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Christian Griesinger

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Elias Akoury; Jacek Biernat; Michal Gajda; Christian Griesinger; Eckhard Mandelkow; Marcus Pickhardt; Pornsuwan Soraya; Markus Zweckstetter
Inhibition of tau filament formation by conformational modulation.
Manuel Schmidt; Han Sun; Christian Griesinger; Andrei Leonov; Uwe M Reinscheid
Chiral discrimination of amines by anisotropic NMR parameters using chiral polyacrylamide-based gels.
Ariel A Valiente-Gabioud; Andrés Binolfi; Christian Griesinger; Laura Molina-Rubino; Valentina Torres-Monserrat; Claudio O Fernández
Structural basis behind the interaction of Zn²⁺ with the protein α-synuclein and the Aβ peptide: a comparative analysis.

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2013: Elias Akoury; Jacek Biernat; Michal Gajda; Christian Griesinger; Eckhard Mandelkow; Marcus Pickhardt; Pornsuwan Soraya; Markus Zweckstetter
Inhibition of tau filament formation by conformational modulation.
Journal of the American Chemical Society 2013;135(7):2853-62.
2012: Manuel Schmidt; Han Sun; Christian Griesinger; Andrei Leonov; Uwe M Reinscheid
Chiral discrimination of amines by anisotropic NMR parameters using chiral polyacrylamide-based gels.
Magnetic resonance in chemistry : MRC 2012;50 Suppl 1():S38-44.
2012: Ariel A Valiente-Gabioud; Andrés Binolfi; Christian Griesinger; Laura Molina-Rubino; Valentina Torres-Monserrat; Claudio O Fernández
Structural basis behind the interaction of Zn²⁺ with the protein α-synuclein and the Aβ peptide: a comparative analysis.
Journal of inorganic biochemistry 2012;117():334-41.
2012: Ulrich Zachariae; Markus Zweckstetter; Elke Maier; Robert Schneider; Stefan Becker; Roland Benz; Rodolfo Briones; Bert L de Groot; Jean-Philippe Demers; Zrinka Gattin; Karin Giller; Christian Griesinger; Adam Lange
β-Barrel mobility underlies closure of the voltage-dependent anion channel.
Structure (London, England : 1993) 2012;20(9):1540-9.
2012: Venita Daebel; Christian Griesinger; Birgit Habenstein; Elias Akoury; Marc Baldus; Jacek Biernat; Subashchandrabose Chinnathambi; Antoine Loquet; Eckhard Mandelkow; Henrik Müller; Martin Schwalbe; Katharina Tepper; Vinesh Vijayan; Markus Zweckstetter; Adam Lange
β-Sheet core of tau paired helical filaments revealed by solid-state NMR.
Journal of the American Chemical Society 2012;134(34):13982-9.
2012: Robert Berger; Jacques Courtieu; Roberto R Gil; Christian Griesinger; Matthias Köck; Philippe Lesot; Burkhard Luy; Denis Merlet; Armando Navarro-Vázquez; Michael Reggelin; Uwe M Reinscheid; Christina M Thiele; Markus Zweckstetter
Is enantiomer assignment possible by NMR spectroscopy using residual dipolar couplings from chiral nonracemic alignment media?--A critical assessment.
Angewandte Chemie (International ed. in English) 2012;51(33):8388-91.
2012: David Ban; Stefan Becker; Karin Giller; Alvar D Gossert; Christian Griesinger; Donghan Lee
Exceeding the limit of dynamics studies on biomolecules using high spin-lock field strengths with a cryogenically cooled probehead.
Journal of magnetic resonance (San Diego, Calif. : 1997) 2012;221():1-4.
2012: Antoine Loquet; Dietmar Riedel; Nikolaos G Sgourakis; David Baker; Stefan Becker; Karin Giller; Christian Goosmann; Christian Griesinger; Rashmi Gupta; Michael Kolbe; Adam Lange
Atomic model of the type III secretion system needle.
Nature 2012;486(7402):276-9.
2012: T Michael Sabo; Korvin F A Walter; Robert L McFeeters; Davood Bakhtiari; Stefan Becker; Karin Giller; Christian Griesinger; Donghan Lee
Thermal coefficients of the methyl groups within ubiquitin.
Protein science : a publication of the Protein Society 2012;21(4):562-70.
2012: Valerie S Honndorf; Stefan Laufer; Stefan Becker; Nicolas Coudevylle; Christian Griesinger; Michael Habeck
Inferential NMR/X-ray-based structure determination of a dibenzo[a,d]cycloheptenone inhibitor-p38α MAP kinase complex in solution.
Angewandte Chemie (International ed. in English) 2012;51(10):2359-62.
2012: Manuel Schmidt; Gerhard K E Scriba; Han Sun; Christian Griesinger; Lars T Kuhn; Per Rogne; Uwe M Reinscheid
Determining the absolute configuration of (+)-mefloquine HCl, the side-effect-reducing enantiomer of the antimalaria drug Lariam.
Journal of the American Chemical Society 2012;134(6):3080-3.
2012: Julien Orts; Stefan Bartoschek; Christian Griesinger; Peter Monecke; Teresa Carlomagno
An NMR-based scoring function improves the accuracy of binding pose predictions by docking by two orders of magnitude.
Journal of biomolecular NMR 2012;52(1):23-30.
2011: David Ban; Stefan Becker; Bert L de Groot; Dalia Egger; R Bryn Fenwick; Michael Funk; Karin Giller; Helmut Grubmüller; Rudolf Gulich; Reiner Kree; Nils A Lakomek; oliver lange; Donghan Lee; Alois Loidl; Peter Lunkenheimer; Fabio Pichierri; T Michael Sabo; Xavier Salvatella; Korvin F A Walter; Martin Wolf; Christian Griesinger
Kinetics of conformational sampling in ubiquitin.
Angewandte Chemie (International ed. in English) 2011;50(48):11437-40.
2011: Stefan Bibow; Jacek Biernat; Subashchandrabose Chinnathambi; Christian Griesinger; Eckhard Mandelkow; Marco D Mukrasch; Markus Zweckstetter
The dynamic structure of filamentous tau.
Angewandte Chemie (International ed. in English) 2011;50(48):11520-4.
