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Hiroyuki Aburatani

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Takeo Nakaya; Hiroyuki Aburatani; Rumi Hino; Shumpei Ishikawa; Yoshinao Kikuchi; Akiko Kunita; Keisuke Matsusaka; Masashi Fukayama
Enrichment of stem-like cell population comprises transformation ability of Epstein-Barr virus latent membrane protein 2A for non-transformed cells.
Bo-Kyung Son; Hiroyuki Aburatani; Masahiro Akishita; Tomio Arai; Masato Eto; Katsuya Iijima; Hidemi Ishii; Koji Maemura; Sumito Ogawa; Yasuyoshi Ouchi
Thrombomodulin, a novel molecule regulating inorganic phosphate-induced vascular smooth muscle cell calcification.
Ayumi Usui; Michael Wegner; Hiroyuki Aburatani; Atsumi Iida; Emako Miyauchi; Yujin Mochizuki; Akira Murakami; Hiromitsu Nakauchi; Shinya Satoh; Elisabeth Sock; Sumiko Watanabe
The early retinal progenitor-expressed gene Sox11 regulates the timing of the differentiation of retinal cells.

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2013: Takeo Nakaya; Hiroyuki Aburatani; Rumi Hino; Shumpei Ishikawa; Yoshinao Kikuchi; Akiko Kunita; Keisuke Matsusaka; Masashi Fukayama
Enrichment of stem-like cell population comprises transformation ability of Epstein-Barr virus latent membrane protein 2A for non-transformed cells.
Virus research 2013;174(1-2):108-15.
2013: Bo-Kyung Son; Hiroyuki Aburatani; Masahiro Akishita; Tomio Arai; Masato Eto; Katsuya Iijima; Hidemi Ishii; Koji Maemura; Sumito Ogawa; Yasuyoshi Ouchi
Thrombomodulin, a novel molecule regulating inorganic phosphate-induced vascular smooth muscle cell calcification.
Journal of molecular and cellular cardiology 2013;56():72-80.
2013: Ayumi Usui; Michael Wegner; Hiroyuki Aburatani; Atsumi Iida; Emako Miyauchi; Yujin Mochizuki; Akira Murakami; Hiromitsu Nakauchi; Shinya Satoh; Elisabeth Sock; Sumiko Watanabe
The early retinal progenitor-expressed gene Sox11 regulates the timing of the differentiation of retinal cells.
Development (Cambridge, England) 2013;140(4):740-50.
2013: Daisuke Matsubara; Yoshinori Murakami; Hiroyuki Aburatani; Shunsuke Endo; Masashi Fukayama; Hiroko Hoshino; Shumpei Ishikawa; Yuka Kishaba; Sachiko Oguni; Takashi Sakatani; Yukihiko Sugiyama; Tomoko Tamura; Toshiro Niki
Lung cancer with loss of BRG1/BRM, shows epithelial mesenchymal transition phenotype and distinct histologic and genetic features.
Cancer science 2013;104(2):266-73.
2013: Sachie Hiratsuka; Sachie Ishibashi; Hiroshi Kijima; Kensuke Miyake; Masato Murakami; Takeshi Tomita; Akira Watanabe; Hiroyuki Aburatani; Sachiko Akashi-Takamura; Yoshiro Maru
Primary tumours modulate innate immune signalling to create pre-metastatic vascular hyperpermeability foci.
Nature communications 2013;4():1853.
2013: Osamu Takase; Tsuyoshi Takato; Masahiro Yoshikawa; Hiroyuki Aburatani; Toshiro Fujita; Junichi Hirahashi; Mana Idei; Takayuki Isagawa; Genta Nagae; Hirofumi Suemori; Keiichi Hishikawa
The role of NF-κB signaling in the maintenance of pluripotency of human induced pluripotent stem cells.
PloS one 2013;8(2):e56399.
2012: Yumiko Fujii; Hiroyuki Aburatani; Shin Maeda; Hiroyuki Mutoh; Yasuyuki Seto; Hidekazu Suzuki; Shuichi Tsutsumi; Yukinori Yamagata; Kyoko Yoshihashi; Masanori Hatakeyama
CDX1 confers intestinal phenotype on gastric epithelial cells via induction of stemness-associated reprogramming factors SALL4 and KLF5.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(50):20584-9.
2012: Daisuke Matsubara; Yoshinori Murakami; Hiroyuki Aburatani; Shunsuke Endo; Masashi Fukayama; Shumpei Ishikawa; Yoshihiko Kanai; Hiroaki Kataoka; Sachiko Oguni; Shiori Ohara; Takashi Sakatani; Tomoko Tamura; Taichiro Yoshimoto; Toshiro Niki
Identification of CCDC6-RET fusion in the human lung adenocarcinoma cell line, LC-2/ad.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 2012;7(12):1872-6.
2012: Nobuhiro Shojima; N Takahashi; Iseki Takamoto; Keisuke Ueki; Toshimasa Yamauchi; Hiroyuki Aburatani; H Fujita; K Hara; M Horikoshi; Naoto Kubota; M Noda; Miho Ohsugi; Takashi Kadowaki
Depletion of homeodomain-interacting protein kinase 3 impairs insulin secretion and glucose tolerance in mice.
Diabetologia 2012;55(12):3318-30.
2012: Argyris Papantonis; Huay-Mei Poh; Xiaoan Ruan; Yijun Ruan; Patrick Short; Stephen Taylor; Shuichi Tsutsumi; Youichiro Wada; Binwei Deng; Yasuharu Kanki; Mika Kobayashi; Tatsuhiko Kodama; Takahide Kohro; Joshua D Larkin; Guoliang Li; Hiroyuki Aburatani; Sabyasachi Baboo; Peter R Cook
TNFα signals through specialized factories where responsive coding and miRNA genes are transcribed.
The EMBO journal 2012;31(23):4404-14.
2012: Hiroyuki Aburatani
[Epigenomics and epigenetic therapy of cancer].
Nihon rinsho. Japanese journal of clinical medicine 2012;70 Suppl 8():287-93.
2012: Yuki Kagiyama; Kimihito C Kawabata; Hiroyuki Aburatani; Daichi Inoue; Kumi Izawa; Jiro Kitaura; Yukiko Komeno; Toshihiro Matsukawa; Fumio Nakahara; Toshihiko Oki; Katsuaki Sato; Katsuhiro Togami; Tomoyuki Uchida; Toshio Kitamura
Upregulation of CD200R1 in lineage-negative leukemic cells is characteristic of AML1-ETO-positive leukemia in mice.
International journal of hematology 2012;96(5):638-48.
2012: Brij K Gupta; Meena Jaggi; Michael D Koch; Douglas W Lynch; Diane M Maher; Susan E Puumala; Vasudha Sundram; Akira Watanabe; Hiroyuki Aburatani; Teresa Bohlmeyer; Mara C Ebeling; Subhash C Chauhan
Increased expression and aberrant localization of mucin 13 in metastatic colon cancer.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2012;60(11):822-31.
2012: Siok-Lay Tan; Hiroyuki Aburatani; Asuka Kamio-Miura; Toshiyuki Matsui; Miyuki Nishi; Toshiyuki Ohtsuka; Yoichi Shinkai; Keiko Takemoto; Ryoichiro Kageyama
Essential roles of the histone methyltransferase ESET in the epigenetic control of neural progenitor cells during development.
Development (Cambridge, England) 2012;139(20):3806-16.
2012: Kentaro Yuda; Hiroyuki Aburatani; Tatsuya Inoue; Aya Iriyama; Kazuaki Kadonosono; Ryozo Nagai; Hidenori Takahashi; Yasuhiro Tamaki; Takashi Ueta; Yasuo Yanagi
Adrenomedullin inhibits choroidal neovascularization via CCL2 in the retinal pigment epithelium.
The American journal of pathology 2012;181(4):1464-72.
2012: Satoru Matsuda; Yumi Matsuzaki; Hiroyuki Aburatani; Akinori Akaike; Ken-ichiro Kuwako; Hirotaka James Okano; Yumiko Saga; Hachiro Sugimoto; Shuichi Tsutsumi; Hideyuki Okano
Sox21 promotes hippocampal adult neurogenesis via the transcriptional repression of the Hes5 gene.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2012;32(36):12543-57.
2012: Imari Mimura; Masaomi Nangaku; Juro Sakai; Teppei Shimamura; Jun-ichi Suehiro; Akashi Taguchi; Toshiya Tanaka; Kyoko Tanimura; Shuichi Tsutsumi; Hiroyuki Aburatani; Takanori Fujita; Takao Hamakubo; Takeshi Inagaki; Tsuyoshi Inoue; Yasuharu Kanki; Mika Kobayashi; Tatsuhiko Kodama; Takahide Kohro; Shogo Yamamoto; Youichiro Wada
Dynamic change of chromatin conformation in response to hypoxia enhances the expression of GLUT3 (SLC2A3) by cooperative interaction of hypoxia-inducible factor 1 and KDM3A.
Molecular and cellular biology 2012;32(15):3018-32.
2012: Atsushi Kaneda; Keisuke Matsusaka; Hiroyuki Aburatani; Masashi Fukayama
Epstein-Barr virus infection as an epigenetic driver of tumorigenesis.
Cancer research 2012;72(14):3445-50.
2012: Yoichiro Mitsuishi; Hiroyuki Aburatani; Yukie Kawatani; Toshihiro Nukiwa; Tatsuhiro Shibata; Keiko Taguchi; Masayuki Yamamoto; Hozumi Motohashi
Nrf2 redirects glucose and glutamine into anabolic pathways in metabolic reprogramming.
Cancer cell 2012;22(1):66-79.
2012: Keiki Kumano; Hiroyuki Aburatani; Shunya Arai; Koji Eto; Masataka Hosoi; Yasuhiko Kamikubo; Genta Nagae; Hiromitsu Nakauchi; Kumi Nakazaki; Makoto Otsu; Naoya Takayama; Kazuki Taoka; Koki Ueda; Mineo Kurokawa
Generation of induced pluripotent stem cells from primary chronic myelogenous leukemia patient samples.
Blood 2012;119(26):6234-42.
2012: Takuma Hayashi; Nobuyoshi Hiraoka; Akiko Horiuchi; Tomoyuki Ichimura; Osamu Ishiko; Yae Kanai; Mari Kasai; Ryuichiro Nishimura; Kenji Sano; Tanri Shiozawa; Tamotsu Sudo; Nobuo Yaegashi; Hiroyuki Aburatani; Ikuo Konishi
Potential role of LMP2 as an anti-oncogenic factor in human uterine leiomyosarcoma: morphological significance of calponin h1.
FEBS letters 2012;586(13):1824-31.
2012: Yuji Ikeda; Shumpei Ishikawa; Kei Kawana; Shiro Kozuma; Daichi Maeda; Satsuki Murayama-Hosokawa; Shunsuke Nakagawa; Katsutoshi Oda; Yutaka Takazawa; Osamu Wada-Hiraike; Linghua Wang; Shogo Yamamoto; Tetsu Yano; Hiroyuki Aburatani; Masashi Fukayama; Yuji Taketani
Genome-wide single nucleotide polymorphism arrays as a diagnostic tool in patients with synchronous endometrial and ovarian cancer.
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 2012;22(5):725-31.
2012: Shinichiro Niizuma; Junji Okuda; Yodo Tamaki; Shingo Tsuji; Kayo Watanabe-Maeda; Yuki Yoshida; Hiroyuki Aburatani; Yasutaka Inuzuka; Yoshitaka Iwanaga; Tohru Izumi; Takao Kato; Tsuneaki Kawashima; Takeshi Kimura; Toru Kita; Rie Kosugi; Yoji Machida; Tetsuo Shioi
Effect of persistent activation of phosphoinositide 3-kinase on heart.
Life sciences 2012;90(15-16):619-28.
2012: Ai Fukui; Hiroki Hamatani; Mizuho Homma; Mikiko Inaki; Takako Morimoto; Hiroyuki Aburatani; Gaku Tonoe; Akinao Nose
Lola regulates glutamate receptor expression at the Drosophila neuromuscular junction.
Biology open 2012;1(4):362-75.
2012: Yotaro Kudo; Genta Nagae; Keisuke Tateishi; Keisuke Yamamoto; Shinzo Yamamoto; Haruhiko Yoshida; Hiroyuki Aburatani; Yoshinari Asaoka; Hideaki Ijichi; Kazuhiko Koike
Loss of 5-hydroxymethylcytosine is accompanied with malignant cellular transformation.
Cancer science 2012;103(4):670-6.
2012: Linghua Wang; Shogo Yamamoto; Hiroki Yamaue; Seiko Hirono; Takayuki Isagawa; Minoru Isomura; Yae Kanai; Atsushi Kaneda; Tokuichi Kawaguchi; Yoshio Miki; Satsuki Murayama-Hosokawa; Genta Nagae; Koichi Nagasaki; Tetsuo Noda; Akio Saiura; Hiromi Sakamoto; Fei Sang; Tatsuhiro Shibata; Kohtaro Sonoda; Minoru Sugawara; Kenji Tatsuno; Y Totoki; Shuichi Tsutsumi; Hiroki Ueda; Hiroyuki Aburatani
Whole-exome sequencing of human pancreatic cancers and characterization of genomic instability caused by MLH1 haploinsufficiency and complete deficiency.
Genome research 2012;22(2):208-19.
2012: Koichi Yagi; Hiroyuki Aburatani; Kiwamu Akagi; Keisuke Matsusaka; Atsushi Nakajima; Yasuyuki Seto; Hirokazu Takahashi; Atsushi Kaneda
Intermediate methylation epigenotype and its correlation to KRAS mutation in conventional colorectal adenoma.
The American journal of pathology 2012;180(2):616-25.
2012: Shingo Tsuji; Sigeo Ihara; Hiroyuki Aburatani
A simple knowledge-based mining method for exploring hidden key molecules in a human biomolecular network.
BMC systems biology 2012;6():124.
2012: Toshifumi Yae; Go J Yoshida; Momoko Yoshikawa; Hiroyuki Aburatani; Takatsugu Ishimoto; Yasuharu Kanki; Akiko Kubo; Takashi Masuko; Takashi Minami; Kaoru Mogushi; Takeshi Motohara; Mitsuyo Ohmura; Tsuyoshi Osawa; Hideyuki Saya; Makoto Suematsu; Kazuhisa Takahashi; Hiroshi Tanaka; Kenji Tsuchihashi; Takeyuki Wada; Osamu Nagano
Alternative splicing of CD44 mRNA by ESRP1 enhances lung colonization of metastatic cancer cell.
Nature communications 2012;3():883.
2012: Keiko Shoji; Kenbun Sone; Michihiro Tanikawa; Osamu Wada-Hiraike; Tetsu Yano; Hiroyuki Aburatani; Haruko Hiraike; Yuji Ikeda; Tomoko Kashiyama; Kei Kawana; Takahiro Koso; Shiro Kozuma; Hiroyuki Kuramoto; Yoko Matsumoto; Frank McCormick; Yuichiro Miyamoto; Aki Miyasaka; Shunsuke Nakagawa; Katsutoshi Oda; Yuji Taketani
Genotype-dependent efficacy of a dual PI3K/mTOR inhibitor, NVP-BEZ235, and an mTOR inhibitor, RAD001, in endometrial carcinomas.
PloS one 2012;7(5):e37431.
2012: Yutaka Midorikawa; Tadatoshi Takayama; Shingo Tsuji; Hiroyuki Aburatani
Genomic approach towards personalized anticancer drug therapy.
Pharmacogenomics 2012;13(2):191-9.
2011: Keisuke Matsusaka; Genta Nagae; Yasuyuki Seto; Kenzo Takada; Hiroshi Uozaki; Tetsuo Ushiku; Hiroyuki Aburatani; Rumi Hino; Atsushi Kaneda; Yasuko Kikuchi; Masashi Fukayama
Classification of Epstein-Barr virus-positive gastric cancers by definition of DNA methylation epigenotypes.
Cancer research 2011;71(23):7187-97.
