FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Howard Grey

Research Profile

Living Beings

Genes & Molecular Sequences

Amino Acid Sequences

Concepts & Ideas

Molecular Sequence Data

Chemicals & Drugs

Anatomy

Physiology

Lymphocyte Activation

Phenomena

Protein Binding

Co-author Network

Publications

TOP 3
Cecilia S Lindestam Arlehamn; Denise M McKinney; Federico Mele; Bjoern Peters; Federica Sallusto; Anna Gerasimova; Jason A Greenbaum; Howard Grey; Ryan Henderson; Eddie A James; Yohan Kim; William W Kwok; John Sidney; Justine Swann; Randy Taplitz; Alessandro Sette
Memory T cells in latent Mycobacterium tuberculosis infection are directed against three antigenic islands and largely contained in a CXCR3+CCR6+ Th1 subset.
Carla Oseroff; Bjoern Peters; Federica Sallusto; Rafeul Alam; Tess M Brodie; David H Broide; Jason A Greenbaum; Howard Grey; Ravi Kolla; Denise M McKinney; John Sidney; Scott Southwood; Victoria Tripple; Randi Vita; Alessandro Sette
T cell responses to known allergen proteins are differently polarized and account for a variable fraction of total response to allergen extracts.
Carla Oseroff; Bjoern Peters; Anna Pomés; David H Broide; Jason Greenbaum; Howard Grey; Ravi Kolla; John Sidney; Victoria Tripple; Robert A Wood; Alessandro Sette
Analysis of T cell responses to the major allergens from German cockroach: epitope specificity and relationship to IgE production.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Howard Grey (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2013: Cecilia S Lindestam Arlehamn; Denise M McKinney; Federico Mele; Bjoern Peters; Federica Sallusto; Anna Gerasimova; Jason A Greenbaum; Howard Grey; Ryan Henderson; Eddie A James; Yohan Kim; William W Kwok; John Sidney; Justine Swann; Randy Taplitz; Alessandro Sette
Memory T cells in latent Mycobacterium tuberculosis infection are directed against three antigenic islands and largely contained in a CXCR3+CCR6+ Th1 subset.
PLoS pathogens 2013;9(1):e1003130.
2012: Carla Oseroff; Bjoern Peters; Federica Sallusto; Rafeul Alam; Tess M Brodie; David H Broide; Jason A Greenbaum; Howard Grey; Ravi Kolla; Denise M McKinney; John Sidney; Scott Southwood; Victoria Tripple; Randi Vita; Alessandro Sette
T cell responses to known allergen proteins are differently polarized and account for a variable fraction of total response to allergen extracts.
Journal of immunology (Baltimore, Md. : 1950) 2012;189(4):1800-11.
2012: Carla Oseroff; Bjoern Peters; Anna Pomés; David H Broide; Jason Greenbaum; Howard Grey; Ravi Kolla; John Sidney; Victoria Tripple; Robert A Wood; Alessandro Sette
Analysis of T cell responses to the major allergens from German cockroach: epitope specificity and relationship to IgE production.
Journal of immunology (Baltimore, Md. : 1950) 2012;189(2):679-88.
2012: Cecilia S Lindestam Arlehamn; John Sidney; Randy Taplitz; Rhea N Coler; Jason A Greenbaum; Howard Grey; Ryan Henderson; Eddie A James; William W Kwok; Denise M McKinney; Magdalini Moutaftsi; Daniel Park; Bjoern Peters; Alessandro Sette
Dissecting mechanisms of immunodominance to the common tuberculosis antigens ESAT-6, CFP10, Rv2031c (hspX), Rv2654c (TB7.7), and Rv1038c (EsxJ).
Journal of immunology (Baltimore, Md. : 1950) 2012;188(10):5020-31.
2011: Daniela Weiskopf; Lauren E Yauch; Sujan Shresta; John Sidney; Michael A Angelo; Aruna D De Silva; Aravinda M de Silva; Jason A Greenbaum; Howard Grey; Daisy V John; Ravi V Kolla; Bjoern Peters; Alessandro Sette
Insights into HLA-restricted T cell responses in a novel mouse model of dengue virus infection point toward new implications for vaccine design.
Journal of immunology (Baltimore, Md. : 1950) 2011;187(8):4268-79.
2010: Carla Oseroff; John Sidney; Maya F Kotturi; Ravi Kolla; Rafeul Alam; David H Broide; Stephen I Wasserman; Daniela Weiskopf; Denise M McKinney; Jo L Chung; Arnd Petersen; Howard Grey; Bjoern Peters; Alessandro Sette
Molecular determinants of T cell epitope recognition to the common Timothy grass allergen.
Journal of immunology (Baltimore, Md. : 1950) 2010;185(2):943-55.
2010: Kerrie Vaughan; Jason Greenbaum; Yohan Kim; Randi Vita; Jo Chung; Bjoern Peters; David Broide; Richard Goodman; Howard Grey; Alessandro Sette
