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Irina Gromova

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Teresa Cabezón; Julio E Celis; Pavel Gromov; Irina Gromova; Niels Kroman; Reza Serizawa; Vera Timmermans Wielenga; José M A Moreira
Proteomic profiling of triple-negative breast carcinomas in combination with a three-tier orthogonal technology approach identifies Mage-A4 as potential therapeutic target in estrogen receptor negative breast cancer.
Irina Gromova; Niels Kroman; Guido Sauter; Ronald Simon; Vera Timmermans Wielenga; Pavel Gromov; José M A Moreira
Immunoexpression analysis and prognostic value of BLCAP in breast cancer.
José M A Moreira; Teresa Cabezón; Irina Gromova; Pavel Gromov; Vera Timmermans-Wielenga; Isidro Machado; Antonio Llombart Bosch; Niels Kroman; Fritz Rank; Julio E Celis
Tissue proteomics of the human mammary gland: towards an abridged definition of the molecular phenotypes underlying epithelial normalcy.

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All Publications

2013: Teresa Cabezón; Julio E Celis; Pavel Gromov; Irina Gromova; Niels Kroman; Reza Serizawa; Vera Timmermans Wielenga; José M A Moreira
Proteomic profiling of triple-negative breast carcinomas in combination with a three-tier orthogonal technology approach identifies Mage-A4 as potential therapeutic target in estrogen receptor negative breast cancer.
Molecular & cellular proteomics : MCP 2013;12(2):381-94.
2012: Irina Gromova; Niels Kroman; Guido Sauter; Ronald Simon; Vera Timmermans Wielenga; Pavel Gromov; José M A Moreira
Immunoexpression analysis and prognostic value of BLCAP in breast cancer.
PloS one 2012;7(9):e45967.
2010: José M A Moreira; Teresa Cabezón; Irina Gromova; Pavel Gromov; Vera Timmermans-Wielenga; Isidro Machado; Antonio Llombart Bosch; Niels Kroman; Fritz Rank; Julio E Celis
Tissue proteomics of the human mammary gland: towards an abridged definition of the molecular phenotypes underlying epithelial normalcy.
Molecular oncology 2010;4(6):539-61.
2010: Pavel Gromov; Irina Gromova; Esbern Friis; Vera Timmermans-Wielenga; Fritz Rank; Ronald Simon; Guido Sauter; José M A Moreira
Proteomic profiling of mammary carcinomas identifies C7orf24, a gamma-glutamyl cyclotransferase, as a potential cancer biomarker.
Journal of proteome research 2010;9(8):3941-53.
2010: Pavel Gromov; Irina Gromova; Jakob Bunkenborg; Teresa Cabezon; José M A Moreira; Vera Timmermans-Wielenga; Peter Roepstorff; Fritz Rank; Julio E Celis
Up-regulated proteins in the fluid bathing the tumour cell microenvironment as potential serological markers for early detection of cancer of the breast.
Molecular oncology 2010;4(1):65-89.
2010: Simon Bekker-Jensen; Jannie Rendtlew Danielsen; Kasper Fugger; Irina Gromova; Annika Nerstedt; Claudia Lukas; Jiri Bartek; Jiri Lukas; Niels Mailand
HERC2 coordinates ubiquitin-dependent assembly of DNA repair factors on damaged chromosomes.
Nature cell biology 2010;12(1):80-6; sup pp 1-12.
2010: José M A Moreira; Gita Ohlsson; Pavel Gromov; Ronald Simon; Guido Sauter; Julio E Celis; Irina Gromova
Bladder cancer-associated protein, a potential prognostic biomarker in human bladder cancer.
Molecular & cellular proteomics : MCP 2010;9(1):161-77.
2009: Julio E Celis; Pavel Gromov; Irina Gromova; Naoko Honma; Takuji Iwase; José M A Moreira; Futoshi Akiyama; Teresa Cabezón; Vera Timmermans-Wielenga; Fritz Rank
Molecular characterization of apocrine carcinoma of the breast: validation of an apocrine protein signature in a well-defined cohort.
