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Anthony Green
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40
Göttgens, Berthold
27
Nacheva, Elisabeth
26
Bench, Anthony
18
Huntly, Brian
16
Begley, Glenn
16
Campbell, Peter
13
Grace, Colin
12
Erber, Wendy
12
SCOTT, Linda
11
Harrison, Claire
10
Kinston, Sarah
10
Piltz, Sandie
10
Bockamp, EO
9
Bareford, David
9
Barton, Linda
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All Publications
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2009: Wood Andrew D; Chen Edwin; Donaldson Ian J; Hattangadi Shilpa; Burke Karly A; Dawson Mark A; Miranda-Saavedra Diego; Lodish Harvey F; Green Anthony R; Göttgens Berthold
ID1 promotes expansion and survival of primary erythroid cells and is a target of JAK2V617F-STAT5 signaling.
Blood 2009;114(9):1820-30.
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2009: Campbell Peter J; Bareford David; Erber Wendy N; Wilkins Bridget S; Wright Penny; Buck Georgina; Wheatley Keith; Harrison Claire N; Green Anthony R
Reticulin accumulation in essential thrombocythemia: prognostic significance and relationship to therapy.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2009;27(18):2991-9.
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2009: Beer Philip A; Jones Amy V; Bench Anthony J; Goday-Fernandez Andrea; Boyd Elaine M; Vaghela Krishna J; Erber Wendy N; Odeh Bassam; Wright Christine; McMullin Mary Frances; Cullis Jonathan; Huntly Brian J P; Harrison Claire N; Cross Nicholas C P; Green Anthony R
Clonal diversity in the myeloproliferative neoplasms: independent origins of genetically distinct clones.
British journal of haematology 2009;144(6):904-8.
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2008: Zhao Rui; Follows George A; Beer Philip A; Scott Linda M; Huntly Brian J P; Green Anthony R; Alexander Denis R
Inhibition of the Bcl-xL deamidation pathway in myeloproliferative disorders.
The New England journal of medicine 2008;359(26):2778-89.
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2008: Fourouclas Nasios; Li Juan; Gilby Daniel C; Campbell Peter J; Beer Philip A; Boyd Elaine M; Goodeve Anne C; Bareford David; Harrison Claire N; Reilly John T; Green Anthony R; Bench Anthony J
Methylation of the suppressor of cytokine signaling 3 gene (SOCS3) in myeloproliferative disorders.
Haematologica 2008;93(11):1635-44.
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2008: Campbell Peter J; Pleasance Erin D; Stephens Philip J; Dicks Ed; Rance Richard; Goodhead Ian; Follows George A; Green Anthony R; Futreal P Andy; Stratton Michael R
Subclonal phylogenetic structures in cancer revealed by ultra-deep sequencing.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(35):13081-6.
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2008: Smith Aileen M; Sanchez Maria-Jose; Follows George A; Kinston Sarah; Donaldson Ian J; Green Anthony R; Göttgens Berthold
A novel mode of enhancer evolution: the Tal1 stem cell enhancer recruited a MIR element to specifically boost its activity.
Genome research 2008;18(9):1422-32.
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2008: Beer Philip A; Campbell Peter J; Scott Linda M; Bench Anthony J; Erber Wendy N; Bareford David; Wilkins Bridget S; Reilly John T; Hasselbalch Hans C; Bowman Richard; Wheatley Keith; Buck Georgina; Harrison Claire N; Green Anthony R
MPL mutations in myeloproliferative disorders: analysis of the PT-1 cohort.
Blood 2008;112(1):141-9.
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2008: Percy Melanie J; Beer Philip A; Campbell Gavin; Dekker Ad W; Green Anthony R; Oscier David; Rainey M Glenn; van Wijk Richard; Wood Marion; Lappin Terence R J; McMullin Mary Frances; Lee Frank S
Novel exon 12 mutations in the HIF2A gene associated with erythrocytosis.
Blood 2008;111(11):5400-2.
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2008: Wilkins Bridget S; Erber Wendy N; Bareford David; Buck Georgina; Wheatley Keith; East Clare L; Paul Beverley; Harrison Claire N; Green Anthony R; Campbell Peter J
Bone marrow pathology in essential thrombocythemia: interobserver reliability and utility for identifying disease subtypes.
Blood 2008;111(1):60-70.
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2007: Percy Melanie J; Scott Linda M; Erber Wendy N; Harrison Claire N; Reilly John T; Jones Frank G C; Green Anthony R; McMullin Mary Frances
The frequency of JAK2 exon 12 mutations in idiopathic erythrocytosis patients with low serum erythropoietin levels.
Haematologica 2007;92(12):1607-14.
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2007: Pimanda John E; Ottersbach Katrin; Knezevic Kathy; Kinston Sarah; Chan Wan Y I; Wilson Nicola K; Landry Josette-Renée; Wood Andrew D; Kolb-Kokocinski Anja; Green Anthony R; Tannahill David; Lacaud Georges; Kouskoff Valerie; Göttgens Berthold
Gata2, Fli1, and Scl form a recursively wired gene-regulatory circuit during early hematopoietic development.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(45):17692-7.
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2007: Scott Linda M; Beer Philip A; Bench Anthony J; Erber Wendy N; Green Anthony R
Prevalance of JAK2 V617F and exon 12 mutations in polycythaemia vera.
