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Luigi Grimaldi

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Italy

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Francesco Patti; Orietta Picconi; Maria Rosalia Tola; Maria Trojano; Maria Pia Amato; Stefano Bastianello; Cilia Sabina; Salvatore Cottone; Luigi M E Grimaldi
Longitudinal changes in social functioning in mildly disabled patients with relapsing-remitting multiple sclerosis receiving subcutaneous interferon β-1a: results from the COGIMUS (COGnitive Impairment in MUltiple Sclerosis) study (II).
Antonella Marino Gammazza; Arcangelo Benigno; Fabio Bucchieri; Luigi M E Grimaldi; Alberto J L Macario; Giovanni Zummo; Everly Conway de Macario; Francesco Cappello
The molecular anatomy of human Hsp60 and its similarity with that of bacterial orthologs and acetylcholine receptor reveal a potential pathogenetic role of anti-chaperonin immunity in myasthenia gravis.
Michele Mishto; Elena Bellavista; Claudia Ligorio; Kathrin Textoris-Taube; Aurelia Santoro; Mara Giordano; Sandra D'Alfonso; Florinda Listì; Benedetta Nacmias; Elena Cellini; Maurizio Leone; Luigi M E Grimaldi; Chiara Fenoglio; Federica Esposito; Filippo Martinelli Boneschi; Daniela Galimberti; Elio Scarpini; Ulrike Seifert; Maria Pia Amato; Calogero Caruso; Maria P Foschini; Peter M Kloetzel; Claudio Franceschi
Immunoproteasome LMP2 60HH variant alters MBP epitope generation and reduces the risk to develop multiple sclerosis in Italian female population.

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All Publications

2012: Francesco Patti; Orietta Picconi; Maria Rosalia Tola; Maria Trojano; Maria Pia Amato; Stefano Bastianello; Cilia Sabina; Salvatore Cottone; Luigi M E Grimaldi
Longitudinal changes in social functioning in mildly disabled patients with relapsing-remitting multiple sclerosis receiving subcutaneous interferon β-1a: results from the COGIMUS (COGnitive Impairment in MUltiple Sclerosis) study (II).
Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation 2012;21(7):1111-21.
2012: Antonella Marino Gammazza; Arcangelo Benigno; Fabio Bucchieri; Luigi M E Grimaldi; Alberto J L Macario; Giovanni Zummo; Everly Conway de Macario; Francesco Cappello
The molecular anatomy of human Hsp60 and its similarity with that of bacterial orthologs and acetylcholine receptor reveal a potential pathogenetic role of anti-chaperonin immunity in myasthenia gravis.
Cellular and molecular neurobiology 2012;32(6):943-7.
2010: Michele Mishto; Elena Bellavista; Claudia Ligorio; Kathrin Textoris-Taube; Aurelia Santoro; Mara Giordano; Sandra D'Alfonso; Florinda Listì; Benedetta Nacmias; Elena Cellini; Maurizio Leone; Luigi M E Grimaldi; Chiara Fenoglio; Federica Esposito; Filippo Martinelli Boneschi; Daniela Galimberti; Elio Scarpini; Ulrike Seifert; Maria Pia Amato; Calogero Caruso; Maria P Foschini; Peter M Kloetzel; Claudio Franceschi
Immunoproteasome LMP2 60HH variant alters MBP epitope generation and reduces the risk to develop multiple sclerosis in Italian female population.
PloS one 2010;5(2):e9287.
2009: G Tedeschi; M P Amato; R D'Alessandro; F Drago; C Milanese; Patrizia Popoli; P Rossi; Giovanni Savettieri; Maria Rosaria Tola; Nicola Vanacore; Anna Covezzoli; M De Rosa; G Comi; Carlo Pozzilli; Antonio Bertolotto; Maria Giovanna Marrosu; Luigi M E Grimaldi; Carlo Piccinni; N Montanaro; Laura Periotto; Rosamaria Iommelli; Antonio Addis; Nello Martini; Leandro Provinciali; G L Mancardi
The pharmacovigilance program on natalizumab in Italy: 2 years of experience.
Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 2009;30 Suppl 2():S163-5.
