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Hitoshi Arita
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50
Hanasaki, Kohji
12
Ishizaki, J
10
Higashino, K
8
Ono, Takashi
8
Yokota, Yasunori
6
Saiga, Akihiko
6
Nakano, K
5
Ikeda, Minoru
5
Ishimoto, Yoshikazu
4
Morioka, Yasuhide
4
Fujii, N
3
Ohtani, Mitsuaki
2
Suzuki, N
2
Yamada, Katsutoshi
2
Notoya, Mitsuru
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All Publications
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2005: Saiga Akihiko; Uozumi Naonori; Ono Takashi; Seno Kaoru; Ishimoto Yoshikazu; Arita Hitoshi; Shimizu Takao; Hanasaki Kohji
Group X secretory phospholipase A2 can induce arachidonic acid release and eicosanoid production without activation of cytosolic phospholipase A2 alpha.
Prostaglandins & other lipid mediators 2005;75(1-4):79-89.
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2003: Hanasaki Kohji; Arita Hitoshi
Biological functions of group X secretory PLA2.
Advances in experimental medicine and biology 2003;525():93-6.
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2002: Silliman Christopher C; Moore Ernest E; Zallen Garret; Gonzalez Ricardo; Johnson Jeffrey L; Elzi David J; Meng Xianzhong; Hanasaki Kohji; Ishizaki Jun; Arita Hitoshi; Ao Lihua; England Kelly M; Banerjee Anirban
Presence of the M-type sPLA(2) receptor on neutrophils and its role in elastase release and adhesion.
American journal of physiology. Cell physiology 2002;283(4):C1102-13.
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2002: Hanasaki Kohji; Arita Hitoshi
Phospholipase A2 receptor: a regulator of biological functions of secretory phospholipase A2.
Prostaglandins & other lipid mediators 2002;68-69():71-82.
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2002: Hanasaki Kohji; Yamada Katsutoshi; Yamamoto Shigenori; Ishimoto Yoshikazu; Saiga Akihiko; Ono Takashi; Ikeda Minoru; Notoya Mitsuru; Kamitani Shigeki; Arita Hitoshi
Potent modification of low density lipoprotein by group X secretory phospholipase A2 is linked to macrophage foam cell formation.
The Journal of biological chemistry 2002;277(32):29116-24.
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2002: Higashino Ki Ken-ichi; Yokota Yasunori; Ono Takashi; Kamitani Shigeki; Arita Hitoshi; Hanasaki Kohji
Identification of a soluble form phospholipase A2 receptor as a circulating endogenous inhibitor for secretory phospholipase A2.
The Journal of biological chemistry 2002;277(16):13583-8.
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2001: Yokota Y; Notoya M; Higashino K; Ishimoto Y; Nakano K; Arita H; Hanasaki K
Clearance of group X secretory phospholipase A(2) via mouse phospholipase A(2) receptor.
FEBS letters 2001;509(2):250-4.
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2001: Saiga A; Morioka Y; Ono T; Nakano K; Ishimoto Y; Arita H; Hanasaki K
Group X secretory phospholipase A(2) induces potent productions of various lipid mediators in mouse peritoneal macrophages.
Biochimica et biophysica acta 2001;1530(1):67-76.
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2000: Morioka Y; Ikeda M; Saiga A; Fujii N; Ishimoto Y; Arita H; Hanasaki K
Potential role of group X secretory phospholipase A(2) in cyclooxygenase-2-dependent PGE(2) formation during colon tumorigenesis.
FEBS letters 2000;487(2):262-6.
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2000: Morioka Y; Saiga A; Yokota Y; Suzuki N; Ikeda M; Ono T; Nakano K; Fujii N; Ishizaki J; Arita H; Hanasaki K
Mouse group X secretory phospholipase A2 induces a potent release of arachidonic acid from spleen cells and acts as a ligand for the phospholipase A2 receptor.
Archives of biochemistry and biophysics 2000;381(1):31-42.
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2000: Yokota Y; Higashino K; Nakano K; Arita H; Hanasaki K
Identification of group X secretory phospholipase A(2) as a natural ligand for mouse phospholipase A(2) receptor.
FEBS letters 2000;478(1-2):187-91.
