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Ursula Grohmann

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Claudia Volpi; Luigina Romani; Carmine Vacca; Maria Laura Belladonna; Roberta Bianchi; Louis Boon; Antonella De Luca; Francesca Fallarino; Ursula Grohmann; Ciriana Orabona; Maria T Pallotta; Paolo Puccetti
High doses of CpG oligodeoxynucleotides stimulate a tolerogenic TLR9-TRIF pathway.
Claudia Volpi; Roberta Bianchi; Antonella De Luca; Francesca Fallarino; Bruno Gran; Ursula Grohmann; Ciriana Orabona; Paolo Puccetti; Luigina Romani; Carmine Vacca; Maria Laura Belladonna
A GpC-rich oligonucleotide acts on plasmacytoid dendritic cells to promote immune suppression.
Francesca Fallarino; Ursula Grohmann; Paolo Puccetti
Indoleamine 2,3-dioxygenase: from catalyst to signaling function.

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All Publications

2013: Claudia Volpi; Luigina Romani; Carmine Vacca; Maria Laura Belladonna; Roberta Bianchi; Louis Boon; Antonella De Luca; Francesca Fallarino; Ursula Grohmann; Ciriana Orabona; Maria T Pallotta; Paolo Puccetti
High doses of CpG oligodeoxynucleotides stimulate a tolerogenic TLR9-TRIF pathway.
Nature communications 2013;4():1852.
2012: Claudia Volpi; Roberta Bianchi; Antonella De Luca; Francesca Fallarino; Bruno Gran; Ursula Grohmann; Ciriana Orabona; Paolo Puccetti; Luigina Romani; Carmine Vacca; Maria Laura Belladonna
A GpC-rich oligonucleotide acts on plasmacytoid dendritic cells to promote immune suppression.
Journal of immunology (Baltimore, Md. : 1950) 2012;189(5):2283-9.
2012: Francesca Fallarino; Ursula Grohmann; Paolo Puccetti
Indoleamine 2,3-dioxygenase: from catalyst to signaling function.
European journal of immunology 2012;42(8):1932-7.
2012: Ciriana Orabona; Maria Teresa Pallotta; Ursula Grohmann
Different partners, opposite outcomes: a new perspective of the immunobiology of indoleamine 2,3-dioxygenase.
Molecular medicine (Cambridge, Mass.) 2012;18():834-42.
2011: Maria T Pallotta; Paolo Puccetti; Giuseppe Servillo; Carmine Vacca; Claudia Volpi; Emilia M C Mazza; Ciriana Orabona; Maria Laura Belladonna; Roberta Bianchi; Silvio Bicciato; Louis Boon; Cinzia Brunacci; Mario Calvitti; Francesca Fallarino; Maria C Fioretti; Fabio Grassi; Ursula Grohmann
Indoleamine 2,3-dioxygenase is a signaling protein in long-term tolerance by dendritic cells.
Nature immunology 2011;12(9):870-8.
2011: Francesca Fallarino; Ursula Grohmann
Using an ancient tool for igniting and propagating immune tolerance: IDO as an inducer and amplifier of regulatory T cell functions.
Current medicinal chemistry 2011;18(15):2215-21.
2011: Ciriana Orabona; Ursula Grohmann
Indoleamine 2,3-dioxygenase and regulatory function: tryptophan starvation and beyond.
Methods in molecular biology (Clifton, N.J.) 2011;677():269-80.
2010: Giovanni Luca; Francesca Fallarino; Mario Calvitti; Francesco Mancuso; Claudio Nastruzzi; Iva Arato; Giulia Falabella; Ursula Grohmann; ennio becchetti; Paolo Puccetti; Riccardo Calafiore
Xenograft of microencapsulated sertoli cells reverses T1DM in NOD mice by inducing neogenesis of beta-cells.
Transplantation 2010;90(12):1352-7.
2010: Francesca Fallarino; Claudia Volpi; Francesco Fazio; Serena Notartomaso; Carmine Vacca; Carla Busceti; Silvio Bicciato; Giuseppe Battaglia; Valeria Bruno; Paolo Puccetti; Maria C Fioretti; Ferdinando Nicoletti; Ursula Grohmann; Roberto Di Marco
Metabotropic glutamate receptor-4 modulates adaptive immunity and restrains neuroinflammation.
Nature medicine 2010;16(8):897-902.
2010: Ursula Grohmann; Vincenzo Bronte
Control of immune response by amino acid metabolism.
