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Angela Gronenborn

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TOP 3
Leonardus M I Koharudin; Lin Liu; Angela M Gronenborn
Different 3D domain-swapped oligomeric cyanovirin-N structures suggest trapped folding intermediates.
Matthew J Whitley; Sireesha Kollipara; William Furey; Angela M Gronenborn
Burkholderia oklahomensis agglutinin is a canonical two-domain OAA-family lectin: structures, carbohydrate binding and anti-HIV activity.
Elena Matei; Stefan Oscarson; Angela Simona Infantino; Sabine André; Hans-Joachim Gabius; Anja Glinschert; Angela M Gronenborn
Fluorinated Carbohydrates as Lectin Ligands: Dissecting Glycan-Cyanovirin Interactions by Using (19) F NMR Spectroscopy.

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All Publications

2013: Leonardus M I Koharudin; Lin Liu; Angela M Gronenborn
Different 3D domain-swapped oligomeric cyanovirin-N structures suggest trapped folding intermediates.
Proceedings of the National Academy of Sciences of the United States of America 2013;110(19):7702-7.
2013: Matthew J Whitley; Sireesha Kollipara; William Furey; Angela M Gronenborn
Burkholderia oklahomensis agglutinin is a canonical two-domain OAA-family lectin: structures, carbohydrate binding and anti-HIV activity.
The FEBS journal 2013;280(9):2056-67.
2013: Elena Matei; Stefan Oscarson; Angela Simona Infantino; Sabine André; Hans-Joachim Gabius; Anja Glinschert; Angela M Gronenborn
Fluorinated Carbohydrates as Lectin Ligands: Dissecting Glycan-Cyanovirin Interactions by Using (19) F NMR Spectroscopy.
Chemistry (Weinheim an der Bergstrasse, Germany) 2013;19(17):5364-74.
2013: Junpeng Yan; Chuanping Wang; Jinwoo Ahn; Maria Delucia; Marcin Golczak; Angela M Gronenborn; Caili Hao; Sarabpreet Kaur; Jennifer Mehrens; Krzysztof Palczewski; Jacek Skowronski
Tetramerization of SAMHD1 Is Required for Biological Activity and Inhibition of HIV Infection.
The Journal of biological chemistry 2013;288(15):10406-17.
2013: Leonardus M I Koharudin; Angela M Gronenborn
Sweet entanglements-protein: Glycan interactions in two HIV-inactivating lectin families.
Biopolymers 2013;99(3):196-202.
2013: Fangling Ji; Jinwon Jung; Leonardus M I Koharudin; Angela M Gronenborn
The human W42R γD-crystallin mutant structure provides a link between congenital and age-related cataracts.
The Journal of biological chemistry 2013;288(1):99-109.
2012: Haitao Yang; Peijun Zhang; Gongpu Zhao; Qi Zhao; Christopher Aiken; Angela M Gronenborn; Xiaoyun Ji; Jiying Ning; Yong Xiong
Structural insight into HIV-1 capsid recognition by rhesus TRIM5α.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(45):18372-7.
2012: Guangjin Hou; Jinwoo Ahn; In-Ja L Byeon; Angela M Gronenborn; Tatyana Polenova
Recoupling of chemical shift anisotropy by R-symmetry sequences in magic angle spinning NMR spectroscopy.
The Journal of chemical physics 2012;137(13):134201.
2012: Leonardus M I Koharudin; Sireesha Kollipara; Christopher Aiken; Angela M Gronenborn
Structural insights into the anti-HIV activity of the Oscillatoria agardhii agglutinin homolog lectin family.
The Journal of biological chemistry 2012;287(40):33796-811.
2012: Xin Wang; Angela M Gronenborn; Elena Matei; Olof Ramström; Mingdi Yan
Direct measurement of glyconanoparticles and lectin interactions by isothermal titration calorimetry.
Analytical chemistry 2012;84(10):4248-52.
2012: In-Ja L Byeon; Angela M Gronenborn; Yun Han; Guangjin Hou; Jinwon Jung; Jinwoo Ahn; Chang-Hyeock Byeon; Christopher L Suiter; Tatyana Polenova
Motions on the millisecond time scale and multiple conformations of HIV-1 capsid protein: implications for structural polymorphism of CA assemblies.
Journal of the American Chemical Society 2012;134(14):6455-66.
2012: Jinwoo Ahn; Maria DeLucia; Angela M Gronenborn; Caili Hao; Jennifer Mehrens; Chuanping Wang; Junpeng Yan; Jacek Skowronski
HIV/simian immunodeficiency virus (SIV) accessory virulence factor Vpx loads the host cell restriction factor SAMHD1 onto the E3 ubiquitin ligase complex CRL4DCAF1.
The Journal of biological chemistry 2012;287(15):12550-8.
2012: Murali Jayaraman; Ravindra Kodali; Leonardus M I Koharudin; Rakesh Mishra; Ashwani K Thakur; Angela M Gronenborn; Ronald Wetzel
Kinetically competing huntingtin aggregation pathways control amyloid polymorphism and properties.
Biochemistry 2012;51(13):2706-16.
2012: Fangling Ji; Jinwon Jung; Angela M Gronenborn
Structural and biochemical characterization of the childhood cataract-associated R76S mutant of human γD-crystallin.
Biochemistry 2012;51(12):2588-96.
2012: Lin Liu; Ivet Bahar; In-Ja L Byeon; Angela M Gronenborn
Domain swapping proceeds via complete unfolding: a 19F- and 1H-NMR study of the Cyanovirin-N protein.
Journal of the American Chemical Society 2012;134(9):4229-35.
2012: Troy C Krzysiak; James Thompson; David Baker; Jinwon Jung; Angela M Gronenborn
APOBEC2 is a monomer in solution: implications for APOBEC3G models.
Biochemistry 2012;51(9):2008-17.
2012: Xin Meng; Jiying Ning; Ernest Yufenyuy; Jinwoo Ahn; Christopher Aiken; Maria Delucia; Angela M Gronenborn; Danxia Ke; Gongpu Zhao; Peijun Zhang
Protease cleavage leads to formation of mature trimer interface in HIV-1 capsid.
PLoS pathogens 2012;8(8):e1002886.
2012: Ruifeng Yang; Jinwoo Ahn; In-Ja L Byeon; Angela M Gronenborn; Jens Meiler; Jonathan H Sheehan; Jiong Shi; Christopher Aiken
Second-site suppressors of HIV-1 capsid mutations: restoration of intracellular activities without correction of intrinsic capsid stability defects.
Retrovirology 2012;9():30.
2011: Guangjin Hou; Jinwoo Ahn; In-Ja L Byeon; Angela M Gronenborn; Tatyana Polenova
1H-13C/1H-15N heteronuclear dipolar recoupling by R-symmetry sequences under fast magic angle spinning for dynamics analysis of biological and organic solids.
Journal of the American Chemical Society 2011;133(46):18646-55.
2011: Xin Wang; Lingquan Deng; Angela M Gronenborn; Elena Matei; Olof Ramström; Mingdi Yan
Multivalent glyconanoparticles with enhanced affinity to the anti-viral lectin Cyanovirin-N.
Chemical communications (Cambridge, England) 2011;47(30):8620-2.
2011: Leonardus M I Koharudin; Angela M Gronenborn
Structural basis of the anti-HIV activity of the cyanobacterial Oscillatoria Agardhii agglutinin.
Structure (London, England : 1993) 2011;19(8):1170-81.
2011: Leonardus M I Koharudin; Arturo R Viscomi; Barbara Montanini; Michael J Kershaw; Nicholas J Talbot; Simone Ottonello; Angela M Gronenborn
Structure-function analysis of a CVNH-LysM lectin expressed during plant infection by the rice blast fungus Magnaporthe oryzae.
Structure (London, England : 1993) 2011;19(5):662-74.
2011: Jinwon Jung; In-Ja L Byeon; Jinwoo Ahn; Angela M Gronenborn
Structure, dynamics, and Hck interaction of full-length HIV-1 Nef.
Proteins 2011;79(5):1609-22.
2011: Elena Matei; John M Louis; JunGoo Jee; Angela M Gronenborn
NMR solution structure of a cyanovirin homolog from wheat head blight fungus.
Proteins 2011;79(5):1538-49.
2011: Guangjin Hou; Si Yan; Shangjin Sun; Yun Han; In-Ja L Byeon; Jinwoo Ahn; Jason Concel; Ago Samoson; Angela M Gronenborn; Tatyana Polenova
Spin diffusion driven by R-symmetry sequences: applications to homonuclear correlation spectroscopy in MAS NMR of biological and organic solids.
Journal of the American Chemical Society 2011;133(11):3943-53.
2011: Gongpu Zhao; Danxia Ke; Thomas Vu; Jinwoo Ahn; Vaibhav B Shah; Ruifeng Yang; Christopher Aiken; Lisa M Charlton; Angela M Gronenborn; Peijun Zhang
Rhesus TRIM5α disrupts the HIV-1 capsid at the inter-hexamer interfaces.
PLoS pathogens 2011;7(3):e1002009.
2011: Jinwoo Ahn; Zach Novince; Jason Concel; Chang-Hyeock Byeon; Alexander M Makhov; In-Ja L Byeon; Peijun Zhang; Angela M Gronenborn
The Cullin-RING E3 ubiquitin ligase CRL4-DCAF1 complex dimerizes via a short helical region in DCAF1.