British journal of haematology 2007;139(3):511-2.
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2007: Ogilvy S; Ferreira R; Piltz S G; Bowen J M; Göttgens B; Green A R
The SCL +40 enhancer targets the midbrain together with primitive and definitive hematopoiesis and is regulated by SCL and GATA proteins.
Molecular and cellular biology 2007;27(20):7206-19.
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2007: McMullin Mary F; Reilly John T; Campbell Peter; Bareford David; Green Anthony R; Harrison Claire N; Conneally Eibhlin; Ryan Kate;
Amendment to the guideline for diagnosis and investigation of polycythaemia/erythrocytosis.
British journal of haematology 2007;138(6):821-2.
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2007: Bradley Cara K; Takano Elena A; Göthert Joachim R; Göttgens Berthold; Green Anthony R; Begley C Glenn; van Eekelen J Anke M
Temporal regulation of Cre-recombinase activity in Scl-positive neurons of the central nervous system.
Genesis (New York, N.Y. : 2000) 2007;45(3):145-51.
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2007: Patterson Lucy J; Gering Martin; Eckfeldt Craig E; Green Anthony R; Verfaillie Catherine M; Ekker Stephen C; Patient Roger
The transcription factors Scl and Lmo2 act together during development of the hemangioblast in zebrafish.
Blood 2007;109(6):2389-98.
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2007: Chan Wan Y I; Follows George A; Lacaud Georges; Pimanda John E; Landry Josette-Renee; Kinston Sarah; Knezevic Kathy; Piltz Sandie; Donaldson Ian J; Gambardella Laure; Sablitzky Fred; Green Anthony R; Kouskoff Valerie; Göttgens Berthold
The paralogous hematopoietic regulators Lyl1 and Scl are coregulated by Ets and GATA factors, but Lyl1 cannot rescue the early Scl-/- phenotype.
Blood 2007;109(5):1908-16.
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2007: Naderi A; Teschendorff A E; Barbosa-Morais N L; Pinder S E; Green A R; Powe D G; Robertson J F R; Aparicio S; Ellis I O; Brenton J D; Caldas C
A gene-expression signature to predict survival in breast cancer across independent data sets.
Oncogene 2007;26(10):1507-16.
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2007: Scott Linda M; Tong Wei; Levine Ross L; Scott Mike A; Beer Philip A; Stratton Michael R; Futreal P Andrew; Erber Wendy N; McMullin Mary Frances; Harrison Claire N; Warren Alan J; Gilliland D Gary; Lodish Harvey F; Green Anthony R
JAK2 exon 12 mutations in polycythemia vera and idiopathic erythrocytosis.
The New England journal of medicine 2007;356(5):459-68.
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2007: Pimanda John E; Donaldson Ian J; de Bruijn Marella F T R; Kinston Sarah; Knezevic Kathy; Huckle Liz; Piltz Sandie; Landry Josette-Renée; Green Anthony R; Tannahill David; Göttgens Berthold
The SCL transcriptional network and BMP signaling pathway interact to regulate RUNX1 activity.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(3):840-5.
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2007: Zhao Rui; Oxley David; Smith Trevor S; Follows George A; Green Anthony R; Alexander Denis R
DNA damage-induced Bcl-xL deamidation is mediated by NHE-1 antiport regulated intracellular pH.
PLoS biology 2007;5(1):e1.
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2007: Follows George A; Janes Mary E; Vallier Ludovic; Green Anthony R; Gottgens Berthold
Real-time PCR mapping of DNaseI-hypersensitive sites using a novel ligation-mediated amplification technique.
Nucleic acids research 2007;35(8):e56.
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2006: Campbell Peter J; Green Anthony R
The myeloproliferative disorders.
The New England journal of medicine 2006;355(23):2452-66.
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2006: Campbell Peter J; Baxter E Joanna; Beer Philip A; Scott Linda M; Bench Anthony J; Huntly Brian J P; Erber Wendy N; Kusec Rajko; Larsen Thomas Stauffer; Giraudier Stéphane; Le Bousse-Kerdilès Marie-Caroline; Griesshammer Martin; Reilly John T; Cheung Betty Y; Harrison Claire N; Green Anthony R
Mutation of JAK2 in the myeloproliferative disorders: timing, clonality studies, cytogenetic associations, and role in leukemic transformation.
Blood 2006;108(10):3548-55.
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2006: Follows George A; Dhami Pawan; Göttgens Berthold; Bruce Alexander W; Campbell Peter J; Dillon Shane C; Smith Aileen M; Koch Christoph; Donaldson Ian J; Scott Mike A; Dunham Ian; Janes Mary E; Vetrie David; Green Anthony R
Identifying gene regulatory elements by genomic microarray mapping of DNaseI hypersensitive sites.
Genome research 2006;16(10):1310-9.
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2006: Scott Linda M; Scott Mike A; Campbell Peter J; Green Anthony R
Progenitors homozygous for the V617F mutation occur in most patients with polycythemia vera, but not essential thrombocythemia.
Blood 2006;108(7):2435-7.
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2006: Vassiliou George S; Campbell Peter J; Li Juan; Roberts Ian; Swanton Soheila; Huntly Brian J P; Fourouclas Nasios; Baxter E Joanna; Munro Laura R; Culligan Dominic A; Scott Linda M; Green Anthony R
An acquired translocation in JAK2 Val617Phe-negative essential thrombocythemia associated with autosomal spread of X-inactivation.
