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Alan Grodzinsky
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14
Sandy, John
13
Lark, Michael
13
Patwari, Parth
10
Hunziker, Ernst
10
Kurz, Bodo
10
Plaas, Anna
9
Jin, Moonsoo
8
DiMicco, Michael
8
Frank, Eliot
8
Quinn, Thomas
7
Kisiday, John
7
Ortiz, Christine
6
Hung, Han-Hwa
6
Sah, Robert
6
Trippel, Stephen
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All Publications
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2009: Sui Yihong; Lee Jennifer H; DiMicco Michael A; Vanderploeg Eric J; Blake Simon M; Hung Han-Hwa; Plaas Anna H K; James Ian E; Song Xiao-Yu; Lark Michael W; Grodzinsky Alan J
Mechanical injury potentiates proteoglycan catabolism induced by interleukin-6 with soluble interleukin-6 receptor and tumor necrosis factor alpha in immature bovine and adult human articular cartilage.
Arthritis and rheumatism 2009;60(10):2985-96.
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2009: Lee J H; Fitzgerald J B; DiMicco M A; Cheng D M; Flannery C R; Sandy J D; Plaas A H; Grodzinsky A J
Co-culture of mechanically injured cartilage with joint capsule tissue alters chondrocyte expression patterns and increases ADAMTS5 production.
Archives of biochemistry and biophysics 2009;489(1-2):118-26.
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2009: Ahn Andrew C; Grodzinsky Alan J
Relevance of collagen piezoelectricity to "Wolff's Law": a critical review.
Medical engineering & physics 2009;31(7):733-41.
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2009: Patwari P; Lin S N; Kurz B; Cole A A; Kumar S; Grodzinsky A J
Potent inhibition of cartilage biosynthesis by coincubation with joint capsule through an IL-1-independent pathway.
Scandinavian journal of medicine & science in sports 2009;19(4):528-35.
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2009: Kisiday John D; Lee Jennifer H; Siparsky Patrick N; Frisbie David D; Flannery Carl R; Sandy John D; Grodzinsky Alan J
Catabolic responses of chondrocyte-seeded peptide hydrogel to dynamic compression.
Annals of biomedical engineering 2009;37(7):1368-75.
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2009: Wheeler C A; Jafarzadeh S R; Rocke D M; Grodzinsky A J
IGF-1 does not moderate the time-dependent transcriptional patterns of key homeostatic genes induced by sustained compression of bovine cartilage.
Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society 2009;17(7):944-52.
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2009: Stevens Anna L; Wishnok John S; White Forest M; Grodzinsky Alan J; Tannenbaum Steven R
Mechanical injury and cytokines cause loss of cartilage integrity and upregulate proteins associated with catabolism, immunity, inflammation, and repair.
Molecular & cellular proteomics : MCP 2009;8(7):1475-89.
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2008: Han Lin; Dean Delphine; Daher Laura A; Grodzinsky Alan J; Ortiz Christine
Cartilage aggrecan can undergo self-adhesion.
Biophysical journal 2008;95(10):4862-70.
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2008: Pfeiffer E; Vickers S M; Frank E; Grodzinsky A J; Spector M
The effects of glycosaminoglycan content on the compressive modulus of cartilage engineered in type II collagen scaffolds.
Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society 2008;16(10):1237-44.
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2008: Lin Zhen; Fitzgerald Jonathan B; Xu Jiake; Willers Craig; Wood David; Grodzinsky Alan J; Zheng Ming H
Gene expression profiles of human chondrocytes during passaged monolayer cultivation.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2008;26(9):1230-7.
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2008: Tokunou Tomotake; Miller Rachel; Patwari Parth; Davis Michael E; Segers Vincent F M; Grodzinsky Alan J; Lee Richard T
Engineering insulin-like growth factor-1 for local delivery.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2008;22(6):1886-93.
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2008: Rolauffs Bernd; Williams James M; Grodzinsky Alan J; Kuettner Klaus E; Cole Ada A
Distinct horizontal patterns in the spatial organization of superficial zone chondrocytes of human joints.