Towards defining molecular determinants recognized by adaptive immunity in allergic disease: an inventory of the available data.
Journal of allergy 2010;2010():628026.
2010: Maya F Kotturi; Jason Botten; Matt Maybeno; John Sidney; Jean Glenn; Huynh-Hoa Bui; Carla Oseroff; Shane Crotty; Bjoern Peters; Howard Grey; Daniel M Altmann; Michael J Buchmeier; Alessandro Sette
Polyfunctional CD4+ T cell responses to a set of pathogenic arenaviruses provide broad population coverage.
Immunome research 2010;6():4.
2009: Alessandro Sette; Howard Grey; Carla Oseroff; Bjoern Peters; Magdalini Moutaftsi; Shane Crotty; Erika Assarsson; Jay Greenbaum; Yohan Kim; Ravi Kolla; David Tscharke; David Koelle; R Paul Johnson; Janice Blum; Steven Head; John Sidney
Definition of epitopes and antigens recognized by vaccinia specific immune responses: their conservation in variola virus sequences, and use as a model system to study complex pathogens.
Vaccine 2009;27 Suppl 6():G21-6.
2009: Maya F Kotturi; Jason Botten; John Sidney; Huynh-Hoa Bui; Lori Giancola; Matt Maybeno; Josie Babin; Carla Oseroff; Valerie Pasquetto; Jason A Greenbaum; Bjoern Peters; Joey Ting; Danh Do; Lo Vang; Jeff Alexander; Howard Grey; Michael J Buchmeier; Alessandro Sette
A multivalent and cross-protective vaccine strategy against arenaviruses associated with human disease.
PLoS pathogens 2009;5(12):e1000695.
2009: Magdalini Moutaftsi; Shahram Salek-Ardakani; Michael Croft; Bjoern Peters; John Sidney; Howard Grey; Alessandro Sette
Correlates of protection efficacy induced by vaccinia virus-specific CD8+ T-cell epitopes in the murine intranasal challenge model.
European journal of immunology 2009;39(3):717-22.
2009: Maya F Kotturi; Erika Assarsson; Bjoern Peters; Howard Grey; Carla Oseroff; Valerie Pasquetto; Alessandro Sette
Of mice and humans: how good are HLA transgenic mice as a model of human immune responses?
Immunome research 2009;5():3.
2008: Erika Assarsson; Huynh-Hoa Bui; John Sidney; Qing Zhang; Jean Glenn; Carla Oseroff; Innocent N Mbawuike; Jeff Alexander; Mark J Newman; Howard Grey; Alessandro Sette
Immunomic analysis of the repertoire of T-cell specificities for influenza A virus in humans.
Journal of virology 2008;82(24):12241-51.
2008: Maya F Kotturi; Iain Scott; Tom Wolfe; Bjoern Peters; John Sidney; Hilde Cheroutre; Matthias G von Herrath; Michael J Buchmeier; Howard Grey; Alessandro Sette
Naive precursor frequencies and MHC binding rather than the degree of epitope diversity shape CD8+ T cell immunodominance.
Journal of immunology (Baltimore, Md. : 1950) 2008;181(3):2124-33.
2008: Alessandro Sette; Magdalini Moutaftsi; Juan Moyron-Quiroz; Megan M McCausland; D Huw Davies; Robert J Johnston; Bjoern Peters; Mohammed Rafii-El-Idrissi Benhnia; Julia Hoffmann; Hua-Poo Su; Kavita Singh; David N Garboczi; Steven Head; Howard Grey; Philip L Felgner; Shane Crotty
Selective CD4+ T cell help for antibody responses to a large viral pathogen: deterministic linkage of specificities.
Immunity 2008;28(6):847-58.
2008: Carla Oseroff; Bjoern Peters; Valerie Pasquetto; Magdalini Moutaftsi; John Sidney; Vijay Panchanathan; David C Tscharke; Bernard Maillere; Howard Grey; Alessandro Sette
Dissociation between epitope hierarchy and immunoprevalence in CD8 responses to vaccinia virus western reserve.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(11):7193-202.
2008: Erika Assarsson; Jason A Greenbaum; Magnus Sundström; Lana Schaffer; Jennifer A Hammond; Valerie Pasquetto; Carla Oseroff; R Curtis Hendrickson; Elliot J Lefkowitz; David C Tscharke; John Sidney; Howard Grey; Steven R Head; Bjoern Peters; Alessandro Sette
Kinetic analysis of a complete poxvirus transcriptome reveals an immediate-early class of genes.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(6):2140-5.
2008: Laura Zarebski; Kerrie Vaughan; John Sidney; Bjoern Peters; Howard Grey; Kim D Janda; Arturo Casadevall; Alessandro Sette
Analysis of epitope information related to Bacillus anthracis and Clostridium botulinum.
Expert review of vaccines 2008;7(1):55-74.
2007: Erika Assarsson; John Sidney; Carla Oseroff; Valerie Pasquetto; Huynh-Hoa Bui; Nicole Frahm; Christian Brander; Bjoern Peters; Howard Grey; Alessandro Sette
A quantitative analysis of the variables affecting the repertoire of T cell specificities recognized after vaccinia virus infection.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(12):7890-901.