2011: Fabian Peters; Stefan Becker; Rolf Boelens; Lidija Kovačič; Andrei Leonov; Mitcheell Maestre-Martinez; Christian Griesinger
Cys-Ph-TAHA: a lanthanide binding tag for RDC and PCS enhanced protein NMR.
Journal of biomolecular NMR 2011;51(3):329-37.
2011: Han Sun; Emily L Whitson; Edward J d'Auvergne; Chris M Ireland; Armando Navarro-Vázquez; Uwe M Reinscheid; Christian Griesinger
Challenge of large-scale motion for residual dipolar coupling based analysis of configuration: the case of fibrosterol sulfate A.
Journal of the American Chemical Society 2011;133(37):14629-36.
2011: Gonzalo R Lamberto; Xavier Salvatella; Valentina Torres-Monserrat; Markus Zweckstetter; CARLOS WALTER BERTONCINI; Christian Griesinger; Claudio O Fernández
Toward the discovery of effective polycyclic inhibitors of alpha-synuclein amyloid assembly.
The Journal of biological chemistry 2011;286(37):32036-44.
2011: R Bryn Fenwick; Christian Griesinger; Nils A Lakomek; Donghan Lee; Dragomir Milovanovic; Barbara Richter; Stefan Becker; Santi Esteban-Martín; Korvin F A Walter; Xavier Salvatella
Weak long-range correlated motions in a surface patch of ubiquitin involved in molecular recognition.
Journal of the American Chemical Society 2011;133(27):10336-9.
2011: Irina Karyagina; Dietmar Riedel; Stefan Becker; Karin Giller; Christian Griesinger; Thomas M Jovin; Marina Bennati
Electron paramagnetic resonance spectroscopy measures the distance between the external β-strands of folded α-synuclein in amyloid fibrils.
Biophysical journal 2011;101(1):L1-3.
2011: Han Sun; Edward J d'Auvergne; Uwe M Reinscheid; Luiz Carlos Dias; Carlos Kleber Z Andrade; Rafael Oliveira Rocha; Christian Griesinger
Bijvoet in solution reveals unexpected stereoselectivity in a Michael addition.
Chemistry (Weinheim an der Bergstrasse, Germany) 2011;17(6):1811-7.
2011: Andrés Binolfi; Rosario Duran; Christian Griesinger; Ariel A Valiente-Gabioud; Markus Zweckstetter; Claudio O Fernandez
Exploring the structural details of Cu(I) binding to α-synuclein by NMR spectroscopy.
Journal of the American Chemical Society 2011;133(2):194-6.
2011: Madhu Babu Gajula Balija; Christian Griesinger; Alf Herzig; Markus Zweckstetter; Herbert Jäckle
Pre-fibrillar α-synuclein mutants cause Parkinson's disease-like non-motor symptoms in Drosophila.
PloS one 2011;6(9):e24701.
2010: Saskia Villinger; Rodolfo Briones; Karin Giller; Ulrich Zachariae; Adam Lange; Bert L de Groot; Christian Griesinger; Stefan Becker; Markus Zweckstetter
Functional dynamics in the voltage-dependent anion channel.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(52):22546-51.
2010: Andrés Binolfi; Esaú E Rodriguez; Daniela Valensin; Nicola D'Amelio; Emiliano Ippoliti; Gonzalo Obal; Rosario Duran; Alessandra Magistrato; Otto Pritsch; Markus Zweckstetter; Gianni Valensin; Paolo Carloni; Liliana Quintanar; Christian Griesinger; Claudio O Fernández
Bioinorganic chemistry of Parkinson's disease: structural determinants for the copper-mediated amyloid formation of alpha-synuclein.
Inorganic chemistry 2010;49(22):10668-79.
2010: Sebastian Himmel; Sebastian Wolff; Stefan Becker; Donghan Lee; Christian Griesinger
Detection and identification of protein-phosphorylation sites in histidines through HNP correlation patterns.
Angewandte Chemie (International ed. in English) 2010;49(47):8971-4.
2010: Ashutosh Kumar; Henrike Heise; Marcel J J Blommers; Philipp Krastel; Esther Schmitt; Frank Petersen; Siva Jeganathan; Eva-Maria Mandelkow; Teresa Carlomagno; Christian Griesinger; Marc Baldus
Interaction of epothilone B (patupilone) with microtubules as detected by two-dimensional solid-state NMR spectroscopy.
Angewandte Chemie (International ed. in English) 2010;49(41):7504-7.
2010: Xavier Dervillez; Volker Klaukien; Ralf Dürr; Joachim Koch; Alexandra Kreutz; Thomas Haarmann; Michaela Stoll; Donghan Lee; Teresa Carlomagno; Barbara S Schnierle; Kalle Möbius; Christoph Königs; Christian Griesinger; Ursula Dietrich
Peptide ligands selected with CD4-induced epitopes on native dualtropic HIV-1 envelope proteins mimic extracellular coreceptor domains and bind to HIV-1 gp120 independently of coreceptor usage.
Journal of virology 2010;84(19):10131-8.
2010: Patrick Scheu; Ok Bin Kim; Christian Griesinger; Gottfried Unden
Sensing by the membrane-bound sensor kinase DcuS: exogenous versus endogenous sensing of C(4)-dicarboxylates in bacteria.
Future microbiology 2010;5(9):1383-402.
2010: Fernando Rodríguez-Castañeda; Nicolas Coudevylle; Stefan Becker; Nils Brose; Teresa Carlomagno; Christian Griesinger
1H, 13C and 15N resonance assignments of the Calmodulin-Munc13-1 peptide complex.
Biomolecular NMR assignments 2010;4(1):45-8.
2010: Robert Schneider; Manuel Etzkorn; Karin Giller; Venita Daebel; Jörg Eisfeld; Markus Zweckstetter; Christian Griesinger; Stefan Becker; Adam Lange
The native conformation of the human VDAC1 N terminus.
Angewandte Chemie (International ed. in English) 2010;49(10):1882-5.
2010: Fernando Rodríguez-Castañeda; Mitcheell Maestre-Martínez; Nicolas Coudevylle; Kalina Dimova; Harald Junge; Noa Lipstein; Donghan Lee; Stefan Becker; Nils Brose; Olaf Jahn; Teresa Carlomagno; Christian Griesinger
Modular architecture of Munc13/calmodulin complexes: dual regulation by Ca2+ and possible function in short-term synaptic plasticity.
