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Kosuke Aritake

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Hematopoietic System

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Kohji Yamamoto; Kosuke Aritake; Akifumi Higashiura; Mamoru Suzuki; Nobuko Uodome; Yoshihiro Urade; Atsushi Nakagawa
Crystal structure of a Bombyx mori sigma-class glutathione transferase exhibiting prostaglandin E synthase activity.
Takahisa Murata; Takayuki Nakagawa; Masataka Nakamura; Shuh Narumiya; Kosuke Aritake; Hiroyuki Hirai; Masatoshi Hori; Toshihiko Maruyama; Yoshiki Tsubosaka; Yoshihiro Urade; Hiroshi Ozaki
Anti-inflammatory role of PGD2 in acute lung inflammation and therapeutic application of its signal enhancement.
Pascal Philibert; Charles Sultan; Yoshihiro Urade; Kosuke Aritake; Anu Bashamboo; Brigitte Boizet-Bonhoure; Juliane Leger; Françoise Paris; Francis Poulat
Unilateral cryptorchidism in mice mutant for Ptgds.

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2013: Kohji Yamamoto; Kosuke Aritake; Akifumi Higashiura; Mamoru Suzuki; Nobuko Uodome; Yoshihiro Urade; Atsushi Nakagawa
Crystal structure of a Bombyx mori sigma-class glutathione transferase exhibiting prostaglandin E synthase activity.
Biochimica et biophysica acta 2013;1830(6):3711-8.
2013: Takahisa Murata; Takayuki Nakagawa; Masataka Nakamura; Shuh Narumiya; Kosuke Aritake; Hiroyuki Hirai; Masatoshi Hori; Toshihiko Maruyama; Yoshiki Tsubosaka; Yoshihiro Urade; Hiroshi Ozaki
Anti-inflammatory role of PGD2 in acute lung inflammation and therapeutic application of its signal enhancement.
Proceedings of the National Academy of Sciences of the United States of America 2013;110(13):5205-10.
2013: Pascal Philibert; Charles Sultan; Yoshihiro Urade; Kosuke Aritake; Anu Bashamboo; Brigitte Boizet-Bonhoure; Juliane Leger; Françoise Paris; Francis Poulat
Unilateral cryptorchidism in mice mutant for Ptgds.
Human mutation 2013;34(2):278-82.
2012: Kentaro Kaneko; Michael Lazarus; Chihiro Miyamoto; Nanae Nagata; Shuh Narumiya; Yo Oishi; Yoshihiro Urade; Shuzhang Yang; Masaaki Yoshikawa; Kosuke Aritake; Tomoyuki Furuyashiki; Kousaku Ohinata
Orally administered rubiscolin-6, a δ opioid peptide derived from Rubisco, stimulates food intake via leptomeningeal lipocallin-type prostaglandin D synthase in mice.
Molecular nutrition & food research 2012;56(8):1315-23.
2012: Yuji Kado; Hiroyoshi Matsumura; Yousuke Okano; Nobuo Okazaki; Nobuko Uodome; Yoshihiro Urade; Kosuke Aritake; Tsuyoshi Inoue
Human hematopoietic prostaglandin D synthase inhibitor complex structures.
Journal of biochemistry 2012;151(4):447-55.
2012: Tsuyoshi Tajima; Yoshihiro Urade; Kosuke Aritake; Toshiyuki Matsuoka; Masaki Michishita; Takahisa Murata; Shuh Narumiya; Hiroshi Ozaki; Masatoshi Hori
EP2 and EP4 receptors on muscularis resident macrophages mediate LPS-induced intestinal dysmotility via iNOS upregulation through cAMP/ERK signals.
American journal of physiology. Gastrointestinal and liver physiology 2012;302(5):G524-34.
2012: Mika Masaki; Yukihiro Shoyama; Hiroyuki Tanaka; Kosuke Aritake; Zhi-Li Huang; Yoshihiro Urade
Crocin promotes non-rapid eye movement sleep in mice.
Molecular nutrition & food research 2012;56(2):304-8.
2011: Takahisa Murata; Takayuki Nakagawa; Yoshihiro Urade; Kosuke Aritake; Masatoshi Hori; Shinya Kamauchi; Shigeko Matsumoto; Eiichi Momotani; Hiroshi Ozaki
Prostagladin D2 is a mast cell-derived antiangiogenic factor in lung carcinoma.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(49):19802-7.
2011: Brigitte Moniot; Serge Nef; Francis Poulat; Yoshihiro Urade; Kosuke Aritake; Faustine Declosmenil; Naomi Eguchi; Andalib Farhat; Brigitte Boizet-Bonhoure
Hematopoietic prostaglandin D synthase (H-Pgds) is expressed in the early embryonic gonad and participates to the initial nuclear translocation of the SOX9 protein.