2011: Atsushi Kaneda; Kohei Miyazono; Masato Morikawa; Genta Nagae; Masanobu Oshima; Shingo Tsuji; Shogo Yamamoto; Motonobu Anai; Takanori Fujita; Hiroyuki Aburatani
Activation of Bmp2-Smad1 signal and its regulation by coordinated alteration of H3K27 trimethylation in Ras-induced senescence.
PLoS genetics 2011;7(11):e1002359.
2011: Masato Morikawa; Shuichi Tsutsumi; Eleftheria Vasilaki; Hiroyuki Aburatani; Carl-Henrik Heldin; Yasuharu Kanki; Daizo Koinuma; Kohei Miyazono
ChIP-seq reveals cell type-specific binding patterns of BMP-specific Smads and a novel binding motif.
Nucleic acids research 2011;39(20):8712-27.
2011: Tetsuro Yasui; Shuichi Tsutsumi; Hiroyuki Aburatani; Jun Hirose; Kozo Nakamura; Sakae Tanaka
Epigenetic regulation of osteoclast differentiation: possible involvement of Jmjd3 in the histone demethylation of Nfatc1.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2011;26(11):2665-71.
2011: Hironori Waki; Toshimasa Yamauchi; Jing Yu; Hiroyuki Aburatani; Tomohisa Aoyama; Takanori Fujita; Lisa Hirose-Yotsuya; Masato Iwabu; Tatsuhiko Kodama; Masahiro Nakamura; Miki Okada-Iwabu; Juro Sakai; Wei Sun; Kazumi Take; Shuichi Tsutsumi; Kohjiro Ueki; Ken-ichi Wakabayashi; Takashi Kadowaki
Global mapping of cell type-specific open chromatin by FAIRE-seq reveals the regulatory role of the NFI family in adipocyte differentiation.
PLoS genetics 2011;7(10):e1002311.
2011: Takuma Hayashi; Nobuyoshi Hiraoka; Akiko Horiuchi; Tomoyuki Ichimura; Osamu Ishiko; Yae Kanai; Mari Kasai; Satoru Nagase; Kenji Sano; Tanri Shiozawa; Susumu Tonegawa; Nobuo Yaegashi; Hiroyuki Aburatani; Ikuo Konishi
Involvement of proteasome β1i subunit, LMP2, on development of uterin leiomyosarcma.
North American journal of medical sciences 2011;3(9):394-9.
2011: Honoka Isshiki; Makoto Kano; Kazuki Sato; Hitoshi Abe; Hiroyuki Aburatani; Keisuke Horiuchi; Hiroyasu Ikegami; Shuichi Tsutsumi; Akihiro Umezawa; Yoshiaki Toyama
Gene expression profiling of mouse growth plate cartilage by laser microdissection and microarray analysis.
Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association 2011;16(5):670-2.
2011: Anna Mizutani; Masato Morikawa; Hiroshi I Suzuki; Shuichi Tsutsumi; Takeshi Imamura; Naoko Kamimura; Daizo Koinuma; Kohei Miyazono; Hiroyuki Aburatani
Cell type-specific target selection by combinatorial binding of Smad2/3 proteins and hepatocyte nuclear factor 4alpha in HepG2 cells.
The Journal of biological chemistry 2011;286(34):29848-60.
2011: Kazuhiko Nakabayashi; Tsutomu Ogata; Aurora Sanchez; Hidenobu Soejima; Chiharu Tayama; Alex Martin Trujillo; Wataru Yoshida; Hiroyuki Aburatani; Cristina Camprubi; Kenichiro Hata; Pablo Lapunzina; Genta Nagae; David Monk
Methylation screening of reciprocal genome-wide UPDs identifies novel human-specific imprinted genes.
Human molecular genetics 2011;20(16):3188-97.
2011: Daisuke Yamasaki; Natsuko Kawabe; Hitomi Nakamura; Keisuke Tachibana; Kenji Ishimoto; Toshiya Tanaka; Hiroyuki Aburatani; Juro Sakai; Takao Hamakubo; Tatsuhiko Kodama; Takefumi Doi
Fenofibrate suppresses growth of the human hepatocellular carcinoma cell via PPARα-independent mechanisms.
European journal of cell biology 2011;90(8):657-64.
2011: Akira Watanabe; Yasuhiro Yamada; Shogo Ehata; Masashi Fukayama; Yasushi Ino; Shumpei Ishikawa; Daichi Maeda; Kohei Miyazono; Akitake Mukasa; Hideki Ogiwara; Nobuhito Saito; Tomoki Todo; Keisuke Ueki; Hiroyuki Aburatani
Homozygously deleted gene DACH1 regulates tumor-initiating activity of glioma cells.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(30):12384-9.
2011: Genta Nagae; Norio Nakatsuji; Aya Nonaka; Nobuaki Shiraki; Hidenobu Soejima; Hirofumi Suemori; Shuichi Tsutsumi; Shogo Yamamoto; Sayaka Yoshiba; Takanori Fujita; Masashi Fukayama; Takayuki Isagawa; Shumpei Ishikawa; Shoen Kume; Keisuke Matsusaka; Yutaka Midorikawa; Hiroyuki Aburatani
Tissue-specific demethylation in CpG-poor promoters during cellular differentiation.
Human molecular genetics 2011;20(14):2710-21.
2011: Yasuharu Kanki; Tatsuhiko Kodama; Takahide Kohro; Imari Mimura; Hiroyuki Aburatani; Takao Hamakubo; Sigeo Ihara; Hiroko Iwanari; Shuying Jiang; Makoto Naito; Yoshihiro Ohta; Jun-Ichi Suehiro; Shuichi Tsutsumi; Youichiro Wada; Takashi Minami
Epigenetically coordinated GATA2 binding is necessary for endothelium-specific endomucin expression.
The EMBO journal 2011;30(13):2582-95.
2011: Naoto Tsuchiya; Hiroyuki Aburatani; Elise D Bowman; Yuko Fujiwara; Curtis C Harris; Masashi Izumiya; Yutaka Midorikawa; Makiko Nakai; Hiroko Ogata-Kawata; Atsushi Okabe; Koji Okamoto; Aaron J Schetter; Yasuyuki Sugiyama; Hitoshi Nakagama
Tumor suppressor miR-22 determines p53-dependent cellular fate through post-transcriptional regulation of p21.
Cancer research 2011;71(13):4628-39.
2011: Hideto Tozawa; Yasuharu Kanki; Jun-ichi Suehiro; Shuichi Tsutsumi; Takahide Kohro; Youichiro Wada; Hiroyuki Aburatani; William C Aird; Tatsuhiko Kodama; Takashi Minami
Genome-wide approaches reveal functional interleukin-4-inducible STAT6 binding to the vascular cell adhesion molecule 1 promoter.
Molecular and cellular biology 2011;31(11):2196-209.
2011: Masahiko Fujiwara; Takeshi Kashima; Akiko Kunita; Isao Kii; Daisuke Komura; Agamemnon E Grigoriadis; Akira Kudo; Hiroyuki Aburatani; Masashi Fukayama
Stable knockdown of S100A4 suppresses cell migration and metastasis of osteosarcoma.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2011;32(3):611-22.
2011: Yasushi Totoki; Kenji Tatsuno; Shogo Yamamoto; Yasuhito Arai; Fumie Hosoda; Shumpei Ishikawa; Shuichi Tsutsumi; Kohtaro Sonoda; Hirohiko Totsuka; Takuya Shirakihara; Hiromi Sakamoto; Linghua Wang; Hidenori Ojima; Kazuaki Shimada; Tomoo Kosuge; Takuji Okusaka; Kazuto Kato; Jun Kusuda; Teruhiko Yoshida; Hiroyuki Aburatani; Tatsuhiro Shibata
High-resolution characterization of a hepatocellular carcinoma genome.
Nature genetics 2011;43(5):464-9.
2011: Junko Kikuchi; Ichiro Kinoshita; Yasushi Shimizu; Eiki Kikuchi; Kayoko Takeda; Hiroyuki Aburatani; Satoshi Oizumi; Jun Konishi; Kichizo Kaga; Yoshihiro Matsuno; Michael J Birrer; Masaharu Nishimura; Hirotoshi Dosaka-Akita
Minichromosome maintenance (MCM) protein 4 as a marker for proliferation and its clinical and clinicopathological significance in non-small cell lung cancer.
Lung cancer (Amsterdam, Netherlands) 2011;72(2):229-37.
2011: Tomonori Muraoka; Kazutaka Aoki; Tomoyuki Iwasaki; Kazuaki Shinoda; Akinobu Nakamura; Hiroyuki Aburatani; Shuuichi Mori; Kumpei Tokuyama; Naoto Kubota; Takashi Kadowaki; Yasuo Terauchi
Ezetimibe decreases SREBP-1c expression in liver and reverses hepatic insulin resistance in mice fed a high-fat diet.
Metabolism: clinical and experimental 2011;60(5):617-28.
2011: Kojiro Sato; Fumihiko Miyoshi; Kazuhiro Yokota; Yasuto Araki; Yu Asanuma; Yuji Akiyama; Keigyou Yoh; Satoru Takahashi; Hiroyuki Aburatani; Toshihide Mimura
Marked induction of c-Maf protein during Th17 cell differentiation and its implication in memory Th cell development.
The Journal of biological chemistry 2011;286(17):14963-71.
2011: S Ehata; E Johansson; R Katayama; Satoshi Koike; Akira Watanabe; Yuichi Hoshino; Y Katsuno; Akiyoshi Komuro; D Koinuma; Mitsunobu R Kano; M Yashiro; K Hirakawa; Hiroyuki Aburatani; N Fujita; Kohei Miyazono
Transforming growth factor-β decreases the cancer-initiating cell population within diffuse-type gastric carcinoma cells.
Oncogene 2011;30(14):1693-705.
2011: Yasuo Ouchi; Yukihiro Baba; Hideto Koso; Makoto M Taketo; Takashi Iwamoto; Hiroyuki Aburatani; Sumiko Watanabe
β-Catenin signaling regulates the timing of cell differentiation in mouse retinal progenitor cells.
Molecular and cellular neurosciences 2011;46(4):770-80.
2011: Kenji Daigo; Takeshi Kawamura; Y Ohta; Riuko Ohashi; Satoshi Katayose; Toshiya Tanaka; Hiroyuki Aburatani; Makoto Naito; Tatsuhiko Kodama; Sigeo Ihara; Takao Hamakubo
Proteomic analysis of native hepatocyte nuclear factor-4α (HNF4α) isoforms, phosphorylation status, and interactive cofactors.
The Journal of biological chemistry 2011;286(1):674-86.
2011: Takuma Hayashi; Nobuyoshi Hiraoka; Akiko Horiuchi; Tomoyuki Ichimura; Osamu Ishiko; Yae Kanai; Mari Kasai; Ryuichiro Nishimura; Kenji Sano; Tanri Shiozawa; Tamotsu Sudo; Yoh-Ichi Tagawa; Nobuo Yaegashi; Hiroyuki Aburatani; Ikuo Konishi
Potential role of LMP2 as tumor-suppressor defines new targets for uterine leiomyosarcoma therapy.
Scientific reports 2011;1():180.
2011: Ken Matsuura; Yasuyuki Morishita; Tsutomu Nakamura; Aya Nonaka; Takao Senda; Kenzui Taniue; Hiroyuki Aburatani; Shungo Adachi; Takafumi Jigami; Tetsu Akiyama
Identification of a link between Wnt/β-catenin signalling and the cell fusion pathway.
Nature communications 2011;2():548.
2011: Takayuki Isagawa; Shumpei Ishikawa; Shoen Kume; Genta Nagae; Noriko Sato; Nobuaki Shiraki; Takanori Fujita; Hiroyuki Aburatani
DNA methylation profiling of embryonic stem cell differentiation into the three germ layers.
PloS one 2011;6(10):e26052.
2011: Satoshi Sugita; Miki Tadaishi; Takako Takai-Igarashi; Yoshifumi Tamura; Tetsuya Yamada; Jun-ichiro Oka; Takayoshi Suganami; Hiroyuki Aburatani; Fumiko Akaike; Osamu Ezaki; Nobuharu Fujii; Maki Hattori; Saori Kakehi; Yasutomi Kamei; Sayaka Kanai; Hideki Katagiri; Hideo Kubo; Yasuko Manabe; Shinji Miura; Kenichi Nishida; Yoshihiro Ogawa
Increased systemic glucose tolerance with increased muscle glucose uptake in transgenic mice overexpressing RXRγ in skeletal muscle.
PloS one 2011;6(5):e20467.
2011: Hiroyuki Aburatani
[Cancer genome analysis through next-generation sequencing].
Gan to kagaku ryoho. Cancer & chemotherapy 2011;38(1):1-6.
2010: Toru Shinoe; Hiroshi Kuribayashi; Hideyuki Saya; Motoharu Seiki; Hiroyuki Aburatani; Sumiko Watanabe
Identification of CD44 as a cell surface marker for Müller glia precursor cells.
Journal of neurochemistry 2010;115(6):1633-42.
2010: Chisato Fujimoto; Hidenori Ozeki; Yasunobu Uchijima; Keigo Suzukawa; Akihisa Mitani; Shigetomo Fukuhara; Koichi Nishiyama; Yukiko Kurihara; Kenji Kondo; Hiroyuki Aburatani; Kimitaka Kaga; Tatsuya Yamasoba; Hiroki Kurihara
Establishment of mice expressing EGFP in the placode-derived inner ear sensory cell lineage and FACS-array analysis focused on the regional specificity of the otocyst.
The Journal of comparative neurology 2010;518(23):4702-22.
2010: Fumiyuki Hatanaka; Chiaki Matsubara; Jihwan Myung; Takashi Yoritaka; Naoko Kamimura; Shuichi Tsutsumi; Akinori Kanai; Yutaka Suzuki; Paolo Sassone-Corsi; Hiroyuki Aburatani; Sumio Sugano; Toru Takumi
Genome-wide profiling of the core clock protein BMAL1 targets reveals a strict relationship with metabolism.
Molecular and cellular biology 2010;30(24):5636-48.
2010: Chihiro Akimoto; Takashi Ueda; Kazuki Inoue; Ikuko Yamaoka; Matomo Sakari; Wataru Obara; Tomoaki Fujioka; Akira Nagahara; Norio Nonomura; Syuichi Tsutsumi; Hiroyuki Aburatani; Tsuneharu Miki; Takahiro Matsumoto; Hirochika Kitagawa; Shigeaki Kato
Testis-specific protein on Y chromosome (TSPY) represses the activity of the androgen receptor in androgen-dependent testicular germ-cell tumors.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(46):19891-6.
2010: Daisuke Matsubara; Shumpei Ishikawa; Oguni Sachiko; Hiroyuki Aburatani; Masashi Fukayama; Toshiro Niki
Co-activation of epidermal growth factor receptor and c-MET defines a distinct subset of lung adenocarcinomas.
The American journal of pathology 2010;177(5):2191-204.
2010: Erik Johansson; Akiyoshi Komuro; Caname Iwata; Akifumi Hagiwara; Yuma Fuse; Akira Watanabe; Yasuyuki Morishita; Hiroyuki Aburatani; Keiko Funa; Mitsunobu R Kano; Kohei Miyazono
Exogenous introduction of tissue inhibitor of metalloproteinase 2 reduces accelerated growth of TGF-β-disrupted diffuse-type gastric carcinoma.
Cancer science 2010;101(11):2398-403.
2010: Yuichiro Ihara; Yasuyuki Kihara; Fumie Hamano; Keisuke Yanagida; Yasuyuki Morishita; Akiko Kunita; Takao Yamori; Masashi Fukayama; Hiroyuki Aburatani; Takao Shimizu; Satoshi Ishii
The G protein-coupled receptor T-cell death-associated gene 8 (TDAG8) facilitates tumor development by serving as an extracellular pH sensor.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(40):17309-14.
2010: Daisuke Matsubara; Shumpei Ishikawa; Sachiko Oguni; Hiroyuki Aburatani; Masashi Fukayama; Toshiro Niki
Molecular predictors of sensitivity to the MET inhibitor PHA665752 in lung carcinoma cells.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 2010;5(9):1317-24.
