Paul Greengard

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Zhang Yun-wu; Liu Shijie; Zhang Xue; Li Wu-Bo; Chen Yaomin; Huang Xiumei; Sun Liangwu; Luo Wenjie; Netzer William J; Threadgill Richard; Wiegand Gordon; Wang Ruishan; Cohen Stanley N; Greengard Paul; Liao Francesca-Fang; Li Limin; Xu Huaxi
A Functional mouse retroposed gene Rps23r1 reduces Alzheimer's beta-amyloid levels and tau phosphorylation.
Hansen Christian; Howlin Jillian; Tengholm Anders; Dyachok Oleg; Vogel Wolfgang F; Nairn Angus C; Greengard Paul; Andersson Tommy
Wnt-5a-induced phosphorylation of DARPP-32 inhibits breast cancer cell migration in a CREB-dependent manner.
Rebholz Heike; Nishi Akinori; Liebscher Sabine; Nairn Angus C; Flajolet Marc; Greengard Paul
CK2 negatively regulates Galphas signaling.

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All Publications

2009: Zhang Yun-wu; Liu Shijie; Zhang Xue; Li Wu-Bo; Chen Yaomin; Huang Xiumei; Sun Liangwu; Luo Wenjie; Netzer William J; Threadgill Richard; Wiegand Gordon; Wang Ruishan; Cohen Stanley N; Greengard Paul; Liao Francesca-Fang; Li Limin; Xu Huaxi
A Functional mouse retroposed gene Rps23r1 reduces Alzheimer's beta-amyloid levels and tau phosphorylation.
Neuron 2009;64(3):328-40.
2009: Hansen Christian; Howlin Jillian; Tengholm Anders; Dyachok Oleg; Vogel Wolfgang F; Nairn Angus C; Greengard Paul; Andersson Tommy
Wnt-5a-induced phosphorylation of DARPP-32 inhibits breast cancer cell migration in a CREB-dependent manner.
The Journal of biological chemistry 2009;284(40):27533-43.
2009: Rebholz Heike; Nishi Akinori; Liebscher Sabine; Nairn Angus C; Flajolet Marc; Greengard Paul
CK2 negatively regulates Galphas signaling.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(33):14096-101.
2009: Bertran-Gonzalez Jesus; Håkansson Kerstin; Borgkvist Anders; Irinopoulou Theano; Brami-Cherrier Karen; Usiello Alessandro; Greengard Paul; Hervé Denis; Girault Jean-Antoine; Valjent Emmanuel; Fisone Gilberto
Histone H3 phosphorylation is under the opposite tonic control of dopamine D2 and adenosine A2A receptors in striatopallidal neurons.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2009;34(7):1710-20.
2009: Tekinay Ayse B; Nong Yi; Miwa Julie M; Lieberam Ivo; Ibanez-Tallon Ines; Greengard Paul; Heintz Nathaniel
A role for LYNX2 in anxiety-related behavior.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(11):4477-82.
2009: McAvoy Thomas; Zhou Ming-ming; Greengard Paul; Nairn Angus C
Phosphorylation of Rap1GAP, a striatally enriched protein, by protein kinase A controls Rap1 activity and dendritic spine morphology.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(9):3531-6.
2009: Endo Shogo; Shutoh Fumihiro; Dinh Tung Le; Okamoto Takehito; Ikeda Toshio; Suzuki Michiyuki; Kawahara Shigenori; Yanagihara Dai; Sato Yamato; Yamada Kazuyuki; Sakamoto Toshiro; Kirino Yutaka; Hartell Nicholas A; Yamaguchi Kazuhiko; Itohara Shigeyoshi; Nairn Angus C; Greengard Paul; Nagao Soichi; Ito Masao
Dual involvement of G-substrate in motor learning revealed by gene deletion.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(9):3525-30.
2009: Warner-Schmidt Jennifer L; Flajolet Marc; Maller Abigail; Chen Emily Y; Qi Hongshi; Svenningsson Per; Greengard Paul
Role of p11 in cellular and behavioral effects of 5-HT4 receptor stimulation.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2009;29(6):1937-46.
2009: Kim Yong; Teylan Merilee A; Baron Matthew; Sands Adam; Nairn Angus C; Greengard Paul
Methylphenidate-induced dendritic spine formation and DeltaFosB expression in nucleus accumbens.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(8):2915-20.
2009: Santini Emanuela; Alcacer Cristina; Cacciatore Silvia; Heiman Myriam; Hervé Denis; Greengard Paul; Girault Jean-Antoine; Valjent Emmanuel; Fisone Gilberto
L-DOPA activates ERK signaling and phosphorylates histone H3 in the striatonigral medium spiny neurons of hemiparkinsonian mice.
Journal of neurochemistry 2009;108(3):621-33.
2009: da Cruz e Silva Odete A B; Rebelo Sandra; Vieira Sandra I; Gandy Sam; da Cruz e Silva Edgar F; Greengard Paul
Enhanced generation of Alzheimer's amyloid-beta following chronic exposure to phorbol ester correlates with differential effects on alpha and epsilon isozymes of protein kinase C.
Journal of neurochemistry 2009;108(2):319-30.
2009: Santini Emanuela; Heiman Myriam; Greengard Paul; Valjent Emmanuel; Fisone Gilberto
Inhibition of mTOR signaling in Parkinson's disease prevents L-DOPA-induced dyskinesia.
Science signaling 2009;2(80):ra36.
2008: Flajolet Marc; Wang Zhongfeng; Futter Marie; Shen Weixing; Nuangchamnong Nina; Bendor Jacob; Wallach Iwona; Nairn Angus C; Surmeier D James; Greengard Paul
FGF acts as a co-transmitter through adenosine A(2A) receptor to regulate synaptic plasticity.
Nature neuroscience 2008;11(12):1402-9.
2008: Meyer Douglas A; Richer Edmond; Benkovic Stanley A; Hayashi Kanehiro; Kansy Janice W; Hale Carly F; Moy Lily Y; Kim Yong; O'Callaghan James P; Tsai Li-Huei; Greengard Paul; Nairn Angus C; Cowan Christopher W; Miller Diane B; Antich Pietro; Bibb James A
Striatal dysregulation of Cdk5 alters locomotor responses to cocaine, motor learning, and dendritic morphology.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(47):18561-6.
2008: Lagace Diane C; Benavides David R; Kansy Janice W; Mapelli Marina; Greengard Paul; Bibb James A; Eisch Amelia J
Cdk5 is essential for adult hippocampal neurogenesis.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(47):18567-71.
2008: Doyle Joseph P; Dougherty Joseph D; Heiman Myriam; Schmidt Eric F; Stevens Tanya R; Ma Guojun; Bupp Sujata; Shrestha Prerana; Shah Rajiv D; Doughty Martin L; Gong Shiaoching; Greengard Paul; Heintz Nathaniel
Application of a translational profiling approach for the comparative analysis of CNS cell types.
Cell 2008;135(4):749-62.
2008: Heiman Myriam; Schaefer Anne; Gong Shiaoching; Peterson Jayms D; Day Michelle; Ramsey Keri E; Suárez-Fariñas Mayte; Schwarz Cordelia; Stephan Dietrich A; Surmeier D James; Greengard Paul; Heintz Nathaniel
A translational profiling approach for the molecular characterization of CNS cell types.
Cell 2008;135(4):738-48.
2008: Gitler Daniel; Cheng Qing; Greengard Paul; Augustine George J
Synapsin IIa controls the reserve pool of glutamatergic synaptic vesicles.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2008;28(43):10835-43.
2008: Nishi Akinori; Kuroiwa Mahomi; Miller Diane B; O'Callaghan James P; Bateup Helen S; Shuto Takahide; Sotogaku Naoki; Fukuda Takaichi; Heintz Nathaniel; Greengard Paul; Snyder Gretchen L
Distinct roles of PDE4 and PDE10A in the regulation of cAMP/PKA signaling in the striatum.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2008;28(42):10460-71.
2008: Oumata Nassima; Bettayeb Karima; Ferandin Yoan; Demange Luc; Lopez-Giral Angela; Goddard Marie-Lorène; Myrianthopoulos Vassilios; Mikros Emmanuel; Flajolet Marc; Greengard Paul; Meijer Laurent; Galons Hervé
Roscovitine-derived, dual-specificity inhibitors of cyclin-dependent kinases and casein kinases 1.
Journal of medicinal chemistry 2008;51(17):5229-42.
2008: Pulipparacharuvil Suprabha; Renthal William; Hale Carly F; Taniguchi Makoto; Xiao Guanghua; Kumar Arvind; Russo Scott J; Sikder Devanjan; Dewey Colleen M; Davis Maya M; Greengard Paul; Nairn Angus C; Nestler Eric J; Cowan Christopher W
Cocaine regulates MEF2 to control synaptic and behavioral plasticity.
Neuron 2008;59(4):621-33.
2008: Shen Weixing; Flajolet Marc; Greengard Paul; Surmeier D James
Dichotomous dopaminergic control of striatal synaptic plasticity.
Science (New York, N.Y.) 2008;321(5890):848-51.
2008: Bateup Helen S; Svenningsson Per; Kuroiwa Mahomi; Gong Shiaoching; Nishi Akinori; Heintz Nathaniel; Greengard Paul
Cell type-specific regulation of DARPP-32 phosphorylation by psychostimulant and antipsychotic drugs.
Nature neuroscience 2008;11(8):932-9.
2008: Stipanovich Alexandre; Valjent Emmanuel; Matamales Miriam; Nishi Akinori; Ahn Jung-Hyuck; Maroteaux Matthieu; Bertran-Gonzalez Jesus; Brami-Cherrier Karen; Enslen Hervé; Corbillé Anne-Gaëlle; Filhol Odile; Nairn Angus C; Greengard Paul; Hervé Denis; Girault Jean-Antoine
A phosphatase cascade by which rewarding stimuli control nucleosomal response.
Nature 2008;453(7197):879-84.
2008: Muly E Chris; Nairn Angus C; Greengard Paul; Rainnie Donald G
Subcellular distribution of the Rho-GEF Lfc in primate prefrontal cortex: effect of neuronal activation.
The Journal of comparative neurology 2008;508(6):927-39.
2008: O'Sullivan Gerard J; Dunleavy Mark; Hakansson Kerstin; Clementi Mario; Kinsella Anthony; Croke David T; Drago John; Fienberg Allen A; Greengard Paul; Sibley David R; Fisone Gilberto; Henshall David C; Waddington John L
Dopamine D1 vs D5 receptor-dependent induction of seizures in relation to DARPP-32, ERK1/2 and GluR1-AMPA signalling.
Neuropharmacology 2008;54(7):1051-61.
2008: Charlton Joanna J; Allen Patrick B; Psifogeorgou Kassi; Chakravarty Sumana; Gomes Ivone; Neve Rachael L; Devi Lakshmi A; Greengard Paul; Nestler Eric J; Zachariou Venetia
Multiple actions of spinophilin regulate mu opioid receptor function.
Neuron 2008;58(2):238-47.
2008: Kao Hung-Teh; Li Ping; Chao Helen M; Janoschka Stephen; Pham Kara; Feng Jian; Mcewen Bruce S; Greengard Paul; Pieribone Vincent A; Porton Barbara
Early involvement of synapsin III in neural progenitor cell development in the adult hippocampus.
The Journal of comparative neurology 2008;507(6):1860-70.
2008: Sung Jee Young; Engmann Olivia; Teylan Merilee A; Nairn Angus C; Greengard Paul; Kim Yong
WAVE1 controls neuronal activity-induced mitochondrial distribution in dendritic spines.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(8):3112-6.
2008: Zhang Xiaoqun; Andren Per E; Greengard Paul; Svenningsson Per
Evidence for a role of the 5-HT1B receptor and its adaptor protein, p11, in L-DOPA treatment of an animal model of Parkinsonism.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(6):2163-8.
2008: Borgkvist Anders; Marcellino Daniel; Fuxe Kjell; Greengard Paul; Fisone Gilberto
Regulation of DARPP-32 phosphorylation by Delta9-tetrahydrocannabinol.
Neuropharmacology 2008;54(1):31-5.
2007: Svenningsson Per; Bateup Helen; Qi Hongshi; Takamiya Kogo; Huganir Richard L; Spedding Michael; Roth Bryan L; McEwen Bruce S; Greengard Paul
Involvement of AMPA receptor phosphorylation in antidepressant actions with special reference to tianeptine.
The European journal of neuroscience 2007;26(12):3509-17.
2007: Barbano Paolo E; Spivak Marina; Flajolet Marc; Nairn Angus C; Greengard Paul; Greengard Leslie
A mathematical tool for exploring the dynamics of biological networks.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(49):19169-74.
2007: Kitaoka Shiho; Furuyashiki Tomoyuki; Nishi Akinori; Shuto Takahide; Koyasu Sho; Matsuoka Toshiyuki; Miyasaka Masayuki; Greengard Paul; Narumiya Shuh
Prostaglandin E2 acts on EP1 receptor and amplifies both dopamine D1 and D2 receptor signaling in the striatum.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2007;27(47):12900-7.
2007: Borgkvist Anders; Usiello Alessandro; Greengard Paul; Fisone Gilberto
Activation of the cAMP/PKA/DARPP-32 signaling pathway is required for morphine psychomotor stimulation but not for morphine reward.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2007;32(9):1995-2003.
2007: Schaefer Anne; O'Carroll Dónal; Tan Chan Lek; Hillman Dean; Sugimori Mutsuyuki; Llinas Rodolfo; Greengard Paul
Cerebellar neurodegeneration in the absence of microRNAs.
The Journal of experimental medicine 2007;204(7):1553-8.
2007: Hawasli Ammar H; Benavides David R; Nguyen Chan; Kansy Janice W; Hayashi Kanehiro; Chambon Pierre; Greengard Paul; Powell Craig M; Cooper Donald C; Bibb James A
Cyclin-dependent kinase 5 governs learning and synaptic plasticity via control of NMDAR degradation.
Nature neuroscience 2007;10(7):880-6.
2007: Santini Emanuela; Valjent Emmanuel; Usiello Alessandro; Carta Manolo; Borgkvist Anders; Girault Jean-Antoine; Hervé Denis; Greengard Paul; Fisone Gilberto
Critical involvement of cAMP/DARPP-32 and extracellular signal-regulated protein kinase signaling in L-DOPA-induced dyskinesia.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2007;27(26):6995-7005.
2007: Siksou Léa; Rostaing Philippe; Lechaire Jean-Pierre; Boudier Thomas; Ohtsuka Toshihisa; Fejtová Anna; Kao Hung-Teh; Greengard Paul; Gundelfinger Eckart D; Triller Antoine; Marty Serge
Three-dimensional architecture of presynaptic terminal cytomatrix.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2007;27(26):6868-77.
2007: Ahn Jung-Hyuck; Sung Jee Young; McAvoy Thomas; Nishi Akinori; Janssens Veerle; Goris Jozef; Greengard Paul; Nairn Angus C
The B''/PR72 subunit mediates Ca2+-dependent dephosphorylation of DARPP-32 by protein phosphatase 2A.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(23):9876-81.
2007: Wang Xinhua; Zeng Weizhong; Kim Min Seuk; Allen Patrick B; Greengard Paul; Muallem Shmuel
Spinophilin/neurabin reciprocally regulate signaling intensity by G protein-coupled receptors.
The EMBO journal 2007;26(11):2768-76.
2007: Luo Wenjie; Dou Fei; Rodina Anna; Chip Sophorn; Kim Joungnam; Zhao Qi; Moulick Kamalika; Aguirre Julia; Wu Nian; Greengard Paul; Chiosis Gabriela
Roles of heat-shock protein 90 in maintaining and facilitating the neurodegenerative phenotype in tauopathies.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(22):9511-6.
2007: Sahlin Charlotte; Lord Anna; Magnusson Kristina; Englund Hillevi; Almeida Claudia G; Greengard Paul; Nyberg Fred; Gouras Gunnar K; Lannfelt Lars; Nilsson Lars N G
The Arctic Alzheimer mutation favors intracellular amyloid-beta production by making amyloid precursor protein less available to alpha-secretase.
Journal of neurochemistry 2007;101(3):854-62.
2007: Svenningsson Per; Tzavara Eleni T; Qi Hongshi; Carruthers Robert; Witkin Jeffrey M; Nomikos George G; Greengard Paul
Biochemical and behavioral evidence for antidepressant-like effects of 5-HT6 receptor stimulation.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2007;27(15):4201-9.
2007: Flajolet Marc; He Gen; Heiman Myriam; Lin Angie; Nairn Angus C; Greengard Paul
Regulation of Alzheimer's disease amyloid-beta formation by casein kinase I.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(10):4159-64.
2007: Ahn Jung-Hyuck; McAvoy Thomas; Rakhilin Sergey V; Nishi Akinori; Greengard Paul; Nairn Angus C
Protein kinase A activates protein phosphatase 2A by phosphorylation of the B56delta subunit.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(8):2979-84.
2007: Svenningsson Per; Greengard Paul
p11 (S100A10)--an inducible adaptor protein that modulates neuronal functions.
Current opinion in pharmacology 2007;7(1):27-32.
2006: Hansen Christian; Greengard Paul; Nairn Angus C; Andersson Tommy; Vogel Wolfgang F
Phosphorylation of DARPP-32 regulates breast cancer cell migration downstream of the receptor tyrosine kinase DDR1.
Experimental cell research 2006;312(20):4011-8.
2006: Liu Wenhua; Yuen Eunice Y; Allen Patrick B; Feng Jian; Greengard Paul; Yan Zhen
Adrenergic modulation of NMDA receptors in prefrontal cortex is differentially regulated by RGS proteins and spinophilin.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(48):18338-43.
2006: Aperia Anita; Greengard Paul
Dopamine receptor response to NMDA stimulation.
The American journal of psychiatry 2006;163(10):1682.
2006: Ehrman L A; Williams M T; Schaefer T L; Gudelsky G A; Reed T M; Fienberg A A; Greengard P; Vorhees C V
Phosphodiesterase 1B differentially modulates the effects of methamphetamine on locomotor activity and spatial learning through DARPP32-dependent pathways: evidence from PDE1B-DARPP32 double-knockout mice.
Genes, brain, and behavior 2006;5(7):540-51.
2006: Yan Lily; Bobula Jessica M; Svenningsson Per; Greengard Paul; Silver Rae
DARPP-32 involvement in the photic pathway of the circadian system.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2006;26(37):9434-8.
2006: Kim Yong; Sung Jee Young; Ceglia Ilaria; Lee Ko-Woon; Ahn Jung-Hyuck; Halford Jonathan M; Kim Amie M; Kwak Seung P; Park Jong Bae; Ho Ryu Sung; Schenck Annette; Bardoni Barbara; Scott John D; Nairn Angus C; Greengard Paul
Phosphorylation of WAVE1 regulates actin polymerization and dendritic spine morphology.
Nature 2006;442(7104):814-7.
2006: Yabuuchi K; Kuroiwa M; Shuto T; Sotogaku N; Snyder G L; Higashi H; Tanaka M; Greengard P; Nishi A
Role of adenosine A1 receptors in the modulation of dopamine D1 and adenosine A2A receptor signaling in the neostriatum.
Neuroscience 2006;141(1):19-25.
2006: Allen P B; Zachariou V; Svenningsson P; Lepore A C; Centonze D; Costa C; Rossi S; Bender G; Chen G; Feng J; Snyder G L; Bernardi G; Nestler E J; Yan Z; Calabresi P; Greengard P
Distinct roles for spinophilin and neurabin in dopamine-mediated plasticity.
Neuroscience 2006;140(3):897-911.
2006: Venton B Jill; Seipel Andrew T; Phillips Paul E M; Wetsel William C; Gitler Daniel; Greengard Paul; Augustine George J; Wightman R Mark
Cocaine increases dopamine release by mobilization of a synapsin-dependent reserve pool.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2006;26(12):3206-9.
2006: Zhang Y; Svenningsson P; Picetti R; Schlussman S D; Nairn A C; Ho A; Greengard P; Kreek M J
Cocaine self-administration in mice is inversely related to phosphorylation at Thr34 (protein kinase A site) and Ser130 (kinase CK1 site) of DARPP-32.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2006;26(10):2645-51.
2006: Rogers Jessica P; Beuscher Albert E; Flajolet Marc; McAvoy Thomas; Nairn Angus C; Olson Arthur J; Greengard Paul
Discovery of protein phosphatase 2C inhibitors by virtual screening.
Journal of medicinal chemistry 2006;49(5):1658-67.
2006: Zachariou Venetia; Sgambato-Faure Véronique; Sasaki Teresa; Svenningsson Per; Berton Olivier; Fienberg Allen A; Nairn Angus C; Greengard Paul; Nestler Eric J
Phosphorylation of DARPP-32 at Threonine-34 is required for cocaine action.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2006;31(3):555-62.
2006: Lee Ko-Woon; Kim Yong; Kim Amie M; Helmin Kathryn; Nairn Angus C; Greengard Paul
Cocaine-induced dendritic spine formation in D1 and D2 dopamine receptor-containing medium spiny neurons in nucleus accumbens.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(9):3399-404.
2006: Cai Dongming; Netzer William J; Zhong Minghao; Lin Yixin; Du Guangwei; Frohman Michael; Foster David A; Sisodia Sangram S; Xu Huaxi; Gorelick Fred S; Greengard Paul
Presenilin-1 uses phospholipase D1 as a negative regulator of beta-amyloid formation.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(6):1941-6.
2006: Cai Dongming; Zhong Minghao; Wang Runsheng; Netzer William J; Shields Dennis; Zheng Hui; Sisodia Sangram S; Foster David A; Gorelick Fred S; Xu Huaxi; Greengard Paul
Phospholipase D1 corrects impaired betaAPP trafficking and neurite outgrowth in familial Alzheimer's disease-linked presenilin-1 mutant neurons.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(6):1936-40.
2006: Scott Lena; Zelenin Sergey; Malmersjö Seth; Kowalewski Jacob M; Markus Eivor Zettergren; Nairn Angus C; Greengard Paul; Brismar Hjalmar; Aperia Anita
Allosteric changes of the NMDA receptor trap diffusible dopamine 1 receptors in spines.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(3):762-7.
2006: Svenningsson Per; Chergui Karima; Rachleff Ilan; Flajolet Marc; Zhang Xiaoqun; El Yacoubi Malika; Vaugeois Jean-Marie; Nomikos George G; Greengard Paul
Alterations in 5-HT1B receptor function by p11 in depression-like states.
Science (New York, N.Y.) 2006;311(5757):77-80.
2006: Håkansson Kerstin; Galdi Stacey; Hendrick Joseph; Snyder Gretchen; Greengard Paul; Fisone Gilberto
Regulation of phosphorylation of the GluR1 AMPA receptor by dopamine D2 receptors.
Journal of neurochemistry 2006;96(2):482-8.
2005: Jin Mi; Bateup Helen; Padovan Júlio C; Greengard Paul; Nairn Angus C; Chait Brian T
Quantitative analysis of protein phosphorylation in mouse brain by hypothesis-driven multistage mass spectrometry.
Analytical chemistry 2005;77(24):7845-51.
2005: Uematsu Ken; Futter Marie; Hsieh-Wilson Linda C; Higashi Hideho; Maeda Hisao; Nairn Angus C; Greengard Paul; Nishi Akinori
Regulation of spinophilin Ser94 phosphorylation in neostriatal neurons involves both DARPP-32-dependent and independent pathways.
Journal of neurochemistry 2005;95(6):1642-52.
2005: Bordelon Jill R; Smith Yoland; Nairn Angus C; Colbran Roger J; Greengard Paul; Muly E Chris
Differential localization of protein phosphatase-1alpha, beta and gamma1 isoforms in primate prefrontal cortex.
Cerebral cortex (New York, N.Y. : 1991) 2005;15(12):1928-37.
2005: Almeida Claudia G; Tampellini Davide; Takahashi Reisuke H; Greengard Paul; Lin Michael T; Snyder Eric M; Gouras Gunnar K
Beta-amyloid accumulation in APP mutant neurons reduces PSD-95 and GluR1 in synapses.
Neurobiology of disease 2005;20(2):187-98.
2005: Hamada Miho; Hendrick Joseph P; Ryan Gregory R; Kuroiwa Mahomi; Higashi Hideho; Tanaka Masatoshi; Nairn Angus C; Greengard Paul; Nishi Akinori
Nicotine regulates DARPP-32 (dopamine- and cAMP-regulated phosphoprotein of 32 kDa) phosphorylation at multiple sites in neostriatal neurons.
The Journal of pharmacology and experimental therapeutics 2005;315(2):872-8.
2005: Andersson Mikael; Usiello Alessandro; Borgkvist Anders; Pozzi Laura; Dominguez Cecilia; Fienberg Allen A; Svenningsson Per; Fredholm Bertil B; Borrelli Emiliana; Greengard Paul; Fisone Gilberto
Cannabinoid action depends on phosphorylation of dopamine- and cAMP-regulated phosphoprotein of 32 kDa at the protein kinase A site in striatal projection neurons.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2005;25(37):8432-8.
2005: Snyder Eric M; Nong Yi; Almeida Claudia G; Paul Surojit; Moran Timothy; Choi Eun Young; Nairn Angus C; Salter Michael W; Lombroso Paul J; Gouras Gunnar K; Greengard Paul
Regulation of NMDA receptor trafficking by amyloid-beta.
Nature neuroscience 2005;8(8):1051-8.
2005: Chergui Karima; Svenningsson Per; Greengard Paul
Physiological role for casein kinase 1 in glutamatergic synaptic transmission.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2005;25(28):6601-9.
2005: Ryan Xiaozhou P; Alldritt Jacqueline; Svenningsson Per; Allen Patrick B; Wu Gang-Yi; Nairn Angus C; Greengard Paul
The Rho-specific GEF Lfc interacts with neurabin and spinophilin to regulate dendritic spine morphology.
Neuron 2005;47(1):85-100.
2005: Stenh Charlotte; Englund Hillevi; Lord Anna; Johansson Ann-Sofi; Almeida Claudia G; Gellerfors Pär; Greengard Paul; Gouras Gunnar K; Lannfelt Lars; Nilsson Lars N G
Amyloid-beta oligomers are inefficiently measured by enzyme-linked immunosorbent assay.
Annals of neurology 2005;58(1):147-50.