Haematologica 2006;91(8):1100-4.
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2006: Fourouclas Nasios; Campbell Peter J; Bench Anthony J; Swanton Soheila; Baxter E Joanna; Huntly Brian Jp; Green Anthony R
Size matters: the prognostic implications of large and small deletions of the derivative 9 chromosome in chronic myeloid leukemia.
Haematologica 2006;91(7):952-5.
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2006: Pimanda John E; Chan W Y Iris; Donaldson Ian J; Bowen Mark; Green Anthony R; Göttgens Berthold
Endoglin expression in the endothelium is regulated by Fli-1, Erg, and Elf-1 acting on the promoter and a -8-kb enhancer.
Blood 2006;107(12):4737-45.
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2006: Pimanda John E; Silberstein Lev; Dominici Massimo; Dekel Benjamin; Bowen Mark; Oldham Scott; Kallianpur Asha; Brandt Stephen J; Tannahill David; Göttgens Berthold; Green Anthony R
Transcriptional link between blood and bone: the stem cell leukemia gene and its +19 stem cell enhancer are active in bone cells.
Molecular and cellular biology 2006;26(7):2615-25.
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2006: Percy Melanie J; Jones Frank G C; Green Anthony R; Reilly John T; McMullin Mary Frances
The incidence of the JAK2 V617F mutation in patients with idiopathic erythrocytosis.
Haematologica 2006;91(3):413-4.
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2006: Campbell Peter J; Griesshammer Martin; Döhner Konstanze; Döhner Hartmut; Kusec Rajko; Hasselbalch Hans C; Larsen Thomas Stauffer; Pallisgaard Niels; Giraudier Stéphane; Le Bousse-Kerdilès Marie-Caroline; Desterke Christophe; Guerton Bernadette; Dupriez Brigitte; Bordessoule Dominique; Fenaux Pierre; Kiladjian Jean-Jacques; Viallard Jean-François; Brière Jean; Harrison Claire N; Green Anthony R; Reilly John T
V617F mutation in JAK2 is associated with poorer survival in idiopathic myelofibrosis.
Blood 2006;107(5):2098-100.
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2006: Campbell Peter J; Scott Linda M; Baxter E Joanna; Bench Anthony J; Green Anthony R; Erber Wendy N
Methods for the detection of the JAK2 V617F mutation in human myeloproliferative disorders.
Methods in molecular medicine 2006;125():253-64.
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2005: Campbell Peter J; Scott Linda M; Buck Georgina; Wheatley Keith; East Clare L; Marsden Joanne T; Duffy Audrey; Boyd Elaine M; Bench Anthony J; Scott Mike A; Vassiliou George S; Milligan Donald W; Smith Steve R; Erber Wendy N; Bareford David; Wilkins Bridget S; Reilly John T; Harrison Claire N; Green Anthony R;
Definition of subtypes of essential thrombocythaemia and relation to polycythaemia vera based on JAK2 V617F mutation status: a prospective study.
Lancet 2005;366(9501):1945-53.
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2005: Scott Linda M; Campbell Peter J; Baxter E Joanna; Todd Tony; Stephens Philip; Edkins Sarah; Wooster Richard; Stratton Michael R; Futreal P Andrew; Green Anthony R
The V617F JAK2 mutation is uncommon in cancers and in myeloid malignancies other than the classic myeloproliferative disorders.
Blood 2005;106(8):2920-1.
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2005: Li Juan; Bench Anthony J; Piltz Sandie; Vassiliou George; Baxter E Joanna; Ferguson-Smith Anne C; Green Anthony R
L3mbtl, the mouse orthologue of the imprinted L3MBTL, displays a complex pattern of alternative splicing and escapes genomic imprinting.
Genomics 2005;86(4):489-94.
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2005: Silberstein Lev; Sánchez María-José; Socolovsky Merav; Liu Ying; Hoffman Gary; Kinston Sarah; Piltz Sandie; Bowen Mark; Gambardella Laure; Green Anthony R; Göttgens Berthold
Transgenic analysis of the stem cell leukemia +19 stem cell enhancer in adult and embryonic hematopoietic and endothelial cells.
Stem cells (Dayton, Ohio) 2005;23(9):1378-88.
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2005: Bloor Adrian J C; Kotsopoulou Ekaterina; Hayward Penny; Champion Brian R; Green Anthony R
RFP represses transcriptional activation by bHLH transcription factors.
Oncogene 2005;24(45):6729-36.
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2005: Landry Josette-Renée; Kinston Sarah; Knezevic Kathy; Donaldson Ian J; Green Anthony R; Göttgens Berthold
Fli1, Elf1, and Ets1 regulate the proximal promoter of the LMO2 gene in endothelial cells.
Blood 2005;106(8):2680-7.
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2005: McMullin Mary F; Bareford D; Campbell P; Green A R; Harrison Claire; Hunt Beverley; Oscier D; Polkey M I; Reilly J T; Rosenthal E; Ryan Kate; Pearson T C; Wilkins Bridget;
Guidelines for the diagnosis, investigation and management of polycythaemia/erythrocytosis.