2010: Hiroyuki Aburatani
[Epigenetic analysis].
Nihon rinsho. Japanese journal of clinical medicine 2010;68 Suppl 8():242-9.
2010: Jun Mitsui; Yuji K Takahashi; Jun Goto; Hiroyuki Tomiyama; Shunpei Ishikawa; Hiroyo Yoshino; Narihiro Minami; David I Smith; Suzanne Lesage; Hiroyuki Aburatani; Ichizo Nishino; Alexis Brice; Nobutaka Hattori; Shoji Tsuji
Mechanisms of genomic instabilities underlying two common fragile-site-associated loci, PARK2 and DMD, in germ cell and cancer cell lines.
American journal of human genetics 2010;87(1):75-89.
2010: Motoaki Seki; Akira Watanabe; Satoshi Enomoto; Takeshi Kawamura; Hirotaka Ito; Tatsuhiko Kodama; Takao Hamakubo; Hiroyuki Aburatani
Human ROBO1 is cleaved by metalloproteinases and gamma-secretase and migrates to the nucleus in cancer cells.
FEBS letters 2010;584(13):2909-15.
2010: Hyuk-Joon Lee; Ki Taek Nam; Heae Surng Park; Min A Kim; Bonnie J Lafleur; Hiroyuki Aburatani; Han-Kwang Yang; Woo Ho Kim; James R Goldenring
Gene expression profiling of metaplastic lineages identifies CDH17 as a prognostic marker in early stage gastric cancer.
Gastroenterology 2010;139(1):213-25.e3.
2010: Ying-Bing Deng; Genta Nagae; Yutaka Midorikawa; Koichi Yagi; Shuichi Tsutsumi; Shogo Yamamoto; Kiyoshi Hasegawa; Norihiro Kokudo; Hiroyuki Aburatani; Atsushi Kaneda
Identification of genes preferentially methylated in hepatitis C virus-related hepatocellular carcinoma.
Cancer science 2010;101(6):1501-10.
2010: Keiji Nakajima; Yusuke Komiyama; Hironori Hojo; Shinsuke Ohba; Fumiko Yano; Naoko Nishikawa; Sigeo Ihara; Hiroyuki Aburatani; Tsuyoshi Takato; Ung-il Chung
Enhancement of bone formation ex vivo and in vivo by a helioxanthin-derivative.
Biochemical and biophysical research communications 2010;395(4):502-8.
2010: Shogo Yamamoto; Yutaka Midorikawa; Teppei Morikawa; Yoji Nishimura; Hirohiko Sakamoto; Shumpei Ishikawa; Kiwamu Akagi; Hiroyuki Aburatani
Identification of chromosomal aberrations of metastatic potential in colorectal carcinoma.
Genes, chromosomes & cancer 2010;49(5):487-96.
2010: Takashi Fujino; Kimie Nomura; Yuichi Ishikawa; Hatsune Makino; Akihiro Umezawa; Hiroyuki Aburatani; Koichi Nagasaki; Takuro Nakamura
Function of EWS-POU5F1 in sarcomagenesis and tumor cell maintenance.
The American journal of pathology 2010;176(4):1973-82.
2010: S Murayama-Hosokawa; K Oda; S Nakagawa; S Ishikawa; S Yamamoto; K Shoji; Yasuo Ikeda; Yoshimasa Uehara; M Fukayama; F McCormick; T Yano; Y Taketani; Hiroyuki Aburatani
Genome-wide single-nucleotide polymorphism arrays in endometrial carcinomas associate extensive chromosomal instability with poor prognosis and unveil frequent chromosomal imbalances involved in the PI3-kinase pathway.
Oncogene 2010;29(13):1897-908.
2010: Mamoru Kato; Takahisa Kawaguchi; Shumpei Ishikawa; Takayoshi Umeda; Reiichiro Nakamichi; Michael H Shapero; Keith W Jones; Yusuke Nakamura; Hiroyuki Aburatani; Tatsuhiko Tsunoda
Population-genetic nature of copy number variations in the human genome.
Human molecular genetics 2010;19(5):761-73.
2010: Hozumi Motohashi; Momoko Kimura; Rie Fujita; Ai Inoue; Xiaoqing Pan; Mariko Takayama; Fumiki Katsuoka; Hiroyuki Aburatani; Emery H Bresnick; Masayuki Yamamoto
NF-E2 domination over Nrf2 promotes ROS accumulation and megakaryocytic maturation.
Blood 2010;115(3):677-86.
2010: M Murohashi; K Hinohara; M Kuroda; Takayuki Isagawa; Shingo Tsuji; S Kobayashi; Kazuo Umezawa; A Tojo; Hiroyuki Aburatani; N Gotoh
Gene set enrichment analysis provides insight into novel signalling pathways in breast cancer stem cells.
British journal of cancer 2010;102(1):206-12.
2010: Toshihiko Inowa; Keiichi Hishikawa; Yumi Matsuzaki; Takayuki Isagawa; Takumi Takeuchi; Hiroyuki Aburatani; Tadaichi Kitamura; Toshiro Fujita
GADD45β Determines Chemoresistance and Invasive Growth of Side Population Cells of Human Embryonic Carcinoma.
Stem cells international 2010;2010():782967.
2010: Hiromi Nishida; Takayuki Motoyama; Yutaka Suzuki; Shogo Yamamoto; Hiroyuki Aburatani; Hiroyuki Osada
Genome-wide maps of mononucleosomes and dinucleosomes containing hyperacetylated histones of Aspergillus fumigatus.
PloS one 2010;5(3):e9916.
2010: Koichi Yagi; Kiwamu Akagi; Hiroshi Hayashi; Genta Nagae; Shingo Tsuji; Takayuki Isagawa; Yutaka Midorikawa; Y Nishimura; Hirohiko Sakamoto; Yasuyuki Seto; Hiroyuki Aburatani; Atsushi Kaneda
Three DNA methylation epigenotypes in human colorectal cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2010;16(1):21-33.
2010: Yutaka Midorikawa; Yasuyuki Sugiyama; Hiroyuki Aburatani
Molecular targets for liver cancer therapy: From screening of target genes to clinical trials.
Hepatology research : the official journal of the Japan Society of Hepatology 2010;40(1):49-60.
2009: Yukiko Kawashiro; Hideki Fukata; Koji Sato; Hiroyuki Aburatani; Hidetaka Takigami; Chisato Mori
Polybrominated diphenyl ethers cause oxidative stress in human umbilical vein endothelial cells.
Human & experimental toxicology 2009;28(11):703-13.
2009: Daizo Koinuma; Shuichi Tsutsumi; Naoko Kamimura; Takeshi Imamura; Hiroyuki Aburatani; Kohei Miyazono
Promoter-wide analysis of Smad4 binding sites in human epithelial cells.
Cancer science 2009;100(11):2133-42.
2009: Youichiro Wada; Yoshihiro Ohta; Meng Xu; Shuichi Tsutsumi; Takashi Minami; Kenji Inoue; Daisuke Komura; Jun'ichi Kitakami; Nobuhiko Oshida; Argyris Papantonis; Akashi Izumi; Mika Kobayashi; Hiroko Meguro; Yasuharu Kanki; Imari Mimura; Kazuki Yamamoto; Chikage Mataki; Takao Hamakubo; Katsuhiko Shirahige; Hiroyuki Aburatani; Hiroshi Kimura; Tatsuhiko Kodama; Peter R Cook; Sayoko Ihara
A wave of nascent transcription on activated human genes.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(43):18357-61.
2009: Yasutaka Inuzuka; Junji Okuda; Tsuneaki Kawashima; Takao Kato; Shinichiro Niizuma; Yodo Tamaki; Yoshitaka Iwanaga; Yuki Yoshida; Rie Kosugi; Kayo Watanabe-Maeda; Yoji Machida; Shingo Tsuji; Hiroyuki Aburatani; Tohru Izumi; Toru Kita; Tetsuo Shioi
Suppression of phosphoinositide 3-kinase prevents cardiac aging in mice.
Circulation 2009;120(17):1695-703.
2009: Yuichi Abe; Akira Oka; Masashi Mizuguchi; Takashi Igarashi; S Ishikawa; Hiroyuki Aburatani; Shigetoshi Yokoyama; Hiroshi Asahara; Kazuaki Nagao; Masao Yamada; Toshiyuki Miyashita
EYA4, deleted in a case with middle interhemispheric variant of holoprosencephaly, interacts with SIX3 both physically and functionally.
Human mutation 2009;30(10):E946-55.
2009: Hiromi Nishida; Takayuki Motoyama; Shogo Yamamoto; Hiroyuki Aburatani; Hiroyuki Osada
Genome-wide maps of mono- and di-nucleosomes of Aspergillus fumigatus.
Bioinformatics (Oxford, England) 2009;25(18):2295-7.
2009: Akihisa Mitani; Takahide Nagase; Kazunori Fukuchi; Hiroyuki Aburatani; Ryosuke Makita; Hiroki Kurihara
Transcriptional coactivator with PDZ-binding motif is essential for normal alveolarization in mice.
American journal of respiratory and critical care medicine 2009;180(4):326-38.
2009: Youichi Sato; Toshikatsu Shinka; Gang Chen; Hong-Tao Yan; Kozue Sakamoto; Ashraf A Ewis; Hiroyuki Aburatani; Yutaka Nakahori
Proteomics and transcriptome approaches to investigate the mechanism of human sex determination.
Cell biology international 2009;33(8):839-47.
2009: K Shoji; Katsutoshi Oda; Shunsuke Nakagawa; S Hosokawa; G Nagae; Yoshimasa Uehara; K Sone; Yusei Miyamoto; H Hiraike; O Hiraike-Wada; Tomomi Nei; Kei Kawana; Hiroyuki Kuramoto; Hiroyuki Aburatani; Tetsu Yano; Yuji Taketani
The oncogenic mutation in the pleckstrin homology domain of AKT1 in endometrial carcinomas.
British journal of cancer 2009;101(1):145-8.
2009: Yosuke Kayama; Tohru Minamino; Haruhiro Toko; Masaya Sakamoto; Ippei Shimizu; Hidehisa Takahashi; Sho Okada; Kaoru Tateno; Junji Moriya; Masataka Yokoyama; Aika Nojima; Michihiro Yoshimura; Kensuke Egashira; Hiroyuki Aburatani; Issei Komuro
Cardiac 12/15 lipoxygenase-induced inflammation is involved in heart failure.
The Journal of experimental medicine 2009;206(7):1565-74.
2009: Kyoko Yoneda; Hiroshi Iida; Hiroki Endo; Kunihiro Hosono; Tomoyuki Akiyama; Hirokazu Takahashi; Masahiko Inamori; Yasunobu Abe; Masato Yoneda; Koji Fujita; Shingo Kato; Yuichi Nozaki; Yasushi Ichikawa; Hiroshi Uozaki; Masashi Fukayama; Takahiro Shimamura; Tatsuhiko Kodama; Hiroyuki Aburatani; Chihiro Miyazawa; Keisuke Ishii; Naoki Hosomi; Mina Sagara; Masazumi Takahashi; Hideyuki Ike; Hiroaki Saito; Akihiko Kusakabe; Atsushi Nakajima
Identification of Cystatin SN as a novel tumor marker for colorectal cancer.
International journal of oncology 2009;35(1):33-40.
2009: Ken-ichi Wakabayashi; Masashi Okamura; Shuichi Tsutsumi; Naoko S Nishikawa; Toshiya Tanaka; Iori Sakakibara; Jun-ichi Kitakami; Sigeo Ihara; Yuichi Hashimoto; Takao Hamakubo; Tatsuhiko Kodama; Hiroyuki Aburatani; Juro Sakai
The peroxisome proliferator-activated receptor gamma/retinoid X receptor alpha heterodimer targets the histone modification enzyme PR-Set7/Setd8 gene and regulates adipogenesis through a positive feedback loop.
Molecular and cellular biology 2009;29(13):3544-55.
2009: Hiroyuki Aburatani
[Genomic technologies in medicine].
Nihon rinsho. Japanese journal of clinical medicine 2009;67(6):1156-63.
2009: Daichi Maeda; Satoshi Ota; Yutaka Takazawa; Hiroyuki Aburatani; Shunsuke Nakagawa; Tetsu Yano; Yuji Taketani; Tatsuhiko Kodama; Masashi Fukayama
Glypican-3 expression in clear cell adenocarcinoma of the ovary.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2009;22(6):824-32.
2009: Sunao Sugita; Yoshihiko Usui; Shintaro Horie; Yuri Futagami; Hiroyuki Aburatani; Taku Okazaki; Tasuku Honjo; Masaru Takeuchi; Manabu Mochizuki
T-cell suppression by programmed cell death 1 ligand 1 on retinal pigment epithelium during inflammatory conditions.
Investigative ophthalmology & visual science 2009;50(6):2862-70.
2009: Tsuyoshi Mishiro; Ko Ishihara; Shinjiro Hino; Shuichi Tsutsumi; Hiroyuki Aburatani; Katsuhiko Shirahige; Yoshikazu Kinoshita; Mitsuyoshi Nakao
Architectural roles of multiple chromatin insulators at the human apolipoprotein gene cluster.
The EMBO journal 2009;28(9):1234-45.
2009: Nobuaki Shiraki; Yuichiro Higuchi; Seiko Harada; Kahoko Umeda; Takayuki Isagawa; Hiroyuki Aburatani; Kazuhiko Kume; Shoen Kume
Differentiation and characterization of embryonic stem cells into three germ layers.
Biochemical and biophysical research communications 2009;381(4):694-9.
2009: Akiyoshi Komuro; Masakazu Yashiro; Caname Iwata; Yasuyuki Morishita; Erik Johansson; Yoshiko Matsumoto; Akira Watanabe; Hiroyuki Aburatani; Hiroyuki Miyoshi; Ken Kiyono; Yo-taro Shirai; Hiroshi I Suzuki; Kosei Hirakawa; Mitsunobu R Kano; Kohei Miyazono
Diffuse-type gastric carcinoma: progression, angiogenesis, and transforming growth factor beta signaling.
Journal of the National Cancer Institute 2009;101(8):592-604.
2009: Masashi Okamura; Hiromi Kudo; Ken-ichi Wakabayashi; Toshiya Tanaka; Aya Nonaka; Aoi Uchida; Shuichi Tsutsumi; Iori Sakakibara; Makoto Naito; Timothy F Osborne; Takao Hamakubo; Sadayoshi Ito; Hiroyuki Aburatani; Masashi Yanagisawa; Tatsuhiko Kodama; Juro Sakai
COUP-TFII acts downstream of Wnt/beta-catenin signal to silence PPARgamma gene expression and repress adipogenesis.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(14):5819-24.
2009: Shunsuke Yuri; Sayoko Fujimura; Keisuke Nimura; Naoki Takeda; Yayoi Toyooka; Yu-Ichi Fujimura; Hiroyuki Aburatani; Kiyoe Ura; Haruhiko Koseki; Hitoshi Niwa; Ryuichi Nishinakamura
Sall4 is essential for stabilization, but not for pluripotency, of embryonic stem cells by repressing aberrant trophectoderm gene expression.
Stem cells (Dayton, Ohio) 2009;27(4):796-805.
2009: Tetsuo Ushiku; Hiroshi Uozaki; Aya Shinozaki; Satoshi Ota; Keisuke Matsuzaka; Sachiyo Nomura; Michio Kaminishi; Hiroyuki Aburatani; Tatsuhiko Kodama; Masashi Fukayama
Glypican 3-expressing gastric carcinoma: distinct subgroup unifying hepatoid, clear-cell, and alpha-fetoprotein-producing gastric carcinomas.
Cancer science 2009;100(4):626-32.
2009: Kiyo-aki Ishii; Toshio Fumoto; Kazuhiro Iwai; Sunao Takeshita; Masako Ito; Nobuyuki Shimohata; Hiroyuki Aburatani; Shigeru Taketani; Christopher J Lelliott; antonio vidal-puig; Kyoji Ikeda
Coordination of PGC-1beta and iron uptake in mitochondrial biogenesis and osteoclast activation.
