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Lloyd Gray

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Nicholas C K Valerie; Lloyd S Gray; Amol S Hosing; James M Larner; Ewa Augustin; David L Brautigan; Barbara Dziegielewska; Jaroslaw Dziegielewski
Inhibition of T-type calcium channels disrupts Akt signaling and promotes apoptosis in glioblastoma cells.
Lloyd S Gray; Timothy L MacDonald
The pharmacology and regulation of T type calcium channels: new opportunities for unique therapeutics for cancer.
William F McCalmont; Jaclyn R Patterson; Michael A Lindenmuth; Tiffany N Heady; Doris M Haverstick; Lloyd S Gray; Timothy L MacDonald
Investigation into the structure-activity relationship of novel concentration dependent, dual action T-type calcium channel agonists/antagonists.

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All Publications

2013: Nicholas C K Valerie; Lloyd S Gray; Amol S Hosing; James M Larner; Ewa Augustin; David L Brautigan; Barbara Dziegielewska; Jaroslaw Dziegielewski
Inhibition of T-type calcium channels disrupts Akt signaling and promotes apoptosis in glioblastoma cells.
Biochemical pharmacology 2013;85(7):888-97.
2006: Lloyd S Gray; Timothy L MacDonald
The pharmacology and regulation of T type calcium channels: new opportunities for unique therapeutics for cancer.
Cell calcium 2006;40(2):115-20.
2005: William F McCalmont; Jaclyn R Patterson; Michael A Lindenmuth; Tiffany N Heady; Doris M Haverstick; Lloyd S Gray; Timothy L MacDonald
Investigation into the structure-activity relationship of novel concentration dependent, dual action T-type calcium channel agonists/antagonists.
Bioorganic & medicinal chemistry 2005;13(11):3821-39.
2004: Lloyd S Gray; Edward Perez-Reyes; Juan Carlos Gomora; Juan Carlos Gamorra; Doris M Haverstick; Michael Shattock; Linda McLatchie; Jane Harper; Gavin Brooks; Tiffany N Heady; Timothy L MacDonald
The role of voltage gated T-type Ca2+ channel isoforms in mediating "capacitative" Ca2+ entry in cancer cells.
Cell calcium 2004;36(6):489-97.
2004: William F McCalmont; Tiffany N Heady; Jaclyn R Patterson; Michael A Lindenmuth; Doris M Haverstick; Lloyd S Gray; Timothy L MacDonald
Design, synthesis, and biological evaluation of novel T-Type calcium channel antagonists.
Bioorganic & medicinal chemistry letters 2004;14(14):3691-5.
2001: Mary C Gray; Sang-Jin Lee; Lloyd S Gray; F R Zaretzky; AS Otero; Gabor Szabo; Erik L Hewlett
Translocation-specific conformation of adenylate cyclase toxin from Bordetella pertussis inhibits toxin-mediated hemolysis.
Journal of bacteriology 2001;183(20):5904-10.
2000: Doris M Haverstick; Tiffany N Heady; Timothy L MacDonald; Lloyd S Gray
Inhibition of human prostate cancer proliferation in vitro and in a mouse model by a compound synthesized to block Ca2+ entry.
Cancer research 2000;60(4):1002-8.
1998: Doris M Haverstick; John J Densmore; Lloyd S Gray
Calmodulin regulation of Ca2+ entry in Jurkat T cells.
Cell calcium 1998;23(6):361-7.
1997: Doris M Haverstick; M Dicus; MS Resnick; Julianne J Sando; Lloyd S Gray
A role for protein kinase CbetaI in the regulation of Ca2+ entry in Jurkat T cells.
The Journal of biological chemistry 1997;272(24):15426-33.
1996: J J Densmore; Doris M Haverstick; G Szabo; Lloyd S Gray
A voltage-operable current is involved in Ca2+ entry in human lymphocytes whereas ICRAC has no apparent role.
The American journal of physiology 1996;271(5 Pt 1):C1494-503.
1994: K A Sindt; Erik L Hewlett; G T Redpath; R Rappuoli; Lloyd S Gray; Scott R Vandenberg
Pertussis toxin activates platelets through an interaction with platelet glycoprotein Ib.
Infection and immunity 1994;62(8):3108-14.
1993: Richard C Friedberg; S F Donnelly; J C Boyd; Lloyd S Gray; Paul D Mintz
