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John Gribben

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Teresa Marafioti; Noraidah Masir; Elizabeth P Nacheva; Jennifer C Paterson; Pier Paolo Piccaluga; Stefano A Pileri; Alan D Ramsay; Kandavel Shanmugam; Vishvesh H Shende; Pierre Sujobert; William Townsend; Claudio Agostinelli; Kirit Ardeshna; Maryse Baia; Josette Brière; Simon P Brooks; Maria Calaminici; Andrew Clear; Christiane Copie-Bergman; Ming-Qing Du; Philippe Gaulard; John G Gribben; Thomas M Grogan; Corinne Haioun; Asim Khwaja; David Linch; Hongxiang Liu; Peter G Isaacson
Another look at follicular lymphoma: immunophenotypic and molecular analyses identify distinct follicular lymphoma subgroups.
Alan G Ramsay; Lena Svensson; Rachel Evans; Nancy Hogg; Shahryar Kiaii; John G Gribben
Chronic lymphocytic leukemia cells induce defective LFA-1-directed T-cell motility by altering Rho GTPase signaling that is reversible with lenalidomide.
John C Riches; John G Gribben
Understanding the immunodeficiency in chronic lymphocytic leukemia: potential clinical implications.

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2013: Teresa Marafioti; Noraidah Masir; Elizabeth P Nacheva; Jennifer C Paterson; Pier Paolo Piccaluga; Stefano A Pileri; Alan D Ramsay; Kandavel Shanmugam; Vishvesh H Shende; Pierre Sujobert; William Townsend; Claudio Agostinelli; Kirit Ardeshna; Maryse Baia; Josette Brière; Simon P Brooks; Maria Calaminici; Andrew Clear; Christiane Copie-Bergman; Ming-Qing Du; Philippe Gaulard; John G Gribben; Thomas M Grogan; Corinne Haioun; Asim Khwaja; David Linch; Hongxiang Liu; Peter G Isaacson
Another look at follicular lymphoma: immunophenotypic and molecular analyses identify distinct follicular lymphoma subgroups.
Histopathology 2013;62(6):860-75.
2013: Alan G Ramsay; Lena Svensson; Rachel Evans; Nancy Hogg; Shahryar Kiaii; John G Gribben
Chronic lymphocytic leukemia cells induce defective LFA-1-directed T-cell motility by altering Rho GTPase signaling that is reversible with lenalidomide.
Blood 2013;121(14):2704-14.
2013: John C Riches; John G Gribben
Understanding the immunodeficiency in chronic lymphocytic leukemia: potential clinical implications.
Hematology/oncology clinics of North America 2013;27(2):207-35.
2013: Sunil Iyengar; Abigail Lee; Lenushka Maharaj; Janet Matthews; Rebecca Auer; Csaba Bödör; Maria Calaminici; Andrew Clear; John G Gribben; Sameena Iqbal; Simon P Joel
P110α-mediated constitutive PI3K signaling limits the efficacy of p110δ-selective inhibition in mantle cell lymphoma, particularly with multiple relapse.
Blood 2013;121(12):2274-84.
2013: John C Riches; Sameena Iqbal; Fabienne McClanahan; Alan G Ramsay; Samir Agrawal; Jeffrey K Davies; Rewas Fatah; John G Gribben
T cells from CLL patients exhibit features of T-cell exhaustion but retain capacity for cytokine production.
Blood 2013;121(9):1612-21.
2013: Paul Greaves; John G Gribben
The role of B7 family molecules in hematologic malignancy.
Blood 2013;121(5):734-44.
2013: Paul Greaves; Maria Calaminici; Andrew Clear; Rita Coutinho; T Andrew Lister; Janet Matthews; Andrew Owen; Milensu Shanyinde; Andrew Wilson; John G Gribben
Expression of FOXP3, CD68, and CD20 at diagnosis in the microenvironment of classical Hodgkin lymphoma is predictive of outcome.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2013;31(2):256-62.
2012: Silvia Montoto; Jessica Okosun; Chloe Orkin; Milensu Shanyinde; Kate Shaw; Melinda Tenant-Flowers; Andrew Wilson; Anna Marie Young; Daniella Chilton; Kate Cwynarski; Johannes de Vos; Paul Fields; Shreyans Gandhi; John G Gribben; Margaret Johnson; Robert Marcus; Mark Bower
HIV status does not influence outcome in patients with classical Hodgkin lymphoma treated with chemotherapy using doxorubicin, bleomycin, vinblastine, and dacarbazine in the highly active antiretroviral therapy era.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2012;30(33):4111-6.
2012: Fabienne McClanahan; John G Gribben
Immunotherapeutic approaches have the potential to brighten the future not only for patients with del(17p13.1), but for all CLL patients.
Oncology (Williston Park, N.Y.) 2012;26(11):1055, 1058.
2012: Alan G Ramsay; Andrew J Clear; Rewas Fatah; John G Gribben
Multiple inhibitory ligands induce impaired T-cell immunologic synapse function in chronic lymphocytic leukemia that can be blocked with lenalidomide: establishing a reversible immune evasion mechanism in human cancer.
Blood 2012;120(7):1412-21.
2012: John C Riches; John G Gribben
Less expensive CARs?
Cytotherapy 2012;14(7):773-4.
2012: Rebecca L Auer; Jamie Cavenagh; Jeff K Davies; T Andrew Lister; Finlay MacDougall; Heather Oakervee; Denise Syndercombe-Court; David C Taussig; Samir Agrawal; John G Gribben
T-cell replete fludarabine/cyclophosphamide reduced intensity allogeneic stem cell transplantation for lymphoid malignancies.
British journal of haematology 2012;157(5):580-5.
2012: Neerav M Joshi; Louise Langmead; Heather Oakervee; David S Rampton; Matthew Smith; Samir A Agrawal; Rebecca Auer; Jamie Cavenagh; Johannes de Vos; Steve Dixon; John G Gribben; Sandra Hassan; Parag Jasani; David C Taussig
Bile acid malabsorption in patients with graft-versus-host disease of the gastrointestinal tract.
British journal of haematology 2012;157(3):403-7.
2012: Paul Greaves; Rebecca Auer; Daniel L P Brown; T Andrew Lister; Janet Matthews; Silvia Montoto; Andrew Wilson; John G Gribben
Early relapse and refractory disease remain risk factors in the anthracycline and autologous transplant era for patients with relapsed/refractory classical Hodgkin lymphoma: a single centre intention-to-treat analysis.
British journal of haematology 2012;157(2):201-4.
2012: J Vargaftig; Fernando Anjos-Afonso; Jamie Cavenagh; John G Gribben; E Griessinger; T Andrew Lister; Heather Oakervee; David C Taussig; Dominique Bonnet
Frequency of leukemic initiating cells does not depend on the xenotransplantation model used.
Leukemia 2012;26(4):858-60.
2012: John C Riches; Alan G Ramsay; John G Gribben
Immune reconstitution in chronic lymphocytic leukemia.
Current hematologic malignancy reports 2012;7(1):13-20.
2012: Li Jia; Johanna T Sukumar; Ganga Gopinathan; John G Gribben
Blocking autophagy prevents bortezomib-induced NF-κB activation by reducing I-κBα degradation in lymphoma cells.
