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Thomas Gridley

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Jingxia Xu; Thomas Gridley
Notch2 is required in somatic cells for breakdown of ovarian germ-cell nests and formation of primordial follicles.
Luke T Krebs; Christine R Norton; Kathleen F Oram; Christa Starling; Jingxia Xu; Michael J Bevan; Cara K Bradley; ML Deftos; Thomas Gridley
The Notch-regulated ankyrin repeat protein is required for proper anterior-posterior somite patterning in mice.
Jingxia Xu; Thomas Gridley
Notch Signaling during Oogenesis in Drosophila melanogaster.

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All Publications

2013: Jingxia Xu; Thomas Gridley
Notch2 is required in somatic cells for breakdown of ovarian germ-cell nests and formation of primordial follicles.
BMC biology 2013;11():13.
2012: Luke T Krebs; Christine R Norton; Kathleen F Oram; Christa Starling; Jingxia Xu; Michael J Bevan; Cara K Bradley; ML Deftos; Thomas Gridley
The Notch-regulated ankyrin repeat protein is required for proper anterior-posterior somite patterning in mice.
Genesis (New York, N.Y. : 2000) 2012;50(4):366-74.
2012: Jingxia Xu; Thomas Gridley
Notch Signaling during Oogenesis in Drosophila melanogaster.
Genetics research international 2012;2012():648207.
2012: Joshua Boucher; Thomas Gridley; Lucy Liaw
Molecular pathways of notch signaling in vascular smooth muscle cells.
Frontiers in physiology 2012;3():81.
2010: Xuesong Feng; Luke T Krebs; Thomas Gridley
Patent ductus arteriosus in mice with smooth muscle-specific Jag1 deletion.
Development (Cambridge, England) 2010;137(24):4191-9.
2010: Jingxia Xu; Luke T Krebs; Thomas Gridley
Generation of mice with a conditional null allele of the Jagged2 gene.
Genesis (New York, N.Y. : 2000) 2010;48(6):390-3.
2010: Luke T Krebs; Christa Starling; Alexander V Chervonsky; Thomas Gridley
Notch1 activation in mice causes arteriovenous malformations phenocopied by ephrinB2 and EphB4 mutants.
Genesis (New York, N.Y. : 2000) 2010;48(3):146-50.
2009: Hilda Lomelí; Christa Starling; Thomas Gridley
Epiblast-specific Snai1 deletion results in embryonic lethality due to multiple vascular defects.
BMC research notes 2009;2():22.
2008: Julie Lozier; Brent McCright; Thomas Gridley
Notch signaling regulates bile duct morphogenesis in mice.
PloS one 2008;3(3):e1851.
2007: Amy E Kiernan; Renhua Li; Norman L Hawes; Gary Churchill; Thomas Gridley
Genetic background modifies inner ear and eye phenotypes of jag1 heterozygous mice.
Genetics 2007;177(1):307-11.
2007: Thomas Gridley
Notch signaling in vascular development and physiology.
Development (Cambridge, England) 2007;134(15):2709-18.
2007: Derk Amsen; Andrey Antov; Dragana Jankovic; Alan Sher; Freddy Radtke; Abdallah Souabni; Meinrad Busslinger; Brent McCright; Thomas Gridley; Richard A Flavell
Direct regulation of Gata3 expression determines the T helper differentiation potential of Notch.
Immunity 2007;27(1):89-99.
2007: Stephen A Murray; Kathleen F Oram; Thomas Gridley
Multiple functions of Snail family genes during palate development in mice.
Development (Cambridge, England) 2007;134(9):1789-97.
2007: Marie Monet; Valérie Domenga; Barbara Lemaire; Céline Souilhol; Francina Langa; Charles Babinet; Thomas Gridley; Elisabeth Tournier-Lasserve; Michel Cohen-Tannoudji; Anne Joutel
The archetypal R90C CADASIL-NOTCH3 mutation retains NOTCH3 function in vivo.
Human molecular genetics 2007;16(8):982-92.
