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Johann Greil

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R Beier; Arndt Borkhardt; U Creutzig; Karoline Ehlert; Matthias Eyrich; Johann Greil; Bernd Gruhn; Rupert Handgretinger; W Holter; Thomas Klingebiel; Bernhard Kremens; Peter Lang; C Mauz-Körholz; R Meisel; I Müller; Christina Peters; Dirk Reinhardt; André Schrauder; Ansgar Schulz; F R Schuster; Petr Sedlacek; Brigitte Strahm; Karl-Walter Sykora; Wilhelm Wössmann; Martin Zimmermann; Michael H Albert; Peter Bader; M G Sauer
Allo-SCT using BU, CY and melphalan for children with AML in second CR.
R Beier; Karoline Ehlert; Matthias Eyrich; Johann Greil; Bernd Gruhn; W Holter; Manfred Hönig; R Meisel; I Müller; W Nürnberger; M Sauer; Paul G Schlegel; Ansgar Schulz; K D Stachel; Meinolf Suttorp; Christian Urban; Wilhelm Wössmann; Martin Zimmermann; Peter Bader; Karl-Walter Sykora
Long-term follow-up of children conditioned with Treosulfan: German and Austrian experience.
Vanya Icheva; Simone Kayser; Christina Kyzirakos; Peter Lang; Michaela Nathrath; Michael Schumm; Wolfgang Schwinger; Stefan Stevanovic; Sebastian Tuve; Daniel Wolff; Michael H Albert; Wolfgang A Bethge; Johann Greil; Rupert Handgretinger; Tobias Feuchtinger
Adoptive transfer of epstein-barr virus (EBV) nuclear antigen 1-specific t cells as treatment for EBV reactivation and lymphoproliferative disorders after allogeneic stem-cell transplantation.

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All Publications

2013: R Beier; Arndt Borkhardt; U Creutzig; Karoline Ehlert; Matthias Eyrich; Johann Greil; Bernd Gruhn; Rupert Handgretinger; W Holter; Thomas Klingebiel; Bernhard Kremens; Peter Lang; C Mauz-Körholz; R Meisel; I Müller; Christina Peters; Dirk Reinhardt; André Schrauder; Ansgar Schulz; F R Schuster; Petr Sedlacek; Brigitte Strahm; Karl-Walter Sykora; Wilhelm Wössmann; Martin Zimmermann; Michael H Albert; Peter Bader; M G Sauer
Allo-SCT using BU, CY and melphalan for children with AML in second CR.
Bone marrow transplantation 2013;48(5):651-6.
2013: R Beier; Karoline Ehlert; Matthias Eyrich; Johann Greil; Bernd Gruhn; W Holter; Manfred Hönig; R Meisel; I Müller; W Nürnberger; M Sauer; Paul G Schlegel; Ansgar Schulz; K D Stachel; Meinolf Suttorp; Christian Urban; Wilhelm Wössmann; Martin Zimmermann; Peter Bader; Karl-Walter Sykora
Long-term follow-up of children conditioned with Treosulfan: German and Austrian experience.
Bone marrow transplantation 2013;48(4):491-501.
2013: Vanya Icheva; Simone Kayser; Christina Kyzirakos; Peter Lang; Michaela Nathrath; Michael Schumm; Wolfgang Schwinger; Stefan Stevanovic; Sebastian Tuve; Daniel Wolff; Michael H Albert; Wolfgang A Bethge; Johann Greil; Rupert Handgretinger; Tobias Feuchtinger
Adoptive transfer of epstein-barr virus (EBV) nuclear antigen 1-specific t cells as treatment for EBV reactivation and lymphoproliferative disorders after allogeneic stem-cell transplantation.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2013;31(1):39-48.
2011: Patrick Schlegel; Paul-Gerhard Schlegel; Michael Schumm; Heiko-Manuel Teltschik; Peter Bader; Tobias Feuchtinger; Johann Greil; Rupert Handgretinger; Thomas Klingebiel; Ewa Koscielniak; Matthias Pfeiffer; Peter Lang
Long-term IL-2 therapy after transplantation of T cell depleted stem cells from alternative donors in children.
Best practice & research. Clinical haematology 2011;24(3):443-52.
2011: Peter Lang; Matthias Pfeiffer; Patrick Schlegel; Paul-Gerhard Schlegel; Heiko-Manuel Teltschik; Peter Bader; James Beck; Martin Ebinger; Tobias Feuchtinger; Johann Greil; Thomas Klingebiel; Rupert Handgretinger
Natural killer cell activity influences outcome after T cell depleted stem cell transplantation from matched unrelated and haploidentical donors.
