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Paul Greengard

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Yong-Seok Oh; Dinshaw J Patel; Ji-Seon Seo; Xiaozhu Zhang; Jung-Hyuck Ahn; Ilaria Ceglia; Brian T Chait; Pu Gao; Yong Kim; Ko-Woon Lee; Paul Greengard
SMARCA3, a chromatin-remodeling factor, is required for p11-dependent antidepressant action.
Paul Greengard
A conversation with Paul Greengard. Interview by Eric J Nestler.
Thomas Liebmann; Lena Scott; Nermin Sourial-Bassillious; Per Svenningsson; Alexander Bondar; Hjalmar Brismar; Marc Flajolet; Paul Greengard; Markus Kruusmägi; Anita Aperia
A noncanonical postsynaptic transport route for a GPCR belonging to the serotonin receptor family.

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2013: Yong-Seok Oh; Dinshaw J Patel; Ji-Seon Seo; Xiaozhu Zhang; Jung-Hyuck Ahn; Ilaria Ceglia; Brian T Chait; Pu Gao; Yong Kim; Ko-Woon Lee; Paul Greengard
SMARCA3, a chromatin-remodeling factor, is required for p11-dependent antidepressant action.
Cell 2013;152(4):831-43.
2013: Paul Greengard
A conversation with Paul Greengard. Interview by Eric J Nestler.
Annual review of pharmacology and toxicology 2013;53():1-16.
2012: Thomas Liebmann; Lena Scott; Nermin Sourial-Bassillious; Per Svenningsson; Alexander Bondar; Hjalmar Brismar; Marc Flajolet; Paul Greengard; Markus Kruusmägi; Anita Aperia
A noncanonical postsynaptic transport route for a GPCR belonging to the serotonin receptor family.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2012;32(50):17998-8008.
2012: Karima Bettayeb; Victor Bustos; Hervé Galons; Paul Greengard; Wenjie Luo; Laurent Meijer; Nassima Oumata; Yuanyuan Zhang; Marc Flajolet
Small-molecule inducers of Aβ-42 peptide production share a common mechanism of action.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2012;26(12):5115-23.
2012: Emanuela Santini; Helen Bateup; Michael Feyder; Giuseppe Gangarossa; Paul Greengard; Gilberto Fisone
Dopamine- and cAMP-regulated phosphoprotein of 32-kDa (DARPP-32)-dependent activation of extracellular signal-regulated kinase (ERK) and mammalian target of rapamycin complex 1 (mTORC1) signaling in experimental parkinsonism.
The Journal of biological chemistry 2012;287(33):27806-12.
2012: Alana G Lerner; Yoshimi Nakagawa; Vinh Nguyen; Scott A Oakes; Bradley J Backes; Rajarshi Ghosh; Paul Greengard; Myriam Heiman; Nathaniel Heintz; Simon Hui; Aeid Igbaria; P V K Praveen; Sarah Shen; Qizhi Tang; Ala Trusina; John-Paul Upton; Feroz R Papa
IRE1α induces thioredoxin-interacting protein to activate the NLRP3 inflammasome and promote programmed cell death under irremediable ER stress.
Cell metabolism 2012;16(2):250-64.
2012: Jennifer Schmidt; Margarita Arango-Lievano; Nathaniel Heintz; Ines Ibañez-Tallon; Michael Gordon Kaplitt; John J Marshall; Amanda J Rubin; Eric F Schmidt; Paul Greengard
Cholinergic interneurons in the nucleus accumbens regulate depression-like behavior.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(28):11360-5.
2012: C Savio Chan; Qiaoling Cui; Tracy S Gertler; Kelly E Glajch; Paul Greengard; Myriam Heiman; Nathaniel Heintz; Jayms D Peterson; Joshua L Plotkin; Ruth E Quintana; Luke E Sebel; Weixing Shen; Dalton Surmeier
Strain-specific regulation of striatal phenotype in Drd2-eGFP BAC transgenic mice.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2012;32(27):9124-32.
2012: Eric F Schmidt; Jennifer L Warner-Schmidt; Paul Greengard; Benjamin G Otopalik; Sarah B Pickett; Nathaniel Heintz
Identification of the cortical neurons that mediate antidepressant responses.
Cell 2012;149(5):1152-63.
2012: Yunjia Chen; Christopher Cottingham; Paul Greengard; Kai Jiao; Yin Liu; Lori McMahon; Qin Wang
Neurabin scaffolding of adenosine receptor and RGS4 regulates anti-seizure effect of endogenous adenosine.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2012;32(8):2683-95.
2012: Mahomi Kuroiwa; Angus C Nairn; Takahide Shuto; Gretchen L Snyder; Yuchio Yanagawa; David R Benavides; James A Bibb; Atsuo Fukuda; Paul Greengard; Akinori Nishi
Phosphodiesterase 4 inhibition enhances the dopamine D1 receptor/PKA/DARPP-32 signaling cascade in frontal cortex.
Psychopharmacology 2012;219(4):1065-79.
2012: Maya M Davis; Paul Greengard; Peter Olausson; Jane R Taylor; Angus C Nairn
Regulator of calmodulin signaling knockout mice display anxiety-like behavior and motivational deficits.
The European journal of neuroscience 2012;35(2):300-8.
2011: Yongfang Zhang; Angus C Nairn; Jian Xu; George M Anderson; Paul Greengard; Pradeep Kurup; Paul J Lombroso
Reduced levels of the tyrosine phosphatase STEP block β amyloid-mediated GluA1/GluA2 receptor internalization.
Journal of neurochemistry 2011;119(3):664-72.
2011: Martin Egeland; Paul Greengard; Jennifer Schmidt; Per Svenningsson
Co-expression of serotonin 5-HT(1B) and 5-HT(4) receptors in p11 containing cells in cerebral cortex, hippocampus, caudate-putamen and cerebellum.
Neuropharmacology 2011;61(3):442-50.
2011: Yuan Tian; Victor Bustos; Marc Flajolet; Paul Greengard
A small-molecule enhancer of autophagy decreases levels of Abeta and APP-CTF via Atg5-dependent autophagy pathway.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2011;25(6):1934-42.
2011: Jennifer Schmidt; Kimberly E Vanover; Emily Y Chen; John J Marshall; Paul Greengard
Antidepressant effects of selective serotonin reuptake inhibitors (SSRIs) are attenuated by antiinflammatory drugs in mice and humans.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(22):9262-7.
2011: Daniel J Christoffel; Sam A Golden; Dani Dumitriu; Alfred J Robison; William G Janssen; H Francisca Ahn; Vaishnav Krishnan; Cindy M Reyes; Ming-Hu Han; Jessica L Ables; Amelia J Eisch; David M Dietz; Deveroux Ferguson; Rachael L Neve; Paul Greengard; Yong Kim; John H Morrison; Scott J Russo
IκB kinase regulates social defeat stress-induced synaptic and behavioral plasticity.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2011;31(1):314-21.
2011: S Ivar Walaas; Paul Greengard; Hugh Caroll Hemmings; Angus Clark Nairn
Beyond the dopamine receptor: regulation and roles of serine/threonine protein phosphatases.
Frontiers in neuroanatomy 2011;5():50.
2011: Anne Schaefer; Alexander Tarakhovsky; Paul Greengard
Epigenetic mechanisms of mental retardation.
Progress in drug research. Fortschritte der Arzneimittelforschung. Progrès des recherches pharmaceutiques 2011;67():125-46.
2010: Yongfang Zhang; Pradeep Kurup; Jian Xu; Nikisha Carty; Stephanie M Fernandez; Haakon B Nygaard; Christopher Pittenger; Paul Greengard; Stephen M Strittmatter; Angus Nairn; Paul J Lombroso
Genetic reduction of striatal-enriched tyrosine phosphatase (STEP) reverses cognitive and cellular deficits in an Alzheimer's disease mouse model.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(44):19014-9.
2010: Hong Wang; Yi Nong; Fernando Bazan; Paul Greengard; Marc Flajolet
Norbin: A promising central nervous system regulator.
Communicative & integrative biology 2010;3(6):487-90.
2010: Katye M Fichter; Marc Flajolet; Paul Greengard; Tothu (Tania) Vu
Kinetics of G-protein-coupled receptor endosomal trafficking pathways revealed by single quantum dots.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(43):18658-63.
2010: Brian Alexander; Jennifer Schmidt; Therese Eriksson; Carol Tamminga; Margarita Arango-Lievano; Margarita Arango-Llievano; Subroto Ghose; Mary Vernov; Mihaela Stavarache; Mihaela Stavarche; Sergei Musatov; Marc Flajolet; Per Svenningsson; Paul Greengard; Michael Gordon Kaplitt
Reversal of depressed behaviors in mice by p11 gene therapy in the nucleus accumbens.
Science translational medicine 2010;2(54):54ra76.
2010: Vincent Paillé; Barbara Picconi; Vincenza Bagetta; Veronica Ghiglieri; Carmelo Sgobio; Massimiliano Di Filippo; Maria T Viscomi; Carmela Giampà; Francesca R Fusco; Fabrizio Gardoni; Giorgio Bernardi; Paul Greengard; Monica Di Luca; Paolo Calabresi
Distinct levels of dopamine denervation differentially alter striatal synaptic plasticity and NMDA receptor subunit composition.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2010;30(42):14182-93.
2010: Jennifer Schmidt; Emily Y Chen; Xiaoqun Zhang; John J Marshall; Alexei Morozov; Per Svenningsson; Paul Greengard
A role for p11 in the antidepressant action of brain-derived neurotrophic factor.
Biological psychiatry 2010;68(6):528-35.
2010: Gen He; Wenjie Luo; Peng Lee (Li); Christine Remmers; William Netzer; Joseph Hendrick; Karima Bettayeb; Marc Flajolet; Fred Gorelick; Lawrence Wennogle; Paul Greengard
Gamma-secretase activating protein is a therapeutic target for Alzheimer's disease.
Nature 2010;467(7311):95-8.
2010: Anne Schaefer; Heh-In Im; Morten T Venø; Christie D Fowler; Alice Min; Adam Intrator; Jørgen Kjems; Paul J Kenny; Dónal O'Carroll; Paul Greengard
Argonaute 2 in dopamine 2 receptor-expressing neurons regulates cocaine addiction.
The Journal of experimental medicine 2010;207(9):1843-51.
2010: Jacob Bendor; José E Lizardi-Ortiz; Robert I Westphalen; Markus Brandstetter; Hugh C Hemmings; David Sulzer; Marc Flajolet; Paul Greengard
AGAP1/AP-3-dependent endocytic recycling of M5 muscarinic receptors promotes dopamine release.
The EMBO journal 2010;29(16):2813-26.
2010: Helen Bateup; Emanuela Santini; Weixing Shen; Shari Birnbaum; Emmanuel Valjent; Dalton Surmeier; Gilberto Fisone; Eric J Nestler; Paul Greengard
Distinct subclasses of medium spiny neurons differentially regulate striatal motor behaviors.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(33):14845-50.
2010: Marc Flajolet; Hong Wang; Paul Greengard
[mGluR5: a receptor at the therapeutic crossroad?].
Médecine sciences : M/S 2010;26(8-9):678-80.
2010: Hugh C Hemmings; Paul Greengard
Positively active: how local anesthetics work.
Anesthesiology 2010;113(1):250-2.
2010: Ilaria Ceglia; Yong Kim; Angus Nairn; Paul Greengard
Signaling pathways controlling the phosphorylation state of WAVE1, a regulator of actin polymerization.
Journal of neurochemistry 2010;114(1):182-90.
2010: Martin Egeland; Jennifer Schmidt; Paul Greengard; Per Svenningsson
Neurogenic effects of fluoxetine are attenuated in p11 (S100A10) knockout mice.
Biological psychiatry 2010;67(11):1048-56.
2010: P H Gleick; R M Adams; R M Amasino; E Anders; D J Anderson; W W Anderson; L E Anselin; M K Arroyo; B Asfaw; F J Ayala; A Bax; A J Bebbington; G Bell; M V L Bennett; Jeffrey L Bennetzen; M R Berenbaum; O B Berlin; P J Bjorkman; E Blackburn; J E Blamont; M R Botchan; J S Boyer; E A Boyle; D Branton; S P Briggs; W R Briggs; W J Brill; R J Britten; W S Broecker; J H Brown; P O Brown; A T Brunger; J Cairns; D E Canfield; S R Carpenter; J C Carrington; A R Cashmore; J C Castilla; A Cazenave; F S Chapin; A J Ciechanover; D E Clapham; W C Clark; R N Clayton; M D Coe; E M Conwell; E B Cowling; R M Cowling; C S Cox; R B Croteau; D M Crothers; P J Crutzen; G C Daily; G B Dalrymple; J L Dangl; S A Darst; D R Davies; M B Davis; Pietro De Camilli; C Dean; R S DeFries; J Deisenhofer; D P Delmer; E F DeLong; D J DeRosier; T O Diener; R Dirzo; J E Dixon; M J Donoghue; R F Doolittle; T Dunne; P R Ehrlich; S N Eisenstadt; T Eisner; K A Emanuel; S W Englander; W G Ernst; P G Falkowski; G Feher; J A Ferejohn; A Fersht; E H Fischer; R Fischer; K V Flannery; J Frank; P A Frey; I Fridovich; C Frieden; D J Futuyma; W R Gardner; C J R Garrett; W Gilbert; R B Goldberg; W H Goodenough; C S Goodman; M Goodman; Paul Greengard; S Hake; G Hammel; S Hanson; S C Harrison; S R Hart; D L Hartl; R Haselkorn; K Hawkes; J M Hayes; B Hille; T Hökfelt; J S House; M Hout; D M Hunten; I A Izquierdo; A T Jagendorf; D H Janzen; R Jeanloz; C S Jencks; W A Jury; H R Kaback; T Kailath; P Kay; S A Kay; D Kennedy; A Kerr; R C Kessler; G S Khush; S W Kieffer; P V Kirch; K Kirk; M G Kivelson; J P Klinman; A Klug; L Knopoff; H Kornberg; J E Kutzbach; J C Lagarias; K Lambeck; A Landy; C H Langmuir; B A Larkins; X T Le Pichon; R E Lenski; E B Leopold; S A Levin; M Levitt; G E Likens; J Lippincott-Schwartz; L Lorand; C O Lovejoy; M Lynch; A L Mabogunje; T F Malone; S Manabe; J Marcus; D S Massey; J C McWilliams; E Medina; H J Melosh; D J Meltzer; C D Michener; E L Miles; H A Mooney; P B Moore; F M M Morel; E S Mosley-Thompson; B Moss; W H Munk; N Myers; G B Nair; Jeremy Nathans; E W Nester; R A Nicoll; R P Novick; J F O'Connell; P E Olsen; N D Opdyke; G F Oster; E Ostrom; N R Pace; R T Paine; R D Palmiter; J Pedlosky; G A Petsko; G H Pettengill; S G Philander; D R Piperno; T D Pollard; P B Price; P A Reichard; B F Reskin; R E Ricklefs; R L Rivest; J D Roberts; A K Romney; M G Rossmann; D W Russell; W J Rutter; J A Sabloff; R Z Sagdeev; M D Sahlins; A Salmond; Joshua R Sanes; R Schekman; J Schellnhuber; D W Schindler; J Schmitt; S H Schneider; Vern L Schramm; R R Sederoff; C J Shatz; F Sherman; R L Sidman; K Sieh; E L Simons; B H Singer; M F Singer; B Skyrms; N H Sleep; B D Smith; S H Snyder; R R Sokal; C S Spencer; T A Steitz; K B Strier; T C Südhof; S S Taylor; J Terborgh; D H Thomas; L G Thompson; R T Tjian; M G Turner; S Uyeda; J W Valentine; J S Valentine; J L Van Etten; K E van Holde; M Vaughan; S Verba; P H von Hippel; D B Wake; A Walker; J E Walker; E B Watson; P J Watson; D Weigel; S R Wessler; M J West-Eberhard; T D White; W J Wilson; R V Wolfenden; J A Wood; G M Woodwell; H E Wright; C Wu; C Wunsch; M L Zoback
Climate change and the integrity of science.
Science (New York, N.Y.) 2010;328(5979):689-90.
2010: J R Glausier; M Maddox; H C Hemmings; Angus Nairn; Paul Greengard; E Chris Muly
Localization of dopamine- and cAMP-regulated phosphoprotein-32 and inhibitor-1 in area 9 of Macaca mulatta prefrontal cortex.
Neuroscience 2010;167(2):428-38.
2010: Masato Hara; Ryuichi Fukui; Eriko Hieda; Mahomi Kuroiwa; Helen S Bateup; Tatsuhiko Kano; Paul Greengard; Akinori Nishi
Role of adrenoceptors in the regulation of dopamine/DARPP-32 signaling in neostriatal neurons.
Journal of neurochemistry 2010;113(4):1046-59.
2010: Yong Zhang; Kun Chen; Matthew Baron; Merilee A Teylan; Yong Kim; Zhihuan Song; Paul Greengard; Stephen Wong
A neurocomputational method for fully automated 3D dendritic spine detection and segmentation of medium-sized spiny neurons.
NeuroImage 2010;50(4):1472-84.
2010: Pradeep Kurup; Yongfang Zhang; Jian Xu; Deepa V Venkitaramani; Vahram Haroutunian; Paul Greengard; Angus Nairn; Paul J Lombroso
Abeta-mediated NMDA receptor endocytosis in Alzheimer's disease involves ubiquitination of the tyrosine phosphatase STEP61.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2010;30(17):5948-57.
2010: Barbara Porton; R M Rodriguiz; L E Phillips; J W Gilbert; J Feng; Paul Greengard; Hung-Teh Kao; W C Wetsel
Mice lacking synapsin III show abnormalities in explicit memory and conditioned fear.
Genes, brain, and behavior 2010;9(3):257-68.
2010: Mingming Zhou; Heike Rebholz; Christine Brocia; Jennifer Schmidt; Allen Fienberg; Angus Nairn; Paul Greengard; Marc Flajolet
Forebrain overexpression of CK1delta leads to down-regulation of dopamine receptors and altered locomotor activity reminiscent of ADHD.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(9):4401-6.
2010: Ian Maze; Herbert E Covington; David M Dietz; Quincey LaPlant; William Renthal; Scott J Russo; Max Mechanic; Ezekiell Mouzon; Rachael L Neve; Stephen Haggarty; Yanhua Ren; Srihari C Sampath; Yasmin L Hurd; Paul Greengard; Alexander Tarakhovsky; Anne Schaefer; Eric J Nestler
Essential role of the histone methyltransferase G9a in cocaine-induced plasticity.
Science (New York, N.Y.) 2010;327(5962):213-6.
2010: William Netzer; Craig Powell; Yi Nong; Jacqueline Blundell; Lili Wong; Karen Duff; Marc Flajolet; Paul Greengard
Lowering beta-amyloid levels rescues learning and memory in a Down syndrome mouse model.
PloS one 2010;5(6):e10943.
2010: Emmanuel Valjent; Jesus Bertran-Gonzalez; Benjamin Aubier; Paul Greengard; Denis Hervé; Jean-Antoine Girault
Mechanisms of locomotor sensitization to drugs of abuse in a two-injection protocol.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2010;35(2):401-15.
2009: Hong Wang; Linda Westin; Yi Nong; Shari Birnbaum; Jacob Bendor; Hjalmar Brismar; Eric Nestler; Anita Aperia; Marc Flajolet; Paul Greengard
Norbin is an endogenous regulator of metabotropic glutamate receptor 5 signaling.
Science (New York, N.Y.) 2009;326(5959):1554-7.
2009: Anne Schaefer; Srihari C Sampath; Adam Intrator; Alice Min; Tracy S Gertler; Dalton Surmeier; Alexander Tarakhovsky; Paul Greengard
Control of cognition and adaptive behavior by the GLP/G9a epigenetic suppressor complex.
Neuron 2009;64(5):678-91.
2009: Yun-Wu Zhang; Shijie Liu; Xue Zhang; Wu-Bo Li; Yaomin Chen; Xiumei Huang; Liangwu Sun; Wenjie Luo; William J Netzer; Richard Threadgill; Gordon Wiegand; Ruishan Wang; Stanley N Cohen; Paul Greengard; Francesca-Fang Liao; Limin Li; Huaxi Xu
A functional mouse retroposed gene Rps23r1 reduces Alzheimer's beta-amyloid levels and tau phosphorylation.
Neuron 2009;64(3):328-40.
2009: Christian Hansen; Jill Howlin; Anders Tengholm; Oleg Dyachok; Wolfgang F Vogel; Angus Nairn; Paul Greengard; Tommy Andersson
Wnt-5a-induced phosphorylation of DARPP-32 inhibits breast cancer cell migration in a CREB-dependent manner.
The Journal of biological chemistry 2009;284(40):27533-43.
2009: Heike Rebholz; Akinori Nishi; Sabine Liebscher; Angus Nairn; Marc Flajolet; Paul Greengard
CK2 negatively regulates Galphas signaling.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(33):14096-101.
2009: Jesus Bertran-Gonzalez; Kerstin Håkansson; Anders Borgkvist; Theano Irinopoulou; Karen Brami-Cherrier; Alessandro Usiello; Paul Greengard; Denis Hervé; Jean-Antoine Girault; Emmanuel Valjent; Gilberto Fisone
Histone H3 phosphorylation is under the opposite tonic control of dopamine D2 and adenosine A2A receptors in striatopallidal neurons.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2009;34(7):1710-20.
2009: Ayse B Tekinay; Yi Nong; Julie M Miwa; Ivo Lieberam; Ines Ibanez-Tallon; Paul Greengard; Nathaniel Heintz
A role for LYNX2 in anxiety-related behavior.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(11):4477-82.
2009: Thomas McAvoy; Ming-ming Zhou; Paul Greengard; Angus Nairn
Phosphorylation of Rap1GAP, a striatally enriched protein, by protein kinase A controls Rap1 activity and dendritic spine morphology.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(9):3531-6.
2009: Shogo Endo; Fumihiro Shutoh; TUNG LE; Takehito Okamoto; Toshio Ikeda; Michiyuki Suzuki; Shigenori Kawahara; Dai Yanagihara; Yamato Sato; Kazuyuki Yamada; Toshiro Sakamoto; Yutaka Kirino; Nicholas A Hartell; Kazuhiko Yamaguchi; Shigeyoshi Itohara; Angus Nairn; Paul Greengard; Soichi Nagao; Masao Ito
Dual involvement of G-substrate in motor learning revealed by gene deletion.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(9):3525-30.
2009: Yong Kim; Merilee A Teylan; Matthew Baron; Adam Sands; Angus Nairn; Paul Greengard
Methylphenidate-induced dendritic spine formation and DeltaFosB expression in nucleus accumbens.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(8):2915-20.
2009: Jennifer Schmidt; Marc Flajolet; Abigail Maller; Emily Y Chen; Hongshi Qi; Per Svenningsson; Paul Greengard
Role of p11 in cellular and behavioral effects of 5-HT4 receptor stimulation.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2009;29(6):1937-46.
2009: Emanuela Santini; Cristina Alcacer; Silvia Cacciatore; Myriam Heiman; Denis Hervé; Paul Greengard; Jean-Antoine Girault; Emmanuel Valjent; Gilberto Fisone
L-DOPA activates ERK signaling and phosphorylates histone H3 in the striatonigral medium spiny neurons of hemiparkinsonian mice.
Journal of neurochemistry 2009;108(3):621-33.
2009: Emanuela Santini; Myriam Heiman; Paul Greengard; Emmanuel Valjent; Gilberto Fisone
Inhibition of mTOR signaling in Parkinson's disease prevents L-DOPA-induced dyskinesia.
Science signaling 2009;2(80):ra36.
2009: Odete A B da Cruz e Silva; Sandra Rebelo; Sandra I Vieira; Sam Gandy; Edgar F da Cruz e Silva; Paul Greengard
Enhanced generation of Alzheimer's amyloid-beta following chronic exposure to phorbol ester correlates with differential effects on alpha and epsilon isozymes of protein kinase C.
Journal of neurochemistry 2009;108(2):319-30.
2008: Marc Flajolet; Zhongfeng Wang; Marie Futter; Weixing Shen; Nina Nuangchamnong; Jacob Bendor; Iwona Wallach; Angus Nairn; Dalton Surmeier; Paul Greengard
FGF acts as a co-transmitter through adenosine A(2A) receptor to regulate synaptic plasticity.
Nature neuroscience 2008;11(12):1402-9.
2008: Douglas A Meyer; Edmond Richer; Stanley A Benkovic; Kanehiro Hayashi; Janice W Kansy; Carly F Hale; Lily Y Moy; Yong Kim; James P O'Callaghan; Li-Huei Tsai; Paul Greengard; Angus Nairn; Christopher William Cowan; Diane B Miller; Peter P Antich; James A Bibb
Striatal dysregulation of Cdk5 alters locomotor responses to cocaine, motor learning, and dendritic morphology.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(47):18561-6.
2008: Diane C Lagace; David R Benavides; Janice W Kansy; Marina Mapelli; Paul Greengard; James A Bibb; Amelia J Eisch
Cdk5 is essential for adult hippocampal neurogenesis.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(47):18567-71.
2008: Joseph P Doyle; Joseph D Dougherty; Myriam Heiman; Eric F Schmidt; Tanya R Stevens; Guojun Ma; Sujata Bupp; Prerana Shrestha; Rajiv D Shah; Martin L Doughty; Shiaoching Gong; Paul Greengard; Nathaniel Heintz
Application of a translational profiling approach for the comparative analysis of CNS cell types.
Cell 2008;135(4):749-62.
2008: Myriam Heiman; Anne Schaefer; Shiaoching Gong; Jayms D Peterson; Michelle Day; Keri E Ramsey; Mayte Suárez-Fariñas; Cordelia Schwarz; Dietrich A Stephan; Dalton Surmeier; Paul Greengard; Nathaniel Heintz
A translational profiling approach for the molecular characterization of CNS cell types.
Cell 2008;135(4):738-48.
2008: Daniel Gitler; Qing Cheng; Paul Greengard; George J Augustine
Synapsin IIa controls the reserve pool of glutamatergic synaptic vesicles.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2008;28(43):10835-43.
2008: Akinori Nishi; Mahomi Kuroiwa; Diane B Miller; James P O'Callaghan; Helen S Bateup; Takahide Shuto; Naoki Sotogaku; Takaichi Fukuda; Nathaniel Heintz; Paul Greengard; Gretchen L Snyder
Distinct roles of PDE4 and PDE10A in the regulation of cAMP/PKA signaling in the striatum.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2008;28(42):10460-71.
2008: Nassima Oumata; Karima Bettayeb; Yoan Ferandin; Luc Demange; Angela Lopez-Giral; Marie-Lorène Goddard; vassilios myrianthopoulos; Emmanuel Mikros; Marc Flajolet; Paul Greengard; Laurent Meijer; Hervé Galons
Roscovitine-derived, dual-specificity inhibitors of cyclin-dependent kinases and casein kinases 1.
Journal of medicinal chemistry 2008;51(17):5229-42.
2008: Suprabha Pulipparacharuvil; William Renthal; Carly F Hale; Makoto Taniguchi; Guanghua Xiao; Arvind Kumar; Scott J Russo; Devanjan Sikder; Colleen M Dewey; Maya M Davis; Paul Greengard; Angus Nairn; Eric J Nestler; Christopher William Cowan
Cocaine regulates MEF2 to control synaptic and behavioral plasticity.
Neuron 2008;59(4):621-33.
2008: Weixing Shen; Marc Flajolet; Paul Greengard; Dalton Surmeier
Dichotomous dopaminergic control of striatal synaptic plasticity.
Science (New York, N.Y.) 2008;321(5890):848-51.
2008: Helen Bateup; Per Svenningsson; Mahomi Kuroiwa; Shiaoching Gong; Akinori Nishi; Nathaniel Heintz; Paul Greengard
Cell type-specific regulation of DARPP-32 phosphorylation by psychostimulant and antipsychotic drugs.
Nature neuroscience 2008;11(8):932-9.
2008: E Chris Muly; Angus Nairn; Paul Greengard; Don Rainnie
Subcellular distribution of the Rho-GEF Lfc in primate prefrontal cortex: effect of neuronal activation.
The Journal of comparative neurology 2008;508(6):927-39.
2008: Alexandre Stipanovich; Emmanuel Valjent; Miriam Matamales; Akinori Nishi; Jung-Hyuck Ahn; Matthieu Maroteaux; Jesus Bertran-Gonzalez; Karen Brami-Cherrier; hervé enslen; Anne-Gaëlle Corbillé; Odile Filhol; Angus Nairn; Paul Greengard; Denis Hervé; Jean-Antoine Girault
A phosphatase cascade by which rewarding stimuli control nucleosomal response.
Nature 2008;453(7197):879-84.
2008: Gerard J O'Sullivan; Mark Dunleavy; Kerstin Hakansson; Mario Clementi; Anthony Kinsella; David T Croke; John Drago; Allen Fienberg; Paul Greengard; David R Sibley; Gilberto Fisone; David C Henshall; John L Waddington
Dopamine D1 vs D5 receptor-dependent induction of seizures in relation to DARPP-32, ERK1/2 and GluR1-AMPA signalling.
Neuropharmacology 2008;54(7):1051-61.
2008: Joanna J Charlton; Patrick B Allen; Kassi Psifogeorgou; Sumana Chakravarty; Ivone Gomes; Rachael L Neve; Lakshmi A Devi; Paul Greengard; Eric J Nestler; Venetia Zachariou
Multiple actions of spinophilin regulate mu opioid receptor function.
Neuron 2008;58(2):238-47.
2008: Hung-Teh Kao; Ping Li; Helen M Chao; Stephen Janoschka; Kara Pham; Jian Feng; Bruce McEwen; Paul Greengard; Vincent A Pieribone; Barbara Porton
Early involvement of synapsin III in neural progenitor cell development in the adult hippocampus.
The Journal of comparative neurology 2008;507(6):1860-70.