Biochemistry 2011;50(8):1359-67.
2011: Leonardus M I Koharudin; William Furey; Angela M Gronenborn
Novel fold and carbohydrate specificity of the potent anti-HIV cyanobacterial lectin from Oscillatoria agardhii.
The Journal of biological chemistry 2011;286(2):1588-97.
2011: Khanh K Dao; Angel L Pey; Anja Underhaug Gjerde; Knut Teigen; In-Ja L Byeon; Stein Ove Døskeland; Angela M Gronenborn; Aurora Martinez
The regulatory subunit of PKA-I remains partially structured and undergoes β-aggregation upon thermal denaturation.
PloS one 2011;6(3):e17602.
2010: Guangjin Hou; Sivakumar Paramasivam; In-Ja L Byeon; Angela M Gronenborn; Tatyana Polenova
Determination of relative tensor orientations by γ-encoded chemical shift anisotropy/heteronuclear dipolar coupling 3D NMR spectroscopy in biological solids.
Physical chemistry chemical physics : PCCP 2010;12(45):14873-83.
2010: Jinwoo Ahn; Thomas Vu; Zach Novince; Jennifer Guerrero-Santoro; Vesna Rapic-Otrin; Angela M Gronenborn
HIV-1 Vpr loads uracil DNA glycosylase-2 onto DCAF1, a substrate recognition subunit of a cullin 4A-ring E3 ubiquitin ligase for proteasome-dependent degradation.
The Journal of biological chemistry 2010;285(48):37333-41.
2010: Joseph D Walsh; Katlyn Meier; Rieko Ishima; Angela M Gronenborn
NMR studies on domain diffusion and alignment in modular GB1 repeats.
Biophysical journal 2010;99(8):2636-46.
2010: Jimmy D Dikeakos; Katelyn M Atkins; Laurel Thomas; Lori Emert-Sedlak; In-Ja L Byeon; Jinwon Jung; Jinwoo Ahn; matthew d wortman; Ben Kukull; Masumichi Saito; Hirokazu Koizumi; Danielle M Williamson; Masateru Hiyoshi; Eric Barklis; Masafumi Takiguchi; Shinya Suzu; Angela M Gronenborn; Thomas E Smithgall; Gary Thomas
Small molecule inhibition of HIV-1-induced MHC-I down-regulation identifies a temporally regulated switch in Nef action.
Molecular biology of the cell 2010;21(19):3279-92.
2010: In-Ja L Byeon; Khanh K Dao; Jinwon Jung; Jeffrey Keen; Ingar Leiros; Stein O Døskeland; Aurora Martinez; Angela M Gronenborn
Allosteric communication between cAMP binding sites in the RI subunit of protein kinase A revealed by NMR.
The Journal of biological chemistry 2010;285(18):14062-70.
2010: Elena Matei; Andrew Zheng; William Furey; Jeremy Rose; Christopher Aiken; Angela M Gronenborn
Anti-HIV activity of defective cyanovirin-N mutants is restored by dimerization.
The Journal of biological chemistry 2010;285(17):13057-65.
2010: Leonardus M I Koharudin; Hao Liu; Roberto Di Maio; Ravindra B Kodali; Steven H Graham; Angela M Gronenborn
Cyclopentenone prostaglandin-induced unfolding and aggregation of the Parkinson disease-associated UCH-L1.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(15):6835-40.
2010: Jinwon Jung; In-Ja L Byeon; Jinwoo Ahn; Jason Concel; Angela M Gronenborn
1H, 15N and 13C assignments of the dimeric C-terminal domain of HIV-1 capsid protein.
Biomolecular NMR assignments 2010;4(1):21-3.
2010: Yun Han; Jinwoo Ahn; Jason Concel; In-Ja L Byeon; Angela M Gronenborn; Jun Yang; Tatyana Polenova
Solid-state NMR studies of HIV-1 capsid protein assemblies.
Journal of the American Chemical Society 2010;132(6):1976-87.
2010: Jinwoo Ahn; In-Ja L Byeon; Sanjeewa Dharmasena; Kelly Huber; Jason Concel; Angela M Gronenborn; Nicolas Sluis-Cremer
The RNA binding protein HuR does not interact directly with HIV-1 reverse transcriptase and does not affect reverse transcription in vitro.
Retrovirology 2010;7():40.
2009: Lin Liu; Leonardus M I Koharudin; Angela M Gronenborn; Ivet Bahar
A comparative analysis of the equilibrium dynamics of a designed protein inferred from NMR, X-ray, and computations.
Proteins 2009;77(4):927-39.
2009: Leonardus M I Koharudin; William Furey; Angela M Gronenborn
A designed chimeric cyanovirin-N homolog lectin: structure and molecular basis of sucrose binding.
Proteins 2009;77(4):904-15.
2009: Yasumasa Iwatani; Denise S B Chan; Lin Liu; Hiroaki Yoshii; Junko Shibata; Naoki Yamamoto; Judith G Levin; Angela M Gronenborn; Wataru Sugiura
HIV-1 Vif-mediated ubiquitination/degradation of APOBEC3G involves four critical lysine residues in its C-terminal domain.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(46):19539-44.
2009: In-Ja L Byeon; Xin Meng; Jinwon Jung; Gongpu Zhao; Ruifeng Yang; Jinwoo Ahn; Jiong Shi; Jason Concel; Christopher Aiken; Peijun Zhang; Angela M Gronenborn
Structural convergence between Cryo-EM and NMR reveals intersubunit interactions critical for HIV-1 capsid function.
Cell 2009;139(4):780-90.
2009: Leonardus M I Koharudin; William Furey; Hao Liu; Yong-Jian Liu; Angela M Gronenborn
The phox domain of sorting nexin 5 lacks phosphatidylinositol 3-phosphate (PtdIns(3)P) specificity and preferentially binds to phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2).
The Journal of biological chemistry 2009;284(35):23697-707.
2009: Jinbu Wang; Xiaobing Zuo; Ping Yu; In-Ja L Byeon; Jinwon Jung; Xiaoxia Wang; Marzena Dyba; Soenke Seifert; Charles D Schwieters; Jun Qin; Angela M Gronenborn; Yun-Xing Wang
Determination of multicomponent protein structures in solution using global orientation and shape restraints.
Journal of the American Chemical Society 2009;131(30):10507-15.
2009: Jinwoo Ahn; In-Ja L Byeon; Chang-Hyeock Byeon; Angela M Gronenborn
Insight into the structural basis of pro- and antiapoptotic p53 modulation by ASPP proteins.
The Journal of biological chemistry 2009;284(20):13812-22.
2009: Jinwon Jung; In-Ja L Byeon; Yongting Wang; Jonathan King; Angela M Gronenborn
The structure of the cataract-causing P23T mutant of human gammaD-crystallin exhibits distinctive local conformational and dynamic changes.
Biochemistry 2009;48(12):2597-609.
2009: Angela M Gronenborn
Protein acrobatics in pairs--dimerization via domain swapping.
Current opinion in structural biology 2009;19(1):39-49.
2008: Elena Matei; William Furey; Angela M Gronenborn
Solution and crystal structures of a sugar binding site mutant of cyanovirin-N: no evidence of domain swapping.
Structure (London, England : 1993) 2008;16(8):1183-94.
2008: JunGoo Jee; In-Ja L Byeon; John M Louis; Angela M Gronenborn
The point mutation A34F causes dimerization of GB1.
Proteins 2008;71(3):1420-31.
2008: Jungoo Jee; Rieko Ishima; Angela M Gronenborn
Characterization of specific protein association by 15N CPMG relaxation dispersion NMR: the GB1(A34F) monomer-dimer equilibrium.
The journal of physical chemistry. B 2008;112(19):6008-12.
2008: Leonardus M I Koharudin; Arturo R Viscomi; Jun-Goo Jee; Simone Ottonello; Angela M Gronenborn
The evolutionarily conserved family of cyanovirin-N homologs: structures and carbohydrate specificity.
Structure (London, England : 1993) 2008;16(4):570-84.
2008: Corine Sandström; Birgit Hakkarainen; Elena Matei; Anja Glinchert; Martina Lahmann; Stefan Oscarson; Lennart Kenne; Angela M Gronenborn
Atomic mapping of the sugar interactions in one-site and two-site mutants of cyanovirin-N by NMR spectroscopy.
Biochemistry 2008;47(12):3625-35.
2007: Astghik A Shahkhatuni; Aleksan Shahkhatuni; Henry A Panosyan; Aleksandr B Sahakyan; In-Ja L Byeon; Angela M Gronenborn
Assessment of solvent effects: do weak alignment media affect the structure of the solute?
Magnetic resonance in chemistry : MRC 2007;45(7):557-63.
2007: Lee-Wei Yang; Eran Eyal; Chakra Chennubhotla; Jun-Goo Jee; Angela M Gronenborn; Ivet Bahar
Insights into equilibrium dynamics of proteins from comparison of NMR and X-ray data with computational predictions.
Structure (London, England : 1993) 2007;15(6):741-9.
2007: Susana Vega-Rocha; Angela M Gronenborn; Bruno Gronenborn; Ramón Campos-Olivas
1H, 13C, and 15N NMR assignment of the master Rep protein nuclease domain from the nanovirus FBNYV.