The EMBO journal 2010;29(3):680-91.
2009: Gonzalo R Lamberto; Andrés Binolfi; María L Orcellet; CARLOS WALTER BERTONCINI; Markus Zweckstetter; Christian Griesinger; Claudio O Fernández
Structural and mechanistic basis behind the inhibitory interaction of PcTS on alpha-synuclein amyloid fibril formation.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(50):21057-62.
2009: Marcel Reese; Maria-Teresa Türke; Igor Tkach; Giacomo Parigi; Claudio Luchinat; Thorsten Marquardsen; Andreas Tavernier; Peter Höfer; Frank Engelke; Christian Griesinger; Marina Bennati
(1)H and (13)C dynamic nuclear polarization in aqueous solution with a two-field (0.35 T/14 T) shuttle DNP spectrometer.
Journal of the American Chemical Society 2009;131(42):15086-7.
2009: Daniela Fischer; Marco D Mukrasch; Jacek Biernat; Stefan Bibow; Martin Blackledge; Christian Griesinger; Eckhard Mandelkow; Markus Zweckstetter
Conformational changes specific for pseudophosphorylation at serine 262 selectively impair binding of tau to microtubules.
Biochemistry 2009;48(42):10047-55.
2009: Damla Pinar Karpinar; Madhu Babu Gajula Balija; Sebastian Kügler; Felipe Opazo; Nasrollah Rezaei-Ghaleh; Nora Wender; Hai-Young Kim; Grit Taschenberger; Björn H Falkenburger; Henrike Heise; Ashutosh Kumar; Dietmar Riedel; Lars Fichtner; Aaron Voigt; Gerhard H Braus; Karin Giller; Stefan Becker; Alf Herzig; Marc Baldus; Herbert Jäckle; Stefan Eimer; Jörg B Schulz; Christian Griesinger; Markus Zweckstetter
Pre-fibrillar alpha-synuclein variants with impaired beta-structure increase neurotoxicity in Parkinson's disease models.
The EMBO journal 2009;28(20):3256-68.
2009: Malene Ringkjøbing Jensen; Phineus R L Markwick; Sebastian Meier; Christian Griesinger; Markus Zweckstetter; Stephan Grzesiek; Pau Bernadó; Martin Blackledge
Quantitative determination of the conformational properties of partially folded and intrinsically disordered proteins using NMR dipolar couplings.
Structure (London, England : 1993) 2009;17(9):1169-85.
2009: Christophe Farès; Nils A Lakomek; Korvin F A Walter; Benedikt T C Frank; Jens Meiler; Stefan Becker; Christian Griesinger
Accessing ns-micros side chain dynamics in ubiquitin with methyl RDCs.
Journal of biomolecular NMR 2009;45(1-2):23-44.
2009: Marco D Mukrasch; Stefan Bibow; Jegannath Korukottu; Sadasivam Jeganathan; Jacek Biernat; Christian Griesinger; Eckhard Mandelkow; Markus Zweckstetter
Structural polymorphism of 441-residue tau at single residue resolution.
PLoS biology 2009;7(2):e34.
2009: Víctor M Sánchez-Pedregal; Christian Griesinger
The Tubulin Binding Mode of MT Stabilizing and Destabilizing Agents Studied by NMR.
Topics in current chemistry 2009;286():151-208.
2008: Nils-Alexander Lakomek; oliver lange; Korvin F A Walter; Christophe Farès; Dalia Egger; Peter Lunkenheimer; Jens Meiler; Helmut Grubmüller; Stefan Becker; Bert L de Groot; Christian Griesinger
Residual dipolar couplings as a tool to study molecular recognition of ubiquitin.
Biochemical Society transactions 2008;36(Pt 6):1433-7.
2008: Donghan Lee; Korvin F A Walter; Ann-Kathrin Brückner; Christian Hilty; Stefan Becker; Christian Griesinger
Bilayer in small bicelles revealed by lipid-protein interactions using NMR spectroscopy.
Journal of the American Chemical Society 2008;130(42):13822-3.
2008: Alice Soragni; Barbara Zambelli; Marco D Mukrasch; Jacek Biernat; Sadasivam Jeganathan; Christian Griesinger; Stefano Ciurli; Eckhard Mandelkow; Markus Zweckstetter
Structural characterization of binding of Cu(II) to tau protein.
Biochemistry 2008;47(41):10841-51.
2008: Monika Bayrhuber; Thomas Meins; Michael Habeck; Stefan Becker; Karin Giller; Saskia Villinger; Clemens Vonrhein; Christian Griesinger; Markus Zweckstetter; Kornelius Zeth
Structure of the human voltage-dependent anion channel.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(40):15370-5.
2008: Manuel Etzkorn; Holger Kneuper; Pia Dünnwald; Vinesh Vijayan; Jens Krämer; Christian Griesinger; Stefan Becker; Gottfried Unden; Marc Baldus
Plasticity of the PAS domain and a potential role for signal transduction in the histidine kinase DcuS.
Nature structural & molecular biology 2008;15(10):1031-9.
2008: Andrés Binolfi; Gonzalo R Lamberto; Rosario Duran; Liliana Quintanar; CARLOS WALTER BERTONCINI; Jose M Souza; Carlos Cerveñansky; Markus Zweckstetter; Christian Griesinger; Claudio O Fernández
Site-specific interactions of Cu(II) with alpha and beta-synuclein: bridging the molecular gap between metal binding and aggregation.
Journal of the American Chemical Society 2008;130(35):11801-12.
2008: Nils A Lakomek; Korvin F A Walter; Christophe Farès; oliver lange; Bert L de Groot; Helmut Grubmüller; Rafael Brüschweiler; Axel Munk; Stefan Becker; Jens Meiler; Christian Griesinger
Self-consistent residual dipolar coupling based model-free analysis for the robust determination of nanosecond to microsecond protein dynamics.
Journal of biomolecular NMR 2008;41(3):139-55.