2007: Luigi M E Grimaldi; Barbara Palmeri; Giuseppe Salemi; Giuseppe Giglia; Marco D'Amelio; Roberto Grimaldi; Gaetano Vitello; Paolo Ragonese; Giovanni Savettieri
High prevalence and fast rising incidence of multiple sclerosis in Caltanissetta, Sicily, southern Italy.
Neuroepidemiology 2007;28(1):28-32.
2005: Federico Licastro; Martina Chiappelli; Luigi M E Grimaldi; Kevin Morgan; Noor Kalsheker; Elena Calabrese; Alistair Ritchie; Elisa Porcellini; Giuliana Salani; Massimo Franceschi; Nicola Canal
A new promoter polymorphism in the alpha-1-antichymotrypsin gene is a disease modifier of Alzheimer's disease.
Neurobiology of aging 2005;26(4):449-53.
2005: Giulia Malferrari; A Stella; Eugenia Monferini; Giuliana Saltini; Maria Carla Proverbio; Luigi M E Grimaldi; Luigi Rossi Bernardi; Ida Biunno
Ctla4 and multiple sclerosis in the Italian population.
Experimental and molecular pathology 2005;78(1):55-7.
2005: Andreas Papassotiropoulos; jean-charles lambert; Fabienne Wavrant-De Vrièze; M Axel Wollmer; Heinz von der Kammer; Johannes R Streffer; Alessia Maddalena; Kim-Dung Huynh; Sibylle Wolleb; Dieter Lutjohann; Brigitte Schneider; Dietmar R Thal; Luigi M E Grimaldi; Magdalini Tsolaki; Elisabeth Kapaki; Rivka Ravid; Uwe Konietzko; Thomas Hegi; Thomas Pasch; Hans Jung; Heiko Braak; Philippe Amouyel; Evgeny I Rogaev; John Hardy; Christoph Hock; Roger M Nitsch
Cholesterol 25-hydroxylase on chromosome 10q is a susceptibility gene for sporadic Alzheimer's disease.
Neuro-degenerative diseases 2005;2(5):233-41.
2004: Federico Licastro; Fabrizio Veglia; Martina Chiappelli; Luigi M E Grimaldi; Eliezer Masliah
A polymorphism of the interleukin-1 beta gene at position +3953 influences progression and neuro-pathological hallmarks of Alzheimer's disease.
Neurobiology of aging 2004;25(8):1017-22.
2004: Innocenzo Rainero; Luigi M E Grimaldi; Giuliana Salani; Walter Valfrè; Chiara Rivoiro; Lidia Savi; Lorenzo Pinessi
Association between the tumor necrosis factor-alpha -308 G/A gene polymorphism and migraine.
Neurology 2004;62(1):141-3.
2004: Dominique J-F de Quervain; Raphael Poirier; M Axel Wollmer; Luigi M E Grimaldi; Magdalini Tsolaki; Johannes R Streffer; Christoph Hock; Roger M Nitsch; M Hasan Mohajeri; Andreas Papassotiropoulos
Glucocorticoid-related genetic susceptibility for Alzheimer's disease.
Human molecular genetics 2004;13(1):47-52.
2003: Francesca L Sciacca; C Ferri; Federico Licastro; Fabrizio Veglia; Ida Biunno; A Gavazzi; Elena Calabrese; Filippo Martinelli Boneschi; Sandro Sorbi; Claudio Mariani; Massimo Franceschi; Luigi M E Grimaldi
Interleukin-1B polymorphism is associated with age at onset of Alzheimer's disease.
Neurobiology of aging 2003;24(7):927-31.
2003: Federico Licastro; Luigi M E Grimaldi; Massimiliano Bonafè; Chiappelli Martina; Fabiola Olivieri; Luca Cavallone; Simona Giovanietti; Eliezer Masliah; Claudio Franceschi
Interleukin-6 gene alleles affect the risk of Alzheimer's disease and levels of the cytokine in blood and brain.
Neurobiology of aging 2003;24(7):921-6.
2003: Luigi M E Grimaldi; A Pincherle; Filippo Martinelli Boneschi; M Filippi; Francesco Patti; Arturo Reggio; Diego Franciotta; L Allegra; G Comi; F Blasi
An MRI study of Chlamydia pneumoniae infection in Italian multiple sclerosis patients.
Multiple sclerosis (Houndmills, Basingstoke, England) 2003;9(5):467-71.