2007: Magdalini Moutaftsi; Huynh-Hoa Bui; Bjoern Peters; John Sidney; Shahram Salek-Ardakani; Carla Oseroff; Valerie Pasquetto; Shane Crotty; Michael Croft; Elliot J Lefkowitz; Howard Grey; Alessandro Sette
Vaccinia virus-specific CD4+ T cell responses target a set of antigens largely distinct from those targeted by CD8+ T cell responses.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(11):6814-20.
2007: Maya F Kotturi; Bjoern Peters; Fernando Buendia-Laysa; John Sidney; Carla Oseroff; Jason Botten; Howard Grey; Michael J Buchmeier; Alessandro Sette
The CD8+ T-cell response to lymphocytic choriomeningitis virus involves the L antigen: uncovering new tricks for an old virus.
Journal of virology 2007;81(10):4928-40.
2006: Magdalini Moutaftsi; Bjoern Peters; Valerie Pasquetto; David C Tscharke; John Sidney; Huynh-Hoa Bui; Howard Grey; Alessandro Sette
A consensus epitope prediction approach identifies the breadth of murine T(CD8+)-cell responses to vaccinia virus.
Nature biotechnology 2006;24(7):817-9.
2006: Randi Vita; Kerrie Vaughan; Laura Zarebski; Nima Salimi; Ward Fleri; Howard Grey; Muthuraman Sathiamurthy; John Mokili; Huynh-Hoa Bui; Philip Bourne; Julia V Ponomarenko; romulo de castro; Russell K Chan; John Sidney; Stephen S Wilson; Scott Douglas Stewart; Scott Way; Bjoern Peters; Alessandro Sette
Curation of complex, context-dependent immunological data.
BMC bioinformatics 2006;7():341.
2005: Valerie Pasquetto; Huynh-Hoa Bui; Rielle Giannino; Cindy Banh; Mirza Fareed; John Sidney; Carla Oseroff; David C Tscharke; Kari Irvine; Jack R Bennink; Bjoern Peters; Scott Southwood; Vincenzo Cerundolo; Howard Grey; jon yewdell; Alessandro Sette
HLA-A*0201, HLA-A*1101, and HLA-B*0702 transgenic mice recognize numerous poxvirus determinants from a wide variety of viral gene products.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(8):5504-15.
2005: Carla Oseroff; FERDYNAND KOS; Huynh-Hoa Bui; Bjoern Peters; Valerie Pasquetto; Jean Glenn; Tara Palmore; John Sidney; David C Tscharke; Jack R Bennink; Scott Southwood; Howard Grey; jon yewdell; Alessandro Sette
HLA class I-restricted responses to vaccinia recognize a broad array of proteins mainly involved in virulence and viral gene regulation.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(39):13980-5.
2004: Katsuji Sugie; Myung-Shin Jeon; Howard Grey
Activation of naïve CD4 T cells by anti-CD3 reveals an important role for Fyn in Lck-mediated signaling.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(41):14859-64.
2003: Kazuhiko Kimachi; Katsuji Sugie; Howard Grey
Effector T cells have a lower ligand affinity threshold for activation than naive T cells.
International immunology 2003;15(7):885-92.
2003: Wen Yang; Howard Grey
Study of the mechanism of TCR antagonism using dual-TCR-expressing T cells.
Journal of immunology (Baltimore, Md. : 1950) 2003;170(9):4532-8.
2002: Alain Luxembourg; Howard Grey
Strong induction of tyrosine phosphorylation, intracellular calcium, nuclear transcription factors and interferongamma, but weak induction of IL-2 in naïve T cells stimulated by bacterial superantigen.
Cellular immunology 2002;219(1):28-37.
2002: Jianyong Huang; Pei-Fen Lo; Tomasz Zal; Nicholas R J Gascoigne; Brian A Smith; Steven D Levin; Howard Grey
CD28 plays a critical role in the segregation of PKC theta within the immunologic synapse.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(14):9369-73.
2002: Rongfang Wang; Yiran Wang-Zhu; Howard Grey
Interactions between double positive thymocytes and high affinity ligands presented by cortical epithelial cells generate double negative thymocytes with T cell regulatory activity.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(4):2181-6.
2002: David A Ostrov; Matthew M Roden; Wuxian Shi; Edith Palmieri; Gregory J Christianson; Lisa Mendoza; Gilbert Villaflor; Darcie Tilley; Nilabh Shastri; Howard Grey; Steven C Almo; Derry C Roopenian; Stanley G Nathenson
How H13 histocompatibility peptides differing by a single methyl group and lacking conventional MHC binding anchor motifs determine self-nonself discrimination.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(1):283-9.
2000: J Huang; D Tilly; A Altman; Katsuji Sugie; Howard Grey