Journal of biomolecular NMR 2007;38(2):169.
2007: Susana Vega-Rocha; Bruno Gronenborn; Angela M Gronenborn; Ramón Campos-Olivas
Solution structure of the endonuclease domain from the master replication initiator protein of the nanovirus faba bean necrotic yellows virus and comparison with the corresponding geminivirus and circovirus structures.
Biochemistry 2007;46(21):6201-12.
2007: Susana Vega-Rocha; In-Ja L Byeon; Bruno Gronenborn; Angela M Gronenborn; Ramón Campos-Olivas
Solution structure, divalent metal and DNA binding of the endonuclease domain from the replication initiation protein from porcine circovirus 2.
Journal of molecular biology 2007;367(2):473-87.
2007: Dmitri N Ermolenko; Bindi Dangi; Anzor Gvritishvili; Angela M Gronenborn; George I Makhatadze
Elimination of the C-cap in ubiquitin - structure, dynamics and thermodynamic consequences.
Biophysical chemistry 2007;126(1-3):25-35.
2007: Yasumasa Iwatani; Denise S B Chan; F Wang; Kristen Stewart Maynard; Wataru Sugiura; Angela M Gronenborn; Ioulia Rouzina; Mark C Williams; Karin Musier-Forsyth; Judith G Levin
Deaminase-independent inhibition of HIV-1 reverse transcription by APOBEC3G.
Nucleic acids research 2007;35(21):7096-108.
2006: Dmitri Toptygin; Angela M Gronenborn; Ludwig Brand
Nanosecond relaxation dynamics of protein GB1 identified by the time-dependent red shift in the fluorescence of tryptophan and 5-fluorotryptophan.
The journal of physical chemistry. B 2006;110(51):26292-302.
2006: Laura G Barrientos; Elena Matei; Fátima Lasala; Rafael Delgado; Angela M Gronenborn
Dissecting carbohydrate-Cyanovirin-N binding by structure-guided mutagenesis: functional implications for viral entry inhibition.
Protein engineering, design & selection : PEDS 2006;19(12):525-35.
2005: Sergey Zubkov; Angela M Gronenborn; In-Ja L Byeon; Smita Mohanty
Structural consequences of the pH-induced conformational switch in A.polyphemus pheromone-binding protein: mechanisms of ligand release.
Journal of molecular biology 2005;354(5):1081-90.
2005: In-Ja L Byeon; Hongyuan Li; Haiyan Song; Angela M Gronenborn; Ming-Daw Tsai
Sequential phosphorylation and multisite interactions characterize specific target recognition by the FHA domain of Ki67.
Nature structural & molecular biology 2005;12(11):987-93.
2005: Shane L Mangold; Joel R Morgan; Gregory C Strohmeyer; Angela M Gronenborn; Mary J Cloninger
Cyanovirin-N binding to Manalpha1-2Man functionalized dendrimers.
Organic & biomolecular chemistry 2005;3(12):2354-8.
2005: John M Louis; In-Ja L Byeon; Ulrich Baxa; Angela M Gronenborn
The GB1 amyloid fibril: recruitment of the peripheral beta-strands of the domain swapped dimer into the polymeric interface.
Journal of molecular biology 2005;348(3):687-98.
2005: Laura G Barrientos; Angela M Gronenborn
The highly specific carbohydrate-binding protein cyanovirin-N: structure, anti-HIV/Ebola activity and possibilities for therapy.
Mini reviews in medicinal chemistry 2005;5(1):21-31.
2004: Corine Sandström; Olivier Berteau; Emiliano Gemma; Stefan Oscarson; Lennart Kenne; Angela M Gronenborn
Atomic mapping of the interactions between the antiviral agent cyanovirin-N and oligomannosides by saturation-transfer difference NMR.
Biochemistry 2004;43(44):13926-31.
2004: Laura G Barrientos; Fátima Lasala; Rafael Delgado; Anthony Sanchez; Angela M Gronenborn
Flipping the switch from monomeric to dimeric CV-N has little effect on antiviral activity.
Structure (London, England : 1993) 2004;12(10):1799-807.
2004: Bindi Dangi; Angela M Gronenborn; Judah L Rosner; Robert G Martin
Versatility of the carboxy-terminal domain of the alpha subunit of RNA polymerase in transcriptional activation: use of the DNA contact site as a protein contact site for MarA.
Molecular microbiology 2004;54(1):45-59.
2004: In-Ja L Byeon; John M Louis; Angela M Gronenborn
A captured folding intermediate involved in dimerization and domain-swapping of GB1.
Journal of molecular biology 2004;340(3):615-25.
2004: Keyang Ding; Angela M Gronenborn
Protein Backbone 1H(N)-13Calpha and 15N-13Calpha residual dipolar and J couplings: new constraints for NMR structure determination.
Journal of the American Chemical Society 2004;126(20):6232-3.
2004: Keyang Ding; Angela M Gronenborn
Sensitivity-enhanced IPAP experiments for measuring one-bond 13C'-13Calpha and 13Calpha-1Halpha residual dipolar couplings in proteins.
Journal of magnetic resonance (San Diego, Calif. : 1997) 2004;167(2):253-8.
2004: Smita Mohanty; Sergey Zubkov; Angela M Gronenborn
The solution NMR structure of Antheraea polyphemus PBP provides new insight into pheromone recognition by pheromone-binding proteins.
Journal of molecular biology 2004;337(2):443-51.
2004: Jeffrey McKinney; Per M Knappskog; Jacinto Pereira; Trude Ekern; Karen Toska; Baukje B Kuitert; David Levine; Angela M Gronenborn; Aurora Martinez; Jan Haavik
Expression and purification of human tryptophan hydroxylase from Escherichia coli and Pichia pastoris.
Protein expression and purification 2004;33(2):185-94.
2004: Keyang Ding; John M Louis; Angela M Gronenborn
Insights into conformation and dynamics of protein GB1 during folding and unfolding by NMR.
Journal of molecular biology 2004;335(5):1299-307.
2003: Rieko Ishima; Dennis A Torchia; Shannon M Lynch; Angela M Gronenborn; John M Louis
Solution structure of the mature HIV-1 protease monomer: insight into the tertiary fold and stability of a precursor.
The Journal of biological chemistry 2003;278(44):43311-9.
2003: In-Ja L Byeon; John M Louis; Angela M Gronenborn
A protein contortionist: core mutations of GB1 that induce dimerization and domain swapping.
Journal of molecular biology 2003;333(1):141-52.
2003: Anatoliy Dobrodumov; Angela M Gronenborn
Filtering and selection of structural models: combining docking and NMR.
Proteins 2003;53(1):18-32.
2003: Keyang Ding; Angela M Gronenborn
Simultaneous and accurate determination of one-bond (15)N-(13)C' and two-bond (1)H(N)--(13)C' dipolar couplings.
Journal of the American Chemical Society 2003;125(38):11504-5.
2003: Keyang Ding; Angela M Gronenborn
Sensitivity-enhanced 2D IPAP, TROSY-anti-TROSY, and E.COSY experiments: alternatives for measuring dipolar 15N-1HN couplings.
Journal of magnetic resonance (San Diego, Calif. : 1997) 2003;163(2):208-14.
2003: Etsuko Katoh; John M Louis; Toshimasa Yamazaki; Angela M Gronenborn; Dennis A Torchia; Rieko Ishima
A solution NMR study of the binding kinetics and the internal dynamics of an HIV-1 protease-substrate complex.
Protein science : a publication of the Protein Society 2003;12(7):1376-85.
2003: Angela M Gronenborn
Rapid screening of E. coli extracts by heteronuclear NMR.
Current protocols in protein science / editorial board, John E. Coligan ... [et al.] 2003;Chapter 7():Unit 7.11.
2003: Laura G Barrientos; Barry R O'Keefe; Mike Bray; Anthony Sanchez; Angela M Gronenborn; Michael R Boyd
Cyanovirin-N binds to the viral surface glycoprotein, GP1,2 and inhibits infectivity of Ebola virus.
Antiviral research 2003;58(1):47-56.
2003: John M Louis; Rieko Ishima; Issa Nesheiwat; Lewis K Pannell; Shannon M Lynch; Dennis A Torchia; Angela M Gronenborn
Revisiting monomeric HIV-1 protease. Characterization and redesign for improved properties.
The Journal of biological chemistry 2003;278(8):6085-92.
2003: Laura G Barrientos; John M Louis; Daniel M Ratner; Peter H Seeberger; Angela M Gronenborn
Solution structure of a circular-permuted variant of the potent HIV-inactivating protein cyanovirin-N: structural basis for protein stability and oligosaccharide interaction.
Journal of molecular biology 2003;325(1):211-23.
2002: Laura G Barrientos; Angela M Gronenborn
The domain-swapped dimer of cyanovirin-N contains two sets of oligosaccharide binding sites in solution.
Biochemical and biophysical research communications 2002;298(4):598-602.
2002: Olga Tcherkasskaya; Angela M Gronenborn; Leonid Klushin
Excluded volume effect within the continuous model for the fluorescence energy transfer.
Biophysical journal 2002;83(5):2826-34.
2002: M Kirsten Frank; Fred Dyda; Anatoliy Dobrodumov; Angela M Gronenborn
Core mutations switch monomeric protein GB1 into an intertwined tetramer.
