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Andreas Greinacher

Research Profile

Disorders

Thrombocytopenia

Chemicals & Drugs

Anatomy

Concepts & Ideas

Physiology

Platelet Activation

Procedures

Hirudin Therapy

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Publications

TOP 3
Thomas Thiele; Nancy Heddle; Andreas Greinacher
Pooled platelet concentrates or apheresis platelets?
Tamam Bakchoul; Sven Brandt; Mihaela Delcea; Thomas Kohlmann; Simon Panzer; Ulrich J H Sachs; Sixten Selleng; Theodore E Warkentin; Heike Zöllner; Jean Amiral; Andreas Greinacher
Anti-protamine-heparin antibodies: incidence, clinical relevance, and pathogenesis.
Francesco Rodeghiero; Marco Ruggeri; Alberto Tosetto; Victor Blanchette; James B Bussel; Douglas B Cines; Nichola Cooper; Terry Gernsheimer; Bertrand Godeau; Andreas Greinacher; Paul Imbach; Mehdi Khellaf; Robert J Klaassen; Thomas Kühne; Howard Liebman; Maria Gabriella Mazzucconi; Marc Michel; Adrian Newland; Ingrid Pabinger; Roberto Stasi
Standardization of bleeding assessment in immune thrombocytopenia: report from the International Working Group.

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All Publications

2013: Thomas Thiele; Nancy Heddle; Andreas Greinacher
Pooled platelet concentrates or apheresis platelets?
The New England journal of medicine 2013;368(19):1849.
2013: Tamam Bakchoul; Sven Brandt; Mihaela Delcea; Thomas Kohlmann; Simon Panzer; Ulrich J H Sachs; Sixten Selleng; Theodore E Warkentin; Heike Zöllner; Jean Amiral; Andreas Greinacher
Anti-protamine-heparin antibodies: incidence, clinical relevance, and pathogenesis.
Blood 2013;121(15):2821-7.
2013: Francesco Rodeghiero; Marco Ruggeri; Alberto Tosetto; Victor Blanchette; James B Bussel; Douglas B Cines; Nichola Cooper; Terry Gernsheimer; Bertrand Godeau; Andreas Greinacher; Paul Imbach; Mehdi Khellaf; Robert J Klaassen; Thomas Kühne; Howard Liebman; Maria Gabriella Mazzucconi; Marc Michel; Adrian Newland; Ingrid Pabinger; Roberto Stasi
Standardization of bleeding assessment in immune thrombocytopenia: report from the International Working Group.
Blood 2013;121(14):2596-606.
2013: Karina Althaus; Rosanna Abbate; Simon Davidson; Andreas Greinacher; Gregor Hron; Angela Rogolino; Ulrike Strobel; Tamam Bakchoul
Evaluation of automated immunoassays in the diagnosis of heparin induced thrombocytopenia.
Thrombosis research 2013;131(3):e85-90.
2013: Thomas Thiele; Nancy Heddle; Andreas Greinacher
Donor exposures in recipients of pooled platelet concentrates.
The New England journal of medicine 2013;368(5):487-9.
2013: Andreas Greinacher; Birgitt Fürll; Sixten Selleng
Heparin-induced thrombocytopenia.
Methods in molecular biology (Clifton, N.J.) 2013;992():301-18.
2012: Thomas Thiele; Uwe Völker; Birgit Fürll; Manuela Gesell Salazar; Andreas Greinacher; Cristina Iuga; Susann Janetzky; Hansjorg Schwertz; Leif Steil
Early storage lesions in apheresis platelets are induced by the activation of the integrin αIIbβ₃ and focal adhesion signaling pathways.
Journal of proteomics 2012;76 Spec No.():297-315.
2012: Christian Pötschke; Sixten Selleng; Barbara M Bröker; Andreas Greinacher
Heparin-induced thrombocytopenia: further evidence for a unique immune response.
Blood 2012;120(20):4238-45.
2012: Krystin Krauel; Uwe Mamat; Claudia Weber; Ulrich Zähringer; Sven Brandt; Andreas Greinacher; Sven Hammerschmidt
Platelet factor 4 binding to lipid A of Gram-negative bacteria exposes PF4/heparin-like epitopes.
Blood 2012;120(16):3345-52.
2012: Andreas Greinacher; Krystin Krauel; Inga Jensch
HIT-antibodies promote their own antigen.
Blood 2012;120(5):930-1.
2012: Tamam Bakchoul; Andreas Greinacher
Recent advances in the diagnosis and treatment of heparin-induced thrombocytopenia.
Therapeutic advances in hematology 2012;3(4):237-51.
2012: Konstanze Aurich; Birgitt Fürll; Andreas Greinacher; Norbert Hosten; Rabea Sietmann; Mark-Christopher Spoerl; Werner Weitschies
Development of a method for magnetic labeling of platelets.
Nanomedicine : nanotechnology, biology, and medicine 2012;8(5):537-44.
2012: Annett Quiel; Andreas Greinacher; Britta Jürgen; Susan Lassen; Sabine Witt; Ralf Wörl; Thomas Schweder
Sensitive detection of idiotypic platelet-reactive alloantibodies by an electrical protein chip.
Biosensors & bioelectronics 2012;36(1):207-11.
2012: Thomas Thiele; Uwe Völker; Tamam Bakchoul; Andrea Bente; Siegfried Görg; Andreas Greinacher; Christina Iuga; Armin Sablewski; Leif Steil
Profiling alterations in platelets induced by Amotosalen/UVA pathogen reduction and gamma irradiation--a LC-ESI-MS/MS-based proteomics approach.
Blood transfusion = Trasfusione del sangue 2012;10 Suppl 2():s63-70.
2012: Miriam E Jaax; Andreas Greinacher
Management of heparin-induced thrombocytopenia.
Expert opinion on pharmacotherapy 2012;13(7):987-1006.
2012: T Thiele; K Althaus; G Hron; C Müller; H W S Schroeder; A Sümnig; Andreas Greinacher
Platelet transfusion for reversal of dual antiplatelet therapy in patients requiring urgent surgery: a pilot study.
Journal of thrombosis and haemostasis : JTH 2012;10(5):968-71.
2012: Gabriele Jedlitschky; Andreas Greinacher; Heyo K Kroemer
Transporters in human platelets: physiologic function and impact for pharmacotherapy.
Blood 2012;119(15):3394-402.
2012: Catherine Léon; Fabien Pertuy; Patricia Laeuffer; Frank Dombrowski; Anita Eckly; Katja Evert; Christian Gachet; Andreas Greinacher
Romiplostim administration shows reduced megakaryocyte response-capacity and increased myelofibrosis in a mouse model of MYH9-RD.
Blood 2012;119(14):3333-41.
2012: Andreas Greinacher
Taking advantage of the non-anticoagulant effects of heparin.
Thrombosis and haemostasis 2012;107(4):602.
2012: Donald M Arnold; Andreas Greinacher; S Santoso
Recommendations for the implementation of platelet autoantibody testing in clinical trials of immune thrombocytopenia.
Journal of thrombosis and haemostasis : JTH 2012;10(4):695-7.
2012: Adriano Alatri; Anna-Elina Armstrong; Andreas Greinacher; Andreas Koster; Sibylle A Kozek-Langenecker; Marcus D Lancé; Andreas Link; Jørn D Nielsen; Per M Sandset; Alexander J Spanjersberg; Michael Spannagl
Results of a consensus meeting on the use of argatroban in patients with heparin-induced thrombocytopenia requiring antithrombotic therapy - a European Perspective.
Thrombosis research 2012;129(4):426-33.
2012: Thomas Thiele; Theodore E Warkentin; Christina Wasner; Antje Wessel; Kathrin Zimmermann; Andreas Greinacher; Gregor Hron; Sarah Kellner; Matthias Nauck; Kathleen Selleng
Storage of thawed plasma for a liquid plasma bank: impact of temperature and methylene blue pathogen inactivation.
Transfusion 2012;52(3):529-36.
2012: Krystin Krauel; Christine Hackbarth; Birgitt Fürll; Andreas Greinacher
Heparin-induced thrombocytopenia: in vitro studies on the interaction of dabigatran, rivaroxaban, and low-sulfated heparin, with platelet factor 4 and anti-PF4/heparin antibodies.
Blood 2012;119(5):1248-55.