Developmental dynamics : an official publication of the American Association of Anatomists 2011;240(10):2335-43.
2011: Yoshihiro Yamamoto; Hiroo Yokozeki; Yoshihiro Urade; Kosuke Aritake; Hiroyuki Hirai; Kinya Nagata; Masataka Nakamura; Shuh Narumiya; Shinobu Otani; Takahiro Satoh
Dual functions of prostaglandin D2 in murine contact hypersensitivity via DP and CRTH2.
The American journal of pathology 2011;179(1):302-14.
2011: Etsushi Kuroda; Ken J Ishii; Satoshi Uematsu; Keiichi Ohata; Cevayir Coban; Shizuo Akira; Kosuke Aritake; Yoshihiro Urade; Yasuo Morimoto
Silica crystals and aluminum salts regulate the production of prostaglandin in macrophages via NALP3 inflammasome-independent mechanisms.
Immunity 2011;34(4):514-26.
2011: Mitsunari Ogasawara; Akira Hirose; Masafumi Ono; Kosuke Aritake; Yasuko Nozaki; Masaya Takahashi; Nobuto Okamoto; Shuji Sakamoto; Shinji Iwasaki; Taketoshi Asanuma; Taketoshi Taniguchi; Yoshihiro Urade; Saburo Onishi; Toshiji Saibara; Jude A Oben
A novel and comprehensive mouse model of human non-alcoholic steatohepatitis with the full range of dysmetabolic and histological abnormalities induced by gold thioglucose and a high-fat diet.
Liver international : official journal of the International Association for the Study of the Liver 2011;31(4):542-51.
2011: Ryota Hokari; Chie Kurihara; Nanae Nagata; Kosuke Aritake; Yoshikiyo Okada; Chikako Watanabe; Shunsuke Komoto; Mitsuyasu Nakamura; Atsushi Kawaguchi; Shigeaki Nagao; Yoshihiro Urade; Soichiro Miura
Increased expression of lipocalin-type-prostaglandin D synthase in ulcerative colitis and exacerbating role in murine colitis.
American journal of physiology. Gastrointestinal and liver physiology 2011;300(3):G401-8.
2011: Hiroaki Tanaka; Toshiharu Tsurumura; Kosuke Aritake; Naoki Furubayashi; Sachiko Takahashi; Mari Yamanaka; Erika Hirota; Satoshi Sano; Masaru Sato; Tomoyuki Kobayashi; Tetsuo Tanaka; Koji Inaka; Yoshihiro Urade
Improvement in the quality of hematopoietic prostaglandin D synthase crystals in a microgravity environment.
Journal of synchrotron radiation 2011;18(1):88-91.
2010: Kosuke Aritake; Chang-Sung Koh; Atsushi Inoue; Fumie Yabuuchi; Kunihiko Kitagaki; Yukihiro Ikoma; Shigehiro Hayashi
Effects of human recombinant-interferon β in experimental autoimmune encephalomyelitis in guinea pigs.
Pharmaceutical biology 2010;48(11):1273-9.
2010: Sachiko Takahashi; Toshiharu Tsurumura; Kosuke Aritake; Naoki Furubayashi; Masaru Sato; Mari Yamanaka; Erika Hirota; Satoshi Sano; Tomoyuki Kobayashi; Tetsuo Tanaka; Koji Inaka; Hiroaki Tanaka; Yoshihiro Urade
High-quality crystals of human haematopoietic prostaglandin D synthase with novel inhibitors.
Acta crystallographica. Section F, Structural biology and crystallization communications 2010;66(Pt 7):846-50.
2010: Ko Fujimori; Toshiyuki Ueno; Nanae Nagata; Kaori Kashiwagi; Kosuke Aritake; Fumio Amano; Yoshihiro Urade
Suppression of adipocyte differentiation by aldo-keto reductase 1B3 acting as prostaglandin F2alpha synthase.
The Journal of biological chemistry 2010;285(12):8880-6.
2010: Yasushi Fujitani; Kosuke Aritake; Yoshihide Kanaoka; Tsuyoshi Goto; Nobuyuki Takahashi; Ko Fujimori; Teruo Kawada
Pronounced adipogenesis and increased insulin sensitivity caused by overproduction of prostaglandin D2 in vivo.
The FEBS journal 2010;277(6):1410-9.
2010: Chieko Shimura; Takahiro Satoh; Ken Igawa; Kosuke Aritake; Yoshihiro Urade; Masataka Nakamura; Hiroo Yokozeki
Dendritic cells express hematopoietic prostaglandin D synthase and function as a source of prostaglandin D2 in the skin.