Nature medicine 2009;15(3):259-66.
2009: Kiriko Kaneko; Kazumichi Furuyama; Hiroyuki Aburatani; Shigeki Shibahara
Hypoxia induces erythroid-specific 5-aminolevulinate synthase expression in human erythroid cells through transforming growth factor-beta signaling.
The FEBS journal 2009;276(5):1370-82.
2009: Tatsuya Kawase; Rieko Ohki; Tatsuhiro Shibata; Shuichi Tsutsumi; Naoko Kamimura; Johji Inazawa; Tsutomu Ohta; Hitoshi Ichikawa; Hiroyuki Aburatani; Fumio Tashiro; Yoichi Taya
PH domain-only protein PHLDA3 is a p53-regulated repressor of Akt.
Cell 2009;136(3):535-50.
2009: Subhash C Chauhan; Kelley Vannatta; Mara C Ebeling; Namita Vinayek; Akira Watanabe; Krishan Pandey; Maria C Bell; Michael D Koch; Hiroyuki Aburatani; Yuhlong Lio; Meena Jaggi
Expression and functions of transmembrane mucin MUC13 in ovarian cancer.
Cancer research 2009;69(3):765-74.
2009: Ichiro Kojima; Tetsuhiro Tanaka; Reiko Inagi; Hiroshi Nishi; Hiroyuki Aburatani; Hideki Kato; Toshio Miyata; Toshiro Fujita; Masaomi Nangaku
Metallothionein is upregulated by hypoxia and stabilizes hypoxia-inducible factor in the kidney.
Kidney international 2009;75(3):268-77.
2009: Yutaka Midorikawa; Shogo Yamamoto; Shingo Tsuji; Naoko Kamimura; Shumpei Ishikawa; Hisaki Igarashi; Makuuchi Masatoshi; Norihiro Kokudo; Haruhiko Sugimura; Hiroyuki Aburatani
Allelic imbalances and homozygous deletion on 8p23.2 for stepwise progression of hepatocarcinogenesis.
Hepatology (Baltimore, Md.) 2009;49(2):513-22.
2009: Kiyotaka Nakano; Tetsuro Orita; Junichi Nezu; Takeshi Yoshino; Iwao Ohizumi; Masamichi Sugimoto; Koh Furugaki; Yasuko Kinoshita; Takahiro Ishiguro; Takao Hamakubo; Tatsuhiko Kodama; Hiroyuki Aburatani; Hisafumi Yamada-Okabe; Masayuki Tsuchiya
Anti-glypican 3 antibodies cause ADCC against human hepatocellular carcinoma cells.
Biochemical and biophysical research communications 2009;378(2):279-84.
2009: Kenji Matsumoto; Takayuki Isagawa; Toshinobu Nishimura; Takunori Ogaeri; Koji Eto; Satsuki Miyazaki; Jun-ichi Miyazaki; Hiroyuki Aburatani; Hiromitsu Nakauchi; Hideo Ema
Stepwise development of hematopoietic stem cells from embryonic stem cells.
PloS one 2009;4(3):e4820.
2009: Atsushi Niida; Andrew D Smith; Seiya Imoto; Hiroyuki Aburatani; Michael Q Zhang; Tetsu Akiyama
Gene set-based module discovery in the breast cancer transcriptome.
BMC bioinformatics 2009;10():71.
2009: Ken-ichi Takayama; Shuichi Tsutsumi; Takashi Suzuki; Kuniko Horie-Inoue; Kazuhiro Ikeda; Kiyofumi Kaneshiro; Tetsuya Fujimura; Jiro Kumagai; Tomohiko Urano; Yoshiyuki Sakaki; Katsuhiko Shirahige; Hironobu Sasano; Satoru Takahashi; Tadaichi Kitamura; Yasuyoshi Ouchi; Hiroyuki Aburatani; Satoshi Inoue
Amyloid precursor protein is a primary androgen target gene that promotes prostate cancer growth.
Cancer research 2009;69(1):137-42.
2009: Hiromi Takanaga; Nobuko Tsuchida-Straeten; Kenji Nishide; Akira Watanabe; Hiroyuki Aburatani; Toru Kondo
Gli2 is a novel regulator of sox2 expression in telencephalic neuroepithelial cells.
Stem cells (Dayton, Ohio) 2009;27(1):165-74.
2008: Takahiro Ishiguro; Masamichi Sugimoto; Yasuko Kinoshita; Yoko Miyazaki; Kiyotaka Nakano; Hiroyuki Tsunoda; Izumi Sugo; Iwao Ohizumi; Hiroyuki Aburatani; Takao Hamakubo; Tatsuhiko Kodama; Masayuki Tsuchiya; Hisafumi Yamada-Okabe
Anti-glypican 3 antibody as a potential antitumor agent for human liver cancer.
Cancer research 2008;68(23):9832-8.
2008: Sunao Sugita; Shintaro Horie; Orie Nakamura; Yuri Futagami; Hiroshi Takase; Hiroshi Keino; Hiroyuki Aburatani; Nobuhiko Katunuma; Kazumi Ishidoh; Yoshimi Yamamoto; Manabu Mochizuki
Retinal pigment epithelium-derived CTLA-2alpha induces TGFbeta-producing T regulatory cells.
Journal of immunology (Baltimore, Md. : 1950) 2008;181(11):7525-36.
2008: Takeshi Shimizu; Tetsushi Kagawa; Toshihiro Inoue; Aya Nonaka; Shinji Takada; Hiroyuki Aburatani; Tetsuya Taga
Stabilized beta-catenin functions through TCF/LEF proteins and the Notch/RBP-Jkappa complex to promote proliferation and suppress differentiation of neural precursor cells.
Molecular and cellular biology 2008;28(24):7427-41.
2008: Masato Yoneda; Hiroki Endo; Hironori Mawatari; Yuichi Nozaki; Koji Fujita; Tomoyuki Akiyama; Takuma Higurashi; Takashi Uchiyama; Kyoko Yoneda; Hirokazu Takahashi; Hiroyuki Kirikoshi; Masahiko Inamori; Yasunobu Abe; Kensuke Kubota; Satoru Saito; Noritoshi Kobayashi; Naotaka Yamaguchi; Shiro Maeyama; Shogo Yamamoto; Shuichi Tsutsumi; Hiroyuki Aburatani; Koichiro Wada; Kikuko Hotta; Atsushi Nakajima
Gene expression profiling of non-alcoholic steatohepatitis using gene set enrichment analysis.
Hepatology research : the official journal of the Japan Society of Hepatology 2008;38(12):1204-12.
2008: Makiko Ohtsuji; Fumiki Katsuoka; Akira Kobayashi; Hiroyuki Aburatani; John D Hayes; Masayuki Yamamoto
Nrf1 and Nrf2 play distinct roles in activation of antioxidant response element-dependent genes.
The Journal of biological chemistry 2008;283(48):33554-62.
2008: Sachie Hiratsuka; Akira Watanabe; Yoshiko Sakurai; Sachiko Akashi-Takamura; Sachie Ishibashi; Kensuke Miyake; Masabumi Shibuya; Shizuo Akira; Hiroyuki Aburatani; Yoshiro Maru
The S100A8-serum amyloid A3-TLR4 paracrine cascade establishes a pre-metastatic phase.
Nature cell biology 2008;10(11):1349-55.
2008: Takuma Matsubara; Kumiko Kida; Akira Yamaguchi; Kenji Hata; Fumitaka Ichida; Hiroko Meguro; Hiroyuki Aburatani; Riko Nishimura; Toshiyuki Yoneda
BMP2 regulates Osterix through Msx2 and Runx2 during osteoblast differentiation.
The Journal of biological chemistry 2008;283(43):29119-25.
2008: Yasuko Onuma; Akira Watanabe; Hiroyuki Aburatani; Makoto Asashima; Malcolm Whitman
TRIQK, a novel family of small proteins localized to the endoplasmic reticulum membrane, is conserved across vertebrates.
Zoological science 2008;25(7):706-13.
2008: Yutaka Midorikawa; Yasuyuki Sugiyama; Hiroyuki Aburatani
Screening of liver-targeted drugs.
Expert opinion on drug discovery 2008;3(6):643-54.
2008: Yuichi Torisu; Akira Watanabe; Aya Nonaka; Yutaka Midorikawa; Makuuchi Masatoshi; Takahiro Shimamura; Haruhiko Sugimura; Atsushi Niida; Tetsu Akiyama; Hiroko Iwanari; Tatsuhiko Kodama; Mikio Zeniya; Hiroyuki Aburatani
Human homolog of NOTUM, overexpressed in hepatocellular carcinoma, is regulated transcriptionally by beta-catenin/TCF.
Cancer science 2008;99(6):1139-46.
2008: Akihiko Taguchi; Masahiro Emoto; Shigeru Okuya; Naofumi Fukuda; Yoshitaka Nakamori; Mutsuko Miyazaki; Sachiko Miyamoto; Katsuya Tanabe; Hiroyuki Aburatani; Yoshitomo Oka; Yukio Tanizawa
Identification of Glypican3 as a novel GLUT4-binding protein.
Biochemical and biophysical research communications 2008;369(4):1204-8.
2008: Yasutomi Kamei; Shinji Miura; Takayoshi Suganami; Fumiko Akaike; Sayaka Kanai; Satoshi Sugita; Aki Katsumata; Hiroyuki Aburatani; Terry G Unterman; Osamu Ezaki; Yoshihiro Ogawa
Regulation of SREBP1c gene expression in skeletal muscle: role of retinoid X receptor/liver X receptor and forkhead-O1 transcription factor.
Endocrinology 2008;149(5):2293-305.
2008: Suguru Yamaguchi; Hisamitsu Ishihara; Takahiro Yamada; Akira Tamura; Masahiro Usui; Ryu Tominaga; Yuichiro Munakata; Chihiro Satake; Hideki Katagiri; Fumi Tashiro; Hiroyuki Aburatani; Kyoko Tsukiyama-Kohara; Jun-ichi Miyazaki; Nahum Sonenberg; Yoshitomo Oka
ATF4-mediated induction of 4E-BP1 contributes to pancreatic beta cell survival under endoplasmic reticulum stress.
Cell metabolism 2008;7(3):269-76.
2008: Ryosuke Makita; Yasunobu Uchijima; Koichi Nishiyama; Tomokazu Amano; Qin Chen; Takumi Takeuchi; Akihisa Mitani; Takahide Nagase; Yutaka Yatomi; Hiroyuki Aburatani; Osamu Nakagawa; Erin V Small; Patricia Cobo-Stark; Peter Igarashi; Masao Murakami; Junji Tominaga; Takahiro Sato; Tomoichiro Asano; Yukiko Kurihara; Hiroki Kurihara
Multiple renal cysts, urinary concentration defects, and pulmonary emphysematous changes in mice lacking TAZ.
American journal of physiology. Renal physiology 2008;294(3):F542-53.
2008: Kerstin Wendt; Keisuke Yoshida; Takehiko Itoh; Masashige Bando; Birgit Koch; Erika Schirghuber; Shuichi Tsutsumi; Genta Nagae; Ko Ishihara; Tsuyoshi Mishiro; Kazuhide Yahata; Fumio Imamoto; Hiroyuki Aburatani; Mitsuyoshi Nakao; Naoko Imamoto; Kazuhiro Maeshima; Katsuhiko Shirahige; Jan-Michael Peters
Cohesin mediates transcriptional insulation by CCCTC-binding factor.
Nature 2008;451(7180):796-801.
2008: Makoto Hayashi; Shingo Maeda; Hiroyuki Aburatani; Kunio Kitamura; Hiroyuki Miyoshi; Kohei Miyazono; Takeshi Imamura
Pitx2 prevents osteoblastic transdifferentiation of myoblasts by bone morphogenetic proteins.
The Journal of biological chemistry 2008;283(1):565-71.
2008: Takuma Hayashi; Yuto Shimamura; Taro Saegusa; Akiko Horiuchi; Yukihiro Kobayashi; Nobuyoshi Hiraoka; Yae Kanai; Hiroyuki Aburatani; Kenji Sano; Ikuo Konishi
Molecular mechanisms of uterine leiomyosarcomas: involvement of defect in LMP2 expression.
Gene regulation and systems biology 2008;2():297-305.
2008: Masato Yoneda; Takashi Uchiyama; Shingo Kato; Hiroki Endo; Koji Fujita; Kyoko Yoneda; Hironori Mawatari; Hiroshi Iida; Hirokazu Takahashi; Hiroyuki Kirikoshi; Masahiko Inamori; Yuichi Nozaki; Noritoshi Kobayashi; Kensuke Kubota; Satoru Saito; Shiro Maeyama; Mina Sagara; Hiroyuki Aburatani; Tatsuhiko Kodama; Atsushi Nakajima
Plasma Pentraxin3 is a novel marker for nonalcoholic steatohepatitis (NASH).
BMC gastroenterology 2008;8():53.
2008: Atsushi Niida; Andrew D Smith; Seiya Imoto; Shuichi Tsutsumi; Hiroyuki Aburatani; Michael Q Zhang; Tetsu Akiyama
Integrative bioinformatics analysis of transcriptional regulatory programs in breast cancer cells.
BMC bioinformatics 2008;9():404.
2008: Chih-Ping Li; Akiteru Goto; Akira Watanabe; Kengo Murata; Satoshi Ota; Toshiro Niki; Hiroyuki Aburatani; Masashi Fukayama
AKR1B10 in usual interstitial pneumonia: expression in squamous metaplasia in association with smoking and lung cancer.
Pathology, research and practice 2008;204(5):295-304.
2008: Yu Nakamura; Daisuke Matsubara; Akiteru Goto; Satoshi Ota; Oguni Sachiko; Shumpei Ishikawa; Hiroyuki Aburatani; Keiji Miyazawa; Masashi Fukayama; Toshiro Niki
Constitutive activation of c-Met is correlated with c-Met overexpression and dependent on cell-matrix adhesion in lung adenocarcinoma cell lines.
Cancer science 2008;99(1):14-22.
2007: Hong-Tao Yan; Toshikatsu Shinka; Youichi Sato; Xin-Jun Yang; Gang Chen; Kozue Sakamoto; Keigo Kinoshita; Hiroyuki Aburatani; Yutaka Nakahori
Overexpression of SOX15 inhibits proliferation of NT2/D1 cells derived from a testicular embryonal cell carcinoma.
Molecules and cells 2007;24(3):323-8.
2007: Katsunori Fujii; Shumpei Ishikawa; Hideki Uchikawa; Daisuke Komura; Michael H Shapero; Fan Shen; Jing Hung; Hiroshi Arai; Yoko Tanaka; Kimio Sasaki; Yoichi Kohno; Masao Yamada; Keith W Jones; Hiroyuki Aburatani; Toshiyuki Miyashita
High-density oligonucleotide array with sub-kilobase resolution reveals breakpoint information of submicroscopic deletions in nevoid basal cell carcinoma syndrome.
Human genetics 2007;122(5):459-66.
2007: Kengo Murata; Satoshi Ota; Toshiro Niki; Akiteru Goto; Chih-Ping Li; Urbiztondo Maria Rhea Ruriko; Shumpei Ishikawa; Hiroyuki Aburatani; Takayuki Kuriyama; Masashi Fukayama
p63 - Key molecule in the early phase of epithelial abnormality in idiopathic pulmonary fibrosis.
Experimental and molecular pathology 2007;83(3):367-76.
2007: Momoko Kimura; Tae Yamamoto; Jianyong Zhang; Ken Itoh; Motoki Kyo; Terue Kamiya; Hiroyuki Aburatani; Fumiki Katsuoka; hirofumi kurokawa; Toshiyuki Tanaka; Hozumi Motohashi; Masayuki Yamamoto
Molecular basis distinguishing the DNA binding profile of Nrf2-Maf heterodimer from that of Maf homodimer.
The Journal of biological chemistry 2007;282(46):33681-90.