Molecular oncology 2009;3(3):220-37.
2008: Pavel Gromov; Julio E Celis; Irina Gromova; Fritz Rank; Vera Timmermans-Wielenga; José M A Moreira
A single lysis solution for the analysis of tissue samples by different proteomic technologies.
Molecular oncology 2008;2(4):368-79.
2008: Julio E Celis; Pavel Gromov; Teresa Cabezón; José M A Moreira; Esbern Friis; Karin Jirström; Antonio Llombart Bosch; Vera Timmermans-Wielenga; Fritz Rank; Irina Gromova
15-prostaglandin dehydrogenase expression alone or in combination with ACSM1 defines a subgroup of the apocrine molecular subtype of breast carcinoma.
Molecular & cellular proteomics : MCP 2008;7(10):1795-809.
2008: Pavel Gromov; José M A Moreira; Irina Gromova; Julio E Celis
Proteomic strategies in bladder cancer: From tissue to fluid and back.
Proteomics. Clinical applications 2008;2(7-8):974-88.
2008: José M A Moreira; Tao Shen; Gita Ohlsson; Pavel Gromov; Irina Gromova; Julio E Celis
A combined proteome and ultrastructural localization analysis of 14-3-3 proteins in transformed human amnion (AMA) cells: definition of a framework to study isoform-specific differences.
Molecular & cellular proteomics : MCP 2008;7(7):1225-40.
2007: Julio E Celis; Irina Gromova; Teresa Cabezón; Pavel Gromov; Tao Shen; Vera Timmermans-Wielenga; Fritz Rank; José M A Moreira
Identification of a subset of breast carcinomas characterized by expression of cytokeratin 15: relationship between CK15+ progenitor/amplified cells and pre-malignant lesions and invasive disease.
Molecular oncology 2007;1(3):321-49.
2007: Julio E Celis; José M A Moreira; Irina Gromova; Teresa Cabezón; Pavel Gromov; Tao Shen; Vera Timmermans; Fritz Rank
Characterization of breast precancerous lesions and myoepithelial hyperplasia in sclerosing adenosis with apocrine metaplasia.
Molecular oncology 2007;1(1):97-119.
2006: Julio E Celis; Irina Gromova; Pavel Gromov; José M A Moreira; Teresa Cabezón; Esbern Friis; Fritz Rank
Molecular pathology of breast apocrine carcinomas: a protein expression signature specific for benign apocrine metaplasia.
FEBS letters 2006;580(12):2935-44.
2006: Julio E Celis; Pavel Gromov; José M A Moreira; Teresa Cabezón; Esbern Friis; Ilse Vejborg; Gottfried Proess; Fritz Rank; Irina Gromova
Apocrine cysts of the breast: biomarkers, origin, enlargement, and relation with cancer phenotype.
Molecular & cellular proteomics : MCP 2006;5(3):462-83.
2005: Henriette Andersen; Jakob Mejlvang; Shaukat Mahmood; Irina Gromova; Pavel Gromov; Eugene Lukanidin; Marina Kriajevska; J Kilian Mellon; Eugene Tulchinsky
Immediate and delayed effects of E-cadherin inhibition on gene regulation and cell motility in human epidermoid carcinoma cells.
Molecular and cellular biology 2005;25(20):9138-50.
2005: Julio E Celis; José M A Moreira; Teresa Cabezón; Pavel Gromov; Esbern Friis; Fritz Rank; Irina Gromova
Identification of extracellular and intracellular signaling components of the mammary adipose tissue and its interstitial fluid in high risk breast cancer patients: toward dissecting the molecular circuitry of epithelial-adipocyte stromal cell interactions.
Molecular & cellular proteomics : MCP 2005;4(4):492-522.
2005: Julio E Celis; José M A Moreira; Irina Gromova; Teresa Cabezon; Ulrik Ralfkiaer; Per Guldberg; Per thor Straten; Henning Mouridsen; Esbern Friis; Dorte Holm; Fritz Rank; Pavel Gromov
Towards discovery-driven translational research in breast cancer.