Immunological reviews 2010;236():243-64.
2010: Maria T Pallotta; Paolo Puccetti; Claudia Volpi; Ursula Grohmann; Ciriana Orabona; Francesca Fallarino
Proteasomal Degradation of Indoleamine 2,3-Dioxygenase in CD8 Dendritic Cells is Mediated by Suppressor of Cytokine Signaling 3 (SOCS3).
International journal of tryptophan research : IJTR 2010;3():91-7.
2009: Francesca Fallarino; Claudia Volpi; Teresa Zelante; Carmine Vacca; Mario Calvitti; Maria C Fioretti; Paolo Puccetti; Luigina Romani; Ursula Grohmann
IDO mediates TLR9-driven protection from experimental autoimmune diabetes.
Journal of immunology (Baltimore, Md. : 1950) 2009;183(10):6303-12.
2009: Francesca Fallarino; Giovanni Luca; Mario Calvitti; Francesco Mancuso; Claudio Nastruzzi; Maria C Fioretti; Ursula Grohmann; ennio becchetti; Anne Burgevin; Roland Kratzer; Peter van Endert; Louis Boon; Paolo Puccetti; Riccardo Calafiore
Therapy of experimental type 1 diabetes by isolated Sertoli cell xenografts alone.
The Journal of experimental medicine 2009;206(11):2511-26.
2009: Maria Laura Belladonna; Ciriana Orabona; Ursula Grohmann; Paolo Puccetti
TGF-beta and kynurenines as the key to infectious tolerance.
Trends in molecular medicine 2009;15(2):41-9.
2008: Ciriana Orabona; Maria T Pallotta; Claudia Volpi; Francesca Fallarino; Carmine Vacca; Roberta Bianchi; Maria Laura Belladonna; Maria C Fioretti; Ursula Grohmann; Paolo Puccetti
SOCS3 drives proteasomal degradation of indoleamine 2,3-dioxygenase (IDO) and antagonizes IDO-dependent tolerogenesis.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(52):20828-33.
2008: Maria Laura Belladonna; Claudia Volpi; Roberta Bianchi; Carmine Vacca; Ciriana Orabona; Maria T Pallotta; Louis Boon; Stefania Gizzi; Maria C Fioretti; Ursula Grohmann; Paolo Puccetti
Cutting edge: Autocrine TGF-beta sustains default tolerogenesis by IDO-competent dendritic cells.
Journal of immunology (Baltimore, Md. : 1950) 2008;181(8):5194-8.
2008: Luigina Romani; Francesca Fallarino; Antonella De Luca; Claudia Montagnoli; Carmen D'Angelo; Teresa Zelante; Carmine Vacca; Francesco Bistoni; Maria C Fioretti; Ursula Grohmann; Brahm H Segal; Paolo Puccetti
Defective tryptophan catabolism underlies inflammation in mouse chronic granulomatous disease.
Nature 2008;451(7175):211-5.
2007: Paolo Puccetti; Ursula Grohmann
IDO and regulatory T cells: a role for reverse signalling and non-canonical NF-kappaB activation.
Nature reviews. Immunology 2007;7(10):817-23.
2007: Maria Laura Belladonna; Paolo Puccetti; Ciriana Orabona; Francesca Fallarino; Carmine Vacca; Claudia Volpi; Stefania Gizzi; Maria Teresa Pallotta; Maria C Fioretti; Ursula Grohmann
Immunosuppression via tryptophan catabolism: the role of kynurenine pathway enzymes.
Transplantation 2007;84(1 Suppl):S17-20.
2007: Ursula Grohmann; Claudia Volpi; Francesca Fallarino; Silvia Bozza; Roberta Bianchi; Carmine Vacca; Ciriana Orabona; Maria Laura Belladonna; Emira Ayroldi; Giuseppe Nocentini; Louis Boon; Francesco Bistoni; Maria C Fioretti; Luigina Romani; Carlo Riccardi; Paolo Puccetti
Reverse signaling through GITR ligand enables dexamethasone to activate IDO in allergy.
Nature medicine 2007;13(5):579-86.
2007: Francesca Fallarino; Stefania Gizzi; Paolo Mosci; Ursula Grohmann; Paolo Puccetti
Tryptophan catabolism in IDO+ plasmacytoid dendritic cells.
Current drug metabolism 2007;8(3):209-16.