British journal of haematology 2005;130(2):174-95.
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2005: Harrison Claire N; Campbell Peter J; Buck Georgina; Wheatley Keith; East Clare L; Bareford David; Wilkins Bridget S; van der Walt Jon D; Reilly John T; Grigg Andrew P; Revell Paul; Woodcock Barrie E; Green Anthony R;
Hydroxyurea compared with anagrelide in high-risk essential thrombocythemia.
The New England journal of medicine 2005;353(1):33-45.
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2005: Delabesse E; Ogilvy S; Chapman M A; Piltz S G; Gottgens B; Green A R
Transcriptional regulation of the SCL locus: identification of an enhancer that targets the primitive erythroid lineage in vivo.
Molecular and cellular biology 2005;25(12):5215-25.
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2005: Göthert Joachim R; Gustin Sonja E; Hall Mark A; Green Anthony R; Göttgens Berthold; Izon David J; Begley C Glenn
In vivo fate-tracing studies using the Scl stem cell enhancer: embryonic hematopoietic stem cells significantly contribute to adult hematopoiesis.
Blood 2005;105(7):2724-32.
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2005: Baxter E Joanna; Scott Linda M; Campbell Peter J; East Clare; Fourouclas Nasios; Swanton Soheila; Vassiliou George S; Bench Anthony J; Boyd Elaine M; Curtin Natasha; Scott Mike A; Erber Wendy N; Green Anthony R;
Acquired mutation of the tyrosine kinase JAK2 in human myeloproliferative disorders.
Lancet 2005;365(9464):1054-61.
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2005: Donaldson Ian J; Chapman Michael; Kinston Sarah; Landry Josette Renée; Knezevic Kathy; Piltz Sandie; Buckley Noel; Green Anthony R; Göttgens Berthold
Genome-wide identification of cis-regulatory sequences controlling blood and endothelial development.
Human molecular genetics 2005;14(5):595-601.
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2004: Bench Anthony J; Li Juan; Huntly Brian J P; Delabesse Eric; Fourouclas Nasios; Hunt Adrienne R; Deloukas Panos; Green Anthony R
Characterization of the imprinted polycomb gene L3MBTL, a candidate 20q tumour suppressor gene, in patients with myeloid malignancies.
British journal of haematology 2004;127(5):509-18.
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2004: Göthert Joachim R; Gustin Sonja E; van Eekelen J Anke M; Schmidt Uli; Hall Mark A; Jane Stephen M; Green Anthony R; Göttgens Berthold; Izon David J; Begley C Glenn
Genetically tagging endothelial cells in vivo: bone marrow-derived cells do not contribute to tumor endothelium.
Blood 2004;104(6):1769-77.
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2004: Kluin-Nelemans Hanneke C; Buck Georgina; le Cessie Saskia; Richards Sue; Beverloo H Berna; Falkenburg J H Frederik; Littlewood Tim; Muus Petra; Bareford David; van der Lelie Hans; Green Anthony R; Roozendaal Klaas J; Milne Alison E; Chapman Claire S; Shepherd Patricia;
Randomized comparison of low-dose versus high-dose interferon-alfa in chronic myeloid leukemia: prospective collaboration of 3 joint trials by the MRC and HOVON groups.
Blood 2004;103(12):4408-15.
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2004: Li Juan; Bench Anthony J; Vassiliou George S; Fourouclas Nasios; Ferguson-Smith Anne C; Green Anthony R
Imprinting of the human L3MBTL gene, a polycomb family member located in a region of chromosome 20 deleted in human myeloid malignancies.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(19):7341-6.
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2004: Göttgens Berthold; Broccardo Cyril; Sanchez Maria-Jose; Deveaux Sophie; Murphy George; Göthert Joachim R; Kotsopoulou Ekaterini; Kinston Sarah; Delaney Liz; Piltz Sandie; Barton Linda M; Knezevic Kathy; Erber Wendy N; Begley C Glenn; Frampton Jonathan; Green Anthony R
The scl +18/19 stem cell enhancer is not required for hematopoiesis: identification of a 5' bifunctional hematopoietic-endothelial enhancer bound by Fli-1 and Elf-1.
Molecular and cellular biology 2004;24(5):1870-83.
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2004: Chapman Michael A; Donaldson Ian J; Gilbert James; Grafham Darren; Rogers Jane; Green Anthony R; Göttgens Berthold
Analysis of multiple genomic sequence alignments: a web resource, online tools, and lessons learned from analysis of mammalian SCL loci.
Genome research 2004;14(2):313-8.
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2004: Green Anthony R; Vassiliou George S; Curtin Natasha; Campbell Peter J
Management of the myeloproliferative disorders : distinguishing data from dogma.
The hematology journal : the official journal of the European Haematology Association / EHA 2004;5 Suppl 3():S126-32.
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2003: Reid Alistair G; Swanton Soheila; Grace Colin; Campbell Lynda J; Green Anthony R; Nacheva Ellie P;
Double Philadelphia masquerading as chromosome 20q deletion--a new recurrent abnormality in chronic myeloid leukaemia blast crisis.
British journal of haematology 2003;123(3):442-8.
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2003: Murphy George J; Göttgens Berthold; Vegiopoulos Alexandros; Sanchez Maria-José; Leavitt Andrew D; Watson Stephen P; Green Anthony R; Frampton Jon
Manipulation of mouse hematopoietic progenitors by specific retroviral infection.