2008: Jee Young Sung; Olivia Engmann; Merilee A Teylan; Angus Nairn; Paul Greengard; Yong Kim
WAVE1 controls neuronal activity-induced mitochondrial distribution in dendritic spines.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(8):3112-6.
2008: Xiaoqun Zhang; Per E Andren; Paul Greengard; Per Svenningsson
Evidence for a role of the 5-HT1B receptor and its adaptor protein, p11, in L-DOPA treatment of an animal model of Parkinsonism.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(6):2163-8.
2008: Anders Borgkvist; Daniel Marcellino; Kjell Fuxe; Paul Greengard; Gilberto Fisone
Regulation of DARPP-32 phosphorylation by Delta9-tetrahydrocannabinol.
Neuropharmacology 2008;54(1):31-5.
2007: Paolo Emilio Barbano; Marina Spivak; Marc Flajolet; Angus Nairn; Paul Greengard; Leslie Greengard
A mathematical tool for exploring the dynamics of biological networks.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(49):19169-74.
2007: Per Svenningsson; Helen Bateup; Hongshi Qi; Kogo Takamiya; Richard Huganir; Michael Spedding; Bryan L Roth; Bruce S McEwen; Paul Greengard
Involvement of AMPA receptor phosphorylation in antidepressant actions with special reference to tianeptine.
The European journal of neuroscience 2007;26(12):3509-17.
2007: Shiho Kitaoka; Tomoyuki Furuyashiki; Akinori Nishi; Takahide Shuto; Sho Koyasu; Toshiyuki Matsuoka; Masayuki Miyasaka; Paul Greengard; Shuh Narumiya
Prostaglandin E2 acts on EP1 receptor and amplifies both dopamine D1 and D2 receptor signaling in the striatum.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2007;27(47):12900-7.
2007: Anders Borgkvist; Alessandro Usiello; Paul Greengard; Gilberto Fisone
Activation of the cAMP/PKA/DARPP-32 signaling pathway is required for morphine psychomotor stimulation but not for morphine reward.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2007;32(9):1995-2003.
2007: Anne Schaefer; Dónal O'Carroll; Chan Lek Tan; Dean Hillman; Mutsuyuki Sugimori; Rodolfo R Llinas; Paul Greengard
Cerebellar neurodegeneration in the absence of microRNAs.
The Journal of experimental medicine 2007;204(7):1553-8.
2007: Ammar H Hawasli; David R Benavides; Chan Nguyen; Janice W Kansy; Kanehiro Hayashi; Pierre Chambon; Paul Greengard; Craig M Powell; Donald C Cooper; James A Bibb
Cyclin-dependent kinase 5 governs learning and synaptic plasticity via control of NMDAR degradation.
Nature neuroscience 2007;10(7):880-6.
2007: Emanuela Santini; Emmanuel Valjent; Alessandro Usiello; Mario Carta; Anders Borgkvist; Jean-Antoine Girault; Denis Hervé; Paul Greengard; Gilberto Fisone
Critical involvement of cAMP/DARPP-32 and extracellular signal-regulated protein kinase signaling in L-DOPA-induced dyskinesia.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2007;27(26):6995-7005.
2007: Léa Siksou; Philippe Rostaing; Jean-Pierre Lechaire; Thomas Boudier; Toshihisa Ohtsuka; Anna Fejtová; Hung-Teh Kao; Paul Greengard; Eckart D Gundelfinger; Antoine Triller; Serge Marty
Three-dimensional architecture of presynaptic terminal cytomatrix.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2007;27(26):6868-77.
2007: Xinhua Wang; Weizhong Zeng; Min Seuk Kim; Patrick B Allen; Paul Greengard; Shmuel Muallem
Spinophilin/neurabin reciprocally regulate signaling intensity by G protein-coupled receptors.
The EMBO journal 2007;26(11):2768-76.
2007: Jung-Hyuck Ahn; Jee Young Sung; Thomas McAvoy; Akinori Nishi; Veerle Janssens; Jozef Goris; Paul Greengard; Angus Nairn
The B''/PR72 subunit mediates Ca2+-dependent dephosphorylation of DARPP-32 by protein phosphatase 2A.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(23):9876-81.
2007: Wenjie Luo; Fei Dou; Anna Rodina; Sophorn Chip; Joungnam Kim; Qi Zhao; Kamalika Moulick; Julia Aguirre; Nian Wu; Paul Greengard; Gabriela Chiosis
Roles of heat-shock protein 90 in maintaining and facilitating the neurodegenerative phenotype in tauopathies.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(22):9511-6.
2007: Charlotte Sahlin; Anna Lord; Kristina Magnusson; Hillevi Englund; Claudia Almeida; Paul Greengard; Fred Nyberg; Gunnar K Gouras; Lars Lannfelt; Lars N G Nilsson
The Arctic Alzheimer mutation favors intracellular amyloid-beta production by making amyloid precursor protein less available to alpha-secretase.
Journal of neurochemistry 2007;101(3):854-62.
2007: Per Svenningsson; Eleni T Tzavara; Hongshi Qi; Robert Carruthers; Jeffrey M Witkin; George Nomikos; Paul Greengard
Biochemical and behavioral evidence for antidepressant-like effects of 5-HT6 receptor stimulation.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2007;27(15):4201-9.
2007: Marc Flajolet; Gen He; Myriam Heiman; Angie Lin; Angus Nairn; Paul Greengard
Regulation of Alzheimer's disease amyloid-beta formation by casein kinase I.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(10):4159-64.
2007: Jung-Hyuck Ahn; Thomas McAvoy; Sergey V Rakhilin; Akinori Nishi; Paul Greengard; Angus Nairn
Protein kinase A activates protein phosphatase 2A by phosphorylation of the B56delta subunit.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(8):2979-84.
2007: Per Svenningsson; Paul Greengard
p11 (S100A10)--an inducible adaptor protein that modulates neuronal functions.
Current opinion in pharmacology 2007;7(1):27-32.
2006: Christian Hansen; Paul Greengard; Angus Nairn; Tommy Andersson; Wolfgang F Vogel
Phosphorylation of DARPP-32 regulates breast cancer cell migration downstream of the receptor tyrosine kinase DDR1.
Experimental cell research 2006;312(20):4011-8.
2006: Wenhua Liu; Eunice Y Yuen; Patrick B Allen; Jian Feng; Paul Greengard; Zhen Yan
Adrenergic modulation of NMDA receptors in prefrontal cortex is differentially regulated by RGS proteins and spinophilin.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(48):18338-43.
2006: Anita Aperia; Paul Greengard
Dopamine receptor response to NMDA stimulation.
The American journal of psychiatry 2006;163(10):1682.
2006: Lisa A Ehrman; Michael T Williams; Tori L Schaefer; Gary A Gudelsky; Tracy M Reed; Allen Fienberg; Paul Greengard; Charles V Vorhees
Phosphodiesterase 1B differentially modulates the effects of methamphetamine on locomotor activity and spatial learning through DARPP32-dependent pathways: evidence from PDE1B-DARPP32 double-knockout mice.
Genes, brain, and behavior 2006;5(7):540-51.
2006: Lily Yan; Jessica M Bobula; Per Svenningsson; Paul Greengard; Rae Silver
DARPP-32 involvement in the photic pathway of the circadian system.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2006;26(37):9434-8.
2006: Yong Kim; Jee Young Sung; Ilaria Ceglia; Ko-Woon Lee; Jung-Hyuck Ahn; Jonathan M Halford; Amie M Kim; Seung P Kwak; Jong Bae Park; Sung Ho Ryu; Annette Schenck; Barbara Bardoni; John D Scott; Angus Nairn; Paul Greengard
Phosphorylation of WAVE1 regulates actin polymerization and dendritic spine morphology.
Nature 2006;442(7104):814-7.
2006: Kenichi Yabuuchi; M Kuroiwa; Takahide Shuto; Naoki Sotogaku; G L Snyder; Hideho Higashi; Masatoshi Tanaka; Paul Greengard; Akinori Nishi
Role of adenosine A1 receptors in the modulation of dopamine D1 and adenosine A2A receptor signaling in the neostriatum.
Neuroscience 2006;141(1):19-25.
2006: Patrick B Allen; Venetia Zachariou; Per Svenningsson; A C Lepore; D Centonze; C Costa; S Rossi; G Bender; G Chen; J Feng; G L Snyder; Giorgio Bernardi; Eric J Nestler; Z Yan; Peter A Calabresi; Paul Greengard
Distinct roles for spinophilin and neurabin in dopamine-mediated plasticity.
Neuroscience 2006;140(3):897-911.
2006: B Jill Venton; Andrew T Seipel; Paul E M Phillips; William C Wetsel; Daniel Gitler; Paul Greengard; George J Augustine; R Mark Wightman
Cocaine increases dopamine release by mobilization of a synapsin-dependent reserve pool.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2006;26(12):3206-9.
2006: Jessica P Rogers; Albert E. Beuscher; Marc Flajolet; Thomas McAvoy; Angus Nairn; Arthur J Olson; Paul Greengard
Discovery of protein phosphatase 2C inhibitors by virtual screening.
Journal of medicinal chemistry 2006;49(5):1658-67.
2006: Yong Zhang; Per Svenningsson; Roberto Picetti; Stefan D Schlussman; Angus Nairn; Ann Ho; Paul Greengard; Mary Jeanne Kreek
Cocaine self-administration in mice is inversely related to phosphorylation at Thr34 (protein kinase A site) and Ser130 (kinase CK1 site) of DARPP-32.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2006;26(10):2645-51.
2006: Venetia Zachariou; Véronique Sgambato-Faure; Teresa Sasaki; Per Svenningsson; Olivier Berton; Allen Fienberg; Angus Nairn; Paul Greengard; Eric J Nestler
Phosphorylation of DARPP-32 at Threonine-34 is required for cocaine action.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2006;31(3):555-62.
2006: Ko-Woon Lee; Yong Kim; Amie M Kim; Kathryn Helmin; Angus Nairn; Paul Greengard
Cocaine-induced dendritic spine formation in D1 and D2 dopamine receptor-containing medium spiny neurons in nucleus accumbens.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(9):3399-404.
2006: Dongming Cai; William Netzer; Minghao Zhong; Yixin Lin; Guangwei Du; Michael Frohman; David A Foster; Sangram S Sisodia; Huaxi Xu; Fred S Gorelick; Paul Greengard
Presenilin-1 uses phospholipase D1 as a negative regulator of beta-amyloid formation.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(6):1941-6.
2006: Dongming Cai; Minghao Zhong; Runsheng Wang; William Netzer; Dennis Shields; Hui Zheng; Sangram S Sisodia; David A Foster; Fred S Gorelick; Huaxi Xu; Paul Greengard
Phospholipase D1 corrects impaired betaAPP trafficking and neurite outgrowth in familial Alzheimer's disease-linked presenilin-1 mutant neurons.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(6):1936-40.
2006: Lena Scott; Sergey Zelenin; Seth Malmersjö; Jacob M Kowalewski; Eivor Zettergren Markus; Angus Nairn; Paul Greengard; hjalmar brismar; Anita Aperia
Allosteric changes of the NMDA receptor trap diffusible dopamine 1 receptors in spines.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(3):762-7.
2006: Per Svenningsson; Karima Chergui; Ilan Rachleff; Marc Flajolet; Xiaoqun Zhang; Malika El Yacoubi; Jean-Marie Vaugeois; George Nomikos; Paul Greengard
Alterations in 5-HT1B receptor function by p11 in depression-like states.
Science (New York, N.Y.) 2006;311(5757):77-80.
2006: Kerstin Håkansson; Stacey Galdi; Joseph Hendrick; Gretchen L Snyder; Paul Greengard; Gilberto Fisone
Regulation of phosphorylation of the GluR1 AMPA receptor by dopamine D2 receptors.
Journal of neurochemistry 2006;96(2):482-8.
2005: Mi Jin; Helen Bateup; Júlio C Padovan; Paul Greengard; Angus Nairn; Brian T Chait
Quantitative analysis of protein phosphorylation in mouse brain by hypothesis-driven multistage mass spectrometry.
Analytical chemistry 2005;77(24):7845-51.
2005: Ken Uematsu; Marie Futter; Linda C Hsieh-Wilson; Hideho Higashi; Hisao Maeda; Angus Nairn; Paul Greengard; Akinori Nishi
Regulation of spinophilin Ser94 phosphorylation in neostriatal neurons involves both DARPP-32-dependent and independent pathways.
Journal of neurochemistry 2005;95(6):1642-52.
2005: Jill R Bordelon; Yoland Smith; Angus Nairn; Roger J Colbran; Paul Greengard; E Chris Muly
Differential localization of protein phosphatase-1alpha, beta and gamma1 isoforms in primate prefrontal cortex.
Cerebral cortex (New York, N.Y. : 1991) 2005;15(12):1928-37.
2005: Claudia Almeida; Davide Tampellini; Reisuke H Takahashi; Paul Greengard; Michael T Lin; Eric M Snyder; Gunnar K Gouras
Beta-amyloid accumulation in APP mutant neurons reduces PSD-95 and GluR1 in synapses.
Neurobiology of disease 2005;20(2):187-98.
2005: Miho Hamada; Joseph P Hendrick; Gregory R Ryan; Mahomi Kuroiwa; Hideho Higashi; Masatoshi Tanaka; Angus Nairn; Paul Greengard; Akinori Nishi
Nicotine regulates DARPP-32 (dopamine- and cAMP-regulated phosphoprotein of 32 kDa) phosphorylation at multiple sites in neostriatal neurons.
The Journal of pharmacology and experimental therapeutics 2005;315(2):872-8.
2005: Mikael Andersson; Alessandro Usiello; Anders Borgkvist; Laura Pozzi; Cecilia Dominguez; Allen Fienberg; Per Svenningsson; Bertil B. Fredholm; Emiliana Borrelli; Paul Greengard; Gilberto Fisone
Cannabinoid action depends on phosphorylation of dopamine- and cAMP-regulated phosphoprotein of 32 kDa at the protein kinase A site in striatal projection neurons.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2005;25(37):8432-8.
2005: Eric M Snyder; Yi Nong; Claudia Almeida; Surojit Paul; Timothy Moran; Eun Young Choi; Angus Nairn; Michael W Salter; Paul J Lombroso; Gunnar K Gouras; Paul Greengard
Regulation of NMDA receptor trafficking by amyloid-beta.
Nature neuroscience 2005;8(8):1051-8.
2005: Karima Chergui; Per Svenningsson; Paul Greengard
Physiological role for casein kinase 1 in glutamatergic synaptic transmission.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2005;25(28):6601-9.
2005: Xiaozhou P Ryan; Jacqueline Alldritt; Per Svenningsson; Patrick B Allen; Gang-Yi Wu; Angus Nairn; Paul Greengard
The Rho-specific GEF Lfc interacts with neurabin and spinophilin to regulate dendritic spine morphology.
Neuron 2005;47(1):85-100.
2005: Charlotte Stenh; Hillevi Englund; Anna Lord; Ann-Sofi Johansson; Claudia Almeida; Pär Gellerfors; Paul Greengard; Gunnar K Gouras; Lars Lannfelt; Lars N G Nilsson
Amyloid-beta oligomers are inefficiently measured by enzyme-linked immunosorbent assay.
Annals of neurology 2005;58(1):147-50.
2005: Ashley E Brady; Qin Wang; Patrick B Allen; Mark A Rizzo; Paul Greengard; Lee E Limbird
Alpha 2-adrenergic agonist enrichment of spinophilin at the cell surface involves beta gamma subunits of Gi proteins and is preferentially induced by the alpha 2A-subtype.
Molecular pharmacology 2005;67(5):1690-6.
2005: Xinhua Wang; Weizhong Zeng; Abigail A Soyombo; Wei Tang; Elliott M Ross; Anthony P Barnes; Sharon L Milgram; Josef M Penninger; Patrick B Allen; Paul Greengard; Shmuel Muallem
Spinophilin regulates Ca2+ signalling by binding the N-terminal domain of RGS2 and the third intracellular loop of G-protein-coupled receptors.
Nature cell biology 2005;7(4):405-11.
2005: Sabine Hilfiker; Fabio Benfenati; Frédéric Doussau; Angus Nairn; Andrew J Czernik; George J Augustine; Paul Greengard
Structural domains involved in the regulation of transmitter release by synapsins.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2005;25(10):2658-69.
2005: Marie Futter; Ken Uematsu; Stewart A Bullock; Yong Kim; Hugh C Hemmings; Akinori Nishi; Paul Greengard; Angus Nairn
Phosphorylation of spinophilin by ERK and cyclin-dependent PK 5 (Cdk5).
Proceedings of the National Academy of Sciences of the United States of America 2005;102(9):3489-94.
2005: Satoru Takahashi; Toshio Ohshima; Andrew Cho; Taduru Sreenath; Michael Iadarola; Varsha Shukla; Yong Kim; Angus Nairn; Roscoe O Brady; Paul Greengard; Ashok Kulkarni
Increased activity of cyclin-dependent kinase 5 leads to attenuation of cocaine-mediated dopamine signaling.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(5):1737-42.
2005: Akinori Nishi; Yasuo Watanabe; Hideho Higashi; Masatoshi Tanaka; Angus Nairn; Paul Greengard
Glutamate regulation of DARPP-32 phosphorylation in neostriatal neurons involves activation of multiple signaling cascades.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(4):1199-204.
2005: Emmanuel Valjent; Vincent Pascoli; Per Svenningsson; Surojit Paul; hervé enslen; Jean-Christophe Corvol; Alexandre Stipanovich; Jocelyne Caboche; Paul J Lombroso; Angus Nairn; Paul Greengard; Denis Hervé; Jean-Antoine Girault
Regulation of a protein phosphatase cascade allows convergent dopamine and glutamate signals to activate ERK in the striatum.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(2):491-6.
2005: Per Svenningsson; Angus Nairn; Paul Greengard
DARPP-32 mediates the actions of multiple drugs of abuse.
The AAPS journal 2005;7(2):E353-60.
2004: Daniel Gitler; Yoshiko Takagishi; Jian Feng; Yong Ren; Ramona M Rodriguiz; William C Wetsel; Paul Greengard; George J Augustine
Different presynaptic roles of synapsins at excitatory and inhibitory synapses.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2004;24(50):11368-80.
2004: E Chris Muly; Patrick Allen; Maney Mazloom; Zina Aranbayeva; Audrey T Greenfield; Paul Greengard
Subcellular distribution of neurabin immunolabeling in primate prefrontal cortex: comparison with spinophilin.
Cerebral cortex (New York, N.Y. : 1991) 2004;14(12):1398-407.
2004: Charles C Ouimet; István Katona; Patrick Allen; Tamás F Freund; Paul Greengard
Cellular and subcellular distribution of spinophilin, a PP1 regulatory protein that bundles F-actin in dendritic spines.
The Journal of comparative neurology 2004;479(4):374-88.
2004: Sergey V Rakhilin; Patricia A Olson; Akinori Nishi; N N Starkova; Allen Fienberg; Angus Nairn; Dalton Surmeier; Paul Greengard
A network of control mediated by regulator of calcium/calmodulin-dependent signaling.
Science (New York, N.Y.) 2004;306(5696):698-701.
2004: Silvia Giovedì; François Darchen; Flavia Valtorta; Paul Greengard; Fabio Benfenati
Synapsin is a novel Rab3 effector protein on small synaptic vesicles. II. Functional effects of the Rab3A-synapsin I interaction.
The Journal of biological chemistry 2004;279(42):43769-79.
2004: Silvia Giovedì; Paola Vaccaro; Flavia Valtorta; François Darchen; Paul Greengard; Gianni Cesareni; Fabio Benfenati
Synapsin is a novel Rab3 effector protein on small synaptic vesicles. I. Identification and characterization of the synapsin I-Rab3 interactions in vitro and in intact nerve terminals.
The Journal of biological chemistry 2004;279(42):43760-8.
2004: Hong Wang; Wen-jie Luo; Yun-Wu Zhang; Yueming Li; Gopal Thinakaran; Paul Greengard; Huaxi Xu
Presenilins and gamma-secretase inhibitors affect intracellular trafficking and cell surface localization of the gamma-secretase complex components.
The Journal of biological chemistry 2004;279(39):40560-6.
2004: Laurent Meijer; Marc Flajolet; Paul Greengard
Pharmacological inhibitors of glycogen synthase kinase 3.
Trends in pharmacological sciences 2004;25(9):471-80.
2004: Artur Mayerhofer; S Fritz; S Mani; T Rajendra Kumar; Andrea Thalhammer; P Ingrassia; Allen Fienberg; Paul Greengard
Ovarian function and morphology after deletion of the DARPP-32 gene in mice.
Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 2004;112(8):451-7.
2004: Miho Hamada; Hideho Higashi; Angus Nairn; Paul Greengard; Akinori Nishi
Differential regulation of dopamine D1 and D2 signaling by nicotine in neostriatal neurons.
Journal of neurochemistry 2004;90(5):1094-103.
2004: Rachel E Nally; Anthony Kinsella; Orna Tighe; David T Croke; Allen Fienberg; Paul Greengard; John L Waddington
Ethologically based resolution of D2-like dopamine receptor agonist-versus antagonist-induced behavioral topography in dopamine- and adenosine 3',5'-monophosphate-regulated phosphoprotein of 32 kDa "knockout" mutants congenic on the C57BL/6 genetic background.
The Journal of pharmacology and experimental therapeutics 2004;310(3):1281-7.
2004: Stacie D Grossman; Marie Futter; Gretchen L Snyder; Patrick B Allen; Angus Nairn; Paul Greengard; Linda C Hsieh-Wilson
Spinophilin is phosphorylated by Ca2+/calmodulin-dependent protein kinase II resulting in regulation of its binding to F-actin.
Journal of neurochemistry 2004;90(2):317-24.
2004: Qin Wang; Jiali Zhao; Ashley E Brady; Jian Feng; Patrick B Allen; Robert J Lefkowitz; Paul Greengard; Lee E Limbird
Spinophilin blocks arrestin actions in vitro and in vivo at G protein-coupled receptors.
Science (New York, N.Y.) 2004;304(5679):1940-4.
2004: Marie Knockaert; Marc Blondel; Stéphane Bach; Maryse Leost; Cem Elbi; Gordon L Hager; Scott R Nagy; Dalho Han; Michael Denison; Martine Ffrench; Xiaozhou P Ryan; Prokopios Magiatis; Panagiotis Polychronopoulos; Paul Greengard; Leandros Skaltsounis; Laurent Meijer
Independent actions on cyclin-dependent kinases and aryl hydrocarbon receptor mediate the antiproliferative effects of indirubins.
Oncogene 2004;23(25):4400-12.
2004: Patrick B Allen; Audrey T Greenfield; Per Svenningsson; Derek C Haspeslagh; Paul Greengard
Phactrs 1-4: A family of protein phosphatase 1 and actin regulatory proteins.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(18):7187-92.
2004: Jean-Antoine Girault; Paul Greengard
The neurobiology of dopamine signaling.
Archives of neurology 2004;61(5):641-4.
2004: Daniel Gitler; Yimei Xu; Hung-Teh Kao; Dayu Lin; Sangmi Lim; Jian Feng; Paul Greengard; George J Augustine
Molecular determinants of synapsin targeting to presynaptic terminals.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2004;24(14):3711-20.
2004: Ta-Hsien Lin; Yi-Choang Huang; Mei-ling Chin; Yi-chen Chen; Hao-Hsuan Jeng; Fang-Min Lin; Ming-Shi Shiao; Atsuko Horiuchi; Paul Greengard; Angus Nairn; Hsien-Bin Huang
1H, 15N, and 13C resonance assignments of DARPP-32 (dopamine and cAMP-regulated phosphoprotein, Mr. 32,000)--a protein inhibitor of protein phosphatase-1.
Journal of biomolecular NMR 2004;28(4):413-4.
2004: Guojun Chen; Paul Greengard; Zhen Yan
Potentiation of NMDA receptor currents by dopamine D1 receptors in prefrontal cortex.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(8):2596-600.
2004: Karima Chergui; Per Svenningsson; Paul Greengard
Cyclin-dependent kinase 5 regulates dopaminergic and glutamatergic transmission in the striatum.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(7):2191-6.
2004: Chenjian Li; Wayne G Brake; Russell D Romeo; John C Dunlop; Marisa Gordon; Rodica Buzescu; Ana Maria Magarinos; Patrick B Allen; Paul Greengard; Victoria N Luine; Bruce S McEwen
Estrogen alters hippocampal dendritic spine shape and enhances synaptic protein immunoreactivity and spatial memory in female mice.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(7):2185-90.
2004: Panagiotis Polychronopoulos; Prokopios Magiatis; Alexios-Leandros Skaltsounis; vassilios myrianthopoulos; Emmanuel Mikros; Aldo Tarricone; Andrea Musacchio; S Mark Roe; Laurence H Pearl; Maryse Leost; Paul Greengard; Laurent Meijer
Structural basis for the synthesis of indirubins as potent and selective inhibitors of glycogen synthase kinase-3 and cyclin-dependent kinases.
Journal of medicinal chemistry 2004;47(4):935-46.
2004: E Chris Muly; Yoland Smith; Patrick Allen; Paul Greengard
Subcellular distribution of spinophilin immunolabeling in primate prefrontal cortex: localization to and within dendritic spines.
The Journal of comparative neurology 2004;469(2):185-97.
2004: Yong Tang; william janssen; Jiandong Hao; Jeffrey A Roberts; Heather McKay; Bill Lasley; Patrick B Allen; Paul Greengard; Peter R Rapp; Jeffrey Kordower; Patrick R Hof; John H Morrison
Estrogen replacement increases spinophilin-immunoreactive spine number in the prefrontal cortex of female rhesus monkeys.
Cerebral cortex (New York, N.Y. : 1991) 2004;14(2):215-23.
2004: Angus Nairn; Per Svenningsson; Akinori Nishi; Gilberto Fisone; Jean-Antoine Girault; Paul Greengard
The role of DARPP-32 in the actions of drugs of abuse.
Neuropharmacology 2004;47 Suppl 1():14-23.
2004: S J Lee; Russell D Romeo; P Svenningsson; C R Campomanes; Patrick B Allen; Paul Greengard; Bruce S McEwen
Estradiol affects spinophilin protein differently in gonadectomized males and females.
Neuroscience 2004;127(4):983-8.
2004: Per Svenningsson; Akinori Nishi; Gilberto Fisone; Jean-Antoine Girault; Angus Nairn; Paul Greengard
DARPP-32: an integrator of neurotransmission.
Annual review of pharmacology and toxicology 2004;44():269-96.
2004: Noboru Sato; Laurent Meijer; Leandros Skaltsounis; Paul Greengard; Ali H Brivanlou
Maintenance of pluripotency in human and mouse embryonic stem cells through activation of Wnt signaling by a pharmacological GSK-3-specific inhibitor.
Nature medicine 2004;10(1):55-63.
2003: Marc Flajolet; Sergey V Rakhilin; Hong Wang; Natalia Starkova; Nina Nuangchamnong; Angus Nairn; Paul Greengard
Protein phosphatase 2C binds selectively to and dephosphorylates metabotropic glutamate receptor 3.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(26):16006-11.
2003: Ryuichi Fukui; Per Svenningsson; Toyojiro Matsuishi; Hideho Higashi; Angus Nairn; Paul Greengard; Akinori Nishi
Effect of methylphenidate on dopamine/DARPP signalling in adult, but not young, mice.
Journal of neurochemistry 2003;87(6):1391-401.
2003: Laurent Meijer; Alexios-Leandros Skaltsounis; Prokopios Magiatis; Panagiotis Polychronopoulos; Marie Knockaert; Maryse Leost; Xiaozhou P Ryan; Claudia Alin Vonica; Ali H Brivanlou; Rana Dajani; Claudia Crovace; Cataldo Tarricone; Andrea Musacchio; S Mark Roe; Laurence H Pearl; Paul Greengard
GSK-3-selective inhibitors derived from Tyrian purple indirubins.
Chemistry & biology 2003;10(12):1255-66.
2003: Rachel E Nally; Fergal N McNamara; Jeremiah J Clifford; Anthony Kinsella; Orna Tighe; David T Croke; Allen Fienberg; Paul Greengard; John L Waddington
Topographical Assessment of Ethological and Dopamine Receptor Agonist-Induced Behavioral Phenotype in Mutants with Congenic DARPP-32 'Knockout'.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2003;28(12):2055-63.
2003: Per Svenningsson; Eleni T Tzavara; Robert Carruthers; Ilan Rachleff; Sigrid Wattler; Michael Nehls; David L McKinzie; Allen Fienberg; George Nomikos; Paul Greengard
Diverse psychotomimetics act through a common signaling pathway.
Science (New York, N.Y.) 2003;302(5649):1412-5.
2003: Gretchen L Snyder; Stacey Galdi; Allen Fienberg; Patrick Allen; Angus Nairn; Paul Greengard
Regulation of AMPA receptor dephosphorylation by glutamate receptor agonists.
Neuropharmacology 2003;45(6):703-13.
2003: Jiandong Hao; william janssen; Yong Tang; Jeffrey A Roberts; Heather McKay; Bill Lasley; Patrick B Allen; Paul Greengard; Peter R Rapp; Jeffrey Kordower; Patrick R Hof; John H Morrison
Estrogen increases the number of spinophilin-immunoreactive spines in the hippocampus of young and aged female rhesus monkeys.
The Journal of comparative neurology 2003;465(4):540-50.
2003: William Netzer; Fei Dou; Dongming Cai; Darren R Veach; Stephanie Jean; Yueming Li; William G Bornmann; Bayard Clarkson; Huaxi Xu; Paul Greengard
Gleevec inhibits beta-amyloid production but not Notch cleavage.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(21):12444-9.
2003: Ashley E Brady; Qin Wang; Roger J Colbran; Patrick B Allen; Paul Greengard; Lee E Limbird
Spinophilin stabilizes cell surface expression of alpha 2B-adrenergic receptors.
The Journal of biological chemistry 2003;278(34):32405-12.