2003: Letizia Scola; Federico Licastro; Martina Chiappelli; Claudio Franceschi; Luigi M E Grimaldi; Antonio Crivello; Giuseppina Colonna-Romano; Giuseppina Candore; Domenico Lio; Calogero Caruso
Allele frequencies of +874T --> A single nucleotide polymorphism at the first intron of IFN-gamma gene in Alzheimer's disease patients.
Aging clinical and experimental research 2003;15(4):292-5.
2003: Innocenzo Rainero; Giuliana Salani; Walter Valfrè; Lidia Savi; Chiara Rivoiro; Margherita Ferrero; Lorenzo Pinessi; Luigi M E Grimaldi
Absence of linkage between the interleukin-6 gene (-174 G/C) polymorphism and migraine.
Neuroscience letters 2003;343(3):155-8.
2003: M Axel Wollmer; Johannes R Streffer; Magdalini Tsolaki; Luigi M E Grimaldi; Dieter Lütjohann; Dietmar R Thal; K von Bergmann; Roger M Nitsch; Christoph Hock; Andreas Papassotiropoulos
Genetic association of acyl-coenzyme A: cholesterol acyltransferase with cerebrospinal fluid cholesterol levels, brain amyloid load, and risk for Alzheimer's disease.
Molecular psychiatry 2003;8(6):635-8.
2003: Luca Cavallone; Massimiliano Bonafè; Fabiola Olivieri; Maurizio Cardelli; Francesca Marchegiani; Simona Giovagnetti; Grazia Di Stasio; Claudia Giampieri; Elena Mugianesi; Rosalia Stecconi; Francesca Sciacca; Luigi M E Grimaldi; Giovanna De Benedictis; Domenico Lio; Calogero Caruso; Claudio Franceschi
The role of IL-1 gene cluster in longevity: a study in Italian population.
Mechanisms of ageing and development 2003;124(4):533-8.
2003: Giuseppina Candore; Federico Licastro; Martina Chiappelli; Claudio Franceschi; Domenico Lio; Carmela Rita Balistreri; Giuseppina Piazza; Giuseppina Colonna-Romano; Luigi M E Grimaldi; Calogero Caruso
Association between the HFE mutations and unsuccessful ageing: a study in Alzheimer's disease patients from Northern Italy.
Mechanisms of ageing and development 2003;124(4):525-8.
2003: Domenico Lio; Federico Licastro; Letizia Scola; Martina Chiappelli; Luigi M E Grimaldi; Antonio Crivello; Giuseppina Colonna-Romano; Giuseppina Candore; Claudio Franceschi; Calogero Caruso
Interleukin-10 promoter polymorphism in sporadic Alzheimer's disease.
Genes and immunity 2003;4(3):234-8.
2002: Roberto Dominici; Giulia Malferrari; Claudio Mariani; Luigi M E Grimaldi; Ida Biunno
The Interleukin 1-beta exonic (+3953) polymorphism does not alter in vitro protein secretion.
Experimental and molecular pathology 2002;73(2):139-41.
2002: M Axel Wollmer; Andreas Papassotiropoulos; Johannes R Streffer; Luigi M E Grimaldi; Elisabeth Kapaki; Giuliana Salani; George P Paraskevas; Alessia Maddalena; Dominique J-F de Quervain; Claudia Bieber; Daniel Umbricht; Ulrike Lemke; Simone Bosshardt; Nadia Degonda; Katharina Henke; Thomas Hegi; Hans H Jung; Thomas Pasch; Christoph Hock; Roger M Nitsch
Genetic polymorphisms and cerebrospinal fluid levels of tissue inhibitor of metalloproteinases 1 in sporadic Alzheimer's disease.
Psychiatric genetics 2002;12(3):155-60.
2002: Innocenzo Rainero; Lorenzo Pinessi; Giuliana Salani; Walter Valfrè; Chiara Rivoiro; Lidia Savi; Salvatore Gentile; Rossana Lo Giudice; Luigi M E Grimaldi
A polymorphism in the interleukin-1alpha gene influences the clinical features of migraine.
Headache 2002;42(5):337-40.