T-cell receptor antagonists induce Vav phosphorylation by selective activation of Fyn kinase.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(20):10923-9.
2000: A Franco; D A Tilly; I Gramaglia; Michael Croft; L Cipolla; Morten Meldal; Howard Grey
Epitope affinity for MHC class I determines helper requirement for CTL priming.
Nature immunology 2000;1(2):145-50.
2000: Maaike E Ressing; WJ van Driel; RM Brandt; Gemma G Kenter; J Hans De Jong; T Bauknecht; Gert Jan Fleuren; P Hoogerhout; Rienk Offringa; A Sette; E Celis; Howard Grey; Baptist J Trimbos; W Martin Kast; Cornelis J M Melief
Detection of T helper responses, but not of human papillomavirus-specific cytotoxic T lymphocyte responses, after peptide vaccination of patients with cervical carcinoma.
Journal of immunotherapy (Hagerstown, Md. : 1997) 2000;23(2):255-66.
2000: J Huang; Katsuji Sugie; D M La Face; A Altman; Howard Grey
TCR antagonist peptides induce formation of APC-T cell conjugates and activate a Rac signaling pathway.
European journal of immunology 2000;30(1):50-8.
1999: Rongfang Wang; Y Wang-Zhu; C R Gabaglia; Kazuhiko Kimachi; Howard Grey
The stimulation of low-affinity, nontolerized clones by heteroclitic antigen analogues causes the breaking of tolerance established to an immunodominant T cell epitope.
The Journal of experimental medicine 1999;190(7):983-94.
1999: Katsuji Sugie; Takafumi Tomura; K Takakura; T Kawano; M Taniguchi; Howard Grey; KIMISHIGE ISHIZAKA
Target cells for an immunosuppressive cytokine, glycosylation-inhibiting factor.
International immunology 1999;11(7):1149-56.
1999: A Franco; T Yokoyama; D Huynh; C Thomson; Stanley G Nathenson; Howard Grey
Fine specificity and MHC restriction of trinitrophenyl-specific CTL.
Journal of immunology (Baltimore, Md. : 1950) 1999;162(6):3388-94.
1998: U Zügel; Rongfang Wang; G Shih; Alessandro Sette; Jeff Alexander; Howard Grey
Termination of peripheral tolerance to a T cell epitope by heteroclitic antigen analogues.
Journal of immunology (Baltimore, Md. : 1950) 1998;161(4):1705-9.
1998: Carla Oseroff; Alessandro Sette; PA Wentworth; E Celis; Ajesh Maewal; Carol Dahlberg; John Fikes; RT Kubo; Robert W Chesnut; Howard Grey; Jeff Alexander
Pools of lipidated HTL-CTL constructs prime for multiple HBV and HCV CTL epitope responses.
Vaccine 1998;16(8):823-33.
1998: Paul R Rogers; Howard Grey; Michael Croft
Modulation of naive CD4 T cell activation with altered peptide ligands: the nature of the peptide and presentation in the context of costimulation are critical for a sustained response.
Journal of immunology (Baltimore, Md. : 1950) 1998;160(8):3698-704.
1998: Scott Southwood; John Sidney; A Kondo; Marie-France del Guercio; Ettore Appella; S Hoffman; RT Kubo; Robert W Chesnut; Howard Grey; Alessandro Sette
Several common HLA-DR types share largely overlapping peptide binding repertoires.
Journal of immunology (Baltimore, Md. : 1950) 1998;160(7):3363-73.
1998: Rongfang Wang; A Nelson; Kazuhiko Kimachi; Howard Grey; A G Farr
The role of peptides in thymic positive selection of class II major histocompatibility complex-restricted T cells.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(7):3804-9.
1997: Kazuhiko Kimachi; Michael Croft; Howard Grey
The minimal number of antigen-major histocompatibility complex class II complexes required for activation of naive and primed T cells.
European journal of immunology 1997;27(12):3310-7.
1997: Jeff Alexander; Carla Oseroff; John Sidney; PA Wentworth; E Keogh; G Hermanson; Francis V Chisari; RT Kubo; Howard Grey; Alessandro Sette
Derivation of HLA-A11/Kb transgenic mice: functional CTL repertoire and recognition of human A11-restricted CTL epitopes.
Journal of immunology (Baltimore, Md. : 1950) 1997;159(10):4753-61.
1997: Brian D Livingston; Claire Crimi; Howard Grey; Glenn Ishioka; Francis V Chisari; John Fikes; H Grey; Robert W Chesnut; Alessandro Sette
The hepatitis B virus-specific CTL responses induced in humans by lipopeptide vaccination are comparable to those elicited by acute viral infection.
Journal of immunology (Baltimore, Md. : 1950) 1997;159(3):1383-92.
1997: Marie-France del Guercio; Jeff Alexander; RT Kubo; T Arrhenius; Ajesh Maewal; Ettore Appella; Stephen L Hoffman; T Jones; D Valmori; K Sakaguchi; Howard Grey; Alessandro Sette