2012: Julia Gansler; Andreas Greinacher; Miriam Jaax; Silke Leiting; Bettina Appel; Silvia Fischer; Klaus T Preissner
Structural requirements for the procoagulant activity of nucleic acids.
PloS one 2012;7(11):e50399.
2011: Theodore E Warkentin; R H Aster; B H Chong; Andreas Greinacher; Y Gruel
Laboratory testing for heparin-induced thrombocytopenia: a conceptual framework and implications for diagnosis.
Journal of thrombosis and haemostasis : JTH 2011;9(12):2498-500.
2011: Andreas Greinacher
Immunogenic but effective: the HIT-fondaparinux brain puzzler.
Journal of thrombosis and haemostasis : JTH 2011;9(12):2386-8.
2011: Simon Gebhard; Manuela Gesell-Salazar; Kenneth J Clemetson; Elke Hammer; Beate Kuttler; Barbara Peters; Jörg Peters; Rainer Rettig; Christian Scharf; Leif Steil; Uwe Völker; Andreas Greinacher
Angiotensin II-dependent hypertension causes reversible changes in the platelet proteome.
Journal of hypertension 2011;29(11):2126-37.
2011: Stefan Muschter; Tom Berthold; Andreas Greinacher
Developments in the definition and clinical impact of human neutrophil antigens.
Current opinion in hematology 2011;18(6):452-60.
2011: Tobias Müller; Elisabeth Rumpel; Henny Wegner; Andreas Greinacher; Susanne Hradetzky; Antje Blumenthal; Frank Bollig; Karlhans Endlich; Nicole Endlich
Non-muscle myosin IIA is required for the development of the zebrafish glomerulus.
Kidney international 2011;80(10):1055-63.
2011: Tom Berthold; Jürgen Bux; Birgitt Fürll; Holger Hippe; Jens Hoppen; Kathleen Kuhnert; Stefan Muschter; Angelika Reil; Jan Wesche; Andreas Greinacher
Epitope mapping of antibodies directed against the human neutrophil alloantigen 3a.
Transfusion 2011;51(10):2160-7.
2011: Andreas Greinacher; Jan T Kielstein; Markus M Lerch; Peter Abel; Alexander Dressel; Friedlinde Ernst; Stephan B Felix; Michael Fiene; Sigrun Friesecke; Mario Schiffer; Bernhard M W Schmidt; Kathleen Selleng; Sylvia Stracke; Karin Weissenborn; Julia Mayerle
Treatment of severe neurological deficits with IgG depletion through immunoadsorption in patients with Escherichia coli O104:H4-associated haemolytic uraemic syndrome: a prospective trial.
Lancet 2011;378(9797):1166-73.
2011: Karina Althaus; Ulrike Strobel; Theodore E Warkentin; Andreas Greinacher
Combined use of the high heparin step and optical density to optimize diagnostic sensitivity and specificity of an anti-PF4/heparin enzyme-immunoassay.
Thrombosis research 2011;128(3):256-60.
2011: Andreas Greinacher; Sven Hammerschmidt; Birte Holtfreter; Till Ittermann; Krystin Krauel; Claudia Weber; Daniela Gätke; Thomas Kocher
Association of natural anti-platelet factor 4/heparin antibodies with periodontal disease.
Blood 2011;118(5):1395-401.
2011: Herbert Fluhr; Julia Spratte; Stephanie Heidrich; Jens Ehrhardt; Andreas Greinacher; Marek Zygmunt
The molecular charge and size of heparins determine their impact on the decidualization of human endometrial stromal cells.
Molecular human reproduction 2011;17(6):354-9.
2011: Andreas Greinacher
Platelet activation by heparin.
Blood 2011;117(18):4686-7.
2011: Sixten Selleng; Natalie Schreier; Hans-Georg Wollert; Andreas Greinacher
The diagnostic value of the anti-PF4/heparin immunoassay high-dose heparin confirmatory test in cardiac surgery patients.
Anesthesia and analgesia 2011;112(4):774-6.
2011: Andreas Greinacher; Konstanze Fendrich; Ralf Brzenska; Volker Kiefel; Wolfgang Hoffmann
Implications of demographics on future blood supply: a population-based cross-sectional study.
Transfusion 2011;51(4):702-9.
2011: Krystin Krauel; Christian Pötschke; Claudia Weber; Wolfram Kessler; Birgitt Fürll; Till Ittermann; Stefan Maier; Sven Hammerschmidt; Barbara M Bröker; Andreas Greinacher
Platelet factor 4 binds to bacteria, [corrected] inducing antibodies cross-reacting with the major antigen in heparin-induced thrombocytopenia.
Blood 2011;117(4):1370-8.
2011: Angelika Reil; Jan Wesche; Andreas Greinacher; Juergen Bux
Geno- and phenotyping and immunogenicity of HNA-3.
Transfusion 2011;51(1):18-24.
2010: Sebastian M Schellong; Sylvia Haas; Andreas Greinacher; Uta Schwanebeck; Christian Sieder; Claudia Abletshauser; Peter Bramlage; Hanno Riess
An open-label comparison of the efficacy and safety of certoparin versus unfractionated heparin for the prevention of thromboembolic complications in acutely ill medical patients: CERTAIN.
Expert opinion on pharmacotherapy 2010;11(18):2953-61.
2010: V Kiefel; Andreas Greinacher
[Differential diagnosis and treatment of thrombocytopenia].
Der Internist 2010;51(11):1397-410.
2010: T Thiele; K Althaus; Andreas Greinacher
[Heparin-induced thrombocytopenia].
Der Internist 2010;51(9):1127-32, 1134-5.
2010: Andreas Greinacher; T Ittermann; J Bagemühl; K Althaus; Birgitt Fürll; Sixten Selleng; Norbert Lubenow; S Schellong; J I Sheppard; Theodore E Warkentin
Heparin-induced thrombocytopenia: towards standardization of platelet factor 4/heparin antigen tests.
Journal of thrombosis and haemostasis : JTH 2010;8(9):2025-31.
2010: Sixten Selleng; Birgit Malowsky; Till Itterman; Jessica Bagemühl; Antje Wessel; Hans-Georg Wollert; Theodore E Warkentin; Andreas Greinacher
Incidence and clinical relevance of anti-platelet factor 4/heparin antibodies before cardiac surgery.
American heart journal 2010;160(2):362-9.
2010: Thomas Thiele; Leif Steil; Uwe Völker; Andreas Greinacher
Transfusion medicine and proteomics. Alliance or coexistence?
Blood transfusion = Trasfusione del sangue 2010;8 Suppl 3():s16-25.
2010: Juliane Niessen; Gabriele Jedlitschky; Markus Grube; Hirotaka Kawakami; Junichi Kamiie; Sumio Ohtsuki; Hansjörg Schwertz; Sandra Bien; Katharina Starke; Christoph Ritter; Ulrike Strobel; Andreas Greinacher; Tetsuya Terasaki; Heyo K Kroemer
Expression of ABC-type transport proteins in human platelets.
Pharmacogenetics and genomics 2010;20(6):396-400.
2010: Mark A Crowther; Deborah J Cook; Martin Albert; David Williamson; Maureen Meade; John T Granton; Yoanna Skrobik; Stephan Langevin; Sangeeta Mehta; Paul Hebert; Gordon H Guyatt; William Geerts; Christian G Rabbat; James D Douketis; Nicole Zytaruk; Joanne Sheppard; Andreas Greinacher; Theodore E Warkentin
The 4Ts scoring system for heparin-induced thrombocytopenia in medical-surgical intensive care unit patients.
Journal of critical care 2010;25(2):287-93.
2010: Matthias Thielmann; Marlene Bunschkowski; Paschalis Tossios; Sixten Selleng; Günter Marggraf; Andreas Greinacher; Heinz Jakob; Parwis Massoudy
Perioperative thrombocytopenia in cardiac surgical patients - incidence of heparin-induced thrombocytopenia, morbidities and mortality.
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 2010;37(6):1391-5.
2010: Hansjörg Schwertz; Sarah Köster; Walter H A Kahr; Noemi Michetti; Bjoern F Kraemer; David A Weitz; Robert C Blaylock; Larry W Kraiss; Andreas Greinacher; Guy A Zimmerman; Andrew S Weyrich
Anucleate platelets generate progeny.
Blood 2010;115(18):3801-9.