2007: Gareth R Howell; Mami Shindo; Stephen A Murray; Thomas Gridley; Lawriston A Wilson; John C Schimenti
Mutation of a ubiquitously expressed mouse transmembrane protein (Tapt1) causes specific skeletal homeotic transformations.
Genetics 2007;175(2):699-707.
2006: Stephen A Murray; Thomas Gridley
Snail1 gene function during early embryo patterning in mice.
Cell cycle (Georgetown, Tex.) 2006;5(22):2566-70.
2006: Thomas Gridley
The long and short of it: somite formation in mice.
Developmental dynamics : an official publication of the American Association of Anatomists 2006;235(9):2330-6.
2006: Stephen A Murray; Thomas Gridley
Snail family genes are required for left-right asymmetry determination, but not neural crest formation, in mice.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(27):10300-4.
2006: Jingxia Xu; Christine R Norton; Thomas Gridley
Not all lunatic fringe null female mice are infertile.
Development (Cambridge, England) 2006;133(4):579; author reply 579-80.
2006: Amy E Kiernan; Jingxia Xu; Thomas Gridley
The Notch ligand JAG1 is required for sensory progenitor development in the mammalian inner ear.
PLoS genetics 2006;2(1):e4.
2006: Brent McCright; Julie Lozier; Thomas Gridley
Generation of new Notch2 mutant alleles.
Genesis (New York, N.Y. : 2000) 2006;44(1):29-33.
2006: Stephen A Murray; Ethan Carver; Thomas Gridley
Generation of a Snail1 (Snai1) conditional null allele.
Genesis (New York, N.Y. : 2000) 2006;44(1):7-11.
2005: Amy E Kiernan; Ralf Cordes; Raphael Kopan; Achim Gossler; Thomas Gridley
The Notch ligands DLL1 and JAG2 act synergistically to regulate hair cell development in the mammalian inner ear.
Development (Cambridge, England) 2005;132(19):4353-62.
2005: Kathleen F Oram; Thomas Gridley
Mutations in snail family genes enhance craniosynostosis of Twist1 haplo-insufficient mice: implications for Saethre-Chotzen Syndrome.
Genetics 2005;170(2):971-4.
2005: Pierre Savagner; Donna F Kusewitt; Ethan Carver; Fabrice Magnino; Chagsun Choi; Thomas Gridley; Laurie G Hudson
Developmental transcription factor slug is required for effective re-epithelialization by adult keratinocytes.
Journal of cellular physiology 2005;202(3):858-66.
2004: Valérie Domenga; Peggy Fardoux; Pierre Lacombe; Marie Monet; Jacqueline Maciazek; Luke T Krebs; Bernard Klonjkowski; Eliane Berrou; Mathias Mericskay; Zhen Li; Elisabeth Tournier-Lasserve; Thomas Gridley; Anne Joutel
Notch3 is required for arterial identity and maturation of vascular smooth muscle cells.
Genes & development 2004;18(22):2730-5.
2004: Thomas Gridley
Kick it up a Notch: NOTCH1 activation in T-ALL.
Cancer cell 2004;6(5):431-2.
2004: Luke T Krebs; John R Shutter; Kenji Tanigaki; Tasuku Honjo; Kevin L Stark; Thomas Gridley
Haploinsufficient lethality and formation of arteriovenous malformations in Notch pathway mutants.
Genes & development 2004;18(20):2469-73.
2003: Luke T Krebs; Yingzi Xue; Christine R Norton; John P Sundberg; Paul Beatus; Urban Lendahl; Anne Joutel; Thomas Gridley
Characterization of Notch3-deficient mice: normal embryonic development and absence of genetic interactions with a Notch1 mutation.
Genesis (New York, N.Y. : 2000) 2003;37(3):139-43.
2003: Luke T Krebs; Naomi Iwai; Shigenori Nonaka; Ian Welsh; Yu Lan; Rulang Jiang; Yukio Saijoh; Timothy P O'Brien; Hiroshi Hamada; Thomas Gridley
Notch signaling regulates left-right asymmetry determination by inducing Nodal expression.
Genes & development 2003;17(10):1207-12.
2003: Thomas Gridley
Notch signaling and inherited disease syndromes.