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2000: Yokota Y; Ikeda M; Higashino K; Nakano K; Fujii N; Arita H; Hanasaki K
Enhanced tissue expression and elevated circulating level of phospholipase A(2) receptor during murine endotoxic shock.
Archives of biochemistry and biophysics 2000;379(1):7-17.
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1999: Hanasaki K; Arita H
Biological and pathological functions of phospholipase A(2) receptor.
Archives of biochemistry and biophysics 1999;372(2):215-23.
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1999: Hanasaki K; Ono T; Saiga A; Morioka Y; Ikeda M; Kawamoto K; Higashino K; Nakano K; Yamada K; Ishizaki J; Arita H
Purified group X secretory phospholipase A(2) induced prominent release of arachidonic acid from human myeloid leukemia cells.
The Journal of biological chemistry 1999;274(48):34203-11.
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1999: Murakami M; Kambe T; Shimbara S; Higashino K; Hanasaki K; Arita H; Horiguchi M; Arita M; Arai H; Inoue K; Kudo I
Different functional aspects of the group II subfamily (Types IIA and V) and type X secretory phospholipase A(2)s in regulating arachidonic acid release and prostaglandin generation. Implications of cyclooxygenase-2 induction and phospholipid scramblase-mediated cellular membrane perturbation.
The Journal of biological chemistry 1999;274(44):31435-44.
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1999: Ishizaki J; Suzuki N; Higashino K; Yokota Y; Ono T; Kawamoto K; Fujii N; Arita H; Hanasaki K
Cloning and characterization of novel mouse and human secretory phospholipase A(2)s.
The Journal of biological chemistry 1999;274(35):24973-9.
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1999: Arita H
[Structure and function of phospholipase A2 receptor]
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 1999;44(8 Suppl):1025-31.
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1999: Yokota Y; Hanasaki K; Ono T; Nakazato H; Kobayashi T; Arita H
Suppression of murine endotoxic shock by sPLA2 inhibitor, indoxam, through group IIA sPLA2-independent mechanisms.
Biochimica et biophysica acta 1999;1438(2):213-22.
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1997: Hanasaki K; Yokota Y; Ishizaki J; Itoh T; Arita H
Resistance to endotoxic shock in phospholipase A2 receptor-deficient mice.
The Journal of biological chemistry 1997;272(52):32792-7.
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1995: Fujita H; Kawamoto K; Hanasaki K; Arita H
Glycosylation-dependent binding of pancreatic type I phospholipase A2 to its specific receptor.
Biochemical and biophysical research communications 1995;209(1):293-9.
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1995: Nakano T; Higashino K; Kikuchi N; Kishino J; Nomura K; Fujita H; Ohara O; Arita H
Vascular smooth muscle cell-derived, Gla-containing growth-potentiating factor for Ca(2+)-mobilizing growth factors.
The Journal of biological chemistry 1995;270(11):5702-5.
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1995: Kishino J; Kawamoto K; Ishizaki J; Verheij H M; Ohara O; Arita H
Pancreatic-type phospholipase A2 activates prostaglandin E2 production in rat mesangial cells by receptor binding reaction.
Journal of biochemistry 1995;117(2):420-4.
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1995: Ishizaki J; Higashino K; Ohara O; Arita H
Structural characterization of pancreatic group I phospholipase A2 receptor.
Advances in prostaglandin, thromboxane, and leukotriene research 1995;23():85-7.
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1995: Ohara O; Ishizaki J; Arita H
Structure and function of phospholipase A2 receptor.
Progress in lipid research 1995;34(2):117-38.
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1994: Higashino K; Ishizaki J; Kishino J; Ohara O; Arita H
Structural comparison of phospholipase-A2-binding regions in phospholipase-A2 receptors from various mammals.
European journal of biochemistry / FEBS 1994;225(1):375-82.
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1994: Tohkin M; Kakudo S; Kasai H; Arita H
Comparative study of inhibitory effects by murine interferon gamma and a new bisphosphonate (alendronate) in hypercalcemic, nude mice bearing human tumor (LJC-1-JCK).
Cancer immunology, immunotherapy : CII 1994;39(3):155-60.