Nature structural biology 2002;9(11):877-85.
2002: Shilpa R Shenoy; Laura G Barrientos; Daniel M Ratner; Barry R O'Keefe; Peter H Seeberger; Angela M Gronenborn; Michael R Boyd
Multisite and multivalent binding between cyanovirin-N and branched oligomannosides: calorimetric and NMR characterization.
Chemistry & biology 2002;9(10):1109-18.
2002: Toshiyuki Mori; Laura G Barrientos; Zhaozhong Han; Angela M Gronenborn; Jim A Turpin; Michael R Boyd
Functional homologs of cyanovirin-N amenable to mass production in prokaryotic and eukaryotic hosts.
Protein expression and purification 2002;26(1):42-9.
2002: Dmitri N Ermolenko; Susan T Thomas; Aurora Rajeev; Angela M Gronenborn; George I Makhatadze
Hydrophobic interactions at the Ccap position of the C-capping motif of alpha-helices.
Journal of molecular biology 2002;322(1):123-35.
2002: Angela M Gronenborn
The importance of being ordered: improving NMR structures using residual dipolar couplings.
Comptes rendus biologies 2002;325(9):957-66.
2002: Ramón Campos-Olivas; John M Louis; Danielle Clérot; Bruno Gronenborn; Angela M Gronenborn
1H, 13C, and 15N assignment of the N-terminal, catalytic domain of the replication initiation protein from the geminivirus TYLCV.
Journal of biomolecular NMR 2002;24(1):73-4.
2002: Keyang Ding; Angela M Gronenborn
Sensitivity-enhanced E.COSY-type HSQC experiments for accurate measurements of one-bond 15N-1H(N) and 15N-13C' and two-bond 13C'-1H(N) residual dipolar couplings in proteins.
Journal of magnetic resonance (San Diego, Calif. : 1997) 2002;158(1-2):173-7.
2002: Ramón Campos-Olivas; John M Louis; Danielle Clerot; Bruno Gronenborn; Angela M Gronenborn
The structure of a replication initiator unites diverse aspects of nucleic acid metabolism.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(16):10310-5.
2002: Bindi Dangi; Anatoliy Dobrodumov; John M Louis; Angela M Gronenborn
Solution structure and dynamics of the human-Escherichia coli thioredoxin chimera: insights into thermodynamic stability.
Biochemistry 2002;41(30):9376-88.
2002: Keyang Ding; Angela M Gronenborn
Novel 2D triple-resonance NMR experiments for sequential resonance assignments of proteins.
Journal of magnetic resonance (San Diego, Calif. : 1997) 2002;156(2):262-8.
2002: Laura G Barrientos; John M Louis; Istvan Botos; Toshiyuki Mori; Zhaozhong Han; Barry R O'Keefe; Michael R Boyd; Alexander Wlodawer; Angela M Gronenborn
The domain-swapped dimer of cyanovirin-N is in a metastable folded state: reconciliation of X-ray and NMR structures.
Structure (London, England : 1993) 2002;10(5):673-86.
2002: Ramón Campos-Olivas; Rehan Aziz; Gregory L Helms; Jeremy N S Evans; Angela M Gronenborn
Placement of 19F into the center of GB1: effects on structure and stability.
FEBS letters 2002;517(1-3):55-60.
2002: Judah L Rosner; Bindi Dangi; Angela M Gronenborn; Robert G Martin
Posttranscriptional activation of the transcriptional activator Rob by dipyridyl in Escherichia coli.
Journal of bacteriology 2002;184(5):1407-16.
2002: Laura G Barrientos; John M Louis; Jason Hung; Trent H Smith; Barry R O'Keefe; Roberta S Gardella; Toshiyuki Mori; Michael R Boyd; Angela M Gronenborn
Design and initial characterization of a circular permuted variant of the potent HIV-inactivating protein cyanovirin-N.
Proteins 2002;46(2):153-60.
2002: Olga Tcherkasskaya; Leonid Klushin; Angela M Gronenborn
Effective lattice behavior of fluorescence energy transfer at lamellar macromolecular interfaces.
Biophysical journal 2002;82(2):988-95.
2001: Rieko Ishima; R Ghirlando; J Tözsér; Angela M Gronenborn; Dennis A Torchia; John M Louis
Folded monomer of HIV-1 protease.
The Journal of biological chemistry 2001;276(52):49110-6.
2001: Bindi Dangi; P Pelupessey; Robert G Martin; Judah L Rosner; John M Louis; Angela M Gronenborn
Structure and dynamics of MarA-DNA complexes: an NMR investigation.
Journal of molecular biology 2001;314(1):113-27.
2001: John M Louis; RE Georgescu; María Luisa Tasayco; O Tcherkasskaya; Angela M Gronenborn
Probing the structure and stability of a hybrid protein: the human-E. coli thioredoxin chimera.
Biochemistry 2001;40(37):11184-92.
2001: Ramón Campos-Olivas; I Hörr; C Bormann; Günther Jung; Angela M Gronenborn
Solution structure, backbone dynamics and chitin binding of the anti-fungal protein from Streptomyces tendae TU901.
Journal of molecular biology 2001;308(4):765-82.
2001: Laura G Barrientos; Ramón Campos-Olivas; John M Louis; András Fiser; Andrej Sali; Angela M Gronenborn
1H, 13C, 15N resonance assignments and fold verification of a circular permuted variant of the potent HIV-inactivating protein cyanovirin-N.
Journal of biomolecular NMR 2001;19(3):289-90.
2001: Laura G Barrientos; John M Louis; Angela M Gronenborn
Characterization of the cholesteric phase of filamentous bacteriophage fd for molecular alignment.
Journal of magnetic resonance (San Diego, Calif. : 1997) 2001;149(1):154-8.
2000: Olga Tcherkasskaya; V E Bychkova; Vladimir Uversky; Angela M Gronenborn
Multisite fluorescence in proteins with multiple tryptophan residues. Apomyoglobin natural variants and site-directed mutants.
The Journal of biological chemistry 2000;275(46):36285-94.
2000: Olga Tcherkasskaya; Jay R Knutson; S A Bowley; M K Frank; Angela M Gronenborn
Nanosecond dynamics of the single tryptophan reveals multi-state equilibrium unfolding of protein GB1.
Biochemistry 2000;39(37):11216-26.
2000: Laura G Barrientos; C Dolan; Angela M Gronenborn
Characterization of surfactant liquid crystal phases suitable for molecular alignment and measurement of dipolar couplings.
Journal of biomolecular NMR 2000;16(4):329-37.
2000: C Castagné; Elizabeth C Murphy; Angela M Gronenborn; Muriel DELEPIERRE
31P NMR analysis of the DNA conformation induced by protein binding SRY/DNA complexes.
European journal of biochemistry / FEBS 2000;267(4):1223-9.
2000: John M Louis; Irene T Weber; József Tözsér; G Marius Clore; Angela M Gronenborn
HIV-1 protease: maturation, enzyme specificity, and drug resistance.
Advances in pharmacology (San Diego, Calif.) 2000;49():111-46.
1999: Michael Caffrey; J Kaufman; S Stahl; Paul T Wingfield; Angela M Gronenborn; G Marius Clore
Monomer-trimer equilibrium of the ectodomain of SIV gp41: insight into the mechanism of peptide inhibition of HIV infection.
Protein science : a publication of the Protein Society 1999;8(9):1904-7.
1999: John M Louis; G Marius Clore; Angela M Gronenborn
Autoprocessing of HIV-1 protease is tightly coupled to protein folding.
Nature structural biology 1999;6(9):868-75.
1999: Daniel S Garrett; Yeong-Jae Seok; Alan Peterkofsky; Angela M Gronenborn; G Marius Clore
Solution structure of the 40,000 Mr phosphoryl transfer complex between the N-terminal domain of enzyme I and HPr.
Nature structural biology 1999;6(2):166-73.
1999: Angela M Gronenborn; G Marius Clore; John M Louis; Paul T Wingfield
Is human thioredoxin monomeric or dimeric?
Protein science : a publication of the Protein Society 1999;8(2):426-9.
1998: Michael Caffrey; J Kaufman; Stephen J Stahl; Paul T Wingfield; Angela M Gronenborn; G Marius Clore
3D NMR experiments for measuring 15N relaxation data of large proteins: application to the 44 kDa ectodomain of SIV gp41.
Journal of magnetic resonance (San Diego, Calif. : 1997) 1998;135(2):368-72.
1998: Mengli Cai; Y Huang; Michael Caffrey; R Zheng; Robert Craigie; G Marius Clore; Angela M Gronenborn
Solution structure of the His12 --> Cys mutant of the N-terminal zinc binding domain of HIV-1 integrase complexed to cadmium.
Protein science : a publication of the Protein Society 1998;7(12):2669-74.
1998: G Marius Clore; Angela M Gronenborn
NMR structure determination of proteins and protein complexes larger than 20 kDa.
Current opinion in chemical biology 1998;2(5):564-70.
1998: Mengli Cai; Y Huang; R Zheng; SQ Wei; Rodolfo Ghirlando; MS Lee; Robert Craigie; Angela M Gronenborn; G Marius Clore
Solution structure of the cellular factor BAF responsible for protecting retroviral DNA from autointegration.
Nature structural biology 1998;5(10):903-9.