Human molecular genetics 2003;12 Spec No 1():R9-13.
2003: Kathleen F Oram; Ethan Carver; Thomas Gridley
Slug expression during organogenesis in mice.
The anatomical record. Part A, Discoveries in molecular, cellular, and evolutionary biology 2003;271(1):189-91.
2002: Ethan Carver; Kathleen F Oram; Thomas Gridley
Craniosynostosis in Twist heterozygous mice: a model for Saethre-Chotzen syndrome.
The Anatomical record 2002;268(2):90-2.
2002: Nian Zhang; Christine R Norton; Thomas Gridley
Segmentation defects of Notch pathway mutants and absence of a synergistic phenotype in lunatic fringe/radical fringe double mutant mice.
Genesis (New York, N.Y. : 2000) 2002;33(1):21-8.
2002: Brent McCright; Julie Lozier; Thomas Gridley
A mouse model of Alagille syndrome: Notch2 as a genetic modifier of Jag1 haploinsufficiency.
Development (Cambridge, England) 2002;129(4):1075-82.
2001: Ethan Carver; R Jiang; Y Lan; Kathleen F Oram; Thomas Gridley
The mouse snail gene encodes a key regulator of the epithelial-mesenchymal transition.
Molecular and cellular biology 2001;21(23):8184-8.
2001: Luke T Krebs; ML Deftos; Michael J Bevan; Thomas Gridley
The Nrarp gene encodes an ankyrin-repeat protein that is transcriptionally regulated by the notch signaling pathway.
Developmental biology 2001;238(1):110-9.
2001: Akihiro Ikeda; Sakae Ikeda; Thomas Gridley; Patsy M Nishina; Jürgen K Naggert
Neural tube defects and neuroepithelial cell death in Tulp3 knockout mice.
Human molecular genetics 2001;10(12):1325-34.
2001: Thomas Gridley
Notch signaling during vascular development.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(10):5377-8.
2001: Brent McCright; X Gao; L Shen; Julie Lozier; Y Lan; M Maguire; D Herzlinger; Gerry Weinmaster; Rulang Jiang; Thomas Gridley
Defects in development of the kidney, heart and eye vasculature in mice homozygous for a hypomorphic Notch2 mutation.
Development (Cambridge, England) 2001;128(4):491-502.
2000: Pamela J Lanford; R Shailam; C R Norton; Thomas Gridley; Matthew W Kelley
Expression of Math1 and HES5 in the cochleae of wildtype and Jag2 mutant mice.
Journal of the Association for Research in Otolaryngology : JARO 2000;1(2):161-71.
2000: N Zhang; John P Sundberg; Thomas Gridley
Mice mutant for Ppap2c, a homolog of the germ cell migration regulator wunen, are viable and fertile.
Genesis (New York, N.Y. : 2000) 2000;27(4):137-40.
2000: N Zhang; G V Martin; Matthew W Kelley; Thomas Gridley
A mutation in the Lunatic fringe gene suppresses the effects of a Jagged2 mutation on inner hair cell development in the cochlea.
Current biology : CB 2000;10(11):659-62.
2000: Luke T Krebs; Yingzi Xue; Christine R Norton; John R Shutter; M Maguire; John P Sundberg; D Gallahan; V Closson; Jan Kitajewski; Robert Callahan; Gilbert H Smith; Kevin L Stark; Thomas Gridley
Notch signaling is essential for vascular morphogenesis in mice.
Genes & development 2000;14(11):1343-52.
2000: N Zhang; N G Copeland; D J Gilbert; N A Jenkins; Thomas Gridley
Cloning, expression, and chromosomal localization of a mouse gene homologous to the germ cell migration regulator wunen and to type 2 phosphatidic acid phosphatases.
Genomics 2000;63(1):142-4.
1999: R Shailam; Pamela J Lanford; C M Dolinsky; C R Norton; Thomas Gridley; Matthew W Kelley
Expression of proneural and neurogenic genes in the embryonic mammalian vestibular system.
Journal of neurocytology 1999;28(10-11):809-19.
