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Brunilde Gril

Research Profile

Chemicals & Drugs

Disorders

Anatomy

Tumor Cell Line

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Xenograft Model Antitumor Assays

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Publications

TOP 3
Kunal S Taskar; Helen R Thorsheim; Patricia S Steeg; Stephen Castellino; Brunilde Gril; Emily Hua; Julie Lockman; Paul R Lockman; Rajendar K Mittapalli; Diane Palmieri; Joseph W Polli; Stephen D Rubin; Vinay Rudraraju; Ramakrishna Samala; Quentin R Smith
Lapatinib distribution in HER2 overexpressing experimental brain metastases of breast cancer.
Brunilde Gril; Lilia Ileva; David J Liewehr; Diane Palmieri; Yong Qian; Talha Anwar; Marcelino Bernardo; Peter Choyke; Seth M Steinberg; Patricia S Steeg
The B-Raf status of tumor cells may be a significant determinant of both antitumor and anti-angiogenic effects of pazopanib in xenograft tumor models.
Brunilde Gril; Diane Palmieri; Yong Qian; DeeDee Smart; Lilia Ileva; David J Liewehr; Seth M Steinberg; Patricia S Steeg
Pazopanib reveals a role for tumor cell B-Raf in the prevention of HER2+ breast cancer brain metastasis.

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All Publications

2012: Kunal S Taskar; Helen R Thorsheim; Patricia S Steeg; Stephen Castellino; Brunilde Gril; Emily Hua; Julie Lockman; Paul R Lockman; Rajendar K Mittapalli; Diane Palmieri; Joseph W Polli; Stephen D Rubin; Vinay Rudraraju; Ramakrishna Samala; Quentin R Smith
Lapatinib distribution in HER2 overexpressing experimental brain metastases of breast cancer.
Pharmaceutical research 2012;29(3):770-81.
2011: Brunilde Gril; Lilia Ileva; David J Liewehr; Diane Palmieri; Yong Qian; Talha Anwar; Marcelino Bernardo; Peter Choyke; Seth M Steinberg; Patricia S Steeg
The B-Raf status of tumor cells may be a significant determinant of both antitumor and anti-angiogenic effects of pazopanib in xenograft tumor models.
PloS one 2011;6(10):e25625.
2011: Brunilde Gril; Diane Palmieri; Yong Qian; DeeDee Smart; Lilia Ileva; David J Liewehr; Seth M Steinberg; Patricia S Steeg
Pazopanib reveals a role for tumor cell B-Raf in the prevention of HER2+ breast cancer brain metastasis.
Clinical cancer research : an official journal of the American Association for Cancer Research 2011;17(1):142-53.
2010: Paul R Lockman; Rajendar K Mittapalli; Kunal S Taskar; Vinay Rudraraju; Brunilde Gril; Kaci A Bohn; Chris E Adkins; Amanda Roberts; Helen R Thorsheim; Julie A Gaasch; Suyun Huang; Diane Palmieri; Patricia S Steeg; Quentin R Smith
Heterogeneous blood-tumor barrier permeability determines drug efficacy in experimental brain metastases of breast cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2010;16(23):5664-78.
2010: Charles L Vogel; Arlene Chan; Brunilde Gril; Sung-Bae Kim; Junichi Kurebayashi; Li Liu; Yen-Shen Lu; Hanlim Moon
Management of ErbB2-positive breast cancer: insights from preclinical and clinical studies with lapatinib.
Japanese journal of clinical oncology 2010;40(11):999-1013.
2010: Brunilde Gril; Lynda Evans; Diane Palmieri; Patricia S Steeg
Translational research in brain metastasis is identifying molecular pathways that may lead to the development of new therapeutic strategies.
European journal of cancer (Oxford, England : 1990) 2010;46(7):1204-10.
2008: perayot Pamonsinlapatham; Brunilde Gril; Sylvie Dufour; Réda Hadj-Slimane; Véronique Gigoux; Stéphanie Pethe; Sébastien L'Hoste; Jacques Camonis; Christiane Garbay; Françoise Raynaud; Michel Vidal
Capns1, a new binding partner of RasGAP-SH3 domain in K-Ras(V12) oncogenic cells: modulation of cell survival and migration.
Cellular signalling 2008;20(11):2119-26.
2008: Brunilde Gril; Diane Palmieri; Julie L Bronder; Jeanne M Herring; Eleazar Vega-Valle; Lionel Feigenbaum; David J Liewehr; Seth M Steinberg; Maria J Merino; Stephen D Rubin; Patricia S Steeg
Effect of lapatinib on the outgrowth of metastatic breast cancer cells to the brain.
Journal of the National Cancer Institute 2008;100(15):1092-103.
2008: Jean-Philippe Luzy; Huixiong Chen; Brunilde Gril; Wang-Qing Liu; Michel Vidal; Dominique Perdereau; Anne-Françoise Burnol; Christiane Garbay
Development of binding assays for the SH2 domain of Grb7 and Grb2 using fluorescence polarization.
Journal of biomolecular screening 2008;13(2):112-9.
2007: Brunilde Gril; Michel Vidal; Franck Assayag; Marie-France Poupon; Wang-Qing Liu; Christiane Garbay
Grb2-SH3 ligand inhibits the growth of HER2+ cancer cells and has antitumor effects in human cancer xenografts alone and in combination with docetaxel.
International journal of cancer. Journal international du cancer 2007;121(2):407-15.
2006: Brunilde Gril; Wang-Qing Liu; Christine Lenoir; Christiane Garbay; Michel Vidal
Affinity chromatography for purification of the modular protein growth factor receptor-bound protein 2 and development of a screening test for growth factor receptor-bound protein 2 Src homology 3 domain inhibitor using peroxidase-linked ligand.
Analytical biochemistry 2006;351(1):93-9.
2006: Diane Palmieri; Quentin R Smith; Paul R Lockman; Julie L Bronder; Brunilde Gril; Ann F Chambers; Robert J Weil; Patricia S Steeg
Brain metastases of breast cancer.
Breast disease 2006;26():139-47.
2004: Michel Vidal; Wang-Qing Liu; Brunilde Gril; Franck Assayag; Marie-France Poupon; Christiane Garbay
[Design of new anti-tumor agents interrupting deregulated signaling pathways induced by tyrosine kinase proteins. Inhibition of protein-protein interaction involving Grb2].
Journal de la Société de biologie 2004;198(2):133-7.