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Elizabeth Grimm

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Disorders

Chemicals & Drugs

Anatomy

Physiology

Genes & Molecular Sequences

Genes, Tumor Suppressor

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Xiaoxiang Guan; Jeffrey E Lee; Zhensheng Liu; Jiangong Niu; Li-E Wang; Christopher I Amos; Jeffrey E Gershenwald; Elizabeth A Grimm; Qingyi Wei
Variants in melanocortin 1 receptor gene contribute to risk of melanoma--a direct sequencing analysis in a Texas population.
Yong Qin; Wuguo Deng; Suhendan Ekmekcioglu; Elizabeth A Grimm
Identification of unique sensitizing targets for anti-inflammatory CDDO-Me in metastatic melanoma by a large-scale synthetic lethal RNAi screening.
Keiji Tanese; Elizabeth A Grimm; Suhendan Ekmekcioglu
The role of melanoma tumor-derived nitric oxide in the tumor inflammatory microenvironment: its impact on the chemokine expression profile, including suppression of CXCL10.

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2013: Xiaoxiang Guan; Jeffrey E Lee; Zhensheng Liu; Jiangong Niu; Li-E Wang; Christopher I Amos; Jeffrey E Gershenwald; Elizabeth A Grimm; Qingyi Wei
Variants in melanocortin 1 receptor gene contribute to risk of melanoma--a direct sequencing analysis in a Texas population.
Pigment cell & melanoma research 2013;26(3):422-5.
2013: Yong Qin; Wuguo Deng; Suhendan Ekmekcioglu; Elizabeth A Grimm
Identification of unique sensitizing targets for anti-inflammatory CDDO-Me in metastatic melanoma by a large-scale synthetic lethal RNAi screening.
Pigment cell & melanoma research 2013;26(1):97-112.
2012: Keiji Tanese; Elizabeth A Grimm; Suhendan Ekmekcioglu
The role of melanoma tumor-derived nitric oxide in the tumor inflammatory microenvironment: its impact on the chemokine expression profile, including suppression of CXCL10.
International journal of cancer. Journal international du cancer 2012;131(4):891-901.
2012: Chandrani Chattopadhyay; Michael A Davies; Suhendan Ekmekcioglu; Julie A Ellerhorst; Victoria R Greene; Elizabeth A Grimm
Association of activated c-Met with NRAS-mutated human melanomas.
International journal of cancer. Journal international du cancer 2012;131(2):E56-65.
2012: Hongliang Liu; Victor G Prieto; Qingyi Wei; Madeleine Duvic; Jeffrey E Gershenwald; Elizabeth A Grimm; Jeffrey E Lee; Li-E Wang
Influence of single nucleotide polymorphisms in the MMP1 promoter region on cutaneous melanoma progression.
Melanoma research 2012;22(2):169-75.
2012: Ian Lee; Christopher W Schacherer; Ling-Yuan Kong; Roland Bassett; Sherise D Ferguson; Patricia S Fox; Gregory N Fuller; jeffrey gershenwald; Elizabeth A Grimm; Amy B Heimberger
The expression of p-STAT3 in stage IV melanoma: risk of CNS metastasis and survival.
Oncotarget 2012;3(3):336-44.
2012: Charles Lu; John D McMannis; Maria I Nunez; Rajagopal Ramesh; James M Reuben; Veerabhadran Baladandayuthapani; Jeremy J Erasmus; Elizabeth A Grimm; Marshall E Hicks; Gitanjali Jayachandran; Lin Ji; J Jack Lee; David J Stewart; Nancy S Templeton; Ignacio I Wistuba; Jack A Roth
Phase I clinical trial of systemically administered TUSC2(FUS1)-nanoparticles mediating functional gene transfer in humans.
PloS one 2012;7(4):e34833.
2011: Yong Qin; Lyn M Duncan; Suhendan Ekmekcioglu; Ping Liu; Gregory Lizée; Nancy J Poindexter; Elizabeth A Grimm
Constitutive aberrant endogenous interleukin-1 facilitates inflammation and growth in human melanoma.
Molecular cancer research : MCR 2011;9(11):1537-50.
2011: Julie A Ellerhorst; Victoria R Greene; Suhendan Ekmekcioglu; Carla L Warneke; Marcella M Johnson; Carolyn P Cooke; Li-E Wang; Victor G Prieto; jeffrey gershenwald; Qingyi Wei; Elizabeth A Grimm
Clinical correlates of NRAS and BRAF mutations in primary human melanoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2011;17(2):229-35.
2011: Manish Shanker; Jiankang Jin; Cynthia D Branch; Shinya Miyamoto; Elizabeth A Grimm; Jack A Roth; Rajagopal Ramesh
Tumor suppressor gene-based nanotherapy: from test tube to the clinic.
Journal of drug delivery 2011;2011():465845.
2011: Li-E Wang; Yu-jing Huang; Ming Yin; Jeffrey E Gershenwald; Victor G Prieto; Jeffrey E Lee; Madeleine Duvic; Elizabeth A Grimm; Qingyi Wei
Promoter polymorphisms in matrix metallopeptidase 1 and risk of cutaneous melanoma.
European journal of cancer (Oxford, England : 1990) 2011;47(1):107-15.
2010: Nancy J Poindexter; Ryan R Williams; Garth Powis; Emily Jen; Abigail S Caudle; Sunil Chada; Elizabeth A Grimm
IL-24 is expressed during wound repair and inhibits TGFalpha-induced migration and proliferation of keratinocytes.