1999: Yingzi Xue; X Gao; C E Lindsell; Christine R Norton; Bo Chang; C Hicks; M Gendron-Maguire; Elizabeth B Rand; Gerry Weinmaster; Thomas Gridley
Embryonic lethality and vascular defects in mice lacking the Notch ligand Jagged1.
Human molecular genetics 1999;8(5):723-30.
1999: R Bhatia-Gaur; A A Donjacour; PJ Sciavolino; M Kim; N Desai; P Young; C R Norton; Thomas Gridley; Robert Cardiff; G R Cunha; Cory Abate-Shen; Michael M Shen
Roles for Nkx3.1 in prostate development and cancer.
Genes & development 1999;13(8):966-77.
1999: Pamela J Lanford; Y Lan; R Jiang; C Lindsell; Gerry Weinmaster; Thomas Gridley; Matthew W Kelley
Notch signalling pathway mediates hair cell development in mammalian cochlea.
Nature genetics 1999;21(3):289-92.
1998: R Jiang; Christine R Norton; N G Copeland; D J Gilbert; N A Jenkins; Thomas Gridley
Genomic organization, expression and chromosomal localization of the mouse Slug (Slugh) gene.
Biochimica et biophysica acta 1998;1443(1-2):251-4.
1998: S M Bell; Y Lan; Rulang Jiang; Thomas Gridley
Exclusion of Jagged2 as a candidate for the legless gene.
Mammalian genome : official journal of the International Mammalian Genome Society 1998;9(9):778-9.
1998: N Zhang; Thomas Gridley
Defects in somite formation in lunatic fringe-deficient mice.
Nature 1998;394(6691):374-7.
1998: Rulang Jiang; Y Lan; C R Norton; J P Sundberg; Thomas Gridley
The Slug gene is not essential for mesoderm or neural crest development in mice.
Developmental biology 1998;198(2):277-85.
1998: X Gao; N G Copeland; D J Gilbert; N A Jenkins; Thomas Gridley
Assignment of the murine Notch2 and Notch3 genes to chromosomes 3 and 17.
Genomics 1998;49(1):160-1.
1998: Rulang Jiang; Yu Lan; Harold D Chapman; Carrie Shawber; Christine R Norton; D V Serreze; Gerry Weinmaster; Thomas Gridley
Defects in limb, craniofacial, and thymic development in Jagged2 mutant mice.
Genes & development 1998;12(7):1046-57.
1997: Rulang Jiang; N G Copeland; D J Gilbert; N A Jenkins; Thomas Gridley
Genomic organization and chromosomal localization of the mouse snail (Sna) gene.
Mammalian genome : official journal of the International Mammalian Genome Society 1997;8(9):686-8.
1997: Rulang Jiang; Thomas Gridley
Gene targeting: things go better with Cre.
Current biology : CB 1997;7(5):R321-3.
1997: Yu Lan; Rulang Jiang; Carrie Shawber; Gerry Weinmaster; Thomas Gridley
The Jagged2 gene maps to chromosome 12 and is a candidate for the lgl and sm mutations.
Mammalian genome : official journal of the International Mammalian Genome Society 1997;8(11):875-6.
1997: Thomas Gridley
Notch signaling in vertebrate development and disease.
Molecular and cellular neurosciences 1997;9(2):103-8.
1996: M Mallo; Thomas Gridley
Development of the mammalian ear: coordinate regulation of formation of the tympanic ring and the external acoustic meatus.
Development (Cambridge, England) 1996;122(1):173-9.
1995: M Mallo; M Gendron-Maguire; M L Harbison; Thomas Gridley
Protein characterization and targeted disruption of Grg, a mouse gene related to the groucho transcript of the Drosophila Enhancer of split complex.
Developmental dynamics : an official publication of the American Association of Anatomists 1995;204(3):338-47.
1995: JA Rivera-Pérez; M Mallo; M Gendron-Maguire; Thomas Gridley; Richard R Behringer
Goosecoid is not an essential component of the mouse gastrula organizer but is required for craniofacial and rib development.
Development (Cambridge, England) 1995;121(9):3005-12.