2008: oliver lange; Nils-Alexander Lakomek; Christophe Farès; Gunnar F Schröder; Korvin F A Walter; Stefan Becker; Jens Meiler; Helmut Grubmüller; Christian Griesinger; Bert L de Groot
Recognition dynamics up to microseconds revealed from an RDC-derived ubiquitin ensemble in solution.
Science (New York, N.Y.) 2008;320(5882):1471-5.
2008: Ovidiu C Andronesi; Martin von Bergen; Jacek Biernat; Karsten Seidel; Christian Griesinger; Eckhard Mandelkow; Marc Baldus
Characterization of Alzheimer's-like paired helical filaments from the core domain of tau protein using solid-state NMR spectroscopy.
Journal of the American Chemical Society 2008;130(18):5922-8.
2008: Karsten Seidel; Ovidiu C Andronesi; joachim krebs; Christian Griesinger; Howard S Young; Stefan Becker; Marc Baldus
Structural characterization of Ca(2+)-ATPase-bound phospholamban in lipid bilayers by solid-state nuclear magnetic resonance (NMR) spectroscopy.
Biochemistry 2008;47(15):4369-76.
2008: Marco Lodrini; Tobias Münz; Nicolas Coudevylle; Christian Griesinger; Stefan Becker; Edith Pfitzner
P160/SRC/NCoA coactivators form complexes via specific interaction of their PAS-B domain with the CID/AD1 domain.
Nucleic acids research 2008;36(6):1847-60.
2008: Till von Feilitzsch; Jennifer Tuma; Heike Neubauer; Laurent Verdier; Reinhard Haselsberger; Reiner Feick; Gagik Gurzadyan; Alexander A Voityuk; Christian Griesinger; Maria E Michel-Beyerle
Chromophore/DNA interactions: femto- to nanosecond spectroscopy, NMR structure, and electron transfer theory.
The journal of physical chemistry. B 2008;112(3):973-89.
2008: Julien Orts; Jennifer Tuma; Marcel Reese; S Kaspar Grimm; Peter Monecke; Stefan Bartoschek; Alexander Schiffer; K. Ulrich wendt; Christian Griesinger; Teresa Carlomagno
Crystallography-independent determination of ligand binding modes.
Angewandte Chemie (International ed. in English) 2008;47(40):7736-40.
2008: Julien Orts; S Kaspar Grimm; Christian Griesinger; K. Ulrich wendt; Stefan Bartoschek; Teresa Carlomagno
Specific methyl group protonation for the measurement of pharmacophore-specific interligand NOE interactions.
Chemistry (Weinheim an der Bergstrasse, Germany) 2008;14(25):7517-20.
2008: Valerie S Honndorf; Nicolas Coudevylle; Stefan Laufer; Stefan Becker; Christian Griesinger
Dynamics in the p38alpha MAP kinase-SB203580 complex observed by liquid-state NMR spectroscopy.
Angewandte Chemie (International ed. in English) 2008;47(19):3548-51.
2008: Anne Schuetz; Takanori Murakami; Noboru Takada; Jochen Junker; Masaru Hashimoto; Christian Griesinger
RDC-enhanced NMR spectroscopy in structure elucidation of sucro-neolambertellin.
Angewandte Chemie (International ed. in English) 2008;47(11):2032-4.
2007: Anne Schuetz; Jochen Junker; Andrei Leonov; oliver lange; Tadeusz F Molinski; Christian Griesinger
Stereochemistry of sagittamide A from residual dipolar coupling enhanced NMR.
Journal of the American Chemical Society 2007;129(49):15114-5.
2007: Heike Neubauer; Natalia Gaiko; Sylvia Berger; Jörg Schaffer; Christian Eggeling; Jennifer Tuma; Laurent Verdier; Claus A M Seidel; Christian Griesinger; Andreas Volkmer
Orientational and dynamical heterogeneity of rhodamine 6G terminally attached to a DNA helix revealed by NMR and single-molecule fluorescence spectroscopy.
Journal of the American Chemical Society 2007;129(42):12746-55.
2007: CARLOS WALTER BERTONCINI; Rodolfo Maximiliano Rasia; Gonzalo R Lamberto; Andrés Binolfi; Markus Zweckstetter; Christian Griesinger; Claudio O Fernandez
Structural characterization of the intrinsically unfolded protein beta-synuclein, a natural negative regulator of alpha-synuclein aggregation.
Journal of molecular biology 2007;372(3):708-22.
2007: J Krämer; J D Fischer; Eva Zientz; Vinesh Vijayan; Christian Griesinger; A Lupas; Gottfried Unden
Citrate sensing by the C4-dicarboxylate/citrate sensor kinase DcuS of Escherichia coli: binding site and conversion of DcuS to a C4-dicarboxylate- or citrate-specific sensor.
Journal of bacteriology 2007;189(11):4290-8.
2007: Marco D Mukrasch; Phineus R L Markwick; Jacek Biernat; Martin von Bergen; Pau Bernadó; Christian Griesinger; Eckhard Mandelkow; Markus Zweckstetter; Martin Blackledge
Highly populated turn conformations in natively unfolded tau protein identified from residual dipolar couplings and molecular simulation.
Journal of the American Chemical Society 2007;129(16):5235-43.
2007: Marco D Mukrasch; Martin von Bergen; Jacek Biernat; Daniela Fischer; Christian Griesinger; Eckhard Mandelkow; Markus Zweckstetter
The "jaws" of the tau-microtubule interaction.
The Journal of biological chemistry 2007;282(16):12230-9.
2007: Daniela Fischer; Marco D Mukrasch; Martin von Bergen; Aleksandra Klos-Witkowska; Jacek Biernat; Christian Griesinger; Eckhard Mandelkow; Markus Zweckstetter
Structural and microtubule binding properties of tau mutants of frontotemporal dementias.
Biochemistry 2007;46(10):2574-82.
2007: Marcel Reese; Víctor M Sánchez-Pedregal; Karel Kubicek; Jens Meiler; Marcel J J Blommers; Christian Griesinger; Teresa Carlomagno
Structural basis of the activity of the microtubule-stabilizing agent epothilone a studied by NMR spectroscopy in solution.
Angewandte Chemie (International ed. in English) 2007;46(11):1864-8.