PloS one 2012;7(2):e32584.
2011: John C Riches; Alan G Ramsay; John G Gribben
Chronic lymphocytic leukemia: an update on biology and treatment.
Current oncology reports 2011;13(5):379-85.
2011: Timothy W Farren; Jerome Giustiniani; John G Gribben; Michael J Jenner; Feng-Ting Liu; Marion G Macey; Adrian C Newland; Heather Oakervee; David C Taussig; Dimitris A Tsitsikas; Armand Bensussan; Maria Calaminici; Jamie Cavenagh; Samir G Agrawal
Differential and tumor-specific expression of CD160 in B-cell malignancies.
Blood 2011;118(8):2174-83.
2011: David Wrench; Pamela Leighton; Christine F Skibola; Lucia Conde; Jean-Baptiste Cazier; Janet Matthews; Sameena Iqbal; Emanuela Carlotti; Csaba Bödör; Silvia Montoto; Maria Calaminici; John G Gribben; T Andrew Lister; Jude Fitzgibbon
SNP rs6457327 in the HLA region on chromosome 6p is predictive of the transformation of follicular lymphoma.
Blood 2011;117(11):3147-50.
2011: John G Gribben; Susan O'Brien
Update on therapy of chronic lymphocytic leukemia.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2011;29(5):544-50.
2011: John G Gribben; Chitra Hosing; David G Maloney
Stem cell transplantation for indolent lymphoma and chronic lymphocytic leukemia.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2011;17(1 Suppl):S63-70.
2010: John C Riches; Alan G Ramsay; John G Gribben
T-cell function in chronic lymphocytic leukaemia.
Seminars in cancer biology 2010;20(6):431-8.
2010: Maike Buchner; Philipp Brantner; Natalie Stickel; Gabriele Prinz; Meike Burger; Constance Bär; Christine Dierks; Dietmar Pfeifer; Ariane Ott; Roland Mertelsmann; John G Gribben; Hendrik Veelken; Katja Zirlik
The microenvironment differentially impairs passive and active immunotherapy in chronic lymphocytic leukaemia - CXCR4 antagonists as potential adjuvants for monoclonal antibodies.
British journal of haematology 2010;151(2):167-78.
2010: John G Gribben
Chronic lymphocytic leukemia: planning for an aging population.
Expert review of anticancer therapy 2010;10(9):1389-94.
2010: John G Gribben
Implications of the tumor microenvironment on survival and disease response in follicular lymphoma.
Current opinion in oncology 2010;22(5):424-30.
2010: Andrew J Clear; Abigail M Lee; Maria Calaminici; Alan G Ramsay; Kelly J Morris; Simon Hallam; Gavin Kelly; Finlay Macdougall; T Andrew Lister; John G Gribben
Increased angiogenic sprouting in poor prognosis FL is associated with elevated numbers of CD163+ macrophages within the immediate sprouting microenvironment.
Blood 2010;115(24):5053-6.
2010: Tom Butler; John G Gribben
Biologic and clinical significance of molecular profiling in Chronic Lymphocytic Leukemia.
Blood reviews 2010;24(3):135-41.
2010: Feng-Ting Liu; Jerome Giustiniani; Timothy Farren; Li Jia; Armand Bensussan; John G Gribben; Samir G Agrawal
CD160 signaling mediates PI3K-dependent survival and growth signals in chronic lymphocytic leukemia.
Blood 2010;115(15):3079-88.
2010: Alan G Ramsay; John G Gribben
The 3 Rs in CLL immune dysfunction.
Blood 2010;115(13):2563-4.
2010: David C Taussig; Jacques Vargaftig; Farideh Miraki-Moud; Emmanuel Griessinger; Kirsty Sharrock; Tina Luke; Debra M Lillington; Heather Oakervee; Jamie Cavenagh; Samir G Agrawal; T Andrew Lister; John G Gribben; Dominique Bonnet
Leukemia-initiating cells from some acute myeloid leukemia patients with mutated nucleophosmin reside in the CD34(-) fraction.
Blood 2010;115(10):1976-84.
2010: Simon Hallam; John G Gribben
Stem cell transplantation in chronic lymphocytic leukaemia - steering a safe course over shifting sands.
Best practice & research. Clinical haematology 2010;23(1):109-19.
2010: John G Gribben
How I treat CLL up front.
Blood 2010;115(2):187-97.
2009: Alan G Ramsay; Andrew J Clear; Gavin Kelly; Rewas Fatah; Janet Matthews; Finlay Macdougall; T Andrew Lister; Abigail M Lee; Maria Calaminici; John G Gribben
Follicular lymphoma cells induce T-cell immunologic synapse dysfunction that can be repaired with lenalidomide: implications for the tumor microenvironment and immunotherapy.
Blood 2009;114(21):4713-20.
2009: John C Riches; John G Gribben
Interesting times in the diagnosis and treatment of CLL.
Oncology (Williston Park, N.Y.) 2009;23(12):1043, 1046.
2009: Rifca Le Dieu; David C Taussig; Alan G Ramsay; Richard Mitter; Farideh Miraki-Moud; Rewas Fatah; Abigail M Lee; T Andrew Lister; John G Gribben
Peripheral blood T cells in acute myeloid leukemia (AML) patients at diagnosis have abnormal phenotype and genotype and form defective immune synapses with AML blasts.
Blood 2009;114(18):3909-16.
2009: Emanuela Carlotti; John G Gribben
Stem cell mimicry: key to transformation?
Blood 2009;114(15):3133-4.
2009: C O'Riain; D M O'Shea; Y Yang; R Le Dieu; John G Gribben; K Summers; J Yeboah-Afari; L Bhaw-Rosun; C Fleischmann; Charles A Mein; T Crook; P Smith; G Kelly; A Rosenwald; G Ott; E Campo; Lisa M Rimsza; Erlend Smeland; Wing C Chan; N Johnson; Randy D Gascoyne; S Reimer; Rita M Braziel; G W Wright; L M Staudt; T Andrew Lister; Jude Fitzgibbon
Array-based DNA methylation profiling in follicular lymphoma.
Leukemia 2009;23(10):1858-66.
2009: Rifca Le Dieu; David Taussig; T Andrew Lister; John G Gribben
Negative immunomagnetic selection of T cells from peripheral blood of presentation AML specimens.
Journal of immunological methods 2009;348(1-2):95-100.
2009: Gullu Gorgun; Alan G Ramsay; Tobias A W Holderried; David Zahrieh; Rifca Le Dieu; Fenglong Liu; John Quackenbush; Carlo M Croce; John G Gribben
E(mu)-TCL1 mice represent a model for immunotherapeutic reversal of chronic lymphocytic leukemia-induced T-cell dysfunction.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(15):6250-5.
2009: Derville O'Shea; Ciarán O'Riain; Manu Gupta; Rachel Waters; Youwen Yang; David Wrench; John G Gribben; Andreas Rosenwald; German Ott; Lisa M Rimsza; Harald Holte; Jean-Baptiste Cazier; Nathalie A Johnson; Elias Campo; Wing C Chan; Randy D Gascoyne; Bryan D Young; Louis M Staudt; T Andrew Lister; Jude Fitzgibbon
Regions of acquired uniparental disomy at diagnosis of follicular lymphoma are associated with both overall survival and risk of transformation.
