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Sandro Grelli

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A Minutolo; A Brandi; Franca M Cordero; Sandro Grelli; Beatrice Macchi; F Marino-Merlo; Antonio Mastino
D(-)lentiginosine-induced apoptosis involves the intrinsic pathway and is p53-independent.
Murugan Kalimutho; Antonella Minutolo; Giorgio Federici; Sandro Grelli; Sergio Bernardini
Platinum-(IV)-derivative satraplatin induced G2/M cell cycle perturbation via p53-p21(waf1/cip1)-independent pathway in human colorectal cancer cells.
Murugan Kalimutho; Antonella Minutolo; Sandro Grelli; Amanda Formosa; Giulia Sancesario; Alessandra Valentini; Giorgio Federici; Sergio Bernardini
Satraplatin (JM-216) mediates G2/M cell cycle arrest and potentiates apoptosis via multiple death pathways in colorectal cancer cells thus overcoming platinum chemo-resistance.

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All Publications

2012: A Minutolo; A Brandi; Franca M Cordero; Sandro Grelli; Beatrice Macchi; F Marino-Merlo; Antonio Mastino
D(-)lentiginosine-induced apoptosis involves the intrinsic pathway and is p53-independent.
Cell death & disease 2012;3():e358.
2011: Murugan Kalimutho; Antonella Minutolo; Giorgio Federici; Sandro Grelli; Sergio Bernardini
Platinum-(IV)-derivative satraplatin induced G2/M cell cycle perturbation via p53-p21(waf1/cip1)-independent pathway in human colorectal cancer cells.
Acta pharmacologica Sinica 2011;32(11):1387-96.
2011: Murugan Kalimutho; Antonella Minutolo; Sandro Grelli; Amanda Formosa; Giulia Sancesario; Alessandra Valentini; Giorgio Federici; Sergio Bernardini
Satraplatin (JM-216) mediates G2/M cell cycle arrest and potentiates apoptosis via multiple death pathways in colorectal cancer cells thus overcoming platinum chemo-resistance.
Cancer chemotherapy and pharmacology 2011;67(6):1299-312.
2010: Beatrice Macchi; Antonella Minutolo; Sandro Grelli; Francesca Cardona; Franca M Cordero; Antonio Mastino; Alberto Brandi
The novel proapoptotic activity of nonnatural enantiomer of Lentiginosine.
Glycobiology 2010;20(5):500-6.
2009: Claudia Matteucci; Antonella Minutolo; Emanuela Balestrieri; Arianna Ascolani; Sandro Grelli; Beatrice Macchi; Antonio Mastino
Effector caspase activation, in the absence of a conspicuous apoptosis induction, in mononuclear cells treated with azidothymidine.
Pharmacological research : the official journal of the Italian Pharmacological Society 2009;59(2):125-33.
2008: Maria Teresa Sciortino; Maria Antonietta Medici; Francesca Marino-Merlo; Daniela Zaccaria; Maria Giuffrè-Cuculletto; Assunta Venuti; Sandro Grelli; Placido Bramanti; Antonio Mastino
Involvement of gD/HVEM interaction in NF-kB-dependent inhibition of apoptosis by HSV-1 gD.
Biochemical pharmacology 2008;76(11):1522-32.
2008: Maria Teresa Sciortino; Maria Antonietta Medici; Francesca Marino-Merlo; Daniela Zaccaria; Maria Giuffrè-Cuculletto; Assunta Venuti; Sandro Grelli; Antonio Mastino
Involvement of HVEM receptor in activation of nuclear factor kappaB by herpes simplex virus 1 glycoprotein D.
Cellular microbiology 2008;10(11):2297-311.
2007: Emanuela Balestrieri; Sandro Grelli; Claudia Matteucci; Antonella Minutolo; Gabriella d'Ettorre; Fiorella Di Sora; Francesco Montella; Vincenzo Vullo; STEFANO VELLA; Cartesio Favalli; Beatrice Macchi; Antonio Mastino
Apoptosis-associated gene expression in HIV-infected patients in response to successful antiretroviral therapy.
Journal of medical virology 2007;79(2):111-7.