The FEBS journal 2005;272(1):2-15.
2004: Julio E Celis; Irina Gromova; José M A Moreira; Teresa Cabezon; Pavel Gromov
Impact of proteomics on bladder cancer research.
Pharmacogenomics 2004;5(4):381-94.
2004: Julio E Celis; Pavel Gromov; Teresa Cabezón; José M A Moreira; Noona Ambartsumian; Kerstin Sandelin; Fritz Rank; Irina Gromova
Proteomic characterization of the interstitial fluid perfusing the breast tumor microenvironment: a novel resource for biomarker and therapeutic target discovery.
Molecular & cellular proteomics : MCP 2004;3(4):327-44.
2003: Julio E Celis; Pavel Gromov; Irina Gromova; José M A Moreira; Teresa Cabezón; Noona Ambartsumian; Mariam Grigorian; Eugene Lukanidin; Per thor Straten; Per Guldberg; Jirina Bartkova; Jiri Bartek; Jiri Lukas; Claudia Lukas; Anne E Lykkesfeldt; Marja Jäättelä; Peter Roepstorff; Lars Bolund; Torben F Ørntoft; Nils Brünner; Jens Overgaard; Kerstin Sandelin; Mogens Blichert-Toft; Henning Mouridsen; Fritz Rank
Integrating proteomic and functional genomic technologies in discovery-driven translational breast cancer research.
Molecular & cellular proteomics : MCP 2003;2(6):369-77.
2003: Pavel Gromov; Gunhild Lange Skovgaard; Hildur Palsdottir; Irina Gromova; Morten Østergaard; Julio E Celis
Protein profiling of the human epidermis from the elderly reveals up-regulation of a signature of interferon-gamma-induced polypeptides that includes manganese-superoxide dismutase and the p85beta subunit of phosphatidylinositol 3-kinase.
Molecular & cellular proteomics : MCP 2003;2(2):70-84.
2002: Pavel Gromov; Morten Østergaard; Irina Gromova; Julio E Celis
Human proteomic databases: a powerful resource for functional genomics in health and disease.
Progress in biophysics and molecular biology 2002;80(1-2):3-22.
2002: Julio E Celis; Pamela Celis; Hildur Palsdottir; Morten Østergaard; Pavel Gromov; Hanne Primdahl; Torben F Ørntoft; Hans Wolf; Ariana Celis; Irina Gromova
Proteomic strategies to reveal tumor heterogeneity among urothelial papillomas.
Molecular & cellular proteomics : MCP 2002;1(4):269-79.
2002: Irina Gromova; Pavel Gromov; Julio E Celis
bc10: A novel human bladder cancer-associated protein with a conserved genomic structure downregulated in invasive cancer.
International journal of cancer. Journal international du cancer 2002;98(4):539-46.
2001: Irina Gromova; Pavel Gromov; Julio E Celis
A novel member of the glycosyltransferase family, beta 3 Gn-T2, highly downregulated in invasive human bladder transitional cell carcinomas.
Molecular carcinogenesis 2001;32(2):61-72.
2000: Julio E Celis; Mogens Kruhøffer; Irina Gromova; Casper Frederiksen; M Ostergaard; Thomas Thykjaer; Pavel Gromov; J Yu; H Pálsdóttir; Nils E Magnusson; Torben F Orntoft
Gene expression profiling: monitoring transcription and translation products using DNA microarrays and proteomics.
FEBS letters 2000;480(1):2-16.
1999: Julio E Celis; M Ostergaard; HH Rasmussen; Pavel Gromov; Irina Gromova; H Varmark; Hildur Palsdottir; Nils E Magnusson; I Andersen; B Basse; JB Lauridsen; G Ratz; Hans Wolf; Torben F Orntoft; Pamela Celis; Ariana Celis
A comprehensive protein resource for the study of bladder cancer: http://biobase.dk/cgi-bin/celis.