The American journal of pathology 2010;176(1):227-37.
2009: Takashi Kumasaka; Kosuke Aritake; Hideo Ago; Daisuke Irikura; Toshiharu Tsurumura; Masaki Yamamoto; Masashi Miyano; Yoshihiro Urade; Osamu Hayaishi
Structural basis of the catalytic mechanism operating in open-closed conformers of lipocalin type prostaglandin D synthase.
The Journal of biological chemistry 2009;284(33):22344-52.
2009: Brigitte Moniot; Faustine Declosmenil; Francisco Barrionuevo; Gerd Scherer; Kosuke Aritake; Safia Malki; Laetitia Marzi; Anne Cohen-Solal; Ina Georg; Jürgen Klattig; Christoph Englert; Yuna Kim; Blanche Capel; Naomi Eguchi; Yoshihiro Urade; Brigitte Boizet-Bonhoure; Francis Poulat
The PGD2 pathway, independently of FGF9, amplifies SOX9 activity in Sertoli cells during male sexual differentiation.
Development (Cambridge, England) 2009;136(11):1813-21.
2009: Ikuko Mohri; Kosuke Aritake; Hidetoshi Taniguchi; Yo Sato; Shinya Kamauchi; Nanae Nagata; Toshihiko Maruyama; Masako Taniike; Yoshihiro Urade
Inhibition of prostaglandin D synthase suppresses muscular necrosis.
The American journal of pathology 2009;174(5):1735-44.
2009: Daisuke Irikura; Kosuke Aritake; Nanae Nagata; Toshihiko Maruyama; Shigeru Shimamoto; Yoshihiro Urade
Biochemical, functional, and pharmacological characterization of AT-56, an orally active and selective inhibitor of lipocalin-type prostaglandin D synthase.
The Journal of biological chemistry 2009;284(12):7623-30.
2008: Ko Fujimori; Kosuke Aritake; Yoshihiro Urade
Enhancement of prostaglandin D(2) production through cyclooxygenase-2 and lipocalin-type prostaglandin D synthase by upstream stimulatory factor 1 in human brain-derived TE671 cells under serum starvation.
Gene 2008;426(1-2):72-80.
2008: Tsuyoshi Tajima; Takahisa Murata; Kosuke Aritake; Yoshihiro Urade; Hiroyuki Hirai; Masataka Nakamura; Hiroshi Ozaki; Masatoshi Hori
Lipopolysaccharide induces macrophage migration via prostaglandin D(2) and prostaglandin E(2).
The Journal of pharmacology and experimental therapeutics 2008;326(2):493-501.
2007: Shigeru Shimamoto; Takuya Yoshida; Takashi Inui; Keigo Gohda; Yuji Kobayashi; Ko Fujimori; Toshiharu Tsurumura; Kosuke Aritake; Yoshihiro Urade; Tadayasu Ohkubo
NMR solution structure of lipocalin-type prostaglandin D synthase: evidence for partial overlapping of catalytic pocket and retinoic acid-binding pocket within the central cavity.
The Journal of biological chemistry 2007;282(43):31373-9.
2007: Ko Fujimori; Kosuke Aritake; Yoshihiro Urade
A novel pathway to enhance adipocyte differentiation of 3T3-L1 cells by up-regulation of lipocalin-type prostaglandin D synthase mediated by liver X receptor-activated sterol regulatory element-binding protein-1c.
The Journal of biological chemistry 2007;282(25):18458-66.
2007: Hidetoshi Taniguchi; Ikuko Mohri; Hitomi Okabe-Arahori; Kosuke Aritake; Kazuko Wada; Takahisa Kanekiyo; Shuh Narumiya; Masahiro Nakayama; Keiichi Ozono; Yoshihiro Urade; Masako Taniike
Prostaglandin D2 protects neonatal mouse brain from hypoxic ischemic injury.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2007;27(16):4303-12.
2007: Takahisa Kanekiyo; Tadato Ban; Kosuke Aritake; Zhi-Li Huang; Wei-Min Qu; Issay Okazaki; Ikuko Mohri; Shigeo Murayama; Keiichi Ozono; Masako Taniike; Yuji Goto; Yoshihiro Urade
Lipocalin-type prostaglandin D synthase/beta-trace is a major amyloid beta-chaperone in human cerebrospinal fluid.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(15):6412-7.
2007: Jae Man Park; Yoshihide Kanaoka; Naomi Eguchi; Kosuke Aritake; Sava Grujic; Alicia M Materi; Virgilio S Buslon; Brigette L Tippin; Alan M Kwong; Eduardo Salido; Samuel W French; Yoshihiro Urade; Henry J Lin
Hematopoietic prostaglandin D synthase suppresses intestinal adenomas in ApcMin/+ mice.