Clinical and blood bank factors in the management of platelet refractoriness and alloimmunization.
Blood 1993;81(12):3428-34.
1993: Doris M Haverstick; Lloyd S Gray
Increased intracellular Ca2+ induces Ca2+ influx in human T lymphocytes.
Molecular biology of the cell 1993;4(2):173-84.
1992: J J Densmore; G Szabo; Lloyd S Gray
A voltage-gated calcium channel is linked to the antigen receptor in Jurkat T lymphocytes.
FEBS letters 1992;312(2-3):161-4.
1992: Doris M Haverstick; Lloyd S Gray
Lymphocyte adhesion mediated by lymphocyte function-associated antigen-1. II. Interaction between phorbol ester- and cAMP-sensitive pathways.
Journal of immunology (Baltimore, Md. : 1950) 1992;149(2):397-402.
1992: Doris M Haverstick; Lloyd S Gray
Lymphocyte adhesion mediated by lymphocyte function-associated antigen-1. I. Long term augmentation by transient increases in intracellular cAMP.
Journal of immunology (Baltimore, Md. : 1950) 1992;149(2):389-96.
1992: Doris M Haverstick; H Sakai; Lloyd S Gray
Lymphocyte adhesion can be regulated by cytoskeleton-associated, PMA-induced capping of surface receptors.
The American journal of physiology 1992;262(4 Pt 1):C916-26.
1991: Doris M Haverstick; Victor H Engelhard; Lloyd S Gray
Three intracellular signals for cytotoxic T lymphocyte-mediated killing. Independent roles for protein kinase C, Ca2+ influx, and Ca2+ release from internal stores.
Journal of immunology (Baltimore, Md. : 1950) 1991;146(10):3306-13.
1991: I E Ehrmann; Mary C Gray; V M Gordon; Lloyd S Gray; Erik L Hewlett
Hemolytic activity of adenylate cyclase toxin from Bordetella pertussis.
FEBS letters 1991;278(1):79-83.
1991: G Anderson; Lloyd S Gray; Paul D Mintz
Red cell survival studies in a patient with anti-Tca.
American journal of clinical pathology 1991;95(1):87-90.
1989: M E May; Paul D Mintz; Lloyd S Gray
Multicompartment analysis of the effects of plasmapheresis. Application to lipid kinetics in humans.
American journal of clinical pathology 1989;91(6):688-94.
1989: Lloyd S Gray; K S Huber; Mary C Gray; Erik L Hewlett; Victor H Engelhard
Pertussis toxin effects on T lymphocytes are mediated through CD3 and not by pertussis toxin catalyzed modification of a G protein.
Journal of immunology (Baltimore, Md. : 1950) 1989;142(5):1631-8.
1988: Lloyd S Gray; J R Gnarra; J A Sullivan; Gerald L Mandell; Victor H Engelhard
Spatial and temporal characteristics of the increase in intracellular Ca2+ induced in cytotoxic T lymphocytes by cellular antigen.
Journal of immunology (Baltimore, Md. : 1950) 1988;141(7):2424-30.
1988: Lloyd S Gray; J Gnarra; Erik L Hewlett; Victor H Engelhard
Increased intracellular cyclic adenosine monophosphate inhibits T lymphocyte-mediated cytolysis by two distinct mechanisms.
The Journal of experimental medicine 1988;167(6):1963-8.
1988: U Wrotnowski; Lloyd S Gray; G Anderson; J E Samsell; Paul D Mintz
Evaluation of adenosine triphosphate and 2,3-diphosphoglycerate after twenty-four hours in red cells washed for neonatal transfusion.
Vox sanguinis 1988;54(2):71-3.
1988: Victor H Engelhard; J R Gnarra; J Sullivan; Gerald L Mandell; Lloyd S Gray
Early events in target-cell lysis by cytotoxic T cells.
Annals of the New York Academy of Sciences 1988;532():303-13.
1987: Lloyd S Gray; J R Gnarra; J H Russell; V H Engelhard
The role of K+ in the regulation of the increase in intracellular Ca2+ mediated by the T lymphocyte antigen receptor.
Cell 1987;50(1):119-27.
1987: Lloyd S Gray; J R Gnarra; Victor H Engelhard
Demonstration of a calcium influx in cytolytic T lymphocytes in response to target cell binding.
Journal of immunology (Baltimore, Md. : 1950) 1987;138(1):63-9.
1986: Lloyd S Gray; J H Russell
Cytolytic T lymphocyte effector function requires plasma membrane chloride flux.
Journal of immunology (Baltimore, Md. : 1950) 1986;136(8):3032-7.