2006: Andrés Binolfi; Rodolfo Maximiliano Rasia; CARLOS WALTER BERTONCINI; Marcelo Ceolin; Markus Zweckstetter; Christian Griesinger; Thomas M Jovin; Claudio O Fernández
Interaction of alpha-synuclein with divalent metal ions reveals key differences: a link between structure, binding specificity and fibrillation enhancement.
Journal of the American Chemical Society 2006;128(30):9893-901.
2006: Fernando Rodriguez-Castañeda; Peter Haberz; Andrei Leonov; Christian Griesinger
Paramagnetic tagging of diamagnetic proteins for solution NMR.
Magnetic resonance in chemistry : MRC 2006;44 Spec No():S10-6.
2006: Sebastian Dziadek; Christian Griesinger; Horst Kunz; Uwe M Reinscheid
Synthesis and structural model of an alpha(2,6)-sialyl-t glycosylated MUC1 eicosapeptide under physiological conditions.
Chemistry (Weinheim an der Bergstrasse, Germany) 2006;12(19):4981-93.
2006: Jonathan Farjon; Wolfgang Bermel; Christian Griesinger
Resolution enhancement in spectra of natural products dissolved in weakly orienting media with the help of 1H homonuclear dipolar decoupling during acquisition: application to 1H-13C dipolar couplings measurements.
Journal of magnetic resonance (San Diego, Calif. : 1997) 2006;180(1):72-82.
2006: Anthony G M Barrett; Rachel A James; Gillian E Morton; Panayiotis A Procopiou; Christian Boehme; Armin de Meijere; Christian Griesinger; Uwe M Reinscheid
Helical structure of tercyclopropanedimethanol in solution.
The Journal of organic chemistry 2006;71(7):2756-9.
2006: Peter Haberz; Fernando Rodriguez-Castañeda; Jochen Junker; Stefan Becker; Andrei Leonov; Christian Griesinger
Two new chiral EDTA-based metal chelates for weak alignment of proteins in solution.
Organic letters 2006;8(7):1275-8.
2006: Nils A Lakomek; Teresa Carlomagno; Stefan Becker; Christian Griesinger; Jens Meiler
A thorough dynamic interpretation of residual dipolar couplings in ubiquitin.
Journal of biomolecular NMR 2006;34(2):101-15.
2006: Uwe M Reinscheid; Jonathan Farjon; Markus Radzom; Peter Haberz; Axel Zeeck; Martin Blackledge; Christian Griesinger
Effect of the solvent on the conformation of a depsipeptide: NMR-derived solution structure of hormaomycin in DMSO from residual dipolar couplings in a novel DMSO-compatible alignment medium.
Chembiochem : a European journal of chemical biology 2006;7(2):287-96.
2005: Pau Bernadó; CARLOS WALTER BERTONCINI; Christian Griesinger; Markus Zweckstetter; Martin Blackledge
Defining long-range order and local disorder in native alpha-synuclein using residual dipolar couplings.
Journal of the American Chemical Society 2005;127(51):17968-9.
2005: Nils A Lakomek; Christophe Farès; Stefan Becker; Teresa Carlomagno; Jens Meiler; Christian Griesinger
Side-chain orientation and hydrogen-bonding imprint supra-Tau(c) motion on the protein backbone of ubiquitin.
Angewandte Chemie (International ed. in English) 2005;44(47):7776-8.
2005: CARLOS WALTER BERTONCINI; Claudio O Fernandez; Christian Griesinger; Thomas M Jovin; Markus Zweckstetter
Familial mutants of alpha-synuclein with increased neurotoxicity have a destabilized conformation.
The Journal of biological chemistry 2005;280(35):30649-52.
2005: Víctor M Sánchez-Pedregal; Marcel Reese; Jens Meiler; Marcel J J Blommers; Christian Griesinger; Teresa Carlomagno
The INPHARMA method: protein-mediated interligand NOEs for pharmacophore mapping.
Angewandte Chemie (International ed. in English) 2005;44(27):4172-5.
2005: Marco D Mukrasch; Jacek Biernat; Martin von Bergen; Christian Griesinger; Eckhard Mandelkow; Markus Zweckstetter
Sites of tau important for aggregation populate {beta}-structure and bind to microtubules and polyanions.
The Journal of biological chemistry 2005;280(26):24978-86.
2005: Holger Kneuper; Ingo G Janausch; Vinesh Vijayan; Markus Zweckstetter; Verena Bock; Christian Griesinger; Gottfried Unden
The nature of the stimulus and of the fumarate binding site of the fumarate sensor DcuS of Escherichia coli.
The Journal of biological chemistry 2005;280(21):20596-603.
2005: Andrei Leonov; Brigitte Voigt; Fernando Rodriguez-Castañeda; Peyman Sakhaii; Christian Griesinger
Convenient synthesis of multifunctional EDTA-based chiral metal chelates substituted with an S-mesylcysteine.
Chemistry (Weinheim an der Bergstrasse, Germany) 2005;11(11):3342-8.
2005: Uwe M Reinscheid; Boris D Zlatopolskiy; Christian Griesinger; Axel Zeeck; Armin de Meijere
The structure of hormaomycin and one of its all-peptide aza-analogues in solution: syntheses and biological activities of new hormaomycin analogues.
Chemistry (Weinheim an der Bergstrasse, Germany) 2005;11(10):2929-45.
2005: Karsten Seidel; Manuel Etzkorn; Lars Sonnenberg; Christian Griesinger; Angelika Sebald; Marc Baldus
Studying molecular 3D structure and dynamics by high-resolution solid-state NMR: Application to L-tyrosine-ethylester.
The journal of physical chemistry. A 2005;109(11):2436-42.
2005: Rodolfo Maximiliano Rasia; CARLOS WALTER BERTONCINI; Derek Marsh; Wolfgang Hoyer; Dmitry Cherny; Markus Zweckstetter; Christian Griesinger; Thomas M Jovin; Claudio O Fernández
Structural characterization of copper(II) binding to alpha-synuclein: Insights into the bioinorganic chemistry of Parkinson's disease.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(12):4294-9.
2005: Xiulan Xie; Lo'ay Al-Momani; Philipp Reiss; Christian Griesinger; Ulrich Koert
An asymmetric ion channel derived from gramicidin A. Synthesis, function and NMR structure.
The FEBS journal 2005;272(4):975-86.