2010: J Lange; Kathleen Selleng; N M Heddle; A Traore; Andreas Greinacher
Coombs' crossmatch after negative antibody screening--a retrospective observational study comparing the tube test and the microcolumn technology.
Vox sanguinis 2010;98(3 Pt 1):e269-75.
2010: A Staudt; L R Herda; Christiane Trimpert; L Lubenow; Martin Landsberger; Marcus Dörr; Astrid Hummel; L G Eckerle; D Beug; C Müller; W Hoffmann; K Weitmann; Karin Klingel; Reinhard Kandolf; Heyo K Kroemer; Andreas Greinacher; Stephan B Felix
Fcgamma-receptor IIa polymorphism and the role of immunoadsorption in cardiac dysfunction in patients with dilated cardiomyopathy.
Clinical pharmacology and therapeutics 2010;87(4):452-8.
2010: Norbert Lubenow; Peter Hinz; Simone Thomaschewski; Theresia Lietz; Michael Vogler; Andrea Ladwig; Michael Jünger; Matthias Nauck; Sebastian Schellong; Kathrin Wander; Georg Engel; Axel Ekkernkamp; Andreas Greinacher
The severity of trauma determines the immune response to PF4/heparin and the frequency of heparin-induced thrombocytopenia.
Blood 2010;115(9):1797-803.
2010: Juliane Niessen; Gabriele Jedlitschky; Andreas Greinacher; Heyo K Kroemer
Isolation of platelet granules.
Current protocols in cell biology / editorial board, Juan S. Bonifacino ... [et al.] 2010;Chapter 3():Unit 3.35.
2010: Gabriele Jedlitschky; Marco Cattaneo; Lena E Lubenow; Dieter Rosskopf; Anna Lecchi; Andrea Artoni; Giovanna Motta; Juliane Niessen; Heyo K Kroemer; Andreas Greinacher
Role of MRP4 (ABCC4) in platelet adenine nucleotide-storage: evidence from patients with delta-storage pool deficiencies.
The American journal of pathology 2010;176(3):1097-103.
2010: Theodore E Warkentin; Richard J Cook; V J Marder; Andreas Greinacher
Anti-PF4/heparin antibody formation postorthopedic surgery thromboprophylaxis: the role of non-drug risk factors and evidence for a stoichiometry-based model of immunization.
Journal of thrombosis and haemostasis : JTH 2010;8(3):504-12.
2010: Andreas Greinacher
Opposites attract.
Blood 2010;115(3):440-1.
2010: Andreas Greinacher; Kathleen Selleng
Thrombocytopenia in the intensive care unit patient.
Hematology / the Education Program of the American Society of Hematology. American Society of Hematology. Education Program 2010;2010():135-43.
2010: Axel Matzdorff; Aristoteles Giagounidis; Andreas Greinacher; Erhard Hiller; Volker Kiefel; Hannes Müller-Beissenhirtz; Helmut Ostermann; Mathias Rummel; Ulrich J Sachs; Abdulgabar Salama
[Diagnosis and therapy of autoimmune thrombocytopenia. Recommendations of a joint Expert Group of DGHO, DGTI, DTH].
Onkologie 2010;33 Suppl 3():2-20.
2010: Andreas Greinacher; K Althaus; K Krauel; Sixten Selleng
Heparin-induced thrombocytopenia.
Hämostaseologie 2010;30(1):17-8, 20-8.
2010: Andreas Greinacher; Jan Wesche; Elke Hammer; Birgitt Fürll; Uwe Völker; Angelika Reil; Jürgen Bux
Characterization of the human neutrophil alloantigen-3a.
Nature medicine 2010;16(1):45-8.
2010: Sixten Selleng; B Malowsky; Ulrike Strobel; Antje Wessel; T Ittermann; Hans-Georg Wollert; Theodore E Warkentin; Andreas Greinacher
Early-onset and persisting thrombocytopenia in post-cardiac surgery patients is rarely due to heparin-induced thrombocytopenia, even when antibody tests are positive.
Journal of thrombosis and haemostasis : JTH 2010;8(1):30-6.
2010: Kathleen Selleng; Antje Schütt; Sixten Selleng; Theodore E Warkentin; Andreas Greinacher
Studies of the anti-platelet factor 4/heparin immune response: adapting the enzyme-linked immunosorbent spot assay for detection of memory B cells against complex antigens.
Transfusion 2010;50(1):32-9.
2009: Peter Hinz; Norbert Lubenow; Antje Wessel; Andreas Greinacher; Axel Ekkernkamp
[Thrombosis prophylaxis in trauma surgery units in Germany: a survey].
Der Unfallchirurg 2009;112(12):1029-33.
2009: Kathleen Selleng; Theodore E Warkentin; Jo-Ann I Sheppard; Andreas Greinacher
Immune mechanisms in heparin-induced thrombocytopenia: no evidence for immunoglobulin M anti-idiotype antibodies.
Transfusion 2009;49(9):1812-8.
2009: Andreas Greinacher; Birgitt Fuerll; Heike Zinke; Bernd Müllejans; William Krüger; Noemi Michetti; Wolfgang Motz; Hansjörg Schwertz
Megakaryocyte impairment by eptifibatide-induced antibodies causes prolonged thrombocytopenia.
Blood 2009;114(6):1250-3.
2009: Andreas Greinacher
Heparin-induced thrombocytopenia.
Journal of thrombosis and haemostasis : JTH 2009;7 Suppl 1():9-12.
2009: Sixten Selleng; Andreas Greinacher; Till Ittermann; Hans-Georg Wollert
Heparin/PF4 antibodies formation after heparin treatment: temporal aspects and long-term follow-up.
American heart journal 2009;158(1):e15.
2009: Rachel Pauzner; Andreas Greinacher; K Selleng; K Althaus; Boris Shenkman; Uri Seligsohn
False-positive tests for heparin-induced thrombocytopenia in patients with antiphospholipid syndrome and systemic lupus erythematosus.
Journal of thrombosis and haemostasis : JTH 2009;7(7):1070-4.
2009: Lena Oevermann; Jan Scheitz; Katharina Starke; Kathleen Köck; Thomas Kiefer; Gottfried Dölken; Juliane Niessen; Andreas Greinacher; Werner Siegmund; Marek Zygmunt; Heyo K Kroemer; Gabriele Jedlitschky; Christoph A Ritter
Hematopoietic stem cell differentiation affects expression and function of MRP4 (ABCC4), a transport protein for signaling molecules and drugs.
International journal of cancer. Journal international du cancer 2009;124(10):2303-11.
2009: Andreas Greinacher; Thomas Kohlmann; Ulrike Strobel; Jo-Ann I Sheppard; Theodore E Warkentin
The temporal profile of the anti-PF4/heparin immune response.
Blood 2009;113(20):4970-6.
2009: Theodore E Warkentin; Andreas Greinacher; Andreas Koster
Heparin-induced thrombocytopenia in patients with ventricular assist devices: are new prevention strategies required?
The Annals of thoracic surgery 2009;87(5):1633-40.
2009: Juliane Niessen; Gabriele Jedlitschky; Markus Grube; Sandra Bien; Hansjörg Schwertz; Sumio Ohtsuki; Hirotaka Kawakami; Junichi Kamiie; Stefan Oswald; Katharina Starke; Ulrike Strobel; Werner Siegmund; Dieter Rosskopf; Andreas Greinacher; Tetsuya Terasaki; Heyo K Kroemer
Human platelets express organic anion-transporting peptide 2B1, an uptake transporter for atorvastatin.
Drug metabolism and disposition: the biological fate of chemicals 2009;37(5):1129-37.
2009: Karina Althaus; Andreas Greinacher
MYH9-related platelet disorders.
Seminars in thrombosis and hemostasis 2009;35(2):189-203.
2009: Theodore E Warkentin; Andreas Greinacher
Heparin-induced anaphylactic and anaphylactoid reactions: two distinct but overlapping syndromes.
Expert opinion on drug safety 2009;8(2):129-44.
2009: Andreas Greinacher; J Bux; A Salama
[Autoimmune thrombocytopenia, neutropenia and hemolysis].
Der Internist 2009;50(3):276-90.
2009: Sixten Selleng; Kathleen Selleng; C Zawadzinski; Hans-Georg Wollert; S Yürek; Andreas Greinacher
Management of emergency cardiac surgery in a patient with alloanti-Ge2.