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1994: Kishino J; Ohara O; Nomura K; Kramer R M; Arita H
Pancreatic-type phospholipase A2 induces group II phospholipase A2 expression and prostaglandin biosynthesis in rat mesangial cells.
The Journal of biological chemistry 1994;269(7):5092-8.
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1994: Ishizaki J; Hanasaki K; Higashino K; Kishino J; Kikuchi N; Ohara O; Arita H
Molecular cloning of pancreatic group I phospholipase A2 receptor.
The Journal of biological chemistry 1994;269(8):5897-904.
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1994: Nakano T; Fujita H; Kikuchi N; Arita H
Plasmin converts pro-form of group I phospholipase A2 into receptor binding, active forms.
Biochemical and biophysical research communications 1994;198(1):10-5.
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1993: Tanaka K; Arita H; Inoue K
[Phospholipase A2 inhibitors]
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 1993;38(11):1987-99.
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1993: Ishizaki J; Kishino J; Teraoka H; Ohara O; Arita H
Receptor-binding capability of pancreatic phospholipase A2 is separable from its enzymatic activity.
FEBS letters 1993;324(3):349-52.
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1993: Arita H; Hanasaki K
Physiological aspects of a high affinity binding site for pancreatic-type phospholipase A2.
Journal of lipid mediators 1993;6(1-3):217-22.
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1993: Tohkin M; Kishino J; Ishizaki J; Arita H
Pancreatic-type phospholipase A2 stimulates prostaglandin synthesis in mouse osteoblastic cells (MC3T3-E1) via a specific binding site.
The Journal of biological chemistry 1993;268(4):2865-71.
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1992: Nakajima M; Hanasaki K; Ueda M; Arita H
Effect of pancreatic type phospholipase A2 on isolated porcine cerebral arteries via its specific binding sites.
FEBS letters 1992;309(3):261-4.
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1992: Hanasaki K; Arita H
Purification and characterization of a high-affinity binding protein for pancreatic-type phospholipase A2.
Biochimica et biophysica acta 1992;1127(3):233-41.
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1992: Kishino J; Tohkin M; Arita H
Proliferative effect of phospholipase A2 in rat chondrocyte via its specific binding sites.
Biochemical and biophysical research communications 1992;186(2):1025-31.
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1992: Nomura K; Teraoka H; Arita H; Ohara O
Disorganization of microfilaments is accompanied by downregulation of alpha-smooth muscle actin isoform mRNA level in cultured vascular smooth muscle cells.
Journal of biochemistry 1992;112(1):102-6.
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1992: Kanemasa T; Arimura A; Kishino J; Ohtani M; Arita H
Contraction of guinea pig lung parenchyma by pancreatic type phospholipase A2 via its specific binding site.
FEBS letters 1992;303(2-3):217-20.
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1992: Ohara O; Arita H
[Molecular aspects of mammalian phospholipases A2 from the standpoint of arachidonic acid release]
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 1992;37(6):898-905.
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1992: Kanemasa T; Hanasaki K; Arita H
Migration of vascular smooth muscle cells by phospholipase A2 via specific binding sites.
Biochimica et biophysica acta 1992;1125(2):210-4.
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1992: Hanasaki K; Arita H
Characterization of a high affinity binding site for pancreatic-type phospholipase A2 in the rat. Its cellular and tissue distribution.
The Journal of biological chemistry 1992;267(9):6414-20.
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1991: Arita H; Hanasaki K; Nakano T; Oka S; Teraoka H; Matsumoto K
Novel proliferative effect of phospholipase A2 in Swiss 3T3 cells via specific binding site.
The Journal of biological chemistry 1991;266(29):19139-41.
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1991: Kakushi H; Shike T; Hayasaki Y; Arita H; Uchida K
[Effect of (+)-S-145 calcium salt dihydrate, an orally active antagonist of the thromboxane A2/prostaglandin endoperoxide receptor, on platelet aggregation]
Nippon yakurigaku zasshi. Folia pharmacologica Japonica 1991;98(2):113-20.
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1991: Kishino J; Hanasaki K; Nagasaki T; Arita H
Kinetic studies on stereospecific recognition by the thromboxane A2/prostaglandin H2 receptor of the antagonist, S-145.
British journal of pharmacology 1991;103(4):1883-8.