Journal of structural biology 2008;162(2):335-44.
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2008: Stevens A L; Wheeler C A; Tannenbaum S R; Grodzinsky A J
Nitric oxide enhances aggrecan degradation by aggrecanase in response to TNF-alpha but not IL-1beta treatment at a post-transcriptional level in bovine cartilage explants.
Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society 2008;16(4):489-97.
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2008: Fitzgerald Jonathan B; Jin Moonsoo; Chai Diana H; Siparsky Patrick; Fanning Paul; Grodzinsky Alan J
Shear- and compression-induced chondrocyte transcription requires MAPK activation in cartilage explants.
The Journal of biological chemistry 2008;283(11):6735-43.
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2008: Stevens Anna L; Wishnok John S; Chai Diana H; Grodzinsky Alan J; Tannenbaum Steven R
A sodium dodecyl sulfate-polyacrylamide gel electrophoresis-liquid chromatography tandem mass spectrometry analysis of bovine cartilage tissue response to mechanical compression injury and the inflammatory cytokines tumor necrosis factor alpha and interleukin-1beta.
Arthritis and rheumatism 2008;58(2):489-500.
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2007: Dimicco M A; Kisiday J D; Gong H; Grodzinsky A J
Structure of pericellular matrix around agarose-embedded chondrocytes.
Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society 2007;15(10):1207-16.
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2007: Han Lin; Dean Delphine; Mao Pan; Ortiz Christine; Grodzinsky Alan J
Nanoscale shear deformation mechanisms of opposing cartilage aggrecan macromolecules.
Biophysical journal 2007;93(5):L23-5.
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2007: Han Lin; Dean Delphine; Ortiz Christine; Grodzinsky Alan J
Lateral nanomechanics of cartilage aggrecan macromolecules.
Biophysical journal 2007;92(4):1384-98.
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2007: Patwari Parth; Cheng Debbie M; Cole Ada A; Kuettner Klaus E; Grodzinsky Alan J
Analysis of the relationship between peak stress and proteoglycan loss following injurious compression of human post-mortem knee and ankle cartilage.
Biomechanics and modeling in mechanobiology 2007;6(1-2):83-9.
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2007: Ng Laurel; Hung Han-Hwa; Sprunt Alexander; Chubinskaya Susan; Ortiz Christine; Grodzinsky Alan
Nanomechanical properties of individual chondrocytes and their developing growth factor-stimulated pericellular matrix.
Journal of biomechanics 2007;40(5):1011-23.
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2006: Behera Aruna K; Hildebrand Ethan; Szafranski Jon; Hung Han-Hwa; Grodzinsky Alan J; Lafyatis Robert; Koch Alisa E; Kalish Robert; Perides George; Steere Allen C; Hu Linden T
Role of aggrecanase 1 in Lyme arthritis.
Arthritis and rheumatism 2006;54(10):3319-29.
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2006: Fitzgerald Jonathan B; Jin Moonsoo; Grodzinsky Alan J
Shear and compression differentially regulate clusters of functionally related temporal transcription patterns in cartilage tissue.
The Journal of biological chemistry 2006;281(34):24095-103.
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2006: Dean Delphine; Han Lin; Grodzinsky Alan J; Ortiz Christine
Compressive nanomechanics of opposing aggrecan macromolecules.
Journal of biomechanics 2006;39(14):2555-65.
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2005: Kurz Bodo; Lemke Angelika K; Fay Jakob; Pufe Thomas; Grodzinsky Alan J; Schünke Michael
Pathomechanisms of cartilage destruction by mechanical injury.
Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft 2005;187(5-6):473-85.
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2005: Bathe Mark; Rutledge Gregory C; Grodzinsky Alan J; Tidor Bruce
Osmotic pressure of aqueous chondroitin sulfate solution: a molecular modeling investigation.
Biophysical journal 2005;89(4):2357-71.
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2005: Seog Joonil; Dean Delphine; Rolauffs Bernd; Wu Tao; Genzer Jan; Plaas Anna H K; Grodzinsky Alan J; Ortiz Christine
Nanomechanics of opposing glycosaminoglycan macromolecules.