2005: CARLOS WALTER BERTONCINI; Young-Sang Jung; Claudio O Fernandez; Wolfgang Hoyer; Christian Griesinger; Thomas M Jovin; Markus Zweckstetter
Release of long-range tertiary interactions potentiates aggregation of natively unstructured alpha-synuclein.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(5):1430-5.
2005: Ana M Neculai; Dante Neculai; Christian Griesinger; Julia A Vorholt; Stefan Becker
A dynamic zinc redox switch.
The Journal of biological chemistry 2005;280(4):2826-30.
2005: Peter Haberz; Jonathan Farjon; Christian Griesinger
A DMSO-compatible orienting medium: towards the investigation of the stereochemistry of natural products.
Angewandte Chemie (International ed. in English) 2005;44(3):427-9.
2004: Takahisa Ikegami; Laurent Verdier; Peyman Sakhaii; Susanne Grimme; Barbara Pescatore; Krishna Saxena; Klaus M Fiebig; Christian Griesinger
Novel techniques for weak alignment of proteins in solution using chemical tags coordinating lanthanide ions.
Journal of biomolecular NMR 2004;29(3):339-49.
2004: Burkhard Luy; Alexander Diener; Rolf-Peter Hummel; Ernst Sturm; Wolf-Rüdiger Ulrich; Christian Griesinger
Structure and potential C-terminal dimerization of a recombinant mutant of surfactant-associated protein C in chloroform/methanol.
European journal of biochemistry / FEBS 2004;271(11):2076-85.
2004: Claudio O Fernández; Wolfgang Hoyer; Markus Zweckstetter; Elizabeth Jares-Erijman; Vinod Subramaniam; Christian Griesinger; Thomas M Jovin
NMR of alpha-synuclein-polyamine complexes elucidates the mechanism and kinetics of induced aggregation.
The EMBO journal 2004;23(10):2039-46.
2004: Seigo Shima; Erica J Lyon; Melanie Sordel-Klippert; Manuela Kauss; Jörg Kahnt; Rudolf K Thauer; Klaus Steinbach; Xiulan Xie; Laurent Verdier; Christian Griesinger
The cofactor of the iron-sulfur cluster free hydrogenase hmd: structure of the light-inactivation product.
Angewandte Chemie (International ed. in English) 2004;43(19):2547-51.
2004: Adelia Razeto; Venkatesh Ramakrishnan; Claudia M Litterst; Karin Giller; Christian Griesinger; Teresa Carlomagno; Nils A Lakomek; Thomas Heimburg; Marco Lodrini; Edith Pfitzner; Stefan Becker
Structure of the NCoA-1/SRC-1 PAS-B domain bound to the LXXLL motif of the STAT6 transactivation domain.
Journal of molecular biology 2004;336(2):319-29.
2004: Christian Griesinger; Wolfgang Peti; Jens Meiler; Rafael Brüschweiler
Projection angle restraints for studying structure and dynamics of biomolecules.
Methods in molecular biology (Clifton, N.J.) 2004;278():107-21.
2003: Stefan Bartoschek; Gerrit Buurman; Bernhard H Geierstanger; Jon Lapham; Christian Griesinger
Measurement and ab initio calculation of CSA/dipole-dipole cross-correlated relaxation provide insight into the mechanism of a H2-forming dehydrogenase.
Journal of the American Chemical Society 2003;125(44):13308-9.
2003: Lucia Pappalardo; Ingo G Janausch; Vinesh Vijayan; Eva Zientz; Jochen Junker; Wolfgang Peti; Markus Zweckstetter; Gottfried Unden; Christian Griesinger
The NMR structure of the sensory domain of the membranous two-component fumarate sensor (histidine protein kinase) DcuS of Escherichia coli.
The Journal of biological chemistry 2003;278(40):39185-8.
2003: Teresa Carlomagno; Wolfgang Bermel; Christian Griesinger
Measuring the chi 1 torsion angle in protein by CH-CH cross-correlated relaxation: a new resolution-optimised experiment.
Journal of biomolecular NMR 2003;27(2):151-7.
2003: Michael Karle; Dirk Bockelmann; Dirk Schumann; Christian Griesinger; Ulrich Koert
Conformative coupling of two conformational molecular switches.
Angewandte Chemie (International ed. in English) 2003;42(37):4546-9.
2003: Marc Kipping; Hauke Lilie; Ute Lindenstrauss; Jan R Andreesen; Christian Griesinger; Teresa Carlomagno; Thomas Brüser
Structural studies on a twin-arginine signal sequence.
FEBS letters 2003;550(1-3):18-22.
2003: Martin Vogtherr; Susanne Grimme; Bettina Elshorst; Doris M Jacobs; Klaus M Fiebig; Christian Griesinger; Ralph Zahn
Antimalarial drug quinacrine binds to C-terminal helix of cellular prion protein.
Journal of medicinal chemistry 2003;46(17):3563-4.
2003: Laurent Verdier; Peyman Sakhaii; Markus Zweckstetter; Christian Griesinger
Measurement of long range H,C couplings in natural products in orienting media: a tool for structure elucidation of natural products.
Journal of magnetic resonance (San Diego, Calif. : 1997) 2003;163(2):353-9.
2003: Teresa Carlomagno; Víctor M Sánchez; Marcel J J Blommers; Christian Griesinger
Derivation of dihedral angles from CH-CH dipolar-dipolar cross-correlated relaxation rates: a C-C torsion involving a quaternary carbon atom in epothilone A bound to tubulin.
Angewandte Chemie (International ed. in English) 2003;42(22):2515-7.
2003: Teresa Carlomagno; Marcel J J Blommers; Jens Meiler; Wolfgang Jahnke; Thomas Schupp; Frank Petersen; Dieter Schinzer; Karl-Heinz Altmann; Christian Griesinger
The high-resolution solution structure of epothilone A bound to tubulin: an understanding of the structure-activity relationships for a powerful class of antitumor agents.
Angewandte Chemie (International ed. in English) 2003;42(22):2511-5.
2002: Michael C Hutter; joachim krebs; Jens Meiler; Christian Griesinger; Ernesto Carafoli; Volkhard Helms
A structural model of the complex formed by phospholamban and the calcium pump of sarcoplasmic reticulum obtained by molecular mechanics.