Cancer research 2007;67(3):881-9.
2007: Daisuke Irikura; Takashi Inui; Carsten T Beuckmann; Kosuke Aritake; Gerhard Schreiber; Masashi Miyano; Tsuyoshi Inoue; Yoshihiro Urade
Characterization of a major secretory protein in the cane toad (Bufo marinus) choroid plexus as an amphibian lipocalin-type prostaglandin D synthase.
Journal of biochemistry 2007;141(2):173-80.
2006: Wei-Min Qu; Zhi-Li Huang; Xin-Hong Xu; Kosuke Aritake; Naomi Eguchi; Fumio Nambu; Shuh Narumiya; Yoshihiro Urade; Osamu Hayaishi
Lipocalin-type prostaglandin D synthase produces prostaglandin D2 involved in regulation of physiological sleep.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(47):17949-54.
2006: Takahiro Satoh; Rie Moroi; Kosuke Aritake; Yoshihiro Urade; Yasumasa Kanai; Koji Sumi; Hiroo Yokozeki; Hiroyuki Hirai; Kinya Nagata; Toshifumi Hara; Masanori Utsuyama; Katsuiku Hirokawa; Kazuo Sugamura; Kiyoshi Nishioka; Masataka Nakamura
Prostaglandin D2 plays an essential role in chronic allergic inflammation of the skin via CRTH2 receptor.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(4):2621-9.
2006: Yuichi Mazaki; Shigeru Hashimoto; Tohru Tsujimura; Masaki Morishige; Ari Hashimoto; Kosuke Aritake; Atsuko Yamada; Jin-Min Nam; Hiroshi Kiyonari; Kazuki Nakao; Hisataka Sabe
Neutrophil direction sensing and superoxide production linked by the GTPase-activating protein GIT2.
Nature immunology 2006;7(7):724-31.
2006: Ko Fujimori; Takashi Inui; Nobuko Uodome; Keiichi Kadoyama; Kosuke Aritake; Yoshihiro Urade
Zebrafish and chicken lipocalin-type prostaglandin D synthase homologues: Conservation of mammalian gene structure and binding ability for lipophilic molecules, and difference in expression profile and enzyme activity.
Gene 2006;375():14-25.
2006: Kosuke Aritake; Yuji Kado; Tsuyoshi Inoue; Masashi Miyano; Yoshihiro Urade
Structural and functional characterization of HQL-79, an orally selective inhibitor of human hematopoietic prostaglandin D synthase.
The Journal of biological chemistry 2006;281(22):15277-86.
2006: Ikuko Mohri; Masako Taniike; Issei Okazaki; Kuriko Kagitani-Shimono; Kosuke Aritake; Takahisa Kanekiyo; Takashi Yagi; Shoichi Takikita; Hyung-Suk Kim; Yoshihiro Urade; Kinuko Suzuki
Lipocalin-type prostaglandin D synthase is up-regulated in oligodendrocytes in lysosomal storage diseases and binds gangliosides.
Journal of neurochemistry 2006;97(3):641-51.
2006: Ikuko Mohri; Masako Taniike; Hidetoshi Taniguchi; Takahisa Kanekiyo; Kosuke Aritake; Takashi Inui; Noriko Fukumoto; Naomi Eguchi; Atsuko Kushi; Hitoshi Sasai; Yoshihide Kanaoka; Keiichi Ozono; Shuh Narumiya; Kinuko Suzuki; Yoshihiro Urade
Prostaglandin D2-mediated microglia/astrocyte interaction enhances astrogliosis and demyelination in twitcher.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2006;26(16):4383-93.
2004: Tsuyoshi Inoue; Yousuke Okano; Yuji Kado; Kosuke Aritake; Daisuke Irikura; Nobuko Uodome; Nobuo Okazaki; Shigehiro Kinugasa; Hideyuki Shishitani; Hiroyoshi Matsumura; Yasushi Kai; Yoshihiro Urade
First determination of the inhibitor complex structure of human hematopoietic prostaglandin D synthase.
Journal of biochemistry 2004;135(3):279-83.
2004: Yoshihiro Urade; Naomi Eguchi; Kosuke Aritake; Osamu Hayaishi
[Functional analyses of lipocalin-type and hematopoietic prostaglandin D synthases].
Nihon yakurigaku zasshi. Folia pharmacologica Japonica 2004;123(1):5-13.
2002: Yasushi Fujitani; Yoshihide Kanaoka; Kosuke Aritake; Nobuko Uodome; Kazue Okazaki-Hatake; Yoshihiro Urade
Pronounced eosinophilic lung inflammation and Th2 cytokine release in human lipocalin-type prostaglandin D synthase transgenic mice.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(1):443-9.