Best practice & research. Clinical haematology 2011;24(3):403-11.
2010: Michael H Albert; A R Gennery; Johann Greil; C M Cale; Krzysztof Kalwak; I Kondratenko; W Mlynarski; Gundula Notheis; Monika Führer; Irene Schmid; Bernd H Belohradsky
Successful SCT for Nijmegen breakage syndrome.
Bone marrow transplantation 2010;45(4):622-6.
2010: Ulrich Pannicke; Manfred Hönig; Ilka Schulze; Jan Rohr; Gitta A Heinz; Sylvia Braun; Ingrid Janz; Eva-Maria Rump; Markus G Seidel; Susanne Matthes-Martin; Jan Soerensen; Johann Greil; Daniel K Stachel; Bernd H Belohradsky; Michael H Albert; Ansgar Schulz; Stephan Ehl; Wilhelm Friedrich; Klaus Schwarz
The most frequent DCLRE1C (ARTEMIS) mutations are based on homologous recombination events.
Human mutation 2010;31(2):197-207.
2009: Kaan Boztug; Giridharan Appaswamy; Angel Ashikov; Alejandro A Schäffer; Ulrich Salzer; Jana Diestelhorst; Manuela Germeshausen; Gudrun Brandes; Jacqueline Lee-Gossler; Fatih Noyan; Anna-Katherina Gatzke; Milen Minkov; Johann Greil; Christian Kratz; Theoni Petropoulou; Isabelle Pellier; Christine Bellanné-Chantelot; Nima Rezaei; Kirsten Mönkemöller; Noha Irani-Hakimeh; Hans Bakker; Rita Gerardy-Schahn; Cornelia Zeidler; Bodo Grimbacher; Karl Welte; Christoph Klein
A syndrome with congenital neutropenia and mutations in G6PC3.
The New England journal of medicine 2009;360(1):32-43.
2008: Julia Stieglmaier; Edwin Bremer; Christian Kellner; Tanja M Liebig; Bram ten Cate; Matthias Peipp; Hendrik Schulze-Koops; Matthias Pfeiffer; Hans-Jörg Bühring; Johann Greil; Fuat Oduncu; Bertold Emmerich; Georg H Fey; Wijnand Helfrich
Selective induction of apoptosis in leukemic B-lymphoid cells by a CD19-specific TRAIL fusion protein.
Cancer immunology, immunotherapy : CII 2008;57(2):233-46.
2008: Peter Lang; Ingo Mueller; Johann Greil; Peter Bader; Michael Schumm; Matthias Pfeiffer; Walter Hoelle; Thomas Klingebiel; Frank Heinzelmann; Claus Belka; Paul G Schlegel; Bernhard Kremens; Willi Woessmann; Rupert Handgretinger
Retransplantation with stem cells from mismatched related donors after graft rejection in pediatric patients.
Blood cells, molecules & diseases 2008;40(1):33-9.
2006: Ricardo A Dewey; Inés Avedillo Díez; Matthias Ballmaier; Alexandra H Filipovich; Johann Greil; Tayfun Güngör; Christoph Happel; Alexey Maschan; Fatih Noyan; Ulrich Pannicke; Klaus Schwarz; Scott Snapper; Karl Welte; Christoph Klein
Retroviral WASP gene transfer into human hematopoietic stem cells reconstitutes the actin cytoskeleton in myeloid progeny cells differentiated in vitro.
Experimental hematology 2006;34(9):1161-9.
2006: Maria Thomas; Johann Greil; Olaf Heidenreich
Targeting leukemic fusion proteins with small interfering RNAs: recent advances and therapeutic potentials.
Acta pharmacologica Sinica 2006;27(3):273-81.
2005: Maria Thomas; Andreas Gessner; Hans-Peter Vornlocher; Philipp Hadwiger; Johann Greil; Olaf Heidenreich
Targeting MLL-AF4 with short interfering RNAs inhibits clonogenicity and engraftment of t(4;11)-positive human leukemic cells.
Blood 2005;106(10):3559-66.
2005: Tobias Feuchtinger; Celine Richard; Matthias Pfeiffer; F Neuhäuser; J Lücke; Rupert Handgretinger; Johann Greil; Peter Bader; Thomas Klingebiel; Paul G Schlegel; Gerhard Jahn; Dietrich Niethammer; Peter Lang
Adenoviral infections after transplantation of positive selected stem cells from haploidentical donors in children: an update.
Klinische Pädiatrie 2005;217(6):339-44.