2003: Shasta Sabo; Annat F Ikin; Joseph Buxbaum; Paul Greengard
The amyloid precursor protein and its regulatory protein, FE65, in growth cones and synapses in vitro and in vivo.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2003;23(13):5407-15.
2003: Laura Pozzi; Kerstin Håkansson; Alessandro Usiello; Anders Borgkvist; Maria Lindskog; Paul Greengard; Gilberto Fisone
Opposite regulation by typical and atypical anti-psychotics of ERK1/2, CREB and Elk-1 phosphorylation in mouse dorsal striatum.
Journal of neurochemistry 2003;86(2):451-9.
2003: Ona Bloom; Emma Evergren; Nikolai Tomilin; Ole Kjaerulff; Peter Löw; Lennart Brodin; Vincent A Pieribone; Paul Greengard; Oleg Shupliakov
Colocalization of synapsin and actin during synaptic vesicle recycling.
The Journal of cell biology 2003;161(4):737-47.
2003: Barbara Picconi; Diego Centonze; Kerstin Håkansson; Giorgio Bernardi; Paul Greengard; Gilberto Fisone; M Angela Cenci; Paolo Calabresi
Loss of bidirectional striatal synaptic plasticity in L-DOPA-induced dyskinesia.
Nature neuroscience 2003;6(5):501-6.
2003: Young-Mi Kim; Takuo Watanabe; Patrick B Allen; Young-Myoung Kim; Shin-Jeong Lee; Paul Greengard; Angus Nairn; Young-Guen Kwon
PNUTS, a protein phosphatase 1 (PP1) nuclear targeting subunit. Characterization of its PP1- and RNA-binding domains and regulation by phosphorylation.
The Journal of biological chemistry 2003;278(16):13819-28.
2003: Ping Chi; Paul Greengard; Timothy A Ryan
Synaptic vesicle mobilization is regulated by distinct synapsin I phosphorylation pathways at different frequencies.
Neuron 2003;38(1):69-78.
2003: Niklas Lindgren; Alessandro Usiello; Michel Goiny; John W Haycock; Eric Erbs; Paul Greengard; Tomas Hokfelt; Emiliana Borrelli; Gilberto Fisone
Distinct roles of dopamine D2L and D2S receptor isoforms in the regulation of protein phosphorylation at presynaptic and postsynaptic sites.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(7):4305-9.
2003: Akinori Nishi; Feng Liu; Seiichiro Matsuyama; Miho Hamada; Hideho Higashi; Angus Nairn; Paul Greengard
Metabotropic mGlu5 receptors regulate adenosine A2A receptor signaling.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(3):1322-7.
2003: Maria Sol Kruse; Shinsuke Adachi; Lena Scott; Ulla Holtbäck; Paul Greengard; Anita Aperia; hjalmar brismar
Recruitment of renal dopamine 1 receptors requires an intact microtubulin network.
Pflügers Archiv : European journal of physiology 2003;445(5):534-9.
2003: Dongming Cai; Jae Yoon Leem; Jeffrey P Greenfield; Pei Wang; Benny S Kim; Runsheng Wang; Kryslaine O Lopes; Seong-Hun Kim; Hui Zheng; Paul Greengard; Sangram S Sisodia; Gopal Thinakaran; Huaxi Xu
Presenilin-1 regulates intracellular trafficking and cell surface delivery of beta-amyloid precursor protein.
The Journal of biological chemistry 2003;278(5):3446-54.
2003: Fei Dou; William Netzer; Kentaro Tanemura; Feng Li; F Ulrich Hartl; Akihiko Takashima; Gunnar K Gouras; Paul Greengard; Huaxi Xu
Chaperones increase association of tau protein with microtubules.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(2):721-6.
2003: Linda C Hsieh-Wilson; Fabio Benfenati; Gretchen L Snyder; Patrick B Allen; Angus Nairn; Paul Greengard
Phosphorylation of spinophilin modulates its interaction with actin filaments.
The Journal of biological chemistry 2003;278(2):1186-94.
2003: Takuo Watanabe; Edgar F da Cruz e Silva; Hsien-Bin Huang; Natalia Starkova; Young-Guen Kwon; Atsuko Horiuchi; Paul Greengard; Angus Nairn
Preparation and characterization of recombinant protein phosphatase 1.
Methods in enzymology 2003;366():321-38.
2003: SD Norrholm; James A Bibb; Eric J Nestler; Charles C Ouimet; J R Taylor; Paul Greengard
Cocaine-induced proliferation of dendritic spines in nucleus accumbens is dependent on the activity of cyclin-dependent kinase-5.
Neuroscience 2003;116(1):19-22.
2003: Shogo Endo; Angus Nairn; Paul Greengard; Masao Ito
Thr123 of rat G-substrate contributes to its action as a protein phosphatase inhibitor.
Neuroscience research 2003;45(1):79-89.
2002: Vincent A Pieribone; Barbara Porton; Beatrice Rendon; Jian Feng; Paul Greengard; Hung-Teh Kao
Expression of synapsin III in nerve terminals and neurogenic regions of the adult brain.
The Journal of comparative neurology 2002;454(2):105-14.
2002: Jorge Flores-Hernández; Carlos Cepeda; Elizabeth Hernández-Echeagaray; Christopher R Calvert; Eve S Jokel; Allen Fienberg; Paul Greengard; Michael S Levine
Dopamine enhancement of NMDA currents in dissociated medium-sized striatal neurons: role of D1 receptors and DARPP-32.
Journal of neurophysiology 2002;88(6):3010-20.
2002: Feng Liu; David M Virshup; Angus Nairn; Paul Greengard
Mechanism of regulation of casein kinase I activity by group I metabotropic glutamate receptors.
The Journal of biological chemistry 2002;277(47):45393-9.
2002: Reisuke H Takahashi; Teresa A Milner; Feng Li; Ellen E Nam; Mark A Edgar; Haruyasu Yamaguchi; M Flint Beal; Huaxi Xu; Paul Greengard; Gunnar K Gouras
Intraneuronal Alzheimer abeta42 accumulates in multivesicular bodies and is associated with synaptic pathology.
The American journal of pathology 2002;161(5):1869-79.
2002: Oleg Shupliakov; Ona Bloom; Jenny Susanna Gustafsson; Ole Kjaerulff; Peter Low; Nikolai Tomilin; Vincent A Pieribone; Paul Greengard; Lennart Brodin
Impaired recycling of synaptic vesicles after acute perturbation of the presynaptic actin cytoskeleton.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(22):14476-81.
2002: Nina Irwin; Steven Chao; Luda Goritchenko; Atsuko Horiuchi; Paul Greengard; Angus Nairn; Larry I Benowitz
Nerve growth factor controls GAP-43 mRNA stability via the phosphoprotein ARPP-19.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(19):12427-31.
2002: Marie Knockaert; Paul Greengard; Laurent Meijer
Pharmacological inhibitors of cyclin-dependent kinases.
Trends in pharmacological sciences 2002;23(9):417-25.
2002: Maria Lindskog; Per Svenningsson; Laura Pozzi; Yong Kim; Allen Fienberg; James A Bibb; Bertil B. Fredholm; Angus Nairn; Paul Greengard; Gilberto Fisone
Involvement of DARPP-32 phosphorylation in the stimulant action of caffeine.
Nature 2002;418(6899):774-8.
2002: Andrea Menegon; Claudia Verderio; Chiara Leoni; Fabio Benfenati; Andrew J Czernik; Paul Greengard; Michela Matteoli; Flavia Valtorta
Spatial and temporal regulation of Ca2+/calmodulin-dependent protein kinase II activity in developing neurons.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2002;22(16):7016-26.
2002: Katherine A Albert; Hugh C Hemmings; Anna I B Adamo; Steven G Potkin; Schahram Akbarian; Curt A Sandman; Carl W Cotman; William E Bunney; Paul Greengard
Evidence for decreased DARPP-32 in the prefrontal cortex of patients with schizophrenia.
Archives of general psychiatry 2002;59(8):705-12.
2002: Stephen E Alves; Elena Hoskin; Susan J Lee; Wayne G Brake; Deveroux Ferguson; Victoria N Luine; Patrick B Allen; Paul Greengard; Bruce S McEwen
Serotonin mediates CA1 spine density but is not crucial for ovarian steroid regulation of synaptic plasticity in the adult rat dorsal hippocampus.
Synapse (New York, N.Y.) 2002;45(2):143-51.
2002: Tracy M Reed; David R Repaske; Gretchen L Snyder; Paul Greengard; Charles V Vorhees
Phosphodiesterase 1B knock-out mice exhibit exaggerated locomotor hyperactivity and DARPP-32 phosphorylation in response to dopamine agonists and display impaired spatial learning.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2002;22(12):5188-97.
2002: Laura Gasparini; William Netzer; Paul Greengard; Huaxi Xu
Does insulin dysfunction play a role in Alzheimer's disease?
Trends in pharmacological sciences 2002;23(6):288-93.
2002: Jian Feng; Ping Chi; Thomas A Blanpied; Yimei Xu; Ana Maria Magarinos; Adriana Ferreira; Reisuke H Takahashi; Hung-Teh Kao; Bruce S McEwen; Timothy A Ryan; George J Augustine; Paul Greengard
Regulation of neurotransmitter release by synapsin III.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2002;22(11):4372-80.
2002: Andrew N Carr; Albrecht G Schmidt; Yoichi Suzuki; Federica del Monte; Yoji Sato; Carita Lanner; Kristine Breeden; Shao-Ling Jing; Patrick B Allen; Paul Greengard; Atsuko Yatani; Brian D Hoit; Ingrid L Grupp; Roger J Hajjar; Anna A DePaoli-Roach; Evangelia G Kranias
Type 1 phosphatase, a negative regulator of cardiac function.
Molecular and cellular biology 2002;22(12):4124-35.
2002: Akinori Nishi; James A Bibb; Seiichiro Matsuyama; Miho Hamada; Hideho Higashi; Angus Nairn; Paul Greengard
Regulation of DARPP-32 dephosphorylation at PKA- and Cdk5-sites by NMDA and AMPA receptors: distinct roles of calcineurin and protein phosphatase-2A.
Journal of neurochemistry 2002;81(4):832-41.
2002: Zhen Yan; Ping Chi; James A Bibb; Timothy A Ryan; Paul Greengard
Roscovitine: a novel regulator of P/Q-type calcium channels and transmitter release in central neurons.
The Journal of physiology 2002;540(Pt 3):761-70.
2002: Hung-Teh Kao; Hongjun Song; Barbara Porton; Guo-Li Ming; Josephine Hoh; Michael Abraham; Andrew J Czernik; Vincent A Pieribone; Mu-ming Poo; Paul Greengard
A protein kinase A-dependent molecular switch in synapsins regulates neurite outgrowth.
Nature neuroscience 2002;5(5):431-7.
2002: Venetia Zachariou; Marianne Benoit-Marand; Patrick B Allen; Peter Ingrassia; Allen Fienberg; François Gonon; Paul Greengard; Marina R Picciotto
Reduction of cocaine place preference in mice lacking the protein phosphatase 1 inhibitors DARPP 32 or Inhibitor 1.
Biological psychiatry 2002;51(8):612-20.
2002: Jeffrey P Greenfield; Lawrence Leung; Dongming Cai; Krista Kaasik; Rachel S Gross; Enrique Rodriguez-Boulan; Paul Greengard; Huaxi Xu
Estrogen lowers Alzheimer beta-amyloid generation by stimulating trans-Golgi network vesicle biogenesis.
The Journal of biological chemistry 2002;277(14):12128-36.
2002: Seiichiro Matsuyama; Hideho Higashi; Hisao Maeda; Paul Greengard; Akinori Nishi
Neurotensin regulates DARPP-32 thr34 phosphorylation in neostriatal neurons by activation of dopamine D1-type receptors.
Journal of neurochemistry 2002;81(2):325-34.
2002: Per Svenningsson; Eleni T Tzavara; Feng Liu; Allen Fienberg; George Nomikos; Paul Greengard
DARPP-32 mediates serotonergic neurotransmission in the forebrain.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(5):3188-93.
2002: Per Svenningsson; Eleni T Tzavara; Jeffrey M Witkin; Allen Fienberg; George Nomikos; Paul Greengard
Involvement of striatal and extrastriatal DARPP-32 in biochemical and behavioral effects of fluoxetine (Prozac).
Proceedings of the National Academy of Sciences of the United States of America 2002;99(5):3182-7.
2002: Yoko Yamagata; Jasmina Jovanovic; Andrew J Czernik; Paul Greengard; Kunihiko Obata
Bidirectional changes in synapsin I phosphorylation at MAP kinase-dependent sites by acute neuronal excitation in vivo.
Journal of neurochemistry 2002;80(5):835-42.
2002: Lena Scott; Maria Sol Kruse; Hans Forssberg; hjalmar brismar; Paul Greengard; Anita Aperia
Selective up-regulation of dopamine D1 receptors in dendritic spines by NMDA receptor activation.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(3):1661-4.
2002: Stacie D Grossman; Linda C Hsieh-Wilson; Patrick B Allen; Angus Nairn; Paul Greengard
The actin-binding domain of spinophilin is necessary and sufficient for targeting to dendritic spines.
Neuromolecular medicine 2002;2(1):61-9.
2001: Ping Chi; Paul Greengard; Timothy A Ryan
Synapsin dispersion and reclustering during synaptic activity.
Nature neuroscience 2001;4(12):1187-93.
2001: E Chris Muly; Paul Greengard; Patricia S Goldman-Rakic
Distribution of protein phosphatases-1 alpha and -1 gamma 1 and the D(1) dopamine receptor in primate prefrontal cortex: Evidence for discrete populations of spines.
The Journal of comparative neurology 2001;440(3):261-70.
2001: Paul Greengard
The neurobiology of slow synaptic transmission.
Science (New York, N.Y.) 2001;294(5544):1024-30.
2001: Angus Nairn; Paul Greengard
A novel cyclin provides a link between dopamine and RNA processing.
Neuron 2001;32(2):174-6.
2001: Jasmina Jovanovic; T S Sihra; Angus Nairn; Hugh C Hemmings; Paul Greengard; Andrew J Czernik
Opposing changes in phosphorylation of specific sites in synapsin I during Ca2+-dependent glutamate release in isolated nerve terminals.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2001;21(20):7944-53.
2001: Riqiang Yan; P Han; H Miao; Paul Greengard; H Xu
The transmembrane domain of the Alzheimer's beta-secretase (BACE1) determines its late Golgi localization and access to beta -amyloid precursor protein (APP) substrate.
The Journal of biological chemistry 2001;276(39):36788-96.
2001: Feng Liu; X H Ma; Jernej Ule; James A Bibb; Akinori Nishi; A J DeMaggio; Zhen Yan; Angus Nairn; Paul Greengard
Regulation of cyclin-dependent kinase 5 and casein kinase 1 by metabotropic glutamate receptors.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(20):11062-8.
2001: C A Stafstrom-Davis; Charles C Ouimet; J Feng; P B Allen; Paul Greengard; Thomas Houpt
Impaired conditioned taste aversion learning in spinophilin knockout mice.
Learning & memory (Cold Spring Harbor, N.Y.) 2001;8(5):272-8.
2001: Ann-Christine Eklöf; Ulla Holtbäck; J Svennilson; Allen Fienberg; Paul Greengard; Anita Aperia
Increased blood pressure and loss of anp-induced natriuresis in mice lacking DARPP-32 gene.
Clinical and experimental hypertension (New York, N.Y. : 1993) 2001;23(6):449-60.
2001: Andrew N Carr; Roy L Sutliff; Craig S Weber; P B Allen; Paul Greengard; Primal De Lanerolle; Evangelia G Kranias; Richard J Paul
Is myosin phosphatase regulated in vivo by inhibitor-1? Evidence from inhibitor-1 knockout mice.
The Journal of physiology 2001;534(Pt. 2):357-66.
2001: Paolo Calabresi; Paolo Gubellini; Barbara Picconi; Diego Centonze; Antonio Pisani; Paola Bonsi; Paul Greengard; Robert A Hipskind; Emiliana Borrelli; Giorgio Bernardi
Inhibition of mitochondrial complex II induces a long-term potentiation of NMDA-mediated synaptic excitation in the striatum requiring endogenous dopamine.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2001;21(14):5110-20.
2001: Shasta Sabo; Annat F Ikin; Joseph Buxbaum; Paul Greengard
The Alzheimer amyloid precursor protein (APP) and FE65, an APP-binding protein, regulate cell movement.
The Journal of cell biology 2001;153(7):1403-14.
2001: Yann Humeau; Frédéric Doussau; F Vitiello; Paul Greengard; Fabio Benfenati; Bernard Poulain
Synapsin controls both reserve and releasable synaptic vesicle pools during neuronal activity and short-term plasticity in Aplysia.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2001;21(12):4195-206.
2001: Paul Greengard
The neurobiology of dopamine signaling.
Bioscience reports 2001;21(3):247-69.
2001: James A Bibb; Akinori Nishi; JP O'Callaghan; Jernej Ule; M Lan; Gretchen L Snyder; A Horiuchi; T Saito; Shin-ichi Hisanaga; Andrew J Czernik; Angus Nairn; Paul Greengard
Phosphorylation of protein phosphatase inhibitor-1 by Cdk5.
The Journal of biological chemistry 2001;276(17):14490-7.
2001: L Gasparini; Gunnar K Gouras; Runsheng Wang; Rachel S Gross; M Flint Beal; Paul Greengard; Huaxi Xu
Stimulation of beta-amyloid precursor protein trafficking by insulin reduces intraneuronal beta-amyloid and requires mitogen-activated protein kinase signaling.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2001;21(8):2561-70.
2001: Hsien-Bin Huang; Yi-chen Chen; Atsuko Horiuchi; Li-Huei Tsai; H T Liu; Chia-Lin Chyan; M J Hsieh; C K Liu; Fang-Min Lin; Paul Greengard; Angus Nairn; Ming-Shi Shiao; Ta-Hsien Lin
Backbone 1H, 15N, and 13C resonance assignments of ARPP-19.
Journal of biomolecular NMR 2001;19(4):383-4.
2001: I Dulubova; A Horiuchi; Gretchen L Snyder; Jean-Antoine Girault; Andrew J Czernik; L Shao; R Ramabhadran; Paul Greengard; Angus Nairn
ARPP-16/ARPP-19: a highly conserved family of cAMP-regulated phosphoproteins.
Journal of neurochemistry 2001;77(1):229-38.
2001: James A Bibb; Jiayun Chen; J R Taylor; Per Svenningsson; Akinori Nishi; Gretchen L Snyder; Zhen Yan; Z K Sagawa; Charles C Ouimet; Angus Nairn; Eric J Nestler; Paul Greengard
Effects of chronic exposure to cocaine are regulated by the neuronal protein Cdk5.
Nature 2001;410(6826):376-80.
2001: T Watanabe; HB Huang; A Horiuchi; E F da Cruze Silva; Linda C Hsieh-Wilson; Patrick B Allen; Shirish Shenolikar; Paul Greengard; Angus Nairn
Protein phosphatase 1 regulation by inhibitors and targeting subunits.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(6):3080-5.
2001: Wayne G Brake; Stephen E Alves; J C Dunlop; S J Lee; Karen Bulloch; Patrick B Allen; Paul Greengard; Bruce S McEwen
Novel target sites for estrogen action in the dorsal hippocampus: an examination of synaptic proteins.
Endocrinology 2001;142(3):1284-9.
2001: K J Arrow; Julius Axelrod; franccesca villella; P Berg; John M Bishop; N Bloembergen; Herbert C Brown; J Cibelli; S Cohen; L N Cooper; E J Corey; J W Cronin; Robert F Curl; R Dulbecco; E H Fischer; V L Fitch; Robert W Fogel; J I Friedman; R F Furchgott; M Gell-Mann; W Gilbert; A Gilman; D Glaser; S L Glashow; R M Green; Paul Greengard; Roger Guillemin; L Hayflick; Herbert A Hauptman; J J Heckman; Alan J Heeger; Dudley R Herschbach; David H Hubel; R Hulse; Eric R Kandel; Jerome Karle; L R Klein; W Kohn; A Kornberg; Edwin G Krebs; R P Lanza; R Laughlin; L Lederman; D M Lee; E Lewis; William N Lipscomb; R A Marcus; D McFadden; RB Merrifield; R Merton; F Modigliani; M J Molina; F Murad; Marshall Nirenberg; D C North; George A Olah; D Osheroff; GE Palade; M Perl; N F Ramsey; B Richter; Richard J Roberts; P A Samuelson; M Schwartz; Phillip A Sharp; Richard E Smalley; Hamilton O Smith; R M Solow; H Stormer; H Taube; R Taylor; ED Thomas; J Tobin; Susumu Tonegawa; C Townes; James D Watson; S Weinberg; T H Weller; M D West; Eric Wieschaus; Torsten N Wiesel; R W Wilson
Nobel laureates' letter to President Bush.
Washington post (Washington, D.C. : 1974) 2001;():A02.
2001: Sabine Hilfiker; Andrew J Czernik; Paul Greengard; George J Augustine
Tonically active protein kinase A regulates neurotransmitter release at the squid giant synapse.
The Journal of physiology 2001;531(Pt 1):141-6.
2001: J J Cheetham; Sabine Hilfiker; Fabio Benfenati; Thomas Weber; Paul Greengard; Andrew J Czernik
Identification of synapsin I peptides that insert into lipid membranes.
The Biochemical journal 2001;354(Pt 1):57-66.
2001: S Leclerc; M Garnier; R Hoessel; Doris Marko; James A Bibb; Gretchen L Snyder; Paul Greengard; J Biernat; Y Z Wu; Eva-Maria Mandelkow; Gerhard Eisenbrand; Laurent Meijer
Indirubins inhibit glycogen synthase kinase-3 beta and CDK5/p25, two protein kinases involved in abnormal tau phosphorylation in Alzheimer's disease. A property common to most cyclin-dependent kinase inhibitors?
The Journal of biological chemistry 2001;276(1):251-60.
2001: Michael S Lidow; Zan-Min Song; Stacy A Castner; P B Allen; Paul Greengard; Patricia S Goldman-Rakic
Antipsychotic treatment induces alterations in dendrite- and spine-associated proteins in dopamine-rich areas of the primate cerebral cortex.
Biological psychiatry 2001;49(1):1-12.
2001: Fred O Risinger; PA Freeman; Paul Greengard; Allen Fienberg
Motivational effects of ethanol in DARPP-32 knock-out mice.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2001;21(1):340-8.
2000: Paolo Calabresi; Paolo Gubellini; Diego Centonze; Barbara Picconi; Giorgio Bernardi; Karima Chergui; Per Svenningsson; Allen Fienberg; Paul Greengard
Dopamine and cAMP-regulated phosphoprotein 32 kDa controls both striatal long-term depression and long-term potentiation, opposing forms of synaptic plasticity.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2000;20(22):8443-51.
2000: Akinori Nishi; James A Bibb; Gretchen L Snyder; Hideho Higashi; Angus Nairn; Paul Greengard
Amplification of dopaminergic signaling by a positive feedback loop.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(23):12840-5.
2000: Andrea Menegon; David Dunlap; F Castano; Fabio Benfenati; Andrew J Czernik; Paul Greengard; Flavia Valtorta
Use of phosphosynapsin I-specific antibodies for image analysis of signal transduction in single nerve terminals.
Journal of cell science 2000;113 ( Pt 20)():3573-82.
2000: Maryse Leost; Christiane Schultz; Andreas Link; Y Z Wu; J Biernat; Eva-Maria Mandelkow; James A Bibb; Gretchen L Snyder; Paul Greengard; Daniel W Zaharevitz; Rick Gussio; Adrian M Senderowicz; Edward A Sausville; Conrad Kunick; Laurent Meijer
Paullones are potent inhibitors of glycogen synthase kinase-3beta and cyclin-dependent kinase 5/p25.
European journal of biochemistry / FEBS 2000;267(19):5983-94.
2000: Franco Onofri; S Giovedi; Hung-Teh Kao; Flavia Valtorta; Lucilla Bongiorno-Borbone; Pietro De Camilli; Paul Greengard; Fabio Benfenati
Specificity of the binding of synapsin I to Src homology 3 domains.
The Journal of biological chemistry 2000;275(38):29857-67.
2000: Koichi Iijima; K Ando; S Takeda; Y Satoh; T Seki; Shigeyoshi Itohara; Paul Greengard; Yutaka Kirino; Angus Nairn; Takahiro Suzuki
Neuron-specific phosphorylation of Alzheimer's beta-amyloid precursor protein by cyclin-dependent kinase 5.
Journal of neurochemistry 2000;75(3):1085-91.
2000: Hsien-Bin Huang; Yi-chen Chen; Li-Huei Tsai; H Wang; Fang-Min Lin; Atsuko Horiuchi; Paul Greengard; Angus Nairn; Ming-Shi Shiao; Ta-Hsien Lin
Backbone 1H, 15N, and 13C resonance assignments of inhibitor-2 -- a protein inhibitor of protein phosphatase-1.
Journal of biomolecular NMR 2000;17(4):359-60.
2000: Jian Feng; Zhen Yan; Adriana Ferreira; K Tomizawa; J A Liauw; Min Zhuo; Patrick B Allen; Charles C Ouimet; Paul Greengard
Spinophilin regulates the formation and function of dendritic spines.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(16):9287-92.
2000: G L Caporaso; James A Bibb; Gretchen L Snyder; C Valle; Sergey V Rakhilin; Allen Fienberg; Hugh C Hemmings; Angus Nairn; Paul Greengard
Drugs of abuse modulate the phosphorylation of ARPP-21, a cyclic AMP-regulated phosphoprotein enriched in the basal ganglia.
Neuropharmacology 2000;39(9):1637-44.
2000: Per Svenningsson; Allen Fienberg; Patrick B Allen; C L Moine; Maria Lindskog; Gilberto Fisone; Paul Greengard; Bertil B. Fredholm
Dopamine D(1) receptor-induced gene transcription is modulated by DARPP-32.
Journal of neurochemistry 2000;75(1):248-57.
2000: Gretchen L Snyder; Patrick B Allen; Allen Fienberg; C G Valle; Richard Huganir; Angus Nairn; Paul Greengard
Regulation of phosphorylation of the GluR1 AMPA receptor in the neostriatum by dopamine and psychostimulants in vivo.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2000;20(12):4480-8.
2000: Charles J Heyser; Allen Fienberg; Paul Greengard; Lisa H Gold
DARPP-32 knockout mice exhibit impaired reversal learning in a discriminated operant task.
Brain research 2000;867(1-2):122-30.
2000: James A Bibb; Zhen Yan; Per Svenningsson; Gretchen L Snyder; Vincent A Pieribone; A Horiuchi; Angus Nairn; A Messer; Paul Greengard
Severe deficiencies in dopamine signaling in presymptomatic Huntington's disease mice.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(12):6809-14.
2000: Adriana Ferreira; H T Kao; J Feng; M Rapoport; Paul Greengard
Synapsin III: developmental expression, subcellular localization, and role in axon formation.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2000;20(10):3736-44.
2000: Patrick B Allen; Oivind Hvalby; Vidar Jensen; Mick L Errington; M Ramsay; F A Chaudhry; T V P Bliss; Jon Storm-Mathisen; R G Morris; P Andersen; Paul Greengard
Protein phosphatase-1 regulation in the induction of long-term potentiation: heterogeneous molecular mechanisms.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2000;20(10):3537-43.
2000: Jorge Flores-Hernandez; S Hernandez; G L Snyder; Zhen Yan; Allen Fienberg; Stephen J Moss; Paul Greengard; Dalton Surmeier
D(1) dopamine receptor activation reduces GABA(A) receptor currents in neostriatal neurons through a PKA/DARPP-32/PP1 signaling cascade.
Journal of neurophysiology 2000;83(5):2996-3004.
2000: S Ivar Walaas; S Hilfiker; L Li; L S Chin; Paul Greengard
Decrease in phorbol ester-induced potentiation of noradrenaline release in synapsin I-deficient mice.
Synapse (New York, N.Y.) 2000;36(2):114-9.
2000: Jasmina Jovanovic; Andrew J Czernik; Allen Fienberg; Paul Greengard; T S Sihra
Synapsins as mediators of BDNF-enhanced neurotransmitter release.
Nature neuroscience 2000;3(4):323-9.
2000: J Näslund; Vahram Haroutunian; Richard C Mohs; Kenneth L Davis; Peter Davies; Paul Greengard; Joseph Buxbaum
Correlation between elevated levels of amyloid beta-peptide in the brain and cognitive decline.
JAMA : the journal of the American Medical Association 2000;283(12):1571-7.
2000: Allen Fienberg; Paul Greengard
The DARPP-32 knockout mouse.
Brain research. Brain research reviews 2000;31(2-3):313-9.
2000: Oleg Aizman; hjalmar brismar; Per Uhlén; E Zettergren; Allan Levey; Hans Forssberg; Paul Greengard; Anita Aperia
Anatomical and physiological evidence for D1 and D2 dopamine receptor colocalization in neostriatal neurons.
Nature neuroscience 2000;3(3):226-30.
2000: Per Svenningsson; Maria Lindskog; C Ledent; M Parmentier; Paul Greengard; Bertil B. Fredholm; Gilberto Fisone
Regulation of the phosphorylation of the dopamine- and cAMP-regulated phosphoprotein of 32 kDa in vivo by dopamine D1, dopamine D2, and adenosine A2A receptors.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(4):1856-60.
2000: Shaila K Mani; Allen Fienberg; JP O'Callaghan; G L Snyder; Patrick B Allen; P K Dash; A N Moore; A J Mitchell; James A Bibb; Paul Greengard; Bert W O'Malley
Requirement for DARPP-32 in progesterone-facilitated sexual receptivity in female rats and mice.
Science (New York, N.Y.) 2000;287(5455):1053-6.
2000: Gunnar K Gouras; Huaxi Xu; Rachel S Gross; Jeffrey P Greenfield; B Hai; Runsheng Wang; Paul Greengard
Testosterone reduces neuronal secretion of Alzheimer's beta-amyloid peptides.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(3):1202-5.