2005: Brady Ashley E; Wang Qin; Allen Patrick B; Rizzo Mark; Greengard Paul; Limbird Lee E
Alpha 2-adrenergic agonist enrichment of spinophilin at the cell surface involves beta gamma subunits of Gi proteins and is preferentially induced by the alpha 2A-subtype.
Molecular pharmacology 2005;67(5):1690-6.
2005: Wang Xinhua; Zeng Weizhong; Soyombo Abigail A; Tang Wei; Ross Elliott M; Barnes Anthony P; Milgram Sharon L; Penninger Josef M; Allen Patrick B; Greengard Paul; Muallem Shmuel
Spinophilin regulates Ca2+ signalling by binding the N-terminal domain of RGS2 and the third intracellular loop of G-protein-coupled receptors.
Nature cell biology 2005;7(4):405-11.
2005: Hilfiker Sabine; Benfenati Fabio; Doussau Frédéric; Nairn Angus C; Czernik Andrew J; Augustine George J; Greengard Paul
Structural domains involved in the regulation of transmitter release by synapsins.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2005;25(10):2658-69.
2005: Futter Marie; Uematsu Ken; Bullock Stewart A; Kim Yong; Hemmings Hugh C; Nishi Akinori; Greengard Paul; Nairn Angus C
Phosphorylation of spinophilin by ERK and cyclin-dependent PK 5 (Cdk5).
Proceedings of the National Academy of Sciences of the United States of America 2005;102(9):3489-94.
2005: Takahashi Satoru; Ohshima Toshio; Cho Andrew; Sreenath Taduru; Iadarola Michael J; Pant Harish C; Kim Yong; Nairn Angus C; Brady Roscoe O; Greengard Paul; Kulkarni Ashok B
Increased activity of cyclin-dependent kinase 5 leads to attenuation of cocaine-mediated dopamine signaling.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(5):1737-42.
2005: Nishi Akinori; Watanabe Yasuo; Higashi Hideho; Tanaka Masatoshi; Nairn Angus C; Greengard Paul
Glutamate regulation of DARPP-32 phosphorylation in neostriatal neurons involves activation of multiple signaling cascades.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(4):1199-204.
2005: Valjent Emmanuel; Pascoli Vincent; Svenningsson Per; Paul Surojit; Enslen Hervé; Corvol Jean-Christophe; Stipanovich Alexandre; Caboche Jocelyne; Lombroso Paul J; Nairn Angus C; Greengard Paul; Hervé Denis; Girault Jean-Antoine
Regulation of a protein phosphatase cascade allows convergent dopamine and glutamate signals to activate ERK in the striatum.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(2):491-6.
2005: Svenningsson Per; Nairn Angus C; Greengard Paul
DARPP-32 mediates the actions of multiple drugs of abuse.
The AAPS journal 2005;7(2):E353-60.
2004: Gitler Daniel; Takagishi Yoshiko; Feng Jian; Ren Yong; Rodriguiz Ramona M; Wetsel William C; Greengard Paul; Augustine George J
Different presynaptic roles of synapsins at excitatory and inhibitory synapses.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2004;24(50):11368-80.
2004: Muly E Chris; Allen Patrick; Mazloom Maney; Aranbayeva Zina; Greenfield Audrey T; Greengard Paul
Subcellular distribution of neurabin immunolabeling in primate prefrontal cortex: comparison with spinophilin.
Cerebral cortex (New York, N.Y. : 1991) 2004;14(12):1398-407.
2004: Ouimet Charles C; Katona István; Allen Patrick; Freund Tamás F; Greengard Paul
Cellular and subcellular distribution of spinophilin, a PP1 regulatory protein that bundles F-actin in dendritic spines.
The Journal of comparative neurology 2004;479(4):374-88.
2004: Rakhilin S V; Olson P A; Nishi A; Starkova N N; Fienberg A A; Nairn A C; Surmeier D J; Greengard P
A network of control mediated by regulator of calcium/calmodulin-dependent signaling.
Science (New York, N.Y.) 2004;306(5696):698-701.
2004: Giovedì Silvia; Darchen François; Valtorta Flavia; Greengard Paul; Benfenati Fabio
Synapsin is a novel Rab3 effector protein on small synaptic vesicles. II. Functional effects of the Rab3A-synapsin I interaction.
The Journal of biological chemistry 2004;279(42):43769-79.
2004: Giovedì Silvia; Vaccaro Paola; Valtorta Flavia; Darchen François; Greengard Paul; Cesareni Gianni; Benfenati Fabio
Synapsin is a novel Rab3 effector protein on small synaptic vesicles. I. Identification and characterization of the synapsin I-Rab3 interactions in vitro and in intact nerve terminals.
The Journal of biological chemistry 2004;279(42):43760-8.
2004: Meijer Laurent; Flajolet Marc; Greengard Paul
Pharmacological inhibitors of glycogen synthase kinase 3.
Trends in pharmacological sciences 2004;25(9):471-80.
2004: Mayerhofer A; Fritz S; Mani S; Rajendra Kumar T; Thalhammer A; Ingrassia P; Fienberg A A; Greengard P
Ovarian function and morphology after deletion of the DARPP-32 gene in mice.
Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 2004;112(8):451-7.
2004: Hamada Miho; Higashi Hideho; Nairn Angus C; Greengard Paul; Nishi Akinori
Differential regulation of dopamine D1 and D2 signaling by nicotine in neostriatal neurons.
Journal of neurochemistry 2004;90(5):1094-103.
2004: Wang Hong; Luo Wen-Jie; Zhang Yun-Wu; Li Yue-Ming; Thinakaran Gopal; Greengard Paul; Xu Huaxi
Presenilins and gamma-secretase inhibitors affect intracellular trafficking and cell surface localization of the gamma-secretase complex components.
The Journal of biological chemistry 2004;279(39):40560-6.
2004: Nally Rachel E; Kinsella Anthony; Tighe Orna; Croke David T; Fienberg Allen A; Greengard Paul; Waddington John L
Ethologically based resolution of D2-like dopamine receptor agonist-versus antagonist-induced behavioral topography in dopamine- and adenosine 3',5'-monophosphate-regulated phosphoprotein of 32 kDa "knockout" mutants congenic on the C57BL/6 genetic background.
The Journal of pharmacology and experimental therapeutics 2004;310(3):1281-7.
2004: Grossman Stacie D; Futter Marie; Snyder Gretchen L; Allen Patrick B; Nairn Angus C; Greengard Paul; Hsieh-Wilson Linda C
Spinophilin is phosphorylated by Ca2+/calmodulin-dependent protein kinase II resulting in regulation of its binding to F-actin.
Journal of neurochemistry 2004;90(2):317-24.
2004: Wang Qin; Zhao Jiali; Brady Ashley E; Feng Jian; Allen Patrick B; Lefkowitz Robert J; Greengard Paul; Limbird Lee E
Spinophilin blocks arrestin actions in vitro and in vivo at G protein-coupled receptors.
Science (New York, N.Y.) 2004;304(5679):1940-4.
2004: Girault Jean-Antoine; Greengard Paul
The neurobiology of dopamine signaling.
Archives of neurology 2004;61(5):641-4.
2004: Allen Patrick B; Greenfield Audrey T; Svenningsson Per; Haspeslagh Derek C; Greengard Paul
Phactrs 1-4: A family of protein phosphatase 1 and actin regulatory proteins.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(18):7187-92.
2004: Knockaert Marie; Blondel Marc; Bach Stéphane; Leost Maryse; Elbi Cem; Hager Gordon L; Nagy Scott R; Han Dalho; Denison Michael; Ffrench Martine; Ryan Xiaozhou P; Magiatis Prokopios; Polychronopoulos Panos; Greengard Paul; Skaltsounis Leandros; Meijer Laurent
Independent actions on cyclin-dependent kinases and aryl hydrocarbon receptor mediate the antiproliferative effects of indirubins.
Oncogene 2004;23(25):4400-12.
2004: Gitler Daniel; Xu Yimei; Kao Hung-Teh; Lin Dayu; Lim Sangmi; Feng Jian; Greengard Paul; Augustine George J
Molecular determinants of synapsin targeting to presynaptic terminals.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2004;24(14):3711-20.
2004: Lin Ta-Hsien; Huang Yi-Choang; Chin Mei-ling; Chen Yi-chen; Jeng Hao-Hsuan; Lin Fang-Min; Shiao Ming-Shi; Horiuchi Atsuko; Greengard Paul; Nairn Angus C; Huang Hsien-bin
1H, 15N, and 13C resonance assignments of DARPP-32 (dopamine and cAMP-regulated phosphoprotein, Mr. 32,000)--a protein inhibitor of protein phosphatase-1.
Journal of biomolecular NMR 2004;28(4):413-4.
2004: Chen Guojun; Greengard Paul; Yan Zhen
Potentiation of NMDA receptor currents by dopamine D1 receptors in prefrontal cortex.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(8):2596-600.
2004: Chergui Karima; Svenningsson Per; Greengard Paul
Cyclin-dependent kinase 5 regulates dopaminergic and glutamatergic transmission in the striatum.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(7):2191-6.
2004: Li Chenjian; Brake Wayne G; Romeo Russell D; Dunlop John C; Gordon Marisa; Buzescu Rodica; Magarinos Ana Maria; Allen Patrick B; Greengard Paul; Luine Victoria; McEwen Bruce S
Estrogen alters hippocampal dendritic spine shape and enhances synaptic protein immunoreactivity and spatial memory in female mice.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(7):2185-90.
2004: Polychronopoulos Panagiotis; Magiatis Prokopios; Skaltsounis Alexios-Leandros; Myrianthopoulos Vassilios; Mikros Emmanuel; Tarricone Aldo; Musacchio Andrea; Roe S Mark; Pearl Laurence; Leost Maryse; Greengard Paul; Meijer Laurent
Structural basis for the synthesis of indirubins as potent and selective inhibitors of glycogen synthase kinase-3 and cyclin-dependent kinases.
Journal of medicinal chemistry 2004;47(4):935-46.
2004: Tang Yong; Janssen William G M; Hao Jiandong; Roberts Jeffrey A; McKay Heather; Lasley Bill; Allen Patrick B; Greengard Paul; Rapp Peter R; Kordower Jeffrey H; Hof Patrick R; Morrison John H
Estrogen replacement increases spinophilin-immunoreactive spine number in the prefrontal cortex of female rhesus monkeys.
Cerebral cortex (New York, N.Y. : 1991) 2004;14(2):215-23.
2004: Muly E Chris; Smith Yoland; Allen Patrick; Greengard Paul
Subcellular distribution of spinophilin immunolabeling in primate prefrontal cortex: localization to and within dendritic spines.
The Journal of comparative neurology 2004;469(2):185-97.
2004: Sato Noboru; Meijer Laurent; Skaltsounis Leandros; Greengard Paul; Brivanlou Ali H
Maintenance of pluripotency in human and mouse embryonic stem cells through activation of Wnt signaling by a pharmacological GSK-3-specific inhibitor.
Nature medicine 2004;10(1):55-63.
2004: Nairn Angus C; Svenningsson Per; Nishi Akinori; Fisone Gilberto; Girault Jean-Antoine; Greengard Paul
The role of DARPP-32 in the actions of drugs of abuse.
Neuropharmacology 2004;47 Suppl 1():14-23.
2004: Lee S J; Romeo R D; Svenningsson P; Campomanes C R; Allen P B; Greengard P; McEwen B S
Estradiol affects spinophilin protein differently in gonadectomized males and females.
Neuroscience 2004;127(4):983-8.
2004: Svenningsson Per; Nishi Akinori; Fisone Gilberto; Girault Jean-Antoine; Nairn Angus C; Greengard Paul
DARPP-32: an integrator of neurotransmission.
Annual review of pharmacology and toxicology 2004;44():269-96.
2003: Fukui Ryuichi; Svenningsson Per; Matsuishi Toyojiro; Higashi Hideho; Nairn Angus C; Greengard Paul; Nishi Akinori
Effect of methylphenidate on dopamine/DARPP signalling in adult, but not young, mice.
Journal of neurochemistry 2003;87(6):1391-401.
2003: Meijer Laurent; Skaltsounis Alexios-Leandros; Magiatis Prokopios; Polychronopoulos Panagiotis; Knockaert Marie; Leost Maryse; Ryan Xiaozhou P; Vonica Claudia Alin; Brivanlou Ali; Dajani Rana; Crovace Claudia; Tarricone Cataldo; Musacchio Andrea; Roe S Mark; Pearl Laurence; Greengard Paul
GSK-3-selective inhibitors derived from Tyrian purple indirubins.
Chemistry & biology 2003;10(12):1255-66.
2003: Flajolet Marc; Rakhilin Sergey; Wang Hong; Starkova Natalia; Nuangchamnong Nina; Nairn Angus C; Greengard Paul
Protein phosphatase 2C binds selectively to and dephosphorylates metabotropic glutamate receptor 3.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(26):16006-11.
2003: Nally Rachel E; McNamara Fergal N; Clifford Jeremiah J; Kinsella A; Tighe Orna; Croke David T; Fienberg Allen A; Greengard Paul; Waddington John L
Topographical Assessment of Ethological and Dopamine Receptor Agonist-Induced Behavioral Phenotype in Mutants with Congenic DARPP-32 'Knockout'.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2003;28(12):2055-63.
2003: Svenningsson Per; Tzavara Eleni T; Carruthers Robert; Rachleff Ilan; Wattler Sigrid; Nehls Michael; McKinzie David L; Fienberg Allen A; Nomikos George G; Greengard Paul
Diverse psychotomimetics act through a common signaling pathway.
Science (New York, N.Y.) 2003;302(5649):1412-5.
2003: Snyder Gretchen L; Galdi Stacey; Fienberg Allen A; Allen Patrick; Nairn Angus C; Greengard Paul
Regulation of AMPA receptor dephosphorylation by glutamate receptor agonists.
Neuropharmacology 2003;45(6):703-13.
2003: Netzer William J; Dou Fei; Cai Dongming; Veach Darren; Jean Stephanie; Li Yueming; Bornmann William G; Clarkson Bayard; Xu Huaxi; Greengard Paul
Gleevec inhibits beta-amyloid production but not Notch cleavage.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(21):12444-9.
2003: Hao Jiandong; Janssen William G M; Tang Yong; Roberts Jeffrey A; McKay Heather; Lasley Bill; Allen Patrick B; Greengard Paul; Rapp Peter R; Kordower Jeffrey H; Hof Patrick R; Morrison John H
Estrogen increases the number of spinophilin-immunoreactive spines in the hippocampus of young and aged female rhesus monkeys.
The Journal of comparative neurology 2003;465(4):540-50.
2003: Brady Ashley E; Wang Qin; Colbran Roger J; Allen Patrick B; Greengard Paul; Limbird Lee E
Spinophilin stabilizes cell surface expression of alpha 2B-adrenergic receptors.
The Journal of biological chemistry 2003;278(34):32405-12.
2003: Pozzi Laura; Håkansson Kerstin; Usiello Alessandro; Borgkvist Anders; Lindskog Maria; Greengard Paul; Fisone Gilberto
Opposite regulation by typical and atypical anti-psychotics of ERK1/2, CREB and Elk-1 phosphorylation in mouse dorsal striatum.
Journal of neurochemistry 2003;86(2):451-9.
2003: Sabo Shasta L; Ikin Annat F; Buxbaum Joseph D; Greengard Paul
The amyloid precursor protein and its regulatory protein, FE65, in growth cones and synapses in vitro and in vivo.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2003;23(13):5407-15.
2003: Bloom Ona; Evergren Emma; Tomilin Nikolay; Kjaerulff Ole; Löw Peter; Brodin Lennart; Pieribone Vincent A; Greengard Paul; Shupliakov Oleg
Colocalization of synapsin and actin during synaptic vesicle recycling.
The Journal of cell biology 2003;161(4):737-47.
2003: Picconi Barbara; Centonze Diego; Håkansson Kerstin; Bernardi Giorgio; Greengard Paul; Fisone Gilberto; Cenci M Angela; Calabresi Paolo
Loss of bidirectional striatal synaptic plasticity in L-DOPA-induced dyskinesia.
Nature neuroscience 2003;6(5):501-6.
2003: Chi Ping; Greengard Paul; Ryan Timothy A
Synaptic vesicle mobilization is regulated by distinct synapsin I phosphorylation pathways at different frequencies.
Neuron 2003;38(1):69-78.
2003: Lindgren Niklas; Usiello Alessandro; Goiny Michel; Haycock John; Erbs Eric; Greengard Paul; Hokfelt Tomas; Borrelli Emiliana; Fisone Gilberto
Distinct roles of dopamine D2L and D2S receptor isoforms in the regulation of protein phosphorylation at presynaptic and postsynaptic sites.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(7):4305-9.
2003: Kim Young-Mi; Watanabe Takuo; Allen Patrick B; Kim Young-Myoung; Lee Shin-Jeong; Greengard Paul; Nairn Angus C; Kwon Young-Guen
PNUTS, a protein phosphatase 1 (PP1) nuclear targeting subunit. Characterization of its PP1- and RNA-binding domains and regulation by phosphorylation.
The Journal of biological chemistry 2003;278(16):13819-28.
2003: Kruse Maria Sol; Adachi Shinsuke; Scott Lena; Holtbäck Ulla; Greengard Paul; Aperia Anita; Brismar Hjalmar
Recruitment of renal dopamine 1 receptors requires an intact microtubulin network.
Pflügers Archiv : European journal of physiology 2003;445(5):534-9.
2003: Nishi Akinori; Liu Feng; Matsuyama Seiichiro; Hamada Miho; Higashi Hideho; Nairn Angus C; Greengard Paul
Metabotropic mGlu5 receptors regulate adenosine A2A receptor signaling.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(3):1322-7.
2003: Dou Fei; Netzer William J; Tanemura Kentaro; Li Feng; Hartl F Ulrich; Takashima Akihiko; Gouras Gunnar K; Greengard Paul; Xu Huaxi
Chaperones increase association of tau protein with microtubules.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(2):721-6.
2003: Endo Shogo; Nairn Angus C; Greengard Paul; Ito Masao
Thr123 of rat G-substrate contributes to its action as a protein phosphatase inhibitor.
Neuroscience research 2003;45(1):79-89.
2003: Cai Dongming; Leem Jae Yoon; Greenfield Jeffrey P; Wang Pei; Kim Benny S; Wang Runsheng; Lopes Kryslaine O; Kim Seong-Hun; Zheng Hui; Greengard Paul; Sisodia Sangram S; Thinakaran Gopal; Xu Huaxi
Presenilin-1 regulates intracellular trafficking and cell surface delivery of beta-amyloid precursor protein.
The Journal of biological chemistry 2003;278(5):3446-54.
2003: Hsieh-Wilson Linda C; Benfenati Fabio; Snyder Gretchen L; Allen Patrick B; Nairn Angus C; Greengard Paul
Phosphorylation of spinophilin modulates its interaction with actin filaments.
The Journal of biological chemistry 2003;278(2):1186-94.
2003: Watanabe Takuo; da Cruz e Silva Edgar F; Huang Hsien-Bin; Starkova Natalia; Kwon Young-Guen; Horiuchi Atsuko; Greengard Paul; Nairn Angus C
Preparation and characterization of recombinant protein phosphatase 1.
Methods in enzymology 2003;366():321-38.
2003: Norrholm S D; Bibb J A; Nestler E J; Ouimet C C; Taylor J R; Greengard P
Cocaine-induced proliferation of dendritic spines in nucleus accumbens is dependent on the activity of cyclin-dependent kinase-5.
Neuroscience 2003;116(1):19-22.
2002: Flores-Hernández Jorge; Cepeda Carlos; Hernández-Echeagaray Elizabeth; Calvert Christopher R; Jokel Eve S; Fienberg Allen A; Greengard Paul; Levine Michael S
Dopamine enhancement of NMDA currents in dissociated medium-sized striatal neurons: role of D1 receptors and DARPP-32.
Journal of neurophysiology 2002;88(6):3010-20.
2002: Pieribone Vincent A; Porton Barbara; Rendon Beatrice; Feng Jian; Greengard Paul; Kao Hung-Teh
Expression of synapsin III in nerve terminals and neurogenic regions of the adult brain.
The Journal of comparative neurology 2002;454(2):105-14.
2002: Takahashi Reisuke H; Milner Teresa A; Li Feng; Nam Ellen E; Edgar Mark A; Yamaguchi Haruyasu; Beal M Flint; Xu Huaxi; Greengard Paul; Gouras Gunnar K
Intraneuronal Alzheimer abeta42 accumulates in multivesicular bodies and is associated with synaptic pathology.
The American journal of pathology 2002;161(5):1869-79.
2002: Liu Feng; Virshup David M; Nairn Angus C; Greengard Paul
Mechanism of regulation of casein kinase I activity by group I metabotropic glutamate receptors.
The Journal of biological chemistry 2002;277(47):45393-9.
2002: Shupliakov Oleg; Bloom Ona; Gustafsson Jenny S; Kjaerulff Ole; Low Peter; Tomilin Nikolay; Pieribone Vincent A; Greengard Paul; Brodin Lennart
Impaired recycling of synaptic vesicles after acute perturbation of the presynaptic actin cytoskeleton.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(22):14476-81.
2002: Knockaert Marie; Greengard Paul; Meijer Laurent
Pharmacological inhibitors of cyclin-dependent kinases.
Trends in pharmacological sciences 2002;23(9):417-25.
2002: Irwin Nina; Chao Steven; Goritchenko Luda; Horiuchi Atsuko; Greengard Paul; Nairn Angus C; Benowitz Larry I
Nerve growth factor controls GAP-43 mRNA stability via the phosphoprotein ARPP-19.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(19):12427-31.
2002: Lindskog Maria; Svenningsson Per; Pozzi Laura; Kim Yong; Fienberg Allen A; Bibb James A; Fredholm Bertil B; Nairn Angus C; Greengard Paul; Fisone Gilberto
Involvement of DARPP-32 phosphorylation in the stimulant action of caffeine.
Nature 2002;418(6899):774-8.
2002: Menegon Andrea; Verderio Claudia; Leoni Chiara; Benfenati Fabio; Czernik Andrew J; Greengard Paul; Matteoli Michela; Valtorta Flavia
Spatial and temporal regulation of Ca2+/calmodulin-dependent protein kinase II activity in developing neurons.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2002;22(16):7016-26.
2002: Albert Katherine A; Hemmings Hugh C; Adamo Anna I B; Potkin Steven G; Akbarian Schahram; Sandman Curt A; Cotman Carl W; Bunney William E; Greengard Paul
Evidence for decreased DARPP-32 in the prefrontal cortex of patients with schizophrenia.
Archives of general psychiatry 2002;59(8):705-12.
2002: Alves Stephen E; Hoskin Elena; Lee Susan J; Brake Wayne G; Ferguson Deveroux; Luine Victoria; Allen Patrick B; Greengard Paul; McEwen Bruce S
Serotonin mediates CA1 spine density but is not crucial for ovarian steroid regulation of synaptic plasticity in the adult rat dorsal hippocampus.
Synapse (New York, N.Y.) 2002;45(2):143-51.
2002: Gasparini Laura; Netzer William J; Greengard Paul; Xu Huaxi
Does insulin dysfunction play a role in Alzheimer's disease?
Trends in pharmacological sciences 2002;23(6):288-93.
2002: Reed Tracy M; Repaske David R; Snyder Gretchen L; Greengard Paul; Vorhees Charles V
Phosphodiesterase 1B knock-out mice exhibit exaggerated locomotor hyperactivity and DARPP-32 phosphorylation in response to dopamine agonists and display impaired spatial learning.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2002;22(12):5188-97.
2002: Feng Jian; Chi Ping; Blanpied Thomas A; Xu Yimei; Magarinos Ana Maria; Ferreira Adriana; Takahashi Reisuke H; Kao Hung-Teh; McEwen Bruce S; Ryan Timothy A; Augustine George J; Greengard Paul
Regulation of neurotransmitter release by synapsin III.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2002;22(11):4372-80.
2002: Carr Andrew N; Schmidt Albrecht G; Suzuki Yoichi; del Monte Federica; Sato Yoji; Lanner Carita; Breeden Kristine; Jing Shao-Ling; Allen Patrick B; Greengard Paul; Yatani Atsuko; Hoit Brian D; Grupp Ingrid L; Hajjar Roger J; DePaoli-Roach Anna A; Kranias Evangelia G
Type 1 phosphatase, a negative regulator of cardiac function.
Molecular and cellular biology 2002;22(12):4124-35.
2002: Nishi Akinori; Bibb James A; Matsuyama Seiichiro; Hamada Miho; Higashi Hideho; Nairn Angus C; Greengard Paul
Regulation of DARPP-32 dephosphorylation at PKA- and Cdk5-sites by NMDA and AMPA receptors: distinct roles of calcineurin and protein phosphatase-2A.
Journal of neurochemistry 2002;81(4):832-41.
2002: Yan Zhen; Chi Ping; Bibb James A; Ryan Timothy A; Greengard Paul
Roscovitine: a novel regulator of P/Q-type calcium channels and transmitter release in central neurons.
The Journal of physiology 2002;540(Pt 3):761-70.
2002: Kao Hung-Teh; Song Hong-jun; Porton Barbara; Ming Guo-li; Hoh Josephine; Abraham Michael; Czernik Andrew J; Pieribone Vincent A; Poo Mu-ming; Greengard Paul
A protein kinase A-dependent molecular switch in synapsins regulates neurite outgrowth.
Nature neuroscience 2002;5(5):431-7.
2002: Matsuyama Seiichiro; Higashi Hideho; Maeda Hisao; Greengard Paul; Nishi Akinori
Neurotensin regulates DARPP-32 thr34 phosphorylation in neostriatal neurons by activation of dopamine D1-type receptors.
Journal of neurochemistry 2002;81(2):325-34.
2002: Zachariou Venetia; Benoit-Marand Marianne; Allen Patrick B; Ingrassia Peter; Fienberg Allen A; Gonon Francois; Greengard Paul; Picciotto Marina R
Reduction of cocaine place preference in mice lacking the protein phosphatase 1 inhibitors DARPP 32 or Inhibitor 1.
Biological psychiatry 2002;51(8):612-20.
2002: Greenfield Jeffrey P; Leung Lawrence W; Cai Dongming; Kaasik Krista; Gross Rachel S; Rodriguez-Boulan Enrique; Greengard Paul; Xu Huaxi
Estrogen lowers Alzheimer beta-amyloid generation by stimulating trans-Golgi network vesicle biogenesis.