Experimental dermatology 2010;19(8):714-22.
2010: Julie A Ellerhorst; A Hafeez Diwan; Shyam M Dang; Deon G Uffort; Marilyn K Johnson; Carolyn P Cooke; Elizabeth A Grimm
Promotion of melanoma growth by the metabolic hormone leptin.
Oncology reports 2010;23(4):901-7.
2009: Victoria R Greene; Marcella M Johnson; Elizabeth A Grimm; Julie A Ellerhorst
Frequencies of NRAS and BRAF mutations increase from the radial to the vertical growth phase in cutaneous melanoma.
The Journal of investigative dermatology 2009;129(6):1483-8.
2009: Ghazal I Zafar; Elizabeth A Grimm; Wei Wei; Marcella M Johnson; Julie A Ellerhorst
Genetic deficiency of complement isoforms C4A or C4B predicts improved survival of metastatic renal cell carcinoma.
The Journal of urology 2009;181(3):1028-34; discussion 1034.
2008: Chunying Li; Hui Zhao; Zhibin Hu; Zhensheng Liu; Li-E Wang; jeffrey gershenwald; Victor G Prieto; Jeffrey E Lee; Madeleine Duvic; Elizabeth A Grimm; Qingyi Wei
Genetic variants and haplotypes of the caspase-8 and caspase-10 genes contribute to susceptibility to cutaneous melanoma.
Human mutation 2008;29(12):1443-51.
2008: Ling-Yuan Kong; Mohamed K Abou-Ghazal; Jun Wei; Arup Chakraborty; Wei Sun; Wei Qiao; Gregory N Fuller; Izabela Fokt; Elizabeth A Grimm; Robert J Schmittling; Gary E Archer; John H Sampson; Waldemar Priebe; Amy B Heimberger
A novel inhibitor of signal transducers and activators of transcription 3 activation is efficacious against established central nervous system melanoma and inhibits regulatory T cells.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(18):5759-68.
2008: Elizabeth A Grimm; Julie A Ellerhorst; Chi-Hui Tang; Suhendan Ekmekcioglu
Constitutive intracellular production of iNOS and NO in human melanoma: possible role in regulation of growth and resistance to apoptosis.
Nitric oxide : biology and chemistry / official journal of the Nitric Oxide Society 2008;19(2):133-7.
2008: Cindy S Hwang; Victor G Prieto; Abdul H Diwan; Gregory Lizee; Julie A Ellerhorst; Suhendan Ekmekcioglu; Ping Liu; Omar Eton; Sandra A Kinney; Elizabeth A Grimm; Patrick Hwu; Kevin B Kim
Changes in pERK1/2 and pAKT expression in melanoma lesions after imatinib treatment.
Melanoma research 2008;18(4):241-5.
2008: Suhendan Ekmekcioglu; John B Mumm; Malini Udtha; Sunil Chada; Elizabeth A Grimm
Killing of human melanoma cells induced by activation of class I interferon-regulated signaling pathways via MDA-7/IL-24.
Cytokine 2008;43(1):34-44.
2008: Chunying Li; Zhensheng Liu; Li-E Wang; jeffrey gershenwald; Jeffrey E Lee; Victor G Prieto; Madeleine Duvic; Elizabeth A Grimm; Qingyi Wei
Haplotype and genotypes of the VDR gene and cutaneous melanoma risk in non-Hispanic whites in Texas: a case-control study.
International journal of cancer. Journal international du cancer 2008;122(9):2077-84.
2007: Mingzhong Zheng; Waldemar Priebe; Eugene T Walch; Katherine G Roth; Mikyung Han; Chi-Hui Tang; Sangkyou Lee; Nancy J Poindexter; Izabela Fokt; Elizabeth A Grimm
WP760, a melanoma selective drug.
Cancer chemotherapy and pharmacology 2007;60(5):625-33.
2007: Chunying Li; Zhibin Hu; Zhensheng Liu; Li-E Wang; jeffrey gershenwald; Jeffrey E Lee; Victor G Prieto; Madeleine Duvic; Elizabeth A Grimm; Qingyi Wei
Polymorphisms of the neuronal and inducible nitric oxide synthase genes and the risk of cutaneous melanoma: a case-control study.
Cancer 2007;109(8):1570-8.
2007: Chunying Li; Zhensheng Liu; Zhengdong Zhang; Sara S Strom; jeffrey gershenwald; Victor G Prieto; Jeffrey E Lee; Merrick I Ross; Paul F Mansfield; Janice N Cormier; Madeleine Duvic; Elizabeth A Grimm; Qingyi Wei
Genetic variants of the vitamin D receptor gene alter risk of cutaneous melanoma.
The Journal of investigative dermatology 2007;127(2):276-80.
2007: Mingzhong Zheng; Dora Bocangel; Blair Doneske; Abner M Mhashilkar; Rajagopal Ramesh; Kelly K Hunt; Suhendan Ekmekcioglu; R Bryan Sutton; Nancy J Poindexter; Elizabeth A Grimm; Sunil Chada
Human interleukin 24 (MDA-7/IL-24) protein kills breast cancer cells via the IL-20 receptor and is antagonized by IL-10.
Cancer immunology, immunotherapy : CII 2007;56(2):205-15.
2006: John B Mumm; Suhendan Ekmekcioglu; Nancy J Poindexter; Sunil Chada; Elizabeth A Grimm
Soluble human MDA-7/IL-24: characterization of the molecular form(s) inhibiting tumor growth and stimulating monocytes.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2006;26(12):877-86.