1995: T N Sato; Y Tozawa; U Deutsch; K Wolburg-Buchholz; Y Fujiwara; M Gendron-Maguire; Thomas Gridley; H Wolburg; W Risau; Y Qin
Distinct roles of the receptor tyrosine kinases Tie-1 and Tie-2 in blood vessel formation.
Nature 1995;376(6535):70-4.
1995: M Mallo; P M Lieberman; Thomas Gridley
Possible involvement of the mouse Grg protein in transcription.
Cellular & molecular biology research 1995;41(5):435-40.
1994: M Zhang; H J Kim; H Marshall; M Gendron-Maguire; D A Lucas; A Baron; L J Gudas; Thomas Gridley; R Krumlauf; J F Grippo
Ectopic Hoxa-1 induces rhombomere transformation in mouse hindbrain.
Development (Cambridge, England) 1994;120(9):2431-42.
1994: H Schrewe; M Gendron-Maguire; M L Harbison; Thomas Gridley
Mice homozygous for a null mutation of activin beta B are viable and fertile.
Mechanisms of development 1994;47(1):43-51.
1994: M Mallo; E Steingrímsson; N G Copeland; N A Jenkins; Thomas Gridley
Genomic organization, alternative polyadenylation, and chromosomal localization of Grg, a mouse gene related to the groucho transcript of the Drosophila Enhancer of split complex.
Genomics 1994;21(1):194-201.
1994: P J Swiatek; C E Lindsell; F F del Amo; Gerry Weinmaster; Thomas Gridley
Notch1 is essential for postimplantation development in mice.
Genes & development 1994;8(6):707-19.
1993: M Gendron-Maguire; M Mallo; M Zhang; Thomas Gridley
Hoxa-2 mutant mice exhibit homeotic transformation of skeletal elements derived from cranial neural crest.
Cell 1993;75(7):1317-31.
1993: P J Swiatek; Thomas Gridley
Perinatal lethality and defects in hindbrain development in mice homozygous for a targeted mutation of the zinc finger gene Krox20.
Genes & development 1993;7(11):2071-84.
1993: M Mallo; F Franco del Amo; Thomas Gridley
Cloning and developmental expression of Grg, a mouse gene related to the groucho transcript of the Drosophila Enhancer of split complex.
Mechanisms of development 1993;42(1-2):67-76.
1993: F F del Amo; M Gendron-Maguire; P J Swiatek; N A Jenkins; N G Copeland; Thomas Gridley
Cloning, analysis, and chromosomal localization of Notch-1, a mouse homolog of Drosophila Notch.
Genomics 1993;15(2):259-64.
1993: F Franco del Amo; M Gendron-Maguire; P J Swiatek; Thomas Gridley
Cloning, sequencing and expression of the mouse mammalian achaete-scute homolog 1 (MASH1).
Biochimica et biophysica acta 1993;1171(3):323-7.
1993: M Gendron-Maguire; Thomas Gridley
Identification of transgenic mice.
Methods in enzymology 1993;225():794-9.
1992: D E Smith; F Franco del Amo; Thomas Gridley
Isolation of Sna, a mouse gene homologous to the Drosophila genes snail and escargot: its expression pattern suggests multiple roles during postimplantation development.
Development (Cambridge, England) 1992;116(4):1033-9.
1992: D E Smith; Thomas Gridley
Differential screening of a PCR-generated mouse embryo cDNA library: glucose transporters are differentially expressed in early postimplantation mouse embryos.
Development (Cambridge, England) 1992;116(3):555-61.
1992: F F Del Amo; D E Smith; P J Swiatek; M Gendron-Maguire; Ralph J Greenspan; Andrew P McMahon; Thomas Gridley
Expression pattern of Motch, a mouse homolog of Drosophila Notch, suggests an important role in early postimplantation mouse development.
Development (Cambridge, England) 1992;115(3):737-44.
1991: Thomas Gridley; Rudolf Jaenisch; M Gendron-Maguire
The murine Mov-34 gene: full-length cDNA and genomic organization.
Genomics 1991;11(3):501-7.
1991: Thomas Gridley
Insertional versus targeted mutagenesis in mice.
The New biologist 1991;3(11):1025-34.