The Journal of biological chemistry 2002;277(14):12128-36.
2002: Yamagata Yoko; Jovanovic Jasmina N; Czernik Andrew J; Greengard Paul; Obata Kunihiko
Bidirectional changes in synapsin I phosphorylation at MAP kinase-dependent sites by acute neuronal excitation in vivo.
Journal of neurochemistry 2002;80(5):835-42.
2002: Svenningsson Per; Tzavara Eleni T; Liu Feng; Fienberg Allen A; Nomikos George G; Greengard Paul
DARPP-32 mediates serotonergic neurotransmission in the forebrain.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(5):3188-93.
2002: Svenningsson Per; Tzavara Eleni T; Witkin Jeffrey M; Fienberg Allen A; Nomikos George G; Greengard Paul
Involvement of striatal and extrastriatal DARPP-32 in biochemical and behavioral effects of fluoxetine (Prozac).
Proceedings of the National Academy of Sciences of the United States of America 2002;99(5):3182-7.
2002: Scott Lena; Kruse Maria Sol; Forssberg Hans; Brismar Hjalmar; Greengard Paul; Aperia Anita
Selective up-regulation of dopamine D1 receptors in dendritic spines by NMDA receptor activation.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(3):1661-4.
2002: Grossman Stacie D; Hsieh-Wilson Linda C; Allen Patrick B; Nairn Angus C; Greengard Paul
The actin-binding domain of spinophilin is necessary and sufficient for targeting to dendritic spines.
Neuromolecular medicine 2002;2(1):61-9.
2001: Chi P; Greengard P; Ryan T A
Synapsin dispersion and reclustering during synaptic activity.
Nature neuroscience 2001;4(12):1187-93.
2001: Muly E C; Greengard P; Goldman-Rakic P S
Distribution of protein phosphatases-1 alpha and -1 gamma 1 and the D(1) dopamine receptor in primate prefrontal cortex: Evidence for discrete populations of spines.
The Journal of comparative neurology 2001;440(3):261-70.
2001: Greengard P
The neurobiology of slow synaptic transmission.
Science (New York, N.Y.) 2001;294(5544):1024-30.
2001: Nairn A C; Greengard P
A novel cyclin provides a link between dopamine and RNA processing.
Neuron 2001;32(2):174-6.
2001: Jovanovic J N; Sihra T S; Nairn A C; Hemmings H C; Greengard P; Czernik A J
Opposing changes in phosphorylation of specific sites in synapsin I during Ca2+-dependent glutamate release in isolated nerve terminals.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2001;21(20):7944-53.
2001: Stafstrom-Davis C A; Ouimet C C; Feng J; Allen P B; Greengard P; Houpt T A
Impaired conditioned taste aversion learning in spinophilin knockout mice.
Learning & memory (Cold Spring Harbor, N.Y.) 2001;8(5):272-8.
2001: Liu F; Ma X H; Ule J; Bibb J A; Nishi A; DeMaggio A J; Yan Z; Nairn A C; Greengard P
Regulation of cyclin-dependent kinase 5 and casein kinase 1 by metabotropic glutamate receptors.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(20):11062-8.
2001: Yan R; Han P; Miao H; Greengard P; Xu H
The transmembrane domain of the Alzheimer's beta-secretase (BACE1) determines its late Golgi localization and access to beta -amyloid precursor protein (APP) substrate.
The Journal of biological chemistry 2001;276(39):36788-96.
2001: Eklöf A C; Holtbäck U; Svennilson J; Fienberg A; Greengard P; Aperia A
Increased blood pressure and loss of anp-induced natriuresis in mice lacking DARPP-32 gene.
Clinical and experimental hypertension (New York, N.Y. : 1993) 2001;23(6):449-60.
2001: Carr A N; Sutliff R L; Weber C S; Allen P B; Greengard P; de Lanerolle P; Kranias E G; Paul R J
Is myosin phosphatase regulated in vivo by inhibitor-1? Evidence from inhibitor-1 knockout mice.
The Journal of physiology 2001;534(Pt. 2):357-66.
2001: Calabresi P; Gubellini P; Picconi B; Centonze D; Pisani A; Bonsi P; Greengard P; Hipskind R A; Borrelli E; Bernardi G
Inhibition of mitochondrial complex II induces a long-term potentiation of NMDA-mediated synaptic excitation in the striatum requiring endogenous dopamine.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2001;21(14):5110-20.
2001: Greengard P
The neurobiology of dopamine signaling.
Bioscience reports 2001;21(3):247-69.
2001: Sabo S L; Ikin A F; Buxbaum J D; Greengard P
The Alzheimer amyloid precursor protein (APP) and FE65, an APP-binding protein, regulate cell movement.
The Journal of cell biology 2001;153(7):1403-14.
2001: Humeau Y; Doussau F; Vitiello F; Greengard P; Benfenati F; Poulain B
Synapsin controls both reserve and releasable synaptic vesicle pools during neuronal activity and short-term plasticity in Aplysia.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2001;21(12):4195-206.
2001: Huang H B; Chen Y C; Horiuchi A; Tsai L H; Liu H T; Chyan C L; Hsieh M J; Liu C K; Lin F M; Greengard P; Nairn A C; Shiao M S; Lin T H
Backbone 1H, 15N, and 13C resonance assignments of ARPP-19.
Journal of biomolecular NMR 2001;19(4):383-4.
2001: Gasparini L; Gouras G K; Wang R; Gross R S; Beal M F; Greengard P; Xu H
Stimulation of beta-amyloid precursor protein trafficking by insulin reduces intraneuronal beta-amyloid and requires mitogen-activated protein kinase signaling.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2001;21(8):2561-70.
2001: Dulubova I; Horiuchi A; Snyder G L; Girault J A; Czernik A J; Shao L; Ramabhadran R; Greengard P; Nairn A C
ARPP-16/ARPP-19: a highly conserved family of cAMP-regulated phosphoproteins.
Journal of neurochemistry 2001;77(1):229-38.
2001: Bibb J A; Nishi A; O'Callaghan J P; Ule J; Lan M; Snyder G L; Horiuchi A; Saito T; Hisanaga S; Czernik A J; Nairn A C; Greengard P
Phosphorylation of protein phosphatase inhibitor-1 by Cdk5.
The Journal of biological chemistry 2001;276(17):14490-7.
2001: Bibb J A; Chen J; Taylor J R; Svenningsson P; Nishi A; Snyder G L; Yan Z; Sagawa Z K; Ouimet C C; Nairn A C; Nestler E J; Greengard P
Effects of chronic exposure to cocaine are regulated by the neuronal protein Cdk5.
Nature 2001;410(6826):376-80.
2001: Watanabe T; Huang H B; Horiuchi A; da Cruze Silva E F; Hsieh-Wilson L; Allen P B; Shenolikar S; Greengard P; Nairn A C
Protein phosphatase 1 regulation by inhibitors and targeting subunits.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(6):3080-5.
2001: Brake W G; Alves S E; Dunlop J C; Lee S J; Bulloch K; Allen P B; Greengard P; McEwen B S
Novel target sites for estrogen action in the dorsal hippocampus: an examination of synaptic proteins.
Endocrinology 2001;142(3):1284-9.
2001: Arrow K J; Axelrod J; Benacerraf B; Berg P; Bishop J M; Bloembergen N; Brown H C; Cibelli J; Cohen S; Cooper L N; Corey E J; Cronin J W; Curl R; Dulbecco R; Fischer E H; Fitch V L; Fogel R; Friedman J I; Furchgott R F; Gell-Mann M; Gilbert W; Gilman A; Glaser D; Glashow S L; Green R M; Greengard P; Guillemin R; Hayflick L; Hauptman H A; Heckman J J; Heeger A; Herschbach D; Hubel D H; Hulse R; Kandel E; Karle J; Klein L R; Kohn W; Kornberg A; Krebs E G; Lanza R P; Laughlin R; Lederman L; Lee D M; Lewis E; Lipscomb W; Marcus R A; McFadden D; Merrifield R B; Merton R; Modigliani F; Molina M J; Murad F; Nirenberg M W; North D C; Olah G A; Osheroff D; Palade G E; Perl M; Ramsey N F; Richter B; Roberts R J; Samuelson P A; Schwartz M; Sharp P A; Smalley R E; Smith H O; Solow R M; Stormer H; Taube H; Taylor R; Thomas E D; Tobin J; Tonegawa S; Townes C; Watson J D; Weinberg S; Weller T H; West M D; Wieschaus E F; Wiesel T N; Wilson R W
Nobel laureates' letter to President Bush.
Washington post (Washington, D.C. : 1974) 2001;():A02.
2001: Hilfiker S; Czernik A J; Greengard P; Augustine G J
Tonically active protein kinase A regulates neurotransmitter release at the squid giant synapse.
The Journal of physiology 2001;531(Pt 1):141-6.
2001: Cheetham J J; Hilfiker S; Benfenati F; Weber T; Greengard P; Czernik A J
Identification of synapsin I peptides that insert into lipid membranes.
The Biochemical journal 2001;354(Pt 1):57-66.
2001: Lidow M S; Song Z M; Castner S A; Allen P B; Greengard P; Goldman-Rakic P S
Antipsychotic treatment induces alterations in dendrite- and spine-associated proteins in dopamine-rich areas of the primate cerebral cortex.
Biological psychiatry 2001;49(1):1-12.
2001: Risinger F O; Freeman P A; Greengard P; Fienberg A A
Motivational effects of ethanol in DARPP-32 knock-out mice.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2001;21(1):340-8.
2001: Leclerc S; Garnier M; Hoessel R; Marko D; Bibb J A; Snyder G L; Greengard P; Biernat J; Wu Y Z; Mandelkow E M; Eisenbrand G; Meijer L
Indirubins inhibit glycogen synthase kinase-3 beta and CDK5/p25, two protein kinases involved in abnormal tau phosphorylation in Alzheimer's disease. A property common to most cyclin-dependent kinase inhibitors?
The Journal of biological chemistry 2001;276(1):251-60.
2000: Calabresi P; Gubellini P; Centonze D; Picconi B; Bernardi G; Chergui K; Svenningsson P; Fienberg A A; Greengard P
Dopamine and cAMP-regulated phosphoprotein 32 kDa controls both striatal long-term depression and long-term potentiation, opposing forms of synaptic plasticity.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2000;20(22):8443-51.
2000: Nishi A; Bibb J A; Snyder G L; Higashi H; Nairn A C; Greengard P
Amplification of dopaminergic signaling by a positive feedback loop.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(23):12840-5.
2000: Menegon A; Dunlap D D; Castano F; Benfenati F; Czernik A J; Greengard P; Valtorta F
Use of phosphosynapsin I-specific antibodies for image analysis of signal transduction in single nerve terminals.
Journal of cell science 2000;113 ( Pt 20)():3573-82.
2000: Leost M; Schultz C; Link A; Wu Y Z; Biernat J; Mandelkow E M; Bibb J A; Snyder G L; Greengard P; Zaharevitz D W; Gussio R; Senderowicz A M; Sausville E A; Kunick C; Meijer L
Paullones are potent inhibitors of glycogen synthase kinase-3beta and cyclin-dependent kinase 5/p25.
European journal of biochemistry / FEBS 2000;267(19):5983-94.
2000: Iijima K; Ando K; Takeda S; Satoh Y; Seki T; Itohara S; Greengard P; Kirino Y; Nairn A C; Suzuki T
Neuron-specific phosphorylation of Alzheimer's beta-amyloid precursor protein by cyclin-dependent kinase 5.
Journal of neurochemistry 2000;75(3):1085-91.
2000: Onofri F; Giovedi S; Kao H T; Valtorta F; Bongiorno Borbone L; De Camilli P; Greengard P; Benfenati F
Specificity of the binding of synapsin I to Src homology 3 domains.
The Journal of biological chemistry 2000;275(38):29857-67.
2000: Huang H B; Chen Y C; Tsai L H; Wang H; Lin F M; Horiuchi A; Greengard P; Nairn A C; Shiao M S; Lin T H
Backbone 1H, 15N, and 13C resonance assignments of inhibitor-2 -- a protein inhibitor of protein phosphatase-1.
Journal of biomolecular NMR 2000;17(4):359-60.
2000: Feng J; Yan Z; Ferreira A; Tomizawa K; Liauw J A; Zhuo M; Allen P B; Ouimet C C; Greengard P
Spinophilin regulates the formation and function of dendritic spines.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(16):9287-92.
2000: Caporaso G L; Bibb J A; Snyder G L; Valle C; Rakhilin S; Fienberg A A; Hemmings H C; Nairn A C; Greengard P
Drugs of abuse modulate the phosphorylation of ARPP-21, a cyclic AMP-regulated phosphoprotein enriched in the basal ganglia.
Neuropharmacology 2000;39(9):1637-44.
2000: Svenningsson P; Fienberg A A; Allen P B; Moine C L; Lindskog M; Fisone G; Greengard P; Fredholm B B
Dopamine D(1) receptor-induced gene transcription is modulated by DARPP-32.
Journal of neurochemistry 2000;75(1):248-57.
2000: Snyder G L; Allen P B; Fienberg A A; Valle C G; Huganir R L; Nairn A C; Greengard P
Regulation of phosphorylation of the GluR1 AMPA receptor in the neostriatum by dopamine and psychostimulants in vivo.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2000;20(12):4480-8.
2000: Heyser C J; Fienberg A A; Greengard P; Gold L H
DARPP-32 knockout mice exhibit impaired reversal learning in a discriminated operant task.
Brain research 2000;867(1-2):122-30.
2000: Bibb J A; Yan Z; Svenningsson P; Snyder G L; Pieribone V A; Horiuchi A; Nairn A C; Messer A; Greengard P
Severe deficiencies in dopamine signaling in presymptomatic Huntington's disease mice.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(12):6809-14.
2000: Flores-Hernandez J; Hernandez S; Snyder G L; Yan Z; Fienberg A A; Moss S J; Greengard P; Surmeier D J
D(1) dopamine receptor activation reduces GABA(A) receptor currents in neostriatal neurons through a PKA/DARPP-32/PP1 signaling cascade.
Journal of neurophysiology 2000;83(5):2996-3004.
2000: Ferreira A; Kao H T; Feng J; Rapoport M; Greengard P
Synapsin III: developmental expression, subcellular localization, and role in axon formation.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2000;20(10):3736-44.
2000: Allen P B; Hvalby O; Jensen V; Errington M L; Ramsay M; Chaudhry F A; Bliss T V; Storm-Mathisen J; Morris R G; Andersen P; Greengard P
Protein phosphatase-1 regulation in the induction of long-term potentiation: heterogeneous molecular mechanisms.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2000;20(10):3537-43.
2000: Walaas S I; Hilfiker S; Li L; Chin L S; Greengard P
Decrease in phorbol ester-induced potentiation of noradrenaline release in synapsin I-deficient mice.
Synapse (New York, N.Y.) 2000;36(2):114-9.
2000: Jovanovic J N; Czernik A J; Fienberg A A; Greengard P; Sihra T S
Synapsins as mediators of BDNF-enhanced neurotransmitter release.
Nature neuroscience 2000;3(4):323-9.
2000: Näslund J; Haroutunian V; Mohs R; Davis K L; Davies P; Greengard P; Buxbaum J D
Correlation between elevated levels of amyloid beta-peptide in the brain and cognitive decline.
JAMA : the journal of the American Medical Association 2000;283(12):1571-7.
2000: Fienberg A A; Greengard P
The DARPP-32 knockout mouse.
Brain research. Brain research reviews 2000;31(2-3):313-9.
2000: Aizman O; Brismar H; Uhlén P; Zettergren E; Levey A I; Forssberg H; Greengard P; Aperia A
Anatomical and physiological evidence for D1 and D2 dopamine receptor colocalization in neostriatal neurons.
Nature neuroscience 2000;3(3):226-30.
2000: Svenningsson P; Lindskog M; Ledent C; Parmentier M; Greengard P; Fredholm B B; Fisone G
Regulation of the phosphorylation of the dopamine- and cAMP-regulated phosphoprotein of 32 kDa in vivo by dopamine D1, dopamine D2, and adenosine A2A receptors.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(4):1856-60.
2000: Mani S K; Fienberg A A; O'Callaghan J P; Snyder G L; Allen P B; Dash P K; Moore A N; Mitchell A J; Bibb J; Greengard P; O'Malley B W
Requirement for DARPP-32 in progesterone-facilitated sexual receptivity in female rats and mice.
Science (New York, N.Y.) 2000;287(5455):1053-6.
2000: Gouras G K; Xu H; Gross R S; Greenfield J P; Hai B; Wang R; Greengard P
Testosterone reduces neuronal secretion of Alzheimer's beta-amyloid peptides.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(3):1202-5.
2000: Gouras G K; Tsai J; Naslund J; Vincent B; Edgar M; Checler F; Greenfield J P; Haroutunian V; Buxbaum J D; Xu H; Greengard P; Relkin N R
Intraneuronal Abeta42 accumulation in human brain.
The American journal of pathology 2000;156(1):15-20.
1999: Bibb J A; Snyder G L; Nishi A; Yan Z; Meijer L; Fienberg A A; Tsai L H; Kwon Y T; Girault J A; Czernik A J; Huganir R L; Hemmings H C; Nairn A C; Greengard P
Phosphorylation of DARPP-32 by Cdk5 modulates dopamine signalling in neurons.
Nature 1999;402(6762):669-71.
1999: Porton B; Kao H T; Greengard P
Characterization of transcripts from the synapsin III gene locus.
Journal of neurochemistry 1999;73(6):2266-71.
1999: Kao H T; Porton B; Hilfiker S; Stefani G; Pieribone V A; DeSalle R; Greengard P
Molecular evolution of the synapsin gene family.
The Journal of experimental zoology 1999;285(4):360-77.
1999: Heierhorst J; Mitchelhill K I; Mann R J; Tiganis T; Czernik A J; Greengard P; Kemp B E
Synapsins as major neuronal Ca2+/S100A1-interacting proteins.
The Biochemical journal 1999;344 Pt 2():577-83.
1999: Greenfield J P; Xu H; Greengard P; Gandy S; Seeger M
Generation of the amyloid-beta peptide N terminus in Saccharomyces cerevisiae expressing human Alzheimer's amyloid-beta precursor protein.
The Journal of biological chemistry 1999;274(48):33843-6.
1999: Nishi A; Fisone G; Snyder G L; Dulubova I; Aperia A; Nairn A C; Greengard P
Regulation of Na+, K+-ATPase isoforms in rat neostriatum by dopamine and protein kinase C.
Journal of neurochemistry 1999;73(4):1492-501.
1999: Zhou Y; Schlussman S D; Ho A; Spangler R; Fienberg A A; Greengard P; Kreek M J
Effects of chronic 'Binge' cocaine administration on plasma ACTH and corticosterone levels in mice deficient in DARPP-32.
Neuroendocrinology 1999;70(3):196-9.
1999: McAvoy T; Allen P B; Obaishi H; Nakanishi H; Takai Y; Greengard P; Nairn A C; Hemmings H C
Regulation of neurabin I interaction with protein phosphatase 1 by phosphorylation.
Biochemistry 1999;38(39):12943-9.
1999: Yan Z; Feng J; Fienberg A A; Greengard P
D(2) dopamine receptors induce mitogen-activated protein kinase and cAMP response element-binding protein phosphorylation in neurons.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(20):11607-12.
1999: Hilfiker S; Pieribone V A; Nordstedt C; Greengard P; Czernik A J
Regulation of synaptotagmin I phosphorylation by multiple protein kinases.
Journal of neurochemistry 1999;73(3):921-32.
1999: Allen P B; Hsieh-Wilson L; Yan Z; Feng J; Ouimet C C; Greengard P
Control of protein phosphatase I in the dendrite.
Biochemical Society transactions 1999;27(4):543-6.
1999: Greengard P; Allen P B; Nairn A C
Beyond the dopamine receptor: the DARPP-32/protein phosphatase-1 cascade.
Neuron 1999;23(3):435-47.
1999: Scrimgeour A G; Allen P B; Fienberg A A; Greengard P; Lawrence J C
Inhibitor-1 is not required for the activation of glycogen synthase by insulin in skeletal muscle.
The Journal of biological chemistry 1999;274(30):20949-52.
1999: Nishi A; Snyder G L; Fienberg A A; Fisone G; Aperia A; Nairn A C; Greengard P
Requirement for DARPP-32 in mediating effect of dopamine D2 receptor activation.
The European journal of neuroscience 1999;11(7):2589-92.
1999: Cheng S X; Aizman O; Nairn A C; Greengard P; Aperia A
[Ca2+]i determines the effects of protein kinases A and C on activity of rat renal Na+,K+-ATPase.
The Journal of physiology 1999;518 ( Pt 1)():37-46.
1999: Holtbäck U; Brismar H; DiBona G F; Fu M; Greengard P; Aperia A
Receptor recruitment: a mechanism for interactions between G protein-coupled receptors.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(13):7271-5.
1999: Ando K; Oishi M; Takeda S; Iijima K; Isohara T; Nairn A C; Kirino Y; Greengard P; Suzuki T
Role of phosphorylation of Alzheimer's amyloid precursor protein during neuronal differentiation.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1999;19(11):4421-7.
1999: Lindskog M; Svenningsson P; Fredholm B; Greengard P; Fisone G
Mu- and delta-opioid receptor agonists inhibit DARPP-32 phosphorylation in distinct populations of striatal projection neurons.
The European journal of neuroscience 1999;11(6):2182-6.
1999: Isohara T; Horiuchi A; Watanabe T; Ando K; Czernik A J; Uno I; Greengard P; Nairn A C; Suzuki T
Phosphorylation of the cytoplasmic domain of Alzheimer's beta-amyloid precursor protein at Ser655 by a novel protein kinase.
Biochemical and biophysical research communications 1999;258(2):300-5.
1999: Nishi A; Snyder G L; Nairn A C; Greengard P
Role of calcineurin and protein phosphatase-2A in the regulation of DARPP-32 dephosphorylation in neostriatal neurons.
Journal of neurochemistry 1999;72(5):2015-21.
1999: Fienberg A A; Nordstedt C; Belting H G; Czernik A J; Nairn A C; Gandy S; Greengard P; Ruddle F H
Phylogenetically conserved CK-II phosphorylation site of the murine homeodomain protein Hoxb-6.
The Journal of experimental zoology 1999;285(1):76-84.
1999: Hsieh-Wilson L C; Allen P B; Watanabe T; Nairn A C; Greengard P
Characterization of the neuronal targeting protein spinophilin and its interactions with protein phosphatase-1.
Biochemistry 1999;38(14):4365-73.
1999: Hiroi N; Fienberg A A; Haile C N; Alburges M; Hanson G R; Greengard P; Nestler E J
Neuronal and behavioural abnormalities in striatal function in DARPP-32-mutant mice.
The European journal of neuroscience 1999;11(3):1114-8.
1999: Sabo S L; Lanier L M; Ikin A F; Khorkova O; Sahasrabudhe S; Greengard P; Buxbaum J D
Regulation of beta-amyloid secretion by FE65, an amyloid protein precursor-binding protein.
The Journal of biological chemistry 1999;274(12):7952-7.
1999: Huang H B; Horiuchi A; Watanabe T; Shih S R; Tsay H J; Li H C; Greengard P; Nairn A C
Characterization of the inhibition of protein phosphatase-1 by DARPP-32 and inhibitor-2.
The Journal of biological chemistry 1999;274(12):7870-8.
1999: Endo S; Suzuki M; Sumi M; Nairn A C; Morita R; Yamakawa K; Greengard P; Ito M
Molecular identification of human G-substrate, a possible downstream component of the cGMP-dependent protein kinase cascade in cerebellar Purkinje cells.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(5):2467-72.
1999: Hilfiker S; Pieribone V A; Czernik A J; Kao H T; Augustine G J; Greengard P
Synapsins as regulators of neurotransmitter release.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 1999;354(1381):269-79.
1999: Hilfiker S; Greengard P; Augustine G J
Coupling calcium to SNARE-mediated synaptic vesicle fusion.
Nature neuroscience 1999;2(2):104-6.
1999: Watanabe T; Sukegawa J; Sukegawa I; Tomita S; Iijima K; Oguchi S; Suzuki T; Nairn A C; Greengard P
A 127-kDa protein (UV-DDB) binds to the cytoplasmic domain of the Alzheimer's amyloid precursor protein.
Journal of neurochemistry 1999;72(2):549-56.
1999: Yan Z; Hsieh-Wilson L; Feng J; Tomizawa K; Allen P B; Fienberg A A; Nairn A C; Greengard P
Protein phosphatase 1 modulation of neostriatal AMPA channels: regulation by DARPP-32 and spinophilin.
Nature neuroscience 1999;2(1):13-7.
1999: Mayerhofer A; Hemmings H C; Snyder G L; Greengard P; Boddien S; Berg U; Brucker C
Functional dopamine-1 receptors and DARPP-32 are expressed in human ovary and granulosa luteal cells in vitro.
The Journal of clinical endocrinology and metabolism 1999;84(1):257-64.
1999: Greenfield J P; Tsai J; Gouras G K; Hai B; Thinakaran G; Checler F; Sisodia S S; Greengard P; Xu H
Endoplasmic reticulum and trans-Golgi network generate distinct populations of Alzheimer beta-amyloid peptides.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(2):742-7.
1999: Porton B; Kao H T; Greengard P
Cloning of cDNAs encoding human synapsins IIa and IIb.
DNA sequence : the journal of DNA sequencing and mapping 1999;10(1):49-54.
1999: Lindskog M; Svenningsson P; Fredholm B B; Greengard P; Fisone G
Activation of dopamine D2 receptors decreases DARPP-32 phosphorylation in striatonigral and striatopallidal projection neurons via different mechanisms.
Neuroscience 1999;88(4):1005-8.
1998: Snyder G L; Fienberg A A; Huganir R L; Greengard P
A dopamine/D1 receptor/protein kinase A/dopamine- and cAMP-regulated phosphoprotein (Mr 32 kDa)/protein phosphatase-1 pathway regulates dephosphorylation of the NMDA receptor.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1998;18(24):10297-303.
1998: Meredith J M; Moffatt C A; Auger A P; Snyder G L; Greengard P; Blaustein J D
Mating-related stimulation induces phosphorylation of dopamine- and cyclic AMP-regulated phosphoprotein-32 in progestin receptor-containing areas in the female rat brain.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1998;18(23):10189-95.