2006: Chunying Li; Zhibin Hu; Zhensheng Liu; Li-E Wang; Sara S Strom; jeffrey gershenwald; Jeffrey E Lee; Merrick I Ross; Paul F Mansfield; Janice N Cormier; Victor G Prieto; Madeleine Duvic; Elizabeth A Grimm; Qingyi Wei
Polymorphisms in the DNA repair genes XPC, XPD, and XPG and risk of cutaneous melanoma: a case-control analysis.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2006;15(12):2526-32.
2006: Chunying Li; Zhensheng Liu; Li-E Wang; Sara S Strom; Jeffrey E Lee; jeffrey gershenwald; Merrick I Ross; Paul F Mansfield; Janice N Cormier; Victor G Prieto; Madeleine Duvic; Elizabeth A Grimm; Qingyi Wei
Genetic variants of the ADPRT, XRCC1 and APE1 genes and risk of cutaneous melanoma.
Carcinogenesis 2006;27(9):1894-901.
2006: Suhendan Ekmekcioglu; Julie A Ellerhorst; Victor G Prieto; Marcella M Johnson; Lyle D Broemeling; Elizabeth A Grimm
Tumor iNOS predicts poor survival for stage III melanoma patients.
International journal of cancer. Journal international du cancer 2006;119(4):861-6.
2006: Chunying Li; Derek Larson; Zhengdong Zhang; Zhensheng Liu; Sara S Strom; jeffrey gershenwald; Victor G Prieto; Jeffrey E Lee; Merrick I Ross; Paul F Mansfield; Janice N Cormier; Madeleine Duvic; Elizabeth A Grimm; Qingyi Wei
Polymorphisms of the FAS and FAS ligand genes associated with risk of cutaneous malignant melanoma.
Pharmacogenetics and genomics 2006;16(4):253-63.
2005: Nancy J Poindexter; Eugene T Walch; Sunil Chada; Elizabeth A Grimm
Cytokine induction of interleukin-24 in human peripheral blood mononuclear cells.
Journal of leukocyte biology 2005;78(3):745-52.
2005: Sunil Chada; Dora Bocangel; Rajagopal Ramesh; Elizabeth A Grimm; John B Mumm; Abner M Mhashilkar; Mingzhong Zheng
mda-7/IL24 kills pancreatic cancer cells by inhibition of the Wnt/PI3K signaling pathways: identification of IL-20 receptor-mediated bystander activity against pancreatic cancer.
Molecular therapy : the journal of the American Society of Gene Therapy 2005;11(5):724-33.
2005: Suhendan Ekmekcioglu; Chi-Hui Tang; Elizabeth A Grimm
NO news is not necessarily good news in cancer.
Current cancer drug targets 2005;5(2):103-15.
2005: Alex W Tong; John Nemunaitis; Dan Su; Yuan Zhang; Casey Cunningham; Neil Senzer; GEORGES NETTO; Dawn Rich; Abner M Mhashilkar; Karen Parker; Keith Coffee; Rajagopal Ramesh; Suhendan Ekmekcioglu; Elizabeth A Grimm; Jill van Wart Hood; James Merritt; Sunil Chada
Intratumoral injection of INGN 241, a nonreplicating adenovector expressing the melanoma-differentiation associated gene-7 (mda-7/IL24): biologic outcome in advanced cancer patients.
Molecular therapy : the journal of the American Society of Gene Therapy 2005;11(1):160-72.
2004: Sunil Chada; Abner M Mhashilkar; Rajagopal Ramesh; John B Mumm; R Bryan Sutton; Dora Bocangel; Mingzhong Zheng; Elizabeth A Grimm; Suhendan Ekmekcioglu
Bystander activity of Ad-mda7: human MDA-7 protein kills melanoma cells via an IL-20 receptor-dependent but STAT3-independent mechanism.
Molecular therapy : the journal of the American Society of Gene Therapy 2004;10(6):1085-95.
2004: Julie A Ellerhorst; William H Hildebrand; Joshua W Cavett; Marcelo Fernandez-Vina; Sherie Hodges; Nancy J Poindexter; H Fischer; Elizabeth A Grimm
HLA class II haplotypes predict favorable outcomes for patients with metastatic RCC.
Der Urologe. Ausg. A 2004;43 Suppl 3():S137.
2004: Julie A Ellerhorst; Aresu Naderi; Marilyn K Johnson; Pauline Pelletier; Victor G Prieto; A Hafeez Diwan; Marcella M Johnson; Debra C Gunn; Sandra Yekell; Elizabeth A Grimm
Expression of thyrotropin-releasing hormone by human melanoma and nevi.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(16):5531-6.
2004: Kevin B Kim; Omar Eton; Mary Jo East; Cynthia Hodges; Nicholas E Papadopoulos; Elizabeth A Grimm; Agop Bedikian
Pilot study of high-dose, concurrent biochemotherapy for advanced melanoma.
Cancer 2004;101(3):596-603.
2004: Mingzhong Zheng; Suhendan Ekmekcioglu; Eugene T Walch; Chi-Hui Tang; Elizabeth A Grimm
Inhibition of nuclear factor-kappaB and nitric oxide by curcumin induces G2/M cell cycle arrest and apoptosis in human melanoma cells.
Melanoma research 2004;14(3):165-71.