2007: M Teresa Sciortino; Maria Antonietta Medici; Francesca Marino-Merlo; Daniela Zaccaria; Maria Giuffrè; Assunta Venuti; Sandro Grelli; Antonio Mastino
Signaling pathway used by HSV-1 to induce NF-kappaB activation: possible role of herpes virus entry receptor A.
Annals of the New York Academy of Sciences 2007;1096():89-96.
2006: Maria Teresa Sciortino; Donata Perri; Maria Antonietta Medici; Sandro Grelli; Annalucia Serafino; Christoph Borner; Antonio Mastino
Role of Bcl-2 expression for productive herpes simplex virus 2 replication.
Virology 2006;356(1-2):136-46.
2006: Sandro Grelli; Emanuela Balestrieri; Claudia Matteucci; Antonella Minutolo; Gabriella d'Ettorre; Filippo Lauria; Francesco Montella; Vincenzo Vullo; STEFANO VELLA; Cartesio Favalli; Antonio Mastino; Beatrice Macchi
Apoptotic cell signaling in lymphocytes from HIV+ patients during successful therapy.
Annals of the New York Academy of Sciences 2006;1090():130-7.
2005: Ruggiero Mango; Silvia Biocca; Francesca del Vecchio; Fabrizio Clementi; Federica Sangiuolo; Francesca Amati; Antonio Filareto; Sandro Grelli; Paola Spitalieri; Ilaria Filesi; Cartesio Favalli; Renato Lauro; Jawahar L Mehta; Francesco Romeo; Giuseppe Novelli
In vivo and in vitro studies support that a new splicing isoform of OLR1 gene is protective against acute myocardial infarction.
Circulation research 2005;97(2):152-8.
2005: Cartesio D'Agostini; Francesca Pica; Giuseppe Febbraro; Sandro Grelli; Carlo Chiavaroli; Enrico Garaci
Antitumour effect of OM-174 and cyclophosphamide on murine B16 melanoma in different experimental conditions.
International immunopharmacology 2005;5(7-8):1205-12.
2004: Santina Tacconi; Roberta Perri; Emanuela Balestrieri; Sandro Grelli; Sergio Bernardini; Roberta Annichiarico; Antonio Mastino; Carlo Caltagirone; Beatrice Macchi
Increased caspase activation in peripheral blood mononuclear cells of patients with Alzheimer's disease.
Experimental neurology 2004;190(1):254-62.
2004: Sandro Grelli; Gabriella d'Ettorre; Filippo Lauria; Francesco Montella; Loide Di Traglia; Miriam Lichtner; Vincenzo Vullo; Cartesio Favalli; STEFANO VELLA; Beatrice Macchi; Antonio Mastino
Inverse correlation between CD8+ lymphocyte apoptosis and CD4+ cell counts during potent antiretroviral therapy in HIV patients.
The Journal of antimicrobial chemotherapy 2004;53(3):494-500.
2003: Sandro Grelli; Gabriella D'Ettore; Filippo Lauria; Francesco Montella; Loide Di Traglia; Cartesio D'Agostini; Miriam Lichtner; Vincenzo Vullo; Cartesio Favalli; STEFANO VELLA; Beatrice Macchi; Antonio Mastino
CD4+ lymphocyte increases in HIV patients during potent antiretroviral therapy are dependent on inhibition of CD8+ cell apoptosis.
Annals of the New York Academy of Sciences 2003;1010():560-4.
2003: Antonio Mastino; Cartesio Favalli; A R Camilli; C Malerba; Sandro Grelli; A Calugi
Umbilical cord blood: the role of apoptosis in the control of CD34+ cell counts.
Placenta 2003;24(1):113-5.
2001: J Zhang; Emanuela Balestrieri; Sandro Grelli; Claudia Matteucci; V Pagnini; Cartesio D'Agostini; Antonio Mastino; Beatrice Macchi
Efficacy of 3'-azido 3'deoxythymidine (AZT) in preventing HTLV-1 transmission to human cord blood mononuclear cells.
Virus research 2001;78(1-2):67-78.