1998: Gouras G K; Xu H; Jovanovic J N; Buxbaum J D; Wang R; Greengard P; Relkin N R; Gandy S
Generation and regulation of beta-amyloid peptide variants by neurons.
Journal of neurochemistry 1998;71(5):1920-5.
1998: Ouimet C C; Langley-Gullion K C; Greengard P
Quantitative immunocytochemistry of DARPP-32-expressing neurons in the rat caudatoputamen.
Brain research 1998;808(1):8-12.
1998: Fienberg A A; Hiroi N; Mermelstein P G; Song W; Snyder G L; Nishi A; Cheramy A; O'Callaghan J P; Miller D B; Cole D G; Corbett R; Haile C N; Cooper D C; Onn S P; Grace A A; Ouimet C C; White F J; Hyman S E; Surmeier D J; Girault J; Nestler E J; Greengard P
DARPP-32: regulator of the efficacy of dopaminergic neurotransmission.
Science (New York, N.Y.) 1998;281(5378):838-42.
1998: Hilfiker S; Schweizer F E; Kao H T; Czernik A J; Greengard P; Augustine G J
Two sites of action for synapsin domain E in regulating neurotransmitter release.
Nature neuroscience 1998;1(1):29-35.
1998: Greengard P; Nairn A C; Girault J A; Ouimet C C; Snyder G L; Fisone G; Allen P B; Fienberg A; Nishi A
The DARPP-32/protein phosphatase-1 cascade: a model for signal integration.
Brain research. Brain research reviews 1998;26(2-3):274-84.
1998: Brismar H; Asghar M; Carey R M; Greengard P; Aperia A
Dopamine-induced recruitment of dopamine D1 receptors to the plasma membrane.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(10):5573-8.
1998: Svenningsson P; Lindskog M; Rognoni F; Fredholm B B; Greengard P; Fisone G
Activation of adenosine A2A and dopamine D1 receptors stimulates cyclic AMP-dependent phosphorylation of DARPP-32 in distinct populations of striatal projection neurons.
Neuroscience 1998;84(1):223-8.
1998: Schiffmann S N; Desdouits F; Menu R; Greengard P; Vincent J D; Vanderhaeghen J J; Girault J A
Modulation of the voltage-gated sodium current in rat striatal neurons by DARPP-32, an inhibitor of protein phosphatase.
The European journal of neuroscience 1998;10(4):1312-20.
1998: Fisone G; Snyder G L; Aperia A; Greengard P
Na+,K(+)-ATPase phosphorylation in the choroid plexus: synergistic regulation by serotonin/protein kinase C and isoproterenol/cAMP-PK/PP-1 pathways.
Molecular medicine (Cambridge, Mass.) 1998;4(4):258-65.
1998: Xu H; Gouras G K; Greenfield J P; Vincent B; Naslund J; Mazzarelli L; Fried G; Jovanovic J N; Seeger M; Relkin N R; Liao F; Checler F; Buxbaum J D; Chait B T; Thinakaran G; Sisodia S S; Wang R; Greengard P; Gandy S
Estrogen reduces neuronal generation of Alzheimer beta-amyloid peptides.
Nature medicine 1998;4(4):447-51.
1998: Kao H T; Porton B; Czernik A J; Feng J; Yiu G; Häring M; Benfenati F; Greengard P
A third member of the synapsin gene family.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(8):4667-72.
1998: Allen P B; Kwon Y G; Nairn A C; Greengard P
Isolation and characterization of PNUTS, a putative protein phosphatase 1 nuclear targeting subunit.
The Journal of biological chemistry 1998;273(7):4089-95.
1998: Desdouits F; Siciliano J C; Nairn A C; Greengard P; Girault J A
Dephosphorylation of Ser-137 in DARPP-32 by protein phosphatases 2A and 2C: different roles in vitro and in striatonigral neurons.
The Biochemical journal 1998;330 ( Pt 1)():211-6.
1998: Desdouits-Magnen J; Desdouits F; Takeda S; Syu L J; Saltiel A R; Buxbaum J D; Czernik A J; Nairn A C; Greengard P
Regulation of secretion of Alzheimer amyloid precursor protein by the mitogen-activated protein kinase cascade.
Journal of neurochemistry 1998;70(2):524-30.
1998: Ferreira A; Chin L S; Li L; Lanier L M; Kosik K S; Greengard P
Distinct roles of synapsin I and synapsin II during neuronal development.
Molecular medicine (Cambridge, Mass.) 1998;4(1):22-8.
1998: Aperia A; Eklöf A C; Holtbäck U; Nowicki S; Sundelöf M; Greengard P
The renal dopamine system.
Advances in pharmacology (San Diego, Calif.) 1998;42():870-3.
1997: Nielander H B; Onofri F; Schaeffer E; Menegon A; Fesce R; Valtorta F; Greengard P; Benfenati F
Phosphorylation-dependent effects of synapsin IIa on actin polymerization and network formation.
The European journal of neuroscience 1997;9(12):2712-22.
1997: Vaccaro P; Dente L; Onofri F; Zucconi A; Martinelli S; Valtorta F; Greengard P; Cesareni G; Benfenati F
Anti-synapsin monoclonal antibodies: epitope mapping and inhibitory effects on phosphorylation and Grb2 binding.
Brain research. Molecular brain research 1997;52(1):1-16.
1997: Cheng X J; Höög J O; Nairn A C; Greengard P; Aperia A
Regulation of rat Na(+)-K(+)-ATPase activity by PKC is modulated by state of phosphorylation of Ser-943 by PKA.
The American journal of physiology 1997;273(6 Pt 1):C1981-6.
1997: Blank T; Nijholt I; Teichert U; Kügler H; Behrsing H; Fienberg A; Greengard P; Spiess J
The phosphoprotein DARPP-32 mediates cAMP-dependent potentiation of striatal N-methyl-D-aspartate responses.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(26):14859-64.
1997: Stefani G; Onofri F; Valtorta F; Vaccaro P; Greengard P; Benfenati F
Kinetic analysis of the phosphorylation-dependent interactions of synapsin I with rat brain synaptic vesicles.
The Journal of physiology 1997;504 ( Pt 3)():501-15.
1997: Schnabel R; Metzger M; Jiang S; Hemmings H C; Greengard P; Braun K
Localization of dopamine D1 receptors and dopaminoceptive neurons in the chick forebrain.
The Journal of comparative neurology 1997;388(1):146-68.
1997: Nishi A; Snyder G L; Greengard P
Bidirectional regulation of DARPP-32 phosphorylation by dopamine.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1997;17(21):8147-55.
1997: Onofri F; Giovedì S; Vaccaro P; Czernik A J; Valtorta F; De Camilli P; Greengard P; Benfenati F
Synapsin I interacts with c-Src and stimulates its tyrosine kinase activity.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(22):12168-73.
1997: Cheng X J; Fisone G; Aizman O; Aizman R; Levenson R; Greengard P; Aperia A
PKA-mediated phosphorylation and inhibition of Na(+)-K(+)-ATPase in response to beta-adrenergic hormone.
The American journal of physiology 1997;273(3 Pt 1):C893-901.
1997: Allen P B; Ouimet C C; Greengard P
Spinophilin, a novel protein phosphatase 1 binding protein localized to dendritic spines.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(18):9956-61.
1997: Belusa R; Wang Z M; Matsubara T; Sahlgren B; Dulubova I; Nairn A C; Ruoslahti E; Greengard P; Aperia A
Mutation of the protein kinase C phosphorylation site on rat alpha1 Na+,K+-ATPase alters regulation of intracellular Na+ and pH and influences cell shape and adhesiveness.
The Journal of biological chemistry 1997;272(32):20179-84.
1997: Langley K C; Bergson C; Greengard P; Ouimet C C
Co-localization of the D1 dopamine receptor in a subset of DARPP-32-containing neurons in rat caudate-putamen.
Neuroscience 1997;78(4):977-83.
1997: Seeger M; Nordstedt C; Petanceska S; Kovacs D M; Gouras G K; Hahne S; Fraser P; Levesque L; Czernik A J; George-Hyslop P S; Sisodia S S; Thinakaran G; Tanzi R E; Greengard P; Gandy S
Evidence for phosphorylation and oligomeric assembly of presenilin 1.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(10):5090-4.
1997: Suzuki T; Ando K; Isohara T; Oishi M; Lim G S; Satoh Y; Wasco W; Tanzi R E; Nairn A C; Greengard P; Gandy S E; Kirino Y
Phosphorylation of Alzheimer beta-amyloid precursor-like proteins.
Biochemistry 1997;36(15):4643-9.
1997: Xu H; Sweeney D; Wang R; Thinakaran G; Lo A C; Sisodia S S; Greengard P; Gandy S
Generation of Alzheimer beta-amyloid protein in the trans-Golgi network in the apparent absence of vesicle formation.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(8):3748-52.
1997: Kwon Y G; Huang H B; Desdouits F; Girault J A; Greengard P; Nairn A C
Characterization of the interaction between DARPP-32 and protein phosphatase 1 (PP-1): DARPP-32 peptides antagonize the interaction of PP-1 with binding proteins.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(8):3536-41.
1997: Huang H B; Horiuchi A; Goldberg J; Greengard P; Nairn A C
Site-directed mutagenesis of amino acid residues of protein phosphatase 1 involved in catalysis and inhibitor binding.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(8):3530-5.
1997: Kwon Y G; Lee S Y; Choi Y; Greengard P; Nairn A C
Cell cycle-dependent phosphorylation of mammalian protein phosphatase 1 by cdc2 kinase.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(6):2168-73.
1997: Nowicki S; Chen S L; Aizman O; Cheng X J; Li D; Nowicki C; Nairn A; Greengard P; Aperia A
20-Hydroxyeicosa-tetraenoic acid (20 HETE) activates protein kinase C. Role in regulation of rat renal Na+,K+-ATPase.
The Journal of clinical investigation 1997;99(6):1224-30.
1997: Oishi M; Nairn A C; Czernik A J; Lim G S; Isohara T; Gandy S E; Greengard P; Suzuki T
The cytoplasmic domain of Alzheimer's amyloid precursor protein is phosphorylated at Thr654, Ser655, and Thr668 in adult rat brain and cultured cells.
Molecular medicine (Cambridge, Mass.) 1997;3(2):111-23.
1996: Kaplitt M; Gouras G K; Makimura H; Jovanovic J; Sweeney D; Greengard P; Relkin N R; Gandy S
Apolipoprotein E, A beta-amyloid, and the molecular pathology of Alzheimer's disease. Therapeutic implications.
Annals of the New York Academy of Sciences 1996;802():42-9.
1996: Ikin A F; Annaert W G; Takei K; De Camilli P; Jahn R; Greengard P; Buxbaum J D
Alzheimer amyloid protein precursor is localized in nerve terminal preparations to Rab5-containing vesicular organelles distinct from those implicated in the synaptic vesicle pathway.
The Journal of biological chemistry 1996;271(50):31783-6.
1996: Lu B; Czernik A J; Popov S; Wang T; Poo M M; Greengard P
Expression of synapsin I correlates with maturation of the neuromuscular synapse.
Neuroscience 1996;74(4):1087-97.
1996: Desdouits F; Buxbaum J D; Desdouits-Magnen J; Nairn A C; Greengard P
Amyloid alpha peptide formation in cell-free preparations. Regulation by protein kinase C, calmodulin, and calcineurin.
The Journal of biological chemistry 1996;271(40):24670-4.
1996: Ryan T A; Li L; Chin L S; Greengard P; Smith S J
Synaptic vesicle recycling in synapsin I knock-out mice.
The Journal of cell biology 1996;134(5):1219-27.
1996: Logvinenko N S; Dulubova I; Fedosova N; Larsson S H; Nairn A C; Esmann M; Greengard P; Aperia A
Phosphorylation by protein kinase C of serine-23 of the alpha-1 subunit of rat Na+,K(+)-ATPase affects its conformational equilibrium.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(17):9132-7.
1996: Qian Y; Chao D S; Santillano D R; Cornwell T L; Nairn A C; Greengard P; Lincoln T M; Bredt D S
cGMP-dependent protein kinase in dorsal root ganglion: relationship with nitric oxide synthase and nociceptive neurons.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1996;16(10):3130-8.
1996: Xu H; Sweeney D; Greengard P; Gandy S
Metabolism of Alzheimer beta-amyloid precursor protein: regulation by protein kinase A in intact cells and in a cell-free system.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(9):4081-4.
1996: Jovanovic J N; Benfenati F; Siow Y L; Sihra T S; Sanghera J S; Pelech S L; Greengard P; Czernik A J
Neurotrophins stimulate phosphorylation of synapsin I by MAP kinase and regulate synapsin I-actin interactions.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(8):3679-83.
1996: Smith G D; Wolf D P; Trautman K C; da Cruz e Silva E F; Greengard P; Vijayaraghavan S
Primate sperm contain protein phosphatase 1, a biochemical mediator of motility.
Biology of reproduction 1996;54(3):719-27.
1996: Vijayaraghavan S; Stephens D T; Trautman K; Smith G D; Khatra B; da Cruz e Silva E F; Greengard P
Sperm motility development in the epididymis is associated with decreased glycogen synthase kinase-3 and protein phosphatase 1 activity.
Biology of reproduction 1996;54(3):709-18.
1996: Zhou Z; Smith J D; Greengard P; Gandy S
Alzheimer amyloid-beta peptide forms denaturant-resistant complex with type epsilon 3 but not type epsilon 4 isoform of native apolipoprotein E.
Molecular medicine (Cambridge, Mass.) 1996;2(2):175-80.
1996: Buxbaum J D; Greengard P
Regulation of APP processing by intra- and intercellular signals.
Annals of the New York Academy of Sciences 1996;777():327-31.
1996: Ferreira A; Li L; Chin L S; Greengard P; Kosik K S
Postsynaptic element contributes to the delay in synaptogenesis in synapsin I-deficient neurons.
Molecular and cellular neurosciences 1996;8(4):286-99.
1995: Li D; Aperia A; Celsi G; da Cruz e Silva E F; Greengard P; Meister B
Protein phosphatase-1 in the kidney: evidence for a role in the regulation of medullary Na(+)-K(+)-ATPase.
The American journal of physiology 1995;269(5 Pt 2):F673-80.
1995: Nielander H B; Onofri F; Valtorta F; Schiavo G; Montecucco C; Greengard P; Benfenati F
Phosphorylation of VAMP/synaptobrevin in synaptic vesicles by endogenous protein kinases.
Journal of neurochemistry 1995;65(4):1712-20.
1995: Xu H; Greengard P; Gandy S
Regulated formation of Golgi secretory vesicles containing Alzheimer beta-amyloid precursor protein.
The Journal of biological chemistry 1995;270(40):23243-5.
1995: Li L; Chin L S; Shupliakov O; Brodin L; Sihra T S; Hvalby O; Jensen V; Zheng D; McNamara J O; Greengard P
Impairment of synaptic vesicle clustering and of synaptic transmission, and increased seizure propensity, in synapsin I-deficient mice.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(20):9235-9.
1995: Chin L S; Li L; Ferreira A; Kosik K S; Greengard P
Impairment of axonal development and of synaptogenesis in hippocampal neurons of synapsin I-deficient mice.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(20):9230-4.
1995: Ferreira A; Han H Q; Greengard P; Kosik K S
Suppression of synapsin II inhibits the formation and maintenance of synapses in hippocampal culture.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(20):9225-9.
1995: Goldberg J; Huang H B; Kwon Y G; Greengard P; Nairn A C; Kuriyan J
Three-dimensional structure of the catalytic subunit of protein serine/threonine phosphatase-1.
Nature 1995;376(6543):745-53.
1995: Li L; Chin L S; Greengard P; Copeland N G; Gilbert D J; Jenkins N A
Localization of the synapsin II (SYN2) gene to human chromosome 3 and mouse chromosome 6.
Genomics 1995;28(2):365-6.
1995: da Cruz e Silva E F; da Cruz e Silva O A; Zaia C T; Greengard P
Inhibition of protein phosphatase 1 stimulates secretion of Alzheimer amyloid precursor protein.
Molecular medicine (Cambridge, Mass.) 1995;1(5):535-41.
1995: Pieribone V A; Shupliakov O; Brodin L; Hilfiker-Rothenfluh S; Czernik A J; Greengard P
Distinct pools of synaptic vesicles in neurotransmitter release.
Nature 1995;375(6531):493-7.
1995: Fried G; Han H Q; Meister B; Hökfelt T; Greengard P
Laminin and neuropeptide Y are increased by synapsin transfection in cultured NG108-15 neuroblastoma/glioma hybrid cells.
Journal of neurochemistry 1995;64(6):2674-80.
1995: da Cruz e Silva E F; Fox C A; Ouimet C C; Gustafson E; Watson S J; Greengard P
Differential expression of protein phosphatase 1 isoforms in mammalian brain.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1995;15(5 Pt 1):3375-89.
1995: Ouimet C C; da Cruz e Silva E F; Greengard P
The alpha and gamma 1 isoforms of protein phosphatase 1 are highly and specifically concentrated in dendritic spines.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(8):3396-400.
1995: Desdouits F; Cohen D; Nairn A C; Greengard P; Girault J A
Phosphorylation of DARPP-32, a dopamine- and cAMP-regulated phosphoprotein, by casein kinase I in vitro and in vivo.
The Journal of biological chemistry 1995;270(15):8772-8.
1995: Ceccaldi P E; Grohovaz F; Benfenati F; Chieregatti E; Greengard P; Valtorta F
Dephosphorylated synapsin I anchors synaptic vesicles to actin cytoskeleton: an analysis by videomicroscopy.
The Journal of cell biology 1995;128(5):905-12.
1995: Desdouits F; Siciliano J C; Greengard P; Girault J A
Dopamine- and cAMP-regulated phosphoprotein DARPP-32: phosphorylation of Ser-137 by casein kinase I inhibits dephosphorylation of Thr-34 by calcineurin.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(7):2682-5.
1995: Fisone G; Snyder G L; Fryckstedt J; Caplan M J; Aperia A; Greengard P
Na+,K(+)-ATPase in the choroid plexus. Regulation by serotonin/protein kinase C pathway.
The Journal of biological chemistry 1995;270(6):2427-30.
1995: Valtorta F; Iezzi N; Benfenati F; Lu B; Poo M M; Greengard P
Accelerated structural maturation induced by synapsin I at developing neuromuscular synapses of Xenopus laevis.
The European journal of neuroscience 1995;7(2):261-70.
1995: Surmeier D J; Bargas J; Hemmings H C; Nairn A C; Greengard P
Modulation of calcium currents by a D1 dopaminergic protein kinase/phosphatase cascade in rat neostriatal neurons.
Neuron 1995;14(2):385-97.
1995: Desdouits F; Cheetham J J; Huang H B; Kwon Y G; da Cruz e Silva E F; Denefle P; Ehrlich M E; Nairn A C; Greengard P; Girault J A
Mechanism of inhibition of protein phosphatase 1 by DARPP-32: studies with recombinant DARPP-32 and synthetic peptides.
Biochemical and biophysical research communications 1995;206(2):652-8.
1995: Alder J; Kanki H; Valtorta F; Greengard P; Poo M M
Overexpression of synaptophysin enhances neurotransmitter secretion at Xenopus neuromuscular synapses.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1995;15(1 Pt 2):511-9.
1995: Yamagata Y; Obata K; Greengard P; Czernik A J
Increase in synapsin I phosphorylation implicates a presynaptic component in septal kindling.
Neuroscience 1995;64(1):1-4.
1994: Snyder G L; Fisone G; Greengard P
Phosphorylation of DARPP-32 is regulated by GABA in rat striatum and substantia nigra.
Journal of neurochemistry 1994;63(5):1766-71.
1994: Chilcote T J; Siow Y L; Schaeffer E; Greengard P; Thiel G
Synapsin IIa bundles actin filaments.
Journal of neurochemistry 1994;63(4):1568-71.
1994: Ouimet C C; Baerwald K D; Gandy S E; Greengard P
Immunocytochemical localization of amyloid precursor protein in rat brain.
The Journal of comparative neurology 1994;348(2):244-60.
1994: Simonian N A; Elvhage T; Czernik A J; Greengard P; Hyman B T
Calcium/calmodulin-dependent protein kinase II immunostaining is preserved in Alzheimer's disease hippocampal neurons.
Brain research 1994;657(1-2):294-9.
1994: Han H Q; Greengard P
Remodeling of cytoskeletal architecture of nonneuronal cells induced by synapsin.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(18):8557-61.
1994: Näslund J; Schierhorn A; Hellman U; Lannfelt L; Roses A D; Tjernberg L O; Silberring J; Gandy S E; Winblad B; Greengard P
Relative abundance of Alzheimer A beta amyloid peptide variants in Alzheimer disease and normal aging.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(18):8378-82.
1994: Chin L S; Li L; Greengard P
Neuron-specific expression of the synapsin II gene is directed by a specific core promoter and upstream regulatory elements.
The Journal of biological chemistry 1994;269(28):18507-13.
1994: McPherson P S; Czernik A J; Chilcote T J; Onofri F; Benfenati F; Greengard P; Schlessinger J; De Camilli P
Interaction of Grb2 via its Src homology 3 domains with synaptic proteins including synapsin I.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(14):6486-90.
1994: Dohadwala M; da Cruz e Silva E F; Hall F L; Williams R T; Carbonaro-Hall D A; Nairn A C; Greengard P; Berndt N
Phosphorylation and inactivation of protein phosphatase 1 by cyclin-dependent kinases.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(14):6408-12.
1994: Buxbaum J D; Ruefli A A; Parker C A; Cypess A M; Greengard P
Calcium regulates processing of the Alzheimer amyloid protein precursor in a protein kinase C-independent manner.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(10):4489-93.
1994: Miles K; Audigier S S; Greengard P; Huganir R L
Autoregulation of phosphorylation of the nicotinic acetylcholine receptor.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1994;14(5 Pt 2):3271-9.
1994: Caporaso G L; Takei K; Gandy S E; Matteoli M; Mundigl O; Greengard P; De Camilli P
Morphologic and biochemical analysis of the intracellular trafficking of the Alzheimer beta/A4 amyloid precursor protein.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1994;14(5 Pt 2):3122-38.
1994: Ferreira A; Kosik K S; Greengard P; Han H Q
Aberrant neurites and synaptic vesicle protein deficiency in synapsin II-depleted neurons.
Science (New York, N.Y.) 1994;264(5161):977-9.
1994: Jaffe A B; Toran-Allerand C D; Greengard P; Gandy S E
Estrogen regulates metabolism of Alzheimer amyloid beta precursor protein.
The Journal of biological chemistry 1994;269(18):13065-8.
1994: Schaeffer E; Alder J; Greengard P; Poo M M
Synapsin IIa accelerates functional development of neuromuscular synapses.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(9):3882-6.
1994: Aperia A; Holtbäck U; Syrén M L; Svensson L B; Fryckstedt J; Greengard P
Activation/deactivation of renal Na+,K(+)-ATPase: a final common pathway for regulation of natriuresis.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1994;8(6):436-9.
1994: Suzuki T; Oishi M; Marshak D R; Czernik A J; Nairn A C; Greengard P
Cell cycle-dependent regulation of the phosphorylation and metabolism of the Alzheimer amyloid precursor protein.
The EMBO journal 1994;13(5):1114-22.
1994: Brené S; Lindefors N; Ehrlich M; Taubes T; Horiuchi A; Kopp J; Hall H; Sedvall G; Greengard P; Persson H
Expression of mRNAs encoding ARPP-16/19, ARPP-21, and DARPP-32 in human brain tissue.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1994;14(3 Pt 1):985-98.
1994: Gandy S; Caporaso G; Buxbaum J; Frangione B; Greengard P
APP processing, A beta-amyloidogenesis, and the pathogenesis of Alzheimer's disease.
Neurobiology of aging 1994;15(2):253-6.
1994: Greengard P; Benfenati F; Valtorta F
Synapsin I, an actin-binding protein regulating synaptic vesicle traffic in the nerve terminal.
Advances in second messenger and phosphoprotein research 1994;29():31-45.
1994: Gandy S; Greengard P
Processing of Alzheimer A beta-amyloid precursor protein: cell biology, regulation, and role in Alzheimer disease.
International review of neurobiology 1994;36():29-50.
1994: Gandy S; Greengard P
Regulated cleavage of the Alzheimer amyloid precursor protein: molecular and cellular basis.
Biochimie 1994;76(3-4):300-3.
1993: da Cruz e Silva O A; Iverfeldt K; Oltersdorf T; Sinha S; Lieberburg I; Ramabhadran T V; Suzuki T; Sisodia S S; Gandy S; Greengard P
Regulated cleavage of Alzheimer beta-amyloid precursor protein in the absence of the cytoplasmic tail.
Neuroscience 1993;57(4):873-7.
1993: Benfenati F; Valtorta F; Rossi M C; Onofri F; Sihra T; Greengard P
Interactions of synapsin I with phospholipids: possible role in synaptic vesicle clustering and in the maintenance of bilayer structures.
The Journal of cell biology 1993;123(6 Pt 2):1845-55.
1993: Buxbaum J D; Christensen J L; Ruefli A A; Greengard P; Loring J F
Expression of APP in brains of transgenic mice containing the entire human APP gene.
Biochemical and biophysical research communications 1993;197(2):639-45.
1993: Knops J; Gandy S; Greengard P; Lieberburg I; Sinha S
Serine phosphorylation of the secreted extracellular domain of APP.
Biochemical and biophysical research communications 1993;197(2):380-5.
1993: Snyder G L; Fisone G; Morino P; Gundersen V; Ottersen O P; Hökfelt T; Greengard P
Regulation by the neuropeptide cholecystokinin (CCK-8S) of protein phosphorylation in the neostriatum.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(23):11277-81.
1993: Neyroz P; Desdouits F; Benfenati F; Knutson J R; Greengard P; Girault J A
Study of the conformation of DARPP-32, a dopamine- and cAMP-regulated phosphoprotein, by fluorescence spectroscopy.
The Journal of biological chemistry 1993;268(32):24022-31.
1993: Buxbaum J D; Koo E H; Greengard P
Protein phosphorylation inhibits production of Alzheimer amyloid beta/A4 peptide.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(19):9195-8.