2004: Sunil Chada; R Bryan Sutton; Suhendan Ekmekcioglu; Julie A Ellerhorst; John B Mumm; Wolfgang W Leitner; Heng-Yin Yang; Aysegul A Sahin; Kelly K Hunt; Kerry L Fuson; Nancy Poìndexter; Jack A Roth; Rajagopal Ramesh; Elizabeth A Grimm; Abner M Mhashilkar
MDA-7/IL-24 is a unique cytokine--tumor suppressor in the IL-10 family.
International immunopharmacology 2004;4(5):649-67.
2004: Kerry Sieger; Abner M Mhashilkar; Alexis Stewart; R Bryan Sutton; Randall W Strube; Si-Yi Chen; Abujiang Pataer; Stephen G Swisher; Elizabeth A Grimm; Rajagopal Ramesh; Sunil Chada
The tumor suppressor activity of MDA-7/IL-24 is mediated by intracellular protein expression in NSCLC cells.
Molecular therapy : the journal of the American Society of Gene Therapy 2004;9(3):355-67.
2004: Nancy J Poindexter; Aysegul Sahin; Kelly K Hunt; Elizabeth A Grimm
Analysis of dendritic cells in tumor-free and tumor-containing sentinel lymph nodes from patients with breast cancer.
Breast cancer research : BCR 2004;6(4):R408-15.
2003: Julie A Ellerhorst; Catherine Cooksley; Lyle D Broemeling; Marcella M Johnson; Elizabeth A Grimm
High prevalence of hypothyroidism among patients with cutaneous melanoma.
Oncology reports 2003;10(5):1317-20.
2003: Rajagopal Ramesh; Abner M Mhashilkar; Fumihiro Tanaka; Yuji Saito; Cynthia D Branch; Kerry Sieger; John B Mumm; Alexis L Stewart; Amelie Boquoi; Laure Dumoutier; Elizabeth A Grimm; Jean-Christophe Renauld; Sergei V Kotenko; Sunil Chada; Amelia Boquio
Melanoma differentiation-associated gene 7/interleukin (IL)-24 is a novel ligand that regulates angiogenesis via the IL-22 receptor.
Cancer research 2003;63(16):5105-13.
2003: Abner M Mhashilkar; Alexis L Stewart; Kerry Sieger; Heng-Yin Yang; Anis H Khimani; Isao Ito; Yuji Saito; Kelly K Hunt; Elizabeth A Grimm; Jack A Roth; Raymond E Meyn; Rajagopal Ramesh; Sunil Chada
MDA-7 negatively regulates the beta-catenin and PI3K signaling pathways in breast and lung tumor cells.
Molecular therapy : the journal of the American Society of Gene Therapy 2003;8(2):207-19.
2003: Julie A Ellerhorst; William H Hildebrand; Joshua W Cavett; Marcelo Fernandez-Vina; Sherie Hodges; Nancy J Poindexter; Harald Fischer; Elizabeth A Grimm
Heterozygosity or homozygosity for 2 HLA class II haplotypes predict favorable outcomes for renal cell carcinoma treated with cytokine therapy.
The Journal of urology 2003;169(6):2084-8.
2003: Suhendan Ekmekcioglu; Julie A Ellerhorst; John B Mumm; Mingzhong Zheng; Lyle D Broemeling; Victor G Prieto; Alexis L Stewart; Abner M Mhashilkar; Sunil Chada; Elizabeth A Grimm
Negative association of melanoma differentiation-associated gene (mda-7) and inducible nitric oxide synthase (iNOS) in human melanoma: MDA-7 regulates iNOS expression in melanoma cells.
Molecular cancer therapeutics 2003;2(1):9-17.
2002: Ann-Marie Simeone; Suhendan Ekmekcioglu; Lyle D Broemeling; Elizabeth A Grimm; Ana M Tari
A novel mechanism by which N-(4-hydroxyphenyl)retinamide inhibits breast cancer cell growth: the production of nitric oxide.
Molecular cancer therapeutics 2002;1(12):1009-17.
2002: Alexis L Stewart; Abner M Mhashilkar; XIAOHONG YANG; Suhendan Ekmekcioglu; Yuji Saito; Kerry Sieger; Robert Schrock; Eric Onishi; Xin Swanson; John B Mumm; Louis Zumstein; Graham J Watson; David Snary; Jack A Roth; Elizabeth A Grimm; Rajagopal Ramesh; Sunil Chada
PI3 kinase blockade by Ad-PTEN inhibits invasion and induces apoptosis in RGP and metastatic melanoma cells.
Molecular medicine (Cambridge, Mass.) 2002;8(8):451-61.
2002: Jeffrey E Lee; Joseph Abdalla; Geoffrey A Porter; Loretta Bradford; Elizabeth A Grimm; John D Reveille; Paul F Mansfield; jeffrey gershenwald; Merrick I Ross
Presence of the human leukocyte antigen class II gene DRB1*1101 predicts interferon gamma levels and disease recurrence in melanoma patients.
Annals of surgical oncology 2002;9(6):587-93.
2002: Eva G Caudell; John B Mumm; Nancy J Poindexter; Suhendan Ekmekcioglu; Abner M Mhashilkar; XIAOHONG YANG; Mark W Retter; Paul Hill; Sunil Chada; Elizabeth A Grimm
The protein product of the tumor suppressor gene, melanoma differentiation-associated gene 7, exhibits immunostimulatory activity and is designated IL-24.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(12):6041-6.