2000: Gunnar K Gouras; J Tsai; J Naslund; B Vincent; Mark A Edgar; F Checler; Jeffrey P Greenfield; Vahram Haroutunian; Joseph Buxbaum; Huaxi Xu; Paul Greengard; Norman Richard Relkin
Intraneuronal Abeta42 accumulation in human brain.
The American journal of pathology 2000;156(1):15-20.
1999: Hung-Teh Kao; Barbara Porton; Sabine Hilfiker; Giovanni Stefani; Vincent A Pieribone; Rob DeSalle; Paul Greengard
Molecular evolution of the synapsin gene family.
The Journal of experimental zoology 1999;285(4):360-77.
1999: James A Bibb; Gretchen L Snyder; Akinori Nishi; Zhen Yan; Laurent Meijer; Allen Fienberg; Li-Huei Tsai; Y T Kwon; Jean-Antoine Girault; Andrew J Czernik; Richard Huganir; Hugh C Hemmings; Angus Nairn; Paul Greengard
Phosphorylation of DARPP-32 by Cdk5 modulates dopamine signalling in neurons.
Nature 1999;402(6762):669-71.
1999: Barbara Porton; Hung-Teh Kao; Paul Greengard
Characterization of transcripts from the synapsin III gene locus.
Journal of neurochemistry 1999;73(6):2266-71.
1999: Jörg Heierhorst; Kenneth I Mitchelhill; RJ Mann; Tony Tiganis; A J Czernik; Paul Greengard; Bruce E Kemp
Synapsins as major neuronal Ca2+/S100A1-interacting proteins.
The Biochemical journal 1999;344 Pt 2():577-83.
1999: Jeffrey P Greenfield; Huaxi Xu; Paul Greengard; Sam Gandy; M Seeger
Generation of the amyloid-beta peptide N terminus in Saccharomyces cerevisiae expressing human Alzheimer's amyloid-beta precursor protein.
The Journal of biological chemistry 1999;274(48):33843-6.
1999: Akinori Nishi; Gilberto Fisone; Gretchen L Snyder; I Dulubova; Anita Aperia; Angus Nairn; Paul Greengard
Regulation of Na+, K+-ATPase isoforms in rat neostriatum by dopamine and protein kinase C.
Journal of neurochemistry 1999;73(4):1492-501.
1999: T McAvoy; P B Allen; H Obaishi; H Nakanishi; Y Takai; Paul Greengard; Angus Nairn; Hugh C Hemmings
Regulation of neurabin I interaction with protein phosphatase 1 by phosphorylation.
Biochemistry 1999;38(39):12943-9.
1999: Zhen Yan; Jian Feng; Allen Fienberg; Paul Greengard
D(2) dopamine receptors induce mitogen-activated protein kinase and cAMP response element-binding protein phosphorylation in neurons.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(20):11607-12.
1999: Yan Zhou; Stefan D Schlussman; Ann Ho; Rudolph Spangler; Allen Fienberg; Paul Greengard; Mary Jeanne Kreek
Effects of chronic 'Binge' cocaine administration on plasma ACTH and corticosterone levels in mice deficient in DARPP-32.
Neuroendocrinology 1999;70(3):196-9.
1999: Sabine Hilfiker; Vincent A Pieribone; C Nordstedt; Paul Greengard; Andrew J Czernik
Regulation of synaptotagmin I phosphorylation by multiple protein kinases.
Journal of neurochemistry 1999;73(3):921-32.
1999: Patrick B Allen; Linda C Hsieh-Wilson; Z Yan; J Feng; Charles C Ouimet; Paul Greengard
Control of protein phosphatase I in the dendrite.
Biochemical Society transactions 1999;27(4):543-6.
1999: Angus Scrimgeour; Patrick B Allen; Allen Fienberg; Paul Greengard; John C Lawrence
Inhibitor-1 is not required for the activation of glycogen synthase by insulin in skeletal muscle.
The Journal of biological chemistry 1999;274(30):20949-52.
1999: Paul Greengard; Patrick B Allen; Angus Nairn
Beyond the dopamine receptor: the DARPP-32/protein phosphatase-1 cascade.
Neuron 1999;23(3):435-47.
1999: Akinori Nishi; Gretchen L Snyder; Allen Fienberg; Gilberto Fisone; Anita Aperia; Angus Nairn; Paul Greengard
Requirement for DARPP-32 in mediating effect of dopamine D2 receptor activation.
The European journal of neuroscience 1999;11(7):2589-92.
1999: S X Jun Cheng; Oleg Aizman; Angus Nairn; Paul Greengard; Anita Aperia
[Ca2+]i determines the effects of protein kinases A and C on activity of rat renal Na+,K+-ATPase.
The Journal of physiology 1999;518 ( Pt 1)():37-46.
1999: Ulla Holtbäck; hjalmar brismar; G F DiBona; M Fu; Paul Greengard; Anita Aperia
Receptor recruitment: a mechanism for interactions between G protein-coupled receptors.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(13):7271-5.
1999: K Ando; M Oishi; S Takeda; Koichi Iijima; T Isohara; Angus Nairn; Yutaka Kirino; Paul Greengard; Takahiro Suzuki
Role of phosphorylation of Alzheimer's amyloid precursor protein during neuronal differentiation.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1999;19(11):4421-7.
1999: Maria Lindskog; Per Svenningsson; Bertil B. Fredholm; Paul Greengard; Gilberto Fisone
Mu- and delta-opioid receptor agonists inhibit DARPP-32 phosphorylation in distinct populations of striatal projection neurons.
The European journal of neuroscience 1999;11(6):2182-6.
1999: T Isohara; A Horiuchi; T Watanabe; K Ando; Andrew J Czernik; I Uno; Paul Greengard; Angus Nairn; Takahiro Suzuki
Phosphorylation of the cytoplasmic domain of Alzheimer's beta-amyloid precursor protein at Ser655 by a novel protein kinase.
Biochemical and biophysical research communications 1999;258(2):300-5.
1999: Akinori Nishi; Gretchen L Snyder; Angus Nairn; Paul Greengard
Role of calcineurin and protein phosphatase-2A in the regulation of DARPP-32 dephosphorylation in neostriatal neurons.
Journal of neurochemistry 1999;72(5):2015-21.
1999: Allen Fienberg; C Nordstedt; HG Belting; Andrew J Czernik; Angus Nairn; Sam Gandy; Paul Greengard; Frank H Ruddle
Phylogenetically conserved CK-II phosphorylation site of the murine homeodomain protein Hoxb-6.
The Journal of experimental zoology 1999;285(1):76-84.
1999: Linda C Hsieh-Wilson; Patrick B Allen; T Watanabe; Angus Nairn; Paul Greengard
Characterization of the neuronal targeting protein spinophilin and its interactions with protein phosphatase-1.
Biochemistry 1999;38(14):4365-73.
1999: Shasta Sabo; Lorene Lanier; Annat F Ikin; OE Khorkova; Sudhir Sahasrabudhe; Paul Greengard; Joseph Buxbaum
Regulation of beta-amyloid secretion by FE65, an amyloid protein precursor-binding protein.
The Journal of biological chemistry 1999;274(12):7952-7.
1999: Hsien-Bin Huang; A Horiuchi; T Watanabe; S R Shih; Huey-Jen Tsay; H C Li; Paul Greengard; Angus Nairn
Characterization of the inhibition of protein phosphatase-1 by DARPP-32 and inhibitor-2.
The Journal of biological chemistry 1999;274(12):7870-8.
1999: S Endo; M Suzuki; M Sumi; Angus Nairn; R Morita; K Yamakawa; Paul Greengard; M Ito
Molecular identification of human G-substrate, a possible downstream component of the cGMP-dependent protein kinase cascade in cerebellar Purkinje cells.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(5):2467-72.
1999: Noboru Hiroi; Allen Fienberg; Colin N Haile; M Alburges; G R Hanson; Paul Greengard; Eric J Nestler
Neuronal and behavioural abnormalities in striatal function in DARPP-32-mutant mice.
The European journal of neuroscience 1999;11(3):1114-8.
1999: Sabine Hilfiker; Vincent A Pieribone; Andrew J Czernik; Hung-Teh Kao; George J Augustine; Paul Greengard
Synapsins as regulators of neurotransmitter release.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 1999;354(1381):269-79.
1999: Sabine Hilfiker; Paul Greengard; George J Augustine
Coupling calcium to SNARE-mediated synaptic vesicle fusion.
Nature neuroscience 1999;2(2):104-6.
1999: T Watanabe; Jun Sukegawa; I Sukegawa; S Tomita; Koichi Iijima; S Oguchi; Takahiro Suzuki; Angus Nairn; Paul Greengard
A 127-kDa protein (UV-DDB) binds to the cytoplasmic domain of the Alzheimer's amyloid precursor protein.
Journal of neurochemistry 1999;72(2):549-56.
1999: Jeffrey P Greenfield; J Tsai; Gunnar K Gouras; B Hai; Gopal Thinakaran; F Checler; Sangram S Sisodia; Paul Greengard; Huaxi Xu
Endoplasmic reticulum and trans-Golgi network generate distinct populations of Alzheimer beta-amyloid peptides.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(2):742-7.
1999: Barbara Porton; Hung-Teh Kao; Paul Greengard
Cloning of cDNAs encoding human synapsins IIa and IIb.
DNA sequence : the journal of DNA sequencing and mapping 1999;10(1):49-54.
1999: Maria Lindskog; Per Svenningsson; Bertil B. Fredholm; Paul Greengard; Gilberto Fisone
Activation of dopamine D2 receptors decreases DARPP-32 phosphorylation in striatonigral and striatopallidal projection neurons via different mechanisms.
Neuroscience 1999;88(4):1005-8.
1999: Zhen Yan; Linda C Hsieh-Wilson; Jian Feng; K Tomizawa; Patrick B Allen; Allen Fienberg; Angus Nairn; Paul Greengard
Protein phosphatase 1 modulation of neostriatal AMPA channels: regulation by DARPP-32 and spinophilin.
Nature neuroscience 1999;2(1):13-7.
1999: Artur Mayerhofer; Hugh C Hemmings; G L Snyder; Paul Greengard; S Boddien; Ulrike Berg; C Brucker
Functional dopamine-1 receptors and DARPP-32 are expressed in human ovary and granulosa luteal cells in vitro.
The Journal of clinical endocrinology and metabolism 1999;84(1):257-64.
1998: Gretchen L Snyder; Allen Fienberg; Richard Huganir; Paul Greengard
A dopamine/D1 receptor/protein kinase A/dopamine- and cAMP-regulated phosphoprotein (Mr 32 kDa)/protein phosphatase-1 pathway regulates dephosphorylation of the NMDA receptor.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1998;18(24):10297-303.
1998: John M Meredith; CA Moffatt; Anthony P Auger; G L Snyder; Paul Greengard; Jeffrey D Blaustein
Mating-related stimulation induces phosphorylation of dopamine- and cyclic AMP-regulated phosphoprotein-32 in progestin receptor-containing areas in the female rat brain.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1998;18(23):10189-95.
1998: Gunnar K Gouras; H Xu; J N Jovanovic; Joseph Buxbaum; Rong Wang; Paul Greengard; Norman Richard Relkin; Sam Gandy
Generation and regulation of beta-amyloid peptide variants by neurons.
Journal of neurochemistry 1998;71(5):1920-5.
1998: Charles C Ouimet; K C Langley-Gullion; Paul Greengard
Quantitative immunocytochemistry of DARPP-32-expressing neurons in the rat caudatoputamen.
Brain research 1998;808(1):8-12.
1998: Allen Fienberg; Noboru Hiroi; PG Mermelstein; W Song; Gretchen L Snyder; Akinori Nishi; A Cheramy; JP O'Callaghan; D B Miller; D G Cole; R Corbett; Colin N Haile; Donald C Cooper; Shao-Pii Onn; Anthony A Grace; Charles C Ouimet; Francis J White; S E Hyman; Dalton Surmeier; J Girault; Eric J Nestler; Paul Greengard
DARPP-32: regulator of the efficacy of dopaminergic neurotransmission.
Science (New York, N.Y.) 1998;281(5378):838-42.
1998: hjalmar brismar; M Asghar; R M Carey; Paul Greengard; Anita Aperia
Dopamine-induced recruitment of dopamine D1 receptors to the plasma membrane.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(10):5573-8.
1998: Sabine Hilfiker; FE Schweizer; Hung-Teh Kao; Andrew J Czernik; Paul Greengard; George J Augustine
Two sites of action for synapsin domain E in regulating neurotransmitter release.
Nature neuroscience 1998;1(1):29-35.
1998: Paul Greengard; Angus Nairn; Jean-Antoine Girault; Charles C Ouimet; Gretchen L Snyder; Gilberto Fisone; Patrick B Allen; Allen Fienberg; Akinori Nishi
The DARPP-32/protein phosphatase-1 cascade: a model for signal integration.
Brain research. Brain research reviews 1998;26(2-3):274-84.
1998: Per Svenningsson; Maria Lindskog; F Rognoni; Bertil B. Fredholm; Paul Greengard; Gilberto Fisone
Activation of adenosine A2A and dopamine D1 receptors stimulates cyclic AMP-dependent phosphorylation of DARPP-32 in distinct populations of striatal projection neurons.
Neuroscience 1998;84(1):223-8.
1998: Hung-Teh Kao; Barbara Porton; Andrew J Czernik; Jian Feng; G Yiu; M Häring; Fabio Benfenati; Paul Greengard
A third member of the synapsin gene family.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(8):4667-72.
1998: Serge N Schiffmann; F Desdouits; R Menu; Paul Greengard; J D Vincent; JJ Vanderhaeghen; Jean-Antoine Girault
Modulation of the voltage-gated sodium current in rat striatal neurons by DARPP-32, an inhibitor of protein phosphatase.
The European journal of neuroscience 1998;10(4):1312-20.
1998: Gilberto Fisone; Gretchen L Snyder; Anita Aperia; Paul Greengard
Na+,K(+)-ATPase phosphorylation in the choroid plexus: synergistic regulation by serotonin/protein kinase C and isoproterenol/cAMP-PK/PP-1 pathways.
Molecular medicine (Cambridge, Mass.) 1998;4(4):258-65.
1998: Huaxi Xu; Gunnar K Gouras; Jeffrey P Greenfield; B Vincent; J Naslund; L Mazzarelli; G Fried; J N Jovanovic; M Seeger; Norman Richard Relkin; F Liao; F Checler; Joseph Buxbaum; Brian T Chait; Gopal Thinakaran; Sangram S Sisodia; Runsheng Wang; Paul Greengard; Sam Gandy
Estrogen reduces neuronal generation of Alzheimer beta-amyloid peptides.
Nature medicine 1998;4(4):447-51.
1998: F Desdouits; JC Siciliano; Angus Nairn; Paul Greengard; Jean-Antoine Girault
Dephosphorylation of Ser-137 in DARPP-32 by protein phosphatases 2A and 2C: different roles in vitro and in striatonigral neurons.
The Biochemical journal 1998;330 ( Pt 1)():211-6.
1998: Patrick B Allen; Y G Kwon; Angus Nairn; Paul Greengard
Isolation and characterization of PNUTS, a putative protein phosphatase 1 nuclear targeting subunit.
The Journal of biological chemistry 1998;273(7):4089-95.
1998: J Desdouits-Magnen; F Desdouits; S Takeda; Li-Jyun Syu; Alan Saltiel; Joseph Buxbaum; Andrew J Czernik; Angus Nairn; Paul Greengard
Regulation of secretion of Alzheimer amyloid precursor protein by the mitogen-activated protein kinase cascade.
Journal of neurochemistry 1998;70(2):524-30.
1998: Adriana Ferreira; L S Chin; L Li; Lorene Lanier; Kenneth S Kosik; Paul Greengard
Distinct roles of synapsin I and synapsin II during neuronal development.
Molecular medicine (Cambridge, Mass.) 1998;4(1):22-8.
1998: Anita Aperia; Ann-Christine Eklöf; Ulla Holtbäck; S Nowicki; M Sundelöf; Paul Greengard
The renal dopamine system.
Advances in pharmacology (San Diego, Calif.) 1998;42():870-3.
1997: Thomas Blank; Ingrid Nijholt; Ulrich Teichert; H Kügler; H Behrsing; Allen Fienberg; Paul Greengard; Joachim Spiess
The phosphoprotein DARPP-32 mediates cAMP-dependent potentiation of striatal N-methyl-D-aspartate responses.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(26):14859-64.
1997: H B Nielander; Franco Onofri; E Schaeffer; Andrea Menegon; R Fesce; Flavia Valtorta; Paul Greengard; Fabio Benfenati
Phosphorylation-dependent effects of synapsin IIa on actin polymerization and network formation.
The European journal of neuroscience 1997;9(12):2712-22.
1997: Paola Vaccaro; Luciana Dente; Franco Onofri; Adriana Zucconi; Simone Martinelli; Flavia Valtorta; Paul Greengard; Gianni Cesareni; Fabio Benfenati
Anti-synapsin monoclonal antibodies: epitope mapping and inhibitory effects on phosphorylation and Grb2 binding.
Brain research. Molecular brain research 1997;52(1):1-16.
1997: XJ Cheng; J O Höög; Angus Nairn; Paul Greengard; Anita Aperia
Regulation of rat Na(+)-K(+)-ATPase activity by PKC is modulated by state of phosphorylation of Ser-943 by PKA.
The American journal of physiology 1997;273(6 Pt 1):C1981-6.
1997: R Schnabel; M Metzger; S Jiang; H C Hemmings; Paul Greengard; Katharina Braun
Localization of dopamine D1 receptors and dopaminoceptive neurons in the chick forebrain.
The Journal of comparative neurology 1997;388(1):146-68.
1997: G Stefani; Franco Onofri; Flavia Valtorta; Paola Vaccaro; Paul Greengard; Fabio Benfenati
Kinetic analysis of the phosphorylation-dependent interactions of synapsin I with rat brain synaptic vesicles.
The Journal of physiology 1997;504 ( Pt 3)():501-15.
1997: Akinori Nishi; Gretchen L Snyder; Paul Greengard
Bidirectional regulation of DARPP-32 phosphorylation by dopamine.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1997;17(21):8147-55.
1997: Franco Onofri; Silvia Giovedì; Paola Vaccaro; Andrew J Czernik; Flavia Valtorta; Pietro De Camilli; Paul Greengard; Fabio Benfenati
Synapsin I interacts with c-Src and stimulates its tyrosine kinase activity.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(22):12168-73.
1997: Patrick B Allen; Charles C Ouimet; Paul Greengard
Spinophilin, a novel protein phosphatase 1 binding protein localized to dendritic spines.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(18):9956-61.
1997: XJ Cheng; Gilberto Fisone; Oleg Aizman; Roman I Aizman; R Levenson; Paul Greengard; Anita Aperia
PKA-mediated phosphorylation and inhibition of Na(+)-K(+)-ATPase in response to beta-adrenergic hormone.
The American journal of physiology 1997;273(3 Pt 1):C893-901.
1997: Roger Belusa; Z M Wang; T Matsubara; B Sahlgren; I Dulubova; Angus Nairn; E Ruoslahti; Paul Greengard; Anita Aperia
Mutation of the protein kinase C phosphorylation site on rat alpha1 Na+,K+-ATPase alters regulation of intracellular Na+ and pH and influences cell shape and adhesiveness.
The Journal of biological chemistry 1997;272(32):20179-84.
1997: K C Langley; Clare M Bergson; Paul Greengard; Charles C Ouimet
Co-localization of the D1 dopamine receptor in a subset of DARPP-32-containing neurons in rat caudate-putamen.
Neuroscience 1997;78(4):977-83.
1997: M Seeger; C Nordstedt; Suzana Petanceska; Dora M. Kovacs; Gunnar K Gouras; S Hahne; Paul E Fraser; L Levesque; Andrew J Czernik; Peter St George-Hyslop; Sangram S Sisodia; Gopal Thinakaran; Rudolph E Tanzi; Paul Greengard; Sam Gandy
Evidence for phosphorylation and oligomeric assembly of presenilin 1.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(10):5090-4.
1997: Takahiro Suzuki; K Ando; T Isohara; M Oishi; G S Lim; Y Satoh; Wilma Wasco; Rudolph E Tanzi; Angus Nairn; Paul Greengard; Sam Gandy; Yutaka Kirino
Phosphorylation of Alzheimer beta-amyloid precursor-like proteins.
Biochemistry 1997;36(15):4643-9.
1997: Huaxi Xu; D Sweeney; Rong Wang; Gopal Thinakaran; Amy Lo; Sangram S Sisodia; Paul Greengard; Sam Gandy
Generation of Alzheimer beta-amyloid protein in the trans-Golgi network in the apparent absence of vesicle formation.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(8):3748-52.
1997: Y G Kwon; HB Huang; F Desdouits; Jean-Antoine Girault; Paul Greengard; Angus Nairn
Characterization of the interaction between DARPP-32 and protein phosphatase 1 (PP-1): DARPP-32 peptides antagonize the interaction of PP-1 with binding proteins.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(8):3536-41.
1997: HB Huang; A Horiuchi; J Goldberg; Paul Greengard; Angus Nairn
Site-directed mutagenesis of amino acid residues of protein phosphatase 1 involved in catalysis and inhibitor binding.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(8):3530-5.
1997: Y G Kwon; Seok-Yong Lee; Yongwon Choi; Paul Greengard; Angus Nairn
Cell cycle-dependent phosphorylation of mammalian protein phosphatase 1 by cdc2 kinase.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(6):2168-73.
1997: S Nowicki; S L Chen; Oleg Aizman; XJ Cheng; D Li; C Nowicki; Angus Nairn; Paul Greengard; Anita Aperia
20-Hydroxyeicosa-tetraenoic acid (20 HETE) activates protein kinase C. Role in regulation of rat renal Na+,K+-ATPase.
The Journal of clinical investigation 1997;99(6):1224-30.
1997: M Oishi; Angus Nairn; Andrew J Czernik; G S Lim; T Isohara; Sam Gandy; Paul Greengard; Takahiro Suzuki
The cytoplasmic domain of Alzheimer's amyloid precursor protein is phosphorylated at Thr654, Ser655, and Thr668 in adult rat brain and cultured cells.
Molecular medicine (Cambridge, Mass.) 1997;3(2):111-23.
1996: Michael Gordon Kaplitt; Gunnar K Gouras; H Makimura; J Jovanovic; D Sweeney; Paul Greengard; Norman Richard Relkin; Sam Gandy
Apolipoprotein E, A beta-amyloid, and the molecular pathology of Alzheimer's disease. Therapeutic implications.
Annals of the New York Academy of Sciences 1996;802():42-9.
1996: A F Ikin; Willem ANNAERT; Kohji Takei; Pietro De Camilli; R Jahn; Paul Greengard; Joseph Buxbaum
Alzheimer amyloid protein precursor is localized in nerve terminal preparations to Rab5-containing vesicular organelles distinct from those implicated in the synaptic vesicle pathway.
The Journal of biological chemistry 1996;271(50):31783-6.
1996: F Desdouits; Joseph Buxbaum; J Desdouits-Magnen; Angus Nairn; Paul Greengard
Amyloid beta peptide formation in cell-free preparations. Regulation by protein kinase C, calmodulin, and calcineurin.
The Journal of biological chemistry 1996;271(40):24670-4.
1996: B Lu; Andrew J Czernik; S Popov; T Wang; M M Poo; Paul Greengard
Expression of synapsin I correlates with maturation of the neuromuscular synapse.
Neuroscience 1996;74(4):1087-97.
1996: T A Ryan; L Li; L S Chin; Paul Greengard; Stephen J Smith
Synaptic vesicle recycling in synapsin I knock-out mice.
The Journal of cell biology 1996;134(5):1219-27.
1996: N S Logvinenko; I Dulubova; Natalya U Fedosova; S H Larsson; Angus Nairn; M Esmann; Paul Greengard; Anita Aperia
Phosphorylation by protein kinase C of serine-23 of the alpha-1 subunit of rat Na+,K(+)-ATPase affects its conformational equilibrium.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(17):9132-7.
1996: Y Qian; D S Chao; D R Santillano; Trudy L Cornwell; Angus Nairn; Paul Greengard; T M Lincoln; David S Bredt
cGMP-dependent protein kinase in dorsal root ganglion: relationship with nitric oxide synthase and nociceptive neurons.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1996;16(10):3130-8.
1996: Huaxi Xu; D Sweeney; Paul Greengard; Sam Gandy
Metabolism of Alzheimer beta-amyloid precursor protein: regulation by protein kinase A in intact cells and in a cell-free system.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(9):4081-4.
1996: J N Jovanovic; Fabio Benfenati; Chris Siow; T S Sihra; Jasbinder S Sanghera; S L Pelech; Paul Greengard; Andrew J Czernik
Neurotrophins stimulate phosphorylation of synapsin I by MAP kinase and regulate synapsin I-actin interactions.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(8):3679-83.
1996: Gary D Smith; Don P Wolf; K C Trautman; E F da Cruz e Silva; Paul Greengard; S Vijayaraghavan
Primate sperm contain protein phosphatase 1, a biochemical mediator of motility.
Biology of reproduction 1996;54(3):719-27.
1996: S Vijayaraghavan; D T Stephens; K Trautman; Gary D Smith; B Khatra; E F da Cruz e Silva; Paul Greengard
Sperm motility development in the epididymis is associated with decreased glycogen synthase kinase-3 and protein phosphatase 1 activity.
Biology of reproduction 1996;54(3):709-18.
1996: Z Zhou; Jonathan D. Smith; Paul Greengard; Sam Gandy
Alzheimer amyloid-beta peptide forms denaturant-resistant complex with type epsilon 3 but not type epsilon 4 isoform of native apolipoprotein E.
Molecular medicine (Cambridge, Mass.) 1996;2(2):175-80.
1996: Joseph Buxbaum; Paul Greengard
Regulation of APP processing by intra- and intercellular signals.
Annals of the New York Academy of Sciences 1996;777():327-31.
1996: Adriana Ferreira; L Li; L S Chin; Paul Greengard; Kenneth S Kosik
Postsynaptic element contributes to the delay in synaptogenesis in synapsin I-deficient neurons.
Molecular and cellular neurosciences 1996;8(4):286-99.
1995: D Li; Anita Aperia; G Celsi; E F da Cruz e Silva; Paul Greengard; B Meister
Protein phosphatase-1 in the kidney: evidence for a role in the regulation of medullary Na(+)-K(+)-ATPase.
The American journal of physiology 1995;269(5 Pt 2):F673-80.
1995: Huaxi Xu; Paul Greengard; Sam Gandy
Regulated formation of Golgi secretory vesicles containing Alzheimer beta-amyloid precursor protein.
The Journal of biological chemistry 1995;270(40):23243-5.
1995: H B Nielander; Franco Onofri; Flavia Valtorta; Giampietro Schiavo; C Montecucco; Paul Greengard; Fabio Benfenati
Phosphorylation of VAMP/synaptobrevin in synaptic vesicles by endogenous protein kinases.
Journal of neurochemistry 1995;65(4):1712-20.
1995: L Li; L S Chin; Oleg Shupliakov; Lennart Brodin; T S Sihra; Oivind Hvalby; Vidar Jensen; D Zheng; J O McNamara; Paul Greengard
Impairment of synaptic vesicle clustering and of synaptic transmission, and increased seizure propensity, in synapsin I-deficient mice.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(20):9235-9.
1995: L S Chin; L Li; Adriana Ferreira; Kenneth S Kosik; Paul Greengard
Impairment of axonal development and of synaptogenesis in hippocampal neurons of synapsin I-deficient mice.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(20):9230-4.
1995: Adriana Ferreira; H Q Han; Paul Greengard; Kenneth S Kosik
Suppression of synapsin II inhibits the formation and maintenance of synapses in hippocampal culture.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(20):9225-9.
1995: J Goldberg; H B Huang; Y G Kwon; Paul Greengard; Angus Nairn; John Kuriyan
Three-dimensional structure of the catalytic subunit of protein serine/threonine phosphatase-1.
Nature 1995;376(6543):745-53.
1995: L Li; L S Chin; Paul Greengard; N G Copeland; D J Gilbert; N A Jenkins
Localization of the synapsin II (SYN2) gene to human chromosome 3 and mouse chromosome 6.
Genomics 1995;28(2):365-6.
1995: E F da Cruz e Silva; O A da Cruz e Silva; C T Zaia; Paul Greengard
Inhibition of protein phosphatase 1 stimulates secretion of Alzheimer amyloid precursor protein.
Molecular medicine (Cambridge, Mass.) 1995;1(5):535-41.
1995: Vincent A Pieribone; Oleg Shupliakov; Lennart Brodin; S Hilfiker-Rothenfluh; Andrew J Czernik; Paul Greengard
Distinct pools of synaptic vesicles in neurotransmitter release.
Nature 1995;375(6531):493-7.
1995: G Fried; H Q Han; B Meister; T Hökfelt; Paul Greengard
Laminin and neuropeptide Y are increased by synapsin transfection in cultured NG108-15 neuroblastoma/glioma hybrid cells.
Journal of neurochemistry 1995;64(6):2674-80.
1995: E F da Cruz e Silva; C A Fox; Charles C Ouimet; E Gustafson; Stanley J Watson Jr; Paul Greengard
Differential expression of protein phosphatase 1 isoforms in mammalian brain.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1995;15(5 Pt 1):3375-89.
1995: F Desdouits; D Cohen; Angus Nairn; Paul Greengard; Jean-Antoine Girault
Phosphorylation of DARPP-32, a dopamine- and cAMP-regulated phosphoprotein, by casein kinase I in vitro and in vivo.
The Journal of biological chemistry 1995;270(15):8772-8.
1995: Charles C Ouimet; E F da Cruz e Silva; Paul Greengard
The alpha and gamma 1 isoforms of protein phosphatase 1 are highly and specifically concentrated in dendritic spines.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(8):3396-400.