2001: Sandro Grelli; Loide Di Traglia; Claudia Matteucci; Miriam Lichtner; Vincenzo Vullo; Fiorella Di Sora; Filippo Lauria; Francesco Montella; Cartesio Favalli; STEFANO VELLA; Beatrice Macchi; Antonio Mastino
Changes in apoptosis after interruption of potent antiretroviral therapy in patients with maximal HIV-1-RNA suppression.
AIDS (London, England) 2001;15(9):1178-81.
2000: Sandro Grelli; S Campagna; Miriam Lichtner; G Ricci; STEFANO VELLA; Vincenzo Vullo; Francesco Montella; S Di Fabio; Cartesio Favalli; Antonio Mastino; Beatrice Macchi
Spontaneous and anti-Fas-induced apoptosis in lymphocytes from HIV-infected patients undergoing highly active anti-retroviral therapy.
AIDS (London, England) 2000;14(8):939-49.
2000: Alberto Galante; Antonio Pietroiusti; S Carta; L Franceschelli; Paola Piccolo; Antonio Mastino; Carla Fontana; Sandro Grelli; Antonio Bergamaschi; Andrea Magrini; Cartesio Favalli
Infection with Helicobacter pylori and leukocyte response in patients with myocardial infarction.
European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 2000;19(4):298-300.
2000: Cesidio Giuliani; Giorgio Napolitano; Antonio Mastino; S Di Vincenzo; Cartesio D'Agostini; Sandro Grelli; Ines Bucci; dinah singer; Leonard D Kohn; Fabrizio Monaco; Enrico Garaci; Cartesio Favalli
Thymosin-alpha1 regulates MHC class I expression in FRTL-5 cells at transcriptional level.
European journal of immunology 2000;30(3):778-86.
1999: Claudia Matteucci; Sandro Grelli; enrico de smaele; Carla Fontana; Antonio Mastino
Identification of nuclei from apoptotic, necrotic, and viable lymphoid cells by using multiparameter flow cytometry.
Cytometry 1999;35(2):145-53.
1998: Beatrice Macchi; Sandro Grelli; Claudia Matteucci; Mario Milco D'Elios; M De Carli; Cartesio Favalli; Gianfranco Del Prete; Antonio Mastino
Human Th1 and Th2 T-cell clones are equally susceptible to infection and immortalization by human T-lymphotropic virus type I.
The Journal of general virology 1998;79 ( Pt 10)():2469-74.
1997: Antonio Mastino; Maria Teresa Sciortino; Maria Antonietta Medici; Donata Perri; M G Ammendolia; Sandro Grelli; C Amici; A Pernice; S Guglielmino
Herpes simplex virus 2 causes apoptotic infection in monocytoid cells.
Cell death and differentiation 1997;4(7):629-38.
1997: Antonio Mastino; Sandro Grelli; Cartesio Favalli; Claudia Matteucci; M De Carli; E Garaci; Beatrice Macchi
Interleukin 4 stimulates infection and temporary growth of human neonatal lymphocytes exposed in vitro to human T-lymphotropic virus type I, but fails to substitute for interleukin 2 in the immortalization of infected cultures.
The Journal of general virology 1997;78 ( Pt 10)():2565-74.
1997: Alberto Galante; Antonio Pietroiusti; Andrea Magrini; S Carta; L Franceschelli; Paola Piccolo; Giuseppe Raimondo Pistolese; E Martelli; Antonio Mastino; Claudia Matteucci; Sandro Grelli; Cartesio Favalli
Leucocyte rheological properties are altered in patients with diffuse atherosclerosis.
Thrombosis and haemostasis 1997;77(6):1073-6.
1997: Beatrice Macchi; Isabella Faraoni; J Zhang; Sandro Grelli; Cartesio Favalli; Antonio Mastino; Enzo Bonmassar
AZT inhibits the transmission of human T cell leukaemia/lymphoma virus type I to adult peripheral blood mononuclear cells in vitro.
The Journal of general virology 1997;78 ( Pt 5)():1007-16.
1995: Adriano Venditti; M T Scimò; Giovanni Del Poeta; Francesco Buccisano; Roberto Stasi; Antonio Mastino; Sandro Grelli; Cartesio Favalli; Enrico Garaci; G Papa
Recombinant interferon alpha 2a, thymopentin and low doses of cytosine arabinoside for the treatment of myelodysplastic syndromes: a pilot study.