2005: Peter Lang; Michael Schumm; Johann Greil; Peter Bader; Thomas Klingebiel; I Müller; Tobias Feuchtinger; Matthias Pfeiffer; Paul G Schlegel; Dietrich Niethammer; Rupert Handgretinger
A comparison between three graft manipulation methods for haploidentical stem cell transplantation in pediatric patients: preliminary results of a pilot study.
Klinische Pädiatrie 2005;217(6):334-8.
2005: Matthias Pfeiffer; S Stanojevic; Tobias Feuchtinger; Johann Greil; Rupert Handgretinger; Karin Barbin; G Jung; D Martin; Dietrich Niethammer; Peter Lang
Rituximab mediates in vitro antileukemic activity in pediatric patients after allogeneic transplantation.
Bone marrow transplantation 2005;36(2):91-7.
2005: Thomas Klingebiel; Peter Lang; Michael Schumm; Ulrike Koehl; Peter Bader; Dirk Schwabe; Paul G Schlegel; Matthias Eyrich; Johann Greil; James F Beck; Dietrich Niethammer; Rupert Handgretinger
Experiences with haploidentical stem cell transplantation in children with acute lymphoblastic leukemia.
Pathologie-biologie 2005;53(3):159-61.
2005: Martin Ebinger; Thomas Bock; Reinhard Kandolf; Karl Sotlar; Burkhard D Bültmann; Johann Greil
Standard mono- and dinucleotide repeats do not appear to be sensitive markers of microsatellite instability in the Ewing family of tumors.
Cancer genetics and cytogenetics 2005;157(2):189-90.
2005: Tobias Feuchtinger; Julia Lücke; Klaus Hamprecht; Celine Richard; Rupert Handgretinger; Michael Schumm; Johann Greil; Thomas Bock; Dietrich Niethammer; Peter Lang
Detection of adenovirus-specific T cells in children with adenovirus infection after allogeneic stem cell transplantation.
British journal of haematology 2005;128(4):503-9.
2004: Peter Lang; Johann Greil; Peter Bader; Rupert Handgretinger; Thomas Klingebiel; Michael Schumm; Paul G Schlegel; Tobias Feuchtinger; Matthias Pfeiffer; Hans Scheel-Walter; Monika Führer; David Martin; Dietrich Niethammer
Long-term outcome after haploidentical stem cell transplantation in children.
Blood cells, molecules & diseases 2004;33(3):281-7.
2004: Peter Lang; Karin Barbin; Tobias Feuchtinger; Johann Greil; Matthias Peipp; Susan J Zunino; Matthias Pfeiffer; Rupert Handgretinger; Dietrich Niethammer; Georg H Fey
Chimeric CD19 antibody mediates cytotoxic activity against leukemic blasts with effector cells from pediatric patients who received T-cell-depleted allografts.
Blood 2004;103(10):3982-5.
2004: Peter Lang; A Griesinger; Klaus Hamprecht; Tobias Feuchtinger; Michael Schumm; F Neuhäuser; Johann Greil; D Martin; Rupert Handgretinger; Dietrich Niethammer
Antiviral activity against CMV-infected fibroblasts in pediatric patients transplanted with CD34(+)-selected allografts from alternative donors.
Human immunology 2004;65(5):423-31.
2004: Peter Bader; Hermann Kreyenberg; Walter Hoelle; Gregor Dueckers; Rupert Handgretinger; Peter Lang; Bernhard Kremens; Dagmar Dilloo; Karl-Walter Sykora; Martin Schrappe; Charlotte Niemeyer; Arend von Stackelberg; Bernd Gruhn; Günter Henze; Johann Greil; Dietrich Niethammer; Klaus Dietz; James F Beck; Thomas Klingebiel
Increasing mixed chimerism is an important prognostic factor for unfavorable outcome in children with acute lymphoblastic leukemia after allogeneic stem-cell transplantation: possible role for pre-emptive immunotherapy?
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2004;22(9):1696-705.
2004: Peter Bader; Hermann Kreyenberg; Walter Hoelle; Gregor Dueckers; Bernhard Kremens; Dagmar Dilloo; Karl-Walter Sykora; Charlotte Niemeyer; Dirk Reinhardt; Josef Vormoor; Bernd Gruhn; Peter Lang; Johann Greil; Rupert Handgretinger; Dietrich Niethammer; Thomas Klingebiel; James F Beck
Increasing mixed chimerism defines a high-risk group of childhood acute myelogenous leukemia patients after allogeneic stem cell transplantation where pre-emptive immunotherapy may be effective.
Bone marrow transplantation 2004;33(8):815-21.