2007: Y Lu; Jiro Kitaura; Toshikazu Oki; Yukiko Komeno; Katsutoshi Ozaki; Mari Kiyono; Hidetoshi Kumagai; Hideaki Nakajima; Tetsuya Nosaka; Hiroyuki Aburatani; Toshio Kitamura
Identification of TSC-22 as a potential tumor suppressor that is upregulated by Flt3-D835V but not Flt3-ITD.
Leukemia 2007;21(11):2246-57.
2007: Shogo Ehata; Aki Hanyu; Makoto Hayashi; Hiroyuki Aburatani; Yukio Kato; Makoto Fujime; Masao Saitoh; Keiji Miyazawa; Takeshi Imamura; Kohei Miyazono
Transforming growth factor-beta promotes survival of mammary carcinoma cells through induction of antiapoptotic transcription factor DEC1.
Cancer research 2007;67(20):9694-703.
2007: Masashi Yoneda; Hiroki Endo; Yuichi Nozaki; Ayako Tomimoto; Toshio Fujisawa; Koji Fujita; Kyoko Yoneda; Hirokazu Takahashi; Satoru Saito; Tomoyuki Iwasaki; Shogo Yamamoto; Shuichi Tsutsumi; Hiroyuki Aburatani; Koichiro Wada; Kikuko Hotta; Atsushi Nakajima
Life style-related diseases of the digestive system: gene expression in nonalcoholic steatohepatitis patients and treatment strategies.
Journal of pharmacological sciences 2007;105(2):151-6.
2007: Teppei Morikawa; Akira Sugiyama; Haruki Kume; Satoshi Ota; Takeshi Kashima; Kyoichi Tomita; Tadaichi Kitamura; Tatsuhiko Kodama; Masashi Fukayama; Hiroyuki Aburatani
Identification of Toll-like receptor 3 as a potential therapeutic target in clear cell renal cell carcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2007;13(19):5703-9.
2007: Mikiko Inaki; Shingo Yoshikawa; John B Thomas; Hiroyuki Aburatani; Akinao Nose
Wnt4 is a local repulsive cue that determines synaptic target specificity.
Current biology : CB 2007;17(18):1574-9.
2007: Manabu Soda; Young Lim Choi; Munehiro Enomoto; Shuji Takada; Yoshihiro Yamashita; Shunpei Ishikawa; Shin-ichiro Fujiwara; Hideki Watanabe; Kentaro Kurashina; Hisashi Hatanaka; Masashi Bando; Shoji Ohno; Yuichi Ishikawa; Hiroyuki Aburatani; Toshiro Niki; Yasunori Sohara; Yukihiko Sugiyama; Hiroyuki Mano
Identification of the transforming EML4-ALK fusion gene in non-small-cell lung cancer.
Nature 2007;448(7153):561-6.
2007: Sunao Sugita; Yuri Futagami; Shintaro Horie; Hiroyuki Aburatani; Manabu Mochizuki
[Murine ciliary body pigment epithelial cells inhibit activation of T cells].
Nippon Ganka Gakkai zasshi 2007;111(8):598-605.
2007: Naoko Murata-Kamiya; Yo Kurashima; Yasuhiro Teishikata; Y Yamahashi; Y Saito; Hideaki Higashi; Hiroyuki Aburatani; T Akiyama; R M Peek; Takeshi Azuma; Masanori Hatakeyama
Helicobacter pylori CagA interacts with E-cadherin and deregulates the beta-catenin signal that promotes intestinal transdifferentiation in gastric epithelial cells.
Oncogene 2007;26(32):4617-26.
2007: K Takayama; Kiyofumi Kaneshiro; Shuichi Tsutsumi; Kuniko Horie-Inoue; K Ikeda; Tomohiko Urano; Nobuyuki Ijichi; Y Ouchi; Katsuhiko Shirahige; Hiroyuki Aburatani; Satoshi Inoue
Identification of novel androgen response genes in prostate cancer cells by coupling chromatin immunoprecipitation and genomic microarray analysis.
Oncogene 2007;26(30):4453-63.
2007: Hiromichi Narumiya; Kyoko Hidaka; Manabu Shirai; Hiromi Terami; Hiroyuki Aburatani; Takayuki Morisaki
Endocardiogenesis in embryoid bodies: novel markers identified by gene expression profiling.
Biochemical and biophysical research communications 2007;357(4):896-902.
2007: Yuri Futagami; Sunao Sugita; Jose Vega; Kazuhiro Ishida; Hiroshi Takase; Kazuichi Maruyama; Hiroyuki Aburatani; Manabu Mochizuki
Role of thrombospondin-1 in T cell response to ocular pigment epithelial cells.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(11):6994-7005.
2007: Tao Wang; Toshiro Niki; Akiteru Goto; Satoshi Ota; Teppei Morikawa; Yu Nakamura; Etsuko Ohara; Shumpei Ishikawa; Hiroyuki Aburatani; Jun Nakajima; Masashi Fukayama
Hypoxia increases the motility of lung adenocarcinoma cell line A549 via activation of the epidermal growth factor receptor pathway.
Cancer science 2007;98(4):506-11.
2007: Kazuo Tonami; Yukiko Kurihara; Hiroyuki Aburatani; Yasunobu Uchijima; Tomoichiro Asano; Hiroki Kurihara
Calpain 6 is involved in microtubule stabilization and cytoskeletal organization.
Molecular and cellular biology 2007;27(7):2548-61.
2007: Mariko Omori-Inoue; Hideki Fukata; Masatoshi Komiyama; Emiko Todaka; Hisao Osada; Hiroyuki Aburatani; Chisato Mori
The contamination levels of organochlorines and the pattern of gene expressions in human umbilical cords from intra-pairs of twins at delivery.
Reproductive toxicology (Elmsford, N.Y.) 2007;23(3):283-9.
2007: Hiromi Terami; Kyoko Hidaka; Manabu Shirai; Hiromichi Narumiya; Takuo Kuroyanagi; Yuji Arai; Hiroyuki Aburatani; Takayuki Morisaki
Efficient capture of cardiogenesis-associated genes expressed in ES cells.
Biochemical and biophysical research communications 2007;355(1):47-53.
2007: Nao Osaka; Takumi Takahashi; Shiori Murakami; Atsushi Matsuzawa; Takuya Noguchi; Takeshi Fujiwara; Hiroyuki Aburatani; Keiji Moriyama; Kohsuke Takeda; Hidenori Ichijo
ASK1-dependent recruitment and activation of macrophages induce hair growth in skin wounds.
The Journal of cell biology 2007;176(7):903-9.
2007: Yutaka Midorikawa; Makuuchi Masatoshi; Wei Tang; Hiroyuki Aburatani
Microarray-based analysis for hepatocellular carcinoma: from gene expression profiling to new challenges.
World journal of gastroenterology : WJG 2007;13(10):1487-92.
2007: Shinsuke Yoshizumi; Susumu Suzuki; Masashi Hirai; Yoshinori Hinokio; Tetsuya Yamada; Takahiro Yamada; Uiko Tsunoda; Hiroyuki Aburatani; Kazunori Yamaguchi; Taeko Miyagi; Yoshitomo Oka
Increased hepatic expression of ganglioside-specific sialidase, NEU3, improves insulin sensitivity and glucose tolerance in mice.
Metabolism: clinical and experimental 2007;56(3):420-9.
2007: Young Lim Choi; Kunihiro Tsukasaki; Michael C O'Neill; Yasuaki Yamada; Yasuyuki Onimaru; K Matsumoto; J Ohashi; Yoshihiro Yamashita; S Tsutsumi; Ruri Kaneda; Shuji Takada; Hiroyuki Aburatani; Shimeru Kamihira; T Nakamura; Masao Tomonaga; Hiroyuki Mano
A genomic analysis of adult T-cell leukemia.
Oncogene 2007;26(8):1245-55.
2007: Kiyofumi Kaneshiro; Shuichi Tsutsumi; Shingo Tsuji; Katsuhiko Shirahige; Hiroyuki Aburatani
An integrated map of p53-binding sites and histone modification in the human ENCODE regions.
Genomics 2007;89(2):178-88.
2007: Yoji Yamamoto; Akihiko Uehara; Kazuyuki Miura; Akira Watanabe; Hiroyuki Aburatani; Makoto Komiyama
Development of artificial restriction DNA cutter composed of Ce(Iv)/EDTA and PNA.
Nucleosides, nucleotides & nucleic acids 2007;26(10-12):1265-8.
2007: Yasuo Terauchi; Iseki Takamoto; Naoto Kubota; Junji Matsui; Ryo Suzuki; Kajuro Komeda; Akemi Hara; Yukiyasu Toyoda; Ichitomo Miwa; Shinichi Aizawa; Shuichi Tsutsumi; Yoshiharu Tsubamoto; Shinji Hashimoto; Kazuhiro Eto; Akinobu Nakamura; Mitsuhiko Noda; Kazuyuki Tobe; Hiroyuki Aburatani; Ryozo Nagai; Takashi Kadowaki
Glucokinase and IRS-2 are required for compensatory beta cell hyperplasia in response to high-fat diet-induced insulin resistance.
The Journal of clinical investigation 2007;117(1):246-57.
2007: Hiroshi Hayashi; Genta Nagae; Shuichi Tsutsumi; Kiyofumi Kaneshiro; Takazumi Kozaki; Atsushi Kaneda; Hajime Sugisaki; Hiroyuki Aburatani
High-resolution mapping of DNA methylation in human genome using oligonucleotide tiling array.
Human genetics 2007;120(5):701-11.
2006: Yingqiu Guo; Yongxin Chen; Hirotaka Ito; Akira Watanabe; Xijin Ge; Tatsuhiko Kodama; Hiroyuki Aburatani
Identification and characterization of lin-28 homolog B (LIN28B) in human hepatocellular carcinoma.
Gene 2006;384():51-61.
2006: Masaya Sakamoto; Tohru Minamino; Haruhiro Toko; Yosuke Kayama; Yunzeng Zou; Masanori Sano; Eiichi Takaki; Teruhiko Aoyagi; Katsuyoshi Tojo; Naoko Tajima; Akira Nakai; Hiroyuki Aburatani; Issei Komuro
Upregulation of heat shock transcription factor 1 plays a critical role in adaptive cardiac hypertrophy.
Circulation research 2006;99(12):1411-8.
2006: Sachie Hiratsuka; Akira Watanabe; Hiroyuki Aburatani; Yoshiro Maru
Tumour-mediated upregulation of chemoattractants and recruitment of myeloid cells predetermines lung metastasis.
Nature cell biology 2006;8(12):1369-75.
2006: Daisuke Komura; Fan Shen; Shumpei Ishikawa; Karen R Fitch; Wenwei Chen; Jane Zhang; Guoying Liu; Sayoko Ihara; Hiroshi Nakamura; Matthew E Hurles; Charles Lee; Stephen W Scherer; Keith W Jones; Michael H Shapero; Jing Huang; Hiroyuki Aburatani
Genome-wide detection of human copy number variations using high-density DNA oligonucleotide arrays.
Genome research 2006;16(12):1575-84.
2006: Razi Khaja; Junjun Zhang; Jeffrey R MacDonald; Yongshu He; Ann M Joseph-George; John Wei; Muhammad A Rafiq; Cheng Qian; Mary Shago; Lorena Pantano; Hiroyuki Aburatani; Keith Jones; Richard Redon; Matthew E Hurles; Lluis Armengol; Xavier Estivill; Richard J Mural; Charles Lee; Stephen W Scherer; Lars Feuk
Genome assembly comparison identifies structural variants in the human genome.
Nature genetics 2006;38(12):1413-8.
2006: Keiko Horiuchi; Michihisa Umetani; Takashi Minami; Hiroto Okayama; Shinji Takada; Masayuki Yamamoto; Hiroyuki Aburatani; Patrick C Reid; David E Housman; Takao Hamakubo; Tatsuhiko Kodama
Wilms' tumor 1-associating protein regulates G2/M transition through stabilization of cyclin A2 mRNA.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(46):17278-83.
2006: Hiroyuki Aburatani
[Genomic and epigenomic analysis using genome tiling arrays].
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 2006;51(14 Suppl):2006-12.
2006: Michiyo Hishinuma; K-I Ohashi; Naoko Yamauchi; Takeshi Kashima; Hiroshi Uozaki; Satoshi Ota; Tatsuhiko Kodama; Hiroyuki Aburatani; Masashi Fukayama
Hepatocellular oncofetal protein, glypican 3 is a sensitive marker for alpha-fetoprotein-producing gastric carcinoma.
Histopathology 2006;49(5):479-86.
2006: Yoshiyuki Takahara; Mitsuo Takahashi; Hiroki Wagatsuma; Fumihiko Yokoya; Qing-Wei Zhang; Mutsuyo Yamaguchi; Hiroyuki Aburatani; Norifumi Kawada
Gene expression profiles of hepatic cell-type specific marker genes in progression of liver fibrosis.
World journal of gastroenterology : WJG 2006;12(40):6473-99.
2006: Yutaka Midorikawa; S Yamamoto; S Ishikawa; N Kamimura; H Igarashi; H Sugimura; Makuuchi Masatoshi; Hiroyuki Aburatani
Molecular karyotyping of human hepatocellular carcinoma using single-nucleotide polymorphism arrays.
Oncogene 2006;25(40):5581-90.
2006: Hiroshi Hasegawa; Hiroyuki Takano; Kohro Takahide; Kazutaka Ueda; Yuriko Niitsuma; Hiroyuki Aburatani; Issei Komuro
Amelioration of hypertensive heart failure by amlodipine may occur via antioxidative effects.
Hypertension research : official journal of the Japanese Society of Hypertension 2006;29(9):719-29.
2006: Satoshi Ota; Michiyo Hishinuma; Naoko Yamauchi; Akiteru Goto; Teppei Morikawa; Tetsuya Fujimura; Tadaichi Kitamura; Tatsuhiko Kodama; Hiroyuki Aburatani; Masashi Fukayama
Oncofetal protein glypican-3 in testicular germ-cell tumor.
Virchows Archiv : an international journal of pathology 2006;449(3):308-14.
2006: Houjun Liu; Kazunori Urabe; Yoichi Moroi; Shinichiro Yasumoto; Hisashi Kokuba; Shinichi Imafuku; Tetsuya Koga; Teiichi Masuda; Hiroyuki Aburatani; masutaka furue; Yating Tu
Expression of p16 and hTERT protein is associated with the presence of high-risk human papillomavirus in Bowenoid papulosis.
Journal of cutaneous pathology 2006;33(8):551-8.
2006: Jennifer L Freeman; George H Perry; Lars Feuk; Richard Redon; Steven A McCarroll; David Altshuler; Hiroyuki Aburatani; Keith W Jones; Chris Tyler-Smith; Matthew E Hurles; Nigel P Carter; Stephen W Scherer; Charles Lee
Copy number variation: new insights in genome diversity.
Genome research 2006;16(8):949-61.
2006: Masayo Sakaki-Yumoto; Chiyoko Kobayashi; Akira Sato; Sayoko Fujimura; Yuko Matsumoto; Minoru Takasato; Tatsuhiko Kodama; Hiroyuki Aburatani; Makoto Asashima; Nobuaki Yoshida; Ryuichi Nishinakamura
The murine homolog of SALL4, a causative gene in Okihiro syndrome, is essential for embryonic stem cell proliferation, and cooperates with Sall1 in anorectal, heart, brain and kidney development.
Development (Cambridge, England) 2006;133(15):3005-13.
2006: Miho Kawamura-Saito; Yukari Yamazaki; Keiko Kaneko; Noriyoshi Kawaguchi; Hiroaki Kanda; Hiroyuki Mukai; Takahiro Gotoh; Tohru Motoi; Masashi Fukayama; Hiroyuki Aburatani; Toichiro Takizawa; Takuro Nakamura
Fusion between CIC and DUX4 up-regulates PEA3 family genes in Ewing-like sarcomas with t(4;19)(q35;q13) translocation.
Human molecular genetics 2006;15(13):2125-37.