2002: Roberto Dominici; Monica Cattaneo; Giulia Malferrari; Davide Archi; Claudio Mariani; Luigi M E Grimaldi; Ida Biunno
Cloning and functional analysis of the allelic polymorphism in the transcription regulatory region of interleukin-1 alpha.
Immunogenetics 2002;54(2):82-6.
2002: Innocenzo Rainero; Luigi M E Grimaldi; Giuliana Salani; Walter Valfrè; Lidia Savi; Chiara Rivoiro; Salvatore Gentile; Lorenzo Pinessi
Apolipoprotein E gene polymorphisms in patients with migraine.
Neuroscience letters 2002;317(2):111-3.
2002: Francesca L Sciacca; Cinzia Ferri; Fabrizio Veglia; Francesca Andreetta; Renato Mantegazza; Ferdinando Cornelio; Diego Franciotta; Giovanni Piccolo; Vittorio Cosi; Anna Paola Batocchi; Amelia Evoli; Luigi M E Grimaldi
IL-1 genes in myasthenia gravis: IL-1A -889 polymorphism associated with sex and age of disease onset.
Journal of neuroimmunology 2002;122(1-2):94-9.
2001: VM Casadei; C Ferri; Elena Calabrese; Luigi M E Grimaldi; M Franceschi; F Veglia; F Licastro; Claudio Mariani
Prion protein gene polymorphism and Alzheimer's disease: one modulatory trait of cognitive decline?
Journal of neurology, neurosurgery, and psychiatry 2001;71(2):279-80.
2000: C Ferri; Francesca L Sciacca; L E Grimaldi; F Veglia; G Magnani; Giuseppe Santuccio; Giancarlo Comi; Nicola Canal; Luigi M E Grimaldi
Lack of association between IL-1A and IL-1B promoter polymorphisms and multiple sclerosis.
Journal of neurology, neurosurgery, and psychiatry 2000;69(4):564-5.
2000: Federico Licastro; S Pedrini; Cinzia Ferri; VM Casadei; Marzia Govoni; Andrea Pession; Francesca L Sciacca; Fabrizio Veglia; Giorgio Annoni; M Bonafè; Fabiola Olivieri; C Franceschi; Luigi M E Grimaldi
Gene polymorphism affecting alpha1-antichymotrypsin and interleukin-1 plasma levels increases Alzheimer's disease risk.
Annals of neurology 2000;48(3):388-91.
2000: Francesca L Sciacca; Nicola Canal; Luigi M E Grimaldi
Induction of IL-1 receptor antagonist by interferon beta: implication for the treatment of multiple sclerosis.
Journal of neurovirology 2000;6 Suppl 2():S33-7.
2000: Francesca L Sciacca; Cinzia Ferri; Sandra D'Alfonso; Elisabetta Bolognesi; Filippo Martinelli Boneschi; B Cuzzilla; Bruno Colombo; Giancarlo Comi; Nicola Canal; Luigi M E Grimaldi
Association study of a new polymorphism in the PECAM-1 gene in multiple sclerosis.
Journal of neuroimmunology 2000;104(2):174-8.
2000: Luigi M E Grimaldi; VM Casadei; Cinzia Ferri; Fabrizio Veglia; Federico Licastro; Giorgio Annoni; Ida Biunno; De Bellis Gianluca; Sandro Sorbi; Claudio Mariani; Nicola Canal; W Sue T Griffin; M Franceschi
Association of early-onset Alzheimer's disease with an interleukin-1alpha gene polymorphism.
Annals of neurology 2000;47(3):361-5.
2000: Federico Licastro; S Pedrini; L Caputo; Giorgio Annoni; LJ Davis; Cinzia Ferri; VM Casadei; Luigi M E Grimaldi
Increased plasma levels of interleukin-1, interleukin-6 and alpha-1-antichymotrypsin in patients with Alzheimer's disease: peripheral inflammation or signals from the brain?
Journal of neuroimmunology 2000;103(1):97-102.
2000: Koen Vandenbroeck; Cornelia Hardt; J Louage; Pierre Fiten; S Jäckel; Isabelle Ronsse; Jörg T Epplen; Luigi M E Grimaldi; Tomas Olsson; Maria Giovanna Marrosu; An D Billiau; Ghislain Opdenakker
Lack of association between the interferon regulatory factor-1 (IRF1) locus at 5q31.1 and multiple sclerosis in Germany, northern Italy, Sardinia and Sweden.