1998: G Marius Clore; Elizabeth C Murphy; Angela M Gronenborn; Adriaan Bax
Determination of three-bond 1H3'-31P couplings in nucleic acids and protein-nucleic acid complexes by quantitative J correlation spectroscopy.
Journal of magnetic resonance (San Diego, Calif. : 1997) 1998;134(1):164-7.
1998: Michael Caffrey; Mengli Cai; J Kaufman; Stephen J Stahl; Paul T Wingfield; D G Covell; Angela M Gronenborn; G Marius Clore
Three-dimensional solution structure of the 44 kDa ectodomain of SIV gp41.
The EMBO journal 1998;17(16):4572-84.
1998: Carole A Bewley; K R Gustafson; M R Boyd; D G Covell; Adriaan Bax; G Marius Clore; Angela M Gronenborn
Solution structure of cyanovirin-N, a potent HIV-inactivating protein.
Nature structural biology 1998;5(7):571-8.
1998: G Marius Clore; Angela M Gronenborn; Adriaan Bax
A robust method for determining the magnitude of the fully asymmetric alignment tensor of oriented macromolecules in the absence of structural information.
Journal of magnetic resonance (San Diego, Calif. : 1997) 1998;133(1):216-21.
1998: G Marius Clore; Angela M Gronenborn
New methods of structure refinement for macromolecular structure determination by NMR.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(11):5891-8.
1998: M R Starich; M Wikström; S Schumacher; H N Arst; Angela M Gronenborn; G Marius Clore
The solution structure of the Leu22-->Val mutant AREA DNA binding domain complexed with a TGATAG core element defines a role for hydrophobic packing in the determination of specificity.
Journal of molecular biology 1998;277(3):621-34.
1998: M R Starich; M Wikström; H N Arst; G Marius Clore; Angela M Gronenborn
The solution structure of a fungal AREA protein-DNA complex: an alternative binding mode for the basic carboxyl tail of GATA factors.
Journal of molecular biology 1998;277(3):605-20.
1998: Daniel S Garrett; Yeong-Jae Seok; Alan Peterkofsky; G Marius Clore; Angela M Gronenborn
Tautomeric state and pKa of the phosphorylated active site histidine in the N-terminal domain of enzyme I of the Escherichia coli phosphoenolpyruvate:sugar phosphotransferase system.
Protein science : a publication of the Protein Society 1998;7(3):789-93.
1998: G Marius Clore; Angela M Gronenborn; Nico Tjandra
Direct structure refinement against residual dipolar couplings in the presence of rhombicity of unknown magnitude.
Journal of magnetic resonance (San Diego, Calif. : 1997) 1998;131(1):159-62.
1998: John M Louis; Robert G Martin; G Marius Clore; Angela M Gronenborn
Preparation of uniformly isotope-labeled DNA oligonucleotides for NMR spectroscopy.
The Journal of biological chemistry 1998;273(4):2374-8.
1998: Carole A Bewley; Angela M Gronenborn; G Marius Clore
Minor groove-binding architectural proteins: structure, function, and DNA recognition.
Annual review of biophysics and biomolecular structure 1998;27():105-31.
1998: Mengli Cai; Y Huang; K Sakaguchi; G Marius Clore; Angela M Gronenborn; Robert Craigie
An efficient and cost-effective isotope labeling protocol for proteins expressed in Escherichia coli.
Journal of biomolecular NMR 1998;11(1):97-102.
1997: S Schumacher; R T Clubb; Mengli Cai; Kiyoshi Mizuuchi; G Marius Clore; Angela M Gronenborn
Solution structure of the Mu end DNA-binding ibeta subdomain of phage Mu transposase: modular DNA recognition by two tethered domains.
The EMBO journal 1997;16(24):7532-41.
1997: J R Huth; Carole A Bewley; B M Jackson; A G Hinnebusch; G Marius Clore; Angela M Gronenborn
Design of an expression system for detecting folded protein domains and mapping macromolecular interactions by NMR.
Protein science : a publication of the Protein Society 1997;6(11):2359-64.
1997: R T Clubb; S Schumacher; Kiyoshi Mizuuchi; Angela M Gronenborn; G Marius Clore
Solution structure of the I gamma subdomain of the Mu end DNA-binding domain of phage Mu transposase.
Journal of molecular biology 1997;273(1):19-25.
1997: G Marius Clore; Angela M Gronenborn
NMR structures of proteins and protein complexes beyond 20,000 M(r).
Nature structural biology 1997;4 Suppl():849-53.
1997: Michael Caffrey; Mengli Cai; J Kaufman; Stephen J Stahl; Paul T Wingfield; Angela M Gronenborn; G Marius Clore
Determination of the secondary structure and global topology of the 44 kDa ectodomain of gp41 of the simian immunodeficiency virus by multidimensional nuclear magnetic resonance spectroscopy.
Journal of molecular biology 1997;271(5):819-26.
1997: Nico Tjandra; James G. Omichinski; Angela M Gronenborn; G Marius Clore; Adriaan Bax
Use of dipolar 1H-15N and 1H-13C couplings in the structure determination of magnetically oriented macromolecules in solution.
Nature structural biology 1997;4(9):732-8.
1997: J R Huth; Carole A Bewley; MS Nissen; Jeremy N S Evans; Raymond Reeves; Angela M Gronenborn; G Marius Clore
The solution structure of an HMG-I(Y)-DNA complex defines a new architectural minor groove binding motif.
Nature structural biology 1997;4(8):657-65.
1997: Mengli Cai; R Zheng; Michael Caffrey; Robert Craigie; G Marius Clore; Angela M Gronenborn
Solution structure of the N-terminal zinc binding domain of HIV-1 integrase.
Nature structural biology 1997;4(7):567-77.
1997: Nico Tjandra; Daniel S Garrett; Angela M Gronenborn; Adriaan Bax; G Marius Clore
Defining long range order in NMR structure determination from the dependence of heteronuclear relaxation times on rotational diffusion anisotropy.
Nature structural biology 1997;4(6):443-9.
1997: Paolo V Pedone; James G. Omichinski; P Nony; Cecelia D Trainor; Angela M Gronenborn; G Marius Clore; Gary Felsenfeld
The N-terminal fingers of chicken GATA-2 and GATA-3 are independent sequence-specific DNA binding domains.
The EMBO journal 1997;16(10):2874-82.
1997: Daniel S Garrett; Yeong-Jae Seok; Alan Peterkofsky; G Marius Clore; Angela M Gronenborn
Identification by NMR of the binding surface for the histidine-containing phosphocarrier protein HPr on the N-terminal domain of enzyme I of the Escherichia coli phosphotransferase system.
Biochemistry 1997;36(15):4393-8.
1997: Daniel S Garrett; Yeong-Jae Seok; D I Liao; Alan Peterkofsky; Angela M Gronenborn; G Marius Clore
Solution structure of the 30 kDa N-terminal domain of enzyme I of the Escherichia coli phosphoenolpyruvate:sugar phosphotransferase system by multidimensional NMR.
Biochemistry 1997;36(9):2517-30.
1997: John Kuszewski; Angela M Gronenborn; G Marius Clore
Improvements and extensions in the conformational database potential for the refinement of NMR and X-ray structures of proteins and nucleic acids.
Journal of magnetic resonance (San Diego, Calif. : 1997) 1997;125(1):171-7.
1997: James G. Omichinski; Paolo V Pedone; Gary Felsenfeld; Angela M Gronenborn; G Marius Clore
The solution structure of a specific GAGA factor-DNA complex reveals a modular binding mode.
Nature structural biology 1997;4(2):122-32.
1997: G Marius Clore; Angela M Gronenborn
Dissecting intrinsic chaperonin activity.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(1):7-8.
1996: Angela M Gronenborn; M K Frank; G Marius Clore
Core mutants of the immunoglobulin binding domain of streptococcal protein G: stability and structural integrity.
FEBS letters 1996;398(2-3):312-6.
1996: Milton H Werner; J R Huth; Angela M Gronenborn; G Marius Clore
Molecular determinants of mammmalian sex.
Trends in biochemical sciences 1996;21(8):302-8.
1996: J Kuszewski; Angela M Gronenborn; G Marius Clore
A potential involving multiple proton chemical-shift restraints for nonstereospecifically assigned methyl and methylene protons.
Journal of magnetic resonance. Series B 1996;112(1):79-81.
1996: J Kuszewski; Angela M Gronenborn; G Marius Clore
Improving the quality of NMR and crystallographic protein structures by means of a conformational database potential derived from structure databases.
Protein science : a publication of the Protein Society 1996;5(6):1067-80.
1996: J Qin; G Marius Clore; W P Kennedy; J Kuszewski; Angela M Gronenborn
The solution structure of human thioredoxin complexed with its target from Ref-1 reveals peptide chain reversal.
Structure (London, England : 1993) 1996;4(5):613-20.
1996: C D Trainor; James G. Omichinski; T L Vandergon; Angela M Gronenborn; G Marius Clore; Gary Felsenfeld
A palindromic regulatory site within vertebrate GATA-1 promoters requires both zinc fingers of the GATA-1 DNA-binding domain for high-affinity interaction.
Molecular and cellular biology 1996;16(5):2238-47.