2006: Francesca Fallarino; Ursula Grohmann; Sylvaine You; Barbara C McGrath; Douglas R Cavener; Carmine Vacca; Ciriana Orabona; Roberta Bianchi; Maria Laura Belladonna; Claudia Volpi; Maria C Fioretti; Paolo Puccetti
Tryptophan catabolism generates autoimmune-preventive regulatory T cells.
Transplant immunology 2006;17(1):58-60.
2006: Maria Laura Belladonna; Ursula Grohmann; Paolo Guidetti; Claudia Volpi; Roberta Bianchi; Maria C Fioretti; Robert Schwarcz; Francesca Fallarino; Paolo Puccetti
Kynurenine pathway enzymes in dendritic cells initiate tolerogenesis in the absence of functional IDO.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(1):130-7.
2006: Francesca Fallarino; Ursula Grohmann; Sylvaine You; Barbara C McGrath; Douglas R Cavener; Carmine Vacca; Ciriana Orabona; Roberta Bianchi; Maria Laura Belladonna; Claudia Volpi; Pere Santamaria; Maria C Fioretti; Paolo Puccetti
The combined effects of tryptophan starvation and tryptophan catabolites down-regulate T cell receptor zeta-chain and induce a regulatory phenotype in naive T cells.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(11):6752-61.
2006: Maria Laura Belladonna; Carmine Vacca; Claudia Volpi; Antonio Giampietri; Maria C Fioretti; Paolo Puccetti; Ursula Grohmann; Franca Campanile
IL-23 neutralization protects mice from Gram-negative endotoxic shock.
Cytokine 2006;34(3-4):161-9.
2006: Ciriana Orabona; Paolo Puccetti; Carmine Vacca; Silvio Bicciato; Alessandra Luchini; Francesca Fallarino; Roberta Bianchi; enrico velardi; Katia Perruccio; Andrea Velardi; Vincenzo Bronte; Maria C Fioretti; Ursula Grohmann
Toward the identification of a tolerogenic signature in IDO-competent dendritic cells.
Blood 2006;107(7):2846-54.
2005: Ciriana Orabona; Elena Tomasello; Francesca Fallarino; Roberta Bianchi; Claudia Volpi; Silvia Bellocchio; Luigina Romani; Maria C Fioretti; Eric Vivier; Paolo Puccetti; Ursula Grohmann
Enhanced tryptophan catabolism in the absence of the molecular adapter DAP12.
European journal of immunology 2005;35(11):3111-8.
2005: Francesca Fallarino; Ciriana Orabona; Carmine Vacca; Roberta Bianchi; Stefania Gizzi; Carine Asselin-Paturel; Maria C Fioretti; Giorgio Trinchieri; Ursula Grohmann; Paolo Puccetti
Ligand and cytokine dependence of the immunosuppressive pathway of tryptophan catabolism in plasmacytoid dendritic cells.
International immunology 2005;17(11):1429-38.
2005: Carmine Vacca; Francesca Fallarino; Katia Perruccio; Ciriana Orabona; Roberta Bianchi; Stefania Gizzi; Andrea Velardi; Maria C Fioretti; Paolo Puccetti; Ursula Grohmann
CD40 ligation prevents onset of tolerogenic properties in human dendritic cells treated with CTLA-4-Ig.
Microbes and infection / Institut Pasteur 2005;7(7-8):1040-8.
2005: Ciriana Orabona; Maria Laura Belladonna; Carmine Vacca; Roberta Bianchi; Francesca Fallarino; Claudia Volpi; Stefania Gizzi; Maria C Fioretti; Ursula Grohmann; Paolo Puccetti
Cutting edge: silencing suppressor of cytokine signaling 3 expression in dendritic cells turns CD28-Ig from immune adjuvant to suppressant.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(11):6582-6.
2004: Ciriana Orabona; Ursula Grohmann; Maria Laura Belladonna; Francesca Fallarino; Carmine Vacca; Roberta Bianchi; Silvia Bozza; Claudia Volpi; Benoît L Salomon; Maria C Fioretti; Luigina Romani; Paolo Puccetti
CD28 induces immunostimulatory signals in dendritic cells via CD80 and CD86.
Nature immunology 2004;5(11):1134-42.
2004: Francesca Fallarino; Roberta Bianchi; Ciriana Orabona; Carmine Vacca; Maria Laura Belladonna; Maria C Fioretti; David V Serreze; Ursula Grohmann; Paolo Puccetti
CTLA-4-Ig activates forkhead transcription factors and protects dendritic cells from oxidative stress in nonobese diabetic mice.