Journal of biomechanics 2005;38(9):1789-97.
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2005: Lee Jennifer H; Fitzgerald Jonathan B; Dimicco Michael A; Grodzinsky Alan J
Mechanical injury of cartilage explants causes specific time-dependent changes in chondrocyte gene expression.
Arthritis and rheumatism 2005;52(8):2386-95.
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2005: Bathe Mark; Rutledge Gregory C; Grodzinsky Alan J; Tidor Bruce
A coarse-grained molecular model for glycosaminoglycans: application to chondroitin, chondroitin sulfate, and hyaluronic acid.
Biophysical journal 2005;88(6):3870-87.
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2005: Patwari P; Gao G; Lee J H; Grodzinsky A J; Sandy J D
Analysis of ADAMTS4 and MT4-MMP indicates that both are involved in aggrecanolysis in interleukin-1-treated bovine cartilage.
Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society 2005;13(4):269-77.
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2005: Kisiday John D; Kurz Bodo; DiMicco Michael A; Grodzinsky Alan J
Evaluation of medium supplemented with insulin-transferrin-selenium for culture of primary bovine calf chondrocytes in three-dimensional hydrogel scaffolds.
Tissue engineering 2005;11(1-2):141-51.
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2004: Szafranski Jon D; Grodzinsky Alan J; Burger Elke; Gaschen Veronique; Hung Han-Hwa; Hunziker Ernst B
Chondrocyte mechanotransduction: effects of compression on deformation of intracellular organelles and relevance to cellular biosynthesis.
Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society 2004;12(12):937-46.
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2004: Bathe M; Grodzinsky A J; Tidor B; Rutledge G C
Optimal linearized Poisson-Boltzmann theory applied to the simulation of flexible polyelectrolytes in solution.
The Journal of chemical physics 2004;121(16):7557-61.
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2004: Wagner Tim A; Zahn Markus; Grodzinsky Alan J; Pascual-Leone Alvaro
Three-dimensional head model simulation of transcranial magnetic stimulation.
IEEE transactions on bio-medical engineering 2004;51(9):1586-98.
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2004: Kisiday John D; Jin Moonsoo; DiMicco Michael A; Kurz Bodo; Grodzinsky Alan J
Effects of dynamic compressive loading on chondrocyte biosynthesis in self-assembling peptide scaffolds.
Journal of biomechanics 2004;37(5):595-604.
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2004: Fitzgerald Jonathan B; Jin Moonsoo; Dean Delphine; Wood David J; Zheng Ming H; Grodzinsky Alan J
Mechanical compression of cartilage explants induces multiple time-dependent gene expression patterns and involves intracellular calcium and cyclic AMP.
The Journal of biological chemistry 2004;279(19):19502-11.
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2004: DiMicco Michael A; Patwari Parth; Siparsky Patrick N; Kumar Sanjay; Pratta Michael A; Lark Michael W; Kim Young-Jo; Grodzinsky Alan J
Mechanisms and kinetics of glycosaminoglycan release following in vitro cartilage injury.
Arthritis and rheumatism 2004;50(3):840-8.
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2004: Patwari P; Gaschen V; James I E; Berger E; Blake S M; Lark M W; Grodzinsky A J; Hunziker E B
Ultrastructural quantification of cell death after injurious compression of bovine calf articular cartilage.
Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society 2004;12(3):245-52.
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2004: Gouze J-N; Gouze E; Palmer G D; Kaneto H; Ghivizzani S C; Grodzinsky A J; Evans C H
Adenovirus-mediated gene transfer of glutamine: fructose-6-phosphate amidotransferase antagonizes the effects of interleukin-1beta on rat chondrocytes.
Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society 2004;12(3):217-24.
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2004: Kurz Bodo; Lemke Angelika; Kehn Melanie; Domm Christian; Patwari Parth; Frank Eliot H; Grodzinsky Alan J; Schünke Michael
Influence of tissue maturation and antioxidants on the apoptotic response of articular cartilage after injurious compression.
Arthritis and rheumatism 2004;50(1):123-30.