1996: Paolo V Pedone; R Ghirlando; G Marius Clore; Angela M Gronenborn; Gary Felsenfeld; James G. Omichinski
The single Cys2-His2 zinc finger domain of the GAGA protein flanked by basic residues is sufficient for high-affinity specific DNA binding.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(7):2822-6.
1996: Stephan Grzesiek; Adriaan Bax; G Marius Clore; Angela M Gronenborn; Jin-Shan Hu; J Kaufman; I Palmer; Stephen J Stahl; Paul T Wingfield
The solution structure of HIV-1 Nef reveals an unexpected fold and permits delineation of the binding surface for the SH3 domain of Hck tyrosine protein kinase.
Nature structural biology 1996;3(4):340-5.
1996: Milton H Werner; Angela M Gronenborn; G Marius Clore
Intercalation, DNA kinking, and the control of transcription.
Science (New York, N.Y.) 1996;271(5250):778-84.
1996: R T Clubb; M Mizuuchi; J R Huth; James G. Omichinski; H Savilahti; Kiyoshi Mizuuchi; G Marius Clore; Angela M Gronenborn
The wing of the enhancer-binding domain of Mu phage transposase is flexible and is essential for efficient transposition.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(3):1146-50.
1996: J Qin; G Marius Clore; Angela M Gronenborn
Ionization equilibria for side-chain carboxyl groups in oxidized and reduced human thioredoxin and in the complex with its target peptide from the transcription factor NF kappa B.
Biochemistry 1996;35(1):7-13.
1996: Angela M Gronenborn; G Marius Clore
Rapid screening for structural integrity of expressed proteins by heteronuclear NMR spectroscopy.
Protein science : a publication of the Protein Society 1996;5(1):174-7.
1995: M K Frank; G Marius Clore; Angela M Gronenborn
Structural and dynamic characterization of the urea denatured state of the immunoglobulin binding domain of streptococcal protein G by multidimensional heteronuclear NMR spectroscopy.
Protein science : a publication of the Protein Society 1995;4(12):2605-15.
1995: Milton H Werner; M Clore; C L Fisher; Robert J Fisher; Loc Ba Trinh; Joseph Shiloach; Angela M Gronenborn
The solution structure of the human ETS1-DNA complex reveals a novel mode of binding and true side chain intercalation.
Cell 1995;83(5):761-71.
1995: T E Strzelecka; G Marius Clore; Angela M Gronenborn
The solution structure of the Mu Ner protein reveals a helix-turn-helix DNA recognition motif.
Structure (London, England : 1993) 1995;3(10):1087-95.
1995: Milton H Werner; M E Bianchi; Angela M Gronenborn; G Marius Clore
NMR spectroscopic analysis of the DNA conformation induced by the human testis determining factor SRY.
Biochemistry 1995;34(37):11998-2004.
1995: P J Lodi; J A Ernst; J Kuszewski; Alison Burgess Hickman; Alan Engelman; Robert Craigie; G Marius Clore; Angela M Gronenborn
Solution structure of the DNA binding domain of HIV-1 integrase.
Biochemistry 1995;34(31):9826-33.
1995: Milton H Werner; J R Huth; Angela M Gronenborn; G Marius Clore
Molecular basis of human 46X,Y sex reversal revealed from the three-dimensional solution structure of the human SRY-DNA complex.
Cell 1995;81(5):705-14.
1995: J Kuszewski; Angela M Gronenborn; G Marius Clore
The impact of direct refinement against proton chemical shifts on protein structure determination by NMR.
Journal of magnetic resonance. Series B 1995;107(3):293-7.
1995: R T Clubb; James G. Omichinski; K Sakaguchi; Ettore Appella; Angela M Gronenborn; G Marius Clore
Backbone dynamics of the oligomerization domain of p53 determined from 15N NMR relaxation measurements.
Protein science : a publication of the Protein Society 1995;4(5):855-62.
1995: G Marius Clore; J Ernst; R Clubb; James G. Omichinski; W M Kennedy; K Sakaguchi; Ettore Appella; Angela M Gronenborn
Refined solution structure of the oligomerization domain of the tumour suppressor p53.
Nature structural biology 1995;2(4):321-33.
1995: J A Ernst; R T Clubb; Huan-Xiang Zhou; Angela M Gronenborn; G Marius Clore
Demonstration of positionally disordered water within a protein hydrophobic cavity by NMR.
Science (New York, N.Y.) 1995;267(5205):1813-7.
1995: J Qin; G Marius Clore; W M Kennedy; J R Huth; Angela M Gronenborn
Solution structure of human thioredoxin in a mixed disulfide intermediate complex with its target peptide from the transcription factor NF kappa B.
Structure (London, England : 1993) 1995;3(3):289-97.
1995: G Marius Clore; James G. Omichinski; Kazuyasu Sakaguchi; N Zambrano; H Sakamoto; Ettore Appella; Angela M Gronenborn
Interhelical angles in the solution structure of the oligomerization domain of p53: correction.
Science (New York, N.Y.) 1995;267(5203):1515-6.
1995: T E Strzelecka; Jeffrey J Hayes; G Marius Clore; Angela M Gronenborn
DNA binding specificity of the Mu Ner protein.
Biochemistry 1995;34(9):2946-55.
1995: J Kuszewski; J Qin; Angela M Gronenborn; G Marius Clore
The impact of direct refinement against 13C alpha and 13C beta chemical shifts on protein structure determination by NMR.
Journal of magnetic resonance. Series B 1995;106(1):92-6.
1995: G Marius Clore; Angela M Gronenborn
Three-dimensional structures of alpha and beta chemokines.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1995;9(1):57-62.
1994: R T Clubb; James G. Omichinski; H Savilahti; Kiyoshi Mizuuchi; Angela M Gronenborn; G Marius Clore
A novel class of winged helix-turn-helix protein: the DNA-binding domain of Mu transposase.
Structure (London, England : 1993) 1994;2(11):1041-8.
1994: J Kuszewski; G Marius Clore; Angela M Gronenborn
Fast folding of a prototypic polypeptide: the immunoglobulin binding domain of streptococcal protein G.
Protein science : a publication of the Protein Society 1994;3(11):1945-52.
1994: A C Wang; P J Lodi; J Qin; Geerten W Vuister; Angela M Gronenborn; G Marius Clore
An efficient triple-resonance experiment for proton-directed sequential backbone assignment of medium-sized proteins.
Journal of magnetic resonance. Series B 1994;105(2):196-8.
1994: G Marius Clore; James G. Omichinski; Kazuyasu Sakaguchi; N Zambrano; H Sakamoto; Ettore Appella; Angela M Gronenborn
High-resolution structure of the oligomerization domain of p53 by multidimensional NMR.
Science (New York, N.Y.) 1994;265(5170):386-91.
1994: B L Grasberger; G Marius Clore; Angela M Gronenborn
High-resolution structure of Ascaris trypsin inhibitor in solution: direct evidence for a pH-induced conformational transition in the reactive site.
Structure (London, England : 1993) 1994;2(7):669-78.
1994: J Qin; G Marius Clore; Angela M Gronenborn
The high-resolution three-dimensional solution structures of the oxidized and reduced states of human thioredoxin.
Structure (London, England : 1993) 1994;2(6):503-22.
1994: Milton H Werner; G Marius Clore; Angela M Gronenborn; Howard A Nash
Symmetry and asymmetry in the function of Escherichia coli integration host factor: implications for target identification by DNA-binding proteins.
Current biology : CB 1994;4(6):477-87.
1994: Milton H Werner; G Marius Clore; Angela M Gronenborn; A Kondoh; Robert J Fisher
Refolding proteins by gel filtration chromatography.
FEBS letters 1994;345(2-3):125-30.
1994: Daniel S Garrett; J Kuszewski; T J Hancock; P J Lodi; Geerten W Vuister; Angela M Gronenborn; G Marius Clore
The impact of direct refinement against three-bond HN-C alpha H coupling constants on protein structure determination by NMR.
Journal of magnetic resonance. Series B 1994;104(1):99-103.
1994: Angela M Gronenborn; G Marius Clore
Identification of N-terminal helix capping boxes by means of 13C chemical shifts.
Journal of biomolecular NMR 1994;4(3):455-8.
1994: P J Lodi; Daniel S Garrett; J Kuszewski; M L Tsang; J A Weatherbee; Warren J Leonard; Angela M Gronenborn; G Marius Clore
High-resolution solution structure of the beta chemokine hMIP-1 beta by multidimensional NMR.
Science (New York, N.Y.) 1994;263(5154):1762-7.
1994: Daniel S Garrett; P J Lodi; Yousif Shamoo; K R Williams; G Marius Clore; Angela M Gronenborn
Determination of the secondary structure and folding topology of an RNA binding domain of mammalian hnRNP A1 protein using three-dimensional heteronuclear magnetic resonance spectroscopy.
Biochemistry 1994;33(10):2852-8.
1994: G Marius Clore; Angela M Gronenborn
Young Investigator Award Lecture. Structures of larger proteins, protein-ligand and protein-DNA complexes by multidimensional heteronuclear NMR.
Protein science : a publication of the Protein Society 1994;3(3):372-90.
1994: G Marius Clore; Adriaan Bax; James G. Omichinski; Angela M Gronenborn
Localization of bound water in the solution structure of a complex of the erythroid transcription factor GATA-1 with DNA.