Potent immunogenic short linear peptide constructs composed of B cell epitopes and Pan DR T helper epitopes (PADRE) for antibody responses in vivo.
Vaccine 1997;15(4):441-8.
1997: Antonella Vitiello; A Sette; L Yuan; P Farness; Scott Southwood; John Sidney; Robert W Chesnut; Howard Grey; Brian D Livingston
Comparison of cytotoxic T lymphocyte responses induced by peptide or DNA immunization: implications on immunogenicity and immunodominance.
European journal of immunology 1997;27(3):671-8.
1997: D M La Face; C Couture; K Anderson; G Shih; J Alexander; A Sette; T Mustelin; A Altman; Howard Grey
Differential T cell signaling induced by antagonist peptide-MHC complexes and the associated phenotypic responses.
Journal of immunology (Baltimore, Md. : 1950) 1997;158(5):2057-64.
1997: A Kondo; John Sidney; Scott Southwood; Marie-France del Guercio; Ettore Appella; H Sakamoto; Howard Grey; E Celis; Robert W Chesnut; RT Kubo; Alessandro Sette
Two distinct HLA-A*0101-specific submotifs illustrate alternative peptide binding modes.
Immunogenetics 1997;45(4):249-58.
1996: John Sidney; Scott Southwood; Marie-France del Guercio; Howard Grey; Robert W Chesnut; RT Kubo; Alessandro Sette
Specificity and degeneracy in peptide binding to HLA-B7-like class I molecules.
Journal of immunology (Baltimore, Md. : 1950) 1996;157(8):3480-90.
1996: PA Wentworth; Alessandro Sette; E Celis; John Sidney; Scott Southwood; Claire Crimi; S Stitely; Elissa Keogh; N C Wong; Brian D Livingston; D Alazard; Antonella Vitiello; Howard Grey; Francis V Chisari; Robert W Chesnut; John Fikes
Identification of A2-restricted hepatitis C virus-specific cytotoxic T lymphocyte epitopes from conserved regions of the viral genome.
International immunology 1996;8(5):651-9.
1996: John Sidney; Howard Grey; Scott Southwood; E Celis; PA Wentworth; Marie-France del Guercio; RT Kubo; Robert W Chesnut; Alessandro Sette
Definition of an HLA-A3-like supermotif demonstrates the overlapping peptide-binding repertoires of common HLA molecules.
Human immunology 1996;45(2):79-93.
1996: PA Wentworth; Antonella Vitiello; John Sidney; Elissa Keogh; Robert W Chesnut; Howard Grey; Alessandro Sette
Differences and similarities in the A2.1-restricted cytotoxic T cell repertoire in humans and human leukocyte antigen-transgenic mice.
European journal of immunology 1996;26(1):97-101.
1995: A Kondo; John Sidney; Scott Southwood; Marie-France del Guercio; Ettore Appella; H Sakamoto; E Celis; Howard Grey; Robert W Chesnut; RT Kubo; Alessandro Sette
Prominent roles of secondary anchor residues in peptide binding to HLA-A24 human class I molecules.
Journal of immunology (Baltimore, Md. : 1950) 1995;155(9):4307-12.
1995: PA Wentworth; E Celis; Claire Crimi; S Stitely; L Hale; V Tsai; H M Serra; Marie-France del Guercio; Brian D Livingston; D Alazard; John Fikes; RT Kubo; Howard Grey; Robert W Chesnut; Francis V Chisari; Alessandro Sette
In vitro induction of primary, antigen-specific CTL from human peripheral blood mononuclear cells stimulated with synthetic peptides.
Molecular immunology 1995;32(9):603-12.
1995: Maaike E Ressing; Alessandro Sette; RM Brandt; J Ruppert; PA Wentworth; M Hartman; Carla Oseroff; Howard Grey; Cornelis J M Melief; W Martin Kast
Human CTL epitopes encoded by human papillomavirus type 16 E6 and E7 identified through in vivo and in vitro immunogenicity studies of HLA-A*0201-binding peptides.
Journal of immunology (Baltimore, Md. : 1950) 1995;154(11):5934-43.
1995: Marie-France del Guercio; John Sidney; G Hermanson; C Perez; Howard Grey; RT Kubo; Alessandro Sette
Binding of a peptide antigen to multiple HLA alleles allows definition of an A2-like supertype.
Journal of immunology (Baltimore, Md. : 1950) 1995;154(2):685-93.
1995: Jeff Alexander; J Ruppert; Dawne M Page; S M Hedrick; A Franco; Glenn Ishioka; Howard Grey; Alessandro Sette
Antigen analogs as therapeutic agents.
Advances in experimental medicine and biology 1995;386():109-18.
1995: J Ruppert; A Franco; Jeff Alexander; K Snoke; Glenn Ishioka; Dawne M Page; Stephen M Hedrick; L Adorini; Howard Grey; Alessandro Sette
MHC blocking peptides and T-cell receptor antagonists: novel paths to selective immunosuppression?
Chemical immunology 1995;60():61-78.