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2004: Pufe Thomas; Lemke Angelika; Kurz Bodo; Petersen Wolf; Tillmann Bernhard; Grodzinsky Alan J; Mentlein Rolf
Mechanical overload induces VEGF in cartilage discs via hypoxia-inducible factor.
The American journal of pathology 2004;164(1):185-92.
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2004: Frank E; Evans R; Lee C; Treppo S; Spector M; Grodzinsky A
Quantitative electrical impedance analysis of cartilage degradation.
Biorheology 2004;41(3-4):195-202.
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2004: Gouze Jean-Noel; Stoddart Martin J; Gouze Elvire; Palmer Glyn D; Ghivizzani Steven C; Grodzinsky Alan J; Evans Christopher H
In vitro gene transfer to chondrocytes and synovial fibroblasts by adenoviral vectors.
Methods in molecular medicine 2004;100():147-64.
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2004: Kisiday John; Kerin Alex; Grodzinsky Alan
Mechanical testing of cell-material constructs: a review.
Methods in molecular biology (Clifton, N.J.) 2004;238():239-54.
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2003: Fanning Paul J; Emkey Gregory; Smith Robert J; Grodzinsky Alan J; Szasz Nora; Trippel Stephen B
Mechanical regulation of mitogen-activated protein kinase signaling in articular cartilage.
The Journal of biological chemistry 2003;278(51):50940-8.
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2003: Ng Laurel; Grodzinsky Alan J; Patwari Parth; Sandy John; Plaas Anna; Ortiz Christine
Individual cartilage aggrecan macromolecules and their constituent glycosaminoglycans visualized via atomic force microscopy.
Journal of structural biology 2003;143(3):242-57.
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2003: Garcia A Minerva; Szasz Nora; Trippel Stephen B; Morales Teresa I; Grodzinsky Alan J; Frank Eliot H
Transport and binding of insulin-like growth factor I through articular cartilage.
Archives of biochemistry and biophysics 2003;415(1):69-79.
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2003: Jin Moonsoo; Emkey Greg R; Siparsky Patrick; Trippel Stephen B; Grodzinsky Alan J
Combined effects of dynamic tissue shear deformation and insulin-like growth factor I on chondrocyte biosynthesis in cartilage explants.
Archives of biochemistry and biophysics 2003;414(2):223-31.
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2003: Patwari Parth; Cook Michael N; DiMicco Michael A; Blake Simon M; James Ian E; Kumar Sanjay; Cole Ada A; Lark Michael W; Grodzinsky Alan J
Proteoglycan degradation after injurious compression of bovine and human articular cartilage in vitro: interaction with exogenous cytokines.
Arthritis and rheumatism 2003;48(5):1292-301.
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2003: Lee C R; Grodzinsky A J; Spector M
Biosynthetic response of passaged chondrocytes in a type II collagen scaffold to mechanical compression.
Journal of biomedical materials research. Part A 2003;64(3):560-9.
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2003: Lee C R; Grodzinsky A J; Hsu H-P; Spector M
Effects of a cultured autologous chondrocyte-seeded type II collagen scaffold on the healing of a chondral defect in a canine model.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2003;21(2):272-81.
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2003: Lee C R; Grodzinsky A J; Spector M
Modulation of the contractile and biosynthetic activity of chondrocytes seeded in collagen-glycosaminoglycan matrices.
Tissue engineering 2003;9(1):27-36.
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2003: Gouze Jean-Noel; Gouze Elvire; Palmer Glyn D; Liew Victor S; Pascher Arnulf; Betz Oliver B; Thornhill Thomas S; Evans Christopher H; Grodzinsky Alan J; Ghivizzani Steven C
A comparative study of the inhibitory effects of interleukin-1 receptor antagonist following administration as a recombinant protein or by gene transfer.
Arthritis research & therapy 2003;5(5):R301-9.
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2003: Lee Jennifer H; Kisiday John; Grodzinsky Alan J
Tissue-engineered versus native cartilage: linkage between cellular mechano-transduction and biomechanical properties.
