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Andy Greenfield

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Laura L Yates; Debora Bogani; Lauren Chessum; Caroline J Formstone; Andy Greenfield; Lee Hazelwood; Helen Hilton; Jennifer N Murdoch; Lee A Niswander; Anju Paudyal; M Rosario Romero; Jeremy Sanderson; Carsten Schnatwinkel; Jonathan Wilde; Charlotte H Dean
Scribble is required for normal epithelial cell-cell contacts and lumen morphogenesis in the mammalian lung.
Nick Warr; Sara Wells; Debora Bogani; Rachel Brixey; Gwenn-Aël Carre; Melissa Childers; Ivan del Barco Barrantes; Jessica Vitos Faleato; Angel R Nebreda; Madeleine Pope; Cheryl L Scudamore; Pam Siggers; Marianna Tedesco; Paul A Trainor; Andy Greenfield
Gadd45γ and Map3k4 interactions regulate mouse testis determination via p38 MAPK-mediated control of Sry expression.
Helen B Pearson; Pedro A Perez-Mancera; Andrew Ryan; Ronald Simon; Pierre Tennstedt; David A Tuveson; Debora Bogani; Lukas E Dow; Imogen Elsum; Andy Greenfield; Patrick O Humbert
SCRIB expression is deregulated in human prostate cancer, and its deficiency in mice promotes prostate neoplasia.

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All Publications

2013: Laura L Yates; Debora Bogani; Lauren Chessum; Caroline J Formstone; Andy Greenfield; Lee Hazelwood; Helen Hilton; Jennifer N Murdoch; Lee A Niswander; Anju Paudyal; M Rosario Romero; Jeremy Sanderson; Carsten Schnatwinkel; Jonathan Wilde; Charlotte H Dean
Scribble is required for normal epithelial cell-cell contacts and lumen morphogenesis in the mammalian lung.
Developmental biology 2013;373(2):267-80.
2012: Nick Warr; Sara Wells; Debora Bogani; Rachel Brixey; Gwenn-Aël Carre; Melissa Childers; Ivan del Barco Barrantes; Jessica Vitos Faleato; Angel R Nebreda; Madeleine Pope; Cheryl L Scudamore; Pam Siggers; Marianna Tedesco; Paul A Trainor; Andy Greenfield
Gadd45γ and Map3k4 interactions regulate mouse testis determination via p38 MAPK-mediated control of Sry expression.
Developmental cell 2012;23(5):1020-31.
2011: Helen B Pearson; Pedro A Perez-Mancera; Andrew Ryan; Ronald Simon; Pierre Tennstedt; David A Tuveson; Debora Bogani; Lukas E Dow; Imogen Elsum; Andy Greenfield; Patrick O Humbert
SCRIB expression is deregulated in human prostate cancer, and its deficiency in mice promotes prostate neoplasia.
The Journal of clinical investigation 2011;121(11):4257-67.
2011: Sarah Field; Kerry-Lyn Riley; Daniel T Grimes; Helen Hilton; Michelle Simon; Nicola Powles-Glover; Pam Siggers; Debora Bogani; Andy Greenfield; Dominic P Norris
Pkd1l1 establishes left-right asymmetry and physically interacts with Pkd2.
Development (Cambridge, England) 2011;138(6):1131-42.
2011: Nick Warr; Debora Bogani; Pam Siggers; Rachel Brixey; Hilda Tateossian; Asha Dopplapudi; Sara Wells; Michael Cheeseman; Ying Xia; Harry Ostrer; Andy Greenfield
Minor abnormalities of testis development in mice lacking the gene encoding the MAPK signalling component, MAP3K1.
PloS one 2011;6(5):e19572.
2009: Debora Bogani; Pam Siggers; Rachel Brixey; Nick Warr; Sarah Beddow; Jessica Edwards; Debbie Williams; Dagmar Wilhelm; Peter Koopman; Richard A Flavell; Hongbo Chi; Harry Ostrer; Sara Wells; Michael Cheeseman; Andy Greenfield
Loss of mitogen-activated protein kinase kinase kinase 4 (MAP3K4) reveals a requirement for MAPK signalling in mouse sex determination.
PLoS biology 2009;7(9):e1000196.
2009: Victoria L Patterson; Christine Damrau; Anju Paudyal; Benjamin Reeve; Daniel T Grimes; Michelle E Stewart; Debbie J Williams; Pam Siggers; Andy Greenfield; Jennifer N Murdoch
Mouse hitchhiker mutants have spina bifida, dorso-ventral patterning defects and polydactyly: identification of Tulp3 as a novel negative regulator of the Sonic hedgehog pathway.