1993: Gandy S E; Caporaso G L; Buxbaum J D; de Cruz Silva O; Iverfeldt K; Nordstedt C; Suzuki T; Czernik A J; Nairn A C; Greengard P
Protein phosphorylation regulates relative utilization of processing pathways for Alzheimer beta/A4 amyloid precursor protein.
Annals of the New York Academy of Sciences 1993;695():117-21.
1993: Barbas H; Gustafson E L; Greengard P
Comparison of the immunocytochemical localization of DARPP-32 and I-1 in the amygdala and hippocampus of the rhesus monkey.
The Journal of comparative neurology 1993;334(1):1-18.
1993: Ceccaldi P E; Benfenati F; Chieregatti E; Greengard P; Valtorta F
Rapid binding of synapsin I to F- and G-actin. A study using fluorescence resonance energy transfer.
FEBS letters 1993;329(3):301-5.
1993: Iverfeldt K; Walaas S I; Greengard P
Altered processing of Alzheimer amyloid precursor protein in response to neuronal degeneration.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(9):4146-50.
1993: Lu B; Fu W M; Greengard P; Poo M M
Calcitonin gene-related peptide potentiates synaptic responses at developing neuromuscular junction.
Nature 1993;363(6424):76-9.
1993: Tsou K; Snyder G L; Greengard P
Nitric oxide/cGMP pathway stimulates phosphorylation of DARPP-32, a dopamine- and cAMP-regulated phosphoprotein, in the substantia nigra.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(8):3462-5.
1993: Tsou K; Girault J A; Greengard P
Dopamine D1 agonist SKF 38393 increases the state of phosphorylation of ARPP-21 in substantia nigra.
Journal of neurochemistry 1993;60(3):1043-6.
1993: Greengard P; Valtorta F; Czernik A J; Benfenati F
Synaptic vesicle phosphoproteins and regulation of synaptic function.
Science (New York, N.Y.) 1993;259(5096):780-5.
1993: Rubenstein J L; Greengard P; Czernik A J
Calcium-dependent serine phosphorylation of synaptophysin.
Synapse (New York, N.Y.) 1993;13(2):161-72.
1993: Li L; Suzuki T; Mori N; Greengard P
Identification of a functional silencer element involved in neuron-specific expression of the synapsin I gene.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(4):1460-4.
1993: Ramabhadran T V; Gandy S E; Ghiso J; Czernik A J; Ferris D; Bhasin R; Goldgaber D; Frangione B; Greengard P
Proteolytic processing of human amyloid beta protein precursor in insect cells. Major carboxyl-terminal fragment is identical to its human counterpart.
The Journal of biological chemistry 1993;268(3):2009-12.
1993: Nordstedt C; Caporaso G L; Thyberg J; Gandy S E; Greengard P
Identification of the Alzheimer beta/A4 amyloid precursor protein in clathrin-coated vesicles purified from PC12 cells.
The Journal of biological chemistry 1993;268(1):608-12.
1993: Ibarra F; Aperia A; Svensson L B; Eklöf A C; Greengard P
Bidirectional regulation of Na+,K(+)-ATPase activity by dopamine and an alpha-adrenergic agonist.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(1):21-4.
1993: Walaas S I; Greengard P
ARPP-39, a membrane-associated substrate for cyclic AMP-dependent protein kinase present in neostriatal neurons.
Journal of molecular neuroscience : MN 1993;4(2):73-88.
1992: Torri Tarelli F; Bossi M; Fesce R; Greengard P; Valtorta F
Synapsin I partially dissociates from synaptic vesicles during exocytosis induced by electrical stimulation.
Neuron 1992;9(6):1143-53.
1992: Gandy S E; Caporaso G L; Ramabhadran T V; Suzuki T; Buxbaum J D; Nordstedt C; Iverfeldt K; Czernik A J; Nairn A C; Greengard P
Characterization of alternative routes for processing of the Alzheimer beta/A4-amyloid precursor protein. Differential effects of phorbol esters and chloroquine.
Annals of the New York Academy of Sciences 1992;674():203-17.
1992: Gustafson E L; Ehrlich M E; Trivedi P; Greengard P
Developmental regulation of phosphoprotein gene expression in the caudate-putamen of rat: an in situ hybridization study.
Neuroscience 1992;51(1):65-75.
1992: Buxbaum J D; Oishi M; Chen H I; Pinkas-Kramarski R; Jaffe E A; Gandy S E; Greengard P
Cholinergic agonists and interleukin 1 regulate processing and secretion of the Alzheimer beta/A4 amyloid protein precursor.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(21):10075-8.
1992: Alder J; Xie Z P; Valtorta F; Greengard P; Poo M
Antibodies to synaptophysin interfere with transmitter secretion at neuromuscular synapses.
Neuron 1992;9(4):759-68.
1992: Benfenati F; Valtorta F; Rubenstein J L; Gorelick F S; Greengard P; Czernik A J
Synaptic vesicle-associated Ca2+/calmodulin-dependent protein kinase II is a binding protein for synapsin I.
Nature 1992;359(6394):417-20.
1992: Gandy S E; Buxbaum J D; Suzuki T; Ramabhadran T V; Caporaso G L; Nairn A C; Greengard P
The nature and metabolism of potentially amyloidogenic carboxyl-terminal fragments of the Alzheimer beta/A4-amyloid precursor protein: some technical notes.
Neurobiology of aging 1992;13(5):601-3.
1992: Hemmings H C; Girault J A; Nairn A C; Bertuzzi G; Greengard P
Distribution of protein phosphatase inhibitor-1 in brain and peripheral tissues of various species: comparison with DARPP-32.
Journal of neurochemistry 1992;59(3):1053-61.
1992: Ouimet C C; LaMantia A S; Goldman-Rakic P; Rakic P; Greengard P
Immunocytochemical localization of DARPP-32, a dopamine and cyclic-AMP-regulated phosphoprotein, in the primate brain.
The Journal of comparative neurology 1992;323(2):209-18.
1992: Snyder G L; Girault J A; Chen J Y; Czernik A J; Kebabian J W; Nathanson J A; Greengard P
Phosphorylation of DARPP-32 and protein phosphatase inhibitor-1 in rat choroid plexus: regulation by factors other than dopamine.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1992;12(8):3071-83.
1992: Aperia A; Ibarra F; Svensson L B; Klee C; Greengard P
Calcineurin mediates alpha-adrenergic stimulation of Na+,K(+)-ATPase activity in renal tubule cells.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(16):7394-7.
1992: Alder J; Lu B; Valtorta F; Greengard P; Poo M M
Calcium-dependent transmitter secretion reconstituted in Xenopus oocytes: requirement for synaptophysin.
Science (New York, N.Y.) 1992;257(5070):657-61.
1992: Suzuki T; Nairn A C; Gandy S E; Greengard P
Phosphorylation of Alzheimer amyloid precursor protein by protein kinase C.
Neuroscience 1992;48(4):755-61.
1992: Fesce R; Benfenati F; Greengard P; Valtorta F
Effects of the neuronal phosphoprotein synapsin I on actin polymerization. II. Analytical interpretation of kinetic curves.
The Journal of biological chemistry 1992;267(16):11289-99.
1992: Picciotto M R; Cohn J A; Bertuzzi G; Greengard P; Nairn A C
Phosphorylation of the cystic fibrosis transmembrane conductance regulator.
The Journal of biological chemistry 1992;267(18):12742-52.
1992: Valtorta F; Greengard P; Fesce R; Chieregatti E; Benfenati F
Effects of the neuronal phosphoprotein synapsin I on actin polymerization. I. Evidence for a phosphorylation-dependent nucleating effect.
The Journal of biological chemistry 1992;267(16):11281-8.
1992: Mandell J W; Czernik A J; De Camilli P; Greengard P; Townes-Anderson E
Differential expression of synapsins I and II among rat retinal synapses.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1992;12(5):1736-49.
1992: Siow Y L; Chilcote T J; Benfenati F; Greengard P; Thiel G
Synapsin IIa: expression in insect cells, purification, and characterization.
Biochemistry 1992;31(17):4268-75.
1992: Valtorta F; Benfenati F; Greengard P
Structure and function of the synapsins.
The Journal of biological chemistry 1992;267(11):7195-8.
1992: Caporaso G L; Gandy S E; Buxbaum J D; Ramabhadran T V; Greengard P
Protein phosphorylation regulates secretion of Alzheimer beta/A4 amyloid precursor protein.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(7):3055-9.
1992: Gandy S; Greengard P
Amyloidogenesis in Alzheimer's disease: some possible therapeutic opportunities.
Trends in pharmacological sciences 1992;13(3):108-13.
1992: Caporaso G L; Gandy S E; Buxbaum J D; Greengard P
Chloroquine inhibits intracellular degradation but not secretion of Alzheimer beta/A4 amyloid precursor protein.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(6):2252-6.
1992: Lu B; Greengard P; Poo M M
Exogenous synapsin I promotes functional maturation of developing neuromuscular synapses.
Neuron 1992;8(3):521-9.
1992: Benfenati F; Valtorta F; Chieregatti E; Greengard P
Interaction of free and synaptic vesicle-bound synapsin I with F-actin.
Neuron 1992;8(2):377-86.
1992: Girault J A; Chamak B; Bertuzzi G; Tixier H; Wang J K; Pang D T; Greengard P
Protein phosphotyrosine in mouse brain: developmental changes and regulation by epidermal growth factor, type I insulin-like growth factor, and insulin.
Journal of neurochemistry 1992;58(2):518-28.
1992: Nichols R A; Chilcote T J; Czernik A J; Greengard P
Synapsin I regulates glutamate release from rat brain synaptosomes.
Journal of neurochemistry 1992;58(2):783-5.
1992: Gandy S E; Bhasin R; Ramabhadran T V; Koo E H; Price D L; Goldgaber D; Greengard P
Alzheimer beta/A4-amyloid precursor protein: evidence for putative amyloidogenic fragment.
Journal of neurochemistry 1992;58(1):383-6.
1991: Ehrlich M E; Greengard P
Characterization of rat ARPP-21 mRNA: sequence analysis, tissue distribution, and regulation.
Journal of neurochemistry 1991;57(6):1985-91.
1991: Bertorello A M; Aperia A; Walaas S I; Nairn A C; Greengard P
Phosphorylation of the catalytic subunit of Na+,K(+)-ATPase inhibits the activity of the enzyme.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(24):11359-62.
1991: Nordstedt C; Gandy S E; Alafuzoff I; Caporaso G L; Iverfeldt K; Grebb J A; Winblad B; Greengard P
Alzheimer beta/A4 amyloid precursor protein in human brain: aging-associated increases in holoprotein and in a proteolytic fragment.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(20):8910-4.
1991: Meister B; Schultzberg M; Hemmings H C; Greengard P; Goldstein M; Hökfelt T
Dopamine- and adenosine-3',5'-monophosphate (cAMP)-regulated phosphoprotein of 32 kDa (DARPP-32) in the adrenal gland: immunohistochemical localization.
Journal of the autonomic nervous system 1991;36(1):75-84.
1991: Walaas S I; Greengard P
Protein phosphorylation and neuronal function.
Pharmacological reviews 1991;43(3):299-349.
1991: Meister B; Arvidsson U; Hemmings H C; Greengard P; Hökfelt T
Dopamine- and adenosine-3':5'-monophosphate (cAMP)-regulated phosphoprotein of Mr 32,000 (DARPP-32) in the retina of cat, monkey and human.
Neuroscience letters 1991;131(1):66-70.
1991: Greengard P; Jen J; Nairn A C; Stevens C F
Enhancement of the glutamate response by cAMP-dependent protein kinase in hippocampal neurons.
Science (New York, N.Y.) 1991;253(5024):1135-8.
1991: Meister B; Askergren J; Tunevall G; Hemmings H C; Greengard P
Identification of a dopamine- and 3'5'-cyclic adenosine monophosphate-regulated phosphoprotein of 32 kD (DARPP-32) in parathyroid hormone-producing cells of the human parathyroid gland.
Journal of endocrinological investigation 1991;14(8):655-61.
1991: Bähler M; Klein R L; Wang J K; Benfenati F; Greengard P
A novel synaptic vesicle-associated phosphoprotein: SVAPP-120.
Journal of neurochemistry 1991;57(2):423-30.
1991: Gustafson E L; Girault J A; Hemmings H C; Nairn A C; Greengard P
Immunocytochemical localization of phosphatase inhibitor-1 in rat brain.
The Journal of comparative neurology 1991;310(2):170-88.
1991: Yamagata Y; Czernik A J; Greengard P
Active catalytic fragment of Ca2+/calmodulin-dependent protein kinase II. Purification, characterization, and structural analysis.
The Journal of biological chemistry 1991;266(23):15391-7.
1991: Piomelli D; Greengard P
Bidirectional control of phospholipase A2 activity by Ca2+/calmodulin-dependent protein kinase II, cAMP-dependent protein kinase, and casein kinase II.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(15):6770-4.
1991: Lüthi T; Haltiwanger R S; Greengard P; Bähler M
Synapsins contain O-linked N-acetylglucosamine.
Journal of neurochemistry 1991;56(5):1493-8.
1991: Llinás R; Gruner J A; Sugimori M; McGuinness T L; Greengard P
Regulation by synapsin I and Ca(2+)-calmodulin-dependent protein kinase II of the transmitter release in squid giant synapse.
The Journal of physiology 1991;436():257-82.
1991: Thiel G; Greengard P; Südhof T C
Characterization of tissue-specific transcription by the human synapsin I gene promoter.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(8):3431-5.
1991: Aperia A; Fryckstedt J; Svensson L; Hemmings H C; Nairn A C; Greengard P
Phosphorylated Mr 32,000 dopamine- and cAMP-regulated phosphoprotein inhibits Na+,K(+)-ATPase activity in renal tubule cells.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(7):2798-801.
1991: Ho M F; Bähler M; Czernik A J; Schiebler W; Kézdy F J; Kaiser E T; Greengard P
Synapsin I is a highly surface-active molecule.
The Journal of biological chemistry 1991;266(9):5600-7.
1991: Han H Q; Nichols R A; Rubin M R; Bähler M; Greengard P
Induction of formation of presynaptic terminals in neuroblastoma cells by synapsin IIb.
Nature 1991;349(6311):697-700.
1991: Benfenati F; Valtorta F; Greengard P
Computer modeling of synapsin I binding to synaptic vesicles and F-actin: implications for regulation of neurotransmitter release.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(2):575-9.
1991: Czernik A J; Girault J A; Nairn A C; Chen J; Snyder G; Kebabian J; Greengard P
Production of phosphorylation state-specific antibodies.
Methods in enzymology 1991;201():264-83.
1990: Grebb J A; Greengard P
An analysis of synapsin II, a neuronal phosphoprotein, in postmortem brain tissue from alcoholic and neuropsychiatrically ill adults and medically ill children and young adults.
Archives of general psychiatry 1990;47(12):1149-56.
1990: Hemmings H C; Nairn A C; Elliott J I; Greengard P
Synthetic peptide analogs of DARPP-32 (Mr 32,000 dopamine- and cAMP-regulated phosphoprotein), an inhibitor of protein phosphatase-1. Phosphorylation, dephosphorylation, and inhibitory activity.
The Journal of biological chemistry 1990;265(33):20369-76.
1990: Girault J A; Hemmings H C; Zorn S H; Gustafson E L; Greengard P
Characterization in mammalian brain of a DARPP-32 serine kinase identical to casein kinase II.
Journal of neurochemistry 1990;55(5):1772-83.
1990: Lin J W; Sugimori M; Llinás R R; McGuinness T L; Greengard P
Effects of synapsin I and calcium/calmodulin-dependent protein kinase II on spontaneous neurotransmitter release in the squid giant synapse.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(21):8257-61.
1990: Huganir R L; Greengard P
Regulation of neurotransmitter receptor desensitization by protein phosphorylation.
Neuron 1990;5(5):555-67.
1990: Berger B; Febvret A; Greengard P; Goldman-Rakic P S
DARPP-32, a phosphoprotein enriched in dopaminoceptive neurons bearing dopamine D1 receptors: distribution in the cerebral cortex of the newborn and adult rhesus monkey.
The Journal of comparative neurology 1990;299(3):327-48.
1990: Sáez J C; Nairn A C; Czernik A J; Spray D C; Hertzberg E L; Greengard P; Bennett M V
Phosphorylation of connexin 32, a hepatocyte gap-junction protein, by cAMP-dependent protein kinase, protein kinase C and Ca2+/calmodulin-dependent protein kinase II.
European journal of biochemistry / FEBS 1990;192(2):263-73.
1990: Halpain S; Greengard P
Activation of NMDA receptors induces rapid dephosphorylation of the cytoskeletal protein MAP2.
Neuron 1990;5(3):237-46.
1990: Piomelli D; Greengard P
Lipoxygenase metabolites of arachidonic acid in neuronal transmembrane signalling.
Trends in pharmacological sciences 1990;11(9):367-73.
1990: Thiel G; Südhof T C; Greengard P
Synapsin II. Mapping of a domain in the NH2-terminal region which binds to small synaptic vesicles.
The Journal of biological chemistry 1990;265(27):16527-33.
1990: Bertorello A M; Hopfield J F; Aperia A; Greengard P
Inhibition by dopamine of (Na(+)+K+)ATPase activity in neostriatal neurons through D1 and D2 dopamine receptor synergism.
Nature 1990;347(6291):386-8.
1990: Buxbaum J D; Gandy S E; Cicchetti P; Ehrlich M E; Czernik A J; Fracasso R P; Ramabhadran T V; Unterbeck A J; Greengard P
Processing of Alzheimer beta/A4 amyloid precursor protein: modulation by agents that regulate protein phosphorylation.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(15):6003-6.
1990: Girault J A; Halpain S; Greengard P
Excitatory amino acid antagonists and Parkinson's disease.
Trends in neurosciences 1990;13(8):325-7.
1990: Sugrue M M; Brugge J S; Marshak D R; Greengard P; Gustafson E L
Immunocytochemical localization of the neuron-specific form of the c-src gene product, pp60c-src(+), in rat brain.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1990;10(8):2513-27.
1990: Grebb J A; Girault J A; Ehrlich M; Greengard P
Chronic treatment of rats with SCH-23390 or raclopride does not affect the concentrations of DARPP-32 or its mRNA in dopamine-innervated brain regions.
Journal of neurochemistry 1990;55(1):204-7.
1990: Benfenati F; Neyroz P; Bähler M; Masotti L; Greengard P
Time-resolved fluorescence study of the neuron-specific phosphoprotein synapsin I. Evidence for phosphorylation-dependent conformational changes.
The Journal of biological chemistry 1990;265(21):12584-95.
1990: Mandell J W; Townes-Anderson E; Czernik A J; Cameron R; Greengard P; De Camilli P
Synapsins in the vertebrate retina: absence from ribbon synapses and heterogeneous distribution among conventional synapses.
Neuron 1990;5(1):19-33.
1990: Ehrlich M E; Rosen N L; Kurihara T; Shalaby I A; Greengard P
DARPP-32 development in the caudate nucleus is independent of afferent input from the substantia nigra.
Brain research. Developmental brain research 1990;54(2):257-63.
1990: Horiuchi A; Williams K R; Kurihara T; Nairn A C; Greengard P
Purification and cDNA cloning of ARPP-16, a cAMP-regulated phosphoprotein enriched in basal ganglia, and of a related phosphoprotein, ARPP-19.
The Journal of biological chemistry 1990;265(16):9476-84.
1990: Bähler M; Benfenati F; Valtorta F; Greengard P
The synapsins and the regulation of synaptic function.
BioEssays : news and reviews in molecular, cellular and developmental biology 1990;12(6):259-63.
1990: Ouimet C C; Wang J K; Walaas S I; Albert K A; Greengard P
Localization of the MARCKS (87 kDa) protein, a major specific substrate for protein kinase C, in rat brain.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1990;10(5):1683-98.
1990: Girault J A; Horiuchi A; Gustafson E L; Rosen N L; Greengard P
Differential expression of ARPP-16 and ARPP-19, two highly related cAMP-regulated phosphoproteins, one of which is specifically associated with dopamine-innervated brain regions.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1990;10(4):1124-33.
1990: Schalling M; Dagerlind A; Goldstein M; Ehrlich M; Greengard P; Hökfelt T
Comparison of gene expression of the dopamine D-2 receptor and DARPP-32 in rat brain, pituitary and adrenal gland.
European journal of pharmacology 1990;188(4-5):277-81.
1990: Ouimet C C; Greengard P
Distribution of DARPP-32 in the basal ganglia: an electron microscopic study.
Journal of neurocytology 1990;19(1):39-52.
1990: Schalling M; Djurfeldt M; Hökfelt T; Ehrlich M; Kurihara T; Greengard P
Distribution and cellular localization of DARPP-32 mRNA in rat brain.
Brain research. Molecular brain research 1990;7(2):139-49.
1990: Nichols R A; Sihra T S; Czernik A J; Nairn A C; Greengard P
Calcium/calmodulin-dependent protein kinase II increases glutamate and noradrenaline release from synaptosomes.
Nature 1990;343(6259):647-51.
1990: Torri-Tarelli F; Villa A; Valtorta F; De Camilli P; Greengard P; Ceccarelli B
Redistribution of synaptophysin and synapsin I during alpha-latrotoxin-induced release of neurotransmitter at the neuromuscular junction.
The Journal of cell biology 1990;110(2):449-59.
1990: Halpain S; Girault J A; Greengard P
Activation of NMDA receptors induces dephosphorylation of DARPP-32 in rat striatal slices.
Nature 1990;343(6256):369-72.
1990: De Camilli P; Benfenati F; Valtorta F; Greengard P
The synapsins.
Annual review of cell biology 1990;6():433-60.
1990: Ehrlich M E; Kurihara T; Greengard P
Rat DARPP-32: cloning, sequencing, and characterization of the cDNA.
Journal of molecular neuroscience : MN 1990;2(1):1-10.
1990: Gustafson E L; Greengard P
Localization of DARPP-32 immunoreactive neurons in the bed nucleus of the stria terminalis and central nucleus of the amygdala: co-distribution with axons containing tyrosine hydroxylase, vasoactive intestinal polypeptide, and calcitonin gene-related peptide.
Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale 1990;79(3):447-58.
1990: Girault J A; Walaas S I; Hemmings H C; Greengard P
ARPP-21, a cAMP-regulated phosphoprotein enriched in dopamine-innervated brain regions: tissue distribution and regulation of phosphorylation in rat brain.
Neuroscience 1990;37(2):317-25.
1989: Girault J A; Hemmings H C; Williams K R; Nairn A C; Greengard P
Phosphorylation of DARPP-32, a dopamine- and cAMP-regulated phosphoprotein, by casein kinase II.
The Journal of biological chemistry 1989;264(36):21748-59.
1989: Valtorta F; Tarelli F T; Campanati L; Villa A; Greengard P
Synaptophysin and synapsin I as tools for the study of the exo-endocytotic cycle.
Cell biology international reports 1989;13(12):1023-38.
1989: Benfenati F; Valtorta F; Bähler M; Greengard P
Synapsin I, a neuron-specific phosphoprotein interacting with small synaptic vesicles and F-actin.
Cell biology international reports 1989;13(12):1007-21.
1989: Navone F; Di Gioia G; Jahn R; Browning M; Greengard P; De Camilli P
Microvesicles of the neurohypophysis are biochemically related to small synaptic vesicles of presynaptic nerve terminals.
The Journal of cell biology 1989;109(6 Pt 2):3425-33.
1989: McGuinness T L; Brady S T; Gruner J A; Sugimori M; Llinas R; Greengard P
Phosphorylation-dependent inhibition by synapsin I of organelle movement in squid axoplasm.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1989;9(12):4138-49.
1989: Meister B; Villar M J; Schalling M; Ehrlich M; Greengard P; Hökfelt T
Demonstration of DARPP-32 in pituicytes of the neurohypophysis-decreased expression after administration of hyperosmotic stimuli.
Acta physiologica Scandinavica 1989;137(3):461-2.
1989: Won L; Price S; Wainer B H; Hoffmann P C; Bolam J P; Greengard P; Heller A
Correlated light and electron microscopic study of dopaminergic neurons and their synaptic junctions with DARPP-32-containing cells in three-dimensional reaggregate tissue culture.
The Journal of comparative neurology 1989;289(1):165-77.
1989: Piomelli D; Wang J K; Sihra T S; Nairn A C; Czernik A J; Greengard P
Inhibition of Ca2+/calmodulin-dependent protein kinase II by arachidonic acid and its metabolites.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(21):8550-4.
1989: Walaas S I; Wang J K; Albert K A; Greengard P
Calcium/diacylglycerol-dependent protein kinase and its major 87-kilodalton protein substrate are differentially distributed in rat basal ganglia.
Journal of neurochemistry 1989;53(4):1199-202.
1989: Grebb J A; Browning M D; Valverius P; Borg S; Sedvall G; Greengard P
An analysis of postmortem brain samples from 32 alcoholic and nonalcoholic individuals for protein III, a neuronal phosphoprotein.
Alcoholism, clinical and experimental research 1989;13(5):673-9.
1989: Meister B; Fryckstedt J; Schalling M; Cortés R; Hökfelt T; Aperia A; Hemmings H C; Nairn A C; Ehrlich M; Greengard P
Dopamine- and cAMP-regulated phosphoprotein (DARPP-32) and dopamine DA1 agonist-sensitive Na+,K+-ATPase in renal tubule cells.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(20):8068-72.
1989: Kurihara T; Ehrlich M E; Horiuchi J; Nasu T; Greengard P
ARPP-21, a cyclic AMP-regulated phosphoprotein enriched in dopamine-innervated brain regions. II. Molecular cloning and nucleotide sequence.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1989;9(10):3638-44.
1989: Williams K R; Hemmings H C; LoPresti M B; Greengard P
ARPP-21, a cyclic AMP-regulated phosphoprotein enriched in dopamine-innervated brain regions. I. Amino acid sequence of ARPP-21B from bovine caudate nucleus.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1989;9(10):3631-7.
1989: Sihra T S; Wang J K; Gorelick F S; Greengard P
Translocation of synapsin I in response to depolarization of isolated nerve terminals.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(20):8108-12.
1989: Girault J A; Gorelick F S; Greengard P
Improving the quality of immunoblots by chromatography of polyclonal antisera on keratin affinity columns.
Analytical biochemistry 1989;182(1):193-6.