Novartis Foundation symposium 2003;249():52-64; discussion 64-9, 170-4, 239-41.
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2002: Quinn Thomas M; Studer Claude; Grodzinsky Alan J; Meister Jean-Jacques
Preservation and analysis of nonequilibrium solute concentration distributions within mechanically compressed cartilage explants.
Journal of biochemical and biophysical methods 2002;52(2):83-95.
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2002: Kisiday J; Jin M; Kurz B; Hung H; Semino C; Zhang S; Grodzinsky A J
Self-assembling peptide hydrogel fosters chondrocyte extracellular matrix production and cell division: implications for cartilage tissue repair.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(15):9996-10001.
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2002: Kerin A; Patwari P; Kuettner K; Cole A; Grodzinsky A
Molecular basis of osteoarthritis: biomechanical aspects.
Cellular and molecular life sciences : CMLS 2002;59(1):27-35.
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2002: Quinn T M; Schmid P; Hunziker E B; Grodzinsky A J
Proteoglycan deposition around chondrocytes in agarose culture: construction of a physical and biological interface for mechanotransduction in cartilage.
Biorheology 2002;39(1-2):27-37.
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2001: Kurz B; Jin M; Patwari P; Cheng D M; Lark M W; Grodzinsky A J
Biosynthetic response and mechanical properties of articular cartilage after injurious compression.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2001;19(6):1140-6.
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2001: Jin M; Frank E H; Quinn T M; Hunziker E B; Grodzinsky A J
Tissue shear deformation stimulates proteoglycan and protein biosynthesis in bovine cartilage explants.
Archives of biochemistry and biophysics 2001;395(1):41-8.
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2001: Quinn T M; Dierickx P; Grodzinsky A J
Glycosaminoglycan network geometry may contribute to anisotropic hydraulic permeability in cartilage under compression.
Journal of biomechanics 2001;34(11):1483-90.
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2001: Patwari P; Fay J; Cook M N; Badger A M; Kerin A J; Lark M W; Grodzinsky A J
In vitro models for investigation of the effects of acute mechanical injury on cartilage.
Clinical orthopaedics and related research 2001;(391 Suppl):S61-71.
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2001: Hu L T; Eskildsen M A; Masgala C; Steere A C; Arner E C; Pratta M A; Grodzinsky A J; Loening A; Perides G
Host metalloproteinases in Lyme arthritis.
Arthritis and rheumatism 2001;44(6):1401-10.
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2001: Griffith L G; Grodzinsky A J
Advances in biomedical engineering.
JAMA : the journal of the American Medical Association 2001;285(5):556-61.
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2001: Bonassar L J; Grodzinsky A J; Frank E H; Davila S G; Bhaktav N R; Trippel S B
The effect of dynamic compression on the response of articular cartilage to insulin-like growth factor-I.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2001;19(1):11-7.
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2000: Ragan P M; Chin V I; Hung H H; Masuda K; Thonar E J; Arner E C; Grodzinsky A J; Sandy J D
Chondrocyte extracellular matrix synthesis and turnover are influenced by static compression in a new alginate disk culture system.
Archives of biochemistry and biophysics 2000;383(2):256-64.
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2000: Frank E H; Jin M; Loening A M; Levenston M E; Grodzinsky A J
A versatile shear and compression apparatus for mechanical stimulation of tissue culture explants.
Journal of biomechanics 2000;33(11):1523-7.
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2000: Lee C R; Grodzinsky A J; Hsu H P; Martin S D; Spector M
Effects of harvest and selected cartilage repair procedures on the physical and biochemical properties of articular cartilage in the canine knee.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2000;18(5):790-9.
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2000: Treppo S; Koepp H; Quan E C; Cole A A; Kuettner K E; Grodzinsky A J
Comparison of biomechanical and biochemical properties of cartilage from human knee and ankle pairs.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2000;18(5):739-48.
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2000: Loening A M; James I E; Levenston M E; Badger A M; Frank E H; Kurz B; Nuttall M E; Hung H H; Blake S M; Grodzinsky A J; Lark M W
Injurious mechanical compression of bovine articular cartilage induces chondrocyte apoptosis.