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1991: Oka S; Arita H
Inflammatory factors stimulate expression of group II phospholipase A2 in rat cultured astrocytes. Two distinct pathways of the gene expression.
The Journal of biological chemistry 1991;266(15):9956-60.
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1991: Kurihara H; Nakano T; Takasu N; Arita H
Intracellular localization of group II phospholipase A2 in rat vascular smooth muscle cells and its possible relationship to eicosanoid formation.
Biochimica et biophysica acta 1991;1082(3):285-92.
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1991: Kishino J; Hanasaki K; Kato T; Arita H
Synergistic effect of thromboxane A2 and N-formylmethionylleucylphenylalanine on platelet-activating factor synthesis in human polymorphonuclear neutrophils.
Biochimica et biophysica acta 1991;1092(2):169-74.
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1991: Kishino J; Hanasaki K; Kato T; Arita H
Endothelin-induced intracellular Ca2+ mobilization through its specific receptors in murine peritoneal macrophages.
FEBS letters 1991;280(1):103-6.
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1991: Arita H
[Phospholipid metabolism in vascular endothelial cells]
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 1991;36(3):216-21.
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1991: Hanasaki K; Kishi M; Arita H
Phorbol ester-induced expression of the common, low-affinity binding site for primary prostanoids in vascular smooth muscle cells.
Advances in prostaglandin, thromboxane, and leukotriene research 1991;21A():363-6.
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1991: Arita H; Nakano T; Ohara O; Teraoka H
Activation of group II phospholipase A2 gene via two distinct mechanisms in rat vascular smooth muscle cells.
Advances in prostaglandin, thromboxane, and leukotriene research 1991;21A():277-80.
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1990: Ohara O; Ishizaki J; Nakano T; Arita H; Teraoka H
A simple and sensitive method for determining transcription initiation site: identification of two transcription initiation sites in rat group II phospholipase A2 gene.
Nucleic acids research 1990;18(23):6997-7002.
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1990: Hanasaki K; Nakano T; Arita H
Receptor-mediated mitogenic effect of thromboxane A2 in vascular smooth muscle cells.
Biochemical pharmacology 1990;40(11):2535-42.
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1990: Nakano T; Arita H
Enhanced expression of group II phospholipase A2 gene in the tissues of endotoxin shock rats and its suppression by glucocorticoid.
FEBS letters 1990;273(1-2):23-6.
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1990: Nakano T; Ohara O; Teraoka H; Arita H
Glucocorticoids suppress group II phospholipase A2 production by blocking mRNA synthesis and post-transcriptional expression.
The Journal of biological chemistry 1990;265(21):12745-8.
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1990: Hanasaki K; Kishi M; Arita H
Phorbol ester-induced expression of the common, low-affinity binding site for primary prostanoids in vascular smooth muscle cells.
The Journal of biological chemistry 1990;265(9):4871-5.
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1990: Nakano T; Ohara O; Teraoka H; Arita H
Group II phospholipase A2 mRNA synthesis is stimulated by two distinct mechanisms in rat vascular smooth muscle cells.
FEBS letters 1990;261(1):171-4.
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1990: Watanabe S; Umeda M; Nomura T; Kobayashi T; Nakano T; Arita H; Utsumi H; Sasaki M S; Inoue K
Mitogenic response of near-diploid mouse cell line m5S/1M induced by epidermal growth factor.
Journal of cellular physiology 1990;142(1):99-107.
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1990: Kamata S; Haga N; Tsuri T; Uchida K; Kakushi H; Arita H; Hanasaki K
Synthesis of thromboxane receptor antagonists with bicyclo[3.1.0]hexane ring systems.
Journal of medicinal chemistry 1990;33(1):229-39.
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1989: Nakano T; Matsumoto S; Hanasaki K; Arita H
Platelet activation by tetraprenol via stimulation of phospholipase A2 action.
Journal of biochemistry 1989;106(5):887-93.
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1989: Nakano T; Hanasaki K; Arita H
Role of protein kinase C in U46619-induced platelet shape change, aggregation and secretion.
Thrombosis research 1989;56(2):299-306.
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1989: Hanasaki K; Arita H
A common binding site for primary prostanoids in vascular smooth muscles: a definitive discrimination of the binding for thromboxane A2/prostaglandin H2 receptor agonist from its antagonist.