The Journal of biological chemistry 2003;278(44):43556-63.
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2003: Huntly Brian J P; Guilhot Francois; Reid Alistair G; Vassiliou George; Hennig Evelin; Franke Christina; Byrne Jennie; Brizard Andre; Niederwieser Dietger; Freeman-Edward Julie; Cuthbert Gavin; Bown Nick; Clark Richard E; Nacheva Elizabeth P; Green Anthony R; Deininger Michael W N
Imatinib improves but may not fully reverse the poor prognosis of patients with CML with derivative chromosome 9 deletions.
Blood 2003;102(6):2205-12.
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2003: Gribble Susan M; Reid Alistair G; Roberts Ian; Grace Colin; Green Anthony R; Nacheva Elizabeth P
Genomic imbalances in CML blast crisis: 8q24.12-q24.13 segment identified as a common region of over-representation.
Genes, chromosomes & cancer 2003;37(4):346-58.
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2003: Huntly Brian J P; Bench Anthony; Green Anthony R
Double jeopardy from a single translocation: deletions of the derivative chromosome 9 in chronic myeloid leukemia.
Blood 2003;102(4):1160-8.
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2003: Gribble S M; Reid A G; Bench A J; Huntly B J P; Grace C; Green A R; Nacheva E P
Molecular cytogenetics of polycythaemia vera: lack of occult rearrangements detectable by 20q LSP screening, CGH, and M-FISH.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2003;17(7):1419-21.
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2003: Reid Alistair G; Huntly Brian J P; Grace Colin; Green Anthony R; Nacheva Elisabeth P
Survival implications of molecular heterogeneity in variant Philadelphia-positive chronic myeloid leukaemia.
British journal of haematology 2003;121(3):419-27.
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2003: Chapman Michael A; Charchar Fadi J; Kinston Sarah; Bird Christine P; Grafham Darren; Rogers Jane; Grützner Frank; Graves Jennifer A Marshall; Green Anthony R; Göttgens Berthold
Comparative and functional analyses of LYL1 loci establish marsupial sequences as a model for phylogenetic footprinting.
Genomics 2003;81(3):249-59.
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2003: Delabesse Eric; Li Juan; Schnittger Susanne; Hiddemann Wolfgang; Green Anthony R
Absence of SCL mutations in myeloid malignancies.
British journal of haematology 2003;120(3):482-3.
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2002: Chen Chang-Zheng; Li Min; de Graaf David; Monti Stefano; Göttgens Berthold; Sanchez Maria-Jose; Lander Eric S; Golub Todd R; Green Anthony R; Lodish Harvey F
Identification of endoglin as a functional marker that defines long-term repopulating hematopoietic stem cells.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(24):15468-73.
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2002: Göttgens Berthold; Nastos Aristotelis; Kinston Sarah; Piltz Sandie; Delabesse Eric C M; Stanley Maureen; Sanchez Maria-Jose; Ciau-Uitz Aldo; Patient Roger; Green Anthony R
Establishing the transcriptional programme for blood: the SCL stem cell enhancer is regulated by a multiprotein complex containing Ets and GATA factors.
The EMBO journal 2002;21(12):3039-50.
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2002: Huntly Brian J P; Bench Anthony J; Delabesse Eric; Reid Alistair G; Li Juan; Scott Mike A; Campbell Lynda; Byrne Jennie; Pinto Eleanor; Brizard Andre; Niedermeiser Deitger; Nacheva Elizabeth P; Guilhot Francois; Deininger Michael; Green Anthony R
Derivative chromosome 9 deletions in chronic myeloid leukemia: poor prognosis is not associated with loss of ABL-BCR expression, elevated BCR-ABL levels, or karyotypic instability.
Blood 2002;99(12):4547-53.
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2002: Sinclair Angus M; Bench Anthony J; Bloor Adrian J C; Li Juan; Göttgens Berthold; Stanley Maureen L; Miller Jane; Piltz Sandie; Hunter Susie; Nacheva Elisabeth P; Sanchez María-José; Green Anthony R
Rescue of the lethal scl(-/-) phenotype by the human SCL locus.
Blood 2002;99(11):3931-8.
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2002: Göttgens Berthold; Barton Linda M; Chapman Michael A; Sinclair Angus M; Knudsen Bjarne; Grafham Darren; Gilbert James G R; Rogers Jane; Bentley David R; Green Anthony R
Transcriptional regulation of the stem cell leukemia gene (SCL)--comparative analysis of five vertebrate SCL loci.
Genome research 2002;12(5):749-59.
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2002: Bloor Adrian J C; Sánchez María-José; Green Anthony R; Göttgens Berthold
The role of the stem cell leukemia (SCL) gene in hematopoietic and endothelial lineage specification.
Journal of hematotherapy & stem cell research 2002;11(2):195-206.
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2002: Reid Alistair G; Huntly Brian J P; Hennig Eveline; Niederwieser Dietger; Campbell Lynda J; Bown Nick; Telford Nick; Walker Helen; Grace Colin D; Deininger Michael W; Green Anthony R; Nacheva Elisabeth P
Deletions of the derivative chromosome 9 do not account for the poor prognosis associated with Philadelphia-positive acute lymphoblastic leukemia.