2006: Hirotaka Ito; Shin-ichi Funahashi; Naoko Yamauchi; Junji Shibahara; Yutaka Midorikawa; Shigeto Kawai; Yasuko Kinoshita; Akira Watanabe; Yoshitaka Hippo; Toshihiko Ohtomo; Hiroko Iwanari; Atsushi Nakajima; Makuuchi Masatoshi; Masashi Fukayama; Yuichi Hirata; Takao Hamakubo; Tatsuhiko Kodama; Masayuki Tsuchiya; Hiroyuki Aburatani
Identification of ROBO1 as a novel hepatocellular carcinoma antigen and a potential therapeutic and diagnostic target.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(11 Pt 1):3257-64.
2006: Takahiro Yamada; Hisamitsu Ishihara; Akira Tamura; Rui Takahashi; Suguru Yamaguchi; Daisuke Takei; Ai Tokita; Chihiro Satake; Fumi Tashiro; Hideki Katagiri; Hiroyuki Aburatani; Jun-ichi Miyazaki; Yoshitomo Oka
WFS1-deficiency increases endoplasmic reticulum stress, impairs cell cycle progression and triggers the apoptotic pathway specifically in pancreatic beta-cells.
Human molecular genetics 2006;15(10):1600-9.
2006: H J Liu; Yoichi Moroi; Teiichi Masuda; Shinichiro Yasumoto; Hisashi Kokuba; Shinichi Imafuku; Tetsuya Koga; T Tetsuya; Ya-ting Tu; Hiroyuki Aburatani; masutaka furue; Kazunori Urabe
Expression of phosphorylated Stat3, cyclin D1 and Bcl-xL in extramammary Paget disease.
The British journal of dermatology 2006;154(5):926-32.
2006: Yasufumi Goto; Yuriko Matsuzaki; Sachiko Kurihara; Ayako Shimizu; Tsutomu Okada; Kazuhiko Yamamoto; Hiroshi Murata; Minoru Takata; Hiroyuki Aburatani; Dave S B Hoon; Toshiaki Saida; Yutaka Kawakami
A new melanoma antigen fatty acid-binding protein 7, involved in proliferation and invasion, is a potential target for immunotherapy and molecular target therapy.
Cancer research 2006;66(8):4443-9.
2006: Yoji Yamamoto; Akihiko Uehara; Akira Watanabe; Hiroyuki Aburatani; Makoto Komiyama
Chemical-reaction-based site-selective DNA cutter for PCR-free gene manipulation.
Chembiochem : a European journal of chemical biology 2006;7(4):673-7.
2006: Toshiaki Tanaka; Shuying Jiang; H Hotta; K Takano; Hiroko Iwanari; Koichi Sumi; Kenji Daigo; Riuko Ohashi; M Sugai; C Ikegame; H Umezu; Y Hirayama; Yutaka Midorikawa; Yoshitaka Hippo; Akira Watanabe; Yasutoshi Uchiyama; Go Hasegawa; Pc Reid; Hiroyuki Aburatani; Takao Hamakubo; Juro Sakai; Makoto Naito; Tatsuhiko Kodama
Dysregulated expression of P1 and P2 promoter-driven hepatocyte nuclear factor-4alpha in the pathogenesis of human cancer.
The Journal of pathology 2006;208(5):662-72.
2006: Tetsuya Yamada; Hideki Katagiri; Yasushi Ishigaki; Takehide Ogihara; Junta Imai; Kenji Uno; Yutaka Hasegawa; Junhong Gao; Hisamitsu Ishihara; Akira Niijima; Hiroyuki Mano; Hiroyuki Aburatani; Tomoichiro Asano; Yoshitomo Oka
Signals from intra-abdominal fat modulate insulin and leptin sensitivity through different mechanisms: neuronal involvement in food-intake regulation.
Cell metabolism 2006;3(3):223-9.
2006: Yongxin Chen; Yingqiu Guo; Xijin Ge; Hirotaka Itoh; Akira Watanabe; Takeshi Fujiwara; Tatsuhiko Kodama; Hiroyuki Aburatani
Elevated expression and potential roles of human Sp5, a member of Sp transcription factor family, in human cancers.
Biochemical and biophysical research communications 2006;340(3):758-66.
2006: Hideaki Nakajima; Fumi Shibata; Yoshinosuke Fukuchi; Yuko Goto-Koshino; Miyuki Ito; Atsushi Urano; Tatsutoshi Nakahata; Hiroyuki Aburatani; Toshio Kitamura
Immune suppressor factor confers stromal cell line with enhanced supporting activity for hematopoietic stem cells.
Biochemical and biophysical research communications 2006;340(1):35-42.
2006: Kimihiro Yamashita; Hisaki Igarashi; Yasuhiko Kitayama; Takachika Ozawa; Shinichiro Kiyose; Hiroyuki Konno; Teruhisa Kazui; Shumpei Ishikawa; Hiroyuki Aburatani; Fumihiko Tanioka; Masaya Suzuki; Haruhiko Sugimura
Chromosomal numerical abnormality profiles of gastrointestinal stromal tumors.
Japanese journal of clinical oncology 2006;36(2):85-92.
2006: Shintaro Yamazaki; Kenji Miki; Tadatoshi Takayama; Kiyoshi Hasegawa; Masataka Sata; Yutaka Midorikawa; Hiroyuki Aburatani; Makuuchi Masatoshi
Hepatic gene induction in murine bone marrow after hepatectomy.
Journal of hepatology 2006;44(2):325-33.
2006: Kazuhisa Takeda; Satoru Yokoyama; Hiroyuki Aburatani; Takayuki Masuda; Feng Han; Miki Yoshizawa; Naomi Yamaki; Hiroaki Yamamoto; Naomi Eguchi; Yoshihiro Urade; Shigeki Shibahara
Lipocalin-type prostaglandin D synthase as a melanocyte marker regulated by MITF.
Biochemical and biophysical research communications 2006;339(4):1098-106.
2006: Hiromi Okawa; Hozumi Motohashi; Akira Kobayashi; Hiroyuki Aburatani; Thomas W Kensler; Masayuki Yamamoto
Hepatocyte-specific deletion of the keap1 gene activates Nrf2 and confers potent resistance against acute drug toxicity.
Biochemical and biophysical research communications 2006;339(1):79-88.
2006: Yuki Katou; Kiyofumi Kaneshiro; Hiroyuki Aburatani; Katsuhiko Shirahige
Genomic approach for the understanding of dynamic aspect of chromosome behavior.
Methods in enzymology 2006;409():389-410.
2006: Daisuke Komura; Kunihiro Nishimura; Shumpei Ishikawa; Binaya Panda; Jing Huang; Hiroshi Nakamura; Sayoko Ihara; Michitaka Hirose; Keith W Jones; Hiroyuki Aburatani
Noise reduction from genotyping microarrays using probe level information.
In silico biology 2006;6(1-2):79-92.
2006: Jing Huang; Wen Wei; Joyce Chen; Jane Zhang; Guoying Liu; Xiaojun Di; Rui Mei; Shumpei Ishikawa; Hiroyuki Aburatani; Keith W Jones; Michael H Shapero
CARAT: a novel method for allelic detection of DNA copy number changes using high density oligonucleotide arrays.
BMC bioinformatics 2006;7():83.
2006: Amit Aggarwal; Dong Li Guo; Yujin Hoshida; Siu Tsan Yuen; Kent-Man Chu; Samuel So; Alex Boussioutas; Xin Chen; David D L Bowtell; Hiroyuki Aburatani; Suet Yi Leung; Patrick Tan
Topological and functional discovery in a gene coexpression meta-network of gastric cancer.
Cancer research 2006;66(1):232-41.
2006: Takuro Sasayama; Mayu Kato; Hiroyuki Aburatani; Akinori Kuzuya; Makoto Komiyama
Simultaneous genotyping of indels and SNPs by mass spectroscopy.
Journal of the American Society for Mass Spectrometry 2006;17(1):3-8.
2005: Ryuichi Mashima; Kazuko Saeki; Daisuke Aki; Yasumasa Minoda; Hiromi Takaki; Takahito Sanada; Takashi Kobayashi; Hiroyuki Aburatani; Yuji Yamanashi; Akihiko Yoshimura
FLN29, a novel interferon- and LPS-inducible gene acting as a negative regulator of toll-like receptor signaling.
The Journal of biological chemistry 2005;280(50):41289-97.
2005: Hiroyuki Aburatani
[Functional genomic analysis with microarray technology].
Nihon rinsho. Japanese journal of clinical medicine 2005;63 Suppl 12():171-5.
2005: Daisuke Matsubara; Toshiro Niki; Shumpei Ishikawa; Akiteru Goto; Etsuko Ohara; Takehiko Yokomizo; Claus W Heizmann; Hiroyuki Aburatani; Sachiko Moriyama; Hirokazu Moriyama; Yoshihiro Nishimura; Nobuaki Funata; Masashi Fukayama
Differential expression of S100A2 and S100A4 in lung adenocarcinomas: clinicopathological significance, relationship to p53 and identification of their target genes.
Cancer science 2005;96(12):844-57.
2005: Naoko Yamauchi; Akira Watanabe; Michiyo Hishinuma; Ken-Ichi Ohashi; Yutaka Midorikawa; Yasuyuki Morishita; Toshiro Niki; Junji Shibahara; Masaya Mori; Makuuchi Masatoshi; Yoshitaka Hippo; Tatsuhiko Kodama; Hiroko Iwanari; Hiroyuki Aburatani; Masashi Fukayama
The glypican 3 oncofetal protein is a promising diagnostic marker for hepatocellular carcinoma.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2005;18(12):1591-8.
2005: Tomoiki Aiba; Kazuyoshi Kohu; Takefumi Ishidao; Naomi Yasui; Akira Horii; Hiroyuki Aburatani; Tetsu Akiyama
The mammalian homolog of the Drosophila discs large tumor suppressor protein up-regulates expression of the ELR+ CXC chemokine Scyb5.
Biochemical and biophysical research communications 2005;337(1):191-4.
2005: Masafumi Tauchi; Azumi Hida; Takaaki Negishi; Fumiki Katsuoka; Shuhei Noda; Junsei Mimura; Tomonori Hosoya; Akinori Yanaka; Hiroyuki Aburatani; Yoshiaki Fujii-Kuriyama; Hozumi Motohashi; Masayuki Yamamoto
Constitutive expression of aryl hydrocarbon receptor in keratinocytes causes inflammatory skin lesions.
Molecular and cellular biology 2005;25(21):9360-8.
2005: Kentaro Inamura; Takeshi Fujiwara; Yujin Hoshida; Takayuki Isagawa; Michael Jones; Carl Virtanen; Miyuki Shimane; Yukitoshi Satoh; Sakae Okumura; Ken Nakagawa; Eiju Tsuchiya; Shumpei Ishikawa; Hiroyuki Aburatani; Hitoshi Nomura; Yuichi Ishikawa
Two subclasses of lung squamous cell carcinoma with different gene expression profiles and prognosis identified by hierarchical clustering and non-negative matrix factorization.
Oncogene 2005;24(47):7105-13.
2005: Akinori Hishiya; Masako Ito; Hiroyuki Aburatani; Noboru Motoyama; Kyoji Ikeda; Ken Watanabe
Ataxia telangiectasia mutated (Atm) knockout mice as a model of osteopenia due to impaired bone formation.
Bone 2005;37(4):497-503.
2005: Fumiki Katsuoka; Hozumi Motohashi; Tetsuro Ishii; Hiroyuki Aburatani; James Douglas Engel; Masayuki Yamamoto
Genetic evidence that small maf proteins are essential for the activation of antioxidant response element-dependent genes.
Molecular and cellular biology 2005;25(18):8044-51.
2005: Atsushi B Tsuji; Aya Sugyo; Toshiaki Ogiu; Masashi Sagara; Tomo Kimura; Atsuko Ishikawa; Hitomi Sudo; Marika Ohtsuki; Hiroyuki Aburatani; Takashi Imai; Yoshi-Nobu Harada
Fine mapping of radiation susceptibility and gene expression analysis of LEC congenic rat lines.
Genomics 2005;86(3):271-9.
2005: Masatomo Yanagihara; Susumu Ishikawa; Masanori Naito; Junta Nakajima; Hiroyuki Aburatani; Masanori Hatakeyama
Paired-like homeoprotein ESXR1 acts as a sequence-specific transcriptional repressor of the human K-ras gene.
Oncogene 2005;24(38):5878-87.
2005: Seiji Yamashita; Yoshimasa Tanaka; Shuichi Tsutsumi; Hiroyuki Aburatani; Nagahiro Minato; Sayoko Ihara
Analysis of mechanism for human gammadelta T cell recognition of nonpeptide antigens.
Biochemical and biophysical research communications 2005;334(2):349-60.
2005: Shumpei Ishikawa; Daisuke Komura; Shingo Tsuji; Kunihiro Nishimura; Shogo Yamamoto; Binaya Panda; Jing Huang; Masashi Fukayama; Keith W Jones; Hiroyuki Aburatani
Allelic dosage analysis with genotyping microarrays.
Biochemical and biophysical research communications 2005;333(4):1309-14.
2005: Xijin Ge; Shogo Yamamoto; Shuichi Tsutsumi; Yutaka Midorikawa; Sayoko Ihara; San Ming Wang; Hiroyuki Aburatani
Interpreting expression profiles of cancers by genome-wide survey of breadth of expression in normal tissues.
Genomics 2005;86(2):127-41.
2005: Atsuhiko T Naito; Hiroshi Akazawa; Hiroyuki Takano; Tohru Minamino; Toshio Nagai; Hiroyuki Aburatani; Issei Komuro
Phosphatidylinositol 3-kinase-Akt pathway plays a critical role in early cardiomyogenesis by regulating canonical Wnt signaling.
Circulation research 2005;97(2):144-51.
2005: Kazuyuki Yokoyama; Hideaki Higashi; Susumu Ishikawa; Yumiko Fujii; Satoshi Kondo; Hiroyuki Kato; Takeshi Azuma; Akihiro Wada; Toshiya Hirayama; Hiroyuki Aburatani; Masanori Hatakeyama
Functional antagonism between Helicobacter pylori CagA and vacuolating toxin VacA in control of the NFAT signaling pathway in gastric epithelial cells.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(27):9661-6.
2005: Takahiro Shimamura; Hirotaka Ito; Junji Shibahara; Akira Watanabe; Yoshitaka Hippo; Hirokazu Taniguchi; Yongxin Chen; Takeshi Kashima; Toshihiko Ohtomo; Fumihiko Tanioka; Hiroko Iwanari; Tatsuhiko Kodama; Teruhisa Kazui; Haruhiko Sugimura; Masashi Fukayama; Hiroyuki Aburatani
Overexpression of MUC13 is associated with intestinal-type gastric cancer.
Cancer science 2005;96(5):265-73.
2005: Makoto Kano; Shuichi Tsutsumi; Nobutaka Kawahara; Yan Wang; Akitake Mukasa; Takaaki Kirino; Hiroyuki Aburatani
A meta-clustering analysis indicates distinct pattern alteration between two series of gene expression profiles for induced ischemic tolerance in rats.
Physiological genomics 2005;21(2):274-83.
2005: Toshikatsu Hanada; Kentaro Tanaka; Yumiko Matsumura; Moriyasu Yamauchi; Hitomi Nishinakamura; Hiroyuki Aburatani; Ryuichi Mashima; Masato Kubo; Takashi Kobayashi; Akihiko Yoshimura
Induction of hyper Th1 cell-type immune responses by dendritic cells lacking the suppressor of cytokine signaling-1 gene.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(7):4325-32.
2005: Takashi Inozume; Yuriko Matsuzaki; Sachiko Kurihara; Tomonobu Fujita; Akifumi Yamamoto; Hiroyuki Aburatani; Shinji Shimada; Yutaka Kawakami
Novel melanoma antigen, FCRL/FREB, identified by cDNA profile comparison using DNA chip are immunogenic in multiple melanoma patients.