Chembiochem : a European journal of chemical biology 2002;3(12):1200-8.
2002: Wolfgang Peti; Jens Meiler; Rafael Brüschweiler; Christian Griesinger
Model-free analysis of protein backbone motion from residual dipolar couplings.
Journal of the American Chemical Society 2002;124(20):5822-33.
2002: Martin Vogtherr; Doris M Jacobs; Tatjana N Parac; Marcus Maurer; Andreas Pahl; Krishna Saxena; Heinz Rüterjans; Christian Griesinger; Klaus M Fiebig
NMR solution structure and dynamics of the peptidyl-prolyl cis-trans isomerase domain of the trigger factor from Mycoplasma genitalium compared to FK506-binding protein.
Journal of molecular biology 2002;318(4):1097-115.
2002: Meike Goenrich; Stefan Bartoschek; Christoph H Hagemeier; Christian Griesinger; Julia A Vorholt
A glutathione-dependent formaldehyde-activating enzyme (Gfa) from Paracoccus denitrificans detected and purified via two-dimensional proton exchange NMR spectroscopy.
The Journal of biological chemistry 2002;277(5):3069-72.
2002: Christian Hoffmann; Dierk Blechschmidt; Ralf Krüger; Michael Karas; Christian Griesinger
Mass spectrometric sequencing of individual peptides from combinatorial libraries via specific generation of chain-terminated sequences.
Journal of combinatorial chemistry 2002;4(1):79-86.
2001: Stefan Bartoschek; M Johansson; Bernhard H Geierstanger; J G Okun; Roy Lancaster; E Humpfer; L Yu; C A Yu; Christian Griesinger; Ulrich Brandt
Three molecules of ubiquinone bind specifically to mitochondrial cytochrome bc1 complex.
The Journal of biological chemistry 2001;276(38):35231-4.
2001: Stefan Bartoschek; Gerrit Buurman; Rudolf K Thauer; Bernhard H Geierstanger; J P Weyrauch; Christian Griesinger; Michael Nilges; Michael C Hutter; Volkhard Helms
Re-face stereospecificity of methylenetetrahydromethanopterin and methylenetetrahydrofolate dehydrogenases is predetermined by intrinsic properties of the substrate.
Chembiochem : a European journal of chemical biology 2001;2(7-8):530-41.
2001: Teresa Carlomagno; Marcel J J Blommers; Jens Meiler; Bernard Cuenoud; Christian Griesinger
Determination of aliphatic side-chain conformation using cross-correlated relaxation: application to an extraordinarily stable 2'-aminoethoxy-modified oligonucleotide triplex.
Journal of the American Chemical Society 2001;123(30):7364-70.
2001: Jens Meiler; Jeanine J Prompers; Wolfgang Peti; Christian Griesinger; Rafael Brüschweiler
Model-free approach to the dynamic interpretation of residual dipolar couplings in globular proteins.
Journal of the American Chemical Society 2001;123(25):6098-107.
2001: M Baumann; H Bischoff; D Schmidt; Christian Griesinger
Combinatorial synthesis of cholesterol ester transfer protein-mRNA ligands and screening by nondenaturating gel-electrophoresis.
Journal of medicinal chemistry 2001;44(13):2172-7.
2001: Tatjana N Parac; Martin Vogtherr; M Maurer; A Pahl; H Rüterjansl; Christian Griesinger; Klaus M Fiebig
Assignment of the 1H, 13C and 15N resonances of the PPIase domain of the trigger factor from Mycoplasma genitalium.
Journal of biomolecular NMR 2001;20(2):193-4.
2001: Christoph H Hagemeier; Stefan Bartoschek; Christian Griesinger; Rudolf K Thauer; Julia A Vorholt
Re-face stereospecificity of NADP dependent methylenetetrahydromethanopterin dehydrogenase from Methylobacterium extorquens AM1 as determined by NMR spectroscopy.
FEBS letters 2001;494(1-2):95-8.
2001: Tatjana N Parac; B Coligaev; Eva Zientz; Gottfried Unden; W Pet; Christian Griesinger
Assignment of 1H, 13C and 15N resonances to the sensory domain of the membraneous two-component fumarate sensor (histidine protein kinase) DcuS of Escherichia coli.
Journal of biomolecular NMR 2001;19(1):91-2.
2000: Wolfgang Peti; Christian Griesinger; Wolfgang Bermel
Adiabatic TOCSY for C,C and H,H J-transfer.
Journal of biomolecular NMR 2000;18(3):199-205.
2000: Jens Meiler; Wolfgang Peti; Christian Griesinger
DipoCoup: A versatile program for 3D-structure homology comparison based on residual dipolar couplings and pseudocontact shifts.
Journal of biomolecular NMR 2000;17(4):283-94.
2000: Teresa Carlomagno; Wolfgang Peti; Christian Griesinger
A new method for the simultaneous measurement of magnitude and sign of 1DCH and 1DHH dipolar couplings in methylene groups.
Journal of biomolecular NMR 2000;17(2):99-109.
2000: Teresa Carlomagno; Christian Griesinger
Errors in the measurement of cross-correlated relaxation rates and how to avoid them.
Journal of magnetic resonance (San Diego, Calif. : 1997) 2000;144(2):280-7.
2000: Stefan Bartoschek; Julia A Vorholt; Rudolf K Thauer; Bernhard H Geierstanger; Christian Griesinger
N-carboxymethanofuran (carbamate) formation from methanofuran and CO2 in methanogenic archaea. Thermodynamics and kinetics of the spontaneous reaction.
European journal of biochemistry / FEBS 2000;267(11):3130-8.
2000: Jens Meiler; N Blomberg; Michael Nilges; Christian Griesinger
A new approach for applying residual dipolar couplings as restraints in structure elucidation.
Journal of biomolecular NMR 2000;16(3):245-52.
2000: Bernd Reif; Alexander Diener; Mirko Hennig; M Maurer; Christian Griesinger
Cross-correlated relaxation for the measurement of angles between tensorial interactions.
Journal of magnetic resonance (San Diego, Calif. : 1997) 2000;143(1):45-68.