2002: Julie A Ellerhorst; Victor G Prieto; Suhendan Ekmekcioglu; Lyle D Broemeling; Sandra Yekell; Sunil Chada; Elizabeth A Grimm
Loss of MDA-7 expression with progression of melanoma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2002;20(4):1069-74.
2001: Julie A Ellerhorst; Catherine Cooksley; Elizabeth A Grimm
Autoimmunity and hypothyroidism in patients with uveal melanoma.
Melanoma research 2001;11(6):633-7.
2001: Suhendan Ekmekcioglu; Julie A Ellerhorst; Abner M Mhashilkar; Aysegul A Sahin; C M Read; Victor G Prieto; Sunil Chada; Elizabeth A Grimm
Down-regulated melanoma differentiation associated gene (mda-7) expression in human melanomas.
International journal of cancer. Journal international du cancer 2001;94(1):54-9.
2001: Satish K Mehta; I Kaur; Elizabeth A Grimm; CM Smid; DL Feeback; Duane L Pierson
Decreased non-MHC-restricted (CD56+) killer cell cytotoxicity after spaceflight.
Journal of applied physiology (Bethesda, Md. : 1985) 2001;91(4):1814-8.
2001: Geoffrey A Porter; J Abdalla; M Lu; S Smith; D Montgomery; Elizabeth A Grimm; Merrick I Ross; Paul F Mansfield; jeffrey gershenwald; Jeffrey E Lee
Significance of plasma cytokine levels in melanoma patients with histologically negative sentinel lymph nodes.
Annals of surgical oncology 2001;8(2):116-22.
2000: Suhendan Ekmekcioglu; Julie A Ellerhorst; CM Smid; Victor G Prieto; M Munsell; Antonio C Buzaid; Elizabeth A Grimm
Inducible nitric oxide synthase and nitrotyrosine in human metastatic melanoma tumors correlate with poor survival.
Clinical cancer research : an official journal of the American Association for Cancer Research 2000;6(12):4768-75.
2000: Eva G Caudell; Jimmy J Caudell; C H Tang; Tse-Kuan Yu; Mitchell J Frederick; Elizabeth A Grimm
Characterization of human copine III as a phosphoprotein with associated kinase activity.
Biochemistry 2000;39(42):13034-43.
2000: Elizabeth A Grimm; CM Smid; J Jack Lee; C H Tseng; Omar Eton; Antonio C Buzaid
Unexpected cytokines in serum of malignant melanoma patients during sequential biochemotherapy.
Clinical cancer research : an official journal of the American Association for Cancer Research 2000;6(10):3895-903.
2000: Tse-Kuan Yu; Eva G Caudell; CM Smid; Elizabeth A Grimm
IL-2 activation of NK cells: involvement of MKK1/2/ERK but not p38 kinase pathway.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(12):6244-51.
1999: L L Licato; Elizabeth A Grimm
Multiple interleukin-2 signaling pathways differentially regulated by microgravity.
Immunopharmacology 1999;44(3):273-9.
1999: Suhendan Ekmekcioglu; M Fatih Okcu; MI Colome-Grimmer; Laurie B Owen-Schaub; Antonio C Buzaid; Elizabeth A Grimm
Differential increase of Fas ligand expression on metastatic and thin or thick primary melanoma cells compared with interleukin-10.
Melanoma research 1999;9(3):261-72.
1998: EK Robinson; N Sneige; Elizabeth A Grimm
Correlation of interleukin 6 with interleukin 1alpha in human mammary tumours, but not with oestrogen receptor expression.
Cytokine 1998;10(12):970-6.
1998: KV Woods; Karen Adler-Storthz; Gary L Clayman; G M Francis; Elizabeth A Grimm
Interleukin-1 regulates interleukin-6 secretion in human oral squamous cell carcinoma in vitro: possible influence of p53 but not human papillomavirus E6/E7.
Cancer research 1998;58(14):3142-9.
1998: KV Woods; Adel El-Naggar; Gary L Clayman; Elizabeth A Grimm
Variable expression of cytokines in human head and neck squamous cell carcinoma cell lines and consistent expression in surgical specimens.
Cancer research 1998;58(14):3132-41.
1998: EK Robinson; Ana M Grau; Douglas B Evans; CM Smid; Paul J Chiao; James L Abbruzzese; Elizabeth A Grimm
Cell cycle regulation of human pancreatic cancer by tamoxifen.
Annals of surgical oncology 1998;5(4):342-9.
1998: C M Anderson; Antonio C Buzaid; J Sussman; J Jack Lee; Francis Ali-Osman; Paul Braunschweiger; Carl Plager; Agop Bedikian; Nicholas Papadopoulos; Omar Eton; Sewa S Legha; Elizabeth A Grimm
Nitric oxide and neopterin levels and clinical response in stage III melanoma patients receiving concurrent biochemotherapy.
Melanoma research 1998;8(2):149-55.
1998: Antonio C Buzaid; Francis Ali-Osman; N Akande; Elizabeth A Grimm; J Jack Lee; Agop Bedikian; Omar Eton; Nicholas Papadopoulos; Carl Plager; Sewa S Legha; Robert S Benjamin
DNA damage in peripheral blood mononuclear cells correlates with response to biochemotherapy in melanoma.
Melanoma research 1998;8(2):145-8.
1998: Michael Bouvet; Bingliang Fang; Suhendan Ekmekcioglu; L Ji; C D Bucana; K Hamada; Elizabeth A Grimm; Jack A Roth
Suppression of the immune response to an adenovirus vector and enhancement of intratumoral transgene expression by low-dose etoposide.