Archives of biochemistry and biophysics 2000;381(2):205-12.
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2000: Bonassar L J; Grodzinsky A J; Srinivasan A; Davila S G; Trippel S B
Mechanical and physicochemical regulation of the action of insulin-like growth factor-I on articular cartilage.
Archives of biochemistry and biophysics 2000;379(1):57-63.
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2000: Netti P A; Berk D A; Swartz M A; Grodzinsky A J; Jain R K
Role of extracellular matrix assembly in interstitial transport in solid tumors.
Cancer research 2000;60(9):2497-503.
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2000: Bhakta N R; Garcia A M; Frank E H; Grodzinsky A J; Morales T I
The insulin-like growth factors (IGFs) I and II bind to articular cartilage via the IGF-binding proteins.
The Journal of biological chemistry 2000;275(8):5860-6.
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2000: Patwari P; Kurz B; Sandy J D; Grodzinsky A J
Mannosamine inhibits aggrecanase-mediated changes in the physical properties and biochemical composition of articular cartilage.
Archives of biochemistry and biophysics 2000;374(1):79-85.
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2000: Grodzinsky A J; Levenston M E; Jin M; Frank E H
Cartilage tissue remodeling in response to mechanical forces.
Annual review of biomedical engineering 2000;2():691-713.
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2000: Martin I; Obradovic B; Treppo S; Grodzinsky A J; Langer R; Freed L E; Vunjak-Novakovic G
Modulation of the mechanical properties of tissue engineered cartilage.
Biorheology 2000;37(1-2):141-7.
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1999: Swartz M A; Kaipainen A; Netti P A; Brekken C; Boucher Y; Grodzinsky A J; Jain R K
Mechanics of interstitial-lymphatic fluid transport: theoretical foundation and experimental validation.
Journal of biomechanics 1999;32(12):1297-307.
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1999: Ragan P M; Badger A M; Cook M; Chin V I; Gowen M; Grodzinsky A J; Lark M W
Down-regulation of chondrocyte aggrecan and type-II collagen gene expression correlates with increases in static compression magnitude and duration.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 1999;17(6):836-42.
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1999: Quinn T M; Maung A A; Grodzinsky A J; Hunziker E B; Sandy J D
Physical and biological regulation of proteoglycan turnover around chondrocytes in cartilage explants. Implications for tissue degradation and repair.
Annals of the New York Academy of Sciences 1999;878():420-41.
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1999: Vunjak-Novakovic G; Martin I; Obradovic B; Treppo S; Grodzinsky A J; Langer R; Freed L E
Bioreactor cultivation conditions modulate the composition and mechanical properties of tissue-engineered cartilage.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 1999;17(1):130-8.
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1998: Garcia A M; Lark M W; Trippel S B; Grodzinsky A J
Transport of tissue inhibitor of metalloproteinases-1 through cartilage: contributions of fluid flow and electrical migration.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 1998;16(6):734-42.
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1998: Quinn T M; Grodzinsky A J; Hunziker E B; Sandy J D
Effects of injurious compression on matrix turnover around individual cells in calf articular cartilage explants.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 1998;16(4):490-9.
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1998: Quinn T M; Grodzinsky A J; Buschmann M D; Kim Y J; Hunziker E B
Mechanical compression alters proteoglycan deposition and matrix deformation around individual cells in cartilage explants.
Journal of cell science 1998;111 ( Pt 5)():573-83.
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1997: Bonassar L J; Sandy J D; Lark M W; Plaas A H; Frank E H; Grodzinsky A J
Inhibition of cartilage degradation and changes in physical properties induced by IL-1beta and retinoic acid using matrix metalloproteinase inhibitors.
Archives of biochemistry and biophysics 1997;344(2):404-12.
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1996: Bonassar L J; Stinn J L; Paguio C G; Frank E H; Moore V L; Lark M W; Sandy J D; Hollander A P; Poole A R; Grodzinsky A J
Activation and inhibition of endogenous matrix metalloproteinases in articular cartilage: effects on composition and biophysical properties.