1999: Christian Richter; Christian Griesinger; I Felli; P T Cole; G Varani; Harald Schwalbe
Determination of sugar conformation in large RNA oligonucleotides from analysis of dipole-dipole cross correlated relaxation by solution NMR spectroscopy.
Journal of biomolecular NMR 1999;15(3):241-50.
1999: Bettina Elshorst; Mirko Hennig; H Försterling; Alexander Diener; M Maurer; P Schulte; Harald Schwalbe; Christian Griesinger; joachim krebs; H Schmid; T Vorherr; Ernesto Carafoli
NMR solution structure of a complex of calmodulin with a binding peptide of the Ca2+ pump.
Biochemistry 1999;38(38):12320-32.
1998: Teresa Carlomagno; Harald Schwalbe; A Rexroth; O W Sorensen; Christian Griesinger
New methylene specific experiments for the measurement of scalar spin-spin coupling constants between protons attached to 13C.
Journal of magnetic resonance (San Diego, Calif. : 1997) 1998;135(1):216-26.
1998: Christian Richter; Bernd Reif; K Wörner; S Quant; John P Marino; J W Engels; Christian Griesinger; Harald Schwalbe
A New Experiment for the Measurement of nJ(C,P) Coupling Constants Including 3J(C4'i,Pi) and 3J(C4'i,Pi+1) in Oligonucleotides.
Journal of biomolecular NMR 1998;12(2):223-30.
1997: H Weinberger; E Lichte; Christian Griesinger; B Kutscher
Small peptide libraries: combinatorial split-mix synthesis followed by combinatorial amino acid analysis of selected variants.
Archiv der Pharmazie 1997;330(4):109-11.
1997: T Prasch; T Naumann; R L Markert; M Sattler; W Schubert; S Schaal; M Bauch; Herbert Kogler; Christian Griesinger
Constitution and solution conformation of the antibiotic mersacidin determined by NMR and molecular dynamics.
European journal of biochemistry / FEBS 1997;244(2):501-12.
1996: Teresa Carlomagno; Steffen J Glaser; M Maurer; M Sattler; M G Schwendinger; Christian Griesinger
PLUSH TACSY: Homonuclear planar TACSY with two-band selective shaped pulses applied to C(α),C' transfer and C (β),C (aromatic) correlations.
Journal of biomolecular NMR 1996;8(2):161-70.
1996: S J Glaser; Harald Schwalbe; John P Marino; Christian Griesinger
Directed TOCSY, a method for selection of directed correlations by optimal combinations of isotropic and longitudinal mixing.
Journal of magnetic resonance. Series B 1996;112(2):160-80.
1996: R L Markert; H Ruppach; S Gehring; Ursula Dietrich; D F Mierke; M Köck; Helga Rübsamen-Waigmann; Christian Griesinger
Secondary structural elements as a basis for antibody recognition in the immunodominant region of human immunodeficiency viruses 1 and 2.
European journal of biochemistry / FEBS 1996;237(1):188-204.
1995: A Rexroth; Harald Schwalbe; S Szalma; R Weisemann; Wolfgang Bermel; Christian Griesinger
Determination of (3)J(H (infi) (supN) ,C (infi) (sup') ) coupling constants in proteins with the C'-FIDS method.
Journal of biomolecular NMR 1995;6(3):237-44.
1995: M Sattler; J Schleucher; M G Schwendinger; Christian Griesinger
Novel strategies for sensitivity enhancement in heteronuclear multi-dimensional NMR experiments employing pulsed field gradients.
Journal of biomolecular NMR 1995;6(1):11-22.
1995: M Sattler; J Schleucher; M Maurer; Christian Griesinger
A simultaneous (15)N, (1)H- and (13)C, (1)H-HSQC with sensitivity enhancement and a heteronuclear gradient echo.
Journal of biomolecular NMR 1995;5(1):97-102.
1995: John P Marino; Harald Schwalbe; Clemens Anklin; W Bermel; Donald M Crothers; Christian Griesinger
Sequential correlation of anomeric ribose protons and intervening phosphorus in RNA oligonucleotides by a 1H, 13C, 31P triple resonance experiment: HCP-CCH-TOCSY.
Journal of biomolecular NMR 1995;5(1):87-92.
1994: Harald Schwalbe; John P Marino; G C King; Rainer Wechselberger; W Bermel; Christian Griesinger
Determination of a complete set of coupling constants in 13C-labeled oligonucleotides.
Journal of biomolecular NMR 1994;4(5):631-44.
1994: J Schleucher; Christian Griesinger; B Schwörer; Rudolf K Thauer
H2-forming N5, N10-methylenetetrahydromethanopterin dehydrogenase from Methanobacterium thermoautotrophicum catalyzes a stereoselective hydride transfer as determined by two-dimensional NMR spectroscopy.
Biochemistry 1994;33(13):3986-93.
1994: R Weisemann; Wolfgang Bermel; Heinz Rüterjans; J Schleucher; Harald Schwalbe; Christian Griesinger
Determination of H(N),H (α) and H (N),C' coupling constants in (13)C, (15)N-labeled proteins.
Journal of biomolecular NMR 1994;4(2):231-40.
1994: J Schleucher; M Schwendinger; M Sattler; P Schmidt; O Schedletzky; S J Glaser; O W Sørensen; Christian Griesinger
A general enhancement scheme in heteronuclear multidimensional NMR employing pulsed field gradients.
Journal of biomolecular NMR 1994;4(2):301-6.
1993: M J Blackledge; R Brüschweiler; Christian Griesinger; J M Schmidt; P Xu; RR Ernst
Conformational backbone dynamics of the cyclic decapeptide antamanide. Application of a new multiconformational search algorithm based on NMR data.
Biochemistry 1993;32(41):10960-74.
1992: J Schleucher; B Schwörer; C Zirngibl; U Koch; W Weber; E Egert; Rudolf K Thauer; Christian Griesinger
Determination of the relative configuration of 5,6,7,8-tetrahydromethanopterin by two-dimensional NMR spectroscopy.
FEBS letters 1992;314(3):440-4.
1988: Hartmut Oschkinat; Christian Griesinger; P J Kraulis; O W Sørensen; RR Ernst; A M Gronenborn; G M Clore
Three-dimensional NMR spectroscopy of a protein in solution.
Nature 1988;332(6162):374-6.