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John Gray

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John A Gray; Beth A Compton-Toth; Bryan L Roth
Identification of two serine residues essential for agonist-induced 5-HT2A receptor desensitization.
Zongqi Xia; John A Gray; Beth A Compton-Toth; Bryan L Roth
A direct interaction of PSD-95 with 5-HT2A serotonin receptors regulates receptor trafficking and signal transduction.
John A Gray; Anushree Bhatnagar; Vsevolod V Gurevich; Bryan L Roth
The interaction of a constitutively active arrestin with the arrestin-insensitive 5-HT(2A) receptor induces agonist-independent internalization.

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All Publications

2003: John A Gray; Beth A Compton-Toth; Bryan L Roth
Identification of two serine residues essential for agonist-induced 5-HT2A receptor desensitization.
Biochemistry 2003;42(36):10853-62.
2003: Zongqi Xia; John A Gray; Beth A Compton-Toth; Bryan L Roth
A direct interaction of PSD-95 with 5-HT2A serotonin receptors regulates receptor trafficking and signal transduction.
The Journal of biological chemistry 2003;278(24):21901-8.
2003: John A Gray; Anushree Bhatnagar; Vsevolod V Gurevich; Bryan L Roth
The interaction of a constitutively active arrestin with the arrestin-insensitive 5-HT(2A) receptor induces agonist-independent internalization.
Molecular pharmacology 2003;63(5):961-72.
2003: Zongqi Xia; Sandra J Hufeisen; John A Gray; Bryan L Roth
The PDZ-binding domain is essential for the dendritic targeting of 5-HT2A serotonin receptors in cortical pyramidal neurons in vitro.
Neuroscience 2003;122(4):907-20.
2002: John A Gray; Bryan L Roth
Cell biology. A last GASP for GPCRs?
Science (New York, N.Y.) 2002;297(5581):529-31.
2001: John A Gray; Bryan L Roth
Paradoxical trafficking and regulation of 5-HT(2A) receptors by agonists and antagonists.
Brain research bulletin 2001;56(5):441-51.
2001: John A Gray; Douglas J Sheffler; Anushree Bhatnagar; J A Woods; Sandra J Hufeisen; JL Benovic; Bryan L Roth
Cell-type specific effects of endocytosis inhibitors on 5-hydroxytryptamine(2A) receptor desensitization and resensitization reveal an arrestin-, GRK2-, and GRK5-independent mode of regulation in human embryonic kidney 293 cells.
Molecular pharmacology 2001;60(5):1020-30.
2001: Anushree Bhatnagar; DL Willins; John A Gray; J Woods; JL Benovic; Bryan L Roth
The dynamin-dependent, arrestin-independent internalization of 5-hydroxytryptamine 2A (5-HT2A) serotonin receptors reveals differential sorting of arrestins and 5-HT2A receptors during endocytosis.
The Journal of biological chemistry 2001;276(11):8269-77.
1999: E I Gelber; Wesley K Kroeze; DL Willins; John A Gray; C A Sinar; E G Hyde; Vsevolod V Gurevich; JL Benovic; Bryan L Roth
Structure and function of the third intracellular loop of the 5-hydroxytryptamine2A receptor: the third intracellular loop is alpha-helical and binds purified arrestins.
Journal of neurochemistry 1999;72(5):2206-14.