2004: P Lang; T Klingebiel; Michael Schumm; R Handgretinger; Johann Greil; James F Beck; D Niethammer; P Bader
Correction of persistent thrombocytopenia by a boost of CD133+ selected stem cells in a patient transplanted for Wiskott-Aldrich syndrome 10 years ago.
Bone marrow transplantation 2004;33(8):879-80.
2004: Tobias Feuchtinger; Peter Lang; Klaus Hamprecht; Michael Schumm; Johann Greil; Gerhard Jahn; Dietrich Niethammer; Hermann Einsele
Isolation and expansion of human adenovirus-specific CD4+ and CD8+ T cells according to IFN-gamma secretion for adjuvant immunotherapy.
Experimental hematology 2004;32(3):282-9.
2004: Peter Lang; Thomas Klingebiel; Peter Bader; Johann Greil; Michael Schumm; Paul G Schlegel; Matthias Eyrich; S Mueller-Weihrich; Dietrich Niethammer; Rupert Handgretinger
Transplantation of highly purified peripheral-blood CD34+ progenitor cells from related and unrelated donors in children with nonmalignant diseases.
Bone marrow transplantation 2004;33(1):25-32.
2004: Peter Lang; Peter Bader; Michael Schumm; Tobias Feuchtinger; Hermann Einsele; Monika Führer; Christof Weinstock; Rupert Handgretinger; Selim Kuci; David Martin; Dietrich Niethammer; Johann Greil
Transplantation of a combination of CD133+ and CD34+ selected progenitor cells from alternative donors.
British journal of haematology 2004;124(1):72-9.
2004: Selim Corbacioglu; Johann Greil; Christina Peters; Nico M Wulffraat; Hans-Jürgen Laws; Dagmar Dilloo; B Straham; Ute Gross-Wieltsch; Karl-Walter Sykora; A Ridolfi-Lüthy; O Basu; Bernd Gruhn; Tayfun Güngör; Walter A Mihatsch; Ansgar S Schulz; B Strahm
Defibrotide in the treatment of children with veno-occlusive disease (VOD): a retrospective multicentre study demonstrates therapeutic efficacy upon early intervention.
Bone marrow transplantation 2004;33(2):189-95.
2004: P Lang; R Handgretinger; Johann Greil; P Bader; Michael Schumm; T Klingebiel; D Niethammer
Transplantation of CD34+ enriched allografts in children with nonmalignant diseases: does graft manipulation necessarily result in high incidence of graft failure?
Bone marrow transplantation 2004;33(1):125-6; author reply 127.
2003: M Koch; Peter Lang; Peter Bader; Hermann Kreyenberg; Michael Schumm; Hans Scheel-Walter; A Hochhaus; Dietrich Niethammer; Johann Greil
Successful unrelated allogeneic stem cell transplantation after treatment of lymphoid blast crisis CML with imatinib and imatinib-containing conditioning regimen in a 16-year-old male.
Bone marrow transplantation 2003;32(5):541-2.
2003: Matthias Eyrich; Christine Leiler; Peter Lang; Karin Schilbach; Michael Schumm; Peter Bader; Johann Greil; Thomas Klingebiel; Rupert Handgretinger; Dietrich Niethammer; Paul G Schlegel
A prospective comparison of immune reconstitution in pediatric recipients of positively selected CD34+ peripheral blood stem cells from unrelated donors vs recipients of unmanipulated bone marrow from related donors.
Bone marrow transplantation 2003;32(4):379-90.
2003: Peter Lang; Rupert Handgretinger; Dietrich Niethammer; Paul G Schlegel; Michael Schumm; Johann Greil; Peter Bader; Corinna Engel; Hans Scheel-Walter; Matthias Eyrich; Thomas Klingebiel
Transplantation of highly purified CD34+ progenitor cells from unrelated donors in pediatric leukemia.
Blood 2003;101(4):1630-6.
2002: Matthias Peipp; Heide Küpers; Domenica Saul; Beate Schlierf; Johann Greil; Susan J Zunino; Martin Gramatzki; Georg H Fey
A recombinant CD7-specific single-chain immunotoxin is a potent inducer of apoptosis in acute leukemic T cells.
Cancer research 2002;62(10):2848-55.
2002: Peter Bader; G Dückers; Hermann Kreyenberg; Walter Hoelle; Gunter Kerst; Peter Lang; Johann Greil; Dietrich Niethammer; L F Beck; Thomas Klingebiel
Monitoring of donor cell chimerism for the detection of relapse and early immunotherapeutic intervention in acute lymphoblastic leukemias.
Annals of hematology 2002;81 Suppl 2():S25-7.