Structure (London, England : 1993) 1994;2(2):89-94.
1994: R T Clubb; James G. Omichinski; G Marius Clore; Angela M Gronenborn
Mapping the binding surface of interleukin-8 complexed with an N-terminal fragment of the type 1 human interleukin-8 receptor.
FEBS letters 1994;338(1):93-7.
1994: Joseph J Barchi; B Grasberger; Angela M Gronenborn; G Marius Clore
Investigation of the backbone dynamics of the IgG-binding domain of streptococcal protein G by heteronuclear two-dimensional 1H-15N nuclear magnetic resonance spectroscopy.
Protein science : a publication of the Protein Society 1994;3(1):15-21.
1994: G Marius Clore; Angela M Gronenborn
Structures of larger proteins, protein-ligand and protein-DNA complexes by multi-dimensional heteronuclear NMR.
Progress in biophysics and molecular biology 1994;62(2):153-84.
1993: Angela M Gronenborn; G Marius Clore
Identification of the contact surface of a streptococcal protein G domain complexed with a human Fc fragment.
Journal of molecular biology 1993;233(3):331-5.
1993: James G. Omichinski; G Marius Clore; O Schaad; Gary Felsenfeld; C Trainor; Ettore Appella; S J Stahl; Angela M Gronenborn
NMR structure of a specific DNA complex of Zn-containing DNA binding domain of GATA-1.
Science (New York, N.Y.) 1993;261(5120):438-46.
1993: Robert Powers; Daniel S Garrett; CJ March; E A Frieden; Angela M Gronenborn; G Marius Clore
The high-resolution, three-dimensional solution structure of human interleukin-4 determined by multidimensional heteronuclear magnetic resonance spectroscopy.
Biochemistry 1993;32(26):6744-62.
1993: Kazuyasu Sakaguchi; N Zambrano; Eric Baldwin; B A Shapiro; J W Erickson; James G. Omichinski; G Marius Clore; Angela M Gronenborn; Ettore Appella
Identification of a binding site for the human immunodeficiency virus type 1 nucleocapsid protein.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(11):5219-23.
1993: Paul Varley; Angela M Gronenborn; H Christensen; Paul T Wingfield; R H Pain; G Marius Clore
Kinetics of folding of the all-beta sheet protein interleukin-1 beta.
Science (New York, N.Y.) 1993;260(5111):1110-3.
1993: G Marius Clore; M A Robien; Angela M Gronenborn
Exploring the limits of precision and accuracy of protein structures determined by nuclear magnetic resonance spectroscopy.
Journal of molecular biology 1993;231(1):82-102.
1993: B L Grasberger; Angela M Gronenborn; G Marius Clore
Analysis of the backbone dynamics of interleukin-8 by 15N relaxation measurements.
Journal of molecular biology 1993;230(2):364-72.
1993: James G. Omichinski; C Trainor; T Evans; Angela M Gronenborn; G Marius Clore; Gary Felsenfeld
A small single-"finger" peptide from the erythroid transcription factor GATA-1 binds specifically to DNA as a zinc or iron complex.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(5):1676-80.
1992: A Achari; S P Hale; A J Howard; G Marius Clore; Angela M Gronenborn; K D Hardman; M Whitlow
1.67-A X-ray structure of the B2 immunoglobulin-binding domain of streptococcal protein G and comparison to the NMR structure of the B1 domain.
Biochemistry 1992;31(43):10449-57.
1992: Robert Powers; G Marius Clore; Stephen J Stahl; Paul T Wingfield; Angela M Gronenborn
Analysis of the backbone dynamics of the ribonuclease H domain of the human immunodeficiency virus reverse transcriptase using 15N relaxation measurements.
Biochemistry 1992;31(38):9150-7.
1992: Julie D Forman-Kay; G Marius Clore; Stephen J Stahl; Angela M Gronenborn
1H and 15N resonance assignments and secondary structure of the human thioredoxin C62A, C69A, C73A mutant.
Journal of biomolecular NMR 1992;2(5):431-45.
1992: B Shaanan; Angela M Gronenborn; G H Cohen; Gary L Gilliland; B Veerapandian; David Davies; G Marius Clore
Combining experimental information from crystal and solution studies: joint X-ray and NMR refinement.
Science (New York, N.Y.) 1992;257(5072):961-4.
1992: I Chandrasekhar; G Marius Clore; A Szabo; Angela M Gronenborn; Bernard Brooks
A 500 ps molecular dynamics simulation study of interleukin-1 beta in water. Correlation with nuclear magnetic resonance spectroscopy and crystallography.
Journal of molecular biology 1992;226(1):239-50.
1992: Robert Powers; Daniel S Garrett; CJ March; E A Frieden; Angela M Gronenborn; G Marius Clore
Three-dimensional solution structure of human interleukin-4 by multidimensional heteronuclear magnetic resonance spectroscopy.
Science (New York, N.Y.) 1992;256(5064):1673-7.
1992: Daniel S Garrett; Robert Powers; CJ March; E A Frieden; G Marius Clore; Angela M Gronenborn
Determination of the secondary structure and folding topology of human interleukin-4 using three-dimensional heteronuclear magnetic resonance spectroscopy.
Biochemistry 1992;31(17):4347-53.
1992: Robert Powers; Daniel S Garrett; CJ March; E A Frieden; Angela M Gronenborn; G Marius Clore
1H, 15N, 13C, and 13CO assignments of human interleukin-4 using three-dimensional double- and triple-resonance heteronuclear magnetic resonance spectroscopy.
Biochemistry 1992;31(17):4334-46.
1992: M Ikura; G Marius Clore; Angela M Gronenborn; G Zhu; C B Klee; Adriaan Bax
Solution structure of a calmodulin-target peptide complex by multidimensional NMR.
Science (New York, N.Y.) 1992;256(5057):632-8.
1992: James G. Omichinski; G Marius Clore; M Robien; Kazuyasu Sakaguchi; Ettore Appella; Angela M Gronenborn
High-resolution solution structure of the double Cys2His2 zinc finger from the human enhancer binding protein MBP-1.
Biochemistry 1992;31(16):3907-17.
1992: M A Robien; G Marius Clore; James G. Omichinski; R N Perham; Ettore Appella; Kazuyasu Sakaguchi; Angela M Gronenborn
Three-dimensional solution structure of the E3-binding domain of the dihydrolipoamide succinyltransferase core from the 2-oxoglutarate dehydrogenase multienzyme complex of Escherichia coli.
Biochemistry 1992;31(13):3463-71.
1992: Julie D Forman-Kay; G Marius Clore; Angela M Gronenborn
Relationship between electrostatics and redox function in human thioredoxin: characterization of pH titration shifts using two-dimensional homo- and heteronuclear NMR.
Biochemistry 1992;31(13):3442-52.
1992: G Marius Clore; Angela M Gronenborn
Localization of bound water in the solution structure of the immunoglobulin binding domain of streptococcal protein G. Evidence for solvent-induced helical distortion in solution.
Journal of molecular biology 1992;223(4):853-6.
1991: James G. Omichinski; G Marius Clore; Kazuyasu Sakaguchi; Ettore Appella; Angela M Gronenborn
Structural characterization of a 39-residue synthetic peptide containing the two zinc binding domains from the HIV-1 p7 nucleocapsid protein by CD and NMR spectroscopy.
FEBS letters 1991;292(1-2):25-30.
1991: Robert Powers; G Marius Clore; Adriaan Bax; Daniel S Garrett; Stephen J Stahl; Paul T Wingfield; Angela M Gronenborn
Secondary structure of the ribonuclease H domain of the human immunodeficiency virus reverse transcriptase in solution using three-dimensional double and triple resonance heteronuclear magnetic resonance spectroscopy.
Journal of molecular biology 1991;221(4):1081-90.
1991: G Marius Clore; Angela M Gronenborn
Comparison of the solution nuclear magnetic resonance and X-ray crystal structures of human recombinant interleukin-1 beta.
Journal of molecular biology 1991;221(1):47-53.
1991: Angela M Gronenborn; D R Filpula; N Z Essig; A Achari; M Whitlow; Paul T Wingfield; G Marius Clore
A novel, highly stable fold of the immunoglobulin binding domain of streptococcal protein G.
Science (New York, N.Y.) 1991;253(5020):657-61.
1991: Julie D Forman-Kay; Angela M Gronenborn; Paul T Wingfield; G Marius Clore
Determination of the positions of bound water molecules in the solution structure of reduced human thioredoxin by heteronuclear three-dimensional nuclear magnetic resonance spectroscopy.
Journal of molecular biology 1991;220(2):209-16.
1991: G Marius Clore; Angela M Gronenborn
Structures of larger proteins in solution: three- and four-dimensional heteronuclear NMR spectroscopy.
Science (New York, N.Y.) 1991;252(5011):1390-9.
1991: G Marius Clore; Adriaan Bax; Angela M Gronenborn
Stereospecific assignment of beta-methylene protons in larger proteins using 3D 15N-separated Hartmann-Hahn and 13C-separated rotating frame Overhauser spectroscopy.
Journal of biomolecular NMR 1991;1(1):13-22.
1991: Kazuyasu Sakaguchi; Ettore Appella; James G. Omichinski; G Marius Clore; Angela M Gronenborn
Specific DNA binding to a major histocompatibility complex enhancer sequence by a synthetic 57-residue double zinc finger peptide from a human enhancer binding protein.