Human molecular genetics 2009;18(10):1719-39.
2009: Laura M Pastorelli; Sara Wells; Martin Fray; Adrian Smith; Tertius A Hough; Brian D Harfe; Michael McManus; Lee Smith; Adrian S Woolf; Michael Cheeseman; Andy Greenfield
Genetic analyses reveal a requirement for Dicer1 in the mouse urogenital tract.
Mammalian genome : official journal of the International Mammalian Genome Society 2009;20(3):140-51.
2009: Nick Warr; Pam Siggers; Debora Bogani; Rachel Brixey; Laura Pastorelli; Laura Yates; Charlotte H Dean; Sara Wells; Wataru Satoh; Akihiko Shimono; Andy Greenfield
Sfrp1 and Sfrp2 are required for normal male sexual development in mice.
Developmental biology 2009;326(2):273-84.
2008: Lee Smith; John Willan; Nick Warr; Frances A Brook; Michael Cheeseman; Richard Sharpe; Pam Siggers; Andy Greenfield
The Maestro (Mro) gene is dispensable for normal sexual development and fertility in mice.
PloS one 2008;3(12):e4091.
2008: Clare Pritchard; Peter Underhill; Andy Greenfield
Using DNA microarrays.
Methods in molecular biology (Clifton, N.J.) 2008;461():605-29.
2006: Sam Cox; Lee Smith; Debora Bogani; Michael Cheeseman; Pam Siggers; Andy Greenfield
Sexually dimorphic expression of secreted frizzled-related (SFRP) genes in the developing mouse Müllerian duct.
Molecular reproduction and development 2006;73(8):1008-16.
2005: Debora Bogani; Catherine Willoughby; Jennifer Davies; Kulvinder Kaur; Ghazala Mirza; Anju Paudyal; Heather Haines; Richard McKeone; Matthew Cadman; Guido Pieles; Jürgen E Schneider; Shoumo Bhattacharya; Andrea Hardy; Patrick M Nolan; Nikos Tripodis; Michael J Depew; Ramya Chandrasekara; Gimara Duncan; Paul T Sharpe; Andy Greenfield; Paul Denny; Steve D M Brown; Jiannis Ragoussis; Ruth Arkell
Dissecting the genetic complexity of human 6p deletion syndromes by using a region-specific, phenotype-driven mouse screen.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(35):12477-82.
2005: Konstantinos Boulias; Nitsa Katrakili; Krister Bamberg; Peter Underhill; Andy Greenfield; Iannis Talianidis
Regulation of hepatic metabolic pathways by the orphan nuclear receptor SHP.
The EMBO journal 2005;24(14):2624-33.
2005: Thomas S Price; Regina Regan; Richard Mott; Asa Hedman; Ben Honey; Rachael J Daniels; Lee Smith; Andy Greenfield; Ana Tiganescu; Veronica Buckle; Nicki Ventress; Helena Ayyub; Anita Salhan; Susana Pedraza-Diaz; John Broxholme; Jiannis Ragoussis; Douglas R Higgs; Jonathan Flint; Samantha J L Knight
SW-ARRAY: a dynamic programming solution for the identification of copy-number changes in genomic DNA using array comparative genome hybridization data.
Nucleic acids research 2005;33(11):3455-64.
2004: Sarah C Webb; Anthony Attwood; Tony Brooks; Tom Freeman; Phil Gardner; Clare Pritchard; Debbie Williams; Peter Underhill; Mark A Strivens; Andy Greenfield; Ekaterina Pilicheva
LIMaS: the JAVA-based application and database for microarray experiment tracking.
Mammalian genome : official journal of the International Mammalian Genome Society 2004;15(9):740-7.
2004: Mohamed Mohideen Quwailid; Alison Hugill; Neil Dear; Lucie Vizor; Sara Wells; Emma Horner; Shelly Fuller; Jessica Weedon; Hamish McMath; Paul Woodman; David Edwards; David Campbell; Susan Rodger; Joanne Carey; Ann Roberts; Peter Glenister; Zuzanna Lalanne; Nick Parkinson; Emma L Coghill; Richard McKeone; Sam Cox; John Willan; Andy Greenfield; David A Keays; Saffron Brady; Nigel K Spurr; Ian C Gray; Jackie Hunter; Steve D M Brown; Roger D Cox
A gene-driven ENU-based approach to generating an allelic series in any gene.
Mammalian genome : official journal of the International Mammalian Genome Society 2004;15(8):585-91.
2004: Y Bacon; A Ooi; S Kerr; L Shaw-Andrews; L Winchester; S Breeds; Z Tymoska-Lalanne; J Clay; Andy Greenfield; P M Nolan
Screening for novel ENU-induced rhythm, entrainment and activity mutants.