Archives of biochemistry and biophysics 1996;333(2):359-67.
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1996: Garcia A M; Frank E H; Grimshaw P E; Grodzinsky A J
Contributions of fluid convection and electrical migration to transport in cartilage: relevance to loading.
Archives of biochemistry and biophysics 1996;333(2):317-25.
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1996: Kim Y J; Grodzinsky A J; Plaas A H
Compression of cartilage results in differential effects on biosynthetic pathways for aggrecan, link protein, and hyaluronan.
Archives of biochemistry and biophysics 1996;328(2):331-40.
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1996: Buschmann M D; Hunziker E B; Kim Y J; Grodzinsky A J
Altered aggrecan synthesis correlates with cell and nucleus structure in statically compressed cartilage.
Journal of cell science 1996;109 ( Pt 2)():499-508.
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1996: Sah R L; Trippel S B; Grodzinsky A J
Differential effects of serum, insulin-like growth factor-I, and fibroblast growth factor-2 on the maintenance of cartilage physical properties during long-term culture.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 1996;14(1):44-52.
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1996: Cheng G C; Libby P; Grodzinsky A J; Lee R T
Induction of DNA synthesis by a single transient mechanical stimulus of human vascular smooth muscle cells. Role of fibroblast growth factor-2.
Circulation 1996;93(1):99-105.
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1996: Lee E; Vaughan D E; Parikh S H; Grodzinsky A J; Libby P; Lark M W; Lee R T
Regulation of matrix metalloproteinases and plasminogen activator inhibitor-1 synthesis by plasminogen in cultured human vascular smooth muscle cells.
Circulation research 1996;78(1):44-9.
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1995: Lee E; Grodzinsky A J; Libby P; Clinton S K; Lark M W; Lee R T
Human vascular smooth muscle cell-monocyte interactions and metalloproteinase secretion in culture.
Arteriosclerosis, thrombosis, and vascular biology 1995;15(12):2284-9.
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1995: Bonassar L J; Jeffries K A; Paguio C G; Grodzinsky A J
Cartilage degradation and associated changes in biochemical and electromechanical properties.
Acta orthopaedica Scandinavica. Supplementum 1995;266():38-44.
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1995: Kim Y J; Bonassar L J; Grodzinsky A J
The role of cartilage streaming potential, fluid flow and pressure in the stimulation of chondrocyte biosynthesis during dynamic compression.
Journal of biomechanics 1995;28(9):1055-66.
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1995: Mallein-Gerin F; Ruggiero F; Quinn T M; Bard F; Grodzinsky A J; Olsen B R; van der Rest M
Analysis of collagen synthesis and assembly in culture by immortalized mouse chondrocytes in the presence or absence of alpha 1(IX) collagen chains.
Experimental cell research 1995;219(1):257-65.
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1995: Buschmann M D; Grodzinsky A J
A molecular model of proteoglycan-associated electrostatic forces in cartilage mechanics.
Journal of biomechanical engineering 1995;117(2):179-92.
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1995: Buschmann M D; Gluzband Y A; Grodzinsky A J; Hunziker E B
Mechanical compression modulates matrix biosynthesis in chondrocyte/agarose culture.
Journal of cell science 1995;108 ( Pt 4)():1497-508.
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1995: Bonassar L J; Frank E H; Murray J C; Paguio C G; Moore V L; Lark M W; Sandy J D; Wu J J; Eyre D R; Grodzinsky A J
Changes in cartilage composition and physical properties due to stromelysin degradation.
Arthritis and rheumatism 1995;38(2):173-83.
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1994: Berkenblit S I; Frank E H; Salant E P; Grodzinsky A J
Nondestructive detection of cartilage degeneration using electromechanical surface spectroscopy.
Journal of biomechanical engineering 1994;116(4):384-92.
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1994: Bonassar L J; Paguio C G; Frank E H; Jeffries K A; Moore V L; Lark M W; Caldwell C G; Hagmann W K; Grodzinsky A J
Effects of matrix metalloproteinases on cartilage biophysical properties in vitro and in vivo.