Transfusion medicine (Oxford, England) 2009;19(1):50-2.
2008: Sixten Selleng; Assad Haneya; Stephan Hirt; Kathleen Selleng; Christof Schmid; Andreas Greinacher
Management of anticoagulation in patients with subacute heparin-induced thrombocytopenia scheduled for heart transplantation.
Blood 2008;112(10):4024-7.
2008: Victor Agmo Hernández; Juliane Niessen; Falk Harnisch; Stephan Block; Andreas Greinacher; Heyo K Kroemer; Christiane A Helm; Fritz Scholz
The adhesion and spreading of thrombocyte vesicles on electrode surfaces.
Bioelectrochemistry (Amsterdam, Netherlands) 2008;74(1):210-6.
2008: Leif Steil; Thomas Thiele; Elke Hammer; Jürgen Bux; Monika Kalus; Uwe Völker; Andreas Greinacher
Proteomic characterization of freeze-dried human plasma: providing treatment of bleeding disorders without the need for a cold chain.
Transfusion 2008;48(11):2356-63.
2008: Andreas Greinacher; Theodore E Warkentin
Risk of heparin-induced thrombocytopenia in patients receiving thromboprophylaxis.
Expert review of hematology 2008;1(1):75-85.
2008: Andreas Greinacher; Theodore E Warkentin
Contaminated heparin.
The New England journal of medicine 2008;359(12):1291-2; author reply 1293.
2008: Federico Pappalardo; Andreas Greinacher; Sixten Selleng
Postoperative complications after cardiac surgery and HIT: a word of caution.
The Annals of thoracic surgery 2008;86(3):1054-5; author reply 1055.
2008: Andreas Greinacher; Jerrold H Levy
HIT happens: diagnosing and evaluating the patient with heparin-induced thrombocytopenia.
Anesthesia and analgesia 2008;107(2):356-8.
2008: Kathleen Selleng; Sixten Selleng; Andreas Greinacher
Heparin-induced thrombocytopenia in intensive care patients.
Seminars in thrombosis and hemostasis 2008;34(5):425-38.
2008: Theodore E Warkentin; Andreas Greinacher; Andreas Koster; A Michael Lincoff
Treatment and prevention of heparin-induced thrombocytopenia: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition).
Chest 2008;133(6 Suppl):340S-380S.
2008: Theodore E Warkentin; Andreas Greinacher; Andreas Koster
Bivalirudin.
Thrombosis and haemostasis 2008;99(5):830-9.
2008: Andreas Greinacher; Theodore E Warkentin
The direct thrombin inhibitor hirudin.
Thrombosis and haemostasis 2008;99(5):819-29.
2008: Sixten Selleng; Kathleen Selleng; Hans-Georg Wollert; B Muellejans; Theresia Lietz; Theodore E Warkentin; Andreas Greinacher
Heparin-induced thrombocytopenia in patients requiring prolonged intensive care unit treatment after cardiopulmonary bypass.
Journal of thrombosis and haemostasis : JTH 2008;6(3):428-35.
2008: Andreas Greinacher; S Alban; M A Omer-Adam; Werner Weitschies; Theodore E Warkentin
Heparin-induced thrombocytopenia: a stoichiometry-based model to explain the differing immunogenicities of unfractionated heparin, low-molecular-weight heparin, and fondaparinux in different clinical settings.
Thrombosis research 2008;122(2):211-20.
2008: Dirk Bassler; Andreas Greinacher; Chusak Okascharoen; Anne Klenner; Juliana Ditomasso; Volker Kiefel; Anthony Chan; Bosco Paes
A systematic review and survey of the management of unexpected neonatal alloimmune thrombocytopenia.
Transfusion 2008;48(1):92-8.
2007: Juliane Niessen; Gabriele Jedlitschky; Markus Grube; Sandra Bien; Ulrike Strobel; Christoph A Ritter; Andreas Greinacher; Heyo K Kroemer
Subfractionation and purification of intracellular granule-structures of human platelets: an improved method based on magnetic sorting.
Journal of immunological methods 2007;328(1-2):89-96.
2007: Andreas Greinacher
Too many hits in HIT?
American journal of hematology 2007;82(12):1035-6.
2007: Theodore E Warkentin; Andreas Greinacher
So, does low-molecular-weight heparin cause less heparin-induced thrombocytopenia than unfractionated heparin or not?
Chest 2007;132(4):1108-10.
2007: Norbert Lubenow; Peter Hinz; Axel Ekkernkamp; Andreas Greinacher
Should patients be informed about the risk of heparin-induced thrombocytopenia before prolonged low-molecular-weight heparin thromboprophylaxis post-trauma/orthopedic surgery?
European journal of haematology 2007;79(3):187-90.
2007: Kathleen Selleng; Lena E Lubenow; Andreas Greinacher; Theodore E Warkentin
Perioperative management of MYH9 hereditary macrothrombocytopenia (Fechtner syndrome).
European journal of haematology 2007;79(3):263-8.
2007: Andreas Greinacher; David Juhl; Ulrike Strobel; Antje Wessel; Norbert Lubenow; Kathleen Selleng; Petra Eichler; Theodore E Warkentin
Heparin-induced thrombocytopenia: a prospective study on the incidence, platelet-activating capacity and clinical significance of antiplatelet factor 4/heparin antibodies of the IgG, IgM, and IgA classes.
Journal of thrombosis and haemostasis : JTH 2007;5(8):1666-73.
2007: Kathleen Selleng; Theodore E Warkentin; Andreas Greinacher; Andrew M Morris; Irwin R Walker; H Alexander Heggtveit; Petra Eichler; Irene J Cybulsky
Very severe thrombocytopenia and fragmentation hemolysis mimicking thrombotic thrombocytopenic purpura associated with a giant intracardiac vegetation infected with Staphylococcus epidermidis: role of monocyte procoagulant activity induced by bacterial supernatant.
American journal of hematology 2007;82(8):766-71.
2007: Thomas Thiele; Leif Steil; Simon Gebhard; Christian Scharf; Elke Hammer; Matthias Brigulla; Norbert Lubenow; Kenneth J Clemetson; Uwe Völker; Andreas Greinacher
Profiling of alterations in platelet proteins during storage of platelet concentrates.
Transfusion 2007;47(7):1221-33.
2007: Sixten Selleng; Kathleen Selleng; S Friesecke; B Haupt; Andreas Greinacher
Mistransfusion in the emergency room.
Vox sanguinis 2007;92(4):382.
2007: Alexander Staudt; Petra Eichler; Christiane Trimpert; Stephan B Felix; Andreas Greinacher
Fc(gamma) receptors IIa on cardiomyocytes and their potential functional relevance in dilated cardiomyopathy.
Journal of the American College of Cardiology 2007;49(16):1684-92.
2007: Kathleen Selleng; Theodore E Warkentin; Andreas Greinacher
Heparin-induced thrombocytopenia in intensive care patients.
Critical care medicine 2007;35(4):1165-76.
2007: Soren Schenk; Aly El-Banayosy; Michiel Morshuis; Latif Arusoglu; Petra Eichler; Norbert Lubenow; G Tenderich; Reiner Koerfer; Andreas Greinacher; Wolfgang Prohaska
IgG classification of anti-PF4/heparin antibodies to identify patients with heparin-induced thrombocytopenia during mechanical circulatory support.
Journal of thrombosis and haemostasis : JTH 2007;5(2):235-41.
2007: Thomas Thiele; Leif Steil; Uwe Völker; Andreas Greinacher
Proteomics of blood-based therapeutics: a promising tool for quality assurance in transfusion medicine.
BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy 2007;21(3):179-93.
2006: Andreas Greinacher; Volker Kiefel; Harald Klüter; Hartmut Kroll; Bernd Pötzsch; H Riess
[Recommendations for platelet transfusion by the Joint Thrombocyte Working Party of the German Societies of Transfusion Medicine and Immunohaematology (DGTI), Thrombosis and Haemostasis Research (GTH), and Haematology and Oncology (DGHO)].
Deutsche medizinische Wochenschrift (1946) 2006;131(47):2675-9.
2006: Theodore E Warkentin; Jo-Ann I Sheppard; Christopher Sigouin; Thomas Kohlmann; Petra Eichler; Andreas Greinacher
Gender imbalance and risk factor interactions in heparin-induced thrombocytopenia.