Blood 2009;113(10):2298-301.
2009: John G Gribben; Michael Hallek
Rediscovering alemtuzumab: current and emerging therapeutic roles.
British journal of haematology 2009;144(6):818-31.
2009: Bradley T Messmer; Benjamin J Raphael; Sarah J Aerni; George F Widhopf; Laura Z Rassenti; John G Gribben; Neil E Kay; Thomas Kipps
Computational identification of CDR3 sequence archetypes among immunoglobulin sequences in chronic lymphocytic leukemia.
Leukemia research 2009;33(3):368-76.
2009: Simon Hallam; John G Gribben
Transplantation in chronic lymphocytic leukemia: timing and expectations.
Clinical lymphoma & myeloma 2009;9 Suppl 3():S186-93.
2009: John G Gribben
Stem cell transplantation in chronic lymphocytic leukemia.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2009;15(1 Suppl):53-8.
2008: Feng-Ting Liu; Samir G Agrawal; Zanyar Movasaghi; Peter B Wyatt; Ihtesham U Rehman; John G Gribben; Adrian C Newland; Li Jia
Dietary flavonoids inhibit the anticancer effects of the proteasome inhibitor bortezomib.
Blood 2008;112(9):3835-46.
2008: John G Gribben
Role of allogeneic hematopoietic stem-cell transplantation in chronic lymphocytic leukemia.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2008;26(30):4864-5.
2008: David Wrench; John G Gribben
Stem cell transplantation for non-Hodgkin's lymphoma.
Hematology/oncology clinics of North America 2008;22(5):1051-79, xi.
2008: jeff davies; John G Gribben; Lisa L Brennan; Dongin Yuk; Lee M Nadler; Eva C Guinan
Outcome of alloanergized haploidentical bone marrow transplantation after ex vivo costimulatory blockade: results of 2 phase 1 studies.
Blood 2008;112(6):2232-41.
2008: Alan G Ramsay; John G Gribben
Vaccine therapy and chronic lymphocytic leukaemia.
Best practice & research. Clinical haematology 2008;21(3):421-36.
2008: Laura Z Rassenti; Sonia Jain; Michael J Keating; William G Wierda; Michael R Grever; John C Byrd; Neil E Kay; Jennifer R Brown; John G Gribben; Donna S Neuberg; Feng He; Andrew W Greaves; Kanti Rai; Thomas Kipps
Relative value of ZAP-70, CD38, and immunoglobulin mutation status in predicting aggressive disease in chronic lymphocytic leukemia.
Blood 2008;112(5):1923-30.
2008: David C Taussig; Farideh Miraki-Moud; Fernando Anjos-Afonso; Daniel J Pearce; Kirsty Allen; Christopher Ridler; Debra M Lillington; Heather Oakervee; Jamie Cavenagh; Samir G Agrawal; T Andrew Lister; John G Gribben; Dominique Bonnet
Anti-CD38 antibody-mediated clearance of human repopulating cells masks the heterogeneity of leukemia-initiating cells.
Blood 2008;112(3):568-75.
2008: Rodrigo Proto-Siqueira; Rodrigo A Panepucci; Francisco de Paula Careta; Abigail Lee; Andrew Clear; Kelly Morris; Carolyn Owen; Edgar G Rizzatti; Wilson Araújo Silva Jr; Roberto P Falcão; Marco Zago; John G Gribben
SAGE analysis demonstrates increased expression of TOSO contributing to Fas-mediated resistance in CLL.
Blood 2008;112(2):394-7.
2008: Alan G Ramsay; Amy J Johnson; Abigail M Lee; Güllü Gorgün; Rifca Le Dieu; William Blum; John C Byrd; John G Gribben
Chronic lymphocytic leukemia T cells show impaired immunological synapse formation that can be reversed with an immunomodulating drug.
The Journal of clinical investigation 2008;118(7):2427-37.
2008: John G Gribben
New agents in chronic lymphocytic leukemia.
Clinical advances in hematology & oncology : H&O 2008;6(6):409-10, 468.
2008: Emanuela M Ghia; Sonia Jain; George F Widhopf; Laura Rassenti; Michael J Keating; William G Wierda; John G Gribben; Jennifer R Brown; Kanti Rai; John C Byrd; Neil E Kay; Andrew W Greaves; Thomas Kipps
Use of IGHV3-21 in chronic lymphocytic leukemia is associated with high-risk disease and reflects antigen-driven, post-germinal center leukemogenic selection.
Blood 2008;111(10):5101-8.
2008: Maria H Gilleece; Rachel Pearce; David C Linch; Marie Wilson; Keiren Towlson; Stephen Mackinnon; Michael Potter; Majid Kazmi; John G Gribben; David I Marks
The outcome of haemopoietic stem cell transplantation in the treatment of lymphoplasmacytic lymphoma in the UK: a British Society Bone Marrow Transplantation study.
Hematology (Amsterdam, Netherlands) 2008;13(2):119-27.
2008: George F Widhopf; Craig J Goldberg; Traci L Toy; Laura Rassenti; William G Wierda; John C Byrd; Michael J Keating; John G Gribben; Kanti Rai; Thomas Kipps
Nonstochastic pairing of immunoglobulin heavy and light chains expressed by chronic lymphocytic leukemia B cells is predicated on the heavy chain CDR3.
Blood 2008;111(6):3137-44.
2008: Tom Butler; John G Gribben
Biologic prognostic markers and their application in clinical trials and management of chronic lymphocytic leukaemia patients.
Expert opinion on medical diagnostics 2008;2(1):101-12.
2007: Jennifer R Brown; Yang Feng; John G Gribben; Donna Neuberg; David C Fisher; Peter M Mauch; Lee M Nadler; Arnold S Freedman
Long-term survival after autologous bone marrow transplantation for follicular lymphoma in first remission.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2007;13(9):1057-65.
2007: Jianbiao Zhou; Meredith A Goldwasser; Aihong Li; Suzanne E Dahlberg; Donna Neuberg; Hongjun Wang; Virginia Dalton; Kathryn D McBride; Stephen E Sallan; Lewis B Silverman; John G Gribben
Quantitative analysis of minimal residual disease predicts relapse in children with B-lineage acute lymphoblastic leukemia in DFCI ALL Consortium Protocol 95-01.
Blood 2007;110(5):1607-11.
2007: Rifca Le Dieu; John G Gribben
Transplantation in chronic lymphocytic leukemia.
Current hematologic malignancy reports 2007;2(1):56-63.
2006: Jennifer R Brown; Haesook T Kim; Shuli Li; Katherine Stephans; David C Fisher; Corey Cutler; Vincent T Ho; Stephanie J Lee; Edgar L Milford; Jerome Ritz; Joseph H Antin; Robert J Soiffer; John G Gribben; Edwin P Alyea
Predictors of improved progression-free survival after nonmyeloablative allogeneic stem cell transplantation for advanced chronic lymphocytic leukemia.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2006;12(10):1056-64.
2006: Vincent T Ho; Haesook T Kim; Deborah Liney; Edgar L Milford; John G Gribben; Corey Cutler; Stephanie J Lee; Joseph H Antin; Robert J Soiffer; Edwin P Alyea
HLA-C mismatch is associated with inferior survival after unrelated donor non-myeloablative hematopoietic stem cell transplantation.