Genes, brain, and behavior 2004;3(4):196-205.
2004: G Blanco; C Pritchard; P Underhill; S Breeds; K M F Townsend; Andy Greenfield; Steve D M Brown
Molecular phenotyping of the mouse ky mutant reveals UCP1 upregulation at the neuromuscular junctions of dystrophic soleus muscle.
Neuromuscular disorders : NMD 2004;14(3):217-28.
2003: Paul Elms; Pam Siggers; Diane Napper; Andy Greenfield; Ruth Arkell
Zic2 is required for neural crest formation and hindbrain patterning during mouse development.
Developmental biology 2003;264(2):391-406.
2003: Lee Smith; Nick Van Hateren; John Willan; Rosario Romero; Gonzalo Blanco; Pam Siggers; James Walsh; Ruby Banerjee; Paul Denny; Chris P Ponting; Andy Greenfield
Candidate testis-determining gene, Maestro (Mro), encodes a novel HEAT repeat protein.
Developmental dynamics : an official publication of the American Association of Anatomists 2003;227(4):600-7.
2003: Lee Smith; Peter Underhill; Clare Pritchard; Zuzanna Tymowska-Lalanne; Saba Abdul-Hussein; Helen Hilton; Laura Winchester; Deborah Williams; Tom Freeman; Sarah Webb; Andy Greenfield
Single primer amplification (SPA) of cDNA for microarray expression analysis.
Nucleic acids research 2003;31(3):e9.
2002: Pam Siggers; Lee Smith; Andy Greenfield
Sexually dimorphic expression of Gata-2 during mouse gonad development.
Mechanisms of development 2002;111(1-2):159-62.
2001: Sean M Grimmond; R Larder; Nick Van Hateren; Pam Siggers; S Morse; T Hacker; Ruth Arkell; Andy Greenfield
Expression of a novel mammalian epidermal growth factor-related gene during mouse neural development.
Mechanisms of development 2001;102(1-2):209-11.
2000: Sean M Grimmond; R Larder; Nick Van Hateren; Pam Siggers; T J Hulsebos; Ruth Arkell; Andy Greenfield
Cloning, mapping, and expression analysis of a gene encoding a novel mammalian EGF-related protein (SCUBE1).
Genomics 2000;70(1):74-81.
2000: Sean M Grimmond; Nick Van Hateren; Pam Siggers; Ruth Arkell; R Larder; MB Soares; M De Fatima Bonaldo; Lee Smith; Zuzanna Tymowska-Lalanne; C Wells; Andy Greenfield
Sexually dimorphic expression of protease nexin-1 and vanin-1 in the developing mouse gonad prior to overt differentiation suggests a role in mammalian sexual development.
Human molecular genetics 2000;9(10):1553-60.
1998: S Mazeyrat; N Saut; Carole A Sargent; Sean M Grimmond; guy Longepied; IE Ehrmann; PS Ellis; Andy Greenfield; Nabeel A Affara; Michael John Mitchell
The mouse Y chromosome interval necessary for spermatogonial proliferation is gene dense with syntenic homology to the human AZFa region.
Human molecular genetics 1998;7(11):1713-24.
1998: Andy Greenfield; Laura Carrel; David J Pennisi; C Philippe; NA Quaderi; Pam Siggers; K Steiner; P P Tam; Anthony P Monaco; Huntington F Willard; Peter Koopman
The UTX gene escapes X inactivation in mice and humans.
Human molecular genetics 1998;7(4):737-42.
1996: Andy Greenfield; D Scott; D Pennisi; I Ehrmann; P Ellis; L Cooper; Elizabeth Simpson; Peter Koopman
An H-YDb epitope is encoded by a novel mouse Y chromosome gene.
Nature genetics 1996;14(4):474-8.
1996: Andy Greenfield; T Dunn; George E O Muscat; Peter Koopman
The Sry-related gene Sox18 maps to distal mouse chromosome 2.
Genomics 1996;36(3):558-9.
1996: Andy Greenfield; Peter Koopman
SRY and mammalian sex determination.
Current topics in developmental biology 1996;34():1-23.
1995: Y W Jeske; J Bowles; Andy Greenfield; Peter Koopman
Expression of a linear Sry transcript in the mouse genital ridge.
Nature genetics 1995;10(4):480-2.
1995: E Wright; Murray Hargrave; J Christiansen; L Cooper; J Kun; T Evans; U Gangadharan; Andy Greenfield; Peter Koopman
The Sry-related gene Sox9 is expressed during chondrogenesis in mouse embryos.
Nature genetics 1995;9(1):15-20.