1989: Bahinski A; Nairn A C; Greengard P; Gadsby D C
Chloride conductance regulated by cyclic AMP-dependent protein kinase in cardiac myocytes.
Nature 1989;340(6236):718-21.
1989: Gustafson E L; Ouimet C C; Greengard P
Spatial relationship of the striatonigral and mesostriatal pathways: double-label immunocytochemistry for DARPP-32 and tyrosine hydroxylase.
Brain research 1989;491(2):297-306.
1989: Stumpo D J; Graff J M; Albert K A; Greengard P; Blackshear P J
Molecular cloning, characterization, and expression of a cDNA encoding the "80- to 87-kDa" myristoylated alanine-rich C kinase substrate: a major cellular substrate for protein kinase C.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(11):4012-6.
1989: Rosen A; Nairn A C; Greengard P; Cohn Z A; Aderem A
Bacterial lipopolysaccharide regulates the phosphorylation of the 68K protein kinase C substrate in macrophages.
The Journal of biological chemistry 1989;264(16):9118-21.
1989: Mackie K; Sorkin B C; Nairn A C; Greengard P; Edelman G M; Cunningham B A
Identification of two protein kinases that phosphorylate the neural cell-adhesion molecule, N-CAM.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1989;9(6):1883-96.
1989: Li M; McCann J D; Anderson M P; Clancy J P; Liedtke C M; Nairn A C; Greengard P; Welsch M J
Regulation of chloride channels by protein kinase C in normal and cystic fibrosis airway epithelia.
Science (New York, N.Y.) 1989;244(4910):1353-6.
1989: Stumpo D J; Graff J M; Albert K A; Greengard P; Blackshear P J
Nucleotide sequence of a cDNA for the bovine myristoylated alanine-rich C kinase substrate (MARCKS).
Nucleic acids research 1989;17(10):3987-8.
1989: Miles K; Greengard P; Huganir R L
Calcitonin gene-related peptide regulates phosphorylation of the nicotinic acetylcholine receptor in rat myotubes.
Neuron 1989;2(5):1517-24.
1989: Hemmings H C; Girault J A; Williams K R; LoPresti M B; Greengard P
ARPP-21, a cyclic AMP-regulated phosphoprotein (Mr = 21,000) enriched in dopamine-innervated brain regions. Amino acid sequence of the site phosphorylated by cyclic AMP in intact cells and kinetic studies of its phosphorylation in vitro.
The Journal of biological chemistry 1989;264(13):7726-33.
1989: Benfenati F; Bähler M; Jahn R; Greengard P
Interactions of synapsin I with small synaptic vesicles: distinct sites in synapsin I bind to vesicle phospholipids and vesicle proteins.
The Journal of cell biology 1989;108(5):1863-72.
1989: Benfenati F; Greengard P; Brunner J; Bähler M
Electrostatic and hydrophobic interactions of synapsin I and synapsin I fragments with phospholipid bilayers.
The Journal of cell biology 1989;108(5):1851-62.
1989: Bähler M; Benfenati F; Valtorta F; Czernik A J; Greengard P
Characterization of synapsin I fragments produced by cysteine-specific cleavage: a study of their interactions with F-actin.
The Journal of cell biology 1989;108(5):1841-9.
1989: Girault J A; Raisman-Vozari R; Agid Y; Greengard P
Striatal phosphoproteins in Parkinson disease and progressive supranuclear palsy.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(7):2493-7.
1989: Wang J K; Walaas S I; Sihra T S; Aderem A; Greengard P
Phosphorylation and associated translocation of the 87-kDa protein, a major protein kinase C substrate, in isolated nerve terminals.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(7):2253-6.
1989: Walaas S I; Cala S; Greengard P
Localization of ARPP-90, a major 90 kiloDalton basal ganglion-enriched substrate for cyclic AMP-dependent protein kinase, in striatonigral neurons in the rat brain.
Brain research. Molecular brain research 1989;5(2):149-57.
1989: Strålfors P; Hemmings H C; Greengard P
Inhibitors of protein phosphatase-1. Inhibitor-1 of bovine adipose tissue and a dopamine- and cAMP-regulated phosphoprotein of bovine brain are identical.
European journal of biochemistry / FEBS 1989;180(1):143-8.
1989: Ouimet C C; Hemmings H C; Greengard P
ARPP-21, a cyclic AMP-regulated phosphoprotein enriched in dopamine-innervated brain regions. II. Immunocytochemical localization in rat brain.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1989;9(3):865-75.
1989: Hemmings H C; Greengard P
ARPP-21, a cyclic AMP-regulated phosphoprotein enriched in dopamine-innervated brain regions. I. Purification and characterization of the protein from bovine caudate nucleus.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1989;9(3):851-64.
1989: Hemmings H C; Nairn A C; McGuinness T L; Huganir R L; Greengard P
Role of protein phosphorylation in neuronal signal transduction.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1989;3(5):1583-92.
1989: Conn P J; Strong J A; Azhderian E M; Nairn A C; Greengard P; Kaczmarek L K
Protein kinase inhibitors selectively block phorbol ester- or forskolin-induced changes in excitability of Aplysia neurons.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1989;9(2):473-9.
1989: Nichols R A; Wu W C; Haycock J W; Greengard P
Introduction of impermeant molecules into synaptosomes using freeze/thaw permeabilization.
Journal of neurochemistry 1989;52(2):521-9.
1989: Walaas S I; Perdahl-Wallace E; Winblad B; Greengard P
Protein phosphorylation systems in postmortem human brain.
Journal of molecular neuroscience : MN 1989;1(2):105-16.
1989: Walaas S I; Girault J A; Greengard P
Localization of cyclic GMP-dependent protein kinase in rat basal ganglia neurons.
Journal of molecular neuroscience : MN 1989;1(4):243-50.
1989: Walaas S I; Gorelick F S; Greengard P
Presence of calcium/calmodulin-dependent protein kinase II in nerve terminals of rat brain.
Synapse (New York, N.Y.) 1989;3(4):356-62.
1989: Walaas S I; Sedvall G; Greengard P
Dopamine-regulated phosphorylation of synaptic vesicle-associated proteins in rat neostriatum and substantia nigra.
Neuroscience 1989;29(1):9-19.
1988: Hopfield J F; Tank D W; Greengard P; Huganir R L
Functional modulation of the nicotinic acetylcholine receptor by tyrosine phosphorylation.
Nature 1988;336(6200):677-80.
1988: Valtorta F; Jahn R; Fesce R; Greengard P; Ceccarelli B
Synaptophysin (p38) at the frog neuromuscular junction: its incorporation into the axolemma and recycling after intense quantal secretion.
The Journal of cell biology 1988;107(6 Pt 2):2717-27.
1988: Agnati L F; Fuxe K; Zoli M; Ferraguti F; Benfenati F; Ouimet C C; Walaas S I; Hemmings H C; Goldstein M; Greengard P
Morphometrical evidence for a complex organization of tyrosine hydroxylase-, enkephalin- and DARPP-32-like immunoreactive patches and their codistribution at three rostrocaudal levels in the rat neostriatum.
Neuroscience 1988;27(3):785-97.
1988: Meister B; Hökfelt T; Tsuruo Y; Hemmings H; Ouimet C; Greengard P; Goldstein M
DARPP-32, a dopamine- and cyclic AMP-regulated phosphoprotein in tanycytes of the mediobasal hypothalamus: distribution and relation to dopamine and luteinizing hormone-releasing hormone neurons and other glial elements.
Neuroscience 1988;27(2):607-22.
1988: Walaas S I; Lai Y; Gorelick F S; DeCamilli P; Moretti M; Greengard P
Cell-specific localization of the alpha-subunit of calcium/calmodulin-dependent protein kinase II in Purkinje cells in rodent cerebellum.
Brain research 1988;464(3):233-42.
1988: Meister B; Fried G; Hökfelt T; Hemmings H C; Greengard P
Immunohistochemical evidence for the existence of a dopamine- and cyclic AMP-regulated phosphoprotein (DARPP-32) in brown adipose tissue of pigs.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(22):8713-6.
1988: Gorelick F S; Wang J K; Lai Y; Nairn A C; Greengard P
Autophosphorylation and activation of Ca2+/calmodulin-dependent protein kinase II in intact nerve terminals.
The Journal of biological chemistry 1988;263(33):17209-12.
1988: Walaas S I; Browning M D; Greengard P
Synapsin Ia, synapsin Ib, protein IIIa, and protein IIIb, four related synaptic vesicle-associated phosphoproteins, share regional and cellular localization in rat brain.
Journal of neurochemistry 1988;51(4):1214-20.
1988: Girault J A; Shalaby I A; Rosen N L; Greengard P
Regulation by cAMP and vasoactive intestinal peptide of phosphorylation of specific proteins in striatal cells in culture.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(20):7790-4.
1988: Haycock J W; Greengard P; Browning M D
Cholinergic regulation of protein III phosphorylation in bovine adrenal chromaffin cells.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1988;8(9):3233-9.
1988: Thiel G; Czernik A J; Gorelick F; Nairn A C; Greengard P
Ca2+/calmodulin-dependent protein kinase II: identification of threonine-286 as the autophosphorylation site in the alpha subunit associated with the generation of Ca2+-independent activity.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(17):6337-41.
1988: Gandy S; Czernik A J; Greengard P
Phosphorylation of Alzheimer disease amyloid precursor peptide by protein kinase C and Ca2+/calmodulin-dependent protein kinase II.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(16):6218-21.
1988: Walaas S I; Lustig A; Greengard P; Brugge J S
Widespread distribution of the c-src gene product in nerve cells and axon terminals in the adult rat brain.
Brain research 1988;427(3):215-22.
1988: Hirano A A; Greengard P; Huganir R L
Protein tyrosine kinase activity and its endogenous substrates in rat brain: a subcellular and regional survey.
Journal of neurochemistry 1988;50(5):1447-55.
1988: Audigier S M; Wang J K; Greengard P
Membrane depolarization and carbamoylcholine stimulate phosphatidylinositol turnover in intact nerve terminals.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(8):2859-63.
1988: Aderem A A; Albert K A; Keum M M; Wang J K; Greengard P; Cohn Z A
Stimulus-dependent myristoylation of a major substrate for protein kinase C.
Nature 1988;332(6162):362-4.
1988: Haycock J W; Browning M D; Greengard P
Cholinergic regulation of protein phosphorylation in bovine adrenal chromaffin cells.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(5):1677-81.
1988: Kurihara T; Lewis R M; Eisler J; Greengard P
Cloning of cDNA for DARPP-32, a dopamine- and cyclic AMP-regulated neuronal phosphoprotein.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1988;8(2):508-17.
1988: Valtorta F; Villa A; Jahn R; De Camilli P; Greengard P; Ceccarelli B
Localization of synapsin I at the frog neuromuscular junction.
Neuroscience 1988;24(2):593-603.
1988: Pang D T; Wang J K; Valtorta F; Benfenati F; Greengard P
Protein tyrosine phosphorylation in synaptic vesicles.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(3):762-6.
1988: Nairn A C; Hemmings H C; Walaas S I; Greengard P
DARPP-32 and phosphatase inhibitor-1, two structurally related inhibitors of protein phosphatase-1, are both present in striatonigral neurons.
Journal of neurochemistry 1988;50(1):257-62.
1988: Wang J K; Walaas S I; Greengard P
Protein phosphorylation in nerve terminals: comparison of calcium/calmodulin-dependent and calcium/diacylglycerol-dependent systems.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1988;8(1):281-8.
1988: Li M; McCann J D; Liedtke C M; Nairn A C; Greengard P; Welsh M J
Cyclic AMP-dependent protein kinase opens chloride channels in normal but not cystic fibrosis airway epithelium.
Nature 1988;331(6154):358-60.
1988: Walaas S I; Jahn R; Greengard P
Quantitation of nerve terminal populations: synaptic vesicle-associated proteins as markers for synaptic density in the rat neostriatum.
Synapse (New York, N.Y.) 1988;2(5):516-20.
1988: Greengard P; Browning M D
Studies of the physiological role of specific neuronal phosphoproteins.
Advances in second messenger and phosphoprotein research 1988;21():133-46.
1988: Ouimet C C; Hemmings H C; Greengard P
Dopamine-regulated protein phosphorylation in the basal ganglia.
Advances in experimental medicine and biology 1988;235():1-17.
1988: Hökfelt T; Foster G; Schultzberg M; Meister B; Schalling M; Goldstein M; Hemmings H C; Ouimet C; Greengard P
DARPP-32 as a marker for D-1 dopaminoceptive cells in the rat brain: prenatal development and presence in glial elements (tanycytes) in the basal hypothalamus.
Advances in experimental medicine and biology 1988;235():65-82.
1988: Friedhoff A J; Pickar D; Axelrod J; Creese I; Davis K L; Gallagher D W; Greengard P; Housman D; Maas J W; Richelson E
Neurochemistry and neuropharmacology.
Schizophrenia bulletin 1988;14(3):399-412.
1988: Foster G A; Schultzberg M; Kökfelt T; Goldstein M; Hemmings H C; Ouimet C C; Walaas S I; Greengard P
Ontogeny of the dopamine and cyclic adenosine-3':5'-monophosphate-regulated phosphoprotein (DARPP-32) in the pre- and postnatal mouse central nervous system.
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 1988;6(4):367-86.
1988: Weeks G; Picciotto M; Nairn A C; Walaas S I; Greengard P
Purification and characterization of PCPP-260: a Purkinje cell-enriched cyclic AMP-regulated membrane phosphoprotein of Mr 260,000.
Synapse (New York, N.Y.) 1988;2(1):89-96.
1987: Südhof T C; Lottspeich F; Greengard P; Mehl E; Jahn R
A synaptic vesicle protein with a novel cytoplasmic domain and four transmembrane regions.
Science (New York, N.Y.) 1987;238(4830):1142-4.
1987: Südhof T C; Lottspeich F; Greengard P; Mehl E; Jahn R
The cDNA and derived amino acid sequences for rat and human synaptophysin.
Nucleic acids research 1987;15(22):9607.
1987: Czernik A J; Pang D T; Greengard P
Amino acid sequences surrounding the cAMP-dependent and calcium/calmodulin-dependent phosphorylation sites in rat and bovine synapsin I.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(21):7518-22.
1987: Albert K A; Nairn A C; Greengard P
The 87-kDa protein, a major specific substrate for protein kinase C: purification from bovine brain and characterization.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(20):7046-50.
1987: Miles K; Anthony D T; Rubin L L; Greengard P; Huganir R L
Regulation of nicotinic acetylcholine receptor phosphorylation in rat myotubes by forskolin and cAMP.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(18):6591-5.
1987: Lai Y; Nairn A C; Gorelick F; Greengard P
Ca2+/calmodulin-dependent protein kinase II: identification of autophosphorylation sites responsible for generation of Ca2+/calmodulin-independence.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(16):5710-4.
1987: Thomas N E; Bramson H N; Nairn A C; Greengard P; Fry D C; Mildvan A S; Kaiser E T
Distinguishing among protein kinases by substrate specificities.
Biochemistry 1987;26(14):4471-4.
1987: Hu G Y; Hvalby O; Walaas S I; Albert K A; Skjeflo P; Andersen P; Greengard P
Protein kinase C injection into hippocampal pyramidal cells elicits features of long term potentiation.
Nature 1987;328(6129):426-9.
1987: Foster G A; Schultzberg M; Hökfelt T; Goldstein M; Hemmings H C; Ouimet C C; Walaas S I; Greengard P
Development of a dopamine- and cyclic adenosine 3':5'-monophosphate-regulated phosphoprotein (DARPP-32) in the prenatal rat central nervous system, and its relationship to the arrival of presumptive dopaminergic innervation.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1987;7(7):1994-2018.
1987: Parks T P; Nairn A C; Greengard P; Jamieson J D
The cyclic nucleotide-dependent phosphorylation of aortic smooth muscle membrane proteins.
Archives of biochemistry and biophysics 1987;255(2):361-71.
1987: Nairn A C; Greengard P
Purification and characterization of Ca2+/calmodulin-dependent protein kinase I from bovine brain.
The Journal of biological chemistry 1987;262(15):7273-81.
1987: Romano C; Nichols R A; Greengard P; Greene L A
Synapsin I in PC12 cells. I. Characterization of the phosphoprotein and effect of chronic NGF treatment.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1987;7(5):1294-9.
1987: Romano C; Nichols R A; Greengard P
Synapsin I in PC12 cells. II. Evidence for regulation by NGF of phosphorylation at a novel site.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1987;7(5):1300-6.
1987: Bähler M; Greengard P
Synapsin I bundles F-actin in a phosphorylation-dependent manner.
Nature 1987;326(6114):704-7.
1987: Browning M D; Huang C K; Greengard P
Similarities between protein IIIa and protein IIIb, two prominent synaptic vesicle-associated phosphoproteins.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1987;7(3):847-53.
1987: Nichols R A; Haycock J W; Wang J K; Greengard P
Phorbol ester enhancement of neurotransmitter release from rat brain synaptosomes.
Journal of neurochemistry 1987;48(2):615-21.
1987: Hammond C; Paupardin-Tritsch D; Nairn A C; Greengard P; Gerschenfeld H M
Cholecystokinin induces a decrease in Ca2+ current in snail neurons that appears to be mediated by protein kinase C.
Nature 1987;325(6107):809-11.
1987: Greengard P
Neuronal phosphoproteins. Mediators of signal transduction.
Molecular neurobiology 1987;1(1-2):81-119.
1987: Greengard P; Browning M D; McGuinness T L; Llinas R
Synapsin I, a phosphoprotein associated with synaptic vesicles: possible role in regulation of neurotransmitter release.
Advances in experimental medicine and biology 1987;221():135-53.
1986: Navone F; Jahn R; Di Gioia G; Stukenbrok H; Greengard P; De Camilli P
Protein p38: an integral membrane protein specific for small vesicles of neurons and neuroendocrine cells.
The Journal of cell biology 1986;103(6 Pt 1):2511-27.
1986: De Camilli P; Greengard P
Synapsin I: a synaptic vesicle-associated neuronal phosphoprotein.
Biochemical pharmacology 1986;35(24):4349-57.
1986: Stone R A; Laties A M; Hemmings H C; Ouimet C C; Greengard P
DARPP-32 in the ciliary epithelium of the eye: a neurotransmitter-regulated phosphoprotein of brain localizes to secretory cells.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 1986;34(11):1465-8.
1986: Valtorta F; Schiebler W; Jahn R; Ceccarelli B; Greengard P
A solid-phase assay for the phosphorylation of proteins blotted on nitrocellulose membrane filters.
Analytical biochemistry 1986;158(1):130-7.
1986: Paupardin-Tritsch D; Hammond C; Gerschenfeld H M; Nairn A C; Greengard P
cGMP-dependent protein kinase enhances Ca2+ current and potentiates the serotonin-induced Ca2+ current increase in snail neurones.
Nature 1986;323(6091):812-4.
1986: Mackie K; Lai Y; Nairn A C; Greengard P; Pitt B R; Lazo J S
Protein phosphorylation in cultured endothelial cells.
Journal of cellular physiology 1986;128(3):367-74.
1986: Schiebler W; Jahn R; Doucet J P; Rothlein J; Greengard P
Characterization of synapsin I binding to small synaptic vesicles.
The Journal of biological chemistry 1986;261(18):8383-90.
1986: Lai Y; Nairn A C; Greengard P
Autophosphorylation reversibly regulates the Ca2+/calmodulin-dependence of Ca2+/calmodulin-dependent protein kinase II.
Proceedings of the National Academy of Sciences of the United States of America 1986;83(12):4253-7.
1986: Huganir R L; Delcour A H; Greengard P; Hess G P
Phosphorylation of the nicotinic acetylcholine receptor regulates its rate of desensitization.
Nature 1986;321(6072):774-6.
1986: Hemmings H C; Greengard P
DARPP-32, a dopamine- and adenosine 3':5'-monophosphate-regulated phosphoprotein: regional, tissue, and phylogenetic distribution.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1986;6(5):1469-81.
1986: Albert K A; Walaas S I; Wang J K; Greengard P
Widespread occurrence of "87 kDa," a major specific substrate for protein kinase C.
Proceedings of the National Academy of Sciences of the United States of America 1986;83(9):2822-6.
1986: Saez J C; Spray D C; Nairn A C; Hertzberg E; Greengard P; Bennett M V
cAMP increases junctional conductance and stimulates phosphorylation of the 27-kDa principal gap junction polypeptide.
Proceedings of the National Academy of Sciences of the United States of America 1986;83(8):2473-7.
1986: Walaas S I; Nairn A C; Greengard P
PCPP-260, a Purkinje cell-specific cyclic AMP-regulated membrane phosphoprotein of Mr 260,000.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1986;6(4):954-61.
1986: Williams K R; Hemmings H C; LoPresti M B; Konigsberg W H; Greengard P
DARPP-32, a dopamine- and cyclic AMP-regulated neuronal phosphoprotein. Primary structure and homology with protein phosphatase inhibitor-1.
The Journal of biological chemistry 1986;261(4):1890-903.
1986: Hemmings H C; Greengard P
DARPP-32, a dopamine-regulated phosphoprotein.
Progress in brain research 1986;69():149-59.
1986: Nestler E J; Greengard P
Synapsin I: a review of its distribution and biological regulation.
Progress in brain research 1986;69():323-39.
1986: Hemmings H C; Nairn A C; Greengard P
Protein kinases and phosphoproteins in the nervous system.
Research publications - Association for Research in Nervous and Mental Disease 1986;64():47-69.
1985: DeRiemer S A; Greengard P; Kaczmarek L K
Calcium/phosphatidylserine/diacylglycerol-dependent protein phosphorylation in the Aplysia nervous system.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1985;5(10):2672-6.
1985: Goelz S E; Nestler E J; Greengard P
Phylogenetic survey of proteins related to synapsin I and biochemical analysis of four such proteins from fish brain.
Journal of neurochemistry 1985;45(1):63-72.
1985: Browning M D; Huganir R; Greengard P
Protein phosphorylation and neuronal function.
Journal of neurochemistry 1985;45(1):11-23.
1985: Treiman M; Greengard P
D-1 and D-2 dopaminergic receptors regulate protein phosphorylation in the rat neurohypophysis.
Neuroscience 1985;15(3):713-22.
1985: Jahn R; Schiebler W; Ouimet C; Greengard P
A 38,000-dalton membrane protein (p38) present in synaptic vesicles.
Proceedings of the National Academy of Sciences of the United States of America 1985;82(12):4137-41.
1985: Llinás R; McGuinness T L; Leonard C S; Sugimori M; Greengard P
Intraterminal injection of synapsin I or calcium/calmodulin-dependent protein kinase II alters neurotransmitter release at the squid giant synapse.
Proceedings of the National Academy of Sciences of the United States of America 1985;82(9):3035-9.
1985: McGuinness T L; Lai Y; Greengard P
Ca2+/calmodulin-dependent protein kinase II. Isozymic forms from rat forebrain and cerebellum.
The Journal of biological chemistry 1985;260(3):1696-704.
1985: Mobley P; Greengard P
Evidence for widespread effects of noradrenaline on axon terminals in the rat frontal cortex.
Proceedings of the National Academy of Sciences of the United States of America 1985;82(3):945-7.
1985: DeRiemer S A; Strong J A; Albert K A; Greengard P; Kaczmarek L K
Enhancement of calcium current in Aplysia neurones by phorbol ester and protein kinase C.
Nature 1985;313(6000):313-6.
1985: Nairn A C; Hemmings H C; Greengard P
Protein kinases in the brain.
Annual review of biochemistry 1985;54():931-76.
1984: Hemmings H C; Nairn A C; Greengard P
DARPP-32, a dopamine- and adenosine 3':5'-monophosphate-regulated neuronal phosphoprotein. II. Comparison of the kinetics of phosphorylation of DARPP-32 and phosphatase inhibitor 1.
The Journal of biological chemistry 1984;259(23):14491-7.
1984: Hemmings H C; Williams K R; Konigsberg W H; Greengard P
DARPP-32, a dopamine- and adenosine 3':5'-monophosphate-regulated neuronal phosphoprotein. I. Amino acid sequence around the phosphorylated threonine.
The Journal of biological chemistry 1984;259(23):14486-90.
1984: Navone F; Greengard P; De Camilli P
Synapsin I in nerve terminals: selective association with small synaptic vesicles.
Science (New York, N.Y.) 1984;226(4679):1209-11.
1984: Albert K A; Helmer-Matyjek E; Nairn A C; Müller T H; Haycock J W; Greene L A; Goldstein M; Greengard P
Calcium/phospholipid-dependent protein kinase (protein kinase C) phosphorylates and activates tyrosine hydroxylase.
Proceedings of the National Academy of Sciences of the United States of America 1984;81(24):7713-7.
1984: Huganir R L; Miles K; Greengard P
Phosphorylation of the nicotinic acetylcholine receptor by an endogenous tyrosine-specific protein kinase.
Proceedings of the National Academy of Sciences of the United States of America 1984;81(22):6968-72.
1984: Perdahl E; Wu W C; Browning M D; Winblad B; Greengard P
Protein III, a neuron-specific phosphoprotein: variant forms found in human brain.
Neurobehavioral toxicology and teratology 1984;6(6):425-31.
1984: Detre J A; Nairn A C; Aswad D W; Greengard P
Localization in mammalian brain of G-substrate, a specific substrate for guanosine 3',5'-cyclic monophosphate-dependent protein kinase.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1984;4(11):2843-9.
1984: Levitt P; Rakic P; De Camilli P; Greengard P
Emergence of cyclic guanosine 3':5'-monophosphate-dependent protein kinase immunoreactivity in developing rhesus monkey cerebellum: correlative immunocytochemical and electron microscopic analysis.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1984;4(10):2553-64.
1984: Ouimet C C; McGuinness T L; Greengard P
Immunocytochemical localization of calcium/calmodulin-dependent protein kinase II in rat brain.
Proceedings of the National Academy of Sciences of the United States of America 1984;81(17):5604-8.
1984: Nestler E J; Walaas S I; Greengard P
Neuronal phosphoproteins: physiological and clinical implications.
Science (New York, N.Y.) 1984;225(4668):1357-64.
1984: Hemmings H C; Greengard P; Tung H Y; Cohen P
DARPP-32, a dopamine-regulated neuronal phosphoprotein, is a potent inhibitor of protein phosphatase-1.