The Journal of experimental medicine 2004;200(8):1051-62.
2004: Francesca Fallarino; Carine Asselin-Paturel; Carmine Vacca; Roberta Bianchi; Stefania Gizzi; Maria C Fioretti; Giorgio Trinchieri; Ursula Grohmann; Paolo Puccetti
Murine plasmacytoid dendritic cells initiate the immunosuppressive pathway of tryptophan catabolism in response to CD200 receptor engagement.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(6):3748-54.
2003: Francesca Fallarino; Ursula Grohmann; Kwang Woo Hwang; Ciriana Orabona; Carmine Vacca; Roberta Bianchi; Maria Laura Belladonna; Maria C Fioretti; Maria-Luisa Alegre; Paolo Puccetti
Modulation of tryptophan catabolism by regulatory T cells.
Nature immunology 2003;4(12):1206-12.
2003: Ursula Grohmann; Roberta Bianchi; Ciriana Orabona; Francesca Fallarino; Carmine Vacca; alessandra micheletti; Maria C Fioretti; Paolo Puccetti
Functional plasticity of dendritic cell subsets as mediated by CD40 versus B7 activation.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(5):2581-7.
2003: Ursula Grohmann; Francesca Fallarino; Roberta Bianchi; Ciriana Orabona; Carmine Vacca; Maria C Fioretti; Paolo Puccetti
A defect in tryptophan catabolism impairs tolerance in nonobese diabetic mice.
The Journal of experimental medicine 2003;198(1):153-60.
2003: Ursula Grohmann; Francesca Fallarino; Paolo Puccetti
Tolerance, DCs and tryptophan: much ado about IDO.
Trends in immunology 2003;24(5):242-8.
2003: Ursula Grohmann; Paolo Puccetti
CTLA-4, T helper lymphocytes and dendritic cells: an internal perspective of T-cell homeostasis.
Trends in molecular medicine 2003;9(4):133-5.
2003: Francesca Fallarino; Ursula Grohmann; Carmine Vacca; Ciriana Orabona; Antonio Spreca; Maria C Fioretti; Paolo Puccetti
T cell apoptosis by kynurenines.
Advances in experimental medicine and biology 2003;527():183-90.
2003: Ursula Grohmann; Francesca Fallarino; Roberta Bianchi; Carmine Vacca; Ciriana Orabona; Maria Laura Belladonna; Maria C Fioretti; Paolo Puccetti
Tryptophan catabolism in nonobese diabetic mice.
Advances in experimental medicine and biology 2003;527():47-54.
2002: Ursula Grohmann; Ciriana Orabona; Francesca Fallarino; Carmine Vacca; Filippo Calcinaro; Alberto Falorni; Paola Candeloro; Maria Laura Belladonna; Roberta Bianchi; Maria C Fioretti; Paolo Puccetti
CTLA-4-Ig regulates tryptophan catabolism in vivo.
Nature immunology 2002;3(11):1097-101.
2002: Francesca Fallarino; Ursula Grohmann; Carmine Vacca; Roberta Bianchi; Ciriana Orabona; Antonio Spreca; Maria C Fioretti; Paolo Puccetti
T cell apoptosis by tryptophan catabolism.
Cell death and differentiation 2002;9(10):1069-77.
2002: Francesca Fallarino; Ursula Grohmann; Carmine Vacca; Roberta Bianchi; Maria C Fioretti; Paolo Puccetti
CD40 ligand and CTLA-4 are reciprocally regulated in the Th1 cell proliferative response sustained by CD8(+) dendritic cells.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(3):1182-8.
2002: Maria Laura Belladonna; Jean-Christophe Renauld; Roberta Bianchi; Carmine Vacca; Francesca Fallarino; Ciriana Orabona; Maria C Fioretti; Ursula Grohmann; Paolo Puccetti
IL-23 and IL-12 have overlapping, but distinct, effects on murine dendritic cells.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(11):5448-54.
2002: Paolo Puccetti; Maria Laura Belladonna; Ursula Grohmann
Effects of IL-12 and IL-23 on antigen-presenting cells at the interface between innate and adaptive immunity.
Critical reviews in immunology 2002;22(5-6):373-90.