1995: F Desdouits; J C Siciliano; Paul Greengard; Jean-Antoine Girault
Dopamine- and cAMP-regulated phosphoprotein DARPP-32: phosphorylation of Ser-137 by casein kinase I inhibits dephosphorylation of Thr-34 by calcineurin.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(7):2682-5.
1995: Pierre-Emmanuel Ceccaldi; Fabio Grohovaz; Fabio Benfenati; E Chieregatti; Paul Greengard; Flavia Valtorta
Dephosphorylated synapsin I anchors synaptic vesicles to actin cytoskeleton: an analysis by videomicroscopy.
The Journal of cell biology 1995;128(5):905-12.
1995: Gilberto Fisone; Gretchen L Snyder; J Fryckstedt; M J Caplan; Anita Aperia; Paul Greengard
Na+,K(+)-ATPase in the choroid plexus. Regulation by serotonin/protein kinase C pathway.
The Journal of biological chemistry 1995;270(6):2427-30.
1995: Flavia Valtorta; N Iezzi; F Benfenati; B Lu; M M Poo; Paul Greengard
Accelerated structural maturation induced by synapsin I at developing neuromuscular synapses of Xenopus laevis.
The European journal of neuroscience 1995;7(2):261-70.
1995: Dalton Surmeier; José Bargas; H C Hemmings; Angus Nairn; Paul Greengard
Modulation of calcium currents by a D1 dopaminergic protein kinase/phosphatase cascade in rat neostriatal neurons.
Neuron 1995;14(2):385-97.
1995: F Desdouits; J J Cheetham; H B Huang; Y G Kwon; E F da Cruz e Silva; Patrice DENEFLE; M E Ehrlich; Angus Nairn; Paul Greengard; Jean-Antoine Girault
Mechanism of inhibition of protein phosphatase 1 by DARPP-32: studies with recombinant DARPP-32 and synthetic peptides.
Biochemical and biophysical research communications 1995;206(2):652-8.
1995: J Alder; H Kanki; F Valtorta; Paul Greengard; Mu-ming Poo
Overexpression of synaptophysin enhances neurotransmitter secretion at Xenopus neuromuscular synapses.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1995;15(1 Pt 2):511-9.
1995: Y Yamagata; Kunihiko Obata; Paul Greengard; A J Czernik
Increase in synapsin I phosphorylation implicates a presynaptic component in septal kindling.
Neuroscience 1995;64(1):1-4.
1994: Gretchen L Snyder; Gilberto Fisone; Paul Greengard
Phosphorylation of DARPP-32 is regulated by GABA in rat striatum and substantia nigra.
Journal of neurochemistry 1994;63(5):1766-71.
1994: Charles C Ouimet; K D Baerwald; Sam Gandy; Paul Greengard
Immunocytochemical localization of amyloid precursor protein in rat brain.
The Journal of comparative neurology 1994;348(2):244-60.
1994: T J Chilcote; Chris Siow; E Schaeffer; Paul Greengard; G Thiel
Synapsin IIa bundles actin filaments.
Journal of neurochemistry 1994;63(4):1568-71.
1994: N A Simonian; T Elvhage; A J Czernik; Paul Greengard; Bradley T Hyman
Calcium/calmodulin-dependent protein kinase II immunostaining is preserved in Alzheimer's disease hippocampal neurons.
Brain research 1994;657(1-2):294-9.
1994: H Q Han; Paul Greengard
Remodeling of cytoskeletal architecture of nonneuronal cells induced by synapsin.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(18):8557-61.
1994: Jan Näslund; A Schierhorn; U Hellman; Lars Lannfelt; Allen D Roses; Lars O Tjernberg; J Silberring; Sam Gandy; Bengt Winblad; Paul Greengard
Relative abundance of Alzheimer A beta amyloid peptide variants in Alzheimer disease and normal aging.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(18):8378-82.
1994: L S Chin; L Li; Paul Greengard
Neuron-specific expression of the synapsin II gene is directed by a specific core promoter and upstream regulatory elements.
The Journal of biological chemistry 1994;269(28):18507-13.
1994: Peter S McPherson; Andrew J Czernik; T J Chilcote; Franco Onofri; Fabio Benfenati; Paul Greengard; Joseph Schlessinger; Pietro De Camilli
Interaction of Grb2 via its Src homology 3 domains with synaptic proteins including synapsin I.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(14):6486-90.
1994: M Dohadwala; E F da Cruz e Silva; Frederick L Hall; Richard Williams; D A Carbonaro-Hall; Angus Nairn; Paul Greengard; Norbert Berndt
Phosphorylation and inactivation of protein phosphatase 1 by cyclin-dependent kinases.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(14):6408-12.
1994: Adriana Ferreira; Kenneth S Kosik; Paul Greengard; H Q Han
Aberrant neurites and synaptic vesicle protein deficiency in synapsin II-depleted neurons.
Science (New York, N.Y.) 1994;264(5161):977-9.
1994: Joseph Buxbaum; A A Ruefli; C A Parker; A M Cypess; Paul Greengard
Calcium regulates processing of the Alzheimer amyloid protein precursor in a protein kinase C-independent manner.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(10):4489-93.
1994: A B Jaffe; C. Dominique Toran-Allerand; Paul Greengard; Sam Gandy
Estrogen regulates metabolism of Alzheimer amyloid beta precursor protein.
The Journal of biological chemistry 1994;269(18):13065-8.
1994: K Miles; S S Audigier; Paul Greengard; Richard Huganir
Autoregulation of phosphorylation of the nicotinic acetylcholine receptor.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1994;14(5 Pt 2):3271-9.
1994: G L Caporaso; Kohji Takei; Sam Gandy; Michela Matteoli; O Mundigl; Paul Greengard; Pietro De Camilli
Morphologic and biochemical analysis of the intracellular trafficking of the Alzheimer beta/A4 amyloid precursor protein.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1994;14(5 Pt 2):3122-38.
1994: E Schaeffer; J Alder; Paul Greengard; M M Poo
Synapsin IIa accelerates functional development of neuromuscular synapses.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(9):3882-6.
1994: Anita Aperia; Ulla Holtbäck; M L Syrén; L B Svensson; J Fryckstedt; Paul Greengard
Activation/deactivation of renal Na+,K(+)-ATPase: a final common pathway for regulation of natriuresis.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1994;8(6):436-9.
1994: T Suzuki; M Oishi; D R Marshak; Andrew J Czernik; Angus Nairn; Paul Greengard
Cell cycle-dependent regulation of the phosphorylation and metabolism of the Alzheimer amyloid precursor protein.
The EMBO journal 1994;13(5):1114-22.
1994: Stefan Brené; Nils Lindefors; M Ehrlich; T Taubes; A Horiuchi; J Kopp; Håkan Hall; Göran C Sedvall; Paul Greengard; H Persson
Expression of mRNAs encoding ARPP-16/19, ARPP-21, and DARPP-32 in human brain tissue.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1994;14(3 Pt 1):985-98.
1994: Sam Gandy; G Caporaso; Joseph Buxbaum; Blas Frangione; Paul Greengard
APP processing, A beta-amyloidogenesis, and the pathogenesis of Alzheimer's disease.
Neurobiology of aging 1994;15(2):253-6.
1994: Paul Greengard; Fabio Benfenati; Flavia Valtorta
Synapsin I, an actin-binding protein regulating synaptic vesicle traffic in the nerve terminal.
Advances in second messenger and phosphoprotein research 1994;29():31-45.
1994: Sam Gandy; Paul Greengard
Processing of Alzheimer A beta-amyloid precursor protein: cell biology, regulation, and role in Alzheimer disease.
International review of neurobiology 1994;36():29-50.
1994: Sam Gandy; Paul Greengard
Regulated cleavage of the Alzheimer amyloid precursor protein: molecular and cellular basis.
Biochimie 1994;76(3-4):300-3.
1993: Joseph Buxbaum; J L Christensen; A A Ruefli; Paul Greengard; Jeanne F Loring
Expression of APP in brains of transgenic mice containing the entire human APP gene.
Biochemical and biophysical research communications 1993;197(2):639-45.
1993: J Knops; Sam Gandy; Paul Greengard; I Lieberburg; Sukanto Sinha
Serine phosphorylation of the secreted extracellular domain of APP.
Biochemical and biophysical research communications 1993;197(2):380-5.
1993: O A da Cruz e Silva; K Iverfeldt; Tilman Oltersdorf; S Sinha; I Lieberburg; T V Ramabhadran; T Suzuki; Sangram S Sisodia; Sam Gandy; Paul Greengard
Regulated cleavage of Alzheimer beta-amyloid precursor protein in the absence of the cytoplasmic tail.
Neuroscience 1993;57(4):873-7.
1993: Fabio Benfenati; Flavia Valtorta; M C Rossi; Franco Onofri; T Sihra; Paul Greengard
Interactions of synapsin I with phospholipids: possible role in synaptic vesicle clustering and in the maintenance of bilayer structures.
The Journal of cell biology 1993;123(6 Pt 2):1845-55.
1993: Gretchen L Snyder; Gilberto Fisone; P Morino; V Gundersen; O P Ottersen; T Hökfelt; Paul Greengard
Regulation by the neuropeptide cholecystokinin (CCK-8S) of protein phosphorylation in the neostriatum.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(23):11277-81.
1993: P Neyroz; F Desdouits; Fabio Benfenati; J R Knutson; Paul Greengard; Jean-Antoine Girault
Study of the conformation of DARPP-32, a dopamine- and cAMP-regulated phosphoprotein, by fluorescence spectroscopy.
The Journal of biological chemistry 1993;268(32):24022-31.
1993: Joseph Buxbaum; Edward H Koo; Paul Greengard
Protein phosphorylation inhibits production of Alzheimer amyloid beta/A4 peptide.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(19):9195-8.
1993: Sam Gandy; G L Caporaso; Joseph Buxbaum; O de Cruz Silva; K Iverfeldt; C Nordstedt; T Suzuki; Andrew J Czernik; Angus Nairn; Paul Greengard
Protein phosphorylation regulates relative utilization of processing pathways for Alzheimer beta/A4 amyloid precursor protein.
Annals of the New York Academy of Sciences 1993;695():117-21.
1993: Pierre-Emmanuel Ceccaldi; Fabio Benfenati; E Chieregatti; Paul Greengard; Flavia Valtorta
Rapid binding of synapsin I to F- and G-actin. A study using fluorescence resonance energy transfer.
FEBS letters 1993;329(3):301-5.
1993: Helen Barbas; E L Gustafson; Paul Greengard
Comparison of the immunocytochemical localization of DARPP-32 and I-1 in the amygdala and hippocampus of the rhesus monkey.
The Journal of comparative neurology 1993;334(1):1-18.
1993: B Lu; W M Fu; Paul Greengard; M M Poo
Calcitonin gene-related peptide potentiates synaptic responses at developing neuromuscular junction.
Nature 1993;363(6424):76-9.
1993: K Iverfeldt; S Ivar Walaas; Paul Greengard
Altered processing of Alzheimer amyloid precursor protein in response to neuronal degeneration.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(9):4146-50.
1993: K Tsou; Gretchen L Snyder; Paul Greengard
Nitric oxide/cGMP pathway stimulates phosphorylation of DARPP-32, a dopamine- and cAMP-regulated phosphoprotein, in the substantia nigra.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(8):3462-5.
1993: K Tsou; Jean-Antoine Girault; Paul Greengard
Dopamine D1 agonist SKF 38393 increases the state of phosphorylation of ARPP-21 in substantia nigra.
Journal of neurochemistry 1993;60(3):1043-6.
1993: L Li; T Suzuki; N Mori; Paul Greengard
Identification of a functional silencer element involved in neuron-specific expression of the synapsin I gene.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(4):1460-4.
1993: Paul Greengard; Flavia Valtorta; Andrew J Czernik; Fabio Benfenati
Synaptic vesicle phosphoproteins and regulation of synaptic function.
Science (New York, N.Y.) 1993;259(5096):780-5.
1993: J L Rubenstein; Paul Greengard; Andrew J Czernik
Calcium-dependent serine phosphorylation of synaptophysin.
Synapse (New York, N.Y.) 1993;13(2):161-72.
1993: T V Ramabhadran; Sam Gandy; Jorge Ghiso; Andrew J Czernik; D Ferris; R Bhasin; Dmitry Goldgaber; Blas Frangione; Paul Greengard
Proteolytic processing of human amyloid beta protein precursor in insect cells. Major carboxyl-terminal fragment is identical to its human counterpart.
The Journal of biological chemistry 1993;268(3):2009-12.
1993: C Nordstedt; G L Caporaso; J Thyberg; Sam Gandy; Paul Greengard
Identification of the Alzheimer beta/A4 amyloid precursor protein in clathrin-coated vesicles purified from PC12 cells.
The Journal of biological chemistry 1993;268(1):608-12.
1993: S Ivar Walaas; Paul Greengard
ARPP-39, a membrane-associated substrate for cyclic AMP-dependent protein kinase present in neostriatal neurons.
Journal of molecular neuroscience : MN 1993;4(2):73-88.
1993: F Ibarra; Anita Aperia; L B Svensson; Ann-Christine Eklöf; Paul Greengard
Bidirectional regulation of Na+,K(+)-ATPase activity by dopamine and an alpha-adrenergic agonist.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(1):21-4.
1992: Sam Gandy; G L Caporaso; T V Ramabhadran; T Suzuki; Joseph Buxbaum; C Nordstedt; K Iverfeldt; Andrew J Czernik; Angus Nairn; Paul Greengard
Characterization of alternative routes for processing of the Alzheimer beta/A4-amyloid precursor protein. Differential effects of phorbol esters and chloroquine.
Annals of the New York Academy of Sciences 1992;674():203-17.
1992: F Torri Tarelli; M Bossi; R Fesce; Paul Greengard; Flavia Valtorta
Synapsin I partially dissociates from synaptic vesicles during exocytosis induced by electrical stimulation.
Neuron 1992;9(6):1143-53.
1992: E L Gustafson; M E Ehrlich; P Trivedi; Paul Greengard
Developmental regulation of phosphoprotein gene expression in the caudate-putamen of rat: an in situ hybridization study.
Neuroscience 1992;51(1):65-75.
1992: Joseph Buxbaum; M Oishi; H I Chen; R Pinkas-Kramarski; E A Jaffe; Sam Gandy; Paul Greengard
Cholinergic agonists and interleukin 1 regulate processing and secretion of the Alzheimer beta/A4 amyloid protein precursor.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(21):10075-8.
1992: J Alder; Z P Xie; F Valtorta; Paul Greengard; M Poo
Antibodies to synaptophysin interfere with transmitter secretion at neuromuscular synapses.
Neuron 1992;9(4):759-68.
1992: Fabio Benfenati; Flavia Valtorta; J L Rubenstein; F S Gorelick; Paul Greengard; A J Czernik
Synaptic vesicle-associated Ca2+/calmodulin-dependent protein kinase II is a binding protein for synapsin I.
Nature 1992;359(6394):417-20.
1992: C C Ouimet; Anthony-Samuel LaMantia; Patricia S Goldman-Rakic; Pasko Rakic; Paul Greengard
Immunocytochemical localization of DARPP-32, a dopamine and cyclic-AMP-regulated phosphoprotein, in the primate brain.
The Journal of comparative neurology 1992;323(2):209-18.
1992: Sam Gandy; Joseph Buxbaum; T Suzuki; T V Ramabhadran; G L Caporaso; Angus Nairn; Paul Greengard
The nature and metabolism of potentially amyloidogenic carboxyl-terminal fragments of the Alzheimer beta/A4-amyloid precursor protein: some technical notes.
Neurobiology of aging 1992;13(5):601-3.
1992: Hugh C Hemmings; Jean-Antoine Girault; Angus Nairn; G Bertuzzi; Paul Greengard
Distribution of protein phosphatase inhibitor-1 in brain and peripheral tissues of various species: comparison with DARPP-32.
Journal of neurochemistry 1992;59(3):1053-61.
1992: Anita Aperia; F Ibarra; L B Svensson; C Klee; Paul Greengard
Calcineurin mediates alpha-adrenergic stimulation of Na+,K(+)-ATPase activity in renal tubule cells.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(16):7394-7.
1992: Gretchen L Snyder; Jean-Antoine Girault; J Y Chen; Andrew J Czernik; J W Kebabian; J A Nathanson; Paul Greengard
Phosphorylation of DARPP-32 and protein phosphatase inhibitor-1 in rat choroid plexus: regulation by factors other than dopamine.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1992;12(8):3071-83.
1992: J Alder; B Lu; F Valtorta; Paul Greengard; Mu-ming Poo
Calcium-dependent transmitter secretion reconstituted in Xenopus oocytes: requirement for synaptophysin.
Science (New York, N.Y.) 1992;257(5070):657-61.
1992: Marina R Picciotto; Jonathan A Cohn; G Bertuzzi; Paul Greengard; Angus Nairn
Phosphorylation of the cystic fibrosis transmembrane conductance regulator.
The Journal of biological chemistry 1992;267(18):12742-52.
1992: R Fesce; Fabio Benfenati; Paul Greengard; Flavia Valtorta
Effects of the neuronal phosphoprotein synapsin I on actin polymerization. II. Analytical interpretation of kinetic curves.
The Journal of biological chemistry 1992;267(16):11289-99.
1992: Flavia Valtorta; Paul Greengard; R Fesce; E Chieregatti; Fabio Benfenati
Effects of the neuronal phosphoprotein synapsin I on actin polymerization. I. Evidence for a phosphorylation-dependent nucleating effect.
The Journal of biological chemistry 1992;267(16):11281-8.
1992: T Suzuki; Angus Nairn; Sam Gandy; Paul Greengard
Phosphorylation of Alzheimer amyloid precursor protein by protein kinase C.
Neuroscience 1992;48(4):755-61.
1992: Chris Siow; T J Chilcote; Fabio Benfenati; Paul Greengard; G Thiel
Synapsin IIa: expression in insect cells, purification, and characterization.
Biochemistry 1992;31(17):4268-75.
1992: James Mandell; A J Czernik; Pietro De Camilli; Paul Greengard; E Townes-Anderson
Differential expression of synapsins I and II among rat retinal synapses.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1992;12(5):1736-49.
1992: Flavia Valtorta; Fabio Benfenati; Paul Greengard
Structure and function of the synapsins.
The Journal of biological chemistry 1992;267(11):7195-8.
1992: G L Caporaso; Sam Gandy; Joseph Buxbaum; T V Ramabhadran; Paul Greengard
Protein phosphorylation regulates secretion of Alzheimer beta/A4 amyloid precursor protein.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(7):3055-9.
1992: G L Caporaso; Sam Gandy; Joseph Buxbaum; Paul Greengard
Chloroquine inhibits intracellular degradation but not secretion of Alzheimer beta/A4 amyloid precursor protein.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(6):2252-6.
1992: Sam Gandy; Paul Greengard
Amyloidogenesis in Alzheimer's disease: some possible therapeutic opportunities.
Trends in pharmacological sciences 1992;13(3):108-13.
1992: B Lu; Paul Greengard; M M Poo
Exogenous synapsin I promotes functional maturation of developing neuromuscular synapses.
Neuron 1992;8(3):521-9.
1992: Fabio Benfenati; Flavia Valtorta; E Chieregatti; Paul Greengard
Interaction of free and synaptic vesicle-bound synapsin I with F-actin.
Neuron 1992;8(2):377-86.
1992: Jean-Antoine Girault; B Chamak; G Bertuzzi; H Tixier; J K Wang; D T Pang; Paul Greengard
Protein phosphotyrosine in mouse brain: developmental changes and regulation by epidermal growth factor, type I insulin-like growth factor, and insulin.
Journal of neurochemistry 1992;58(2):518-28.
1992: Robert A Nichols; T J Chilcote; Andrew J Czernik; Paul Greengard
Synapsin I regulates glutamate release from rat brain synaptosomes.
Journal of neurochemistry 1992;58(2):783-5.
1992: Sam Gandy; R Bhasin; T V Ramabhadran; Edward H Koo; Donald L Price; Dmitry Goldgaber; Paul Greengard
Alzheimer beta/A4-amyloid precursor protein: evidence for putative amyloidogenic fragment.
Journal of neurochemistry 1992;58(1):383-6.
1991: Alejandro M Bertorello; Anita Aperia; S I Walaas; Angus Nairn; Paul Greengard
Phosphorylation of the catalytic subunit of Na+,K(+)-ATPase inhibits the activity of the enzyme.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(24):11359-62.
1991: M E Ehrlich; Paul Greengard
Characterization of rat ARPP-21 mRNA: sequence analysis, tissue distribution, and regulation.
Journal of neurochemistry 1991;57(6):1985-91.
1991: C Nordstedt; Sam Gandy; Irina Alafuzoff; G L Caporaso; K Iverfeldt; J A Grebb; Bengt Winblad; Paul Greengard
Alzheimer beta/A4 amyloid precursor protein in human brain: aging-associated increases in holoprotein and in a proteolytic fragment.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(20):8910-4.
1991: Björn Meister; M Schultzberg; H C Hemmings; Paul Greengard; M Goldstein; Tomas Hökfelt
Dopamine- and adenosine-3',5'-monophosphate (cAMP)-regulated phosphoprotein of 32 kDa (DARPP-32) in the adrenal gland: immunohistochemical localization.
Journal of the autonomic nervous system 1991;36(1):75-84.
1991: Björn Meister; Ulf Arvidsson; H C Hemmings; Paul Greengard; Tomas Hökfelt
Dopamine- and adenosine-3':5'-monophosphate (cAMP)-regulated phosphoprotein of Mr 32,000 (DARPP-32) in the retina of cat, monkey and human.
Neuroscience letters 1991;131(1):66-70.
1991: Paul Greengard; J Jen; Angus Nairn; C F Stevens
Enhancement of the glutamate response by cAMP-dependent protein kinase in hippocampal neurons.
Science (New York, N.Y.) 1991;253(5024):1135-8.
1991: S I Walaas; Paul Greengard
Protein phosphorylation and neuronal function.
Pharmacological reviews 1991;43(3):299-349.
1991: Björn Meister; J Askergren; G Tunevall; H C Hemmings; Paul Greengard
Identification of a dopamine- and 3'5'-cyclic adenosine monophosphate-regulated phosphoprotein of 32 kD (DARPP-32) in parathyroid hormone-producing cells of the human parathyroid gland.
Journal of endocrinological investigation 1991;14(8):655-61.
1991: Y Yamagata; Andrew J Czernik; Paul Greengard
Active catalytic fragment of Ca2+/calmodulin-dependent protein kinase II. Purification, characterization, and structural analysis.
The Journal of biological chemistry 1991;266(23):15391-7.
1991: E L Gustafson; Jean-Antoine Girault; Hugh C Hemmings; Angus Nairn; Paul Greengard
Immunocytochemical localization of phosphatase inhibitor-1 in rat brain.
The Journal of comparative neurology 1991;310(2):170-88.
1991: M Bähler; Ronald L. Klein; J K Wang; Fabio Benfenati; Paul Greengard
A novel synaptic vesicle-associated phosphoprotein: SVAPP-120.
Journal of neurochemistry 1991;57(2):423-30.
1991: D Piomelli; Paul Greengard
Bidirectional control of phospholipase A2 activity by Ca2+/calmodulin-dependent protein kinase II, cAMP-dependent protein kinase, and casein kinase II.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(15):6770-4.
1991: T Lüthi; R S Haltiwanger; Paul Greengard; M Bähler
Synapsins contain O-linked N-acetylglucosamine.
Journal of neurochemistry 1991;56(5):1493-8.
1991: R Llinás; John Gruner; Mutsuyuki Sugimori; T L McGuinness; Paul Greengard
Regulation by synapsin I and Ca(2+)-calmodulin-dependent protein kinase II of the transmitter release in squid giant synapse.
The Journal of physiology 1991;436():257-82.
1991: G Thiel; Paul Greengard; T C Südhof
Characterization of tissue-specific transcription by the human synapsin I gene promoter.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(8):3431-5.
1991: Anita Aperia; J Fryckstedt; L Svensson; H C Hemmings; Angus Nairn; Paul Greengard
Phosphorylated Mr 32,000 dopamine- and cAMP-regulated phosphoprotein inhibits Na+,K(+)-ATPase activity in renal tubule cells.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(7):2798-801.
1991: M F Ho; M Bähler; Andrew J Czernik; W Schiebler; F J Kézdy; E T Kaiser; Paul Greengard
Synapsin I is a highly surface-active molecule.
The Journal of biological chemistry 1991;266(9):5600-7.
1991: H Q Han; Robert A Nichols; M R Rubin; M Bähler; Paul Greengard
Induction of formation of presynaptic terminals in neuroblastoma cells by synapsin IIb.
Nature 1991;349(6311):697-700.
1991: Fabio Benfenati; Flavia Valtorta; Paul Greengard
Computer modeling of synapsin I binding to synaptic vesicles and F-actin: implications for regulation of neurotransmitter release.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(2):575-9.
1991: A J Czernik; J A Girault; Angus Nairn; J Chen; G Snyder; J Kebabian; Paul Greengard
Production of phosphorylation state-specific antibodies.
Methods in enzymology 1991;201():264-83.
1990: J A Grebb; Paul Greengard
An analysis of synapsin II, a neuronal phosphoprotein, in postmortem brain tissue from alcoholic and neuropsychiatrically ill adults and medically ill children and young adults.
Archives of general psychiatry 1990;47(12):1149-56.
1990: Hugh C Hemmings; Angus Nairn; J I Elliott; Paul Greengard
Synthetic peptide analogs of DARPP-32 (Mr 32,000 dopamine- and cAMP-regulated phosphoprotein), an inhibitor of protein phosphatase-1. Phosphorylation, dephosphorylation, and inhibitory activity.
The Journal of biological chemistry 1990;265(33):20369-76.
1990: Jean-Antoine Girault; Hugh C Hemmings; stevin zorn; E L Gustafson; Paul Greengard
Characterization in mammalian brain of a DARPP-32 serine kinase identical to casein kinase II.
Journal of neurochemistry 1990;55(5):1772-83.
1990: J W Lin; Mutsuyuki Sugimori; Rodolfo R Llinás; T L McGuinness; Paul Greengard
Effects of synapsin I and calcium/calmodulin-dependent protein kinase II on spontaneous neurotransmitter release in the squid giant synapse.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(21):8257-61.
1990: Richard Huganir; Paul Greengard
Regulation of neurotransmitter receptor desensitization by protein phosphorylation.
Neuron 1990;5(5):555-67.
1990: Alejandro M Bertorello; J F Hopfield; Anita Aperia; Paul Greengard
Inhibition by dopamine of (Na(+)+K+)ATPase activity in neostriatal neurons through D1 and D2 dopamine receptor synergism.
Nature 1990;347(6291):386-8.
1990: G Thiel; T C Südhof; Paul Greengard
Synapsin II. Mapping of a domain in the NH2-terminal region which binds to small synaptic vesicles.
The Journal of biological chemistry 1990;265(27):16527-33.
1990: B Berger; A Febvret; Paul Greengard; P S Goldman-Rakic
DARPP-32, a phosphoprotein enriched in dopaminoceptive neurons bearing dopamine D1 receptors: distribution in the cerebral cortex of the newborn and adult rhesus monkey.
The Journal of comparative neurology 1990;299(3):327-48.
1990: Juan C Sáez; Angus Nairn; A J Czernik; david spray; Elliot L Hertzberg; Paul Greengard; Michael V L Bennett
Phosphorylation of connexin 32, a hepatocyte gap-junction protein, by cAMP-dependent protein kinase, protein kinase C and Ca2+/calmodulin-dependent protein kinase II.
European journal of biochemistry / FEBS 1990;192(2):263-73.
1990: S Halpain; Paul Greengard
Activation of NMDA receptors induces rapid dephosphorylation of the cytoskeletal protein MAP2.
Neuron 1990;5(3):237-46.
1990: D Piomelli; Paul Greengard
Lipoxygenase metabolites of arachidonic acid in neuronal transmembrane signalling.
Trends in pharmacological sciences 1990;11(9):367-73.
1990: Joseph Buxbaum; Sam Gandy; P Cicchetti; M E Ehrlich; Andrew J Czernik; R P Fracasso; T V Ramabhadran; A J Unterbeck; Paul Greengard
Processing of Alzheimer beta/A4 amyloid precursor protein: modulation by agents that regulate protein phosphorylation.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(15):6003-6.
1990: Jean-Antoine Girault; S Halpain; Paul Greengard
Excitatory amino acid antagonists and Parkinson's disease.
Trends in neurosciences 1990;13(8):325-7.
1990: M M Sugrue; Joan S Brugge; D R Marshak; Paul Greengard; E L Gustafson
Immunocytochemical localization of the neuron-specific form of the c-src gene product, pp60c-src(+), in rat brain.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1990;10(8):2513-27.
1990: Fabio Benfenati; P Neyroz; M Bähler; Lanfranco Masotti; Paul Greengard
Time-resolved fluorescence study of the neuron-specific phosphoprotein synapsin I. Evidence for phosphorylation-dependent conformational changes.
The Journal of biological chemistry 1990;265(21):12584-95.
1990: J A Grebb; Jean-Antoine Girault; M Ehrlich; Paul Greengard
Chronic treatment of rats with SCH-23390 or raclopride does not affect the concentrations of DARPP-32 or its mRNA in dopamine-innervated brain regions.
Journal of neurochemistry 1990;55(1):204-7.
1990: James Mandell; E Townes-Anderson; A J Czernik; Richard S Cameron; Paul Greengard; Pietro De Camilli
Synapsins in the vertebrate retina: absence from ribbon synapses and heterogeneous distribution among conventional synapses.
Neuron 1990;5(1):19-33.
1990: M E Ehrlich; N L Rosen; T Kurihara; I A Shalaby; Paul Greengard
DARPP-32 development in the caudate nucleus is independent of afferent input from the substantia nigra.
Brain research. Developmental brain research 1990;54(2):257-63.