1995: Antonella Vitiello; Glenn Ishioka; Howard Grey; R Rose; P Farness; R LaFond; L Yuan; Francis V Chisari; J Furze; R Bartholomeuz
Development of a lipopeptide-based therapeutic vaccine to treat chronic HBV infection. I. Induction of a primary cytotoxic T lymphocyte response in humans.
The Journal of clinical investigation 1995;95(1):341-9.
1995: Robert W Chesnut; Alessandro Sette; E Celis; PA Wentworth; RT Kubo; J Alexander; Glenn Ishioka; Antonella Vitiello; Howard Grey
Design and testing of peptide-based cytotoxic T-cell-mediated immunotherapeutics to treat infectious diseases and cancer.
Pharmaceutical biotechnology 1995;6():847-74.
1995: Howard Grey; J Ruppert; Antonella Vitiello; John Sidney; W Martin Kast; RT Kubo; Alessandro Sette
Class I MHC-peptide interactions: structural requirements and functional implications.
Cancer surveys 1995;22():37-49.
1994: Alessandro Sette; Antonella Vitiello; B Reherman; P Fowler; R Nayersina; W Martin Kast; Cornelis J M Melief; Carla Oseroff; L Yuan; J Ruppert; John Sidney; Marie-France del Guercio; Scott Southwood; RT Kubo; Robert W Chesnut; Howard Grey; Francis V Chisari
The relationship between class I binding affinity and immunogenicity of potential cytotoxic T cell epitopes.
Journal of immunology (Baltimore, Md. : 1950) 1994;153(12):5586-92.
1994: Alessandro Sette; John Sidney; Marie-France del Guercio; Scott Southwood; J Ruppert; Carol Dahlberg; Howard Grey; RT Kubo
Peptide binding to the most frequent HLA-A class I alleles measured by quantitative molecular binding assays.
Molecular immunology 1994;31(11):813-22.
1994: J Ruppert; RT Kubo; John Sidney; Howard Grey; Alessandro Sette
Class I MHC-peptide interaction: structural and functional aspects.
Behring Institute Mitteilungen 1994;(94):48-60.
1994: Glenn Ishioka; L Adorini; J C Guery; F C Gaeta; R LaFond; Jeff Alexander; M F Powell; Alessandro Sette; Howard Grey
Failure to demonstrate long-lived MHC saturation both in vitro and in vivo. Implications for therapeutic potential of MHC-blocking peptides.
Journal of immunology (Baltimore, Md. : 1950) 1994;152(9):4310-9.
1994: Dawne M Page; Jeff Alexander; K Snoke; E Appella; Alessandro Sette; Stephen M Hedrick; Howard Grey
Negative selection of CD4+ CD8+ thymocytes by T-cell receptor peptide antagonists.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(9):4057-61.
1994: R T Kubo; Alessandro Sette; Howard Grey; Ettore Appella; K Sakaguchi; N Z Zhu; D Arnott; N Sherman; J Shabanowitz; H Michel
Definition of specific peptide motifs for four major HLA-A alleles.
Journal of immunology (Baltimore, Md. : 1950) 1994;152(8):3913-24.
1994: W Martin Kast; RM Brandt; J Sidney; Jan Wouter Drijfhout; R T Kubo; Howard Grey; Cornelis J M Melief; Alessandro Sette
Role of HLA-A motifs in identification of potential CTL epitopes in human papillomavirus type 16 E6 and E7 proteins.
Journal of immunology (Baltimore, Md. : 1950) 1994;152(8):3904-12.
1994: A Franco; Scott Southwood; T Arrhenius; V K Kuchroo; Howard Grey; Alessandro Sette; Glenn Ishioka
T cell receptor antagonist peptides are highly effective inhibitors of experimental allergic encephalomyelitis.
European journal of immunology 1994;24(4):940-6.
1994: E Celis; V Tsai; Claire Crimi; R DeMars; PA Wentworth; Robert W Chesnut; Howard Grey; Alessandro Sette; H M Serra
Induction of anti-tumor cytotoxic T lymphocytes in normal humans using primary cultures and synthetic peptide epitopes.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(6):2105-9.
1994: Alessandro Sette; Jeff Alexander; J Ruppert; K Snoke; A Franco; Glenn Ishioka; Howard Grey
Antigen analogs/MHC complexes as specific T cell receptor antagonists.
Annual review of immunology 1994;12():413-31.
1993: K Snoke; J Alexander; A Franco; L Smith; J V Brawley; Patrick Concannon; Howard Grey; Alessandro Sette; PA Wentworth
The inhibition of different T cell lines specific for the same antigen with TCR antagonist peptides.
Journal of immunology (Baltimore, Md. : 1950) 1993;151(12):6815-21.
1993: Alessandro Sette; John Sidney; Carla Oseroff; Marie-France del Guercio; Scott Southwood; T Arrhenius; M F Powell; S M Colón; F C Gaeta; Howard Grey
HLA DR4w4-binding motifs illustrate the biochemical basis of degeneracy and specificity in peptide-DR interactions.
Journal of immunology (Baltimore, Md. : 1950) 1993;151(6):3163-70.