Blood 2006;108(9):2937-41.
2006: Andreas Greinacher; Manesh Gopinadhan; Jens-Uwe Günther; Mahmoud A Omer-Adam; Ulrike Strobel; Theodore E Warkentin; Georg Papastavrou; Werner Weitschies; Christiane A Helm
Close approximation of two platelet factor 4 tetramers by charge neutralization forms the antigens recognized by HIT antibodies.
Arteriosclerosis, thrombosis, and vascular biology 2006;26(10):2386-93.
2006: Soren Schenk; Aly El-Banayosy; Wolfgang Prohaska; Latif Arusoglu; Michiel Morshuis; Wilhelm Koester-Eiserfunke; Lukasz Kizner; Edward Murray; Petra Eichler; Reiner Koerfer; Andreas Greinacher
Heparin-induced thrombocytopenia in patients receiving mechanical circulatory support.
The Journal of thoracic and cardiovascular surgery 2006;131(6):1373-81.e4.
2006: Silva Holtfreter; Katharina Roschack; Petra Eichler; Kristin Eske; Birte Holtfreter; Christian Kohler; Susanne Engelmann; Michael Hecker; Andreas Greinacher; Barbara M Broker
Staphylococcus aureus carriers neutralize superantigens by antibodies specific for their colonizing strain: a potential explanation for their improved prognosis in severe sepsis.
The Journal of infectious diseases 2006;193(9):1275-8.
2006: David Juhl; Petra Eichler; Norbert Lubenow; Ulrike Strobel; Antje Wessel; Andreas Greinacher
Incidence and clinical significance of anti-PF4/heparin antibodies of the IgG, IgM, and IgA class in 755 consecutive patient samples referred for diagnostic testing for heparin-induced thrombocytopenia.
European journal of haematology 2006;76(5):420-6.
2006: Volker Kiefel; Dirk Bassler; Hartmut Kroll; Bosco Paes; Günther Giers; Juliana Ditomasso; Heidemarie Alber; Monika Berns; Bea Wiebe; Ernst-Markus Quenzel; Jochen Hoch; Andreas Greinacher
Antigen-positive platelet transfusion in neonatal alloimmune thrombocytopenia (NAIT).
Blood 2006;107(9):3761-3.
2006: G K Lo; David Juhl; Theodore E Warkentin; Christopher Sigouin; Petra Eichler; Andreas Greinacher
Evaluation of pretest clinical score (4 T's) for the diagnosis of heparin-induced thrombocytopenia in two clinical settings.
Journal of thrombosis and haemostasis : JTH 2006;4(4):759-65.
2006: Matthias Brigulla; Thomas Thiele; Christian Scharf; Susanne Breitner-Ruddock; Simone Venz; Uwe Völker; Andreas Greinacher
Proteomics as a tool for assessment of therapeutics in transfusion medicine: evaluation of prothrombin complex concentrates.
Transfusion 2006;46(3):377-85.
2006: Andreas Greinacher
Heparin-induced thrombocytopenia: frequency and pathogenesis.
Pathophysiology of haemostasis and thrombosis 2006;35(1-2):37-45.
2006: Andreas Greinacher; Theodore E Warkentin
Recognition, treatment, and prevention of heparin-induced thrombocytopenia: review and update.
Thrombosis research 2006;118(2):165-76.
2006: Norbert Lubenow; Theodore E Warkentin; Andreas Greinacher; Antje Wessel; Debi-Ann Sloane; Erica L Krahn; Harry N Magnani
Results of a systematic evaluation of treatment outcomes for heparin-induced thrombocytopenia in patients receiving danaparoid, ancrod, and/or coumarin explain the rapid shift in clinical practice during the 1990s.
Thrombosis research 2006;117(5):507-15.
2005: Theodore E Warkentin; Richard J Cook; Victor J Marder; Jo-Ann I Sheppard; Jane C Moore; Bengt I Eriksson; Andreas Greinacher; John G Kelton
Anti-platelet factor 4/heparin antibodies in orthopedic surgery patients receiving antithrombotic prophylaxis with fondaparinux or enoxaparin.
Blood 2005;106(12):3791-6.
2005: Theodore E Warkentin; Andreas Greinacher; Sharon Craven; Lori Dewar; Jo-Ann I Sheppard; Frederick A Ofosu
Differences in the clinically effective molar concentrations of four direct thrombin inhibitors explain their variable prothrombin time prolongation.
Thrombosis and haemostasis 2005;94(5):958-64.
2005: Norbert Lubenow; Petra Eichler; Theresia Lietz; Andreas Greinacher
Lepirudin in patients with heparin-induced thrombocytopenia - results of the third prospective study (HAT-3) and a combined analysis of HAT-1, HAT-2, and HAT-3.
Journal of thrombosis and haemostasis : JTH 2005;3(11):2428-36.
2005: Andreas Greinacher; Petra Eichler; Theresia Lietz; Theodore E Warkentin
Replacement of unfractionated heparin by low-molecular-weight heparin for postorthopedic surgery antithrombotic prophylaxis lowers the overall risk of symptomatic thrombosis because of a lower frequency of heparin-induced thrombocytopenia.
Blood 2005;106(8):2921-2.
2005: Andreas Greinacher; Theodore E Warkentin
Transfusion medicine in the era of genomics and proteomics.
Transfusion medicine reviews 2005;19(4):288-94.
2005: Anja Marschner; Simon Rothenfusser; Veit Hornung; Domenik Prell; Anne Krug; Miren Kerkmann; Daniela Wellisch; Hendrik Poeck; Andreas Greinacher; Thomas Giese; Stefan Endres; Gunther Hartmann
CpG ODN enhance antigen-specific NKT cell activation via plasmacytoid dendritic cells.
European journal of immunology 2005;35(8):2347-57.
2005: Theodore E Warkentin; Andreas Greinacher
Thrombosis of the cerebral veins and sinuses.
The New England journal of medicine 2005;353(3):314-5.
2005: Andreas Greinacher; Beate Farner; Hartmut Kroll; Thomas Kohlmann; Theodore E Warkentin; Petra Eichler
Clinical features of heparin-induced thrombocytopenia including risk factors for thrombosis. A retrospective analysis of 408 patients.
Thrombosis and haemostasis 2005;94(1):132-5.
2005: Reinhold Fretschner; Klaus Dietrich; Klaus Unertl; Andreas Greinacher
Management of liver transplantation in a patient with a history of heparin-induced thrombocytopenia.
Transplant international : official journal of the European Society for Organ Transplantation 2005;18(6):664-7.
2005: Andreas Greinacher; D Janssen
[Thrombosis prophylaxis with heparins in intensive care patients].
Anästhesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS 2005;40(3):156-63.
2005: Kathleen Selleng; Sixten Selleng; Ricarda Raschke; Carsten Oliver Schmidt; Geoffrey S Rosenblood; Andreas Greinacher; Theodore E Warkentin
Immune heparin-induced thrombocytopenia can occur in patients receiving clopidogrel and aspirin.
American journal of hematology 2005;78(3):188-92.
2005: Pierre Savi; Beng H Chong; Andreas Greinacher; Yves Gruel; John G Kelton; Theodore E Warkentin; Petra Eichler; Dirk G Meuleman; Maurice Petitou; Jean-Pascal Herault; Roger Cariou; Jean-Marc Herbert
Effect of fondaparinux on platelet activation in the presence of heparin-dependent antibodies: a blinded comparative multicenter study with unfractionated heparin.
Blood 2005;105(1):139-44.
2004: Gabriele Jedlitschky; Konstanze Tirschmann; Lena E Lubenow; H Karel Nieuwenhuis; Jan-Willem N Akkerman; Andreas Greinacher; Heyo K Kroemer
The nucleotide transporter MRP4 (ABCC4) is highly expressed in human platelets and present in dense granules, indicating a role in mediator storage.
Blood 2004;104(12):3603-10.
2004: Norbert Lubenow; Petra Eichler; Theresia Lietz; Beate Farner; Andreas Greinacher
Lepirudin for prophylaxis of thrombosis in patients with acute isolated heparin-induced thrombocytopenia: an analysis of 3 prospective studies.
Blood 2004;104(10):3072-7.
2004: Theodore E Warkentin; Andreas Greinacher
Heparin-induced thrombocytopenia: recognition, treatment, and prevention: the Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy.