2001: Martin Reichel; E Gillert; Sabine Angermüller; J P Hensel; F Heidel; M Lode; Thomas Leis; Andrea Biondi; Oskar A Haas; Sabine Strehl; E Renate Panzer-Grümayer; F Griesinger; Jörn D Beck; Johann Greil; Georg H Fey; fatih uckun; Rolf Marschalek
Biased distribution of chromosomal breakpoints involving the MLL gene in infants versus children and adults with t(4;11) ALL.
Oncogene 2001;20(23):2900-7.
2001: Rupert Handgretinger; Thomas Klingebiel; Peter Lang; Michael Schumm; S Neu; A Geiselhart; Peter Bader; Paul G Schlegel; Johann Greil; D Stachel; R J Herzog; Dietrich Niethammer
Megadose transplantation of purified peripheral blood CD34(+) progenitor cells from HLA-mismatched parental donors in children.
Bone marrow transplantation 2001;27(8):777-83.
2001: H Hertzberg; Bernhard Kremens; Isabel Velten; J D Beck; Johann Greil
Recurrent disseminated retinoblastoma in a 7-year-old girl treated successfully by high-dose chemotherapy and CD34-selected autologous peripheral blood stem cell transplantation.
Bone marrow transplantation 2001;27(6):653-5.
2001: Martin Reichel; E Gillert; I Breitenlohner; Sabine Angermüller; Georg H Fey; Rolf Marschalek; Roland Repp; Johann Greil; Jörn D Beck
Rapid isolation of chromosomal breakpoints from patients with t(4;11) acute lymphoblastic leukemia: implications for basic and clinical research.
Leukemia 2001;15(2):286-8.
1999: Jan Dörrie; Wolfgang Schuh; A Keil; E Bongards; Johann Greil; Georg H Fey; Susan J Zunino
Regulation of CD95 expression and CD95-mediated cell death by interferon-gamma in acute lymphoblastic leukemia with chromosomal translocation t(4;11).
Leukemia 1999;13(10):1539-47.
1999: E Gillert; Thomas Leis; Roland Repp; Martin Reichel; A Hösch; I Breitenlohner; Sabine Angermüller; Arndt Borkhardt; Jochen Harbott; Fritz H Lampert; F Griesinger; Johann Greil; Georg H Fey; Rolf Marschalek
A DNA damage repair mechanism is involved in the origin of chromosomal translocations t(4;11) in primary leukemic cells.
Oncogene 1999;18(33):4663-71.
1999: Martin Reichel; E Gillert; I Breitenlohner; Roland Repp; Johann Greil; Jörn D Beck; Georg H Fey; Rolf Marschalek
Rapid isolation of chromosomal breakpoints from patients with t(4;11) acute lymphoblastic leukemia: implications for basic and clinical research.
Cancer research 1999;59(14):3357-62.
1999: Rupert Handgretinger; Michael Schumm; Peter Lang; Johann Greil; A Reiter; Peter Bader; Dietrich Niethammer; Thomas Klingebiel
Transplantation of megadoses of purified haploidentical stem cells.
Annals of the New York Academy of Sciences 1999;872():351-61; discussion 361-2.
1998: Martin Reichel; E Gillert; I Nilson; Gabriele Siegler; Johann Greil; Georg H Fey; Rolf Marschalek
Fine structure of translocation breakpoints in leukemic blasts with chromosomal translocation t(4;11): the DNA damage-repair model of translocation.
Oncogene 1998;17(23):3035-44.
1997: Rolf Marschalek; I Nilson; K Löchner; R Greim; Gabriele Siegler; Johann Greil; Jörn D Beck; Georg H Fey
The structure of the human ALL-1/MLL/HRX gene.
Leukemia & lymphoma 1997;27(5-6):417-28.
1997: I Nilson; Martin Reichel; Maria Grazia Ennas; R Greim; Constanze Knörr-Wittmann; Gabriele Siegler; Johann Greil; Georg H Fey; Rolf Marschalek
Exon/intron structure of the human AF-4 gene, a member of the AF-4/LAF-4/FMR-2 gene family coding for a nuclear protein with structural alterations in acute leukaemia.
British journal of haematology 1997;98(1):157-69.
1997: Rupert Handgretinger; Johann Greil; U Schürmann; Peter Lang; O Gonzalez-Ramella; I Schmidt; R Führer; Dietrich Niethammer; Thomas Klingebiel
Positive selection and transplantation of peripheral CD34+ progenitor cells: feasibility and purging efficacy in pediatric patients with neuroblastoma.
Journal of hematotherapy 1997;6(3):235-42.