses, crystal structures, and electrochemistry of potentially antitumor [Ru III/II Cl6-n(Azole)n]z(n = 3, 4, 6) complexes.
Inorganic chemistry 2005;44(19):6704-16.
2005: Erwin Reisner; Vladimir B Arion; Anna Rufińska; Ion Chiorescu; Walther Schmid; Bernhard K Keppler
Isomeric [RuCl2(dmso)2(indazole)2] complexes: ruthenium(II)-mediated coupling reaction of acetonitrile with 1H-indazole.
Dalton transactions (Cambridge, England : 2003) 2005;(14):2355-64.
2005: Michael A Jakupec; Erwin Reisner; Anna Eichinger; Martina Pongratz; Vladimir B Arion; Markus Galanski; Christian G. Hartinger; Bernhard K Keppler
Redox-active antineoplastic ruthenium complexes with indazole: correlation of in vitro potency and reduction potential.
Journal of medicinal chemistry 2005;48(8):2831-7.
2005: Alexander Egger; Vladimir B Arion; Erwin Reisner; Berta Cebrián-Losantos; Sergiu Shova; Günter Trettenhahn; Bernhard K Keppler
Reactions of potent antitumor complex trans-[Ru(III)Cl4(indazole)2]- with a DNA-relevant nucleobase and thioethers: insight into biological action.
Inorganic chemistry 2005;44(1):122-32.
2004: Erwin Reisner; Vladimir B Arion; M Fátima C Guedes da Silva; Roman Lichtenecker; Anna Eichinger; Bernhard K Keppler; Vadim Yu Kukushkin; Armando J L Pombeiro
Tuning of redox potentials for the design of ruthenium anticancer drugs -- an electrochemical study of [trans-RuCl(4)L(DMSO)](-) and [trans-RuCl(4)L(2)](-) complexes, where L = imidazole, 1,2,4-triazole, indazole.
Inorganic chemistry 2004;43(22):7083-93.
2004: Markus Galanski; Afshin Yasemi; Susanna Slaby; Michael A Jakupec; Vladimir B Arion; Monika Rausch; Alexey A Nazarov; Bernhard K Keppler
Synthesis, crystal structure and cytotoxicity of new oxaliplatin analogues indicating that improvement of anticancer activity is still possible.
European journal of medicinal chemistry 2004;39(8):707-14.
2003: Vladimir B Arion; Erwin Reisner; Madeleine Fremuth; Michael A Jakupec; Bernhard K Keppler; Vadim Yu Kukushkin; Armando J L Pombeiro
Synthesis, X-ray diffraction structures, spectroscopic properties, and in vitro antitumor activity of isomeric (1H-1,2,4-triazole)Ru(III) complexes.
Inorganic chemistry 2003;42(19):6024-31.
2003: M Galanski; Vladimir B Arion; Michael A Jakupec; Bernhard K Keppler
Recent developments in the field of tumor-inhibiting metal complexes.
Current pharmaceutical design 2003;9(25):2078-89.
2002: Vladimir B Arion; Michael A Jakupec; Markus Galanski; Peter Unfried; Bernhard K Keppler
Synthesis, structure, spectroscopic and in vitro antitumour studies of a novel gallium(III) complex with 2-acetylpyridine (4)N-dimethylthiosemicarbazone.
Journal of inorganic biochemistry 2002;91(1):298-305.