2002: Francesca Fallarino; Carmine Vacca; Ciriana Orabona; Maria Laura Belladonna; Roberta Bianchi; Brendan Marshall; Derin B Keskin; Andrew L Mellor; Maria C Fioretti; Ursula Grohmann; Paolo Puccetti
Functional expression of indoleamine 2,3-dioxygenase by murine CD8 alpha(+) dendritic cells.
International immunology 2002;14(1):65-8.
2001: Ursula Grohmann; Francesca Fallarino; Roberta Bianchi; Maria Laura Belladonna; Carmine Vacca; Ciriana Orabona; Catherine Uyttenhove; Maria C Fioretti; Paolo Puccetti
IL-6 inhibits the tolerogenic function of CD8 alpha+ dendritic cells expressing indoleamine 2,3-dioxygenase.
Journal of immunology (Baltimore, Md. : 1950) 2001;167(2):708-14.
2001: Ursula Grohmann; Maria Laura Belladonna; Carmine Vacca; Roberta Bianchi; Francesca Fallarino; Ciriana Orabona; Maria C Fioretti; Paolo Puccetti
Positive regulatory role of IL-12 in macrophages and modulation by IFN-gamma.
Journal of immunology (Baltimore, Md. : 1950) 2001;167(1):221-7.
2001: Ursula Grohmann; Francesca Fallarino; S Silla; Roberta Bianchi; Maria Laura Belladonna; Carmine Vacca; alessandra micheletti; Maria C Fioretti; Paolo Puccetti
CD40 ligation ablates the tolerogenic potential of lymphoid dendritic cells.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(1):277-83.
2000: Francesca Fallarino; Ursula Grohmann; Roberta Bianchi; Carmine Vacca; Maria C Fioretti; Paolo Puccetti
Th1 and Th2 cell clones to a poorly immunogenic tumor antigen initiate CD8+ T cell-dependent tumor eradication in vivo.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(10):5495-501.
2000: Ursula Grohmann; Roberta Bianchi; Maria Laura Belladonna; S Silla; Francesca Fallarino; Maria C Fioretti; Paolo Puccetti
IFN-gamma inhibits presentation of a tumor/self peptide by CD8 alpha- dendritic cells via potentiation of the CD8 alpha+ subset.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(3):1357-63.
2000: Ursula Grohmann; J Van Snick; Franca Campanile; S Silla; Antonio Giampietri; Carmine Vacca; Jean-Christophe Renauld; Maria C Fioretti; Paolo Puccetti
IL-9 protects mice from Gram-negative bacterial shock: suppression of TNF-alpha, IL-12, and IFN-gamma, and induction of IL-10.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(8):4197-203.
2000: Antonio Giampietri; Ursula Grohmann; Carmine Vacca; Maria C Fioretti; Paolo Puccetti; Franca Campanile
Dual effect of IL-4 on resistance to systemic gram-negative infection and production of TNF-alpha.
Cytokine 2000;12(4):417-21.
2000: Ursula Grohmann; Ciriana Orabona; R Bianchi; Maria Laura Belladonna; Maria C Fioretti; Paolo Puccetti
IL-12 induces SDS-stable class II alphabeta dimers in murine dendritic cells.
Cytokine 2000;12(4):401-4.
1999: Ursula Grohmann; Roberta Bianchi; Maria Laura Belladonna; Carmine Vacca; S Silla; Emira Ayroldi; Maria C Fioretti; Paolo Puccetti
IL-12 acts selectively on CD8 alpha- dendritic cells to enhance presentation of a tumor peptide in vivo.
Journal of immunology (Baltimore, Md. : 1950) 1999;163(6):3100-5.
1999: Roberta Bianchi; Ursula Grohmann; Carmine Vacca; Maria Laura Belladonna; Maria C Fioretti; Paolo Puccetti
Autocrine IL-12 is involved in dendritic cell modulation via CD40 ligation.
Journal of immunology (Baltimore, Md. : 1950) 1999;163(5):2517-21.
1999: Ursula Grohmann; Maria Laura Belladonna; Roberta Bianchi; Ciriana Orabona; S Silla; G Squillacioti; Maria C Fioretti; Paolo Puccetti
Immunogenicity of tumor peptides: importance of peptide length and stability of peptide/MHC class II complex.
Cancer immunology, immunotherapy : CII 1999;48(4):195-203.
1998: Emira Ayroldi; Ornella Zollo; Lorenza Cannarile; F D' Adamio; Ursula Grohmann; Domenico Vittorio Delfino; Carlo Riccardi
Interleukin-6 (IL-6) prevents activation-induced cell death: IL-2-independent inhibition of Fas/fasL expression and cell death.