Gene therapy 1998;5(2):189-95.
1997: Mitchell J Frederick; Elizabeth A Grimm; E Krohn; CM Smid; Tse-Kuan Yu
Cytokine-induced cytotoxic function expressed by lymphocytes of the innate immune system: distinguishing characteristics of NK and LAK based on functional and molecular markers.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 1997;17(8):435-47.
1997: F A Jung; Antonio C Buzaid; Merrick I Ross; KV Woods; J Jack Lee; Maher Albitar; Elizabeth A Grimm
Evaluation of tyrosinase mRNA as a tumor marker in the blood of melanoma patients.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1997;15(8):2826-31.
1997: Sekhar M Pothireddy; R M Harwood; D F Moore; Elizabeth A Grimm; James L Murray; Saroj Vadhan-Raj
Recombinant interleukin-2 in combination with recombinant interferon-gamma in patients with advanced malignancy: a phase 1 study.
Journal of immunotherapy (Hagerstown, Md. : 1997) 1997;20(1):79-87.
1996: M J Frederick; T K Yu; E G Krohn; D A Johnston; Elizabeth A Grimm
Protein tyrosine kinase inhibition blocks granule exocytosis and cytolytic function of lymphokine-activated killer cells.
Immunopharmacology 1996;35(2):83-102.
1996: E Roussel; M C Gingras; Elizabeth A Grimm; Janet M Bruner; R P Moser
Predominance of a type 2 intratumoural immune response in fresh tumour-infiltrating lymphocytes from human gliomas.
Clinical and experimental immunology 1996;105(2):344-52.
1996: G M Francis; E G Krohn; K V Woods; Antonio C Buzaid; Elizabeth A Grimm
Interleukin-6 production and secretion in human melanoma cell lines: regulation by interleukin-1.
Melanoma research 1996;6(3):191-201.
1996: C M Anderson; Antonio C Buzaid; Elizabeth A Grimm
Interaction of chemotherapy and biological response modifiers in the treatment of melanoma.
Cancer treatment and research 1996;87():357-80.
1996: F A Jung; Antonio C Buzaid; K V Woods; M Ross; Elizabeth A Grimm
Detection of melanoma cells in peripheral blood using reverse transcription polymerase chain reaction assay for tyrosinase mRNA.
Cancer surveys 1996;26():251-65.
1996: M J Frederick; L V Rodriguez; D A Johnston; Bryant G Darnay; Elizabeth A Grimm
Characterization of the M(r) 65,000 lymphokine-activated killer proteins phosphorylated after tumor target binding: evidence that pp65a and pp65b are phosphorylated forms of L-plastin.
Cancer research 1996;56(1):138-44.
1996: M J Frederick; L V Rodriguez; D A Johnston; Elizabeth A Grimm
Tumor target binding induces phosphorylation of two M(r) 65,000 lymphokine-activated killer proteins.
Cancer research 1996;56(1):127-37.
1995: E Roussel; M C Gingras; Elizabeth A Grimm; Jack A Roth
High expression of adhesion molecules/activation markers with little interleukin-2, interferon gamma, and tumor necrosis factor beta gene activation in fresh tumor-infiltrating lymphocytes from lung adenocarcinoma.
Cancer immunology, immunotherapy : CII 1995;41(1):1-9.
1995: D S Tyler; G M Francis; M Frederick; A H Tran; Nelson G Ordóñez; J L Smith; Omar Eton; M Ross; Elizabeth A Grimm
Interleukin-1 production in tumor cells of human melanoma surgical specimens.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 1995;15(4):331-40.
1995: K M Heaton; Elizabeth A Grimm
Differential inhibition of lymphokine-activated killing, proliferation, and cytokine secretion by humanized antibodies against the low- and intermediate-affinity interleukin-2 receptors. A novel model for activation of human peripheral blood mononuclear cells by interleukin 2.
Human immunology 1995;42(3):274-80.
1994: T Fujiwara; D W Cai; R N Georges; T Mukhopadhyay; Elizabeth A Grimm; Jack A Roth
Therapeutic effect of a retroviral wild-type p53 expression vector in an orthotopic lung cancer model.
Journal of the National Cancer Institute 1994;86(19):1458-62.
1994: Antonio C Buzaid; Elizabeth A Grimm; Francis Ali-Osman; Sigrid E Ring; Omar Eton; Nicholas E Papadopoulos; Agop Bedikian; Carl Plager; Sewa S Legha; R Benjamin
Mechanism of the anti-tumour effect of biochemotherapy in melanoma: preliminary results.
Melanoma research 1994;4(5):327-30.
1994: Gary L Clayman; M G Stewart; Randal S Weber; Adel K El-Naggar; Elizabeth A Grimm
Human papillomavirus in laryngeal and hypopharyngeal carcinomas. Relationship to survival.
Archives of otolaryngology--head & neck surgery 1994;120(7):743-8.
1994: Toshiyoshi Fujiwara; Elizabeth A Grimm; T Mukhopadhyay; W W Zhang; Laurie B Owen-Schaub; Jack A Roth
Induction of chemosensitivity in human lung cancer cells in vivo by adenovirus-mediated transfer of the wild-type p53 gene.
Cancer research 1994;54(9):2287-91.