Electrophoresis 1999;20(2):300-9.
1999: Irina Gromova; Pavel Gromov; Julio E Celis
Identification of true differentially expressed mRNAs in a pair of human bladder transitional cell carcinomas using an improved differential display procedure.
Electrophoresis 1999;20(2):241-8.
1998: Irina Gromova; H Biersack; S Jensen; O F Nielsen; Ole Westergaard; Anni H Andersen
Characterization of DNA topoisomerase II alpha/beta heterodimers in HeLa cells.
Biochemistry 1998;37(47):16645-52.
1998: Irina Gromova; Pavel Gromov; H Wolf; Julio E Celis
Protein abundancy and mRNA levels of the adipocyte-type fatty acid binding protein correlate in non-invasive and invasive bladder transitional cell carcinomas.
International journal of oncology 1998;13(2):379-83.
1998: Julio E Celis; M Ostergaard; Niels A Jensen; Irina Gromova; HH Rasmussen; Pavel Gromov
Human and mouse proteomic databases: novel resources in the protein universe.
FEBS letters 1998;430(1-2):64-72.
1998: Pavel Gromov; Julio E Celis; C Hansen; Niels Tommerup; Irina Gromova; Peder Madsen
Human rab11a: transcription, chromosome mapping and effect on the expression levels of host GTP-binding proteins.
FEBS letters 1998;429(3):359-64.
1996: Julio E Celis; Pavel Gromov; M Ostergaard; Peder Madsen; Bent Honoré; K Dejgaard; E Olsen; Henrik Vorum; D B Kristensen; Irina Gromova; A Haunsø; J Van Damme; M Puype; J Vandekerckhove; HH Rasmussen
Human 2-D PAGE databases for proteome analysis in health and disease: http://biobase.dk/cgi-bin/celis.
FEBS letters 1996;398(2-3):129-34.
1996: H Biersack; S Jensen; Irina Gromova; I S Nielsen; Ole Westergaard; Anni H Andersen
Active heterodimers are formed from human DNA topoisomerase II alpha and II beta isoforms.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(16):8288-93.
1995: Irina Gromova; O F Nielsen; Sergey V Razin
Long-range fragmentation of the eukaryotic genome by exogenous and endogenous nucleases proceeds in a specific fashion via preferential DNA cleavage at matrix attachment sites.
The Journal of biological chemistry 1995;270(31):18685-90.
1995: Sergey V Razin; Irina Gromova
The channels model of nuclear matrix structure.
BioEssays : news and reviews in molecular, cellular and developmental biology 1995;17(5):443-50.
1995: Irina Gromova; Bo Thomsen; Sergey V Razin
Different topoisomerase II antitumor drugs direct similar specific long-range fragmentation of an amplified c-MYC gene locus in living cells and in high-salt-extracted nuclei.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(1):102-6.
1993: Irina Gromova; E Kjeldsen; J Q Svejstrup; J Alsner; K Christiansen; Ole Westergaard
Characterization of an altered DNA catalysis of a camptothecin-resistant eukaryotic topoisomerase I.
Nucleic acids research 1993;21(3):593-600.
1993: Sergey V Razin; R Hancock; Olga V Iarovaia; O Westergaard; Irina Gromova; G P Georgiev
Structural-functional organization of chromosomal DNA domains.
Cold Spring Harbor symposia on quantitative biology 1993;58():25-35.
1992: E Kjeldsen; J Q Svejstrup; Irina Gromova; J Alsner; Ole Westergaard
Camptothecin inhibits both the cleavage and religation reactions of eukaryotic DNA topoisomerase I.
Journal of molecular biology 1992;228(4):1025-30.
1991: J Q Svejstrup; K Christiansen; Irina Gromova; Anni H Andersen; Ole Westergaard
New technique for uncoupling the cleavage and religation reactions of eukaryotic topoisomerase I. The mode of action of camptothecin at a specific recognition site.
Journal of molecular biology 1991;222(3):669-78.