Blood 1998;92(11):4212-9.
1998: Ursula Grohmann; Maria Laura Belladonna; Roberta Bianchi; Ciriana Orabona; Emira Ayroldi; Maria C Fioretti; Paolo Puccetti
IL-12 acts directly on DC to promote nuclear localization of NF-kappaB and primes DC for IL-12 production.
Immunity 1998;9(3):315-23.
1998: Maria Laura Belladonna; Ursula Grohmann; Roberta Bianchi; Emira Ayroldi; D Surace; Paolo Puccetti; Maria C Fioretti
The role of IL-12 in the induction of an immune response to a tumor/self peptide: prevention and reversion of anergy.
Journal of chemotherapy (Florence, Italy) 1998;10(2):157-9.
1998: Ursula Grohmann; Maria C Fioretti; Roberta Bianchi; Maria Laura Belladonna; Emira Ayroldi; D Surace; S Silla; Paolo Puccetti
Dendritic cells, interleukin 12, and CD4+ lymphocytes in the initiation of class I-restricted reactivity to a tumor/self peptide.
Critical reviews in immunology 1998;18(1-2):87-98.
1997: Ursula Grohmann; S Silla; Maria Laura Belladonna; Roberta Bianchi; Ciriana Orabona; Paolo Puccetti; Maria C Fioretti
Circulating levels of IL-10 are critically related to growth and rejection patterns of murine mastocytoma cells.
Cellular immunology 1997;181(2):109-19.
1997: Ursula Grohmann; Roberta Bianchi; Emira Ayroldi; Maria Laura Belladonna; D Surace; Maria C Fioretti; Paolo Puccetti
A tumor-associated and self antigen peptide presented by dendritic cells may induce T cell anergy in vivo, but IL-12 can prevent or revert the anergic state.
Journal of immunology (Baltimore, Md. : 1950) 1997;158(8):3593-602.
1997: Ursula Grohmann; Roberta Bianchi; Maria Laura Belladonna; S Silla; D Surace; Maria C Fioretti; Paolo Puccetti
Dendritic cells and interleukin 12 as adjuvants for tumor-specific vaccines.
Advances in experimental medicine and biology 1997;417():579-82.
1996: Maria Laura Belladonna; Maria C Fioretti; Roberta Bianchi; Paolo Puccetti; Ursula Grohmann
A retroviral peptide encoded by mutated env p15E gene is recognized by specific CD8+ T lymphocytes on drug-treated murine mastocytoma P815.
International journal of immunopharmacology 1996;18(10):563-76.
1996: Roberta Bianchi; Ursula Grohmann; Maria Laura Belladonna; S Silla; Francesca Fallarino; Emira Ayroldi; Maria C Fioretti; Paolo Puccetti
IL-12 is both required and sufficient for initiating T cell reactivity to a class I-restricted tumor peptide (P815AB) following transfer of P815AB-pulsed dendritic cells.
Journal of immunology (Baltimore, Md. : 1950) 1996;157(4):1589-97.
1996: F Campanile; A Giampietri; Ursula Grohmann; Maria Laura Belladonna; Maria C Fioretti; Paolo Puccetti
Evidence for tumor necrosis factor alpha as a mediator of the toxicity of a cyclooxygenase inhibitor in Gram-negative sepsis.
European journal of pharmacology 1996;307(2):191-9.
1995: Grazia Graziani; Isabella Faraoni; Ursula Grohmann; Roberta Bianchi; L Binaglia; G P Margison; A J Watson; Laura Orlando; Enzo Bonmassar; Stefania D'Atri
O6-alkylguanine-DNA alkyltransferase attenuates triazene-induced cytotoxicity and tumor cell immunogenicity in murine L1210 leukemia.
Cancer research 1995;55(24):6231-6.
1995: Ursula Grohmann; Roberta Bianchi; Maria C Fioretti; Francesca Fallarino; L Binaglia; Catherine Uyttenhove; Aline Van Pel; Thierry Boon; Paolo Puccetti
CD8+ cell activation to a major mastocytoma rejection antigen, P815AB: requirement for tum- or helper peptides in priming for skin test reactivity to a P815AB-related peptide.
European journal of immunology 1995;25(10):2797-802.