1993: J Ruppert; John Sidney; E Celis; RT Kubo; Howard Grey; Alessandro Sette
Prominent role of secondary anchor residues in peptide binding to HLA-A2.1 molecules.
Cell 1993;74(5):929-37.
1993: J Ruppert; Jeff Alexander; K Snoke; M Coggeshall; E Herbert; D McKenzie; Howard Grey; Alessandro Sette
Effect of T-cell receptor antagonism on interaction between T cells and antigen-presenting cells and on T-cell signaling events.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(7):2671-5.
1993: Howard Grey; Jeff Alexander; K Snoke; Alessandro Sette; J Ruppert
Antigen analogues as antagonists of the T cell receptor.
Clinical and experimental rheumatology 1993;11 Suppl 8():S47-50.
1993: Alessandro Sette; R DeMars; Howard Grey; Carla Oseroff; Scott Southwood; Ettore Appella; RT Kubo; D F Hunt
Isolation and characterization of naturally processed peptides bound by class II molecules and peptides presented by normal and mutant antigen-presenting cells.
Chemical immunology 1993;57():152-65.
1993: Glenn Ishioka; A G Lamont; D Thomson; N Bulbow; F C Gaeta; Alessandro Sette; Howard Grey
Major histocompatibility complex class II association and induction of T cell responses by carbohydrates and glycopeptides.
Springer seminars in immunopathology 1993;15(2-3):293-302.
1992: M F Powell; Howard Grey; F Gaeta; Alessandro Sette; S Colón
Peptide stability in drug development: a comparison of peptide reactivity in different biological media.
Journal of pharmaceutical sciences 1992;81(8):731-5.
1992: Glenn Ishioka; A G Lamont; D Thomson; N Bulbow; F C Gaeta; Alessandro Sette; Howard Grey
MHC interaction and T cell recognition of carbohydrates and glycopeptides.
Journal of immunology (Baltimore, Md. : 1950) 1992;148(8):2446-51.
1992: M T De Magistris; Jeff Alexander; M Coggeshall; A Altman; F C Gaeta; Howard Grey; Alessandro Sette
Antigen analog-major histocompatibility complexes act as antagonists of the T cell receptor.
Cell 1992;68(4):625-34.
1992: Alessandro Sette; Scott Southwood; D O'Sullivan; F C Gaeta; John Sidney; Howard Grey
Effect of pH on MHC class II-peptide interactions.
Journal of immunology (Baltimore, Md. : 1950) 1992;148(3):844-51.
1991: Alessandro Sette; Antonella Vitiello; P Farness; J Furze; John Sidney; J M Claverie; Howard Grey; R Chesnut
Random association between the peptide repertoire of A2.1 class I and several different DR class II molecules.
Journal of immunology (Baltimore, Md. : 1950) 1991;147(11):3893-900.
1991: S Demotz; Alessandro Sette; K Sakaguchi; R Buchner; E Appella; Howard Grey
Self peptide requirement for class II major histocompatibility complex allorecognition.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(19):8730-4.
1991: Alessandro Sette; D O'Sullivan; J I Krieger; R W Karr; A G Lamont; Howard Grey
MHC-antigen-T cell interactions: an overview.
Seminars in immunology 1991;3(4):195-202.
1991: T Pedrazzini; Alessandro Sette; M Albertson; Howard Grey
Free ligand-induced dissociation of MHC-antigen complexes.
Journal of immunology (Baltimore, Md. : 1950) 1991;146(10):3496-501.
1991: J I Krieger; R W Karr; Howard Grey; W Y Yu; D O'Sullivan; L Batovsky; Z L Zheng; S M Colón; F C Gaeta; John Sidney
Single amino acid changes in DR and antigen define residues critical for peptide-MHC binding and T cell recognition.
Journal of immunology (Baltimore, Md. : 1950) 1991;146(7):2331-40.
1990: Alessandro Sette; John Sidney; M Albertson; C Miles; S M Colón; T Pedrazzini; A G Lamont; Howard Grey
A novel approach to the generation of high affinity class II-binding peptides.
Journal of immunology (Baltimore, Md. : 1950) 1990;145(6):1809-13.
1990: A G Lamont; Alessandro Sette; R Fujinami; S M Colón; C Miles; Howard Grey
Inhibition of experimental autoimmune encephalomyelitis induction in SJL/J mice by using a peptide with high affinity for IAs molecules.
Journal of immunology (Baltimore, Md. : 1950) 1990;145(6):1687-93.
1990: A G Lamont; M F Powell; S M Colón; C Miles; Howard Grey; Alessandro Sette
The use of peptide analogs with improved stability and MHC binding capacity to inhibit antigen presentation in vitro and in vivo.
Journal of immunology (Baltimore, Md. : 1950) 1990;144(7):2493-8.
1990: A G Lamont; Alessandro Sette; Howard Grey
Inhibition of antigen presentation in vitro and in vivo by MHC antagonist peptides.