Chest 2004;126(3 Suppl):311S-337S.
2004: Beatrice Grossjohann; Petra Eichler; Andreas Greinacher; Sentot Santoso; Hartmut Kroll
Ceftriaxone causes drug-induced immune thrombocytopenia and hemolytic anemia: characterization of targets on platelets and red blood cells.
Transfusion 2004;44(7):1033-40.
2004: Silva Holtfreter; Kristin Bauer; Damien Thomas; Christine Feig; Vera Lorenz; Katharina Roschack; Erika Friebe; Kathleen Selleng; Sandra Lövenich; Timm Greve; Andreas Greinacher; Brigitte Panzig; Susanne Engelmann; Gérard Lina; Barbara M Bröker
egc-Encoded superantigens from Staphylococcus aureus are neutralized by human sera much less efficiently than are classical staphylococcal enterotoxins or toxic shock syndrome toxin.
Infection and immunity 2004;72(7):4061-71.
2004: Andreas Greinacher
The use of direct thrombin inhibitors in cardiovascular surgery in patients with heparin-induced thrombocytopenia.
Seminars in thrombosis and hemostasis 2004;30(3):315-27.
2004: Andreas Greinacher
Lepirudin: a bivalent direct thrombin inhibitor for anticoagulation therapy.
Expert review of cardiovascular therapy 2004;2(3):339-57.
2004: Anne F Klenner; Norbert Lubenow; Ricarda Raschke; Andreas Greinacher
Heparin-induced thrombocytopenia in children: 12 new cases and review of the literature.
Thrombosis and haemostasis 2004;91(4):719-24.
2004: Petra Eichler; Norbert Lubenow; Ulrike Strobel; Andreas Greinacher
Antibodies against lepirudin are polyspecific and recognize epitopes on bivalirudin.
Blood 2004;103(2):613-6.
2003: Theodore E Warkentin; Andreas Greinacher
Heparin-induced thrombocytopenia and cardiac surgery.
The Annals of thoracic surgery 2003;76(6):2121-31.
2003: Anne Friederike Klenner; Christoph Fusch; A Rakow; Ingrid Kadow; Elke Beyersdorff; Petra Eichler; Kathrin Wander; Theresia Lietz; Andreas Greinacher
Benefit and risk of heparin for maintaining peripheral venous catheters in neonates: a placebo-controlled trial.
The Journal of pediatrics 2003;143(6):741-5.
2003: Amos Toren; Galit Rozenfeld-Granot; Karen E Heath; Ninette Amariglio; Bianca Rocca; John Crosson; Charles J Epstein; Ferdinando Laghi; Raffaele Landolfi; Lena E Carlsson; Scott Argraves; Nicola Bizzaro; Marva Moxey-Mims; Frida Brok-Simoni; John A Martignetti; Andreas Greinacher; Gideon Rechavi
MYH9 spectrum of autosomal-dominant giant platelet syndromes: unexpected association with fibulin-1 variant-D inactivation.
American journal of hematology 2003;74(4):254-62.
2003: Andreas Greinacher; Norbert Lubenow; Petra Eichler
Anaphylactic and anaphylactoid reactions associated with lepirudin in patients with heparin-induced thrombocytopenia.
Circulation 2003;108(17):2062-5.
2003: Peter Hinz; Norbert Lubenow; Axel Ekkernkamp; Andreas Greinacher
[Informed consent on heparin-induced thrombocytopenia during thrombosis prophylaxis. A pilot study including 460 patients].
Deutsche medizinische Wochenschrift (1946) 2003;128(42):2184-8.
2003: Andreas Greinacher
Treatment options for heparin-induced thrombocytopenia.
American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 2003;60 Suppl 5():S12-8.
2003: Theodore E Warkentin; Andreas Greinacher
Heparin-induced thrombocytopenia and cardiac surgery.
The Annals of thoracic surgery 2003;76(2):638-48.
2003: Lena E Carlsson; Norbert Lubenow; Carmen Blumentritt; Reiner Kempf; Stephanie Papenberg; Winnie Schröder; Petra Eichler; Falko H Herrmann; Sentot Santoso; Andreas Greinacher
Platelet receptor and clotting factor polymorphisms as genetic risk factors for thromboembolic complications in heparin-induced thrombocytopenia.
Pharmacogenetics 2003;13(5):253-8.
2003: Andreas Greinacher; Petra Eichler; Dorothea Albrecht; Ulrike Strobel; Bernd Pötzsch; Bengt I Eriksson
Antihirudin antibodies following low-dose subcutaneous treatment with desirudin for thrombosis prophylaxis after hip-replacement surgery: incidence and clinical relevance.
Blood 2003;101(7):2617-9.
2003: Norbert Lubenow; Sixten Selleng; Hans-Georg Wollert; Petra Eichler; Bernd Müllejans; Andreas Greinacher
Heparin-induced thrombocytopenia and cardiopulmonary bypass: perioperative argatroban use.
The Annals of thoracic surgery 2003;75(2):577-9.
2003: C Sachse; M H Groschup; Rolf Warzok; Andreas Greinacher
Role of variant Creutzfeldt-Jakob disease for safety of treatment with blood components: screening of lymphatic tissue is a potential tool for risk assessment.
European journal of haematology 2003;70(1):11-6.
2002: Norbert Lubenow; Andreas Greinacher
Hirudin in heparin-induced thrombocytopenia.
Seminars in thrombosis and hemostasis 2002;28(5):431-8.
2002: Gregor Caspari; Uta Alpen; Andreas Greinacher
The risk of transfusion to the wrong patient in Germany.
Transfusion 2002;42(9):1238-9.
2002: Thomas Dittberner; Elke Schöttler; oliver ranze; Andreas Greinacher; Robert Knobler
Heparin-induced thrombocytopenia: a complication in extracorporeal photochemotherapy (photopheresis).
Journal of the American Academy of Dermatology 2002;47(3):452-3.
2002: Norbert Lubenow; Andreas Greinacher
[Hirudins in the treatment of heparin-induced thrombocytopenia and in thrombosis prophylaxis].
Hämostaseologie 2002;22(3):44-54.
2002: Norbert Lubenow; Reiner Kempf; Angelika Eichner; Petra Eichler; Lena E Carlsson; Andreas Greinacher
Heparin-induced thrombocytopenia: temporal pattern of thrombocytopenia in relation to initial use or reexposure to heparin.
Chest 2002;122(1):37-42.
2002: Lena E Carlsson; Susanne Hempel; Andreas Greinacher
Iron deficiency anaemia in young women.
European journal of haematology 2002;68(6):341-4.
2002: Andreas Greinacher
[Anticoagulation for HIT II: When should it be used therapeutically and when as prophylaxis?].
Anästhesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS 2002;37 Suppl 1():S3-7.
2002: James G White; Joan C Mattson; William L Nichols; Naomi L C Luban; Andreas Greinacher
A variant of the Sebastian platelet syndrome with unique neutrophil inclusions.
Platelets 2002;13(2):121-7.
2002: Petra Eichler; Ricarda Raschke; Norbert Lubenow; Oliver Meyer; Peter Schwind; Andreas Greinacher
The new ID-heparin/PF4 antibody test for rapid detection of heparin-induced antibodies in comparison with functional and antigenic assays.
British journal of haematology 2002;116(4):887-91.
2001: Karen E Heath; Angel Campos-Barros; Amos Toren; Galit Rozenfeld-Granot; Lena E Carlsson; J Savige; JC Denison; Martin C Gregory; J G White; David Barker; Andreas Greinacher; Charles J Epstein; Marc J Glucksman; John A Martignetti
Nonmuscle myosin heavy chain IIA mutations define a spectrum of autosomal dominant macrothrombocytopenias: May-Hegglin anomaly and Fechtner, Sebastian, Epstein, and Alport-like syndromes.
American journal of human genetics 2001;69(5):1033-45.
2001: Andreas Greinacher; Petra Eichler; Norbert Lubenow; Volker Kiefel
Drug-induced and drug-dependent immune thrombocytopenias.
Reviews in clinical and experimental hematology 2001;5(3):166-200; discussion 311-2.
2001: Peter Meisel; Lena E Carlsson; Hazem Sawaf; Jutta Fanghaenel; Andreas Greinacher; Thomas Kocher
Polymorphisms of Fc gamma-receptors RIIa, RIIIa, and RIIIb in patients with adult periodontal diseases.
