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Leander Grode

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Leander Grode; Christiane Brohm; Bernd Eisele; Christian A Ganoza; January Weiner; Stefan H E Kaufmann
Safety and immunogenicity of the recombinant BCG vaccine VPM1002 in a phase 1 open-label randomized clinical trial.
Christiane Desel; Anca Dorhoi; Bernd Eisele; Leander Grode; Silke Bandermann; Stefan H E Kaufmann
Recombinant BCG ΔureC hly+ induces superior protection over parental BCG by stimulating a balanced combination of type 1 and type 17 cytokine responses.
Helmy Rachman; Michael Strong; Timo Ulrichs; Leander Grode; Johannes Schuchhardt; Hans-Joachim Mollenkopf; George A Kosmiadi; David Eisenberg; Stefan H E Kaufmann
Unique transcriptome signature of Mycobacterium tuberculosis in pulmonary tuberculosis.

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All Publications

2013: Leander Grode; Christiane Brohm; Bernd Eisele; Christian A Ganoza; January Weiner; Stefan H E Kaufmann
Safety and immunogenicity of the recombinant BCG vaccine VPM1002 in a phase 1 open-label randomized clinical trial.
Vaccine 2013;31(9):1340-8.
2011: Christiane Desel; Anca Dorhoi; Bernd Eisele; Leander Grode; Silke Bandermann; Stefan H E Kaufmann
Recombinant BCG ΔureC hly+ induces superior protection over parental BCG by stimulating a balanced combination of type 1 and type 17 cytokine responses.
The Journal of infectious diseases 2011;204(10):1573-84.
2006: Helmy Rachman; Michael Strong; Timo Ulrichs; Leander Grode; Johannes Schuchhardt; Hans-Joachim Mollenkopf; George A Kosmiadi; David Eisenberg; Stefan H E Kaufmann
Unique transcriptome signature of Mycobacterium tuberculosis in pulmonary tuberculosis.
Infection and immunity 2006;74(2):1233-42.
2005: Leander Grode; Peter Seiler; Sven Baumann; Juergen H Hess; Volker Brinkmann; Ali Nasser Eddine; Peggy Mann; Christian Goosmann; Silke Bandermann; Debbie Smith; Gregory J Bancroft; Reyrat Jean-Marc; Dick Van Soolingen; Bärbel Raupach; Stefan H E Kaufmann
Increased vaccine efficacy against tuberculosis of recombinant Mycobacterium bovis bacille Calmette-Guérin mutants that secrete listeriolysin.
The Journal of clinical investigation 2005;115(9):2472-9.
2004: T Mark Doherty; Anja W Olsen; Joachim Weischenfeldt; Kris Huygen; Sushila D'Souza; Tatiana K Kondratieva; Vladimir V Yeremeev; Alexander S Apt; Bärbel Raupach; Leander Grode; Stefan Kaufmann; Peter Andersen
Comparative analysis of different vaccine constructs expressing defined antigens from Mycobacterium tuberculosis.
The Journal of infectious diseases 2004;190(12):2146-53.
2004: Hans-Joachim Mollenkopf; Leander Grode; Jens Mattow; Maik Stein; Peggy Mann; Bettina Knapp; Jeffrey Ulmer; Stefan H E Kaufmann
Application of mycobacterial proteomics to vaccine design: improved protection by Mycobacterium bovis BCG prime-Rv3407 DNA boost vaccination against tuberculosis.
Infection and immunity 2004;72(11):6471-9.
2004: Hans-Joachim Mollenkopf; Guido Dietrich; Joachim Fensterle; Leander Grode; Klaus-Dieter Diehl; Bettina Knapp; Manmohan Singh; Derek T O'Hagan; Jeffrey B Ulmer; Stefan H E Kaufmann
Enhanced protective efficacy of a tuberculosis DNA vaccine by adsorption onto cationic PLG microparticles.
Vaccine 2004;22(21-22):2690-5.
2003: Peter Aichele; Jana Zinke; Leander Grode; Reto Schwendener; Stefan H E Kaufmann; Peter Seiler
Macrophages of the splenic marginal zone are essential for trapping of blood-borne particulate antigen but dispensable for induction of specific T cell responses.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(3):1148-55.
2002: Heidrun Koebernick; Leander Grode; John R David; Wolfgang Rohde; Michael S Rolph; Hans-Willi Mittrücker; Stefan H E Kaufmann
Macrophage migration inhibitory factor (MIF) plays a pivotal role in immunity against Salmonella typhimurium.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(21):13681-6.
2002: Leander Grode; Mischo Kursar; Joachim Fensterle; Stefan H E Kaufmann; Juergen H Hess
Cell-mediated immunity induced by recombinant Mycobacterium bovis Bacille Calmette-Guérin strains against an intracellular bacterial pathogen: importance of antigen secretion or membrane-targeted antigen display as lipoprotein for vaccine efficacy.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(4):1869-76.
2002: Hans-Joachim Mollenkopf; Jens Mattow; Ulrich E Schaible; Leander Grode; Stefan H E Kaufmann; Peter Jungblut
Mycobacterial proteomes.
Methods in enzymology 2002;358():242-56.
2001: Peter Seiler; Reto Schwendener; Silke Bandermann; Volker Brinkmann; Leander Grode; Stefan H E Kaufmann; Peter Aichele
Limited mycobacterial infection of the liver as a consequence of its microanatomical structure causing restriction of mycobacterial growth to professional phagocytes.
Infection and immunity 2001;69(12):7922-6.
2001: Leander Grode; Stefan H E Kaufmann; Juergen H Hess
Contribution of MHC class I-dependent immune mechanisms induced by attenuated recombinant Salmonella typhimurium secreting superoxide dismutase to protection against murine listeriosis.
Vaccine 2001;19(23-24):3269-72.
2001: Ivaylo Gentschev; Guido Dietrich; Simone Spreng; Annette Kolb-Mäurer; Volker Brinkmann; Leander Grode; Juergen H Hess; Stefan H E Kaufmann; Werner Goebel
Recombinant attenuated bacteria for the delivery of subunit vaccines.
Vaccine 2001;19(17-19):2621-8.
2000: Juergen H Hess; Leander Grode; Ivaylo Gentschev; Joachim Fensterle; Guido Dietrich; Werner Goebel; Stefan H E Kaufmann
Secretion of different listeriolysin cognates by recombinant attenuated Salmonella typhimurium: superior efficacy of haemolytic over non-haemolytic constructs after oral vaccination.
Microbes and infection / Institut Pasteur 2000;2(15):1799-806.
2000: Juergen H Hess; Leander Grode; J Hellwig; P Conradt; Ivaylo Gentschev; Werner Goebel; CH Ladel; Stefan H E Kaufmann
Protection against murine tuberculosis by an attenuated recombinant Salmonella typhimurium vaccine strain that secretes the 30-kDa antigen of Mycobacterium bovis BCG.
FEMS immunology and medical microbiology 2000;27(4):283-9.
1999: Joachim Fensterle; Leander Grode; Juergen H Hess; Stefan H E Kaufmann
Effective DNA vaccination against listeriosis by prime/boost inoculation with the gene gun.
Journal of immunology (Baltimore, Md. : 1950) 1999;163(8):4510-8.