Bone marrow transplantation 2006;37(9):845-50.
2005: John G Gribben; David Zahrieh; Katherine Stephans; Lini Bartlett-Pandite; Edwin P Alyea; David C Fisher; Arnold S Freedman; Peter M Mauch; Robert Schlossman; Lecia V Sequist; Robert J Soiffer; Blossom Marshall; Donna Neuberg; Jerome Ritz; Lee M Nadler
Autologous and allogeneic stem cell transplantations for poor-risk chronic lymphocytic leukemia.
Blood 2005;106(13):4389-96.
2005: Aihong Li; Meredith A Goldwasser; Jianbiao Zhou; Scott A Armstrong; Hongjun Wang; Virginia Dalton; Jonathan A Fletcher; Stephen E Sallan; Lewis B Silverman; John G Gribben
Distinctive IGH gene segment usage and minimal residual disease detection in infant acute lymphoblastic leukaemias.
British journal of haematology 2005;131(2):185-92.
2005: Güllü Görgün; Tobias A W Holderried; David Zahrieh; Donna Neuberg; John G Gribben
Chronic lymphocytic leukemia cells induce changes in gene expression of CD4 and CD8 T cells.
The Journal of clinical investigation 2005;115(7):1797-805.
2005: John G Gribben; David P Ryan; Richard N. Boyajian; Robert G Urban; Mary Lynne Hedley; Kathleen Beach; Patrick Nealon; Ursula Matulonis; Susana Campos; Timothy D Gilligan; Paul G Richardson; Blossom Marshall; Donna Neuberg; Lee M Nadler
Unexpected association between induction of immunity to the universal tumor antigen CYP1B1 and response to next therapy.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(12):4430-6.
2005: Katja Mauerer; David Zahrieh; Gullu T Gorgun; Aihong Li; Jianbiao Zhou; Sascha Ansén; Laura Rassenti; John G Gribben
Immunoglobulin gene segment usage, location and immunogenicity in mutated and unmutated chronic lymphocytic leukaemia.
British journal of haematology 2005;129(4):499-510.
2005: Edwin P Alyea; Haesook T Kim; Vincent T Ho; Corey Cutler; John G Gribben; Daniel J DeAngelo; Stephanie J Lee; Sarah Windawi; Jerome Ritz; Richard M Stone; Joseph H Antin; Robert J Soiffer
Comparative outcome of nonmyeloablative and myeloablative allogeneic hematopoietic cell transplantation for patients older than 50 years of age.
Blood 2005;105(4):1810-4.
2005: Jianbiao Zhou; Katja Mauerer; Lucia Farina; John G Gribben
The role of the tumor microenvironment in hematological malignancies and implication for therapy.
Frontiers in bioscience : a journal and virtual library 2005;10():1581-96.
2004: Clair S Gricks; David Zahrieh; A Jason Zauls; Gullu T Gorgun; Daniela Drandi; Katja Mauerer; Donna Neuberg; John G Gribben
Differential regulation of gene expression following CD40 activation of leukemic compared to healthy B cells.
Blood 2004;104(13):4002-9.
2004: Aihong Li; Montse Rue; Jianbiao Zhou; Hongjun Wang; Meredith A Goldwasser; Donna Neuberg; Virginia Dalton; David Zuckerman; Cheryl Lyons; Lewis B Silverman; Stephen E Sallan; John G Gribben
Utilization of Ig heavy chain variable, diversity, and joining gene segments in children with B-lineage acute lymphoblastic leukemia: implications for the mechanisms of VDJ recombination and for pathogenesis.
Blood 2004;103(12):4602-9.
2004: Scott A Armstrong; Meghann E Mabon; Lewis B Silverman; Aihong Li; John G Gribben; Edward A Fox; Stephen E Sallan; Stanley J Korsmeyer
FLT3 mutations in childhood acute lymphoblastic leukemia.
Blood 2004;103(9):3544-6.
2004: Jennifer R Brown; Guylaine Gaudet; Jonathan W Friedberg; Donna Neuberg; Peter M Mauch; Jeffery L Kutok; Tak Takvorian; David C Fisher; John G Gribben; Helen Kim; Lee M Nadler; Arnold S Freedman
Autologous bone marrow transplantation for marginal zone non-Hodgkin's lymphoma.
Leukemia & lymphoma 2004;45(2):315-20.
2004: Zubair Abba; David Zahrieh; Heather Daley; Daryls Schott; John G Gribben; Edwin P Alyea; Robert Schlossman; Arnold S Freedman; Joseph H Antin; Robert J Soiffer; Donna Neuberg; Jerome Ritz
Engraftment of autologous and allogeneic marrow HPCs after myeloablative therapy.
Transfusion 2004;44(2):253-61.
2004: Jonathan W Friedberg; Danielle A Dong; Sigui Li; Helen Kim; Katherine Stephans; Kimberly Noonan; Donna Neuberg; John G Gribben; David C Fisher; Arnold S Freedman; Tak Takvorian; Ray Jurgens; Traci E Battle; David A Frank
Oral fludarabine has significant activity in patients with previously untreated chronic lymphocytic leukemia, and leads to increased STAT1 levels in vivo.
Leukemia research 2004;28(2):139-47.
2003: Aihong Li; Jianbiao Zhou; David Zuckerman; Montse Rue; Virginia Dalton; Cheryl Lyons; Lewis B Silverman; Stephen E Sallan; John G Gribben
Sequence analysis of clonal immunoglobulin and T-cell receptor gene rearrangements in children with acute lymphoblastic leukemia at diagnosis and at relapse: implications for pathogenesis and for the clinical utility of PCR-based methods of minimal residual disease detection.
Blood 2003;102(13):4520-6.
2003: Edwin P Alyea; Edie Weller; Robert Schlossman; Christine Canning; Peter M Mauch; Andrea K Ng; David C Fisher; John G Gribben; Andrea Freeman; Bijal Parikh; Paul Richardson; Robert J Soiffer; Jerome Ritz; Kenneth C Anderson
Outcome after autologous and allogeneic stem cell transplantation for patients with multiple myeloma: impact of graft-versus-myeloma effect.
Bone marrow transplantation 2003;32(12):1145-51.
2003: Jonathan W Friedberg; H Kim; Sigui Li; Donna Neuberg; K Boyd; Heather Daley; David C Fisher; John G Gribben; Thomas R Spitzer; Arnold S Freedman
Ex vivo B cell depletion using the Eligix B Cell SC system and autologous peripheral blood stem cell transplantation in patients with follicular non-Hodgkin's lymphoma.
Bone marrow transplantation 2003;32(7):681-6.
2003: Traci E Battle; Hugo Castro-Malaspina; John G Gribben; David A Frank
Sustained complete remission of CLL associated with the use of a Chinese herbal extract: case report and mechanistic analysis.
Leukemia research 2003;27(9):859-63.
2003: Vassiliki Rizouli; John G Gribben
Role of autologous stem cell transplantation in chronic lymphocytic leukemia.
Current opinion in hematology 2003;10(4):306-11.
2003: Zubair Abba; David Zahrieh; Heather Daley; Daryls Schott; John G Gribben; Arnold S Freedman; Jerome Ritz
Early neutrophil engraftment following autologous BMT provides a functional predictor of long-term hematopoietic reconstitution.