The Journal of biological chemistry 1991;266(11):7306-11.
1991: Julie D Forman-Kay; G Marius Clore; Paul T Wingfield; Angela M Gronenborn
High-resolution three-dimensional structure of reduced recombinant human thioredoxin in solution.
Biochemistry 1991;30(10):2685-98.
1991: G Marius Clore; Paul T Wingfield; Angela M Gronenborn
High-resolution three-dimensional structure of interleukin 1 beta in solution by three- and four-dimensional nuclear magnetic resonance spectroscopy.
Biochemistry 1991;30(9):2315-23.
1991: G Marius Clore; Angela M Gronenborn
Comparison of the solution nuclear magnetic resonance and crystal structures of interleukin-8. Possible implications for the mechanism of receptor binding.
Journal of molecular biology 1991;217(4):611-20.
1991: Angela M Gronenborn; G Marius Clore
Modeling the three-dimensional structure of the monocyte chemo-attractant and activating protein MCAF/MCP-1 on the basis of the solution structure of interleukin-8.
Protein engineering 1991;4(3):263-9.
1991: G Marius Clore; Lewis E Kay; Adriaan Bax; Angela M Gronenborn
Four-dimensional 13C/13C-edited nuclear Overhauser enhancement spectroscopy of a protein in solution: application to interleukin 1 beta.
Biochemistry 1991;30(1):12-8.
1990: James G. Omichinski; G Marius Clore; Ettore Appella; Kazuyasu Sakaguchi; Angela M Gronenborn
High-resolution three-dimensional structure of a single zinc finger from a human enhancer binding protein in solution.
Biochemistry 1990;29(40):9324-34.
1990: S Patricia Becerra; G Marius Clore; Angela M Gronenborn; A R Karlström; Stephen J Stahl; Samuel H Wilson; P T Wingfield
Purification and characterization of the RNase H domain of HIV-1 reverse transcriptase expressed in recombinant Escherichia coli.
FEBS letters 1990;270(1-2):76-80.
1990: G Marius Clore; Adriaan Bax; P C Driscoll; Paul T Wingfield; Angela M Gronenborn
Assignment of the side-chain 1H and 13C resonances of interleukin-1 beta using double- and triple-resonance heteronuclear three-dimensional NMR spectroscopy.
Biochemistry 1990;29(35):8172-84.
1990: G Marius Clore; P C Driscoll; Paul T Wingfield; Angela M Gronenborn
Low resolution structure of interleukin-1 beta in solution derived from 1H-15N heteronuclear three-dimensional nuclear magnetic resonance spectroscopy.
Journal of molecular biology 1990;214(4):811-7.
1990: G Marius Clore; P C Driscoll; Paul T Wingfield; Angela M Gronenborn
Analysis of the backbone dynamics of interleukin-1 beta using two-dimensional inverse detected heteronuclear 15N-1H NMR spectroscopy.
Biochemistry 1990;29(32):7387-401.
1990: Lewis E Kay; G Marius Clore; Adriaan Bax; Angela M Gronenborn
Four-dimensional heteronuclear triple-resonance NMR spectroscopy of interleukin-1 beta in solution.
Science (New York, N.Y.) 1990;249(4967):411-4.
1990: G Marius Clore; Adriaan Bax; Paul T Wingfield; Angela M Gronenborn
Identification and localization of bound internal water in the solution structure of interleukin 1 beta by heteronuclear three-dimensional 1H rotating-frame Overhauser 15N-1H multiple quantum coherence NMR spectroscopy.
Biochemistry 1990;29(24):5671-6.
1990: P C Driscoll; Angela M Gronenborn; Paul T Wingfield; G Marius Clore
Determination of the secondary structure and molecular topology of interleukin-1 beta by use of two- and three-dimensional heteronuclear 15N-1H NMR spectroscopy.
Biochemistry 1990;29(19):4668-82.
1990: P C Driscoll; G Marius Clore; D Marion; Paul T Wingfield; Angela M Gronenborn
Complete resonance assignment for the polypeptide backbone of interleukin 1 beta using three-dimensional heteronuclear NMR spectroscopy.
Biochemistry 1990;29(14):3542-56.
1990: Michael Nilges; G Marius Clore; Angela M Gronenborn
1H-NMR stereospecific assignments by conformational data-base searches.
Biopolymers 1990;29(4-5):813-22.
1990: G Marius Clore; Ettore Appella; M Yamada; K Matsushima; Angela M Gronenborn
Three-dimensional structure of interleukin 8 in solution.
Biochemistry 1990;29(7):1689-96.
1990: J E Forman-Kay; Angela M Gronenborn; Lewis E Kay; Paul T Wingfield; G Marius Clore
Studies on the solution conformation of human thioredoxin using heteronuclear 15N-1H nuclear magnetic resonance spectroscopy.
Biochemistry 1990;29(6):1566-72.
1990: Angela M Gronenborn; Michael Nilges; R J Peanasky; G Marius Clore
Sequential resonance assignment and secondary structure determination of the Ascaris trypsin inhibitor, a member of a novel class of proteinase inhibitors.
Biochemistry 1990;29(1):183-9.
1990: Ettore Appella; K Matsushima; J J Oppenheim; T Yoshimura; E J Leonard; G Marius Clore; Angela M Gronenborn
Determination of the primary and secondary structure of NAP-1/IL-8 and a monocyte chemoattractant protein, MCP-1/MCAF.
Progress in clinical and biological research 1990;349():405-17.
1989: G Marius Clore; Ettore Appella; M Yamada; K Matsushima; Angela M Gronenborn
Determination of the secondary structure of interleukin-8 by nuclear magnetic resonance spectroscopy.
The Journal of biological chemistry 1989;264(32):18907-11.
1989: J Kraulis; G Marius Clore; Michael Nilges; T A Jones; G Pettersson; J Knowles; Angela M Gronenborn
Determination of the three-dimensional solution structure of the C-terminal domain of cellobiohydrolase I from Trichoderma reesei. A study using nuclear magnetic resonance and hybrid distance geometry-dynamical simulated annealing.
Biochemistry 1989;28(18):7241-57.
1989: Julie D Forman-Kay; G Marius Clore; P C Driscoll; Paul T Wingfield; F M Richards; Angela M Gronenborn
A proton nuclear magnetic resonance assignment and secondary structure determination of recombinant human thioredoxin.
Biochemistry 1989;28(17):7088-97.
1989: D Marion; P C Driscoll; Lewis E Kay; Paul T Wingfield; Adriaan Bax; Angela M Gronenborn; G Marius Clore
Overcoming the overlap problem in the assignment of 1H NMR spectra of larger proteins by use of three-dimensional heteronuclear 1H-15N Hartmann-Hahn-multiple quantum coherence and nuclear Overhauser-multiple quantum coherence spectroscopy: application to interleukin 1 beta.
Biochemistry 1989;28(15):6150-6.
1989: Angela M Gronenborn; G Marius Clore
Analysis of the relative contributions of the nuclear Overhauser interproton distance restraints and the empirical energy function in the calculation of oligonucleotide structures using restrained molecular dynamics.
Biochemistry 1989;28(14):5978-84.
1989: Angela M Gronenborn; Paul T Wingfield; G Marius Clore
Determination of the secondary structure of the DNA binding protein Ner from phage Mu using 1H homonuclear and 15N-1H heteronuclear NMR spectroscopy.
Biochemistry 1989;28(12):5081-9.
1989: P J Folkers; G Marius Clore; P C Driscoll; J Dodt; S Köhler; Angela M Gronenborn
Solution structure of recombinant hirudin and the Lys-47----Glu mutant: a nuclear magnetic resonance and hybrid distance geometry-dynamical simulated annealing study.
Biochemistry 1989;28(6):2601-17.
1989: P C Driscoll; Angela M Gronenborn; L Beress; G Marius Clore
Determination of the three-dimensional solution structure of the antihypertensive and antiviral protein BDS-I from the sea anemone Anemonia sulcata: a study using nuclear magnetic resonance and hybrid distance geometry-dynamical simulated annealing.
Biochemistry 1989;28(5):2188-98.
1989: P C Driscoll; G Marius Clore; L Beress; Angela M Gronenborn
A proton nuclear magnetic resonance study of the antihypertensive and antiviral protein BDS-I from the sea anemone Anemonia sulcata: sequential and stereospecific resonance assignment and secondary structure.
Biochemistry 1989;28(5):2178-87.
1989: P C Driscoll; Angela M Gronenborn; G Marius Clore
The influence of stereospecific assignments on the determination of three-dimensional structures of proteins by nuclear magnetic resonance spectroscopy. Application to the sea anemone protein BDS-I.
FEBS letters 1989;243(2):223-33.
1989: Angela M Gronenborn; Adriaan Bax; Paul T Wingfield; G Marius Clore
A powerful method of sequential proton resonance assignment in proteins using relayed 15N-1H multiple quantum coherence spectroscopy.
FEBS letters 1989;243(1):93-8.
1988: G Marius Clore; Adriaan Bax; Paul T Wingfield; Angela M Gronenborn
Long-range 15N-1H correlation as an aid to sequential proton resonance assignment of proteins. Application to the DNA-binding protein ner from phage Mu.
FEBS letters 1988;238(1):17-21.