Blood 2002;99(6):2274-5.
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2001: Li J; Bench A J; Huntly B J; Green A R
Mutation and methylation analysis of the transforming growth factor beta receptor II gene in polycythaemia vera.
British journal of haematology 2001;115(4):872-80.
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2001: Sánchez M J; Bockamp E O; Miller J; Gambardella L; Green A R
Selective rescue of early haematopoietic progenitors in Scl(-/-) mice by expressing Scl under the control of a stem cell enhancer.
Development (Cambridge, England) 2001;128(23):4815-27.
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2001: Bench A J; Cross N C; Huntly B J; Nacheva E P; Green A R
Myeloproliferative disorders.
Best practice & research. Clinical haematology 2001;14(3):531-51.
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2001: Huntly B J; Reid A G; Bench A J; Campbell L J; Telford N; Shepherd P; Szer J; Prince H M; Turner P; Grace C; Nacheva E P; Green A R
Deletions of the derivative chromosome 9 occur at the time of the Philadelphia translocation and provide a powerful and independent prognostic indicator in chronic myeloid leukemia.
Blood 2001;98(6):1732-8.
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2001: Barton L M; Gottgens B; Gering M; Gilbert J G; Grafham D; Rogers J; Bentley D; Patient R; Green A R
Regulation of the stem cell leukemia (SCL) gene: a tale of two fishes.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(12):6747-52.
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2001: Reid A; Gribble S M; Huntly B J; Andrews K M; Campbell L; Grace C D; Wood M E; Green A R; Nacheva E P
Variant Philadelphia translocations in chronic myeloid leukaemia can mimic typical blast crisis chromosome abnormalities or classic t(9;22): a report of two cases.
British journal of haematology 2001;113(2):439-42.
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2001: Reid A; Gribble S M; Andrews K M; Green A R; Nacheva E P
Chromosome band specific FISH probes allow improved detection of terminal translocations in leukaemic metaphases.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2001;15(5):860-1.
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2001: Göttgens B; Gilbert J G; Barton L M; Grafham D; Rogers J; Bentley D R; Green A R
Long-range comparison of human and mouse SCL loci: localized regions of sensitivity to restriction endonucleases correspond precisely with peaks of conserved noncoding sequences.
Genome research 2001;11(1):87-97.
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2000: Bench A J; Nacheva E P; Hood T L; Holden J L; French L; Swanton S; Champion K M; Li J; Whittaker P; Stavrides G; Hunt A R; Huntly B J; Campbell L J; Bentley D R; Deloukas P; Green A R
Chromosome 20 deletions in myeloid malignancies: reduction of the common deleted region, generation of a PAC/BAC contig and identification of candidate genes. UK Cancer Cytogenetics Group (UKCCG).
Oncogene 2000;19(34):3902-13.
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2000: Green A R
Haemangioblast origin of chronic myeloid leukaemia?
Lancet 2000;355(9216):1659-60.
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2000: Gribble S M; Roberts I; Grace C; Andrews K M; Green A R; Nacheva E P
Cytogenetics of the chronic myeloid leukemia-derived cell line K562: karyotype clarification by multicolor fluorescence in situ hybridization, comparative genomic hybridization, and locus-specific fluorescence in situ hybridization.
Cancer genetics and cytogenetics 2000;118(1):1-8.
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2000: Göttgens B; Barton L M; Gilbert J G; Bench A J; Sanchez M J; Bahn S; Mistry S; Grafham D; McMurray A; Vaudin M; Amaya E; Bentley D R; Green A R; Sinclair A M
Analysis of vertebrate SCL loci identifies conserved enhancers.
Nature biotechnology 2000;18(2):181-6.
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2000: Sinclair P B; Nacheva E P; Leversha M; Telford N; Chang J; Reid A; Bench A; Champion K; Huntly B; Green A R
Large deletions at the t(9;22) breakpoint are common and may identify a poor-prognosis subgroup of patients with chronic myeloid leukemia.
Blood 2000;95(3):738-43.
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1999: Göttgens B; Barton L M; Grafham D; Vaudin M; Green A R
Tdr2, a new zebrafish transposon of the Tc1 family.
Gene 1999;239(2):373-9.
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1999: Barton L M; Göttgens B; Green A R
The stem cell leukaemia (SCL) gene: a critical regulator of haemopoietic and vascular development.
The international journal of biochemistry & cell biology 1999;31(10):1193-207.
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1999: Sánchez M; Göttgens B; Sinclair A M; Stanley M; Begley C G; Hunter S; Green A R
An SCL 3' enhancer targets developing endothelium together with embryonic and adult haematopoietic progenitors.
Development (Cambridge, England) 1999;126(17):3891-904.
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1999: Green A R
The pathogenesis and management of essential thrombocythaemia.
Haematologica 1999;84 Suppl EHA-4():36-9.
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1999: Fordham J L; Göttgens B; McLaughlin F; Green A R
Chromatin structure and transcriptional regulation of the stem cell leukaemia (SCL) gene in mast cells.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1999;13(5):750-9.
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1999: Gribble S M; Sinclair P B; Grace C; Green A R; Nacheva E P
Comparative analysis of G-banding, chromosome painting, locus-specific fluorescence in situ hybridization, and comparative genomic hybridization in chronic myeloid leukemia blast crisis.