Leukemia & lymphoma 1995;16(3-4):335-42.
1994: Enrico Garaci; G Rocchi; L Perroni; C D'Agostini; F Soscia; Sandro Grelli; Antonio Mastino; Cartesio Favalli
Combination treatment with zidovudine, thymosin alpha 1 and interferon-alpha in human immunodeficiency virus infection.
International journal of clinical & laboratory research 1994;24(1):23-8.
1993: Antonio Mastino; Sandro Grelli; Mauro Piacentini; Serafina Oliverio; Cartesio Favalli; C F Perno; E Garci
Correlation between induction of lymphocyte apoptosis and prostaglandin E2 production by macrophages infected with HIV.
Cellular immunology 1993;152(1):120-30.
1992: Antonio Mastino; Cartesio Favalli; Sandro Grelli; Guido Rasi; Francesca Pica; A L Goldstein; Enrico Garaci
Combination therapy with thymosin alpha 1 potentiates the anti-tumor activity of interleukin-2 with cyclophosphamide in the treatment of the Lewis lung carcinoma in mice.
International journal of cancer. Journal international du cancer 1992;50(3):493-9.
1992: Antonio Mastino; Mauro Piacentini; Sandro Grelli; Cartesio Favalli; Francesco Autuori; L Tentori; Serafina Oliverio; Enrico Garaci
Induction of apoptosis in thymocytes by prostaglandin E2 in vivo.
Developmental immunology 1992;2(4):263-71.
1991: Antonio Mastino; Sandro Grelli; M G Premrov; Cartesio Favalli
Susceptibility to influenza A virus infection in mice immunosuppressed with cyclophosphamide.
Journal of chemotherapy (Florence, Italy) 1991;3(3):156-61.
1991: Antonio Mastino; Cartesio Favalli; Sandro Grelli; F Innocenti; Enrico Garaci
Thymosin alpha 1 potentiates interleukin 2-induced cytotoxic activity in mice.
Cellular immunology 1991;133(1):196-205.
1991: Antonio Mastino; Cartesio Favalli; Sandro Grelli; Enrico Garaci
Interaction between thymic hormones and other immunomodulatory agents.
Annali dell'Istituto superiore di sanità 1991;27(1):51-6.
1991: Antonio Mastino; Sandro Grelli; Cartesio Favalli; Enrico Garaci
Effect of di-M-PGE2 on T cell differentiation. Flow cytometry study at thymus level.
Advances in prostaglandin, thromboxane, and leukotriene research 1991;21B():851-4.
1989: Francesca Pica; Antonio Mastino; Sandro Grelli; T Jezzi; Cartesio Favalli
Combined treatment with thymosin alpha 1 and interferon enhances NK activity in immunosuppressed tumor bearing mice.
Journal of chemotherapy (Florence, Italy) 1989;1(4 Suppl):1167-9.
1989: Antonio Mastino; Cartesio Favalli; M L Moras; Sandro Grelli; Enzo Bonmassar
Flow cytometric method for the evaluation of the biological activity of thymic hormones.
Journal of chemotherapy (Florence, Italy) 1989;1(4 Suppl):459-60.
1989: Antonio Mastino; Cartesio Favalli; T Jezzi; Sandro Grelli; Francesca Pica; Enrico Garaci
Modifications in spleen lymphocyte subsets after cyclophosphamide and 16,16-dimethyl prostaglandin E2 administration in mice.
Journal of chemotherapy (Florence, Italy) 1989;1(4 Suppl):454-6.
1989: Cartesio Favalli; Antonio Mastino; T Jezzi; Sandro Grelli; A L Goldstein; Enrico Garaci
Synergistic effect of thymosin alpha 1 and alpha beta-interferon on NK activity in tumor-bearing mice.
International journal of immunopharmacology 1989;11(5):443-50.
1987: Cartesio Favalli; Antonio Mastino; Sandro Grelli; Enrico Garaci
Correlation between the effects of prostaglandins and interferon on B-16 melanoma growth and their modulation on natural killer activity.
Advances in prostaglandin, thromboxane, and leukotriene research 1987;17A():159-62.