Transfusion 2003;43(5):614-21.
2003: Clair S Gricks; John G Gribben
Cytotoxic T cell responses against immunoglobulin in malignant and normal B cells: implications for tumor immunity and autoimmunity.
Current pharmaceutical design 2003;9(23):1889-903.
2002: Angela M Krackhardt; Mathias Witzens; Sabine Harig; F Stephen Hodi; A Jason Zauls; Morgan Chessia; Patrick Barrett; John G Gribben
Identification of tumor-associated antigens in chronic lymphocytic leukemia by SEREX.
Blood 2002;100(6):2123-31.
2002: Niels S Andersen; John W Donovan; Amy Zuckerman; Lone Pedersen; Christian Hartmann Geisler; John G Gribben
Real-time polymerase chain reaction estimation of bone marrow tumor burden using clonal immunoglobulin heavy chain gene and bcl-1/JH rearrangements in mantle cell lymphoma.
Experimental hematology 2002;30(7):703-10.
2002: Angela M Krackhardt; Sabine Harig; Mathias Witzens; Ryan Broderick; Patrick Barrett; John G Gribben
T-cell responses against chronic lymphocytic leukemia cells: implications for immunotherapy.
Blood 2002;100(1):167-73.
2002: marco ladetto; Paola Omedè; Selina Sametti; John W Donovan; Monica Astolfi; Daniela Drandi; Federica Volpato; Luisa Giaccone; Fulvia Giaretta; Antonio Palumbo; Benedetto Bruno; Alessandro Pileri; John G Gribben; Mario Boccadoro
Real-time polymerase chain reaction in multiple myeloma: quantitative analysis of tumor contamination of stem cell harvests.
Experimental hematology 2002;30(6):529-36.
2002: Jonathan W Friedberg; Donna Neuberg; John G Gribben; David C Fisher; Christine Canning; Margaret Koval; Christine M Poor; Luke M Green; John Daley; Robert J Soiffer; Jerome Ritz; Arnold S Freedman
Combination immunotherapy with rituximab and interleukin 2 in patients with relapsed or refractory follicular non-Hodgkin's lymphoma.
British journal of haematology 2002;117(4):828-34.
2002: John G Gribben
Monitoring disease in lymphoma and CLL patients using molecular techniques.
Best practice & research. Clinical haematology 2002;15(1):179-95.
2002: Orion M Howard; John G Gribben; Donna Neuberg; Michael L Grossbard; Christine M Poor; Milos J Janicek; Margaret A Shipp
Rituximab and CHOP induction therapy for newly diagnosed mantle-cell lymphoma: molecular complete responses are not predictive of progression-free survival.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2002;20(5):1288-94.
2002: Edwin P Alyea; Edie Weller; David C Fisher; Arnold S Freedman; John G Gribben; Stephanie Lee; Robert Schlossman; Richard M Stone; Jonathan W Friedberg; Daniel J DeAngelo; Deborah Liney; Sarah Windawi; Andrea K Ng; Peter M Mauch; Joseph H Antin; Robert J Soiffer
Comparable outcome with T-cell-depleted unrelated-donor versus related-donor allogeneic bone marrow transplantation.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2002;8(11):601-7.
2002: Iain Webb; nathan W Friedberg; John G Gribben; David C Fisher; Thomas R Spitzer; Donna Neuberg; Haddy Jallow; Helen Kim; Heather Houde; Ron Monroy; Robert Schmittling; Arnold S Freedman
Effective purging of autologous hematopoietic stem cells using anti-B-cell monoclonal antibody-coated high-density microparticles prior to high-dose therapy for patients with non-Hodgkin's lymphoma.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2002;8(8):429-34.
2002: Edwin P Alyea; Donna Neuberg; Peter M Mauch; Karen Marcus; Arnold S Freedman; Iain Webb; Kenneth C Anderson; Robert Schlossman; David C Fisher; John G Gribben; Jerome Ritz; Robert J Soiffer
Effect of total body irradiation dose escalation on outcome following T-cell-depleted allogeneic bone marrow transplantation.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2002;8(3):139-44.
2001: Sabine Harig; Mathias Witzens; Angela M Krackhardt; Andreas Trojan; Patrick Barrett; Ryan Broderick; A Jason Zauls; John G Gribben
Induction of cytotoxic T-cell responses against immunoglobulin V region-derived peptides modified at human leukocyte antigen-A2 binding residues.
Blood 2001;98(10):2999-3005.
2001: Robert H Vonderheide; Marcus O Butler; J F Liu; Traci E Battle; Naoto Hirano; John G Gribben; David A Frank; Joachim L Schultze; Lee M Nadler
CD40 activation of carcinoma cells increases expression of adhesion and major histocompatibility molecules but fails to induce either CD80/CD86 expression or T cell alloreactivity.
International journal of oncology 2001;19(4):791-8.
2001: Edwin P Alyea; Edie Weller; Robert Schlossman; Christine Canning; Iain Webb; Deborah Doss; Peter M Mauch; Karen Marcus; David C Fisher; Andrea Freeman; Bijal Parikh; John G Gribben; Robert J Soiffer; Jerome Ritz; Kenneth C Anderson
T-cell--depleted allogeneic bone marrow transplantation followed by donor lymphocyte infusion in patients with multiple myeloma: induction of graft-versus-myeloma effect.
Blood 2001;98(4):934-9.
2001: Robert H Vonderheide; Janice P Dutcher; J E Anderson; S Gail Eckhardt; Katherine Stephans; B Razvillas; Susan Garl; M D Butine; V P Perry; R J Armitage; RG Ghalie; D A Caron; John G Gribben
Phase I study of recombinant human CD40 ligand in cancer patients.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2001;19(13):3280-7.
2001: Andreas Trojan; Mathias Witzens; Joachim L Schultze; Robert H Vonderheide; Sabine Harig; Angela M Krackhardt; Rolf A Stahel; John G Gribben
Generation of cytotoxic T lymphocytes against native and altered peptides of human leukocyte antigen-A*0201 restricted epitopes from the human epithelial cell adhesion molecule.
Cancer research 2001;61(12):4761-5.
2001: Joachim L Schultze; Kenneth C Anderson; M H Gilleece; John G Gribben; Lee M Nadler
A pilot study of combined immunotherapy with autologous adoptive tumour-specific T-cell transfer, vaccination with CD40-activated malignant B cells and interleukin 2.
British journal of haematology 2001;113(2):455-60.
2001: Robert J Soiffer; Edie Weller; Edwin P Alyea; Peter M Mauch; I L Webb; David C Fisher; Arnold S Freedman; Robert Schlossman; John G Gribben; Sandra Lee; Kenneth C Anderson; Karen Marcus; Richard M Stone; Joseph H Antin; Jerome Ritz
CD6+ donor marrow T-cell depletion as the sole form of graft-versus-host disease prophylaxis in patients undergoing allogeneic bone marrow transplant from unrelated donors.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2001;19(4):1152-9.
2001: marco ladetto; Selina Sametti; John W Donovan; Dario Ferrero; Monica Astolfi; Manfred Mitterer; Irene Ricca; Daniela Drandi; Paolo Corradini; Paolo Coser; Alessandro Pileri; John G Gribben; Corrado Tarella
A validated real-time quantitative PCR approach shows a correlation between tumor burden and successful ex vivo purging in follicular lymphoma patients.