Cancer genetics and cytogenetics 1999;111(1):7-17.
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1999: Sinclair A M; Göttgens B; Barton L M; Stanley M L; Pardanaud L; Klaine M; Gering M; Bahn S; Sanchez M; Bench A J; Fordham J L; Bockamp E; Green A R
Distinct 5' SCL enhancers direct transcription to developing brain, spinal cord, and endothelium: neural expression is mediated by GATA factor binding sites.
Developmental biology 1999;209(1):128-42.
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1998: Bench A J; Nacheva E P; Champion K M; Green A R
Molecular genetics and cytogenetics of myeloproliferative disorders.
Baillière's clinical haematology 1998;11(4):819-48.
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1998: Bockamp E O; Fordham J L; Göttgens B; Murrell A M; Sanchez M J; Green A R
Transcriptional regulation of the stem cell leukemia gene by PU.1 and Elf-1.
The Journal of biological chemistry 1998;273(44):29032-42.
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1998: Gering M; Rodaway A R; Göttgens B; Patient R K; Green A R
The SCL gene specifies haemangioblast development from early mesoderm.
The EMBO journal 1998;17(14):4029-45.
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1998: Bench A J; Aldred M A; Humphray S J; Champion K M; Gilbert J G; Asimakopoulos F A; Deloukas P; Gwilliam R; Bentley D R; Green A R
A detailed physical and transcriptional map of the region of chromosome 20 that is deleted in myeloproliferative disorders and refinement of the common deleted region.
Genomics 1998;49(3):351-62.
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1998: Göttgens B; Gilbert J G; Barton L M; Aparicio S; Hawker K; Mistry S; Vaudin M; King A; Bentley D; Elgar G; Green A R
The pufferfish SLP-1 gene, a new member of the SCL/TAL-1 family of transcription factors.
Genomics 1998;48(1):52-62.
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1998: Nacheva E P; Grace C D; Bittner M; Ledbetter D H; Jenkins R B; Green A R
Comparative genomic hybridization: a comparison with molecular and cytogenetic analysis.
Cancer genetics and cytogenetics 1998;100(2):93-105.
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1997: Hinshelwood S; Bench A J; Green A R
Pathogenesis of polycythaemia vera.
Blood reviews 1997;11(4):224-32.
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1997: Göttgens B; McLaughlin F; Bockamp E O; Fordham J L; Begley C G; Kosmopoulos K; Elefanty A G; Green A R
Transcription of the SCL gene in erythroid and CD34 positive primitive myeloid cells is controlled by a complex network of lineage-restricted chromatin-dependent and chromatin-independent regulatory elements.
Oncogene 1997;15(20):2419-28.
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1997: Sinclair P B; Green A R; Grace C; Nacheva E P
Improved sensitivity of BCR-ABL detection: a triple-probe three-color fluorescence in situ hybridization system.
Blood 1997;90(4):1395-402.
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1997: Champion K M; Gilbert J G; Asimakopoulos F A; Hinshelwood S; Green A R
Clonal haemopoiesis in normal elderly women: implications for the myeloproliferative disorders and myelodysplastic syndromes.
British journal of haematology 1997;97(4):920-6.
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1997: Asimakopoulos F A; Hinshelwood S; Gilbert J G; Delibrias C C; Göttgens B; Fearon D T; Green A R
The gene encoding hematopoietic cell phosphatase (SHP-1) is structurally and transcriptionally intact in polycythemia vera.
Oncogene 1997;14(10):1215-22.
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1997: Bockamp E O; McLaughlin F; Göttgens B; Murrell A M; Elefanty A G; Green A R
Distinct mechanisms direct SCL/tal-1 expression in erythroid cells and CD34 positive primitive myeloid cells.
The Journal of biological chemistry 1997;272(13):8781-90.
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1996: Asimakopoulos F A; Green A R
Deletions of chromosome 20q and the pathogenesis of myeloproliferative disorders.
British journal of haematology 1996;95(2):219-26.
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1996: Asimakopoulos F A; Gilbert J G; Aldred M A; Pearson T C; Green A R
Interstitial deletion constitutes the major mechanism for loss of heterozygosity on chromosome 20q in polycythemia vera.
Blood 1996;88(7):2690-8.
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1996: Green A R
Pathogenesis of polycythaemia vera.
Lancet 1996;347(9005):844-5.
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1996: Asimakopoulos F A; Holloway T L; Nacheva E P; Scott M A; Fenaux P; Green A R
Detection of chromosome 20q deletions in bone marrow metaphases but not peripheral blood granulocytes in patients with myeloproliferative disorders or myelodysplastic syndromes.
Blood 1996;87(4):1561-70.
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1996: Asimakopoulos F A; White N J; Nacheva E P; Green A R
The human CD40 gene lies within chromosome 20q deletions associated with myeloid malignancies.
British journal of haematology 1996;92(1):127-30.
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1995: Bockamp E O; McLaughlin F; Murrell A M; Göttgens B; Robb L; Begley C G; Green A R
Lineage-restricted regulation of the murine SCL/TAL-1 promoter.
Blood 1995;86(4):1502-14.
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1995: Nacheva E; Grace C; Holloway T L; Green A R
Comparative genomic hybridization in acute myeloid leukemia. A comparison with G-banding and chromosome painting.