Genes and immunity 2001;2(5):258-62.
2001: Beate Farner; Petra Eichler; Hartmut Kroll; Andreas Greinacher
A comparison of danaparoid and lepirudin in heparin-induced thrombocytopenia.
Thrombosis and haemostasis 2001;85(6):950-7.
2001: Andreas Greinacher; Norbert Lubenow
Recombinant hirudin in clinical practice: focus on lepirudin.
Circulation 2001;103(10):1479-84.
2001: G Weimann; Norbert Lubenow; Kathleen Selleng; Petra Eichler; D Albrecht; Andreas Greinacher
Glucosamine sulfate does not crossreact with the antibodies of patients with heparin-induced thrombocytopenia.
European journal of haematology 2001;66(3):195-9.
2001: Sixten Selleng; Norbert Lubenow; Hans-Georg Wollert; Bernd Müllejans; Andreas Greinacher
Emergency cardiopulmonary bypass in a bilaterally nephrectomized patient with a history of heparin-induced thrombocytopenia: successful reexposure to heparin.
The Annals of thoracic surgery 2001;71(3):1041-2.
2001: Norbert Lubenow; Andreas Greinacher
Drugs for the prevention and treatment of thrombosis in patients with heparin-induced thrombocytopenia.
American journal of cardiovascular drugs : drugs, devices, and other interventions 2001;1(6):429-43.
2000: Amos Toren; Galit Rozenfeld-Granot; Bianca Rocca; Charles J Epstein; Ninette Amariglio; Ferdinando Laghi; Raffaele Landolfi; Frida Brok-Simoni; Lena E Carlsson; Gideon Rechavi; Andreas Greinacher
Autosomal-dominant giant platelet syndromes: a hint of the same genetic defect as in Fechtner syndrome owing to a similar genetic linkage to chromosome 22q11-13.
Blood 2000;96(10):3447-51.
2000: Norbert Lubenow; Andreas Greinacher
Management of patients with heparin-induced thrombocytopenia: focus on recombinant hirudin.
Journal of thrombosis and thrombolysis 2000;10 Suppl 1():47-57.
2000: Norbert Lubenow; Petra Eichler; D Albrecht; Lena E Carlsson; J Kothmann; W R Rossocha; M Hahn; H Quitmann; Andreas Greinacher
Very low platelet counts in post-transfusion purpura falsely diagnosed as heparin-induced thrombocytopenia. Report of four cases and review of literature.
Thrombosis research 2000;100(3):115-25.
2000: Petra Eichler; H J Friesen; Norbert Lubenow; B Jaeger; Andreas Greinacher
Antihirudin antibodies in patients with heparin-induced thrombocytopenia treated with lepirudin: incidence, effects on aPTT, and clinical relevance.
Blood 2000;96(7):2373-8.
2000: Norbert Lubenow; Andreas Greinacher
Heparin-induced thrombocytopenia: recommendations for optimal use of recombinant hirudin.
BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy 2000;14(2):109-25.
2000: Andreas Greinacher; Petra Eichler; Norbert Lubenow; H Kwasny; M Luz
Heparin-induced thrombocytopenia with thromboembolic complications: meta-analysis of 2 prospective trials to assess the value of parenteral treatment with lepirudin and its therapeutic aPTT range.
Blood 2000;96(3):846-51.
1999: oliver ranze; P Ranze; H N Magnani; Andreas Greinacher
Heparin-induced thrombocytopenia in paediatric patients--a review of the literature and a new case treated with danaparoid sodium.
European journal of pediatrics 1999;158 Suppl 3():S130-3.
1999: Andreas Greinacher
Heparin-induced thrombocytopenia--pathogenesis and treatment.
Thrombosis and haemostasis 1999;82 Suppl 1():148-56.
1999: Andreas Greinacher; U Janssens; G Berg; M Böck; H Kwasny; Bettina Kemkes-Matthes; Petra Eichler; H Völpel; Bernd Pötzsch; M Luz
Lepirudin (recombinant hirudin) for parenteral anticoagulation in patients with heparin-induced thrombocytopenia. Heparin-Associated Thrombocytopenia Study (HAT) investigators.
Circulation 1999;100(6):587-93.
1999: Andreas Greinacher
Treatment of heparin-induced thrombocytopenia.
Thrombosis and haemostasis 1999;82(2):457-67.
1999: oliver ranze; Andreas Greinacher
[Current treatment concepts in heparin-induced thrombocytopenia].
Deutsche medizinische Wochenschrift (1946) 1999;124(28-29):865-73.
1999: Lena E Carlsson; Sentot Santoso; Carsten Spitzer; Christof Kessler; Andreas Greinacher
The alpha2 gene coding sequence T807/A873 of the platelet collagen receptor integrin alpha2beta1 might be a genetic risk factor for the development of stroke in younger patients.
Blood 1999;93(11):3583-6.
1999: Petra Eichler; U Budde; S Haas; Hartmut Kroll; Ralph M Loreth; O Meyer; U Pachmann; Bernd Pötzsch; A Schabel; D Albrecht; Andreas Greinacher
First workshop for detection of heparin-induced antibodies: validation of the heparin-induced platelet-activation test (HIPA) in comparison with a PF4/heparin ELISA.
Thrombosis and haemostasis 1999;81(4):625-9.
1999: Andreas Greinacher; H Völpel; U Janssens; Viola Hach-Wunderle; Bettina Kemkes-Matthes; Petra Eichler; H G Mueller-Velten; Bernd Pötzsch
Recombinant hirudin (lepirudin) provides safe and effective anticoagulation in patients with heparin-induced thrombocytopenia: a prospective study.
Circulation 1999;99(1):73-80.
1998: Andreas Greinacher
[Thrombosis risk in activated protein C resistance deficiency?].
Deutsche medizinische Wochenschrift (1946) 1998;123(43):1292-3.
1998: Lena E Carlsson; Sentot Santoso; G Baurichter; Hartmut Kroll; S Papenberg; Petra Eichler; N A Westerdaal; Volker Kiefel; J G van de Winkel; Andreas Greinacher
Heparin-induced thrombocytopenia: new insights into the impact of the FcgammaRIIa-R-H131 polymorphism.
Blood 1998;92(5):1526-31.
1998: Andreas Greinacher
Heparin-induced thrombocytopenia: pathophysiology and clinical concerns.
Baillière's clinical haematology 1998;11(2):461-74.
1998: I von Zabern; M Ehlers; U Grunwald; K Mauermann; Andreas Greinacher
Release of mediators of systemic inflammatory response syndrome in the course of a severe delayed hemolytic transfusion reaction caused by anti-D.
Transfusion 1998;38(5):459-68.
1998: K Olbrich; M Wiersbitzky; W Wacke; Petra Eichler; H Zinke; M Schwock; Bernhard Möx; Günter Kraatz; Wolfgang Motz; Andreas Greinacher
Atypical heparin-induced thrombocytopenia complicated by intracardiac thrombus, effectively treated with ultra-low-dose rt-PA lysis and recombinant hirudin (Lepirudin).
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 1998;9(3):273-7.
1997: Dirk Ganzer; A Gutezeit; G Mayer; Andreas Greinacher; Petra Eichler
[Prevention of thromboembolism as a cause of thromboembolic complications. A study of the incidence of heparin-induced thrombocytopenia type II].
Zeitschrift für Orthopädie und ihre Grenzgebiete 1997;135(6):543-9.
1997: Andreas Greinacher
[New antithrombotic drugs. What developments can be expected?].
Der Internist 1997;38(7):680-7.
1997: Lena E Carlsson; Andreas Greinacher; Carsten Spitzer; Reinhard Walther; Christof Kessler
Polymorphisms of the human platelet antigens HPA-1, HPA-2, HPA-3, and HPA-5 on the platelet receptors for fibrinogen (GPIIb/IIIa), von Willebrand factor (GPIb/IX), and collagen (GPIa/IIa) are not correlated with an increased risk for stroke.
Stroke; a journal of cerebral circulation 1997;28(7):1392-5.
1996: Andreas Greinacher
[Heparin-induced thrombocytopenia].
Der Internist 1996;37(11):1172-8; discussion 1178.
1996: Friedrich-Christian Riess; Bernd Pötzsch; Ralf Bader; Niels Bleese; Andreas Greinacher; C Löwer; Katharina Madlener; G Müller-Berghaus
A case report on the use of recombinant hirudin as an anticoagulant for cardiopulmonary bypass in open heart surgery.