1995: Ursula Grohmann; Paolo Puccetti; Maria Laura Belladonna; Francesca Fallarino; Roberta Bianchi; L Binaglia; K Sagakuchi; M G Mage; Ettore Appella; Maria C Fioretti
Multiple point mutations in an endogenous retroviral gene confer high immunogenicity on a drug-treated murine tumor.
Journal of immunology (Baltimore, Md. : 1950) 1995;154(9):4630-41.
1994: Stefania D'Atri; L Romani; Enzo Bonmassar; Ursula Grohmann; Maria Tricarico; S E Christmas; M Moore
Untreated or drug-treated tumor cells are differentially recognized by allogeneic lymphocytes.
International journal of immunopharmacology 1994;16(7):569-79.
1994: Paolo Puccetti; Roberta Bianchi; Maria C Fioretti; Emira Ayroldi; Catherine Uyttenhove; Aline Van Pel; Thierry Boon; Ursula Grohmann
Use of a skin test assay to determine tumor-specific CD8+ T cell reactivity.
European journal of immunology 1994;24(6):1446-52.
1994: Luigina Romani; Paolo Puccetti; Antonella Mencacci; Elio Cenci; Roberta Spaccapelo; L Tonnetti; Ursula Grohmann; Francesco Bistoni
Neutralization of IL-10 up-regulates nitric oxide production and protects susceptible mice from challenge with Candida albicans.
Journal of immunology (Baltimore, Md. : 1950) 1994;152(7):3514-21.
1994: Ursula Grohmann; Maria Laura Belladonna; M Allegrucci; S Silla; E Schiaffella; Maria C Fioretti; Paolo Puccetti
Endogenous retroviral gp70 genes of the murine lymphoma L5178Y: analysis of restriction fragment polymorphism upon induction of drug-mediated immunogenicity.
Viral immunology 1994;7(4):155-67.
1993: Ursula Grohmann; Maria C Fioretti; L Binaglia; Maria Laura Belladonna; Roberta Bianchi; Paolo Puccetti
Immunogenic properties of retroviral protein P15E from drug-treated murine mastocytoma P815.
International journal of cancer. Journal international du cancer 1993;55(2):344-50.
1993: Ursula Grohmann; L Binaglia; Paolo Puccetti; Maria C Fioretti
Cell-mediated immunity to chemically xenogenized tumors--VI. The effect of cell treatment with retroviral env antisense oligonucleotides.
International journal of immunopharmacology 1993;15(5):567-72.
1993: F Campanile; A Giampietri; Ursula Grohmann; L Binaglia; Maria C Fioretti; Paolo Puccetti
Accelerated hematopoietic recovery and protective effect of the cyclooxygenase inhibitor indomethacin in bacterial infection of neutropenic mice.
Cellular immunology 1993;147(2):341-52.
1992: Luigina Romani; Antonella Mencacci; Elio Cenci; Paolo Mosci; G Vitellozzi; Ursula Grohmann; Paolo Puccetti; Francesco Bistoni
Course of primary candidiasis in T cell-depleted mice infected with attenuated variant cells.
The Journal of infectious diseases 1992;166(6):1384-92.
1992: Luigina Romani; Elio Cenci; Antonella Mencacci; Roberta Spaccapelo; Ursula Grohmann; Paolo Puccetti; Francesco Bistoni
Gamma interferon modifies CD4+ subset expression in murine candidiasis.
Infection and immunity 1992;60(11):4950-2.
1992: Ursula Grohmann; Paolo Puccetti; Luigina Romani; L Binaglia; Roberta Bianchi; Maria Laura Belladonna; Stephen Ullrich; Ettore Appella; Maria C Fioretti
Immunogenic tumor variants induced by drug treatment of the L5178Y lymphoma: search for serologically defined antigens at the clonal level.
International journal of cancer. Journal international du cancer 1992;52(3):372-7.
1992: M Allegrucci; Ursula Grohmann; P Fuschiotti; Roberta Bianchi; Paolo Puccetti; Maria C Fioretti
Molecular and genomic aspects of xenogenizing-alkylating drugs.
Pharmacological research : the official journal of the Italian Pharmacological Society 1992;26 Suppl 2():24-5.
1992: Ursula Grohmann; L Binaglia; Roberta Bianchi; Paolo Puccetti; Maria C Fioretti
Immune recognition of drug-induced tumor antigens: a study with a nonimmunogenic, revertant clone.
Pharmacological research : the official journal of the Italian Pharmacological Society 1992;26 Suppl 2():186-7.