International reviews of immunology 1990;6(1):49-59.
1989: Alessandro Sette; A Lamont; Soren Buus; S M Colon; C Miles; Howard Grey
Effect of conformational propensity of peptide antigens in their interaction with MHC class II molecules. Failure to document the importance of regular secondary structures.
Journal of immunology (Baltimore, Md. : 1950) 1989;143(4):1268-73.
1989: Alessandro Sette; L Adorini; S M Colon; Soren Buus; Howard Grey
Capacity of intact proteins to bind to MHC class II molecules.
Journal of immunology (Baltimore, Md. : 1950) 1989;143(4):1265-7.
1989: Glenn Ishioka; S Colon; C Miles; Howard Grey; Robert W Chesnut
Induction of class I MHC-restricted, peptide-specific cytolytic T lymphocytes by peptide priming in vivo.
Journal of immunology (Baltimore, Md. : 1950) 1989;143(4):1094-100.
1989: Howard Grey; Soren Buus; S Colon; C Miles; Alessandro Sette
Structural requirements and biological significance of interactions between peptides and the major histocompatibility complex.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 1989;323(1217):545-52.
1989: E B Schaeffer; Alessandro Sette; D L Johnson; M C Bekoff; J A Smith; Howard Grey; Soren Buus
Relative contribution of "determinant selection" and "holes in the T-cell repertoire" to T-cell responses.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(12):4649-53.
1989: Alessandro Sette; Soren Buus; E Appella; J A Smith; R Chesnut; C Miles; S M Colon; Howard Grey
Prediction of major histocompatibility complex binding regions of protein antigens by sequence pattern analysis.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(9):3296-300.
1989: D L Hamilos; J J Mascali; Robert W Chesnut; R M Young; Glenn Ishioka; Howard Grey
The role of dendritic cells as stimulators of minor lymphocyte-stimulating locus-specific T cell responses in the mouse. I. Differential capacity of dendritic cells to stimulate minor lymphocyte-stimulating locus-reactive T cell hybridomas and the primary anti-minor lymphocyte-stimulating locus mixed lymphocyte reaction.
Journal of immunology (Baltimore, Md. : 1950) 1989;142(4):1069-78.
1989: Howard Grey; S Demotz; Soren Buus; Alessandro Sette
Studies on the nature of physiologically processed antigen and on the conformation of peptides required for interaction with MHC.
Cold Spring Harbor symposia on quantitative biology 1989;54 Pt 1():393-9.
1989: Alessandro Sette; Soren Buus; S Colon; C Miles; Howard Grey
Structural analysis of peptides capable of binding to more than one Ia antigen.
Journal of immunology (Baltimore, Md. : 1950) 1989;142(1):35-40.
1988: Alessandro Sette; Soren Buus; S Colon; C Miles; Howard Grey
I-Ad-binding peptides derived from unrelated protein antigens share a common structural motif.
Journal of immunology (Baltimore, Md. : 1950) 1988;141(1):45-8.
1988: J Krieger; D M Jenis; Robert W Chesnut; Howard Grey
Studies on the capacity of intact cells and purified Ia from different B cell sources to function in antigen presentation to T cells.
Journal of immunology (Baltimore, Md. : 1950) 1988;140(2):388-94.
1987: M C Bekoff; B C Cole; Howard Grey
Studies on the mechanism of stimulation of T cells by the Mycoplasma arthritidis-derived mitogen. Role of class II IE molecules.
Journal of immunology (Baltimore, Md. : 1950) 1987;139(10):3189-94.
1986: Soren Buus; S Colon; C Smith; J H Freed; C Miles; Howard Grey
Interaction between a "processed" ovalbumin peptide and Ia molecules.
Proceedings of the National Academy of Sciences of the United States of America 1986;83(11):3968-71.
1982: R W Chesnut; S M Colon; Howard Grey
Requirements for the processing of antigens by antigen-presenting B cells. I. Functional comparison of B cell tumors and macrophages.
Journal of immunology (Baltimore, Md. : 1950) 1982;129(6):2382-8.
1982: Howard Grey; S M Colon; R W Chesnut
Requirements for the processing of antigen by antigen-presenting B cells. II. Biochemical comparison of the fate of antigen in B cell tumors and macrophages.
Journal of immunology (Baltimore, Md. : 1950) 1982;129(6):2389-95.
1982: R W Chesnut; S M Colon; Howard Grey
Antigen presentation by normal B cells, B cell tumors, and macrophages: functional and biochemical comparison.
Journal of immunology (Baltimore, Md. : 1950) 1982;128(4):1764-8.