Annals of the New York Academy of Sciences 1994;732():439-43.
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1994: Kim Y J; Sah R L; Grodzinsky A J; Plaas A H; Sandy J D
Mechanical regulation of cartilage biosynthetic behavior: physical stimuli.
Archives of biochemistry and biophysics 1994;311(1):1-12.
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1994: MacGinitie L A; Gluzband Y A; Grodzinsky A J
Electric field stimulation can increase protein synthesis in articular cartilage explants.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 1994;12(2):151-60.
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1994: Loree H M; Grodzinsky A J; Park S Y; Gibson L J; Lee R T
Static circumferential tangential modulus of human atherosclerotic tissue.
Journal of biomechanics 1994;27(2):195-204.
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1994: Sah R L; Chen A C; Grodzinsky A J; Trippel S B
Differential effects of bFGF and IGF-I on matrix metabolism in calf and adult bovine cartilage explants.
Archives of biochemistry and biophysics 1994;308(1):137-47.
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1992: Buschmann M D; Gluzband Y A; Grodzinsky A J; Kimura J H; Hunziker E B
Chondrocytes in agarose culture synthesize a mechanically functional extracellular matrix.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 1992;10(6):745-58.
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1992: Lee R T; Richardson S G; Loree H M; Grodzinsky A J; Gharib S A; Schoen F J; Pandian N
Prediction of mechanical properties of human atherosclerotic tissue by high-frequency intravascular ultrasound imaging. An in vitro study.
Arteriosclerosis and thrombosis : a journal of vascular biology / American Heart Association 1992;12(1):1-5.
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1991: Lee R T; Grodzinsky A J; Frank E H; Kamm R D; Schoen F J
Structure-dependent dynamic mechanical behavior of fibrous caps from human atherosclerotic plaques.
Circulation 1991;83(5):1764-70.
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1991: Sah R L; Doong J Y; Grodzinsky A J; Plaas A H; Sandy J D
Effects of compression on the loss of newly synthesized proteoglycans and proteins from cartilage explants.
Archives of biochemistry and biophysics 1991;286(1):20-9.
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1990: Sah R L; Grodzinsky A J; Plaas A H; Sandy J D
Effects of tissue compression on the hyaluronate-binding properties of newly synthesized proteoglycans in cartilage explants.
The Biochemical journal 1990;267(3):803-8.
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1989: Gray M L; Pizzanelli A M; Lee R C; Grodzinsky A J; Swann D A
Kinetics of the chondrocyte biosynthetic response to compressive load and release.
Biochimica et biophysica acta 1989;991(3):415-25.
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1989: Sah R L; Kim Y J; Doong J Y; Grodzinsky A J; Plaas A H; Sandy J D
Biosynthetic response of cartilage explants to dynamic compression.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 1989;7(5):619-36.
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1988: Gray M L; Pizzanelli A M; Grodzinsky A J; Lee R C
Mechanical and physiochemical determinants of the chondrocyte biosynthetic response.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 1988;6(6):777-92.
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1987: Frank E H; Grodzinsky A J; Koob T J; Eyre D R
Streaming potentials: a sensitive index of enzymatic degradation in articular cartilage.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 1987;5(4):497-508.
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1987: Frank E H; Grodzinsky A J
Cartilage electromechanics--II. A continuum model of cartilage electrokinetics and correlation with experiments.
Journal of biomechanics 1987;20(6):629-39.
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1987: Frank E H; Grodzinsky A J
Cartilage electromechanics--I. Electrokinetic transduction and the effects of electrolyte pH and ionic strength.
Journal of biomechanics 1987;20(6):615-27.
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1983: Hoch D H; Grodzinsky A J; Koob T J; Albert M L; Eyre D R
Early changes in material properties of rabbit articular cartilage after meniscectomy.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 1983;1(1):4-12.
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1981: Lee R C; Frank E H; Grodzinsky A J; Roylance D K
Oscillatory compressional behavior of articular cartilage and its associated electromechanical properties.
Journal of biomechanical engineering 1981;103(4):280-92.
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