1994: K M Heaton; G Ju; Elizabeth A Grimm
Induction of lymphokine-activated killing with reduced secretion of interleukin-1 beta, tumor necrosis factor-alpha, and interferon-gamma by interleukin-2 analogs.
Annals of surgical oncology 1994;1(3):198-203.
1994: Toshiyoshi Fujiwara; T Mukhopadhyay; D W Cai; D K Morris; Jack A Roth; Elizabeth A Grimm
Retroviral-mediated transduction of p53 gene increases TGF-beta expression in a human glioblastoma cell line.
International journal of cancer. Journal international du cancer 1994;56(6):834-9.
1993: Toshiyoshi Fujiwara; Elizabeth A Grimm; T Mukhopadhyay; D W Cai; Laurie B Owen-Schaub; Jack A Roth
A retroviral wild-type p53 expression vector penetrates human lung cancer spheroids and inhibits growth by inducing apoptosis.
Cancer research 1993;53(18):4129-33.
1993: K M Heaton; Elizabeth A Grimm
Cytokine combinations in immunotherapy for solid tumors: a review.
Cancer immunology, immunotherapy : CII 1993;37(4):213-9.
1993: K M Heaton; G Ju; Elizabeth A Grimm
Human interleukin 2 analogues that preferentially bind the intermediate-affinity interleukin 2 receptor lead to reduced secondary cytokine secretion: implications for the use of these interleukin 2 analogues in cancer immunotherapy.
Cancer research 1993;53(11):2597-602.
1993: K M Heaton; G Ju; D K Morris; K Delisio; P Bailon; Elizabeth A Grimm
Characterization of lymphokine-activated killing by human peripheral blood mononuclear cells stimulated with interleukin 2 (IL-2) analogs specific for the intermediate affinity IL-2 receptor.
Cellular immunology 1993;147(1):167-79.
1993: Toshiyoshi Fujiwara; W G Loudon; Elizabeth A Grimm
Clones derived from human natural killer cells are susceptible to lysis by human interleukin-2-activated killer cells.
Lymphokine and cytokine research 1993;12(1):45-8.
1993: J Koberda; Elizabeth A Grimm; R P Moser
Effect of anti-CD3/anti-CD28/interleukin-2 stimulation of mononuclear cells on transforming growth factor beta inhibition of lymphokine-activated killer cell generation.
Journal of cancer research and clinical oncology 1993;119(3):131-6.
1992: A W Lazenby; Jack A Roth; Laurie B Owen-Schaub; Elizabeth A Grimm
IL-1 synergy with IL-2 in the generation of lymphokine activated killer cells is mediated by TNF-alpha and beta (lymphotoxin).
Cytokine 1992;4(6):479-87.
1992: Toshiyoshi Fujiwara; Elizabeth A Grimm
Specific inhibition of interleukin 1 beta gene expression by an antisense oligonucleotide: obligatory role of interleukin 1 in the generation of lymphokine-activated killer cells.
Cancer research 1992;52(18):4954-9.
1992: S Lagoo-Deenadayalan; A S Lagoo; K J Hardy; Elizabeth A Grimm
Tumor recognition and lytic competence of IL-2-activated lymphocytes: regulation of both antibody-independent and -dependent cellular cytotoxicity via P75 IL-2 receptor.
Lymphokine and cytokine research 1992;11(4):207-13.
1992: Toshiyoshi Fujiwara; Elizabeth A Grimm
Regulation of lymphokine-activated killer cell induction by human recombinant IL-1 receptor antagonist. Obligate paracrine pathway of IL-1 during lymphokine-activated killer cell induction.
Journal of immunology (Baltimore, Md. : 1950) 1992;148(9):2941-6.
1992: J List; R P Moser; M Steuer; W G Loudon; J B Blacklock; Elizabeth A Grimm
Cytokine responses to intraventricular injection of interleukin 2 into patients with leptomeningeal carcinomatosis: rapid induction of tumor necrosis factor alpha, interleukin 1 beta, interleukin 6, gamma-interferon, and soluble interleukin 2 receptor (Mr 55,000 protein).
Cancer research 1992;52(5):1123-8.
1992: Laurie B Owen-Schaub; S Yonehara; W L Crump; Elizabeth A Grimm
DNA fragmentation and cell death is selectively triggered in activated human lymphocytes by Fas antigen engagement.
Cellular immunology 1992;140(1):197-205.
1992: Stephen C Yang; Elizabeth A Grimm; J A Roth
Combination immunotherapy for advanced lung cancer.
Journal of the National Cancer Institute. Monographs 1992;(13):197-201.
1991: Stephen C Yang; K D Fry; Elizabeth A Grimm; Jack A Roth
Phenotype and cytolytic activity of mouse tumor-bearer splenocytes and tumor-infiltrating lymphocytes from K-1735 melanoma metastases following anti-CD3, interleukin-2, and tumor necrosis factor-alpha combination immunotherapy.
Journal of immunotherapy : official journal of the Society for Biological Therapy 1991;10(5):326-35.
1991: Stephen C Yang; Elizabeth A Grimm; D R Parkinson; J Carinhas; K D Fry; A Mendiguren-Rodriguez; J Licciardello; Laurie B Owen-Schaub; Waun Ki Hong; Jack A Roth
Clinical and immunomodulatory effects of combination immunotherapy with low-dose interleukin 2 and tumor necrosis factor alpha in patients with advanced non-small cell lung cancer: a phase I trial.
Cancer research 1991;51(14):3669-76.