International journal of cancer. Journal international du cancer 2005;114(2):283-90.
2005: Hiroyuki Aburatani
Discovery of a new biomarker for gastroenterological cancers.
Journal of gastroenterology 2005;40 Suppl 16():1-6.
2005: H-J Liu; S Moroi; Shinichiro Yasumoto; Tetsuya Koga; Teiichi Masuda; Q-J Chen; Ya-ting Tu; M Fure; Hiroyuki Aburatani; Kazunori Urabe
Expression of elafin in extramammary Paget's disease.
The British journal of dermatology 2005;152(3):578-9.
2005: Hiroyuki Aburatani
[Genetic testing].
Nihon rinsho. Japanese journal of clinical medicine 2005;63(3):375-82.
2005: Shin-ichi Fukumoto; Naoko Yamauchi; Hisashi Moriguchi; Yoshitaka Hippo; Akira Watanabe; Junji Shibahara; Hirokazu Taniguchi; Shumpei Ishikawa; Hirotaka Ito; Shogo Yamamoto; Hiroko Iwanari; Mitsugu Hironaka; Yuichi Ishikawa; Toshiro Niki; Yasunori Sohara; Tatsuhiko Kodama; Masaharu Nishimura; Masashi Fukayama; Hirotoshi Dosaka-Akita; Hiroyuki Aburatani
Overexpression of the aldo-keto reductase family protein AKR1B10 is highly correlated with smokers' non-small cell lung carcinomas.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(5):1776-85.
2005: Daisuke Komura; Hiroshi Nakamura; S Tsutsumi; Hiroyuki Aburatani; Sayoko Ihara
Multidimensional support vector machines for visualization of gene expression data.
Bioinformatics (Oxford, England) 2005;21(4):439-44.
2005: Akihiko Uehara; Yoji Yamamoto; Akira Watanabe; Hiroyuki Aburatani; Makoto Komiyama
Construction of chimera protein by using artificial restriction DNA cutter.
Nucleic acids symposium series (2004) 2005;(49):279-80.
2005: Yoji Yamamoto; Jing-Min Zhou; Takafumi Tomita; Akihiko Uehara; Yuichiro Aiba; Akira Watanabe; Hiroyuki Aburatani; Makoto Komiyama
Gene manipulation using artificial restriction DNA cutter.
Nucleic acids symposium series (2004) 2005;(49):73-4.
2004: Takashi Minami; Keiko Horiuchi; Mai Miura; Md Ruhul Abid; Wakako Takabe; Noriko Noguchi; Kohro Takahide; Xijin Ge; Hiroyuki Aburatani; Takao Hamakubo; Tatsuhiko Kodama; William C Aird
Vascular endothelial growth factor- and thrombin-induced termination factor, Down syndrome critical region-1, attenuates endothelial cell proliferation and angiogenesis.
The Journal of biological chemistry 2004;279(48):50537-54.
2004: Yutaka Midorikawa; Shuichi Tsutsumi; Kunihiro Nishimura; Naoko Kamimura; Makoto Kano; Hirohiko Sakamoto; Makuuchi Masatoshi; Hiroyuki Aburatani
Distinct chromosomal bias of gene expression signatures in the progression of hepatocellular carcinoma.
Cancer research 2004;64(20):7263-70.
2004: Yasutomi Kamei; Shinji Miura; Miki Suzuki; Yuko Kai; Junko Mizukami; Tomoyasu Taniguchi; Keiji Mochida; Tomoko Hata; Junichiro Matsuda; Hiroyuki Aburatani; Ichizo Nishino; Osamu Ezaki
Skeletal muscle FOXO1 (FKHR) transgenic mice have less skeletal muscle mass, down-regulated Type I (slow twitch/red muscle) fiber genes, and impaired glycemic control.
The Journal of biological chemistry 2004;279(39):41114-23.
2004: Hirotaka Miyachi; Kazunori Ikebukuro; Kazuyoshi Yano; Hiroyuki Aburatani; Isao Karube
Single nucleotide polymorphism typing on DNA array with hydrophobic surface fabricated by plasma-polymerization technique.
Biosensors & bioelectronics 2004;20(2):184-9.
2004: Hiroyuki Aburatani
[Functional genomics analysis on DNA microarray].
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 2004;49(11 Suppl):1853-8.
2004: Kyoko Fujiwara; Masako Ochiai; Tsutomu Ohta; Misao Ohki; Hiroyuki Aburatani; Minako Nagao; Takashi Sugimura; Hitoshi Nakagama
Global gene expression analysis of rat colon cancers induced by a food-borne carcinogen, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine.
Carcinogenesis 2004;25(8):1495-505.
2004: Tokumitsu Watanabe; Masahiro Akishita; Takashi Nakaoka; Hong He; Yukiko Miyahara; Naohide Yamashita; Youichiro Wada; Hiroyuki Aburatani; Masao Yoshizumi; Koichi Kozaki; Yasuyoshi Ouchi
Caveolin-1, Id3a and two LIM protein genes are upregulated by estrogen in vascular smooth muscle cells.
Life sciences 2004;75(10):1219-29.
2004: Koichi Matsuo; Deborah L Galson; Chen Zhao; Lan Peng; Catherine Laplace; Kent Z Q Wang; Marcus A Bachler; Hitoshi Amano; Hiroyuki Aburatani; Hiromichi Ishikawa; Erwin F Wagner
Nuclear factor of activated T-cells (NFAT) rescues osteoclastogenesis in precursors lacking c-Fos.
The Journal of biological chemistry 2004;279(25):26475-80.
2004: Minoru Takasato; Kenji Osafune; Yuko Matsumoto; Yuki Kataoka; Nobuaki Yoshida; Hiroko Meguro; Hiroyuki Aburatani; Makoto Asashima; Ryuichi Nishinakamura
Identification of kidney mesenchymal genes by a combination of microarray analysis and Sall1-GFP knockin mice.
Mechanisms of development 2004;121(6):547-57.
2004: Junko Takita; Masami Ishii; Shuichi Tsutsumi; Yukichi Tanaka; Keisuke Kato; Yasunori Toyoda; Ryoji Hanada; Keiko Yamamoto; Yasuhide Hayashi; Hiroyuki Aburatani
Gene expression profiling and identification of novel prognostic marker genes in neuroblastoma.
Genes, chromosomes & cancer 2004;40(2):120-32.
2004: Toshio Ogihara; Tomoichiro Asano; Hideki Katagiri; Hideyuki Sakoda; Motonobu Anai; Nobuhiro Shojima; Hiraku Ono; Midori Fujishiro; Akifumi Kushiyama; Yasushi Fukushima; Masatoshi Kikuchi; Noriko Noguchi; Hiroyuki Aburatani; Yukiko Gotoh; Issei Komuro; Toshiro Fujita
Oxidative stress induces insulin resistance by activating the nuclear factor-kappa B pathway and disrupting normal subcellular distribution of phosphatidylinositol 3-kinase.
Diabetologia 2004;47(5):794-805.
2004: Yoshitaka Hippo; Kiyotaka Watanabe; Akira Watanabe; Yutaka Midorikawa; Shogo Yamamoto; Sayoko Ihara; Susumu Tokita; Hiroko Iwanari; Yukio Ito; Kiyotaka Nakano; Jun-ichi Nezu; Hiroyuki Tsunoda; Takeshi Yoshino; Iwao Ohizumi; Masayuki Tsuchiya; Shin Ohnishi; Makuuchi Masatoshi; Takao Hamakubo; Tatsuhiko Kodama; Hiroyuki Aburatani
Identification of soluble NH2-terminal fragment of glypican-3 as a serological marker for early-stage hepatocellular carcinoma.
Cancer research 2004;64(7):2418-23.
2004: Nobutaka Kawahara; Yan Wang; Akitake Mukasa; Kazuhide Furuya; Tatsuya Shimizu; Takao Hamakubo; Hiroyuki Aburatani; Tatsuhiko Kodama; Takaaki Kirino
Genome-wide gene expression analysis for induced ischemic tolerance and delayed neuronal death following transient global ischemia in rats.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2004;24(2):212-23.
2004: Akiko Joo; Hiroyuki Aburatani; Eiichi Morii; Hideo Iba; Akihiko Yoshimura
STAT3 and MITF cooperatively induce cellular transformation through upregulation of c-fos expression.
Oncogene 2004;23(3):726-34.
2004: Kohro Takahide; Toshiya Tanaka; Takeshi Murakami; Yoichiro Wada; Hiroyuki Aburatani; Takao Hamakubo; Tatsuhiko Kodama
A comparison of differences in the gene expression profiles of phorbol 12-myristate 13-acetate differentiated THP-1 cells and human monocyte-derived macrophage.
Journal of atherosclerosis and thrombosis 2004;11(2):88-97.
2004: Akitake Mukasa; Keisuke Ueki; Xijin Ge; Shumpei Ishikawa; Takafumi Ide; Takamitsu Fujimaki; Ryo Nishikawa; Akio Asai; Takaaki Kirino; Hiroyuki Aburatani
Selective expression of a subset of neuronal genes in oligodendroglioma with chromosome 1p loss.
Brain pathology (Zurich, Switzerland) 2004;14(1):34-42.
2003: Akira Watanabe; Yoshitaka Hippo; Hirokazu Taniguchi; Hiroko Iwanari; Masakazu Yashiro; Kosei Hirakawa; Tatsuhiko Kodama; Hiroyuki Aburatani
An opposing view on WWOX protein function as a tumor suppressor.
Cancer research 2003;63(24):8629-33.
2003: Miho Mizukami; Hiroshi Hasegawa; Kohro Takahide; Haruhiro Toko; Sumiyo Kudoh; Yunzeng Zou; Hiroyuki Aburatani; Issei Komuro
Gene expression profile revealed different effects of angiotensin II receptor blockade and angiotensin-converting enzyme inhibitor on heart failure.
Journal of cardiovascular pharmacology 2003;42 Suppl 1():S1-6.
2003: Shigeo Matsuyama; Manabu Iwadate; Miki Kondo; Masao Saitoh; Aki Hanyu; Kiyoshi Shimizu; Hiroyuki Aburatani; Hiromu K Mishima; Takeshi Imamura; Kohei Miyazono; Keiji Miyazawa
SB-431542 and Gleevec inhibit transforming growth factor-beta-induced proliferation of human osteosarcoma cells.
Cancer research 2003;63(22):7791-8.
2003: Yuichi Matsui; Akio Saiura; Yasuhiko Sugawara; Masataka Sata; Katsutoshi Naruse; Hideo Yagita; Kohro Takahide; Chikage Mataki; Akashi Izumi; Takuhiro Yamaguchi; Takashi Minami; Toshiko Sakihama; Sayoko Ihara; Hiroyuki Aburatani; Takao Hamakubo; Tatsuhiko Kodama; Makuuchi Masatoshi
Identification of gene expression profile in tolerizing murine cardiac allograft by costimulatory blockade.
Physiological genomics 2003;15(3):199-208.
2003: Daisuke Sugiyama; Hiroyuki Kusuhara; Hirokazu Taniguchi; Shumpei Ishikawa; Yoshitane Nozaki; Hiroyuki Aburatani; Yuichi Sugiyama
Functional characterization of rat brain-specific organic anion transporter (Oatp14) at the blood-brain barrier: high affinity transporter for thyroxine.
The Journal of biological chemistry 2003;278(44):43489-95.
2003: Ei Sekoguchi; Norihiro Sato; Akihiro Yasui; Shinji Fukada; Yuji Nimura; Hiroyuki Aburatani; Kyoji Ikeda; Akira Matsuura
A novel mitochondrial carnitine-acylcarnitine translocase induced by partial hepatectomy and fasting.
The Journal of biological chemistry 2003;278(40):38796-802.
2003: Shuichi Tsutsumi; Takeshi Taketani; Kunihiro Nishimura; Xijin Ge; Tomohiko Taki; Kanji Sugita; Eiichi Ishii; Ryoji Hanada; Misao Ohki; Hiroyuki Aburatani; Yasuhide Hayashi
Two distinct gene expression signatures in pediatric acute lymphoblastic leukemia with MLL rearrangements.
Cancer research 2003;63(16):4882-7.
2003: Ryoichi Ono; Hirosuke Shiura; Hiroyuki Aburatani; Takashi Kohda; Tomoko Kaneko-Ishino; Fumitoshi Ishino
Identification of a large novel imprinted gene cluster on mouse proximal chromosome 6.
Genome research 2003;13(7):1696-705.
2003: Takumi Satoh; Megumi Baba; Daisaku Nakatsuka; Yasuyuki Ishikawa; Hiroyuki Aburatani; Kyoji Furuta; Toshihisa Ishikawa; Hiroshi Hatanaka; Masaaki Suzuki; Yasuyoshi Watanabe
Role of heme oxygenase-1 protein in the neuroprotective effects of cyclopentenone prostaglandin derivatives under oxidative stress.
The European journal of neuroscience 2003;17(11):2249-55.
2003: Hiroyuki Aburatani; Tatsuhiko Kodama
[Laboratory for systems biology and medicine at RCAST, University of Tokyo].
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 2003;48(7):833-5.
2003: Hidetada Shimizu; Hirokazu Taniguchi; Yoshitaka Hippo; Yoshihide Hayashizaki; Hiroyuki Aburatani; Toshihisa Ishikawa
Characterization of the mouse Abcc12 gene and its transcript encoding an ATP-binding cassette transporter, an orthologue of human ABCC12.
Gene 2003;310():17-28.
2003: Makoto Komiyama; Sheng Ye; Xingguo Liang; Yoji Yamamoto; Takafumi Tomita; Jing-Min Zhou; Hiroyuki Aburatani
PNA for one-base differentiating protection of DNA from nuclease and its use for SNPs detection.
Journal of the American Chemical Society 2003;125(13):3758-62.
2003: Yoko Fujiwara; Masayo Yokoyama; Rumi Sawada; Yousuke Seyama; Masami Ishii; Shunichi Tsutsumi; Hiroyuki Aburatani; Satoko Hanaka; Hiroshige Itakura; Akiyo Matsumoto
Analysis of the comprehensive effects of polyunsaturated fatty acid on mRNA expression using a gene chip.
Journal of nutritional science and vitaminology 2003;49(2):125-32.
2003: Takeshi Kashima; Kazuya Nakamura; Jitsutaro Kawaguchi; Masakatsu Takanashi; Tsuyoshi Ishida; Hiroyuki Aburatani; Akira Kudo; Masashi Fukayama; Agamemnon E Grigoriadis
Overexpression of cadherins suppresses pulmonary metastasis of osteosarcoma in vivo.
International journal of cancer. Journal international du cancer 2003;104(2):147-54.
2003: Makoto Kano; Kunihiro Nishimura; Shumpei Ishikawa; Shuichi Tsutsumi; Koichi Hirota; Michitaka Hirose; Hiroyuki Aburatani
Expression imbalance map: a new visualization method for detection of mRNA expression imbalance regions.
Physiological genomics 2003;13(1):31-46.
2003: Yutaka Midorikawa; Shumpei Ishikawa; Hiroko Iwanari; Takeshi Imamura; Hirohiko Sakamoto; Kohei Miyazono; Tatsuhiko Kodama; Makuuchi Masatoshi; Hiroyuki Aburatani
Glypican-3, overexpressed in hepatocellular carcinoma, modulates FGF2 and BMP-7 signaling.
International journal of cancer. Journal international du cancer 2003;103(4):455-65.
2003: Xijin Ge; Shuichi Tsutsumi; Hiroyuki Aburatani; Shuichi Iwata
Reducing false positives in molecular pattern recognition.
Genome informatics. International Conference on Genome Informatics 2003;14():34-43.
2003: Sheng Ye; Xingguo Liang; Yoji Yamamoto; Jing-Min Zhou; Takafumi Tomita; Hiroyuki Aburatani; Makoto Komiyama
Simultaneous detection of multiple single nucleotide polymorphism by single-strand-specific nuclease and PNA probe.
Nucleic acids research. Supplement (2001) 2003;(3):185-6.