1992: Roberta Bianchi; Ursula Grohmann; Maria C Fioretti; Paolo Puccetti
Antagonistic effect of IL-2 on DTIC-induced impairment of tumor-specific cell-mediated immunity in vitro.
Pharmacological research : the official journal of the Italian Pharmacological Society 1992;26 Suppl 2():106-7.
1992: Luigina Romani; Antonella Mencacci; Ursula Grohmann; S Mocci; Paolo Mosci; Paolo Puccetti; Francesco Bistoni
Neutralizing antibody to interleukin 4 induces systemic protection and T helper type 1-associated immunity in murine candidiasis.
The Journal of experimental medicine 1992;176(1):19-25.
1992: Roberta Bianchi; Maria C Fioretti; Ursula Grohmann; L Binaglia; Luigina Romani; Paolo Puccetti
Tumor-specific L3T4+ and Lyt-2+ lymphocytes in mice primed to mutagenized cell variants.
International journal of immunopharmacology 1992;14(5):915-21.
1992: P Fuschiotti; Ursula Grohmann; M Allegrucci; B Nardelli; Maria C Fioretti
Genomic aspects of drug-induced xenogenization of murine tumors.
Pharmacological research : the official journal of the Italian Pharmacological Society 1992;25 Suppl 1():19-20.
1991: Ursula Grohmann; Luigina Romani; L Binaglia; Maria C Fioretti; Paolo Puccetti
Intrasplenic immunization for the induction of humoral and cell-mediated immunity to nitrocellulose-bound antigen.
Journal of immunological methods 1991;137(1):9-15.
1990: Roberta Bianchi; Maria C Fioretti; Luigina Romani; Ursula Grohmann; Elio Cenci; Paolo Puccetti
T-cell subsets, IFN-gamma production and efferent specificity in anti-parental tumor immunity induced by mouse sensitization with xenogenized variant cells.
International journal of cancer. Journal international du cancer 1990;46(4):653-7.
1990: Ursula Grohmann; P Fuschiotti; Roberta Bianchi; M Allegrucci; Maria C Fioretti
Biochemical aspects of mutagen-induced antigenicity.
Pharmacological research : the official journal of the Italian Pharmacological Society 1990;22 Suppl 1():43-4.
1990: Ursula Grohmann; Stephen Ullrich; M G Mage; Ettore Appella; Maria C Fioretti; Paolo Puccetti; Luigina Romani
Identification and immunogenic properties of an 80-kDa surface antigen on a drug-treated tumor variant: relationship to MuLV gp70.
European journal of immunology 1990;20(3):629-36.
1990: Luigina Romani; Ursula Grohmann; Paolo Puccetti; M A Rossi; Maria C Fioretti
Cell-mediated immunity to chemically xenogenized tumors. V. Failure of novel antigens to increase the frequency of tumor-specific cytotoxic T cells.
International journal of immunopharmacology 1990;12(7):743-9.
1989: Luigina Romani; Paolo Puccetti; Ursula Grohmann; Elio Cenci; M G Mage; Maria C Fioretti
Cell-mediated immunity to chemically xenogenized tumors--IV. Production of lymphokine activity by, and in response to, highly immunogenic cells.
International journal of immunopharmacology 1989;11(5):537-42.
1988: Ursula Grohmann; Luigina Romani; G B Principato; Paolo Puccetti; M G Mage; Maria C Fioretti
Generation of monoclonal antibodies to a chemically xenogenized murine lymphoma.
Pharmacological research communications 1988;20(5):443-4.
1988: Luigina Romani; Ursula Grohmann; Paolo Puccetti; B Nardelli; M G Mage; Maria C Fioretti
Cell-mediated immunity to chemically xenogenized tumors. II. Evidence for accessory function and self-antigen presentation by a highly immunogenic tumor variant.
Cellular immunology 1988;111(2):365-78.
1988: Ursula Grohmann; Paolo Puccetti; Maria C Fioretti; M G Mage; Luigina Romani
Cell-mediated immunity to chemically xenogenized tumors--III. Generation of monoclonal antibodies interfering with reactivity to novel antigens.
International journal of immunopharmacology 1988;10(7):803-9.
1988: Luigina Romani; Ursula Grohmann; F Fazioli; Paolo Puccetti; M G Mage; Maria C Fioretti
Cell-mediated immunity to chemically xenogenized tumors. I. Inhibition by specific antisera and H-2 association of the novel antigens.
Cancer immunology, immunotherapy : CII 1988;26(1):48-54.