Nature 1984;310(5977):503-5.
1984: King M M; Huang C Y; Chock P B; Nairn A C; Hemmings H C; Chan K F; Greengard P
Mammalian brain phosphoproteins as substrates for calcineurin.
The Journal of biological chemistry 1984;259(13):8080-3.
1984: DeRiemer S A; Kaczmarek L K; Lai Y; McGuinness T L; Greengard P
Calcium/calmodulin-dependent protein phosphorylation in the nervous system of Aplysia.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1984;4(6):1618-25.
1984: Albert K A; Wu W C; Nairn A C; Greengard P
Inhibition by calmodulin of calcium/phospholipid-dependent protein phosphorylation.
Proceedings of the National Academy of Sciences of the United States of America 1984;81(12):3622-5.
1984: De Camilli P; Miller P E; Levitt P; Walter U; Greengard P
Anatomy of cerebellar Purkinje cells in the rat determined by a specific immunohistochemical marker.
Neuroscience 1984;11(4):761-817.
1984: Jahn R; Schiebler W; Greengard P
A quantitative dot-immunobinding assay for proteins using nitrocellulose membrane filters.
Proceedings of the National Academy of Sciences of the United States of America 1984;81(6):1684-7.
1984: Kelly P T; McGuinness T L; Greengard P
Evidence that the major postsynaptic density protein is a component of a Ca2+/calmodulin-dependent protein kinase.
Proceedings of the National Academy of Sciences of the United States of America 1984;81(3):945-9.
1984: Hemmings H C; Nairn A C; Aswad D W; Greengard P
DARPP-32, a dopamine- and adenosine 3':5'-monophosphate-regulated phosphoprotein enriched in dopamine-innervated brain regions. II. Purification and characterization of the phosphoprotein from bovine caudate nucleus.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1984;4(1):99-110.
1984: Walaas S I; Greengard P
DARPP-32, a dopamine- and adenosine 3':5'-monophosphate-regulated phosphoprotein enriched in dopamine-innervated brain regions. I. Regional and cellular distribution in the rat brain.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1984;4(1):84-98.
1984: Ouimet C C; Miller P E; Hemmings H C; Walaas S I; Greengard P
DARPP-32, a dopamine- and adenosine 3':5'-monophosphate-regulated phosphoprotein enriched in dopamine-innervated brain regions. III. Immunocytochemical localization.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1984;4(1):111-24.
1984: Palfrey H C; Lai Y; Greengard P
Calmodulin-dependent protein kinase from avian erythrocytes.
Progress in clinical and biological research 1984;165():291-308.
1984: Perdahl E; Adolfsson R; Alafuzoff I; Albert K A; Nestler E J; Greengard P; Winblad B
Synapsin I (protein I) in different brain regions in senile dementia of Alzheimer type and in multi-infarct dementia.
Journal of neural transmission 1984;60(2):133-41.
1984: Nestler E J; Greengard P
Neuron-specific phosphoproteins in mammalian brain.
Advances in cyclic nucleotide and protein phosphorylation research 1984;17():483-8.
1983: McGuinness T L; Lai Y; Greengard P; Woodgett J R; Cohen P
A multifunctional calmodulin-dependent protein kinase. Similarities between skeletal muscle glycogen synthase kinase and a brain synapsin I kinase.
FEBS letters 1983;163(2):329-34.
1983: Nairn A C; Greengard P
Cyclic GMP-dependent protein phosphorylation in mammalian brain.
Federation proceedings 1983;42(14):3107-13.
1983: Nestler E J; Greengard P
Protein phosphorylation in the brain.
Nature 1983;305(5935):583-8.
1983: Palfrey H C; Rothlein J E; Greengard P
Calmodulin-dependent protein kinase and associated substrates in Torpedo electric organ.
The Journal of biological chemistry 1983;258(15):9496-503.
1983: Tank D W; Huganir R L; Greengard P; Webb W W
Patch-recorded single-channel currents of the purified and reconstituted Torpedo acetylcholine receptor.
Proceedings of the National Academy of Sciences of the United States of America 1983;80(16):5129-33.
1983: Huttner W B; Schiebler W; Greengard P; De Camilli P
Synapsin I (protein I), a nerve terminal-specific phosphoprotein. III. Its association with synaptic vesicles studied in a highly purified synaptic vesicle preparation.
The Journal of cell biology 1983;96(5):1374-88.
1983: De Camilli P; Harris S M; Huttner W B; Greengard P
Synapsin I (Protein I), a nerve terminal-specific phosphoprotein. II. Its specific association with synaptic vesicles demonstrated by immunocytochemistry in agarose-embedded synaptosomes.
The Journal of cell biology 1983;96(5):1355-73.
1983: De Camilli P; Cameron R; Greengard P
Synapsin I (protein I), a nerve terminal-specific phosphoprotein. I. Its general distribution in synapses of the central and peripheral nervous system demonstrated by immunofluorescence in frozen and plastic sections.
The Journal of cell biology 1983;96(5):1337-54.
1983: Kennedy M B; McGuinness T; Greengard P
A calcium/calmodulin-dependent protein kinase from mammalian brain that phosphorylates Synapsin I: partial purification and characterization.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1983;3(4):818-31.
1983: Huganir R L; Greengard P
cAMP-dependent protein kinase phosphorylates the nicotinic acetylcholine receptor.
Proceedings of the National Academy of Sciences of the United States of America 1983;80(4):1130-4.
1983: Walaas S I; Nairn A C; Greengard P
Regional distribution of calcium- and cyclic adenosine 3':5'-monophosphate-regulated protein phosphorylation systems in mammalian brain. II. Soluble systems.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1983;3(2):302-11.
1983: Walaas S I; Nairn A C; Greengard P
Regional distribution of calcium- and cyclic adenosine 3':5'-monophosphate-regulated protein phosphorylation systems in mammalian brain. I. Particulate systems.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1983;3(2):291-301.
1983: Dolphin A C; Detre J A; Schlichter D J; Nairn A C; Yeh H H; Woodward D J; Greengard P
Cyclic nucleotide-dependent protein kinases and some major substrates in the rat cerebellum after neonatal X-irradiation.
Journal of neurochemistry 1983;40(2):577-81.
1983: Walaas S I; Aswad D W; Greengard P
A dopamine- and cyclic AMP-regulated phosphoprotein enriched in dopamine-innervated brain regions.
Nature 1983;301(5895):69-71.
1983: Lewis R M; Wallace W C; Kanazir S D; Greengard P
Expression of cell-type-specific neuronal phosphoproteins.
Cold Spring Harbor symposia on quantitative biology 1983;48 Pt 1():347-54.
1983: DeGennaro L J; Kanazir S D; Wallace W C; Lewis R M; Greengard P
Neuron-specific phosphoproteins as models for neuronal gene expression.
Cold Spring Harbor symposia on quantitative biology 1983;48 Pt 1():337-45.
1983: Walter U; Greengard P
Photoaffinity labeling of the regulatory subunit of cAMP-dependent protein kinase.
Methods in enzymology 1983;99():154-62.
1982: Castellucci V F; Nairn A; Greengard P; Schwartz J H; Kandel E R
Inhibitor of adenosine 3':5'-monophosphate-dependent protein kinase blocks presynaptic facilitation in Aplysia.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1982;2(12):1673-81.
1982: Tsou K; Greengard P
Regulation of phosphorylation of proteins I, IIIa, and IIIb in rat neurohypophysis in vitro by electrical stimulation and by neuroactive agents.
Proceedings of the National Academy of Sciences of the United States of America 1982;79(19):6075-9.
1982: Nairn A C; Detre J A; Casnellie J E; Greengard P
Serum antibodies that distinguish between the phospho- and dephospho-forms of a phosphoprotein.
Nature 1982;299(5885):734-6.
1982: Wu W C; Walaas S I; Nairn A C; Greengard P
Calcium/phospholipid regulates phosphorylation of a Mr "87k" substrate protein in brain synaptosomes.
Proceedings of the National Academy of Sciences of the United States of America 1982;79(17):5249-53.
1982: Nestler E J; Greengard P
Distribution of protein I and regulation of its state of phosphorylation in the rabbit superior cervical ganglion.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1982;2(8):1011-23.
1982: Nestler E J; Zata M; Greengard P
A diurnal rhythm in pineal protein 1 content mediated by beta-adrenergic neurotransmission.
Science (New York, N.Y.) 1982;217(4557):357-9.
1982: Palfrey H C; Schiebler W; Greengard P
A major calmodulin-binding protein common to various vertebrate tissues.
Proceedings of the National Academy of Sciences of the United States of America 1982;79(12):3780-4.
1982: Huang C K; Browning M D; Greengard P
Purification and characterization of protein IIIb, a mammalian brain phosphoprotein.
The Journal of biological chemistry 1982;257(11):6524-8.
1982: Fried G; Nestler E J; De Camilli P; Stjärne L; Olson L; Lundberg J M; Hökfelt T; Ouimet C C; Greengard P
Cellular and subcellular localization of protein I in the peripheral nervous system.
Proceedings of the National Academy of Sciences of the United States of America 1982;79(8):2717-21.
1982: Nestler E J; Greengard P
Nerve impulses increase the phosphorylation state of protein I in rabbit superior cervical ganglion.
Nature 1982;296(5856):452-4.
1982: Robinson N L; Cox P M; Greengard P
Glutamate regulates adenylate cyclase and guanylate cyclase activities in an isolated membrane preparation from insect muscle.
Nature 1982;296(5855):354-6.
1981: Sieghart W; Theoharides T C; Douglas W W; Greengard P
Phosphorylation of a single mast cell protein in response to drugs that inhibit secretion.
Biochemical pharmacology 1981;30(19):2737-8.
1981: Theoharides T C; Sieghart W; Greengard P; Douglas W W
Somatostatin-induced phosphorylation of mast cell proteins.
Biochemical pharmacology 1981;30(19):2735-6.
1981: Nestler E J; Rainbow T C; McEwen B S; Greengard P
Corticosterone increases the amount of protein 1, a neuron-specific phosphoprotein, in rat hippocampus.
Science (New York, N.Y.) 1981;212(4499):1162-4.
1981: Dolphin A C; Greengard P
Presence of protein I, a phosphoprotein associated with synaptic vesicles, in cerebellar granule cells.
Journal of neurochemistry 1981;36(5):1627-31.
1981: Goelz S E; Nestler E J; Chehrazi B; Greengard P
Distribution of protein I in mammalian brain as determined by a detergent-based radioimmunoassay.
Proceedings of the National Academy of Sciences of the United States of America 1981;78(4):2130-4.
1981: Aitken A; Bilham T; Cohen P; Aswad D; Greengard P
A specific substrate from rabbit cerebellum for guanosine-3':5'-monophosphate-dependent protein kinase. III. Amino acid sequences at the two phosphorylation sites.
The Journal of biological chemistry 1981;256(7):3501-6.
1981: Aswad D W; Greengard P
A specific substrate from rabbit cerebellum for guanosine 3':5'-monophosphate-dependent protein kinase. II. Kinetic studies on its phosphorylation by guanosine 3':5'-monophosphate-dependent and adenosine 3':5'-monophosphate-dependent protein kinases.
The Journal of biological chemistry 1981;256(7):3494-500.
1981: Aswad D W; Greengard P
A specific substrate from rabbit cerebellum for guanosine 3':5'-monophosphate-dependent protein kinase. I. Purification and characterization.
The Journal of biological chemistry 1981;256(7):3487-93.
1981: Liu A Y; Walter U; Greengard P
Steroid hormones may regulate autophosphorylation of adenosine-3',5'-monophosphate-dependent protein kinase in target tissues.
European journal of biochemistry / FEBS 1981;114(3):539-48.
1981: Kennedy M B; Greengard P
Two calcium/calmodulin-dependent protein kinases, which are highly concentrated in brain, phosphorylate protein I at distinct sites.
Proceedings of the National Academy of Sciences of the United States of America 1981;78(2):1293-7.
1981: Huttner W B; DeGennaro L J; Greengard P
Differential phosphorylation of multiple sites in purified protein I by cyclic AMP-dependent and calcium-dependent protein kinases.
The Journal of biological chemistry 1981;256(3):1482-8.
1981: Dolphin A C; Greengard P
Neurotransmitter- and neuromodulator-dependent alterations in phosphorylation of protein I in slices of rat facial nucleus.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1981;1(2):192-203.
1981: Lohmann S M; Walter U; Miller P E; Greengard P; De Camilli P
Immunohistochemical localization of cyclic GMP-dependent protein kinase in mammalian brain.
Proceedings of the National Academy of Sciences of the United States of America 1981;78(1):653-7.
1981: Dolphin A C; Greengard P
Serotonin stimulates phosphorylation of protein I in the facial motor nucleus of rat brain.
Nature 1981;289(5793):76-9.
1981: Palfrey H C; Greengard P
Hormone-sensitive ion transport systems in erythrocytes as models for epithelial ion pathways.
Annals of the New York Academy of Sciences 1981;372():291-308.
1981: Walter U; Greengard P
Cyclic AMP-dependent and cyclic GMP-dependent protein kinases of nervous tissue.
Current topics in cellular regulation 1981;19():219-56.
1980: Kaczmarek L K; Jennings K R; Strumwasser F; Nairn A C; Walter U; Wilson F D; Greengard P
Microinjection of catalytic subunit of cyclic AMP-dependent protein kinase enhances calcium action potentials of bag cell neurons in cell culture.
Proceedings of the National Academy of Sciences of the United States of America 1980;77(12):7487-91.
1980: Palfrey H C; Alper S L; Greengard P
Protein phosphorylation and the regulation of cation cotransport.
The Journal of experimental biology 1980;89():103-15.
1980: Yamazaki A; Sen I; Bitensky M W; Casnellie J E; Greengard P
Cyclic GMP-specific, high affinity, noncatalytic binding sites on light-activated phosphodiesterase.
The Journal of biological chemistry 1980;255(23):11619-24.
1980: Nestler E J; Greengard P
Dopamine and depolarizing agents regulate the state of phosphorylation of protein I in the mammalian superior cervical sympathetic ganglion.
Proceedings of the National Academy of Sciences of the United States of America 1980;77(12):7479-83.
1980: Castellucci V F; Kandel E R; Schwartz J H; Wilson F D; Nairn A C; Greengard P
Intracellular injection of t he catalytic subunit of cyclic AMP-dependent protein kinase simulates facilitation of transmitter release underlying behavioral sensitization in Aplysia.
Proceedings of the National Academy of Sciences of the United States of America 1980;77(12):7492-6.
1980: Alper S L; Palfrey H C; DeRiemer S A; Greengard P
Hormonal control of protein phosphorylation in turkey erythrocytes. Phosphorylation by cAMP-dependent and Ca2+-dependent protein kinases of distinct sites in goblin, a high molecular weight protein of the plasma membrane.
The Journal of biological chemistry 1980;255(22):11029-39.
1980: Lohmann S M; Walter U; Greengard P
Identification of endogenous substrate proteins for cAMP-dependent protein kinase in bovine brain.
The Journal of biological chemistry 1980;255(20):9985-92.
1980: Schlichter D J; Detre J A; Aswad D W; Chehrazi B; Greengard P
Localization of cyclic GMP-dependent protein kinase and substrate in mammalian cerebellum.
Proceedings of the National Academy of Sciences of the United States of America 1980;77(9):5537-41.
1980: Rudolph S A; Greengard P
Effects of catecholamines and prostaglandin E1 on cyclic AMP, cation fluxes, and protein phosphorylation in the frog erythrocyte.
The Journal of biological chemistry 1980;255(18):8534-40.
1980: Alper S L; Beam K G; Greengard P
Hormonal control of Na+-K+ co-transport in turkey erythrocytes. Multiple site phosphorylation of goblin, a high molecular weight protein of the plasma membrane.
The Journal of biological chemistry 1980;255(10):4864-71.
1980: Ives H E; Casnellie J E; Greengard P; Jamieson J D
Subcellular localization of cyclic GMP-dependent protein kinase and its substrates in vascular smooth muscle.
The Journal of biological chemistry 1980;255(8):3777-85.
1980: Casnellie J E; Ives H E; Jamieson J D; Greengard P
Cyclic GMP-dependent protein phosphorylation in intact medial tissue and isolated cells from vascular smooth muscle.
The Journal of biological chemistry 1980;255(8):3770-6.
1980: Walter U; Miller P; Wilson F; Menkes D; Greengard P
Immunological distinction between guanosine 3':5'-monophosphate-dependent and adenosine 3':5'-monophosphate-dependent protein kinases.
The Journal of biological chemistry 1980;255(8):3757-62.
1980: Sieghart W; Schulman H; Greengard P
Neuronal localization of Ca2+-dependent protein phosphorylation in brain.
Journal of neurochemistry 1980;34(3):548-53.
1980: Palfrey H C; Feit P W; Greengard P
cAMP-stimulated cation cotransport in avian erythrocytes: inhibition by "loop" diuretics.
The American journal of physiology 1980;238(3):C139-48.
1980: Theoharides T C; Sieghart W; Greengard P; Douglas W W
Antiallergic drug cromolyn may inhibit histamine secretion by regulating phosphorylation of a mast cell protein.
Science (New York, N.Y.) 1980;207(4426):80-2.
1980: Palfrey H C; Greengard P; Feit P W
Specific inhibition by "loop" diuretics of an anion-dependent Na+ + K+ cotransport system in avian erythrocytes.
Annals of the New York Academy of Sciences 1980;341():134-8.
1980: Dolphin A C; Goelz S E; Greengard P
Neuronal protein phosphorylation: recent studies concerning protein I, a synapse-specific phosphoprotein.
Pharmacology, biochemistry, and behavior 1980;13 Suppl 1():169-74.
1979: Krieger N R; Bunney B S; Greengard P
Localization of dopamine-sensitive adenylate cyclase activity within laminae of the rat prefrontal cortex.
Brain research 1979;179(1):171-5.
1979: Walter U; Lohmann S M; Sieghart W; Greengard P
Identification of the cyclic AMP-dependent protein kinase responsible for endogenous phosphorylation of substrate proteins in synaptic membrane fraction from rat brain.
The Journal of biological chemistry 1979;254(23):12235-9.
1979: Bloom F E; Ueda T; Battenberg E; Greengard P
Immunocytochemical localization, in synapses, of protein I, an endogenous substrate for protein kinases in mammalian brain.
Proceedings of the National Academy of Sciences of the United States of America 1979;76(11):5982-6.
1979: De Camilli P; Ueda T; Bloom F E; Battenberg E; Greengard P
Widespread distribution of protein I in the central and peripheral nervous systems.
Proceedings of the National Academy of Sciences of the United States of America 1979;76(11):5977-81.
1979: Ueda T; Greengard P; Berzins K; Cohen R S; Blomberg F; Grab D J; Siekevitz P
Subcellular distribution in cerebral cortex of two proteins phosphorylated by a cAMP-dependent protein kinase.
The Journal of cell biology 1979;83(2 Pt 1):308-19.
1979: Rudolph S A; Hegstrand L R; Greengard P; Malawista S E
The interaction of colchicine with hormone-sensitive adenylate cyclase in human leukocytes.
Molecular pharmacology 1979;16(3):805-12.
1979: Beam K G; Alper S L; Palade G E; Greengard P
Hormonally regulated phosphoprotein of turkey erythrocytes: localization to plasma membrane.
The Journal of cell biology 1979;83(1):1-15.
1979: Huttner W B; Greengard P
Multiple phosphorylation sites in protein I and their differential regulation by cyclic AMP and calcium.
Proceedings of the National Academy of Sciences of the United States of America 1979;76(10):5402-6.
1979: Strömbom U; Forn J; Dolphin A C; Greengard P
Regulation of the state of phosphorylation of specific neuronal proteins in mouse brain by in vivo administration of anesthetic and convulsant agents.
Proceedings of the National Academy of Sciences of the United States of America 1979;76(9):4687-90.
1979: Walter U; Costa M R; Breakefield X O; Greengard P
Presence of free cyclic AMP receptor protein and regulation of its level by cyclic AMP in neuroblastoma-glioma hybrid cells.
Proceedings of the National Academy of Sciences of the United States of America 1979;76(7):3251-5.
1979: Greengard P
Cyclic nucleotides, phosphorylated proteins, and the nervous system.
Federation proceedings 1979;38(8):2208-17.
1979: Sieghart W; Forn J; Greengard P
Ca2+ and cyclic AMP regulate phosphorylation of same two membrane-associated proteins specific to nerve tissue.
Proceedings of the National Academy of Sciences of the United States of America 1979;76(5):2475-9.
1979: Kanof P D; Greengard P
Pharmacological properties of histamine-sensitive adenylate cyclase from guinea pig cardiac ventricular muscle.
Molecular pharmacology 1979;15(3):445-61.
1979: Kanof P D; Greengard P
Pharmacological properties of histamine-sensitive adenylate cyclase from mammalian brain.
The Journal of pharmacology and experimental therapeutics 1979;209(1):87-96.
1979: Sieghart W; Strombom U; Walter U; Greengard P
Drug interactions with cyclic nucleotide and protein phosphorylation systems.
Progress in clinical and biological research 1979;27():123-34.
1979: Greengard P
Intracellular signals in the brain.
Harvey lectures 1979;75():277-331.
1978: Lohmann S M; Walter U; Greengard P
Protein kinases in developing rat brain.
Journal of cyclic nucleotide research 1978;4(6):445-52.
1978: Walter U; Greengard P
Quantitative labeling of the regulatory subunit of type II cAMP-dependent protein kinase from bovine heart by a photoaffinity analog.
Journal of cyclic nucleotide research 1978;4(6):437-44.
1978: Study R E; Breakefield X O; Bartfai T; Greengard P
Voltage-sensitive calcium channels regulate guanosine 3',5'-cyclic monophosphate levels in neuroblastoma cells.
Proceedings of the National Academy of Sciences of the United States of America 1978;75(12):6295-9.
1978: Study R E; Greengard P
Regulation by histamine of cyclic nucleotide levels in sympathetic ganglia.
The Journal of pharmacology and experimental therapeutics 1978;207(3):767-78.
1978: Schulman H; Greengard P
Ca2+-dependent protein phosphorylation system in membranes from various tissues, and its activation by "calcium-dependent regulator".
Proceedings of the National Academy of Sciences of the United States of America 1978;75(11):5432-6.
1978: Sieghart W; Forn J; Schwarcz R; Coyle J T; Greengard P
Neuronal localization of specific brain phosphoproteins.
Brain research 1978;156(2):345-50.
1978: Nestler E J; Beam K G; Greengard P
Nicotinic cholinergic stimulation increases cyclic GMP levels in vertebrate skeletal muscle.
Nature 1978;275(5679):451-3.
1978: Forn J; Greengard P
Depolarizing agents and cyclic nucleotides regulate the phosphorylation of specific neuronal proteins in rat cerebral cortex slices.
Proceedings of the National Academy of Sciences of the United States of America 1978;75(10):5195-9.
1978: Bartfai T; Breakefield X O; Greengard P
Regulation of synthesis of guanosine 3':5'-cyclic monophosphate in neuroblastoma cells.
The Biochemical journal 1978;176(1):119-27.
1978: Sieghart W; Theoharides T C; Alper S L; Douglas W W; Greengard P
Calcium-dependent protein phosphorylation during secretion by exocytosis in the mast cell.
Nature 1978;275(5678):329-31.
1978: Walter U; Kanof P; Schulman H; Greengard P
Adenosine 3':5'-monophosphate receptor proteins in mammalian brain.
The Journal of biological chemistry 1978;253(17):6275-80.
1978: Lohmann S M; Ueda T; Greengard P
Ontogeny of synaptic phosphoproteins in brain.
Proceedings of the National Academy of Sciences of the United States of America 1978;75(8):4037-41.
1978: Casnellie J E; Schlichter D J; Walter U; Greengard P
Photoaffinity labeling of a guanosine 3':5'-monophosphate-dependent protein kinase from vascular smooth muscle.
The Journal of biological chemistry 1978;253(13):4771-6.
1978: Schlichter D J; Casnellie J E; Greengard P
An endogenous substrate for cGMP-dependent protein kinase in mammalian cerebellum.
Nature 1978;273(5657):61-2.
1978: Kanof P D; Greengard P
Brain histamine receptors as targets for antidepressant drugs.
Nature 1978;272(5651):329-33.
1978: Schulman H; Greengard P
Stimulation of brain membrane protein phosphorylation by calcium and an endogenous heat-stable protein.
Nature 1978;271(5644):478-9.
1978: Greengard P
Phosphorylated proteins as physiological effectors.
Science (New York, N.Y.) 1978;199(4325):146-52.
1977: Rudolph S A; Schafer D E; Greengard P
Effects of cholera enterotoxin on catecholamine-stimulated changes in cation fluxes, cell volume, and cyclic AMP levels in the turkey erythrocyte.
The Journal of biological chemistry 1977;252(20):7132-9.
1977: Walter U; Uno I; Liu A Y; Greengard P
Study of autophosphorylation of isoenzymes of cyclic AMP-dependent protein kinases.
The Journal of biological chemistry 1977;252(19):6588-90.
1977: Uno I; Ueda T; Greengard P
Enzyme systems involved in phosphorylation and dephosphorylation of two endogenous phosphoproteins in neuronal membranes.
Archives of biochemistry and biophysics 1977;183(2):480-9.
1977: Walter U; Uno I; Liu A Y; Greengard P
Identification, characterization, and quantitative measurement of cyclic AMP receptor proteins in cytosol of various tissues using a photoaffinity ligand.
The Journal of biological chemistry 1977;252(18):6494-500.
1977: Rudolph S A; Greengard P; Malawista S E
Effects of colchicine on cyclic AMP levels in human leukocytes.
Proceedings of the National Academy of Sciences of the United States of America 1977;74(8):3404-8.
1977: Krieger N R; Kauer J S; Shepherd G M; Greengard P
Dopamine-sensitive adenylate cyclase within laminae of the olfactory tubercle.
Brain research 1977;131(2):303-12.
1977: Nathanson J A; Greengard P
"Second messengers" in the brain.
Scientific American 1977;237(2):109-19.
1977: Ueda T; Greengard P
Adenosine 3':5'-monophosphate-regulated phosphoprotein system of neuronal membranes. I. Solubilization, purification, and some properties of an endogenous phosphoprotein.
The Journal of biological chemistry 1977;252(14):5155-63.