Experimental hematology 2001;29(2):183-93.
2000: J Donovan; Jennifer S Temel; A Zuckerman; John G Gribben; J Fang; G Pierson; A Ross; Lisa Diller; Stephan A Grupp
CD34 selection as a stem cell purging strategy for neuroblastoma: preclinical and clinical studies.
Medical and pediatric oncology 2000;35(6):677-82.
2000: Andreas Trojan; Joachim L Schultze; Mathias Witzens; Robert H Vonderheide; marco ladetto; John W Donovan; John G Gribben
Immunoglobulin framework-derived peptides function as cytotoxic T-cell epitopes commonly expressed in B-cell malignancies.
Nature medicine 2000;6(6):667-72.
2000: John W Donovan; marco ladetto; G Zou; Donna Neuberg; Christine M Poor; D Bowers; John G Gribben
Immunoglobulin heavy-chain consensus probes for real-time PCR quantification of residual disease in acute lymphoblastic leukemia.
Blood 2000;95(8):2651-8.
2000: Arnold S Freedman; J W Friedberg; John G Gribben
High-dose therapy for follicular lymphoma.
Oncology (Williston Park, N.Y.) 2000;14(3):321-6, 329; discussion 330-2, 338.
2000: marco ladetto; John W Donovan; Sabine Harig; Andreas Trojan; Christine M Poor; R Schlossnan; Kenneth C Anderson; John G Gribben
Real-Time polymerase chain reaction of immunoglobulin rearrangements for quantitative evaluation of minimal residual disease in multiple myeloma.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2000;6(3):241-53.
1999: Arnold S Freedman; Donna Neuberg; Peter M Mauch; Robert J Soiffer; Kenneth C Anderson; David C Fisher; Robert Schlossman; Edwin P Alyea; Tak Takvorian; Haddy Jallow; C Kuhlman; Jerome Ritz; Lee M Nadler; John G Gribben
Long-term follow-up of autologous bone marrow transplantation in patients with relapsed follicular lymphoma.
Blood 1999;94(10):3325-33.
1999: Angela M Krackhardt; John G Gribben
Stem cell transplantation for indolent lymphoma.
Current opinion in hematology 1999;6(6):388-93.
1999: Jonathan W Friedberg; Donna Neuberg; Richard M Stone; Edwin P Alyea; Haddy Jallow; Ann S LaCasce; Peter M Mauch; John G Gribben; Jerome Ritz; Lee M Nadler; Robert J Soiffer; Arnold S Freedman
Outcome in patients with myelodysplastic syndrome after autologous bone marrow transplantation for non-Hodgkin's lymphoma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1999;17(10):3128-35.
1999: Joachim L Schultze; John W Donovan; John G Gribben
Minimal residual disease detection after myeloablative chemotherapy in chronic lymphatic leukemia.
Journal of molecular medicine (Berlin, Germany) 1999;77(2):259-65.
1999: Joachim L Schultze; S Michalak; J Lowne; A Wong; M H Gilleece; John G Gribben; Lee M Nadler
Human non-germinal center B cell interleukin (IL)-12 production is primarily regulated by T cell signals CD40 ligand, interferon gamma, and IL-10: role of B cells in the maintenance of T cell responses.
The Journal of experimental medicine 1999;189(1):1-12.
1999: Jonathan W Friedberg; Donna Neuberg; John G Gribben; Peter M Mauch; Kenneth C Anderson; Robert J Soiffer; Tak Takvorian; David C Fisher; Robert Schlossman; Haddy Jallow; C Kuhlman; Jerome Ritz; Arnold S Freedman
Autologous bone marrow transplantation after histologic transformation of indolent B cell malignancies.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 1999;5(4):262-8.
1998: Joachim L Schultze; John G Gribben; Lee M Nadler
Tumor-specific adoptive T-cell therapy for CD40+ B-cell malignancies.
Current opinion in oncology 1998;10(6):542-7.
1998: John G Gribben
Molecular basis for stem cell transplantation in indolent lymphomas.
The cancer journal from Scientific American 1998;4 Suppl 2():S37-45.
1998: S Mach-Pascual; Robert D Legare; D Lu; M Kroon; Donna Neuberg; R Tantravahi; Richard M Stone; Arnold S Freedman; Lee M Nadler; John G Gribben; D Gary Gilliland
Predictive value of clonality assays in patients with non-Hodgkin's lymphoma undergoing autologous bone marrow transplant: a single institution study.
Blood 1998;91(12):4496-503.
1998: Robert J Soiffer; Arnold S Freedman; Donna Neuberg; David C Fisher; Edwin P Alyea; John G Gribben; Robert Schlossman; Lini Bartlett-Pandite; C Kuhlman; C Murray; Andrea Freeman; Peter M Mauch; Kenneth C Anderson; Lee M Nadler; Jerome Ritz
CD6+ T cell-depleted allogeneic bone marrow transplantation for non-Hodgkin's lymphoma.
Bone marrow transplantation 1998;21(12):1177-81.
1998: Arnold S Freedman; John G Gribben; Lee M Nadler
High dose therapy and autologous stem cell transplantation in follicular non-Hodgkin's lymphoma.
Leukemia & lymphoma 1998;28(3-4):219-30.
1998: Arnold S Freedman; Donna Neuberg; John G Gribben; Peter M Mauch; Robert J Soiffer; David C Fisher; Kenneth C Anderson; N Andersen; Robert Schlossman; M Kroon; Jerome Ritz; Jon C Aster; Lee M Nadler
High-dose chemoradiotherapy and anti-B-cell monoclonal antibody-purged autologous bone marrow transplantation in mantle-cell lymphoma: no evidence for long-term remission.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1998;16(1):13-8.
1998: Paolo Ghia; Vassiliki A Boussiotis; Joachim L Schultze; Angelo A Cardoso; D M Dorfman; John G Gribben; Arnold S Freedman; Lee M Nadler
Unbalanced expression of bcl-2 family proteins in follicular lymphoma: contribution of CD40 signaling in promoting survival.
Blood 1998;91(1):244-51.
1997: Arnold S Freedman; Donna Neuberg; Peter M Mauch; John G Gribben; Robert J Soiffer; Kenneth C Anderson; M Robertson; David C Fisher; Robert Schlossman; M Kroon; C Rhuda; C Kuhlman; Jerome Ritz; Lee M Nadler
Cyclophosphamide, doxorubicin, vincristine, prednisone dose intensification with granulocyte colony-stimulating factor markedly depletes stem cell reserve for autologous bone marrow transplantation.
Blood 1997;90(12):4996-5001.
1997: Joachim L Schultze; S Michalak; MJ Seamon; Glenn Dranoff; K Jung; J Daley; Julio C Delgado; John G Gribben; Lee M Nadler
CD40-activated human B cells: an alternative source of highly efficient antigen presenting cells to generate autologous antigen-specific T cells for adoptive immunotherapy.
The Journal of clinical investigation 1997;100(11):2757-65.
1997: David M Dorfman; Joachim L Schultze; Aliakbar Shahsafaei; S Michalak; John G Gribben; Gordon J Freeman; Geraldine S Pinkus; Lee M Nadler
In vivo expression of B7-1 and B7-2 by follicular lymphoma cells can prevent induction of T-cell anergy but is insufficient to induce significant T-cell proliferation.