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 1996;10(5):386-8.
1995: Andreas Greinacher; S Alban; V Dummel; Gerhard Franz; C Mueller-Eckhardt
Characterization of the structural requirements for a carbohydrate based anticoagulant with a reduced risk of inducing the immunological type of heparin-associated thrombocytopenia.
Thrombosis and haemostasis 1995;74(3):886-92.
1995: E A Martinson; S Scheible; Andreas Greinacher; P Presek
Platelet phospholipase D is activated by protein kinase C via an integrin alpha IIb beta 3-independent mechanism.
The Biochemical journal 1995;310 ( Pt 2)():623-8.
1995: Volker Kiefel; M Vicariot; Y Giovangrandi; Hartmut Kroll; M Böhringer; Andreas Greinacher; C Breitfeld; Sentot Santoso; C Mueller-Eckhardt
Alloimmunization against Iy, a low-frequency antigen on platelet glycoprotein Ib/IX as a cause of severe neonatal alloimmune thrombocytopenic purpura.
Vox sanguinis 1995;69(3):250-4.
1995: Andreas Greinacher
Antigen generation in heparin-associated thrombocytopenia: the nonimmunologic type and the immunologic type are closely linked in their pathogenesis.
Seminars in thrombosis and hemostasis 1995;21(1):106-16.
1994: U Liebenhoff; Andreas Greinacher; P Presek
The protein tyrosine kinase pp60c-src is activated upon platelet stimulation.
Cellular and molecular biology (Noisy-le-Grand, France) 1994;40(5):645-52.
1994: Andreas Greinacher; J Amiral; V Dummel; A Vissac; Volker Kiefel; C Mueller-Eckhardt
Laboratory diagnosis of heparin-associated thrombocytopenia and comparison of platelet aggregation test, heparin-induced platelet activation test, and platelet factor 4/heparin enzyme-linked immunosorbent assay.
Transfusion 1994;34(5):381-5.
1994: Andreas Greinacher; U Liebenhoff; Volker Kiefel; P Presek; C Mueller-Eckhardt
Heparin-associated thrombocytopenia: the effects of various intravenous IgG preparations on antibody mediated platelet activation--a possible new indication for high dose i.v. IgG.
Thrombosis and haemostasis 1994;71(5):641-5.
1994: Andreas Greinacher; Bernd Pötzsch; J Amiral; V Dummel; A Eichner; C Mueller-Eckhardt
Heparin-associated thrombocytopenia: isolation of the antibody and characterization of a multimolecular PF4-heparin complex as the major antigen.
Thrombosis and haemostasis 1994;71(2):247-51.
1994: Andreas Greinacher; M Möckel; C Mueller-Eckhardt
[Suppression of FcRII by intravenously administerd IgG is dependent of preparation procedures of immunoglobulins].
Beiträge zur Infusionstherapie und Transfusionsmedizin = Contributions to infusion therapy and transfusion medicine 1994;32():211-3.
1994: Andreas Greinacher; U Liebenhoff; Volker Kiefel; P Presek; C Mueller-Eckhardt
[Fc receptor-dependent platelet activation results independently of glycoprotein complex IIb/IIIa].
Beiträge zur Infusionstherapie und Transfusionsmedizin = Contributions to infusion therapy and transfusion medicine 1994;32():208-10.
1993: Andreas Greinacher; Bernd Pötzsch; Volker Kiefel; J G White; G Müller-Berghaus; C Mueller-Eckhardt
Evidence that DDAVP transiently improves hemostasis in Bernard-Soulier syndrome independent of von Willebrand-factor.
Annals of hematology 1993;67(3):149-50.
1993: Andreas Greinacher; I Michels; U Liebenhoff; P Presek; C Mueller-Eckhardt
Heparin-associated thrombocytopenia: immune complexes are attached to the platelet membrane by the negative charge of highly sulphated oligosaccharides.
British journal of haematology 1993;84(4):711-6.
1993: Andreas Greinacher; Torsten Eckhardt; J Mussmann; C Mueller-Eckhardt
Pregnancy complicated by heparin associated thrombocytopenia: management by a prospectively in vitro selected heparinoid (Org 10172).
Thrombosis research 1993;71(2):123-6.
1993: Andreas Greinacher; A Zellner; R Brangenberg; Volker Kiefel; C Mueller-Eckhardt
[Bernard-Soulier syndrome. An important differential diagnosis in chronic thrombocytopenia with bleeding complications].
Monatsschrift Kinderheilkunde : Organ der Deutschen Gesellschaft für Kinderheilkunde 1993;141(6):483-6.
1993: Andreas Greinacher; G Mueller-Eckhardt
Heparin-associated thrombocytopenia: no association of immune response with HLA.
Vox sanguinis 1993;65(2):151-3.
1993: Andreas Greinacher; K H Philippen; Bettina Kemkes-Matthes; M Möckl; C Mueller-Eckhardt; K Schaefer
Heparin-associated thrombocytopenia type II in a patient with end-stage renal disease: successful anticoagulation with the low-molecular-weight heparinoid Org 10172 during haemodialysis.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 1993;8(10):1176-7.
1992: Andreas Greinacher; Juergen Bux; V Kiefel; J G White; C Mueller-Eckhardt
May-Hegglin anomaly: a rare cause of thrombocytopenia.
European journal of pediatrics 1992;151(9):668-71.
1992: Andreas Greinacher; I Michels; M Schäfer; Volker Kiefel; C Mueller-Eckhardt
Heparin-associated thrombocytopenia in a patient treated with polysulphated chondroitin sulphate: evidence for immunological crossreactivity between heparin and polysulphated glycosaminoglycan.
British journal of haematology 1992;81(2):252-4.
1992: Andreas Greinacher; I Michels; C Mueller-Eckhardt
Heparin-associated thrombocytopenia: the antibody is not heparin specific.
Thrombosis and haemostasis 1992;67(5):545-9.
1992: Andreas Greinacher; W Drost; I Michels; J Leitl; M Gottsmann; H J Kohl; M Glaser; C Mueller-Eckhardt
Heparin-associated thrombocytopenia: successful therapy with the heparinoid Org 10172 in a patient showing cross-reaction to LMW heparins.
Annals of hematology 1992;64(1):40-2.
1992: Volker Kiefel; E Meyer; Andreas Greinacher; Hartmut Kroll; C Mueller-Eckhardt
[Neonatal isoimmune thrombocytopenia by anti-GP IIb/IIIa].
Beiträge zur Infusionstherapie = Contributions to infusion therapy 1992;30():450-3.
1992: Andreas Greinacher; I Michels; C Mueller-Eckhardt
[Heparin-associated thrombocytopenia: successful therapy of patients after prospective selection of a compatible heparinoid with the heparin-induced platelet activation test].
Beiträge zur Infusionstherapie = Contributions to infusion therapy 1992;30():408-12.
1991: Andreas Greinacher; I Michels; Volker Kiefel; C Mueller-Eckhardt
A rapid and sensitive test for diagnosing heparin-associated thrombocytopenia.
Thrombosis and haemostasis 1991;66(6):734-6.
1991: Andreas Greinacher; C Mueller-Eckhardt
[The therapy of heparin-associated thrombocytopenia].
Deutsche medizinische Wochenschrift (1946) 1991;116(39):1483-4.
1991: Andreas Greinacher; C Mueller-Eckhardt
[The diagnosis of heparin-associated thrombocytopenia].
Deutsche medizinische Wochenschrift (1946) 1991;116(39):1479-82.
1990: Andreas Greinacher; H K Nieuwenhuis; J G White
Sebastian platelet syndrome: a new variant of hereditary macrothrombocytopenia with leukocyte inclusions.
Blut 1990;61(5):282-8.
1990: Andreas Greinacher; C Mueller-Eckhardt
Hereditary types of thrombocytopenia with giant platelets and inclusion bodies in the leukocytes.
Blut 1990;60(2):53-60.
1990: Andreas Greinacher; H K Nieuwenhuis; J G White
[The Sebastian platelet syndrome. A new form of hereditary thrombocytopenia with giant thrombocytes and inclusion bodies in granulocytes].
Beiträge zur Infusionstherapie = Contributions to infusion therapy 1990;26():383-5.