1990: A Horiuchi; Kenneth R Williams; T Kurihara; Angus Nairn; Paul Greengard
Purification and cDNA cloning of ARPP-16, a cAMP-regulated phosphoprotein enriched in basal ganglia, and of a related phosphoprotein, ARPP-19.
The Journal of biological chemistry 1990;265(16):9476-84.
1990: M Bähler; Fabio Benfenati; Flavia Valtorta; Paul Greengard
The synapsins and the regulation of synaptic function.
BioEssays : news and reviews in molecular, cellular and developmental biology 1990;12(6):259-63.
1990: Charles C Ouimet; J K Wang; S Ivar Walaas; K A Albert; Paul Greengard
Localization of the MARCKS (87 kDa) protein, a major specific substrate for protein kinase C, in rat brain.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1990;10(5):1683-98.
1990: Martin Schalling; A Dagerlind; M Goldstein; M Ehrlich; Paul Greengard; Tomas Hökfelt
Comparison of gene expression of the dopamine D-2 receptor and DARPP-32 in rat brain, pituitary and adrenal gland.
European journal of pharmacology 1990;188(4-5):277-81.
1990: Jean-Antoine Girault; A Horiuchi; E L Gustafson; N L Rosen; Paul Greengard
Differential expression of ARPP-16 and ARPP-19, two highly related cAMP-regulated phosphoproteins, one of which is specifically associated with dopamine-innervated brain regions.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1990;10(4):1124-33.
1990: Robert A Nichols; T S Sihra; Andrew J Czernik; Angus Nairn; Paul Greengard
Calcium/calmodulin-dependent protein kinase II increases glutamate and noradrenaline release from synaptosomes.
Nature 1990;343(6259):647-51.
1990: Charles C Ouimet; Paul Greengard
Distribution of DARPP-32 in the basal ganglia: an electron microscopic study.
Journal of neurocytology 1990;19(1):39-52.
1990: Martin Schalling; M Djurfeldt; Tomas Hökfelt; M Ehrlich; T Kurihara; Paul Greengard
Distribution and cellular localization of DARPP-32 mRNA in rat brain.
Brain research. Molecular brain research 1990;7(2):139-49.
1990: F Torri-Tarelli; A Villa; Flavia Valtorta; Pietro De Camilli; Paul Greengard; B Ceccarelli
Redistribution of synaptophysin and synapsin I during alpha-latrotoxin-induced release of neurotransmitter at the neuromuscular junction.
The Journal of cell biology 1990;110(2):449-59.
1990: S Halpain; Jean-Antoine Girault; Paul Greengard
Activation of NMDA receptors induces dephosphorylation of DARPP-32 in rat striatal slices.
Nature 1990;343(6256):369-72.
1990: Pietro De Camilli; Fabio Benfenati; F Valtorta; Paul Greengard
The synapsins.
Annual review of cell biology 1990;6():433-60.
1990: M E Ehrlich; T Kurihara; Paul Greengard
Rat DARPP-32: cloning, sequencing, and characterization of the cDNA.
Journal of molecular neuroscience : MN 1990;2(1):1-10.
1990: E L Gustafson; Paul Greengard
Localization of DARPP-32 immunoreactive neurons in the bed nucleus of the stria terminalis and central nucleus of the amygdala: co-distribution with axons containing tyrosine hydroxylase, vasoactive intestinal polypeptide, and calcitonin gene-related peptide.
Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale 1990;79(3):447-58.
1990: Jean-Antoine Girault; S Ivar Walaas; Hugh C Hemmings; Paul Greengard
ARPP-21, a cAMP-regulated phosphoprotein enriched in dopamine-innervated brain regions: tissue distribution and regulation of phosphorylation in rat brain.
Neuroscience 1990;37(2):317-25.
1989: Jean-Antoine Girault; Hugh C Hemmings; Kenneth R Williams; Angus Nairn; Paul Greengard
Phosphorylation of DARPP-32, a dopamine- and cAMP-regulated phosphoprotein, by casein kinase II.
The Journal of biological chemistry 1989;264(36):21748-59.
1989: Flavia Valtorta; F T Tarelli; L Campanati; A Villa; Paul Greengard
Synaptophysin and synapsin I as tools for the study of the exo-endocytotic cycle.
Cell biology international reports 1989;13(12):1023-38.
1989: Fabio Benfenati; Flavia Valtorta; M Bähler; Paul Greengard
Synapsin I, a neuron-specific phosphoprotein interacting with small synaptic vesicles and F-actin.
Cell biology international reports 1989;13(12):1007-21.
1989: F Navone; G Di Gioia; R Jahn; M Browning; Paul Greengard; Pietro De Camilli
Microvesicles of the neurohypophysis are biochemically related to small synaptic vesicles of presynaptic nerve terminals.
The Journal of cell biology 1989;109(6 Pt 2):3425-33.
1989: T L McGuinness; Scott T Brady; John Gruner; Mutsuyuki Sugimori; R Llinas; Paul Greengard
Phosphorylation-dependent inhibition by synapsin I of organelle movement in squid axoplasm.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1989;9(12):4138-49.
1989: Björn Meister; Marcelo J Villar; Martin Schalling; M Ehrlich; Paul Greengard; Tomas Hökfelt
Demonstration of DARPP-32 in pituicytes of the neurohypophysis-decreased expression after administration of hyperosmotic stimuli.
Acta physiologica Scandinavica 1989;137(3):461-2.
1989: Lisa Won; S Price; B H Wainer; P C Hoffmann; J P Bolam; Paul Greengard; Alfred Heller
Correlated light and electron microscopic study of dopaminergic neurons and their synaptic junctions with DARPP-32-containing cells in three-dimensional reaggregate tissue culture.
The Journal of comparative neurology 1989;289(1):165-77.
1989: D Piomelli; J K Wang; T S Sihra; Angus Nairn; Andrew J Czernik; Paul Greengard
Inhibition of Ca2+/calmodulin-dependent protein kinase II by arachidonic acid and its metabolites.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(21):8550-4.
1989: S Ivar Walaas; J K Wang; K A Albert; Paul Greengard
Calcium/diacylglycerol-dependent protein kinase and its major 87-kilodalton protein substrate are differentially distributed in rat basal ganglia.
Journal of neurochemistry 1989;53(4):1199-202.
1989: J A Grebb; M D Browning; P Valverius; S Borg; G Sedvall; Paul Greengard
An analysis of postmortem brain samples from 32 alcoholic and nonalcoholic individuals for protein III, a neuronal phosphoprotein.
Alcoholism, clinical and experimental research 1989;13(5):673-9.
1989: Björn Meister; J Fryckstedt; Martin Schalling; R Cortés; Tomas Hökfelt; Anita Aperia; H C Hemmings; Angus Nairn; M Ehrlich; Paul Greengard
Dopamine- and cAMP-regulated phosphoprotein (DARPP-32) and dopamine DA1 agonist-sensitive Na+,K+-ATPase in renal tubule cells.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(20):8068-72.
1989: T Kurihara; M E Ehrlich; J Horiuchi; T Nasu; Paul Greengard
ARPP-21, a cyclic AMP-regulated phosphoprotein enriched in dopamine-innervated brain regions. II. Molecular cloning and nucleotide sequence.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1989;9(10):3638-44.
1989: Kenneth R Williams; Hugh C Hemmings; M B LoPresti; Paul Greengard
ARPP-21, a cyclic AMP-regulated phosphoprotein enriched in dopamine-innervated brain regions. I. Amino acid sequence of ARPP-21B from bovine caudate nucleus.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1989;9(10):3631-7.
1989: T S Sihra; J K Wang; F S Gorelick; Paul Greengard
Translocation of synapsin I in response to depolarization of isolated nerve terminals.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(20):8108-12.
1989: J A Girault; F S Gorelick; Paul Greengard
Improving the quality of immunoblots by chromatography of polyclonal antisera on keratin affinity columns.
Analytical biochemistry 1989;182(1):193-6.
1989: A Bahinski; Angus Nairn; Paul Greengard; David C Gadsby
Chloride conductance regulated by cyclic AMP-dependent protein kinase in cardiac myocytes.
Nature 1989;340(6236):718-21.
1989: E L Gustafson; Charles C Ouimet; Paul Greengard
Spatial relationship of the striatonigral and mesostriatal pathways: double-label immunocytochemistry for DARPP-32 and tyrosine hydroxylase.
Brain research 1989;491(2):297-306.
1989: M Li; J D McCann; Matthew Peter Anderson; J P Clancy; C M Liedtke; Angus Nairn; Paul Greengard; M J Welsch
Regulation of chloride channels by protein kinase C in normal and cystic fibrosis airway epithelia.
Science (New York, N.Y.) 1989;244(4910):1353-6.
1989: A Rosen; Angus Nairn; Paul Greengard; Z A Cohn; Alan Aderem
Bacterial lipopolysaccharide regulates the phosphorylation of the 68K protein kinase C substrate in macrophages.
The Journal of biological chemistry 1989;264(16):9118-21.
1989: Deborah J Stumpo; Jonathan M Graff; K A Albert; Paul Greengard; Perry Blackshear
Molecular cloning, characterization, and expression of a cDNA encoding the "80- to 87-kDa" myristoylated alanine-rich C kinase substrate: a major cellular substrate for protein kinase C.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(11):4012-6.
1989: Ken Mackie; B C Sorkin; Angus Nairn; Paul Greengard; Gerald M Edelman; Bruce A Cunningham
Identification of two protein kinases that phosphorylate the neural cell-adhesion molecule, N-CAM.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1989;9(6):1883-96.
1989: Deborah J Stumpo; Jonathan M Graff; K A Albert; Paul Greengard; Perry Blackshear
Nucleotide sequence of a cDNA for the bovine myristoylated alanine-rich C kinase substrate (MARCKS).
Nucleic acids research 1989;17(10):3987-8.
1989: Hugh C Hemmings; Jean-Antoine Girault; Kenneth R Williams; M B LoPresti; Paul Greengard
ARPP-21, a cyclic AMP-regulated phosphoprotein (Mr = 21,000) enriched in dopamine-innervated brain regions. Amino acid sequence of the site phosphorylated by cyclic AMP in intact cells and kinetic studies of its phosphorylation in vitro.
The Journal of biological chemistry 1989;264(13):7726-33.
1989: K Miles; Paul Greengard; Richard Huganir
Calcitonin gene-related peptide regulates phosphorylation of the nicotinic acetylcholine receptor in rat myotubes.
Neuron 1989;2(5):1517-24.
1989: Fabio Benfenati; M Bähler; R Jahn; Paul Greengard
Interactions of synapsin I with small synaptic vesicles: distinct sites in synapsin I bind to vesicle phospholipids and vesicle proteins.
The Journal of cell biology 1989;108(5):1863-72.
1989: Fabio Benfenati; Paul Greengard; J Brunner; M Bähler
Electrostatic and hydrophobic interactions of synapsin I and synapsin I fragments with phospholipid bilayers.
The Journal of cell biology 1989;108(5):1851-62.
1989: M Bähler; Fabio Benfenati; Flavia Valtorta; Andrew J Czernik; Paul Greengard
Characterization of synapsin I fragments produced by cysteine-specific cleavage: a study of their interactions with F-actin.
The Journal of cell biology 1989;108(5):1841-9.
1989: Jean-Antoine Girault; Rita Raisman-Vozari; Yves Agid; Paul Greengard
Striatal phosphoproteins in Parkinson disease and progressive supranuclear palsy.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(7):2493-7.
1989: J K Wang; S Ivar Walaas; T S Sihra; Alan Aderem; Paul Greengard
Phosphorylation and associated translocation of the 87-kDa protein, a major protein kinase C substrate, in isolated nerve terminals.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(7):2253-6.
1989: S I Walaas; S Cala; Paul Greengard
Localization of ARPP-90, a major 90 kiloDalton basal ganglion-enriched substrate for cyclic AMP-dependent protein kinase, in striatonigral neurons in the rat brain.
Brain research. Molecular brain research 1989;5(2):149-57.
1989: P Strålfors; H C Hemmings; Paul Greengard
Inhibitors of protein phosphatase-1. Inhibitor-1 of bovine adipose tissue and a dopamine- and cAMP-regulated phosphoprotein of bovine brain are identical.
European journal of biochemistry / FEBS 1989;180(1):143-8.
1989: Charles C Ouimet; Hugh C Hemmings; Paul Greengard
ARPP-21, a cyclic AMP-regulated phosphoprotein enriched in dopamine-innervated brain regions. II. Immunocytochemical localization in rat brain.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1989;9(3):865-75.
1989: Hugh C Hemmings; Paul Greengard
ARPP-21, a cyclic AMP-regulated phosphoprotein enriched in dopamine-innervated brain regions. I. Purification and characterization of the protein from bovine caudate nucleus.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1989;9(3):851-64.
1989: Hugh C Hemmings; Angus Nairn; T L McGuinness; Richard Huganir; Paul Greengard
Role of protein phosphorylation in neuronal signal transduction.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1989;3(5):1583-92.
1989: P J Conn; J A Strong; E M Azhderian; Angus Nairn; Paul Greengard; Leonard K Kaczmarek
Protein kinase inhibitors selectively block phorbol ester- or forskolin-induced changes in excitability of Aplysia neurons.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1989;9(2):473-9.
1989: Robert A Nichols; W C Wu; J W Haycock; Paul Greengard
Introduction of impermeant molecules into synaptosomes using freeze/thaw permeabilization.
Journal of neurochemistry 1989;52(2):521-9.
1989: S Ivar Walaas; E Perdahl-Wallace; Bengt Winblad; Paul Greengard
Protein phosphorylation systems in postmortem human brain.
Journal of molecular neuroscience : MN 1989;1(2):105-16.
1989: S Ivar Walaas; Jean-Antoine Girault; Paul Greengard
Localization of cyclic GMP-dependent protein kinase in rat basal ganglia neurons.
Journal of molecular neuroscience : MN 1989;1(4):243-50.
1989: S Ivar Walaas; F S Gorelick; Paul Greengard
Presence of calcium/calmodulin-dependent protein kinase II in nerve terminals of rat brain.
Synapse (New York, N.Y.) 1989;3(4):356-62.
1989: S Ivar Walaas; G Sedvall; Paul Greengard
Dopamine-regulated phosphorylation of synaptic vesicle-associated proteins in rat neostriatum and substantia nigra.
Neuroscience 1989;29(1):9-19.
1988: J F Hopfield; D W Tank; Paul Greengard; Richard Huganir
Functional modulation of the nicotinic acetylcholine receptor by tyrosine phosphorylation.
Nature 1988;336(6200):677-80.
1988: Flavia Valtorta; R Jahn; R Fesce; Paul Greengard; B Ceccarelli
Synaptophysin (p38) at the frog neuromuscular junction: its incorporation into the axolemma and recycling after intense quantal secretion.
The Journal of cell biology 1988;107(6 Pt 2):2717-27.
1988: Luigi F Agnati; Kjell Fuxe; Michele Zoli; F Ferraguti; F Benfenati; Charles C Ouimet; S Ivar Walaas; Hugh C Hemmings; M Goldstein; Paul Greengard
Morphometrical evidence for a complex organization of tyrosine hydroxylase-, enkephalin- and DARPP-32-like immunoreactive patches and their codistribution at three rostrocaudal levels in the rat neostriatum.
Neuroscience 1988;27(3):785-97.
1988: F S Gorelick; J K Wang; Y Lai; Angus Nairn; Paul Greengard
Autophosphorylation and activation of Ca2+/calmodulin-dependent protein kinase II in intact nerve terminals.
The Journal of biological chemistry 1988;263(33):17209-12.
1988: Björn Meister; Tomas Hökfelt; Y Tsuruo; H Hemmings; C Ouimet; Paul Greengard; M Goldstein
DARPP-32, a dopamine- and cyclic AMP-regulated phosphoprotein in tanycytes of the mediobasal hypothalamus: distribution and relation to dopamine and luteinizing hormone-releasing hormone neurons and other glial elements.
Neuroscience 1988;27(2):607-22.
1988: S Ivar Walaas; Y Lai; F S Gorelick; Pietro De Camilli; M Moretti; Paul Greengard
Cell-specific localization of the alpha-subunit of calcium/calmodulin-dependent protein kinase II in Purkinje cells in rodent cerebellum.
Brain research 1988;464(3):233-42.
1988: Björn Meister; G Fried; Tomas Hökfelt; H C Hemmings; Paul Greengard
Immunohistochemical evidence for the existence of a dopamine- and cyclic AMP-regulated phosphoprotein (DARPP-32) in brown adipose tissue of pigs.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(22):8713-6.
1988: S Ivar Walaas; M D Browning; Paul Greengard
Synapsin Ia, synapsin Ib, protein IIIa, and protein IIIb, four related synaptic vesicle-associated phosphoproteins, share regional and cellular localization in rat brain.
Journal of neurochemistry 1988;51(4):1214-20.
1988: Jean-Antoine Girault; I A Shalaby; N L Rosen; Paul Greengard
Regulation by cAMP and vasoactive intestinal peptide of phosphorylation of specific proteins in striatal cells in culture.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(20):7790-4.
1988: J W Haycock; Paul Greengard; M D Browning
Cholinergic regulation of protein III phosphorylation in bovine adrenal chromaffin cells.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1988;8(9):3233-9.
1988: G Thiel; Andrew J Czernik; F Gorelick; Angus Nairn; Paul Greengard
Ca2+/calmodulin-dependent protein kinase II: identification of threonine-286 as the autophosphorylation site in the alpha subunit associated with the generation of Ca2+-independent activity.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(17):6337-41.
1988: Sam Gandy; Andrew J Czernik; Paul Greengard
Phosphorylation of Alzheimer disease amyloid precursor peptide by protein kinase C and Ca2+/calmodulin-dependent protein kinase II.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(16):6218-21.
1988: S Ivar Walaas; A Lustig; Paul Greengard; Joan S Brugge
Widespread distribution of the c-src gene product in nerve cells and axon terminals in the adult rat brain.
Brain research 1988;427(3):215-22.
1988: A A Hirano; Paul Greengard; Richard Huganir
Protein tyrosine kinase activity and its endogenous substrates in rat brain: a subcellular and regional survey.
Journal of neurochemistry 1988;50(5):1447-55.
1988: S M Audigier; J K Wang; Paul Greengard
Membrane depolarization and carbamoylcholine stimulate phosphatidylinositol turnover in intact nerve terminals.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(8):2859-63.
1988: Alan Aderem; K A Albert; M M Keum; J K Wang; Paul Greengard; Z A Cohn
Stimulus-dependent myristoylation of a major substrate for protein kinase C.
Nature 1988;332(6162):362-4.
1988: J W Haycock; M D Browning; Paul Greengard
Cholinergic regulation of protein phosphorylation in bovine adrenal chromaffin cells.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(5):1677-81.
1988: T Kurihara; R M Lewis; J Eisler; Paul Greengard
Cloning of cDNA for DARPP-32, a dopamine- and cyclic AMP-regulated neuronal phosphoprotein.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1988;8(2):508-17.
1988: Flavia Valtorta; A Villa; R Jahn; Pietro De Camilli; Paul Greengard; B Ceccarelli
Localization of synapsin I at the frog neuromuscular junction.
Neuroscience 1988;24(2):593-603.
1988: D T Pang; J K Wang; Flavia Valtorta; Fabio Benfenati; Paul Greengard
Protein tyrosine phosphorylation in synaptic vesicles.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(3):762-6.
1988: M Li; J D McCann; C M Liedtke; Angus Nairn; Paul Greengard; Michael J Welsh
Cyclic AMP-dependent protein kinase opens chloride channels in normal but not cystic fibrosis airway epithelium.
Nature 1988;331(6154):358-60.
1988: Angus Nairn; Hugh C Hemmings; S Ivar Walaas; Paul Greengard
DARPP-32 and phosphatase inhibitor-1, two structurally related inhibitors of protein phosphatase-1, are both present in striatonigral neurons.
Journal of neurochemistry 1988;50(1):257-62.
1988: J K Wang; S Ivar Walaas; Paul Greengard
Protein phosphorylation in nerve terminals: comparison of calcium/calmodulin-dependent and calcium/diacylglycerol-dependent systems.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1988;8(1):281-8.
1988: S Ivar Walaas; R Jahn; Paul Greengard
Quantitation of nerve terminal populations: synaptic vesicle-associated proteins as markers for synaptic density in the rat neostriatum.
Synapse (New York, N.Y.) 1988;2(5):516-20.
1988: Paul Greengard; M D Browning
Studies of the physiological role of specific neuronal phosphoproteins.
Advances in second messenger and phosphoprotein research 1988;21():133-46.
1988: Charles C Ouimet; Hugh C Hemmings; Paul Greengard
Dopamine-regulated protein phosphorylation in the basal ganglia.
Advances in experimental medicine and biology 1988;235():1-17.
1988: Tomas Hökfelt; G Foster; M Schultzberg; Björn Meister; Martin Schalling; M Goldstein; H C Hemmings; Charles C Ouimet; Paul Greengard
DARPP-32 as a marker for D-1 dopaminoceptive cells in the rat brain: prenatal development and presence in glial elements (tanycytes) in the basal hypothalamus.
Advances in experimental medicine and biology 1988;235():65-82.
1988: A J Friedhoff; DAVID PICKAR; Julius Axelrod; I Creese; Kenneth L Davis; D W Gallagher; Paul Greengard; D Housman; J W Maas; E Richelson
Neurochemistry and neuropharmacology.
Schizophrenia bulletin 1988;14(3):399-412.
1988: G A Foster; M Schultzberg; T Kökfelt; M Goldstein; Hugh C Hemmings; Charles C Ouimet; S Ivar Walaas; Paul Greengard
Ontogeny of the dopamine and cyclic adenosine-3':5'-monophosphate-regulated phosphoprotein (DARPP-32) in the pre- and postnatal mouse central nervous system.
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 1988;6(4):367-86.
1988: G Weeks; Marina R Picciotto; Angus Nairn; S Ivar Walaas; Paul Greengard
Purification and characterization of PCPP-260: a Purkinje cell-enriched cyclic AMP-regulated membrane phosphoprotein of Mr 260,000.
Synapse (New York, N.Y.) 1988;2(1):89-96.
1987: Thomas C Südhof; F Lottspeich; Paul Greengard; E Mehl; Reinhard Jahn
The cDNA and derived amino acid sequences for rat and human synaptophysin.
Nucleic acids research 1987;15(22):9607.
1987: Thomas C Südhof; F Lottspeich; Paul Greengard; E Mehl; Reinhard Jahn
A synaptic vesicle protein with a novel cytoplasmic domain and four transmembrane regions.
Science (New York, N.Y.) 1987;238(4830):1142-4.
1987: Andrew J Czernik; D T Pang; Paul Greengard
Amino acid sequences surrounding the cAMP-dependent and calcium/calmodulin-dependent phosphorylation sites in rat and bovine synapsin I.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(21):7518-22.
1987: K A Albert; Angus Nairn; Paul Greengard
The 87-kDa protein, a major specific substrate for protein kinase C: purification from bovine brain and characterization.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(20):7046-50.
1987: K Miles; D T Anthony; L L Rubin; Paul Greengard; Richard Huganir
Regulation of nicotinic acetylcholine receptor phosphorylation in rat myotubes by forskolin and cAMP.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(18):6591-5.
1987: Y Lai; Angus Nairn; F Gorelick; Paul Greengard
Ca2+/calmodulin-dependent protein kinase II: identification of autophosphorylation sites responsible for generation of Ca2+/calmodulin-independence.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(16):5710-4.
1987: G Y Hu; Oivind Hvalby; S I Walaas; K A Albert; P Skjeflo; P Andersen; Paul Greengard
Protein kinase C injection into hippocampal pyramidal cells elicits features of long term potentiation.
Nature 1987;328(6129):426-9.
1987: Nancy E Thomas; H N Bramson; Angus Nairn; Paul Greengard; D C Fry; A S Mildvan; E T Kaiser
Distinguishing among protein kinases by substrate specificities.
Biochemistry 1987;26(14):4471-4.
1987: G A Foster; M Schultzberg; T Hökfelt; M Goldstein; Hugh C Hemmings; Charles C Ouimet; S Ivar Walaas; Paul Greengard
Development of a dopamine- and cyclic adenosine 3':5'-monophosphate-regulated phosphoprotein (DARPP-32) in the prenatal rat central nervous system, and its relationship to the arrival of presumptive dopaminergic innervation.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1987;7(7):1994-2018.
1987: T P Parks; Angus Nairn; Paul Greengard; J D Jamieson
The cyclic nucleotide-dependent phosphorylation of aortic smooth muscle membrane proteins.
Archives of biochemistry and biophysics 1987;255(2):361-71.
1987: Angus Nairn; Paul Greengard
Purification and characterization of Ca2+/calmodulin-dependent protein kinase I from bovine brain.
The Journal of biological chemistry 1987;262(15):7273-81.
1987: Carmelo Romano; R A Nichols; Paul Greengard; L A Greene
Synapsin I in PC12 cells. I. Characterization of the phosphoprotein and effect of chronic NGF treatment.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1987;7(5):1294-9.
1987: Carmelo Romano; R A Nichols; Paul Greengard
Synapsin I in PC12 cells. II. Evidence for regulation by NGF of phosphorylation at a novel site.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1987;7(5):1300-6.
1987: M Bähler; Paul Greengard
Synapsin I bundles F-actin in a phosphorylation-dependent manner.
Nature 1987;326(6114):704-7.
1987: M D Browning; C K Huang; Paul Greengard
Similarities between protein IIIa and protein IIIb, two prominent synaptic vesicle-associated phosphoproteins.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1987;7(3):847-53.
1987: Paul Greengard
Neuronal phosphoproteins. Mediators of signal transduction.
Molecular neurobiology 1987;1(1-2):81-119.
1987: C Hammond; D Paupardin-Tritsch; Angus Nairn; Paul Greengard; H M Gerschenfeld
Cholecystokinin induces a decrease in Ca2+ current in snail neurons that appears to be mediated by protein kinase C.
Nature 1987;325(6107):809-11.
1987: Robert A Nichols; J W Haycock; J K Wang; Paul Greengard
Phorbol ester enhancement of neurotransmitter release from rat brain synaptosomes.
Journal of neurochemistry 1987;48(2):615-21.
1987: Paul Greengard; M D Browning; T L McGuinness; R Llinas
Synapsin I, a phosphoprotein associated with synaptic vesicles: possible role in regulation of neurotransmitter release.
Advances in experimental medicine and biology 1987;221():135-53.
1986: Pietro De Camilli; Paul Greengard
Synapsin I: a synaptic vesicle-associated neuronal phosphoprotein.
Biochemical pharmacology 1986;35(24):4349-57.
1986: F Navone; R Jahn; G Di Gioia; H Stukenbrok; Paul Greengard; Pietro De Camilli
Protein p38: an integral membrane protein specific for small vesicles of neurons and neuroendocrine cells.
The Journal of cell biology 1986;103(6 Pt 1):2511-27.
1986: R A Stone; A M Laties; Hugh C Hemmings; Charles C Ouimet; Paul Greengard
DARPP-32 in the ciliary epithelium of the eye: a neurotransmitter-regulated phosphoprotein of brain localizes to secretory cells.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 1986;34(11):1465-8.
1986: D Paupardin-Tritsch; C Hammond; H M Gerschenfeld; Angus Nairn; Paul Greengard
cGMP-dependent protein kinase enhances Ca2+ current and potentiates the serotonin-induced Ca2+ current increase in snail neurones.
Nature 1986;323(6091):812-4.
1986: Flavia Valtorta; W Schiebler; R Jahn; B Ceccarelli; Paul Greengard
A solid-phase assay for the phosphorylation of proteins blotted on nitrocellulose membrane filters.
Analytical biochemistry 1986;158(1):130-7.
1986: Ken Mackie; Y Lai; Angus Nairn; Paul Greengard; Bruce R Pitt; John Lazo
Protein phosphorylation in cultured endothelial cells.
Journal of cellular physiology 1986;128(3):367-74.
1986: W Schiebler; R Jahn; J P Doucet; Joan Rothlein; Paul Greengard
Characterization of synapsin I binding to small synaptic vesicles.
The Journal of biological chemistry 1986;261(18):8383-90.
1986: Richard Huganir; A H Delcour; Paul Greengard; George P Hess
Phosphorylation of the nicotinic acetylcholine receptor regulates its rate of desensitization.
Nature 1986;321(6072):774-6.
1986: Y Lai; Angus Nairn; Paul Greengard
Autophosphorylation reversibly regulates the Ca2+/calmodulin-dependence of Ca2+/calmodulin-dependent protein kinase II.
Proceedings of the National Academy of Sciences of the United States of America 1986;83(12):4253-7.
1986: H C Hemmings; Paul Greengard
DARPP-32, a dopamine- and adenosine 3':5'-monophosphate-regulated phosphoprotein: regional, tissue, and phylogenetic distribution.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1986;6(5):1469-81.
1986: K A Albert; S Ivar Walaas; J K Wang; Paul Greengard
Widespread occurrence of "87 kDa," a major specific substrate for protein kinase C.
Proceedings of the National Academy of Sciences of the United States of America 1986;83(9):2822-6.
1986: J C Saez; david spray; Angus Nairn; E Hertzberg; Paul Greengard; Michael V L Bennett
cAMP increases junctional conductance and stimulates phosphorylation of the 27-kDa principal gap junction polypeptide.
Proceedings of the National Academy of Sciences of the United States of America 1986;83(8):2473-7.
1986: S I Walaas; Angus Nairn; Paul Greengard
PCPP-260, a Purkinje cell-specific cyclic AMP-regulated membrane phosphoprotein of Mr 260,000.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1986;6(4):954-61.
1986: Kenneth R Williams; Hugh C Hemmings; M B LoPresti; W H Konigsberg; Paul Greengard
DARPP-32, a dopamine- and cyclic AMP-regulated neuronal phosphoprotein. Primary structure and homology with protein phosphatase inhibitor-1.
The Journal of biological chemistry 1986;261(4):1890-903.