Blood 1997;90(11):4297-306.
1997: Niels S Andersen; John W Donovan; J S Borus; Christine M Poor; Donna Neuberg; Jon C Aster; Lee M Nadler; Arnold S Freedman; John G Gribben
Failure of immunologic purging in mantle cell lymphoma assessed by polymerase chain reaction detection of minimal residual disease.
Blood 1997;90(10):4212-21.
1997: Claudia Voena; marco ladetto; Monica Astolfi; D Provan; John G Gribben; Mario Boccadoro; Alessandro Pileri; Paolo Corradini
A novel nested-PCR strategy for the detection of rearranged immunoglobulin heavy-chain genes in B cell tumors.
Leukemia 1997;11(10):1793-8.
1997: Vassiliki A Boussiotis; B J Lee; Gordon J Freeman; John G Gribben; Lee M Nadler
Induction of T cell clonal anergy results in resistance, whereas CD28-mediated costimulation primes for susceptibility to Fas- and Bax-mediated programmed cell death.
Journal of immunology (Baltimore, Md. : 1950) 1997;159(7):3156-67.
1997: Angelo A Cardoso; MJ Seamon; H M Afonso; Paolo Ghia; Vassiliki A Boussiotis; Gordon J Freeman; John G Gribben; Stephen E Sallan; Lee M Nadler
Ex vivo generation of human anti-pre-B leukemia-specific autologous cytolytic T cells.
Blood 1997;90(2):549-61.
1997: Joachim L Schultze; MJ Seamon; S Michalak; John G Gribben; Lee M Nadler
Autologous tumor infiltrating T cells cytotoxic for follicular lymphoma cells can be expanded in vitro.
Blood 1997;89(10):3806-16.
1997: John G Gribben; Angelo A Cardoso; Joachim L Schultze; Lee M Nadler
Biologic response modifiers in acute lymphoblastic leukemia.
Leukemia 1997;11 Suppl 4():S31-3.
1997: John G Gribben
Bone marrow transplantation for low-grade B-cell malignancies.
Current opinion in oncology 1997;9(2):117-21.
1997: John G Gribben; Joachim L Schultze
The detection of minimal residual disease: implications for bone marrow transplantation.
Cancer treatment and research 1997;77():99-120.
1996: C D Gimmi; B W Morrison; B A Mainprice; John G Gribben; Vassiliki A Boussiotis; Gordon J Freeman; S Y Park; M Watanabe; J Gong; Daniel F Hayes; Donald Kufe; Lee M Nadler
Breast cancer-associated antigen, DF3/MUC1, induces apoptosis of activated human T cells.
Nature medicine 1996;2(12):1367-70.
1996: C S Zwicky; A B Maddocks; N Andersen; John G Gribben
Eradication of polymerase chain reaction detectable immunoglobulin gene rearrangement in non-Hodgkin's lymphoma is associated with decreased relapse after autologous bone marrow transplantation.
Blood 1996;88(9):3314-22.
1996: Vassiliki A Boussiotis; Gordon J Freeman; John G Gribben; Lee M Nadler
The role of B7-1/B7-2:CD28/CLTA-4 pathways in the prevention of anergy, induction of productive immunity and down-regulation of the immune response.
Immunological reviews 1996;153():5-26.
1996: Arnold S Freedman; John G Gribben; Donna Neuberg; Peter M Mauch; Robert J Soiffer; Kenneth C Anderson; L Pandite; M J Robertson; M Kroon; Jerome Ritz; Lee M Nadler
High-dose therapy and autologous bone marrow transplantation in patients with follicular lymphoma during first remission.
Blood 1996;88(7):2780-6.
1996: D Provan; Lini Bartlett-Pandite; C Zwicky; Donna Neuberg; A Maddocks; Paolo Corradini; Robert J Soiffer; Jerome Ritz; Lee M Nadler; John G Gribben
Eradication of polymerase chain reaction-detectable chronic lymphocytic leukemia cells is associated with improved outcome after bone marrow transplantation.
Blood 1996;88(6):2228-35.
1996: Vassiliki A Boussiotis; Dwayne Barber; B J Lee; John G Gribben; Gordon J Freeman; Lee M Nadler
Differential association of protein tyrosine kinases with the T cell receptor is linked to the induction of anergy and its prevention by B7 family-mediated costimulation.
The Journal of experimental medicine 1996;184(2):365-76.
1996: Angelo A Cardoso; Joachim L Schultze; Vassiliki A Boussiotis; Gordon J Freeman; M J Seamon; S Laszlo; A Billet; Stephen E Sallan; John G Gribben; Lee M Nadler
Pre-B acute lymphoblastic leukemia cells may induce T-cell anergy to alloantigen.
Blood 1996;88(1):41-8.
1996: J Schultze; Lee M Nadler; John G Gribben
B7-mediated costimulation and the immune response.
Blood reviews 1996;10(2):111-27.
1996: John G Gribben; Eva C Guinan; Vassiliki A Boussiotis; X Y Ke; L Linsley; Colin A Sieff; GS Gray; Gordon J Freeman; Lee M Nadler
Complete blockade of B7 family-mediated costimulation is necessary to induce human alloantigen-specific anergy: a method to ameliorate graft-versus-host disease and extend the donor pool.
Blood 1996;87(11):4887-93.
1995: Joachim L Schultze; Angelo A Cardoso; Gordon J Freeman; M J Seamon; J Daley; Geraldine S Pinkus; John G Gribben; Lee M Nadler
Follicular lymphomas can be induced to present alloantigen efficiently: a conceptual model to improve their tumor immunogenicity.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(18):8200-4.
1995: Gordon J Freeman; Vassiliki A Boussiotis; Anukanth Anumanthan; G M Bernstein; X Y Ke; P D Rennert; GS Gray; John G Gribben; Lee M Nadler
B7-1 and B7-2 do not deliver identical costimulatory signals, since B7-2 but not B7-1 preferentially costimulates the initial production of IL-4.
Immunity 1995;2(5):523-32.
1995: Vassiliki A Boussiotis; Gordon J Freeman; John G Gribben; Lee M Nadler
The critical role of CD28 signalling in the prevention of human T-cell anergy.
Research in immunology 1995;146(3):140-9.
1995: John G Gribben; Gordon J Freeman; Vassiliki A Boussiotis; P Rennert; C L Jellis; E Greenfield; M Barber; V A Restivo; X Ke; GS Gray
CTLA4 mediates antigen-specific apoptosis of human T cells.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(3):811-5.
1994: Eva C Guinan; John G Gribben; Vassiliki A Boussiotis; Gordon J Freeman; Lee M Nadler
Pivotal role of the B7:CD28 pathway in transplantation tolerance and tumor immunity.
Blood 1994;84(10):3261-82.
1994: Vassiliki A Boussiotis; Dwayne Barber; T Nakarai; Gordon J Freeman; John G Gribben; G M Bernstein; Alan D D'Andrea; Jerome Ritz; Lee M Nadler
Prevention of T cell anergy by signaling through the gamma c chain of the IL-2 receptor.
Science (New York, N.Y.) 1994;266(5187):1039-42.