2003: Ja-Mun Chong; Kazuya Sakuma; Makoto Sudo; Tetsuo Ushiku; Hiroshi Uozaki; Junji Shibahara; Hideo Nagai; Nobuaki Funata; Hirokazu Taniguchi; Hiroyuki Aburatani; Masashi Fukayama
Global and non-random CpG-island methylation in gastric carcinoma associated with Epstein-Barr virus.
Cancer science 2003;94(1):76-80.
2002: Hikaru Yabuuchi; Shin ichiro Takayanagi; Keigo Yoshinaga; Naoyuki Taniguchi; Hiroyuki Aburatani; Toshihisa Ishikawa
ABCC13, an unusual truncated ABC transporter, is highly expressed in fetal human liver.
Biochemical and biophysical research communications 2002;299(3):410-7.
2002: Takehide Ogihara; Tomoichiro Asano; Katsuyuki Ando; Yuko Chiba; Hideyuki Sakoda; Motonobu Anai; Nobuhiro Shojima; Hiraku Ono; Yukiko Onishi; Midori Fujishiro; Hideki Katagiri; Yasushi Fukushima; Masatoshi Kikuchi; Noriko Noguchi; Hiroyuki Aburatani; Issei Komuro; Toshiro Fujita
Angiotensin II-induced insulin resistance is associated with enhanced insulin signaling.
Hypertension 2002;40(6):872-9.
2002: Tatsuru Ota; Makiko Fujii; Takashi Sugizaki; Masami Ishii; Keiji Miyazawa; Hiroyuki Aburatani; Kohei Miyazono
Targets of transcriptional regulation by two distinct type I receptors for transforming growth factor-beta in human umbilical vein endothelial cells.
Journal of cellular physiology 2002;193(3):299-318.
2002: Atsushi Nakajima; Koichiro Wada; Kazufumi Katayama; Lawrence J Saubermann; Emi Osawa; Hajime Nagase; Norio Ueno; Nobuyuki Matsuhashi; Hiroyuki Aburatani
Gene expression profile after peroxisome proliferator activator receptor-gamma ligand administration in dextran sodium sulfate mice.
Journal of gastroenterology 2002;37 Suppl 14():62-6.
2002: Lawrence J Saubermann; Atsushi Nakajima; Koichiro Wada; Shuping Zhao; Yasuo Terauchi; Takashi Kadowaki; Hiroyuki Aburatani; Nobuyuki Matsuhashi; Ryozo Nagai; Richard S Blumberg
Peroxisome proliferator-activated receptor gamma agonist ligands stimulate a Th2 cytokine response and prevent acute colitis.
Inflammatory bowel diseases 2002;8(5):330-9.
2002: Ja-Mun Chong; Kazuya Sakuma; Makoto Sudo; Toshio Osawa; Etsuko Ohara; Hiroshi Uozaki; Junji Shibahara; Kenji Kuroiwa; Shin-Ichi Tominaga; Yoshitaka Hippo; Hiroyuki Aburatani; Nobuaki Funata; Masashi Fukayama
Interleukin-1beta expression in human gastric carcinoma with Epstein-Barr virus infection.
Journal of virology 2002;76(13):6825-31.
2002: Akitake Mukasa; Keisuke Ueki; Shinichi Matsumoto; Shuichi Tsutsumi; Ryo Nishikawa; Takamitsu Fujimaki; Akio Asai; Takaaki Kirino; Hiroyuki Aburatani
Distinction in gene expression profiles of oligodendrogliomas with and without allelic loss of 1p.
Oncogene 2002;21(25):3961-8.
2002: Yutaka Midorikawa; Shuichi Tsutsumi; Hirokazu Taniguchi; Masami Ishii; Yuko Kobune; Tatsuhiko Kodama; Makuuchi Masatoshi; Hiroyuki Aburatani
Identification of genes associated with dedifferentiation of hepatocellular carcinoma with expression profiling analysis.
Japanese journal of cancer research : Gann 2002;93(6):636-43.
2002: Akio Saiura; Kohro Takahide; Takashi Yamamoto; Akashi Izumi; Yoichiro Wada; Hiroyuki Aburatani; Yasuhiko Sugawara; Takao Hamakubo; Tadatsugu Taniguchi; Makoto Naito; Tatsuhiko Kodama; Makuuchi Masatoshi
Detection of an up-regulation of a group of chemokine genes in murine cardiac allograft in the absence of interferon-gamma by means of DNA microarray.
Transplantation 2002;73(9):1480-6.
2002: Mayumi Takahashi; Nobuyo Tsuboyama-Kasaoka; Teruyo Nakatani; Masami Ishii; Shuichi Tsutsumi; Hiroyuki Aburatani; Osamu Ezaki
Fish oil feeding alters liver gene expressions to defend against PPARalpha activation and ROS production.
American journal of physiology. Gastrointestinal and liver physiology 2002;282(2):G338-48.
2002: Akihiro Higuchi; Shigeto Shimmura; Masami Ishii; Hiroyuki Aburatani; Kazuo Tsubota
Serum- and serum deprivation-induced transcriptional profiles of cultured conjunctival epithelial cells.
Advances in experimental medicine and biology 2002;506(Pt A):673-6.
2002: Yoko Fujiwara; Masayo Yokoyama; Rumi Umeda-Sawada; Yousuke Seyama; Masami Ishii; Shunichi Tsutsumi; Hiroyuki Aburatani; Satoko Hanaka; Hiroshige Itakura; Akiyo Matsumoto
Influence of polyunsaturated fatty acid on gene expression in HepG2 cells.
Journal of atherosclerosis and thrombosis 2002;9(3):157-62.
2002: Yoshitaka Hippo; Hirokazu Taniguchi; Shuichi Tsutsumi; Naoko Machida; Ja-Mun Chong; Masashi Fukayama; Tatsuhiko Kodama; Hiroyuki Aburatani
Global gene expression analysis of gastric cancer by oligonucleotide microarrays.
Cancer research 2002;62(1):233-40.
2001: Wakako Takabe; Tsunenori Kodama; Takao Hamakubo; Keiichi Tanaka; Takahiro Suzuki; Hiroyuki Aburatani; N Matsukawa; Noriko Noguchi
Anti-atherogenic antioxidants regulate the expression and function of proteasome alpha-type subunits in human endothelial cells.
The Journal of biological chemistry 2001;276(44):40497-501.
2001: Akio Saiura; Chikage Mataki; Takeshi Murakami; Michihisa Umetani; Yoichiro Wada; Kohro Takahide; Hiroyuki Aburatani; Yasushi Harihara; Takao Hamakubo; Takuhiro Yamaguchi; G Hasegawa; Makoto Naito; Makuuchi Masatoshi; Tsunenori Kodama
A comparison of gene expression in murine cardiac allografts and isografts by means DNA microarray analysis.
Transplantation 2001;72(2):320-9.
2001: S Akiyoshi; M Ishii; N Nemoto; M Kawabata; Hiroyuki Aburatani; K Miyazono
Targets of transcriptional regulation by transforming growth factor-beta: expression profile analysis using oligonucleotide arrays.
Japanese journal of cancer research : Gann 2001;92(3):257-68.
2001: Yoshitaka Hippo; Masakazu Yashiro; M Ishii; Hirokazu Taniguchi; Shuichi Tsutsumi; Kosei Hirakawa; Tatsuhiko Kodama; Hiroyuki Aburatani
Differential gene expression profiles of scirrhous gastric cancer cells with high metastatic potential to peritoneum or lymph nodes.
Cancer research 2001;61(3):889-95.
2000: M Ishii; S Hashimoto; Shuichi Tsutsumi; Y Wada; K Matsushima; T Kodama; Hiroyuki Aburatani
Direct comparison of GeneChip and SAGE on the quantitative accuracy in transcript profiling analysis.
Genomics 2000;68(2):136-43.
2000: Yukio Hiroi; R Chen; H Sawa; Toru Hosoda; Sumiyo Kudoh; Y Kobayashi; Hiroyuki Aburatani; K Nagashima; Ryozo Nagai; Yoshio Yazaki; M Edward Medof; Issei Komuro
Cloning of murine glycosyl phosphatidylinositol anchor attachment protein, GPAA1.
American journal of physiology. Cell physiology 2000;279(1):C205-12.
2000: Wakako Takabe; Chikage Mataki; Yoichiro Wada; Masami Ishii; Akashi Izumi; Hiroyuki Aburatani; Takao Hamakubo; Etsuo Niki; Tsunenori Kodama; Noriko Noguchi
Gene expression induced by BO-653, probucol and BHQ in human endothelial cells.
Journal of atherosclerosis and thrombosis 2000;7(4):223-30.
2000: Kohro Takahide; T Nakajima; Yoichiro Wada; Akira Sugiyama; Masami Ishii; Shunichi Tsutsumi; Hiroyuki Aburatani; I Imoto; J Inazawa; Takao Hamakubo; Tsunenori Kodama; Mitsuru Emi
Genomic structure and mapping of human orphan receptor LXR alpha: upregulation of LXRa mRNA during monocyte to macrophage differentiation.
Journal of atherosclerosis and thrombosis 2000;7(3):145-51.
2000: Chikage Mataki; Takeshi Murakami; Michihisa Umetani; Yoichiro Wada; Masami Ishii; Shunichi Tsutsumi; Hiroyuki Aburatani; Takao Hamakubo; Tsunenori Kodama
A novel zinc finger protein mRNA in human umbilical vein endothelial cells is profoundly induced by tumor necrosis factor alpha.
Journal of atherosclerosis and thrombosis 2000;7(2):97-103.
2000: Takeshi Murakami; Chikage Mataki; C Nagao; Michihisa Umetani; Yoichiro Wada; Masami Ishii; Shunichi Tsutsumi; Kohro Takahide; Akio Saiura; Hiroyuki Aburatani; Takao Hamakubo; Tsunenori Kodama
The gene expression profile of human umbilical vein endothelial cells stimulated by tumor necrosis factor alpha using DNA microarray analysis.
Journal of atherosclerosis and thrombosis 2000;7(1):39-44.
1999: Takafumi Ishida; R Takashima; Masashi Fukayama; C Hamada; Yoshitaka Hippo; T Fujii; S Moriyama; C Matsuba; Yutaka Nakahori; H Morita; Y Yazaki; Tatsuhiko Kodama; S Nishimura; Hiroyuki Aburatani
New DNA polymorphisms of human MMH/OGG1 gene: prevalence of one polymorphism among lung-adenocarcinoma patients in Japanese.
International journal of cancer. Journal international du cancer 1999;80(1):18-21.
1999: Takafumi Ishida; Yoshitaka Hippo; Yutaka Nakahori; Ikumi Matsushita; Tatsuhiko Kodama; S Nishimura; Hiroyuki Aburatani
Structure and chromosome location of human OGG1.
Cytogenetics and cell genetics 1999;85(3-4):232-6.
1998: Toshiaki Gunji; Shin Ohnishi; Yoshitaka Hippo; H Miura; Hiroyuki Aburatani; Kuni Ohtomo; K Kitamura; Y Yazaki
[A case of severe drug-induced peliosis hepatis with radiologically confirmed healing].
Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology 1998;95(12):1378-81.
1998: Yukio Hiroi; Issei Komuro; Ikumi Matsushita; Hiroyuki Aburatani; Toru Hosoda; Yutaka Nakahori; M Edward Medof; Yoshio Yazaki
Assignment of the human GPAA1 gene, which encodes a product required for the attachment of glycosylphosphatidylinositols to proteins, at 8q24.
Genomics 1998;54(2):354-5.
1997: Hiroyuki Aburatani; Yoshitaka Hippo; Takafumi Ishida; R Takashima; C Matsuba; Tatsuhiko Kodama; M Takao; A Yasui; Kaneyoshi Yamamoto; M Asano
Cloning and characterization of mammalian 8-hydroxyguanine-specific DNA glycosylase/apurinic, apyrimidinic lyase, a functional mutM homologue.
Cancer research 1997;57(11):2151-6.
1996: Hiroyuki Aburatani
[Positional cloning].
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 1996;41(15 Suppl):2424-32.
1996: Hiroyuki Aburatani
[Representational difference analysis (RDA): finding the genetic lesions in cancer DNA].
Nihon rinsho. Japanese journal of clinical medicine 1996;54(4):949-54.
1996: Hiroyuki Aburatani; T Kodama
[Representational difference analysis: identification of the differences between genomes].
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 1996;41(5):573-9.
1992: S Naganawa; T Kodama; Hiroyuki Aburatani; A Matsumoto; H Itakura; Y Takashima; M Kawamura; Yutaka Muto
Genetic analysis of a Japanese family with normotriglyceridemic abetalipoproteinemia indicates a lack of linkage to the apolipoprotein B gene.
Biochemical and biophysical research communications 1992;182(1):99-104.
1990: A Matsumoto; M Naito; H Itakura; S Ikemoto; H Asaoka; I Hayakawa; H Kanamori; Hiroyuki Aburatani; F Takaku; H Suzuki
Human macrophage scavenger receptors: primary structure, expression, and localization in atherosclerotic lesions.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(23):9133-7.
1990: T Ishikawa; Kazuhiko Umesono; David J Mangelsdorf; Hiroyuki Aburatani; B Z Stanger; Y Shibasaki; M Imawari; Ronald M Evans; F Takaku
A functional retinoic acid receptor encoded by the gene on human chromosome 12.
Molecular endocrinology (Baltimore, Md.) 1990;4(6):837-44.
1989: Hiroyuki Aburatani; A Matsumoto; Takatoshi Ishikawa; F Takaku; H Itakura
Single base substitution between human intestinal and hepatic apolipoprotein B mRNA detected by ribonuclease cleavage analysis.
Journal of biochemistry 1989;105(6):911-5.
1989: Nobuyuki Matsuhashi; S Ohnishi; Hiroyuki Aburatani; K Sugano; M Imawari; F Takaku; F Konishi
[A case of asymptomatic intrahepatic primary sclerosing cholangitis associated with atypical ulcerative colitis].
Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology 1989;86(3):793-7.
1988: Hitoshi Shimano; Hiroyuki Aburatani; N Mori; Shun Ishibashi; T Gotohda; H Mokuno; M Kawakami; Yasuo Akanuma; F Takaku; T Murase
Down-regulation of hepatic LDL receptor protein and messenger RNA in fasted rabbits.
Journal of biochemistry 1988;104(5):712-6.
1988: Hiroyuki Aburatani; A Matsumoto; T Kodama; F Takaku; C Fukazawa; H Itakura
Increased levels of messenger ribonucleic acid for apolipoprotein E in the spleen of probucol-treated rabbits.
The American journal of cardiology 1988;62(3):60B-65B.
1988: Hiroyuki Aburatani; A Matsumoto; H Itoh; Nobuhiro Yamada; T Murase; F Takaku; H Itakura
A study of DNA polymorphism in the apolipoprotein B gene in a Japanese population.
Atherosclerosis 1988;72(1):71-6.
1988: Hiroyuki Aburatani; A Matsumoto; H Itoh; T Murase; F Takaku; H Itakura
Deoxyribonucleic acid (DNA) polymorphism in the apolipoprotein AI gene: a study in a Japanese population.
Japanese journal of medicine 1988;27(1):56-9.
1987: S Ohnishi; E Hoh; Nobuyuki Matsuhashi; T Moriyama; T Ishikawa; Hiroyuki Aburatani; M Imawari; F Takaku; H Aoyama
[A case of eosinophilic peritonitis].
Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology 1987;84(11):2593-6.
1987: T Ishikawa; H Aoyama; H Ohtake; S Ohnishi; Hiroyuki Aburatani; M Imawari; J Shiga; F Takaku
Primary intrahepatic sclerosing cholangitis with inflammatory bowel disease.
Acta pathologica japonica 1987;37(10):1637-43.
1986: T Ishikawa; H Aoyama; Y Kobayashi; K Miyazono; S Oonishi; Hiroyuki Aburatani; T Moriyama; M Imawari; F Takaku
[A case of hemosiderosis of the liver in myelodysplastic syndrome].
Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 1986;75(10):1438-42.