1991: Elizabeth A Grimm; Laurie B Owen-Schaub
The IL-2 mediated amplification of cellular cytotoxicity.
Journal of cellular biochemistry 1991;45(4):335-9.
1991: Laurie B Owen-Schaub; M de Mars; E C Murphy; Elizabeth A Grimm
IL-2 dose regulates TNF-alpha mRNA transcription and protein secretion in human peripheral blood lymphocytes.
Cellular immunology 1991;132(1):193-200.
1991: Elizabeth A Grimm; Janet M Bruner; J Carinhas; J A Köppen; W G Loudon; Laurie B Owen-Schaub; PA Steck; R P Moser
Characterization of interleukin-2-initiated versus OKT3-initiated human tumor-infiltrating lymphocytes from glioblastoma multiforme: growth characteristics, cytolytic activity, and cell phenotype.
Cancer immunology, immunotherapy : CII 1991;32(6):391-9.
1990: Stimson P Schantz; Gary L Clayman; T Racz; Elizabeth A Grimm; F J Liu; P Lavedan; D Taylor; C Pellegrino; Howard E Savage
The in vivo biologic effect of interleukin 2 and interferon alfa on natural immunity in patients with head and neck cancer.
Archives of otolaryngology--head & neck surgery 1990;116(11):1302-8.
1990: W L Crump; Laurie B Owen-Schaub; Elizabeth A Grimm
Molecular identification of the human tumor necrosis factor receptor on interleukin-2-stimulated peripheral blood lymphocytes.
Cellular immunology 1990;131(1):150-8.
1990: Stephen C Yang; Laurie B Owen-Schaub; Jack A Roth; Elizabeth A Grimm
Characterization of OKT3-initiated lymphokine-activated effectors expanded with interleukin 2 and tumor necrosis factor alpha.
Cancer research 1990;50(12):3526-32.
1990: T Irimura; A M McIsaac; D A Carlson; M Yagita; Elizabeth A Grimm; David G Menter; D M Ota; K R Clary
Soluble factor in normal tissues that stimulates high-molecular-weight sialoglycoprotein production by human colon carcinoma cells.
Cancer research 1990;50(11):3331-8.
1990: Stephen C Yang; K D Fry; Elizabeth A Grimm; Jack A Roth
Successful combination immunotherapy for the generation in vivo of antitumor activity with anti-CD3, interleukin 2, and tumor necrosis factor alpha.
Archives of surgery (Chicago, Ill. : 1960) 1990;125(2):220-5.
1990: Laurie B Owen-Schaub; M De Mars; E C Murphy; Elizabeth A Grimm
TNF-beta (lymphotoxin) strongly upregulates TNF-alpha gene expression in human peripheral blood lymphocytes.
Lymphokine research 1990;9(4):491-7.
1989: Laurie B Owen-Schaub; W L Crump; G I Morin; Elizabeth A Grimm
Regulation of lymphocyte tumor necrosis factor receptors by IL-2.
Journal of immunology (Baltimore, Md. : 1950) 1989;143(7):2236-41.
1989: W L Crump; Laurie B Owen-Schaub; Elizabeth A Grimm
Synergy of human recombinant interleukin 1 with interleukin 2 in the generation of lymphokine-activated killer cells.
Cancer research 1989;49(1):149-53.
1989: Stephen C Yang; Laurie B Owen-Schaub; Elizabeth A Grimm; Jack A Roth
Induction of lymphokine-activated killer cytotoxicity with interleukin-2 and tumor necrosis factor-alpha against primary lung cancer targets.
Cancer immunology, immunotherapy : CII 1989;29(3):193-8.
1988: R E George; W G Loudon; R P Moser; Janet M Bruner; PA Steck; Elizabeth A Grimm
In vitro cytolysis of primitive neuroectodermal tumors of the posterior fossa (medulloblastoma) by lymphokine-activated killer cells.
Journal of neurosurgery 1988;69(3):403-9.
1988: J A Wolf; Elizabeth A Grimm
Activated lymphocyte cytotoxicity: concepts and confusions.
Annales de l'Institut Pasteur. Immunology 1988;139(4):435-8.
1988: Laurie B Owen-Schaub; J U Gutterman; Elizabeth A Grimm
Synergy of tumor necrosis factor and interleukin 2 in the activation of human cytotoxic lymphocytes: effect of tumor necrosis factor alpha and interleukin 2 in the generation of human lymphokine-activated killer cell cytotoxicity.
Cancer research 1988;48(4):788-92.
1988: Elizabeth A Grimm; W L Crump; April Durett; J P Hester; S Lagoo-Deenadalayan; Laurie B Owen-Schaub
TGF-beta inhibits the in vitro induction of lymphokine-activated killing activity.
Cancer immunology, immunotherapy : CII 1988;27(1):53-8.
1988: Elizabeth A Grimm; Laurie B Owen-Schaub; W G Loudon; M Yagita
Lymphokine-activated killer cells. Induction and function.
Annals of the New York Academy of Sciences 1988;532():380-6.
1988: Laurie B Owen-Schaub; W G Loudon; M Yagita; Elizabeth A Grimm
Functional differentiation of human lymphokine-activated killing (LAK) is distinct from expansion and involves dissimilar interleukin 2 receptors.
Cellular immunology 1988;111(1):235-46.
1987: Elizabeth A Grimm
Interleukin-2 activated cytotoxic lymphocytes and their application in the intraoperative immunotherapy of local tumors.
Progress in clinical and biological research 1987;244():185-95.