1994: Vassiliki A Boussiotis; Gordon J Freeman; James D Griffin; GS Gray; John G Gribben; Lee M Nadler
CD2 is involved in maintenance and reversal of human alloantigen-specific clonal anergy.
The Journal of experimental medicine 1994;180(5):1665-73.
1994: Vassiliki A Boussiotis; John G Gribben; Gordon J Freeman; Lee M Nadler
Blockade of the CD28 co-stimulatory pathway: a means to induce tolerance.
Current opinion in immunology 1994;6(5):797-807.
1994: P Engel; John G Gribben; Gordon J Freeman; L J Zhou; Y Nozawa; M Abe; Lee M Nadler; H Wakasa; Thomas F Tedder
The B7-2 (B70) costimulatory molecule expressed by monocytes and activated B lymphocytes is the CD86 differentiation antigen.
Blood 1994;84(5):1402-7.
1994: John G Gribben; Donna Neuberg; M Barber; J Moore; K W Pesek; Arnold S Freedman; Lee M Nadler
Detection of residual lymphoma cells by polymerase chain reaction in peripheral blood is significantly less predictive for relapse than detection in bone marrow.
Blood 1994;83(12):3800-7.
1994: J M Munro; Arnold S Freedman; Jon C Aster; John G Gribben; N C Lee; K K Rhynhart; Jacques Banchereau; Lee M Nadler
In vivo expression of the B7 costimulatory molecule by subsets of antigen-presenting cells and the malignant cells of Hodgkin's disease.
Blood 1994;83(3):793-8.
1993: Vassiliki A Boussiotis; Gordon J Freeman; John G Gribben; J Daley; G Gray; Lee M Nadler
Activated human B lymphocytes express three CTLA-4 counterreceptors that costimulate T-cell activation.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(23):11059-63.
1993: Gordon J Freeman; F Borriello; Richard J Hodes; H Reiser; John G Gribben; J W Ng; J Kim; John Goldberg; Karen S Hathcock; G Laszlo
Murine B7-2, an alternative CTLA4 counter-receptor that costimulates T cell proliferation and interleukin 2 production.
The Journal of experimental medicine 1993;178(6):2185-92.
1993: C D Gimmi; John G Gribben; Gordon J Freeman; Lee M Nadler
[Failing B7 costimulation engenders a peripheral clonal T-cell anergy in a human antigen-specific model].
Schweizerische medizinische Wochenschrift 1993;123(47):2255-6.
1993: Gordon J Freeman; John G Gribben; Vassiliki A Boussiotis; J W Ng; V A Restivo; L A Lombard; GS Gray; Lee M Nadler
Cloning of B7-2: a CTLA-4 counter-receptor that costimulates human T cell proliferation.
Science (New York, N.Y.) 1993;262(5135):909-11.
1993: Vassiliki A Boussiotis; Gordon J Freeman; G Gray; John G Gribben; Lee M Nadler
B7 but not intercellular adhesion molecule-1 costimulation prevents the induction of human alloantigen-specific tolerance.
The Journal of experimental medicine 1993;178(5):1753-63.
1993: S N Rabinowe; Robert J Soiffer; John G Gribben; H Daley; Arnold S Freedman; J Daley; K Pesek; Donna Neuberg; Geraldine S Pinkus; P R Leavitt
Autologous and allogeneic bone marrow transplantation for poor prognosis patients with B-cell chronic lymphocytic leukemia.
Blood 1993;82(4):1366-76.
1993: C D Gimmi; Gordon J Freeman; John G Gribben; G Gray; Lee M Nadler
Human T-cell clonal anergy is induced by antigen presentation in the absence of B7 costimulation.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(14):6586-90.
1993: John G Gribben; Donna Neuberg; Arnold S Freedman; C D Gimmi; K W Pesek; M Barber; L Saporito; S D Woo; F Coral; N Spector
Detection by polymerase chain reaction of residual cells with the bcl-2 translocation is associated with increased risk of relapse after autologous bone marrow transplantation for B-cell lymphoma.
Blood 1993;81(12):3449-57.
1993: Michael L Grossbard; John G Gribben; Arnold S Freedman; J M Lambert; J Kinsella; S N Rabinowe; L Eliseo; J A Taylor; W A Blättler; C L Epstein
Adjuvant immunotoxin therapy with anti-B4-blocked ricin after autologous bone marrow transplantation for patients with B-cell non-Hodgkin's lymphoma.
Blood 1993;81(9):2263-71.
1993: John G Gribben; Lee M Nadler
Bone marrow purging for autologous bone marrow transplantation.
Leukemia & lymphoma 1993;11 Suppl 2():141-8.
1993: John G Gribben; Lee M Nadler
The immunological treatment of human marrow in vitro in transplantation biology.
Cancer treatment and research 1993;64():189-211.
1992: John G Gribben; L Saporito; M Barber; K W Blake; R M Edwards; James D Griffin; Arnold S Freedman; Lee M Nadler
Bone marrows of non-Hodgkin's lymphoma patients with a bcl-2 translocation can be purged of polymerase chain reaction-detectable lymphoma cells using monoclonal antibodies and immunomagnetic bead depletion.
Blood 1992;80(4):1083-9.
1992: Gordon J Freeman; C M Disteche; John G Gribben; D A Adler; Arnold S Freedman; J Dougery; Lee M Nadler
The gene for B7, a costimulatory signal for T-cell activation, maps to chromosomal region 3q13.3-3q21.
Blood 1992;79(2):489-94.
1991: John G Gribben; Arnold S Freedman; S D Woo; K Blake; R S Shu; Gordon J Freeman; J A Longtine; Geraldine S Pinkus; Lee M Nadler
All advanced stage non-Hodgkin's lymphomas with a polymerase chain reaction amplifiable breakpoint of bcl-2 have residual cells containing the bcl-2 rearrangement at evaluation and after treatment.
Blood 1991;78(12):3275-80.
1991: John G Gribben; Arnold S Freedman; Donna Neuberg; Denis-Claude Roy; K W Blake; S D Woo; Michael L Grossbard; S N Rabinowe; F Coral; Gordon J Freeman
Immunologic purging of marrow assessed by PCR before autologous bone marrow transplantation for B-cell lymphoma.
The New England journal of medicine 1991;325(22):1525-33.
1991: Gordon J Freeman; GS Gray; C D Gimmi; David Lombard; L J Zhou; M White; Joyce Diane Fingeroth; John G Gribben; Lee M Nadler
Structure, expression, and T cell costimulatory activity of the murine homologue of the human B lymphocyte activation antigen B7.
The Journal of experimental medicine 1991;174(3):625-31.
1991: C D Gimmi; Gordon J Freeman; John G Gribben; K Sugita; Arnold S Freedman; C Morimoto; Lee M Nadler
B-cell surface antigen B7 provides a costimulatory signal that induces T cells to proliferate and secrete interleukin 2.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(15):6575-9.
1991: S N Rabinowe; Robert J Soiffer; Nancy J Tarbell; Donna Neuberg; Arnold S Freedman; J Seifter; K W Blake; John G Gribben; Kenneth C Anderson; Tak Takvorian
Hemolytic-uremic syndrome following bone marrow transplantation in adults for hematologic malignancies.
Blood 1991;77(8):1837-44.