1986: H C Hemmings; Paul Greengard
DARPP-32, a dopamine-regulated phosphoprotein.
Progress in brain research 1986;69():149-59.
1986: Eric J Nestler; Paul Greengard
Synapsin I: a review of its distribution and biological regulation.
Progress in brain research 1986;69():323-39.
1986: H C Hemmings; Angus Nairn; Paul Greengard
Protein kinases and phosphoproteins in the nervous system.
Research publications - Association for Research in Nervous and Mental Disease 1986;64():47-69.
1985: Susan A DeRiemer; Paul Greengard; L K Kaczmarek
Calcium/phosphatidylserine/diacylglycerol-dependent protein phosphorylation in the Aplysia nervous system.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1985;5(10):2672-6.
1985: S E Goelz; Eric J Nestler; Paul Greengard
Phylogenetic survey of proteins related to synapsin I and biochemical analysis of four such proteins from fish brain.
Journal of neurochemistry 1985;45(1):63-72.
1985: M D Browning; Richard Huganir; Paul Greengard
Protein phosphorylation and neuronal function.
Journal of neurochemistry 1985;45(1):11-23.
1985: M Treiman; Paul Greengard
D-1 and D-2 dopaminergic receptors regulate protein phosphorylation in the rat neurohypophysis.
Neuroscience 1985;15(3):713-22.
1985: R Jahn; W Schiebler; C Ouimet; Paul Greengard
A 38,000-dalton membrane protein (p38) present in synaptic vesicles.
Proceedings of the National Academy of Sciences of the United States of America 1985;82(12):4137-41.
1985: R Llinás; T L McGuinness; C S Leonard; Mutsuyuki Sugimori; Paul Greengard
Intraterminal injection of synapsin I or calcium/calmodulin-dependent protein kinase II alters neurotransmitter release at the squid giant synapse.
Proceedings of the National Academy of Sciences of the United States of America 1985;82(9):3035-9.
1985: T L McGuinness; Y Lai; Paul Greengard
Ca2+/calmodulin-dependent protein kinase II. Isozymic forms from rat forebrain and cerebellum.
The Journal of biological chemistry 1985;260(3):1696-704.
1985: P Mobley; Paul Greengard
Evidence for widespread effects of noradrenaline on axon terminals in the rat frontal cortex.
Proceedings of the National Academy of Sciences of the United States of America 1985;82(3):945-7.
1985: Susan A DeRiemer; J A Strong; K A Albert; Paul Greengard; L K Kaczmarek
Enhancement of calcium current in Aplysia neurones by phorbol ester and protein kinase C.
Nature 1985;313(6000):313-6.
1985: Angus Nairn; H C Hemmings; Paul Greengard
Protein kinases in the brain.
Annual review of biochemistry 1985;54():931-76.
1984: H C Hemmings; Angus Nairn; Paul Greengard
DARPP-32, a dopamine- and adenosine 3':5'-monophosphate-regulated neuronal phosphoprotein. II. Comparison of the kinetics of phosphorylation of DARPP-32 and phosphatase inhibitor 1.
The Journal of biological chemistry 1984;259(23):14491-7.
1984: H C Hemmings; K R Williams; W H Konigsberg; Paul Greengard
DARPP-32, a dopamine- and adenosine 3':5'-monophosphate-regulated neuronal phosphoprotein. I. Amino acid sequence around the phosphorylated threonine.
The Journal of biological chemistry 1984;259(23):14486-90.
1984: F Navone; Paul Greengard; Pietro De Camilli
Synapsin I in nerve terminals: selective association with small synaptic vesicles.
Science (New York, N.Y.) 1984;226(4679):1209-11.
1984: K A Albert; E Helmer-Matyjek; Angus Nairn; T H Müller; J W Haycock; L A Greene; M Goldstein; Paul Greengard
Calcium/phospholipid-dependent protein kinase (protein kinase C) phosphorylates and activates tyrosine hydroxylase.
Proceedings of the National Academy of Sciences of the United States of America 1984;81(24):7713-7.
1984: Richard Huganir; K Miles; Paul Greengard
Phosphorylation of the nicotinic acetylcholine receptor by an endogenous tyrosine-specific protein kinase.
Proceedings of the National Academy of Sciences of the United States of America 1984;81(22):6968-72.
1984: E Perdahl; W C Wu; M D Browning; Bengt Winblad; Paul Greengard
Protein III, a neuron-specific phosphoprotein: variant forms found in human brain.
Neurobehavioral toxicology and teratology 1984;6(6):425-31.
1984: J A Detre; Angus Nairn; D W Aswad; Paul Greengard
Localization in mammalian brain of G-substrate, a specific substrate for guanosine 3',5'-cyclic monophosphate-dependent protein kinase.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1984;4(11):2843-9.
1984: Pat Levitt; P Rakic; Pietro De Camilli; Paul Greengard
Emergence of cyclic guanosine 3':5'-monophosphate-dependent protein kinase immunoreactivity in developing rhesus monkey cerebellum: correlative immunocytochemical and electron microscopic analysis.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1984;4(10):2553-64.
1984: Eric J Nestler; S I Walaas; Paul Greengard
Neuronal phosphoproteins: physiological and clinical implications.
Science (New York, N.Y.) 1984;225(4668):1357-64.
1984: C C Ouimet; T L McGuinness; Paul Greengard
Immunocytochemical localization of calcium/calmodulin-dependent protein kinase II in rat brain.
Proceedings of the National Academy of Sciences of the United States of America 1984;81(17):5604-8.
1984: H C Hemmings; Paul Greengard; H Y Tung; P Cohen
DARPP-32, a dopamine-regulated neuronal phosphoprotein, is a potent inhibitor of protein phosphatase-1.
Nature 1984;310(5977):503-5.
1984: M M King; C Y Huang; P B Chock; Angus Nairn; H C Hemmings; K F Chan; Paul Greengard
Mammalian brain phosphoproteins as substrates for calcineurin.
The Journal of biological chemistry 1984;259(13):8080-3.
1984: Susan A DeRiemer; L K Kaczmarek; Y Lai; T L McGuinness; Paul Greengard
Calcium/calmodulin-dependent protein phosphorylation in the nervous system of Aplysia.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1984;4(6):1618-25.
1984: K A Albert; W C Wu; Angus Nairn; Paul Greengard
Inhibition by calmodulin of calcium/phospholipid-dependent protein phosphorylation.
Proceedings of the National Academy of Sciences of the United States of America 1984;81(12):3622-5.
1984: Pietro De Camilli; P E Miller; Pat Levitt; U Walter; Paul Greengard
Anatomy of cerebellar Purkinje cells in the rat determined by a specific immunohistochemical marker.
Neuroscience 1984;11(4):761-817.
1984: R Jahn; W Schiebler; Paul Greengard
A quantitative dot-immunobinding assay for proteins using nitrocellulose membrane filters.
Proceedings of the National Academy of Sciences of the United States of America 1984;81(6):1684-7.
1984: P T Kelly; T L McGuinness; Paul Greengard
Evidence that the major postsynaptic density protein is a component of a Ca2+/calmodulin-dependent protein kinase.
Proceedings of the National Academy of Sciences of the United States of America 1984;81(3):945-9.
1984: H C Palfrey; Y Lai; Paul Greengard
Calmodulin-dependent protein kinase from avian erythrocytes.
Progress in clinical and biological research 1984;165():291-308.
1984: E Perdahl; R Adolfsson; Irina Alafuzoff; K A Albert; Eric J Nestler; Paul Greengard; Bengt Winblad
Synapsin I (protein I) in different brain regions in senile dementia of Alzheimer type and in multi-infarct dementia.
Journal of neural transmission 1984;60(2):133-41.
1984: Eric J Nestler; Paul Greengard
Neuron-specific phosphoproteins in mammalian brain.
Advances in cyclic nucleotide and protein phosphorylation research 1984;17():483-8.
1984: H C Hemmings; Angus Nairn; D W Aswad; Paul Greengard
DARPP-32, a dopamine- and adenosine 3':5'-monophosphate-regulated phosphoprotein enriched in dopamine-innervated brain regions. II. Purification and characterization of the phosphoprotein from bovine caudate nucleus.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1984;4(1):99-110.
1984: S I Walaas; Paul Greengard
DARPP-32, a dopamine- and adenosine 3':5'-monophosphate-regulated phosphoprotein enriched in dopamine-innervated brain regions. I. Regional and cellular distribution in the rat brain.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1984;4(1):84-98.
1984: Charles C Ouimet; P E Miller; Hugh C Hemmings; S Ivar Walaas; Paul Greengard
DARPP-32, a dopamine- and adenosine 3':5'-monophosphate-regulated phosphoprotein enriched in dopamine-innervated brain regions. III. Immunocytochemical localization.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1984;4(1):111-24.
1983: T L McGuinness; Y Lai; Paul Greengard; J R Woodgett; P Cohen
A multifunctional calmodulin-dependent protein kinase. Similarities between skeletal muscle glycogen synthase kinase and a brain synapsin I kinase.
FEBS letters 1983;163(2):329-34.
1983: Angus Nairn; Paul Greengard
Cyclic GMP-dependent protein phosphorylation in mammalian brain.
Federation proceedings 1983;42(14):3107-13.
1983: Eric J Nestler; Paul Greengard
Protein phosphorylation in the brain.
Nature 1983;305(5935):583-8.
1983: H C Palfrey; Joan Rothlein; Paul Greengard
Calmodulin-dependent protein kinase and associated substrates in Torpedo electric organ.
The Journal of biological chemistry 1983;258(15):9496-503.
1983: D W Tank; Richard Huganir; Paul Greengard; W W Webb
Patch-recorded single-channel currents of the purified and reconstituted Torpedo acetylcholine receptor.
Proceedings of the National Academy of Sciences of the United States of America 1983;80(16):5129-33.
1983: W B Huttner; W Schiebler; Paul Greengard; Pietro De Camilli
Synapsin I (protein I), a nerve terminal-specific phosphoprotein. III. Its association with synaptic vesicles studied in a highly purified synaptic vesicle preparation.
The Journal of cell biology 1983;96(5):1374-88.
1983: Pietro De Camilli; S M Harris; W B Huttner; Paul Greengard
Synapsin I (Protein I), a nerve terminal-specific phosphoprotein. II. Its specific association with synaptic vesicles demonstrated by immunocytochemistry in agarose-embedded synaptosomes.
The Journal of cell biology 1983;96(5):1355-73.
1983: Pietro De Camilli; Richard S Cameron; Paul Greengard
Synapsin I (protein I), a nerve terminal-specific phosphoprotein. I. Its general distribution in synapses of the central and peripheral nervous system demonstrated by immunofluorescence in frozen and plastic sections.
The Journal of cell biology 1983;96(5):1337-54.
1983: M B Kennedy; T McGuinness; Paul Greengard
A calcium/calmodulin-dependent protein kinase from mammalian brain that phosphorylates Synapsin I: partial purification and characterization.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1983;3(4):818-31.
1983: Richard Huganir; Paul Greengard
cAMP-dependent protein kinase phosphorylates the nicotinic acetylcholine receptor.
Proceedings of the National Academy of Sciences of the United States of America 1983;80(4):1130-4.
1983: S I Walaas; Angus Nairn; Paul Greengard
Regional distribution of calcium- and cyclic adenosine 3':5'-monophosphate-regulated protein phosphorylation systems in mammalian brain. II. Soluble systems.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1983;3(2):302-11.
1983: S I Walaas; Angus Nairn; Paul Greengard
Regional distribution of calcium- and cyclic adenosine 3':5'-monophosphate-regulated protein phosphorylation systems in mammalian brain. I. Particulate systems.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1983;3(2):291-301.
1983: A C Dolphin; J A Detre; D J Schlichter; Angus Nairn; H H Yeh; D J Woodward; Paul Greengard
Cyclic nucleotide-dependent protein kinases and some major substrates in the rat cerebellum after neonatal X-irradiation.
Journal of neurochemistry 1983;40(2):577-81.
1983: S I Walaas; D W Aswad; Paul Greengard
A dopamine- and cyclic AMP-regulated phosphoprotein enriched in dopamine-innervated brain regions.
Nature 1983;301(5895):69-71.
1983: R M Lewis; W C Wallace; S D Kanazir; Paul Greengard
Expression of cell-type-specific neuronal phosphoproteins.
Cold Spring Harbor symposia on quantitative biology 1983;48 Pt 1():347-54.
1983: L J DeGennaro; S D Kanazir; W C Wallace; R M Lewis; Paul Greengard
Neuron-specific phosphoproteins as models for neuronal gene expression.
Cold Spring Harbor symposia on quantitative biology 1983;48 Pt 1():337-45.
1983: U Walter; Paul Greengard
Photoaffinity labeling of the regulatory subunit of cAMP-dependent protein kinase.
Methods in enzymology 1983;99():154-62.
1982: V F Castellucci; Angus Nairn; Paul Greengard; J H Schwartz; Eric R Kandel
Inhibitor of adenosine 3':5'-monophosphate-dependent protein kinase blocks presynaptic facilitation in Aplysia.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1982;2(12):1673-81.
1982: Angus Nairn; J A Detre; J E Casnellie; Paul Greengard
Serum antibodies that distinguish between the phospho- and dephospho-forms of a phosphoprotein.
Nature 1982;299(5885):734-6.
1982: K Tsou; Paul Greengard
Regulation of phosphorylation of proteins I, IIIa, and IIIb in rat neurohypophysis in vitro by electrical stimulation and by neuroactive agents.
Proceedings of the National Academy of Sciences of the United States of America 1982;79(19):6075-9.
1982: W C Wu; S I Walaas; Angus Nairn; Paul Greengard
Calcium/phospholipid regulates phosphorylation of a Mr "87k" substrate protein in brain synaptosomes.
Proceedings of the National Academy of Sciences of the United States of America 1982;79(17):5249-53.
1982: Eric J Nestler; Paul Greengard
Distribution of protein I and regulation of its state of phosphorylation in the rabbit superior cervical ganglion.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1982;2(8):1011-23.
1982: Eric J Nestler; M Zata; Paul Greengard
A diurnal rhythm in pineal protein 1 content mediated by beta-adrenergic neurotransmission.
Science (New York, N.Y.) 1982;217(4557):357-9.
1982: C K Huang; M D Browning; Paul Greengard
Purification and characterization of protein IIIb, a mammalian brain phosphoprotein.
The Journal of biological chemistry 1982;257(11):6524-8.
1982: H C Palfrey; W Schiebler; Paul Greengard
A major calmodulin-binding protein common to various vertebrate tissues.
Proceedings of the National Academy of Sciences of the United States of America 1982;79(12):3780-4.
1982: G Fried; Eric J Nestler; Pietro De Camilli; L Stjärne; L Olson; J M Lundberg; T Hökfelt; C C Ouimet; Paul Greengard
Cellular and subcellular localization of protein I in the peripheral nervous system.
Proceedings of the National Academy of Sciences of the United States of America 1982;79(8):2717-21.
1982: Eric J Nestler; Paul Greengard
Nerve impulses increase the phosphorylation state of protein I in rabbit superior cervical ganglion.
Nature 1982;296(5856):452-4.
1982: N L Robinson; P M Cox; Paul Greengard
Glutamate regulates adenylate cyclase and guanylate cyclase activities in an isolated membrane preparation from insect muscle.
Nature 1982;296(5855):354-6.
1981: W Sieghart; T C Theoharides; W W Douglas; Paul Greengard
Phosphorylation of a single mast cell protein in response to drugs that inhibit secretion.
Biochemical pharmacology 1981;30(19):2737-8.
1981: T C Theoharides; W Sieghart; Paul Greengard; W W Douglas
Somatostatin-induced phosphorylation of mast cell proteins.
Biochemical pharmacology 1981;30(19):2735-6.
1981: Eric J Nestler; T C Rainbow; B S McEwen; Paul Greengard
Corticosterone increases the amount of protein 1, a neuron-specific phosphoprotein, in rat hippocampus.
Science (New York, N.Y.) 1981;212(4499):1162-4.
1981: A C Dolphin; Paul Greengard
Presence of protein I, a phosphoprotein associated with synaptic vesicles, in cerebellar granule cells.
Journal of neurochemistry 1981;36(5):1627-31.
1981: A Aitken; T Bilham; P Cohen; D Aswad; Paul Greengard
A specific substrate from rabbit cerebellum for guanosine-3':5'-monophosphate-dependent protein kinase. III. Amino acid sequences at the two phosphorylation sites.
The Journal of biological chemistry 1981;256(7):3501-6.
1981: D W Aswad; Paul Greengard
A specific substrate from rabbit cerebellum for guanosine 3':5'-monophosphate-dependent protein kinase. II. Kinetic studies on its phosphorylation by guanosine 3':5'-monophosphate-dependent and adenosine 3':5'-monophosphate-dependent protein kinases.
The Journal of biological chemistry 1981;256(7):3494-500.
1981: D W Aswad; Paul Greengard
A specific substrate from rabbit cerebellum for guanosine 3':5'-monophosphate-dependent protein kinase. I. Purification and characterization.
The Journal of biological chemistry 1981;256(7):3487-93.
1981: S E Goelz; Eric J Nestler; B Chehrazi; Paul Greengard
Distribution of protein I in mammalian brain as determined by a detergent-based radioimmunoassay.
Proceedings of the National Academy of Sciences of the United States of America 1981;78(4):2130-4.
1981: A Y Liu; U Walter; Paul Greengard
Steroid hormones may regulate autophosphorylation of adenosine-3',5'-monophosphate-dependent protein kinase in target tissues.
European journal of biochemistry / FEBS 1981;114(3):539-48.
1981: W B Huttner; L J DeGennaro; Paul Greengard
Differential phosphorylation of multiple sites in purified protein I by cyclic AMP-dependent and calcium-dependent protein kinases.
The Journal of biological chemistry 1981;256(3):1482-8.
1981: M B Kennedy; Paul Greengard
Two calcium/calmodulin-dependent protein kinases, which are highly concentrated in brain, phosphorylate protein I at distinct sites.
Proceedings of the National Academy of Sciences of the United States of America 1981;78(2):1293-7.
1981: A C Dolphin; Paul Greengard
Neurotransmitter- and neuromodulator-dependent alterations in phosphorylation of protein I in slices of rat facial nucleus.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1981;1(2):192-203.
1981: S M Lohmann; U Walter; P E Miller; Paul Greengard; Pietro De Camilli
Immunohistochemical localization of cyclic GMP-dependent protein kinase in mammalian brain.
Proceedings of the National Academy of Sciences of the United States of America 1981;78(1):653-7.
1981: A C Dolphin; Paul Greengard
Serotonin stimulates phosphorylation of protein I in the facial motor nucleus of rat brain.
Nature 1981;289(5793):76-9.
1981: H C Palfrey; Paul Greengard
Hormone-sensitive ion transport systems in erythrocytes as models for epithelial ion pathways.
Annals of the New York Academy of Sciences 1981;372():291-308.
1981: U Walter; Paul Greengard
Cyclic AMP-dependent and cyclic GMP-dependent protein kinases of nervous tissue.
Current topics in cellular regulation 1981;19():219-56.
1980: Akio Yamazaki; I Sen; M W Bitensky; J E Casnellie; Paul Greengard
Cyclic GMP-specific, high affinity, noncatalytic binding sites on light-activated phosphodiesterase.
The Journal of biological chemistry 1980;255(23):11619-24.
1980: L K Kaczmarek; K R Jennings; F Strumwasser; Angus Nairn; U Walter; F D Wilson; Paul Greengard
Microinjection of catalytic subunit of cyclic AMP-dependent protein kinase enhances calcium action potentials of bag cell neurons in cell culture.
Proceedings of the National Academy of Sciences of the United States of America 1980;77(12):7487-91.
1980: H C Palfrey; S L Alper; Paul Greengard
Protein phosphorylation and the regulation of cation cotransport.
The Journal of experimental biology 1980;89():103-15.
1980: Eric J Nestler; Paul Greengard
Dopamine and depolarizing agents regulate the state of phosphorylation of protein I in the mammalian superior cervical sympathetic ganglion.
Proceedings of the National Academy of Sciences of the United States of America 1980;77(12):7479-83.
1980: V F Castellucci; Eric R Kandel; J H Schwartz; F D Wilson; Angus Nairn; Paul Greengard
Intracellular injection of t he catalytic subunit of cyclic AMP-dependent protein kinase simulates facilitation of transmitter release underlying behavioral sensitization in Aplysia.
Proceedings of the National Academy of Sciences of the United States of America 1980;77(12):7492-6.
1980: S L Alper; H C Palfrey; Susan A DeRiemer; Paul Greengard
Hormonal control of protein phosphorylation in turkey erythrocytes. Phosphorylation by cAMP-dependent and Ca2+-dependent protein kinases of distinct sites in goblin, a high molecular weight protein of the plasma membrane.
The Journal of biological chemistry 1980;255(22):11029-39.
1980: S M Lohmann; U Walter; Paul Greengard
Identification of endogenous substrate proteins for cAMP-dependent protein kinase in bovine brain.
The Journal of biological chemistry 1980;255(20):9985-92.
1980: S A Rudolph; Paul Greengard
Effects of catecholamines and prostaglandin E1 on cyclic AMP, cation fluxes, and protein phosphorylation in the frog erythrocyte.
The Journal of biological chemistry 1980;255(18):8534-40.
1980: D J Schlichter; J A Detre; D W Aswad; B Chehrazi; Paul Greengard
Localization of cyclic GMP-dependent protein kinase and substrate in mammalian cerebellum.
Proceedings of the National Academy of Sciences of the United States of America 1980;77(9):5537-41.
1980: S L Alper; K G Beam; Paul Greengard
Hormonal control of Na+-K+ co-transport in turkey erythrocytes. Multiple site phosphorylation of goblin, a high molecular weight protein of the plasma membrane.
The Journal of biological chemistry 1980;255(10):4864-71.
1980: H E Ives; J E Casnellie; Paul Greengard; J D Jamieson
Subcellular localization of cyclic GMP-dependent protein kinase and its substrates in vascular smooth muscle.
The Journal of biological chemistry 1980;255(8):3777-85.
1980: J E Casnellie; H E Ives; J D Jamieson; Paul Greengard
Cyclic GMP-dependent protein phosphorylation in intact medial tissue and isolated cells from vascular smooth muscle.
The Journal of biological chemistry 1980;255(8):3770-6.
1980: U Walter; P Miller; F Wilson; D Menkes; Paul Greengard
Immunological distinction between guanosine 3':5'-monophosphate-dependent and adenosine 3':5'-monophosphate-dependent protein kinases.
The Journal of biological chemistry 1980;255(8):3757-62.
1980: W Sieghart; H Schulman; Paul Greengard
Neuronal localization of Ca2+-dependent protein phosphorylation in brain.
Journal of neurochemistry 1980;34(3):548-53.
1980: H C Palfrey; P W Feit; Paul Greengard
cAMP-stimulated cation cotransport in avian erythrocytes: inhibition by "loop" diuretics.
The American journal of physiology 1980;238(3):C139-48.
1980: T C Theoharides; W Sieghart; Paul Greengard; W W Douglas
Antiallergic drug cromolyn may inhibit histamine secretion by regulating phosphorylation of a mast cell protein.
Science (New York, N.Y.) 1980;207(4426):80-2.
1980: H C Palfrey; Paul Greengard; P W Feit
Specific inhibition by "loop" diuretics of an anion-dependent Na+ + K+ cotransport system in avian erythrocytes.
Annals of the New York Academy of Sciences 1980;341():134-8.
1980: A C Dolphin; S E Goelz; Paul Greengard
Neuronal protein phosphorylation: recent studies concerning protein I, a synapse-specific phosphoprotein.
Pharmacology, biochemistry, and behavior 1980;13 Suppl 1():169-74.
1979: N R Krieger; B S Bunney; Paul Greengard
Localization of dopamine-sensitive adenylate cyclase activity within laminae of the rat prefrontal cortex.
Brain research 1979;179(1):171-5.
1979: U Walter; S M Lohmann; W Sieghart; Paul Greengard
Identification of the cyclic AMP-dependent protein kinase responsible for endogenous phosphorylation of substrate proteins in synaptic membrane fraction from rat brain.
The Journal of biological chemistry 1979;254(23):12235-9.
1979: F E Bloom; Tetsufumi Ueda; E Battenberg; Paul Greengard
Immunocytochemical localization, in synapses, of protein I, an endogenous substrate for protein kinases in mammalian brain.
Proceedings of the National Academy of Sciences of the United States of America 1979;76(11):5982-6.
1979: Pietro De Camilli; Tetsufumi Ueda; F E Bloom; E Battenberg; Paul Greengard
Widespread distribution of protein I in the central and peripheral nervous systems.
Proceedings of the National Academy of Sciences of the United States of America 1979;76(11):5977-81.
1979: Tetsufumi Ueda; Paul Greengard; K Berzins; R S Cohen; F Blomberg; Dennis Grab; P Siekevitz
Subcellular distribution in cerebral cortex of two proteins phosphorylated by a cAMP-dependent protein kinase.
The Journal of cell biology 1979;83(2 Pt 1):308-19.
1979: S A Rudolph; L R Hegstrand; Paul Greengard; S E Malawista
The interaction of colchicine with hormone-sensitive adenylate cyclase in human leukocytes.
Molecular pharmacology 1979;16(3):805-12.
1979: K G Beam; S L Alper; GE Palade; Paul Greengard
Hormonally regulated phosphoprotein of turkey erythrocytes: localization to plasma membrane.
The Journal of cell biology 1979;83(1):1-15.
1979: W B Huttner; Paul Greengard
Multiple phosphorylation sites in protein I and their differential regulation by cyclic AMP and calcium.
Proceedings of the National Academy of Sciences of the United States of America 1979;76(10):5402-6.
1979: U Strömbom; J Forn; A C Dolphin; Paul Greengard
Regulation of the state of phosphorylation of specific neuronal proteins in mouse brain by in vivo administration of anesthetic and convulsant agents.
Proceedings of the National Academy of Sciences of the United States of America 1979;76(9):4687-90.
1979: U Walter; M R Costa; X O Breakefield; Paul Greengard
Presence of free cyclic AMP receptor protein and regulation of its level by cyclic AMP in neuroblastoma-glioma hybrid cells.
Proceedings of the National Academy of Sciences of the United States of America 1979;76(7):3251-5.
1979: Paul Greengard
Cyclic nucleotides, phosphorylated proteins, and the nervous system.
Federation proceedings 1979;38(8):2208-17.
1979: W Sieghart; J Forn; Paul Greengard
Ca2+ and cyclic AMP regulate phosphorylation of same two membrane-associated proteins specific to nerve tissue.
Proceedings of the National Academy of Sciences of the United States of America 1979;76(5):2475-9.
1979: P D Kanof; Paul Greengard
Pharmacological properties of histamine-sensitive adenylate cyclase from guinea pig cardiac ventricular muscle.
Molecular pharmacology 1979;15(3):445-61.
1979: P D Kanof; Paul Greengard
Pharmacological properties of histamine-sensitive adenylate cyclase from mammalian brain.
The Journal of pharmacology and experimental therapeutics 1979;209(1):87-96.
1979: W Sieghart; U Strombom; U Walter; Paul Greengard
Drug interactions with cyclic nucleotide and protein phosphorylation systems.
Progress in clinical and biological research 1979;27():123-34.
1979: Paul Greengard
Intracellular signals in the brain.
Harvey lectures 1979;75():277-331.
1978: S M Lohmann; U Walter; Paul Greengard
Protein kinases in developing rat brain.
Journal of cyclic nucleotide research 1978;4(6):445-52.
1978: U Walter; Paul Greengard
Quantitative labeling of the regulatory subunit of type II cAMP-dependent protein kinase from bovine heart by a photoaffinity analog.
Journal of cyclic nucleotide research 1978;4(6):437-44.
1978: R E Study; X O Breakefield; T Bartfai; Paul Greengard
Voltage-sensitive calcium channels regulate guanosine 3',5'-cyclic monophosphate levels in neuroblastoma cells.
Proceedings of the National Academy of Sciences of the United States of America 1978;75(12):6295-9.
1978: R E Study; Paul Greengard
Regulation by histamine of cyclic nucleotide levels in sympathetic ganglia.
The Journal of pharmacology and experimental therapeutics 1978;207(3):767-78.
1978: W Sieghart; J Forn; Robert Schwarcz; J T Coyle; Paul Greengard
Neuronal localization of specific brain phosphoproteins.
Brain research 1978;156(2):345-50.
1978: H Schulman; Paul Greengard
Ca2+-dependent protein phosphorylation system in membranes from various tissues, and its activation by "calcium-dependent regulator".
Proceedings of the National Academy of Sciences of the United States of America 1978;75(11):5432-6.
1978: T Bartfai; X O Breakefield; Paul Greengard
Regulation of synthesis of guanosine 3':5'-cyclic monophosphate in neuroblastoma cells.
The Biochemical journal 1978;176(1):119-27.
1978: Eric J Nestler; K G Beam; Paul Greengard
Nicotinic cholinergic stimulation increases cyclic GMP levels in vertebrate skeletal muscle.
Nature 1978;275(5679):451-3.
1978: J Forn; Paul Greengard
Depolarizing agents and cyclic nucleotides regulate the phosphorylation of specific neuronal proteins in rat cerebral cortex slices.
Proceedings of the National Academy of Sciences of the United States of America 1978;75(10):5195-9.
1978: W Sieghart; T C Theoharides; S L Alper; W W Douglas; Paul Greengard
Calcium-dependent protein phosphorylation during secretion by exocytosis in the mast cell.
Nature 1978;275(5678):329-31.
1978: U Walter; P Kanof; H Schulman; Paul Greengard
Adenosine 3':5'-monophosphate receptor proteins in mammalian brain.
The Journal of biological chemistry 1978;253(17):6275-80.
1978: S M Lohmann; Tetsufumi Ueda; Paul Greengard
Ontogeny of synaptic phosphoproteins in brain.