Cancer genetics and cytogenetics 1995;82(1):9-16.
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1995: Murrell A M; Bockamp E O; Göttgens B; Chan Y S; Cross M A; Heyworth C M; Green A R
Discordant regulation of SCL/TAL-1 mRNA and protein during erythroid differentiation.
Oncogene 1995;11(1):131-9.
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1995: Nacheva E; Holloway T; Carter N; Grace C; White N; Green A R
Characterization of 20q deletions in patients with myeloproliferative disorders or myelodysplastic syndromes.
Cancer genetics and cytogenetics 1995;80(2):87-94.
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1995: Göttgens B; Green A R
Retinoic acid and the differentiation of lymphohaemopoietic stem cells.
BioEssays : news and reviews in molecular, cellular and developmental biology 1995;17(3):187-9.
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1995: Murrell A M; Green A R
Regulation of lineage restricted haemopoietic transcription factors in cell hybrids.
Oncogene 1995;10(4):631-9.
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1994: Asimakopoulos F A; White N J; Nacheva E; Green A R
Molecular analysis of chromosome 20q deletions associated with myeloproliferative disorders and myelodysplastic syndromes.
Blood 1994;84(9):3086-94.
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1994: Cross M A; Heyworth C M; Murrell A M; Bockamp E O; Dexter T M; Green A R
Expression of lineage restricted transcription factors precedes lineage specific differentiation in a multipotent haemopoietic progenitor cell line.
Oncogene 1994;9(10):3013-6.
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1994: Mahendra P; Ager S; Bedlow A J; Bloxham D M; Green A R; Marcus R E
Two unusual neurological presentations of granulocytic sarcoma in Philadelphia positive chronic myeloid leukaemia.
Leukemia & lymphoma 1994;15(3-4):351-5.
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1994: Bockamp E O; McLaughlin F; Murrell A; Green A R
Transcription factors and the regulation of haemopoiesis: lessons from GATA and SCL proteins.
BioEssays : news and reviews in molecular, cellular and developmental biology 1994;16(7):481-8.
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1994: Tanigawa T; Robb L; Green A R; Begley C G
Constitutive expression of the putative transcription factor SCL associated with proviral insertion in the myeloid leukemic cell line WEHI-3BD-.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1994;5(6):557-61.
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1994: Nacheva E; Holloway T; Brown K; Bloxham D; Green A R
Philadelphia-negative chronic myeloid leukaemia: detection by FISH of BCR-ABL fusion gene localized either to chromosome 9 or chromosome 22.
British journal of haematology 1994;87(2):409-12.
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1994: White N J; Nacheva E; Asimakopoulos F A; Bloxham D; Paul B; Green A R
Deletion of chromosome 20q in myelodysplasia can occur in a multipotent precursor of both myeloid cells and B cells.
Blood 1994;83(10):2809-16.
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1994: Williamson D; Beresford C H; Langdown J V; Anderson C C; Green A R
Polycythaemia associated with homozygosity for the abnormal haemoglobin Sherwood Forest (beta 104 (G6)Arg-->Thr).
British journal of haematology 1994;86(4):890-2.
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1994: Elwood N J; Green A R; Melder A; Begley C G; Nicola N
The SCL protein displays cell-specific heterogeneity in size.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1994;8(1):106-14.
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1994: Begley C G; Robb L; Rockman S; Visvader J; Bockamp E O; Chan Y S; Green A R
Structure of the gene encoding the murine SCL protein.
Gene 1994;138(1-2):93-9.
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1993: Richards E M; Bloxham D M; Nacheva E; Marcus R E; Green A R
BCR rearrangement in apparent essential thrombocythaemia.
British journal of haematology 1993;85(3):625-6.
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1993: Green A R
Chromosomal deletions in haematological malignancies.
Lancet 1993;341(8860):1567-8.
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1993: Green A R; Rockman S; DeLuca E; Begley C G
Induced myeloid differentiation of K562 cells with downregulation of erythroid and megakaryocytic transcription factors: a novel experimental model for hemopoietic lineage restriction.
Experimental hematology 1993;21(4):525-31.
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1992: Green A R; Begley C G
SCL and related hemopoietic helix-loop-helix transcription factors.
International journal of cell cloning 1992;10(5):269-76.
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1992: Green A R
Transcription factors, translocations and haematological malignancies.
Blood reviews 1992;6(2):118-24.
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1992: Begley C G; Lipkowitz S; Göbel V; Mahon K A; Bertness V; Green A R; Gough N M; Kirsch I R
Molecular characterization of NSCL, a gene encoding a helix-loop-helix protein expressed in the developing nervous system.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(1):38-42.
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1991: Green A R; DeLuca E; Begley C G
Antisense SCL suppresses self-renewal and enhances spontaneous erythroid differentiation of the human leukaemic cell line K562.
The EMBO journal 1991;10(13):4153-8.
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1991: Green A R; Salvaris E; Begley C G
Erythroid expression of the 'helix-loop-helix' gene, SCL.
Oncogene 1991;6(3):475-9.
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1991: Begley C G; Visvader J; Green A R; Aplan P D; Metcalf D; Kirsch I R; Gough N M
Molecular cloning and chromosomal localization of the murine homolog of the human helix-loop-helix gene SCL.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(3):869-73.
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