1977: Kanof P D; Hegstrand L R; Greengard P
Biochemical characterization of histamine-sensitive adenylate cyclase in mammalian brain.
Archives of biochemistry and biophysics 1977;182(1):321-34.
1977: Uno I; Ueda T; Greengard P
Adenosine 3':5'-monophosphate-regulated phosphoprotein system of neuronal membranes. II. Solubilization, purification, and some properties of an endogenous adenosine 3':5'-monophosphate-dependent protein kinase.
The Journal of biological chemistry 1977;252(14):5164-74.
1977: Beam K G; Nestler E J; Greengard P
Increased cyclic GMP levels associated with contraction in muscle fibres of the giant barnacle.
Nature 1977;267(5611):534-6.
1977: Krueger B K; Forn J; Greengard P
Depolarization-induced phosphorylation of specific proteins, mediated by calcium ion influx, in rat brain synaptosomes.
The Journal of biological chemistry 1977;252(8):2764-73.
1976: Forn J; Greengard P
Regulation by lipolytic and antillipolytic compounds of the phosphorylation of specific proteins in isolated intact fat cells.
Archives of biochemistry and biophysics 1976;176(2):721-33.
1976: Krueger B K; Forn J; Walters J R; Roth R H; Greengard P
Stimulation by dopamine of adenosine cyclic 3',5'-monophosphate formation in rat caudate nucleus: effect of lesions of the nigro-neostriatal pathway.
Molecular pharmacology 1976;12(4):639-48.
1976: Greengard P
Possible role for cyclic nucleotides and phosphorylated membrane proteins in postsynaptic actions of neurotransmitters.
Nature 1976;260(5547):101-8.
1976: Hegstrand L R; Kanof P D; Greengard P
Histamine-sensitive adenylate cyclase in mammalian brain.
Nature 1976;260(5547):163-5.
1976: Liu A Y; Greengard P
Regulation by steroid hormones of phosphorylation of specific protein common to several target organs.
Proceedings of the National Academy of Sciences of the United States of America 1976;73(2):568-72.
1976: Beam K G; Greengard P
Cyclic nucleotides, protein phosphorylation and synaptic function.
Cold Spring Harbor symposia on quantitative biology 1976;40():157-68.
1975: Krueger B K; Forn J; Greengard P
Dopamine-sensitive adenylate cyclase and protein phosphorylation in the rat caudate nucleus.
Psychopharmacology bulletin 1975;11(4):10-1.
1975: Kebabian J W; Blood F E; Steiner A L; Greengard P
Neurotransmitters increase cyclic nucleotides in postganglionic neurons: immunocytochemical demonstration.
Science (New York, N.Y.) 1975;190(4210):157-9.
1975: Ueda T; Rudolph S A; Greengard P
Solubilization of a phosphoprotein and its associated cyclic AMP-dependent protein kinase and phosphoprotein phosphatase from synaptic membrane fractions, and some kinetic evidence for their existence as a complex.
Archives of biochemistry and biophysics 1975;170(2):492-503.
1975: Clement-Cormier Y C; Parrish R G; Petzold G L; Kerabian J W; Greengard P
Characterization of a dopamine-sensitive adenylate cyclase in the rat caudate nucleus.
Journal of neurochemistry 1975;25(2):143-9.
1975: Pomerantz A H; Rudolph S A; Haley B E; Greengard P
Photoaffinity labeling of a protein kinase from bovine brain with 8-azidoadenosine 3',5'-monophosphate.
Biochemistry 1975;14(17):3858-62.
1975: Kebabian J W; Steiner A L; Greengard P
Muscarinic cholinergic regulation of cyclic guanosine 3,5-monophosphate in autonomic ganglia: possible role in synaptic transmission.
The Journal of pharmacology and experimental therapeutics 1975;193(2):474-88.
1975: Greengard P
Antipsychotic drugs: roles of cyclic AMP.
Psychopharmacology bulletin 1975;11(2):45.
1975: Morgenroth V H; Hegstrand L R; Roth R H; Greengard P
Evidence for involvement of protein kinase in the activation by adenosine 3':5'-monophosphate of brain tyrosine 3-monooxygenase.
The Journal of biological chemistry 1975;250(5):1946-8.
1975: Malkinson A M; Krueger B K; Rudolph S A; Casnellie J E; Haley B E; Greengard P
Widespread occurrence of a specific protein in vertebrate tissues and regulation by cyclic AMP of its endogenous phosphorylation and dephosphorylation.
Metabolism: clinical and experimental 1975;24(3):331-41.
1975: Walton K G; DeLorenzo R J; Curran P F; Greengard P
Regulation of protein phosphorylation and sodium transport in toad bladder.
The Journal of general physiology 1975;65(2):153-77.
1975: Sloboda R D; Rudolph S A; Rosenbaum J L; Greengard P
Cyclic AMP-dependent endogenous phosphorylation of a microtubule-associated protein.
Proceedings of the National Academy of Sciences of the United States of America 1975;72(1):177-81.
1975: Kebabian J W; Clement-Cormier Y C; Petzold G L; Greengard P
Chemistry of dopamine receptors.
Advances in neurology 1975;9():1-11.
1975: Greengard P
Cyclic nucleotides, protein phosphorylation, and neuronal function.
Advances in cyclic nucleotide research 1975;5():585-601.
1974: Forn J; Krueger B K; Greengard P
Adenosine 3',5'-monophosphate content in rat caudate nucleus: demonstration of dopaminergic and adrenergic receptors.
Science (New York, N.Y.) 1974;186(4169):1118-20.
1974: Weight F F; Petzold G; Greengard P
Guanosine 3',5'-monophosphate in sympathetic ganglia: increase assoicated with synaptic transmission.
Science (New York, N.Y.) 1974;186(4167):942-4.
1974: Maeno H; Reyes P L; Ueda T; Rudolph S A; Greengard P
Autophosphorylation of adenosine 3',5'-monophosphate-dependent protein kinase from bovine brain.
Archives of biochemistry and biophysics 1974;164(2):551-9.
1974: Liu A Y; Greengard P
Aldosterone-induced increase in protein phosphatase activity of toad bladder.
Proceedings of the National Academy of Sciences of the United States of America 1974;71(10):3869-73.
1974: Rudolph S A; Greengard P
Regulation of protein phosphorylation and membrane permeability by beta-adrenergic agents and cyclic adenosine 3':5'-monophosphate in the avian erythrocyte.
The Journal of biological chemistry 1974;249(17):5684-7.
1974: Casnellie J E; Greengard P
Guanosine 3':5'-cyclic monophosphate-dependent phosphorylation of endogenous substrate proteins in membranes of mammalian smooth muscle.
Proceedings of the National Academy of Sciences of the United States of America 1974;71(5):1891-5.
1974: Greengard P; Kebabian J W
Role of cyclic AMP in synaptic transmission in the mammalian peripheral nervous system.
Federation proceedings 1974;33(4):1059-67.
1974: Clement-Cormier Y C; Kebabian J W; Petzold G L; Greengard P
Dopamine-sensitive adenylate cyclase in mammalian brain: a possible site of action of antipsychotic drugs.
Proceedings of the National Academy of Sciences of the United States of America 1974;71(4):1113-7.
1974: Nathanson J A; Greengard P
Serotonin-sensitive adenylate cyclase in neural tissue and its similarity to the serotonin receptor: a possible site of action of lysergic acid diethylamide.
Proceedings of the National Academy of Sciences of the United States of America 1974;71(3):797-801.
1974: Kalix P; McAfee D A; Schorderet M; Greengard P
Pharmacological analysis of synaptically mediated increase in cyclic adenosine monophosphate in rabbit superior cervical ganglion.
The Journal of pharmacology and experimental therapeutics 1974;188(3):676-87.
1974: Kuo J F; Greengard P
Assay of cyclic GMP by activation of cyclic GMP-dependent protein kinase.
Methods in enzymology 1974;38():90-5.
1974: Kuo J F; Greengard P
Purification and characterization of cyclic GMP-dependent protein kinases.
Methods in enzymology 1974;38():329-50.
1974: Greengard P
Biochemical characterization of the dopamine receptor in the mammalian caudate nucleus.
Journal of psychiatric research 1974;11():87-90.
1973: Ueda T; Maeno H; Greengard P
Regulation of endogenous phosphorylation of specific proteins in synaptic membrane fractions from rat brain by adenosine 3':5'-monophosphate.
The Journal of biological chemistry 1973;248(23):8295-305.
1973: Delorenzo R J; Greengard P
Activation by adenosine 3':5'-monophosphate of a membrane-bound phosphoprotein phosphatase from toad bladder.
Proceedings of the National Academy of Sciences of the United States of America 1973;70(6):1831-5.
1973: Nathanson J A; Greengard P
Octopamine-sensitive adenylate cyclse: evidence for a biological role of octopamine in nervous tissue.
Science (New York, N.Y.) 1973;180(83):308-10.
1973: DeLorenzo R J; Walton K G; Curran P F; Greengard P
Regulation of phosphorylation of a specific protein in toad-bladder membrane by antidiuretic hormone and cyclic AMP, and its possible relationship to membrane permeability changes.
Proceedings of the National Academy of Sciences of the United States of America 1973;70(3):880-4.
1973: Donnelly T E; Kuo J F; Miyamoto E; Greengard P
Protein kinase modulator from lobster tail muscle. II. Effects of the modulator on holoenzyme and catalytic subunit of guanosine 3',5'-monophosphate-dependent and adenosine 3',5'-monophosphate-dependent protein kinases.
The Journal of biological chemistry 1973;248(1):199-203.
1973: Donnelly T E; Kuo J F; Reyes P L; Liu Y P; Greengard P
Protein kinase modulator from lobster tail muscle. I. Stimulatory and inhibitory effects of the modulator on the phosphorylation of substrate proteins by guanosine 3',5'-monophosphate-dependent and adenosine 3',5'-monophosphate-dependent protein kinases.
The Journal of biological chemistry 1973;248(1):190-8.
1973: Miyamoto E; Petzold G L; Kuo J F; Greengard P
Dissociation and activation of adenosine 3',5'-monophosphate-dependent and guanosine 3',5'-monophosphate-dependent protein kinases by cyclic nucleotides and by substrate proteins.
The Journal of biological chemistry 1973;248(1):179-89.
1972: Tsien R W; Giles W; Greengard P
Cyclic AMP mediates the effects of adrenaline on cardiac purkinje fibres.
Nature: New biology 1972;240(101):181-3.
1972: Lee T P; Kuo J F; Greengard P
Role of muscarinic cholinergic receptors in regulation of guanosine 3':5'-cyclic monophosphate content in mammalian brain, heart muscle, and intestinal smooth muscle.
Proceedings of the National Academy of Sciences of the United States of America 1972;69(11):3287-91.
1972: McAfee D A; Greengard P
Adenosine 3',5'-monophosphate: electrophysiological evidence for a role in synaptic transmission.
Science (New York, N.Y.) 1972;178(58):310-2.
1972: Johnson E M; Ueda T; Maeno H; Greengard P
Adenosine 3',5-monophosphate-dependent phosphorylation of a specific protein in synaptic membrane fractions from rat cerebrum.
The Journal of biological chemistry 1972;247(17):5650-2.
1972: Kebabian J W; Petzold G L; Greengard P
Dopamine-sensitive adenylate cyclase in caudate nucleus of rat brain, and its similarity to the "dopamine receptor".
Proceedings of the National Academy of Sciences of the United States of America 1972;69(8):2145-9.
1972: Greengard P
Adenosine 3':5'-cyclic monophosphate as a mediator in the action of neurohumoral agents.
The Biochemical journal 1972;128(3):75P-77P.
1972: Maeno H; Greengard P
Phosphoprotein phosphatases from rat cerebral cortex. Subcellular distribution and characterization.
The Journal of biological chemistry 1972;247(10):3269-77.
1972: Kuo J F; Lee T P; Reyes P L; Walton K G; Donnelly T E; Greengard P
Cyclic nucleotide-dependent protein kinases. X. An assay method for the measurement of quanosine 3',5'-monophosphate in various biological materials and a study of agents regulating its levels in heart and brain.
The Journal of biological chemistry 1972;247(1):16-22.
1972: Greengard P; McAfee D A
Adenosine 3':5'-cyclic monophosphate as a mediator in the action of neurohumoral agents.
Biochemical Society symposium 1972;(36):87-102.
1972: Greengard P; McAfee D A; Kebabian J W
On the mechanism of action of cyclic AMP and its role in synaptic transmission.
Advances in cyclic nucleotide research 1972;1():337-55.
1972: Kuo J F; Greengard P
An assay method for cyclic AMP and cyclic GMP based upon their abilities to activate cyclic AMP-dependent and cyclic GMP-dependent protein kinases.
Advances in cyclic nucleotide research 1972;2():41-50.
1972: Kebabian J W; Kuo J F; Greengard P
Determination of relative levels of cyclic AMP in tissues or cells prelabeled with radioactive adenine.
Advances in cyclic nucleotide research 1972;2():131-7.
1971: Kebabian J W; Greengard P
Dopamine-sensitive adenyl cyclase: possible role in synaptic transmission.
Science (New York, N.Y.) 1971;174(16):1346-9.
1971: Johnson E M; Maeno H; Greengard P
Phosphorylation of endogenous protein of rat brain by cyclic adenosine 3',5'-monophosphate-dependent protein kinase.
The Journal of biological chemistry 1971;246(24):7731-9.
1971: Kuo J F; Wyatt G R; Greengard P
Cyclic nucleotide-dependent protein kinases. IX. Partial purification and some properties of guanosine 3',5'-monophosphate-dependent and adenosine 3',5'-monophosphate-dependent protein kinases from various tissues and species of Arthropoda.
The Journal of biological chemistry 1971;246(23):7159-67.
1971: Greengard P
On the reactivity and mechanism of action of cyclic nucleotides.
Annals of the New York Academy of Sciences 1971;185():18-26.
1971: Lee T P; Kuo J F; Greengard P
Regulation of myocardial cyclic AMP by isoproterenol, glucagon and acetylcholine.
Biochemical and biophysical research communications 1971;45(4):991-7.
1971: Lukas G; Brindle S D; Greengard P
The route of absorption of intraperitoneally administered compounds.
The Journal of pharmacology and experimental therapeutics 1971;178(3):562-4.
1971: Hayaishi O; Greengard P; Colowick S P
On the equilibrium of the adenylate cyclase reaction.
The Journal of biological chemistry 1971;246(18):5840-3.
1971: Florendo N T; Barrnett R J; Greengard P
Cyclic 3',5'-nucleotide phosphodiesterase: cytochemical localization in cerebral cortex.
Science (New York, N.Y.) 1971;173(998):745-7.
1971: Miyamoto E; Petzold G L; Harris J S; Greengard P
Dissociation and concomitant activation of adenosine 3',5'-monophosphate-dependent protein kinase by histone.
Biochemical and biophysical research communications 1971;44(2):305-12.
1971: Rudolph S A; Johnson E M; Greengard P
The enthalpy of hydrolysis of various 3',5'-and 2',3'-cyclic nucleotides.
The Journal of biological chemistry 1971;246(5):1271-3.
1971: McAfee D A; Schorderet M; Greengard P
Adenosine 3',5'-monophosphate in nervous tissue: increase associated with synaptic transmission.
Science (New York, N.Y.) 1971;171(976):1156-8.
1971: Whittaker V P; Greengard P
The isolation of synaptosomes from the brain of a teleost fish, Centriopristes striatus.
Journal of neurochemistry 1971;18(2):173-6.
1971: Maeno H; Johnson E M; Greengard P
Subcellular distribution of adenosine 3',5'-monophosphate-dependent protein kinase in rat brain.
The Journal of biological chemistry 1971;246(1):134-42.
1970: Kuo J F; Greengard P
Stimulation of adenosine 3',5'-monophosphate-dependent and guanosine 3',5'-monophosphate-dependent protein kinases by some analogs of adenosine 3',5'-monophosphate.
Biochemical and biophysical research communications 1970;40(5):1032-8.
1970: Kuo J F; Greengard P
Cyclic nucleotide-dependent protein kinases. VII. Comparison of various histones as substrates for adenosine 3',5'-monophosphate-dependent and guanosine 3',5'-monophosphate-dependent protein kinases.
Biochimica et biophysica acta 1970;212(3):434-40.
1970: Kuo J F; Greengard P
Cyclic nucleotide-dependent protein kinases. 8. An assay method for the measurement of adenosine 3',5'-monophosphate in various tissues and a study of agents influencing its level in adipose cells.
The Journal of biological chemistry 1970;245(16):4067-73.
1970: Kuo J F; Krueger B K; Sanes J R; Greengard P
Cyclic nucleotide-dependent protein kinases. V. Preparation and properties of adenosine 3',5'-monophosphate-dependent protein kinase from various bovine tissues.
Biochimica et biophysica acta 1970;212(1):79-91.
1970: Kuo J F; Greengard P
Cyclic nucleotide-dependent protein kinases. VI. Isolation and partial purification of a protein kinase activated by guanosine 3',5'-monophosphate.
The Journal of biological chemistry 1970;245(10):2493-8.
1970: Reik L; Petzold G L; Higgins J A; Greengard P; Barrnett R J
Hormone-sensitive adenyl cyclase: cytochemical localization in rat liver.
Science (New York, N.Y.) 1970;168(929):382-4.
1970: Greengard P; Kuo J F
On the mechanism of action of cyclic AMP.
Advances in biochemical psychopharmacology 1970;3():287-306.
1970: Greengard P; Kuo J F; Miyamoto E
Studies on the mechanism of action of cyclic AMP in nervous and other tissues.
Advances in enzyme regulation 1970;9():113-25.
1969: Kuo J F; Greengard P
Cyclic nucleotide-dependent protein kinases. IV. Widespread occurrence of adenosine 3',5'-monophosphate-dependent protein kinase in various tissues and phyla of the animal kingdom.
Proceedings of the National Academy of Sciences of the United States of America 1969;64(4):1349-55.
1969: Miyamoto E; Kuo J F; Greengard P
Cyclic nucleotide-dependent protein kinases. 3. Purification and properties of adenosine 3',5'-monophosphate-dependent protein kinase from bovine brain.
The Journal of biological chemistry 1969;244(23):6395-402.
1969: den Hertog A; Greengard P; Ritchie J M
On the metabolic basis of nervous activity.
The Journal of physiology 1969;204(3):511-21.
1969: Greengard P; Rudolph S A; Sturtevant J M
Enthalpy of hydrolysis of the 3' bond of adenosine 3',5'-monophosphate and guanosine 3',5'-monophosphate.
The Journal of biological chemistry 1969;244(17):4798-800.
1969: Kuo J F; Greengard P
An adenosine 3',5'-monophosphate-dependent protein kinase from Escherichia coli.
The Journal of biological chemistry 1969;244(12):3417-9.
1969: Greengard P; Petrack B; Kalinsky H J
Identification of hormonally controlled endogenous inhibitor of livernicotinamide deamidase.
Biochimica et biophysica acta 1969;184(1):148-53.
1968: Greengard P; Kalinsky H; Manning T J; Zak S B
Prevention and remission by adrenocortical steriods of nicotinamide deficiency disease. II. A study of the mechanism.
The Journal of biological chemistry 1968;243(16):4216-21.
1968: Miyamoto E; Kuo J F; Greengard P
Adenosine 3',5'-monophosphate-dependent protein kinase from brain.
Science (New York, N.Y.) 1968;165(888):63-5.
1968: Greengard P; Kalinsky H J; Manning T J
Tryptophan pyrrolase activity during pregnancy.
Biochimica et biophysica acta 1968;156(1):198-9.
1967: Greengard P; Psychoyos S; Tallan H H; Cooper D Y; Rosenthal O; Estabrook R W
Aldosterone synthesis by adrenal mitochondria. 3. Participation of cytochrome P-450.
Archives of biochemistry and biophysics 1967;121(2):298-303.
1967: Quinn G P; Cohn M M; Reid M B; Greengard P; Weiner M
The effect of formulation on phenmetrazine plasma levels in man studied by a sensitive analytic method.
Clinical pharmacology and therapeutics 1967;8(3):369-73.
1967: Berg B N; Sigg E B; Greengard P
Maintenance of pregnancy in protein-deficient rats by adrenocortical steroid or ACTH administration.
Endocrinology 1967;80(5):829-34.
1967: Tallan H H; Psychoyos S; Greengard P
Aldosterone synthesis by adrenal mitochondria. II. The effect of citric acid cycle intermediates; identification of the soluble stimulatory factor as fumarase.
The Journal of biological chemistry 1967;242(8):1912-4.
1967: Gluecksohn-Waelsch S; Greengard P; Quinn G P; Teicher L S
Genetic variations of an oxidase in mammals.
The Journal of biological chemistry 1967;242(6):1271-3.
1967: Greengard P; Petrack B; Kalinsky H
Effect of hypophysectomy on pyridine nucleotide metabolism. The role of nicotinamide.
The Journal of biological chemistry 1967;242(1):152-4.
1966: Greengard P; Sigg E B; Fratta I; Zak S B
Prevention and remission by adrenocortical steroids of nicotinamide deficiency disorders and of 6-aminonicotinamide toxicity in rats and dogs.
The Journal of pharmacology and experimental therapeutics 1966;154(3):624-31.
1966: Quinn G P; Greengard P; Reid M B
Prevention by antidepressant drugs of reserpine effect on pyridine nucleotide metabolism.
Molecular pharmacology 1966;2(4):347-51.
1966: Quinn G P; Greengard P
The pathway for the biosynthesis of N 1-methyl-4-pyridone-3-carboxamide.
Archives of biochemistry and biophysics 1966;115(1):146-52.
1966: Psychoyos S; Tallan H H; Greengard P
Aldosterone synthesis by adrenal mitochondria.
The Journal of biological chemistry 1966;241(12):2949-56.
1966: Petrack B; Greengard P; Kalinsky H
On the relative efficacy of nicotinamide and nicotinic acid as precursors of nicotinamide adenine dinucleotide.
The Journal of biological chemistry 1966;241(10):2367-72.
1966: Märki F; Greengard P
Nicotinamide deamidase in Ehrlich ascites tumor cells.
Biochimica et biophysica acta 1966;113(3):587-94.
1966: Ritchie J M; Greengard P
On the mode of action of local anesthetics.
Annual review of pharmacology 1966;6():405-30.
1965: Ritchie J M; Ritchie B; Greengard P
The effect of the nerve sheath on the action of local anesthetics.
The Journal of pharmacology and experimental therapeutics 1965;150(1):160-4.
1965: Ritchie J M; Ritchie B; Greengard P
The active structure of local anesthetics.
The Journal of pharmacology and experimental therapeutics 1965;150(1):152-9.
1965: PETRACK B; GREENGARD P; CRASTON A; SHEPPY F
NICOTINAMIDE DEAMIDASE FROM MAMMALIAN LIVER.
The Journal of biological chemistry 1965;240():1725-30.
1965: GREENGARD P; QUINN G P; REID M B
IDENTIFICATION OF HORMONES AFFECTING PYRIDINE NUCLEOTIDE METABOLISM OF RAT LIVER.
The Journal of biological chemistry 1965;240():486-90.
1964: FRATTA I; ZAK S B; GREENGARD P; SIGG E B
FETAL DEATH FROM NICOTINAMIDE-DEFICIENT DIET AND ITS PREVENTION BY CHLORPROMAZINE AND IMIPRAMINE.
Science (New York, N.Y.) 1964;145():1429-30.
1964: GREENGARD P; QUINN G P; REID M B
PITUITARY INFLUENCE OF PYRIDINE NUCLEOTIDE METABOLISM OF RAT LIVER.
The Journal of biological chemistry 1964;239():1887-92.
1963: ZAK S B; TALLAN H H; QUINN G P; FRATTA I; GREENGARD P
THE DETERMINATION AND PHYSIOLOGICAL DISTRIBUTION OF DIPYRIDAMOLE AND ITS GLUCURONIDES IN BIOLOGICAL MATERIAL.
The Journal of pharmacology and experimental therapeutics 1963;141():392-8.
1962: GREENGARD P; STRAUB R W
Metabolic studies on the hyperpolarization following activity in mammalian non-myelinated nerve fibres.
The Journal of physiology 1962;161():414-23.
1962: GREENGARD P; QUINN G P
Metabolic effects of tranquilizers and hypophysectomy.
Annals of the New York Academy of Sciences 1962;96():179-84.
1961: GREENGARD P; KALINSK Y H; PETRACK B
Effect of hypophysectomy on liver diphosphopyridine nucleotide: the role of nicotinamide.
Biochimica et biophysica acta 1961;52():408-9.
1961: RITCHIE J M; GREENGARD P
On the active structure of local anesthetics.
The Journal of pharmacology and experimental therapeutics 1961;133():241-5.
1961: GREENGARD P; QUINN G P; LANDRAU M A
Hormonal effects on DPN concentration in rat liver.
Biochimica et biophysica acta 1961;47():614-6.
1960: CHIRIGOS M A; GREENGARD P; UDENFRIEND S
Uptake of tyrosine by rat brain in vivo.
The Journal of biological chemistry 1960;235():2075-9.
1959: GREENGARD P; MINNAERT K; SLATER E C; BETEL I
Yield of oxidative phosphorylation associated with the oxidation of succinate to fumarate.
The Biochemical journal 1959;73():637-46.
1959: GREENGARD P; STRAUB R W
Effect of frequency of electrical stimulation on the concentration of intermediary metabolites in mammalian non-myelinated fibres.
The Journal of physiology 1959;148():353-61.
1959: GREENGARD P; STRAUB R W
Restoration by barium of action potentials in sodium-deprived mammalian B and C fibres.
The Journal of physiology 1959;145(3):562-9.
1958: GREENGARD P; STRAUB R W
After-potentials in mammalian non-myelinated nerve fibres.
The Journal of physiology 1958;144(3):442-62.
1958: GREENGARD P; STRAUB R W
Effect of electrical stimulation on the concentration of phosphorylated intermediary metabolites in mammalian non-myelinated fibres.
The Journal of physiology 1958;140(1):18-9P.
1956: GREENGARD P
Determination of intermediary metabolites by enzymic fluorimetry.
Nature 1956;178(4534):632-4.
1954: GREENGARD P; BRINK F; COLOWICK S P
Some relationships between action potential, oxygen consumption and coenzyme content in degenerating peripheral axons.
Journal of cellular physiology 1954;44(3):395-420.

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