Proceedings of the National Academy of Sciences of the United States of America 1978;75(8):4037-41.
1978: J E Casnellie; D J Schlichter; U Walter; Paul Greengard
Photoaffinity labeling of a guanosine 3':5'-monophosphate-dependent protein kinase from vascular smooth muscle.
The Journal of biological chemistry 1978;253(13):4771-6.
1978: D J Schlichter; J E Casnellie; Paul Greengard
An endogenous substrate for cGMP-dependent protein kinase in mammalian cerebellum.
Nature 1978;273(5657):61-2.
1978: P D Kanof; Paul Greengard
Brain histamine receptors as targets for antidepressant drugs.
Nature 1978;272(5651):329-33.
1978: H Schulman; Paul Greengard
Stimulation of brain membrane protein phosphorylation by calcium and an endogenous heat-stable protein.
Nature 1978;271(5644):478-9.
1978: Paul Greengard
Phosphorylated proteins as physiological effectors.
Science (New York, N.Y.) 1978;199(4325):146-52.
1977: S A Rudolph; D E Schafer; Paul Greengard
Effects of cholera enterotoxin on catecholamine-stimulated changes in cation fluxes, cell volume, and cyclic AMP levels in the turkey erythrocyte.
The Journal of biological chemistry 1977;252(20):7132-9.
1977: U Walter; I Uno; A Y Liu; Paul Greengard
Study of autophosphorylation of isoenzymes of cyclic AMP-dependent protein kinases.
The Journal of biological chemistry 1977;252(19):6588-90.
1977: I Uno; Tetsufumi Ueda; Paul Greengard
Enzyme systems involved in phosphorylation and dephosphorylation of two endogenous phosphoproteins in neuronal membranes.
Archives of biochemistry and biophysics 1977;183(2):480-9.
1977: U Walter; I Uno; A Y Liu; Paul Greengard
Identification, characterization, and quantitative measurement of cyclic AMP receptor proteins in cytosol of various tissues using a photoaffinity ligand.
The Journal of biological chemistry 1977;252(18):6494-500.
1977: N R Krieger; J S Kauer; G M Shepherd; Paul Greengard
Dopamine-sensitive adenylate cyclase within laminae of the olfactory tubercle.
Brain research 1977;131(2):303-12.
1977: S A Rudolph; Paul Greengard; S E Malawista
Effects of colchicine on cyclic AMP levels in human leukocytes.
Proceedings of the National Academy of Sciences of the United States of America 1977;74(8):3404-8.
1977: J A Nathanson; Paul Greengard
"Second messengers" in the brain.
Scientific American 1977;237(2):109-19.
1977: Tetsufumi Ueda; Paul Greengard
Adenosine 3':5'-monophosphate-regulated phosphoprotein system of neuronal membranes. I. Solubilization, purification, and some properties of an endogenous phosphoprotein.
The Journal of biological chemistry 1977;252(14):5155-63.
1977: I Uno; Tetsufumi Ueda; Paul Greengard
Adenosine 3':5'-monophosphate-regulated phosphoprotein system of neuronal membranes. II. Solubilization, purification, and some properties of an endogenous adenosine 3':5'-monophosphate-dependent protein kinase.
The Journal of biological chemistry 1977;252(14):5164-74.
1977: P D Kanof; L R Hegstrand; Paul Greengard
Biochemical characterization of histamine-sensitive adenylate cyclase in mammalian brain.
Archives of biochemistry and biophysics 1977;182(1):321-34.
1977: K G Beam; Eric J Nestler; Paul Greengard
Increased cyclic GMP levels associated with contraction in muscle fibres of the giant barnacle.
Nature 1977;267(5611):534-6.
1977: Bruce K Krueger; J Forn; Paul Greengard
Depolarization-induced phosphorylation of specific proteins, mediated by calcium ion influx, in rat brain synaptosomes.
The Journal of biological chemistry 1977;252(8):2764-73.
1976: J Forn; Paul Greengard
Regulation by lipolytic and antillipolytic compounds of the phosphorylation of specific proteins in isolated intact fat cells.
Archives of biochemistry and biophysics 1976;176(2):721-33.
1976: Bruce K Krueger; J Forn; J R Walters; Robert H Roth; Paul Greengard
Stimulation by dopamine of adenosine cyclic 3',5'-monophosphate formation in rat caudate nucleus: effect of lesions of the nigro-neostriatal pathway.
Molecular pharmacology 1976;12(4):639-48.
1976: Paul Greengard
Possible role for cyclic nucleotides and phosphorylated membrane proteins in postsynaptic actions of neurotransmitters.
Nature 1976;260(5547):101-8.
1976: L R Hegstrand; P D Kanof; Paul Greengard
Histamine-sensitive adenylate cyclase in mammalian brain.
Nature 1976;260(5547):163-5.
1976: A Y Liu; Paul Greengard
Regulation by steroid hormones of phosphorylation of specific protein common to several target organs.
Proceedings of the National Academy of Sciences of the United States of America 1976;73(2):568-72.
1976: K G Beam; Paul Greengard
Cyclic nucleotides, protein phosphorylation and synaptic function.
Cold Spring Harbor symposia on quantitative biology 1976;40():157-68.
1975: J W Kebabian; F E Blood; A L Steiner; Paul Greengard
Neurotransmitters increase cyclic nucleotides in postganglionic neurons: immunocytochemical demonstration.
Science (New York, N.Y.) 1975;190(4210):157-9.
1975: Bruce K Krueger; J Forn; Paul Greengard
Dopamine-sensitive adenylate cyclase and protein phosphorylation in the rat caudate nucleus.
Psychopharmacology bulletin 1975;11(4):10-1.
1975: Tetsufumi Ueda; S A Rudolph; Paul Greengard
Solubilization of a phosphoprotein and its associated cyclic AMP-dependent protein kinase and phosphoprotein phosphatase from synaptic membrane fractions, and some kinetic evidence for their existence as a complex.
Archives of biochemistry and biophysics 1975;170(2):492-503.
1975: A H Pomerantz; S A Rudolph; B E Haley; Paul Greengard
Photoaffinity labeling of a protein kinase from bovine brain with 8-azidoadenosine 3',5'-monophosphate.
Biochemistry 1975;14(17):3858-62.
1975: Y C Clement-Cormier; R G Parrish; G L Petzold; J W Kerabian; Paul Greengard
Characterization of a dopamine-sensitive adenylate cyclase in the rat caudate nucleus.
Journal of neurochemistry 1975;25(2):143-9.
1975: J W Kebabian; A L Steiner; Paul Greengard
Muscarinic cholinergic regulation of cyclic guanosine 3,5-monophosphate in autonomic ganglia: possible role in synaptic transmission.
The Journal of pharmacology and experimental therapeutics 1975;193(2):474-88.
1975: Paul Greengard
Antipsychotic drugs: roles of cyclic AMP.
Psychopharmacology bulletin 1975;11(2):45.
1975: V H Morgenroth; L R Hegstrand; Robert H Roth; Paul Greengard
Evidence for involvement of protein kinase in the activation by adenosine 3':5'-monophosphate of brain tyrosine 3-monooxygenase.
The Journal of biological chemistry 1975;250(5):1946-8.
1975: A M Malkinson; Bruce K Krueger; S A Rudolph; J E Casnellie; B E Haley; Paul Greengard
Widespread occurrence of a specific protein in vertebrate tissues and regulation by cyclic AMP of its endogenous phosphorylation and dephosphorylation.
Metabolism: clinical and experimental 1975;24(3):331-41.
1975: K G Walton; R J DeLorenzo; P F Curran; Paul Greengard
Regulation of protein phosphorylation and sodium transport in toad bladder.
The Journal of general physiology 1975;65(2):153-77.
1975: J W Kebabian; Y C Clement-Cormier; G L Petzold; Paul Greengard
Chemistry of dopamine receptors.
Advances in neurology 1975;9():1-11.
1975: Paul Greengard
Cyclic nucleotides, protein phosphorylation, and neuronal function.
Advances in cyclic nucleotide research 1975;5():585-601.
1975: R D Sloboda; S A Rudolph; J L Rosenbaum; Paul Greengard
Cyclic AMP-dependent endogenous phosphorylation of a microtubule-associated protein.
Proceedings of the National Academy of Sciences of the United States of America 1975;72(1):177-81.
1974: J Forn; Bruce K Krueger; Paul Greengard
Adenosine 3',5'-monophosphate content in rat caudate nucleus: demonstration of dopaminergic and adrenergic receptors.
Science (New York, N.Y.) 1974;186(4169):1118-20.
1974: F F Weight; G Petzold; Paul Greengard
Guanosine 3',5'-monophosphate in sympathetic ganglia: increase assoicated with synaptic transmission.
Science (New York, N.Y.) 1974;186(4167):942-4.
1974: H Maeno; P L Reyes; Tetsufumi Ueda; S A Rudolph; Paul Greengard
Autophosphorylation of adenosine 3',5'-monophosphate-dependent protein kinase from bovine brain.
Archives of biochemistry and biophysics 1974;164(2):551-9.
1974: A Y Liu; Paul Greengard
Aldosterone-induced increase in protein phosphatase activity of toad bladder.
Proceedings of the National Academy of Sciences of the United States of America 1974;71(10):3869-73.
1974: S A Rudolph; Paul Greengard
Regulation of protein phosphorylation and membrane permeability by beta-adrenergic agents and cyclic adenosine 3':5'-monophosphate in the avian erythrocyte.
The Journal of biological chemistry 1974;249(17):5684-7.
1974: J E Casnellie; Paul Greengard
Guanosine 3':5'-cyclic monophosphate-dependent phosphorylation of endogenous substrate proteins in membranes of mammalian smooth muscle.
Proceedings of the National Academy of Sciences of the United States of America 1974;71(5):1891-5.
1974: Paul Greengard; J W Kebabian
Role of cyclic AMP in synaptic transmission in the mammalian peripheral nervous system.
Federation proceedings 1974;33(4):1059-67.
1974: Y C Clement-Cormier; J W Kebabian; G L Petzold; Paul Greengard
Dopamine-sensitive adenylate cyclase in mammalian brain: a possible site of action of antipsychotic drugs.
Proceedings of the National Academy of Sciences of the United States of America 1974;71(4):1113-7.
1974: J A Nathanson; Paul Greengard
Serotonin-sensitive adenylate cyclase in neural tissue and its similarity to the serotonin receptor: a possible site of action of lysergic acid diethylamide.
Proceedings of the National Academy of Sciences of the United States of America 1974;71(3):797-801.
1974: P Kalix; D A McAfee; M Schorderet; Paul Greengard
Pharmacological analysis of synaptically mediated increase in cyclic adenosine monophosphate in rabbit superior cervical ganglion.
The Journal of pharmacology and experimental therapeutics 1974;188(3):676-87.
1974: J F Kuo; Paul Greengard
Assay of cyclic GMP by activation of cyclic GMP-dependent protein kinase.
Methods in enzymology 1974;38():90-5.
1974: J F Kuo; Paul Greengard
Purification and characterization of cyclic GMP-dependent protein kinases.
Methods in enzymology 1974;38():329-50.
1974: Paul Greengard
Biochemical characterization of the dopamine receptor in the mammalian caudate nucleus.
Journal of psychiatric research 1974;11():87-90.
1973: Tetsufumi Ueda; H Maeno; Paul Greengard
Regulation of endogenous phosphorylation of specific proteins in synaptic membrane fractions from rat brain by adenosine 3':5'-monophosphate.
The Journal of biological chemistry 1973;248(23):8295-305.
1973: R J Delorenzo; Paul Greengard
Activation by adenosine 3':5'-monophosphate of a membrane-bound phosphoprotein phosphatase from toad bladder.
Proceedings of the National Academy of Sciences of the United States of America 1973;70(6):1831-5.
1973: J A Nathanson; Paul Greengard
Octopamine-sensitive adenylate cyclse: evidence for a biological role of octopamine in nervous tissue.
Science (New York, N.Y.) 1973;180(4083):308-10.
1973: R J DeLorenzo; K G Walton; P F Curran; Paul Greengard
Regulation of phosphorylation of a specific protein in toad-bladder membrane by antidiuretic hormone and cyclic AMP, and its possible relationship to membrane permeability changes.
Proceedings of the National Academy of Sciences of the United States of America 1973;70(3):880-4.
1973: T E Donnelly; J F Kuo; E Miyamoto; Paul Greengard
Protein kinase modulator from lobster tail muscle. II. Effects of the modulator on holoenzyme and catalytic subunit of guanosine 3',5'-monophosphate-dependent and adenosine 3',5'-monophosphate-dependent protein kinases.
The Journal of biological chemistry 1973;248(1):199-203.
1973: T E Donnelly; J F Kuo; P L Reyes; Y P Liu; Paul Greengard
Protein kinase modulator from lobster tail muscle. I. Stimulatory and inhibitory effects of the modulator on the phosphorylation of substrate proteins by guanosine 3',5'-monophosphate-dependent and adenosine 3',5'-monophosphate-dependent protein kinases.
The Journal of biological chemistry 1973;248(1):190-8.
1973: E Miyamoto; G L Petzold; J F Kuo; Paul Greengard
Dissociation and activation of adenosine 3',5'-monophosphate-dependent and guanosine 3',5'-monophosphate-dependent protein kinases by cyclic nucleotides and by substrate proteins.
The Journal of biological chemistry 1973;248(1):179-89.
1972: Richard W Tsien; W Giles; Paul Greengard
Cyclic AMP mediates the effects of adrenaline on cardiac purkinje fibres.
Nature: New biology 1972;240(101):181-3.
1972: T P Lee; J F Kuo; Paul Greengard
Role of muscarinic cholinergic receptors in regulation of guanosine 3':5'-cyclic monophosphate content in mammalian brain, heart muscle, and intestinal smooth muscle.
Proceedings of the National Academy of Sciences of the United States of America 1972;69(11):3287-91.
1972: D A McAfee; Paul Greengard
Adenosine 3',5'-monophosphate: electrophysiological evidence for a role in synaptic transmission.
Science (New York, N.Y.) 1972;178(58):310-2.
1972: E M Johnson; Tetsufumi Ueda; H Maeno; Paul Greengard
Adenosine 3',5-monophosphate-dependent phosphorylation of a specific protein in synaptic membrane fractions from rat cerebrum.
The Journal of biological chemistry 1972;247(17):5650-2.
1972: J W Kebabian; G L Petzold; Paul Greengard
Dopamine-sensitive adenylate cyclase in caudate nucleus of rat brain, and its similarity to the "dopamine receptor".
Proceedings of the National Academy of Sciences of the United States of America 1972;69(8):2145-9.
1972: Paul Greengard
Adenosine 3':5'-cyclic monophosphate as a mediator in the action of neurohumoral agents.
The Biochemical journal 1972;128(3):75P-77P.
1972: H Maeno; Paul Greengard
Phosphoprotein phosphatases from rat cerebral cortex. Subcellular distribution and characterization.
The Journal of biological chemistry 1972;247(10):3269-77.
1972: J F Kuo; T P Lee; P L Reyes; K G Walton; T E Donnelly; Paul Greengard
Cyclic nucleotide-dependent protein kinases. X. An assay method for the measurement of quanosine 3',5'-monophosphate in various biological materials and a study of agents regulating its levels in heart and brain.
The Journal of biological chemistry 1972;247(1):16-22.
1972: Paul Greengard; D A McAfee
Adenosine 3':5'-cyclic monophosphate as a mediator in the action of neurohumoral agents.
Biochemical Society symposium 1972;(36):87-102.
1972: Paul Greengard; D A McAfee; J W Kebabian
On the mechanism of action of cyclic AMP and its role in synaptic transmission.
Advances in cyclic nucleotide research 1972;1():337-55.
1972: J F Kuo; Paul Greengard
An assay method for cyclic AMP and cyclic GMP based upon their abilities to activate cyclic AMP-dependent and cyclic GMP-dependent protein kinases.
Advances in cyclic nucleotide research 1972;2():41-50.
1972: J W Kebabian; J F Kuo; Paul Greengard
Determination of relative levels of cyclic AMP in tissues or cells prelabeled with radioactive adenine.
Advances in cyclic nucleotide research 1972;2():131-7.
1971: Paul Greengard
On the reactivity and mechanism of action of cyclic nucleotides.
Annals of the New York Academy of Sciences 1971;185():18-26.
1971: E M Johnson; H Maeno; Paul Greengard
Phosphorylation of endogenous protein of rat brain by cyclic adenosine 3',5'-monophosphate-dependent protein kinase.
The Journal of biological chemistry 1971;246(24):7731-9.
1971: J W Kebabian; Paul Greengard
Dopamine-sensitive adenyl cyclase: possible role in synaptic transmission.
Science (New York, N.Y.) 1971;174(4016):1346-9.
1971: J F Kuo; G R Wyatt; Paul Greengard
Cyclic nucleotide-dependent protein kinases. IX. Partial purification and some properties of guanosine 3',5'-monophosphate-dependent and adenosine 3',5'-monophosphate-dependent protein kinases from various tissues and species of Arthropoda.
The Journal of biological chemistry 1971;246(23):7159-67.
1971: T P Lee; J F Kuo; Paul Greengard
Regulation of myocardial cyclic AMP by isoproterenol, glucagon and acetylcholine.
Biochemical and biophysical research communications 1971;45(4):991-7.
1971: O Hayaishi; Paul Greengard; S P Colowick
On the equilibrium of the adenylate cyclase reaction.
The Journal of biological chemistry 1971;246(18):5840-3.
1971: G Lukas; S D Brindle; Paul Greengard
The route of absorption of intraperitoneally administered compounds.
The Journal of pharmacology and experimental therapeutics 1971;178(3):562-4.
1971: N T Florendo; R J Barrnett; Paul Greengard
Cyclic 3',5'-nucleotide phosphodiesterase: cytochemical localization in cerebral cortex.
Science (New York, N.Y.) 1971;173(3998):745-7.
1971: E Miyamoto; G L Petzold; J S Harris; Paul Greengard
Dissociation and concomitant activation of adenosine 3',5'-monophosphate-dependent protein kinase by histone.
Biochemical and biophysical research communications 1971;44(2):305-12.
1971: D A McAfee; M Schorderet; Paul Greengard
Adenosine 3',5'-monophosphate in nervous tissue: increase associated with synaptic transmission.
Science (New York, N.Y.) 1971;171(3976):1156-8.
1971: S A Rudolph; E M Johnson; Paul Greengard
The enthalpy of hydrolysis of various 3',5'-and 2',3'-cyclic nucleotides.
The Journal of biological chemistry 1971;246(5):1271-3.
1971: V P Whittaker; Paul Greengard
The isolation of synaptosomes from the brain of a teleost fish, Centriopristes striatus.
Journal of neurochemistry 1971;18(2):173-6.
1971: H Maeno; E M Johnson; Paul Greengard
Subcellular distribution of adenosine 3',5'-monophosphate-dependent protein kinase in rat brain.
The Journal of biological chemistry 1971;246(1):134-42.
1970: J F Kuo; Paul Greengard
Cyclic nucleotide-dependent protein kinases. VII. Comparison of various histones as substrates for adenosine 3',5'-monophosphate-dependent and guanosine 3',5'-monophosphate-dependent protein kinases.
Biochimica et biophysica acta 1970;212(3):434-40.
1970: J F Kuo; Paul Greengard
Stimulation of adenosine 3',5'-monophosphate-dependent and guanosine 3',5'-monophosphate-dependent protein kinases by some analogs of adenosine 3',5'-monophosphate.
Biochemical and biophysical research communications 1970;40(5):1032-8.
1970: J F Kuo; Paul Greengard
Cyclic nucleotide-dependent protein kinases. 8. An assay method for the measurement of adenosine 3',5'-monophosphate in various tissues and a study of agents influencing its level in adipose cells.
The Journal of biological chemistry 1970;245(16):4067-73.
1970: J F Kuo; Bruce K Krueger; Joshua R Sanes; Paul Greengard
Cyclic nucleotide-dependent protein kinases. V. Preparation and properties of adenosine 3',5'-monophosphate-dependent protein kinase from various bovine tissues.
Biochimica et biophysica acta 1970;212(1):79-91.
1970: J F Kuo; Paul Greengard
Cyclic nucleotide-dependent protein kinases. VI. Isolation and partial purification of a protein kinase activated by guanosine 3',5'-monophosphate.
The Journal of biological chemistry 1970;245(10):2493-8.
1970: L Reik; G L Petzold; J A Higgins; Paul Greengard; R J Barrnett
Hormone-sensitive adenyl cyclase: cytochemical localization in rat liver.
Science (New York, N.Y.) 1970;168(3929):382-4.
1970: Paul Greengard; J F Kuo
On the mechanism of action of cyclic AMP.
Advances in biochemical psychopharmacology 1970;3():287-306.
1970: Paul Greengard; J F Kuo; E Miyamoto
Studies on the mechanism of action of cyclic AMP in nervous and other tissues.
Advances in enzyme regulation 1970;9():113-25.
1969: E Miyamoto; J F Kuo; Paul Greengard
Cyclic nucleotide-dependent protein kinases. 3. Purification and properties of adenosine 3',5'-monophosphate-dependent protein kinase from bovine brain.
The Journal of biological chemistry 1969;244(23):6395-402.
1969: J F Kuo; Paul Greengard
Cyclic nucleotide-dependent protein kinases. IV. Widespread occurrence of adenosine 3',5'-monophosphate-dependent protein kinase in various tissues and phyla of the animal kingdom.
Proceedings of the National Academy of Sciences of the United States of America 1969;64(4):1349-55.
1969: A den Hertog; Paul Greengard; J M Ritchie
On the metabolic basis of nervous activity.
The Journal of physiology 1969;204(3):511-21.
1969: Paul Greengard; S A Rudolph; Julian M Sturtevant
Enthalpy of hydrolysis of the 3' bond of adenosine 3',5'-monophosphate and guanosine 3',5'-monophosphate.
The Journal of biological chemistry 1969;244(17):4798-800.
1969: E Miyamoto; J F Kuo; Paul Greengard
Adenosine 3',5'-monophosphate-dependent protein kinase from brain.
Science (New York, N.Y.) 1969;165(3888):63-5.
1969: J F Kuo; Paul Greengard
An adenosine 3',5'-monophosphate-dependent protein kinase from Escherichia coli.
The Journal of biological chemistry 1969;244(12):3417-9.
1969: Paul Greengard; B Petrack; H J Kalinsky
Identification of hormonally controlled endogenous inhibitor of livernicotinamide deamidase.
Biochimica et biophysica acta 1969;184(1):148-53.
1968: Paul Greengard; H Kalinsky; T J Manning; S B Zak
Prevention and remission by adrenocortical steriods of nicotinamide deficiency disease. II. A study of the mechanism.
The Journal of biological chemistry 1968;243(16):4216-21.
1968: E Miyamoto; J F Kuo; Paul Greengard
Adenosine 3',5'-monophosphate-dependent protein kinase from brain.
Science (New York, N.Y.) 1968;165(3888):63-5.
1968: Paul Greengard; H J Kalinsky; T J Manning
Tryptophan pyrrolase activity during pregnancy.
Biochimica et biophysica acta 1968;156(1):198-9.
1967: Paul Greengard; S Psychoyos; H H Tallan; D Y Cooper; O Rosenthal; R W Estabrook
Aldosterone synthesis by adrenal mitochondria. 3. Participation of cytochrome P-450.
Archives of biochemistry and biophysics 1967;121(2):298-303.
1967: G P Quinn; M M Cohn; M B Reid; Paul Greengard; M Weiner
The effect of formulation on phenmetrazine plasma levels in man studied by a sensitive analytic method.
Clinical pharmacology and therapeutics 1967;8(3):369-73.
1967: B N Berg; E B Sigg; Paul Greengard
Maintenance of pregnancy in protein-deficient rats by adrenocortical steroid or ACTH administration.
Endocrinology 1967;80(5):829-34.
1967: H H Tallan; S Psychoyos; Paul Greengard
Aldosterone synthesis by adrenal mitochondria. II. The effect of citric acid cycle intermediates; identification of the soluble stimulatory factor as fumarase.
The Journal of biological chemistry 1967;242(8):1912-4.
1967: S Gluecksohn-Waelsch; Paul Greengard; G P Quinn; L S Teicher
Genetic variations of an oxidase in mammals.
The Journal of biological chemistry 1967;242(6):1271-3.
1967: Paul Greengard; B Petrack; H Kalinsky
Effect of hypophysectomy on pyridine nucleotide metabolism. The role of nicotinamide.
The Journal of biological chemistry 1967;242(1):152-4.
1966: Paul Greengard; E B Sigg; I Fratta; S B Zak
Prevention and remission by adrenocortical steroids of nicotinamide deficiency disorders and of 6-aminonicotinamide toxicity in rats and dogs.
The Journal of pharmacology and experimental therapeutics 1966;154(3):624-31.
1966: G P Quinn; Paul Greengard; M B Reid
Prevention by antidepressant drugs of reserpine effect on pyridine nucleotide metabolism.
Molecular pharmacology 1966;2(4):347-51.
1966: G P Quinn; Paul Greengard
The pathway for the biosynthesis of N 1-methyl-4-pyridone-3-carboxamide.
Archives of biochemistry and biophysics 1966;115(1):146-52.
1966: S Psychoyos; H H Tallan; Paul Greengard
Aldosterone synthesis by adrenal mitochondria.
The Journal of biological chemistry 1966;241(12):2949-56.
1966: B Petrack; Paul Greengard; H Kalinsky
On the relative efficacy of nicotinamide and nicotinic acid as precursors of nicotinamide adenine dinucleotide.
The Journal of biological chemistry 1966;241(10):2367-72.
1966: F Märki; Paul Greengard
Nicotinamide deamidase in Ehrlich ascites tumor cells.
Biochimica et biophysica acta 1966;113(3):587-94.
1966: J M Ritchie; Paul Greengard
On the mode of action of local anesthetics.
Annual review of pharmacology 1966;6():405-30.
1965: J M Ritchie; B Ritchie; Paul Greengard
The effect of the nerve sheath on the action of local anesthetics.
The Journal of pharmacology and experimental therapeutics 1965;150(1):160-4.
1965: J M Ritchie; B Ritchie; Paul Greengard
The active structure of local anesthetics.
The Journal of pharmacology and experimental therapeutics 1965;150(1):152-9.
1965: B PETRACK; Paul Greengard; A CRASTON; F SHEPPY
NICOTINAMIDE DEAMIDASE FROM MAMMALIAN LIVER.
The Journal of biological chemistry 1965;240():1725-30.
1965: Paul Greengard; G P QUINN; M B REID
IDENTIFICATION OF HORMONES AFFECTING PYRIDINE NUCLEOTIDE METABOLISM OF RAT LIVER.
The Journal of biological chemistry 1965;240():486-90.
1964: I FRATTA; S B ZAK; Paul Greengard; E B SIGG
FETAL DEATH FROM NICOTINAMIDE-DEFICIENT DIET AND ITS PREVENTION BY CHLORPROMAZINE AND IMIPRAMINE.
Science (New York, N.Y.) 1964;145(3639):1429-30.
1964: Paul Greengard; G P QUINN; M B REID
PITUITARY INFLUENCE OF PYRIDINE NUCLEOTIDE METABOLISM OF RAT LIVER.
The Journal of biological chemistry 1964;239():1887-92.
1963: S B ZAK; H H TALLAN; G P QUINN; I FRATTA; Paul Greengard
THE DETERMINATION AND PHYSIOLOGICAL DISTRIBUTION OF DIPYRIDAMOLE AND ITS GLUCURONIDES IN BIOLOGICAL MATERIAL.
The Journal of pharmacology and experimental therapeutics 1963;141():392-8.
1962: Paul Greengard; R W STRAUB
Metabolic studies on the hyperpolarization following activity in mammalian non-myelinated nerve fibres.
The Journal of physiology 1962;161():414-23.
1962: Paul Greengard; G P QUINN
Metabolic effects of tranquilizers and hypophysectomy.
Annals of the New York Academy of Sciences 1962;96():179-84.
1961: Paul Greengard; Y H KALINSK; B PETRACK
Effect of hypophysectomy on liver diphosphopyridine nucleotide: the role of nicotinamide.
Biochimica et biophysica acta 1961;52():408-9.
1961: J M RITCHIE; Paul Greengard
On the active structure of local anesthetics.
The Journal of pharmacology and experimental therapeutics 1961;133():241-5.
1961: Paul Greengard; G P QUINN; M A LANDRAU
Hormonal effects on DPN concentration in rat liver.
Biochimica et biophysica acta 1961;47():614-6.
1960: M A CHIRIGOS; Paul Greengard; S UDENFRIEND
Uptake of tyrosine by rat brain in vivo.
The Journal of biological chemistry 1960;235():2075-9.
1959: Paul Greengard; K MINNAERT; E C SLATER; I BETEL
Yield of oxidative phosphorylation associated with the oxidation of succinate to fumarate.
The Biochemical journal 1959;73():637-46.
1959: Paul Greengard; R W STRAUB
Effect of frequency of electrical stimulation on the concentration of intermediary metabolites in mammalian non-myelinated fibres.
The Journal of physiology 1959;148():353-61.
1959: Paul Greengard; R W STRAUB
Restoration by barium of action potentials in sodium-deprived mammalian B and C fibres.
The Journal of physiology 1959;145(3):562-9.
1958: Paul Greengard; R W STRAUB
After-potentials in mammalian non-myelinated nerve fibres.
The Journal of physiology 1958;144(3):442-62.
1958: Paul Greengard; R W STRAUB
Effect of electrical stimulation on the concentration of phosphorylated intermediary metabolites in mammalian non-myelinated fibres.
The Journal of physiology 1958;140(1):18-9P.
1956: Paul Greengard
Determination of intermediary metabolites by enzymic fluorimetry.
Nature 1956;178(4534):632-4.
1954: Paul Greengard; F BRINK; S P COLOWICK
Some relationships between action potential, oxygen consumption and coenzyme content in degenerating peripheral axons.
Journal of cellular physiology 1954;44(3):395-420.