Biochimica et biophysica acta 1989;1013(1):28-35.
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1989: Hanasaki K; Nakano K; Kasai H; Arita H
Biochemical characterization and comparison of rat thromboxane A2/prostaglandin H2 receptors in platelets and cultured aortic smooth muscle cells.
Biochemical pharmacology 1989;38(18):2967-76.
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1989: Hanasaki K; Nagasaki T; Arita H
Characterization of platelet thromboxane A2/prostaglandin H2 receptor by a novel thromboxane receptor antagonist, [3H]S-145.
Biochemical pharmacology 1989;38(12):2007-17.
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1989: Nakano T; Hanasaki K; Arita H
Possible involvement of cytoskeleton in collagen-stimulated activation of phospholipases in human platelets.
The Journal of biological chemistry 1989;264(10):5400-6.
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1989: Arita H; Nakano T; Hanasaki K
Thromboxane A2: its generation and role in platelet activation.
Progress in lipid research 1989;28(4):273-301.
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1989: Narisada M; Ohtani M; Watanabe F; Uchida K; Arita H; Doteuchi M; Ueda M; Hanasaki K; Kakushi H; Otani K
Synthesis and in vitro effects on platelets and vascular smooth muscle of S-145, a novel thromboxane receptor antagonist.
Advances in prostaglandin, thromboxane, and leukotriene research 1989;19():659-62.
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1988: Hanasaki K; Arita H
Characterization of thromboxane A2/prostaglandin H2 (TXA2/PGH2) receptors of rat platelets and their interaction with TXA2/PGH2 receptor antagonists.
Biochemical pharmacology 1988;37(20):3923-9.
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1988: Narisada M; Ohtani M; Watanabe F; Uchida K; Arita H; Doteuchi M; Hanasaki K; Kakushi H; Otani K; Hara S
Synthesis and in vitro activity of various derivatives of a novel thromboxane receptor antagonist, (+/-)-(5Z)-7-[3-endo-[(phenylsulfonyl)amino]bicyclo[2.2.1] hept-2-exo-yl]heptenoic acid.
Journal of medicinal chemistry 1988;31(9):1847-54.
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1988: Nakano T; Hanasaki K; Matsumoto S; Arita H
Retinol induces platelet aggregation via activation of phospholipase A2.
Biochemical and biophysical research communications 1988;154(3):1075-80.
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1988: Nakano T; Hanasaki K; Arita H
Different effects of two thromboxane A2/prostaglandin H2 receptor ligands, U46619 and S-145, on rabbit platelets.
FEBS letters 1988;234(2):309-12.
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1988: Hanasaki K; Arita H
Characterization of a new compound, S-145, as a specific TXA2 receptor antagonist in platelets.
Thrombosis research 1988;50(3):365-76.
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1988: Hanasaki K; Nakano K; Kasai H; Kurihara H; Arita H
Identification of thromboxane A2 receptor in cultured vascular endothelial cells of rat aorta.
Biochemical and biophysical research communications 1988;151(3):1352-7.
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1988: Hanasaki K; Nakano K; Kasai H; Arita H; Ohtani K; Doteuchi M
Specific receptors for thromboxane A2 in cultured vascular smooth muscle cells of rat aorta.
Biochemical and biophysical research communications 1988;150(3):1170-5.
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1987: Nakano T; Hanasaki K; Arita H
Involvement of the Na+/H+ antiporter in activation of rat platelets by collagen.
Journal of biochemistry 1987;102(4):677-80.
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1987: Nakano T; Terawaki A; Arita H
Influence of beta-lactam antibiotics on platelets. II. In vitro effects of some beta-lactam antibiotics on the biochemical responses of rat platelets.
Journal of pharmacobio-dynamics 1987;10(8):408-20.
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1987: Hanasaki K; Nakano T; Arita H
Biphasic action of phospholipase A in collagen-stimulated rat platelets.
Journal of biochemistry 1987;102(1):5-8.
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1987: Nakano T; Terawaki A; Arita H
Signal transduction in collagen-stimulated rat platelets is composed of three stages.
Journal of biochemistry 1987;101(5):1169-80.
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