Genes and immunity 2000;1(4):290-2.
1999: VM Casadei; Cinzia Ferri; Fabrizio Veglia; A Gavazzi; Giuliana Salani; M Cattaneo; Sandro Sorbi; Giorgio Annoni; Federico Licastro; Claudio Mariani; M Franceschi; Luigi M E Grimaldi
APOE-491 promoter polymorphism is a risk factor for late-onset Alzheimer's disease.
Neurology 1999;53(8):1888-9.
1999: Prisco Mirandola; Alessandra Stefan; E Brambilla; Gabriella Campadelli-Fiume; Luigi M E Grimaldi
Absence of human herpesvirus 6 and 7 from spinal fluid and serum of multiple sclerosis patients.
Neurology 1999;53(6):1367-8.
1999: Cinzia Ferri; Francesca L Sciacca; Fabrizio Veglia; F Martinelli; Giancarlo Comi; Nicola Canal; Luigi M E Grimaldi
APOE epsilon2-4 and -491 polymorphisms are not associated with MS.
Neurology 1999;53(4):888-9.
1999: An Goris; C Epplen; Pierre Fiten; M Andersson; Raffaele Murru; Francesca L Sciacca; Isabelle Ronsse; S Jäckel; Jörg T Epplen; Maria Giovanna Marrosu; Tomas Olsson; Luigi M E Grimaldi; Ghislain Opdenakker; An D Billiau; Koen Vandenbroeck
Analysis of an IFN-gamma gene (IFNG) polymorphism in multiple sclerosis in Europe: effect of population structure on association with disease.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 1999;19(9):1037-46.
1999: Federico Licastro; S Pedrini; Marzia Govoni; Andrea Pession; Cinzia Ferri; Giorgio Annoni; VM Casadei; Fabrizio Veglia; S Bertolini; Luigi M E Grimaldi
Apolipoprotein E and alpha-1-antichymotrypsin allele polymorphism in sporadic and familial Alzheimer's disease.
Neuroscience letters 1999;270(3):129-32.
1999: Francesca L Sciacca; Cinzia Ferri; Koen Vandenbroeck; Fabrizio Veglia; C Gobbi; F Martinelli; Diego Franciotta; Mauro Zaffaroni; Maria Giovanna Marrosu; Gianvito Martino; Vittorio Martinelli; Giancarlo Comi; Nicola Canal; Luigi M E Grimaldi
Relevance of interleukin 1 receptor antagonist intron 2 polymorphism in Italian MS patients.
Neurology 1999;52(9):1896-8.
1998: Gianvito Martino; Fabio Grohovaz; E Brambilla; Franca Codazzi; Anna Lange Consiglio; E Clementi; Massimo Filippi; Giancarlo Comi; Luigi M E Grimaldi
Proinflammatory cytokines regulate antigen-independent T-cell activation by two separate calcium-signaling pathways in multiple sclerosis patients.
Annals of neurology 1998;43(3):340-9.
1997: Gianvito Martino; Anna Lange Consiglio; Diego Franciotta; A Corti; Massimo Filippi; Koen Vandenbroeck; Francesca L Sciacca; Giancarlo Comi; Luigi M E Grimaldi
Tumor necrosis factor alpha and its receptors in relapsing-remitting multiple sclerosis.
Journal of the neurological sciences 1997;152(1):51-61.
1997: Gianvito Martino; M Filippi; Vittorio Martinelli; E Brambilla; C Gobbi; Giancarlo Comi; Luigi M E Grimaldi
Interferon-gamma induced increases in intracellular calcium in T lymphocytes from patients with multiple sclerosis precede clinical exacerbations and detection of active lesions on MRI.
Journal of neurology, neurosurgery, and psychiatry 1997;63(3):339-45.
1997: Koen Vandenbroeck; Gianvito Martino; Maria Giovanna Marrosu; Anna Lange Consiglio; Mauro Zaffaroni; S Vaccargiu; Diego Franciotta; M Ruggeri; Giancarlo Comi; Luigi M E Grimaldi
Occurrence and clinical relevance of an interleukin-4 gene polymorphism in patients with multiple sclerosis.
Journal of neuroimmunology 1997;76(1-2):189-92.