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Philippe Gros

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Co-Publications
Name
38
Malo, Danielle
24
Skamene, Emil
21
Schurr, Erwin
14
Canonne-Hergaux, François
13
Stevenson, Mary
13
Gauthier, Susan
12
Min-Oo, Gundula
12
Grinstein, Sergio
12
Ruetz, S
11
Levenson, Robert
11
Fortin, Anny
10
Lam-Yuk-Tseung, Steven
10
Govoni, Gregory
10
Gruenheid, Samantha
10
Pelletier, Jerry

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Publications

TOP 3
Fortier Anne; Doiron Karine; Saleh Maya; Grinstein Sergio; Gros Philippe
Restriction of Legionella pneumophila replication in macrophages requires concerted action of the transcriptional regulators Irf1 and Irf8 and nod-like receptors Naip5 and Nlrc4.
Ayi Kodjo; Liles W Conrad; Gros Philippe; Kain Kevin C
Adenosine triphosphate depletion of erythrocytes simulates the phenotype associated with pyruvate kinase deficiency and confers protection against Plasmodium falciparum in vitro.
Bongfen Silayuv E; Laroque Aurélie; Berghout Joanne; Gros Philippe
Genetic and genomic analyses of host-pathogen interactions in malaria.

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All Publications

2009: Fortier Anne; Doiron Karine; Saleh Maya; Grinstein Sergio; Gros Philippe
Restriction of Legionella pneumophila replication in macrophages requires concerted action of the transcriptional regulators Irf1 and Irf8 and nod-like receptors Naip5 and Nlrc4.
Infection and immunity 2009;77(11):4794-805.
2009: Ayi Kodjo; Liles W Conrad; Gros Philippe; Kain Kevin C
Adenosine triphosphate depletion of erythrocytes simulates the phenotype associated with pyruvate kinase deficiency and confers protection against Plasmodium falciparum in vitro.
The Journal of infectious diseases 2009;200(8):1289-99.
2009: Bongfen Silayuv E; Laroque Aurélie; Berghout Joanne; Gros Philippe
Genetic and genomic analyses of host-pathogen interactions in malaria.
Trends in parasitology 2009;25(9):417-22.
2009: Czachorowski Maciej; Lam-Yuk-Tseung Steven; Cellier Mathieu; Gros Philippe
Transmembrane topology of the mammalian Slc11a2 iron transporter.
Biochemistry 2009;48(35):8422-34.
2009: Kibar Zoha; Bosoi Ciprian M; Kooistra Megan; Salem Sandra; Finnell Richard H; De Marco Patrizia; Merello Elisa; Bassuk Alexander G; Capra Valeria; Gros Philippe
Novel mutations in VANGL1 in neural tube defects.
Human mutation 2009;30(7):E706-15.
2009: Marquis Jean-François; Lacourse Ronald; Ryan Lynn; North Robert J; Gros Philippe
Genetic and functional characterization of the mouse Trl3 locus in defense against tuberculosis.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(6):3757-67.
2009: Marquis Jean-François; LaCourse Ronald; Ryan Lynn; North Robert J; Gros Philippe
Disseminated and rapidly fatal tuberculosis in mice bearing a defective allele at IFN regulatory factor 8.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(5):3008-15.
2008: Divangahi Maziar; Mostowy Serge; Coulombe François; Kozak Robert; Guillot Loïc; Veyrier Frédéric; Kobayashi Koichi S; Flavell Richard A; Gros Philippe; Behr Marcel A
NOD2-deficient mice have impaired resistance to Mycobacterium tuberculosis infection through defective innate and adaptive immunity.
Journal of immunology (Baltimore, Md. : 1950) 2008;181(10):7157-65.
2008: Carrier Isabelle; Gros Philippe
Investigating the role of the invariant carboxylate residues E552 and E1197 in the catalytic activity of Abcb1a (mouse Mdr3).
The FEBS journal 2008;275(13):3312-24.
2008: Min-Oo G; Lindqvist L; Vaglenov A; Wang C; Fortin P; Li Y; Kaltenboeck B; Gros P
Genetic control of susceptibility to pulmonary infection with Chlamydia pneumoniae in the mouse.
Genes and immunity 2008;9(4):383-8.
2008: Patel Samir N; Berghout Joanne; Lovegrove Fiona E; Ayi Kodjo; Conroy Andrea; Serghides Lena; Min-oo Gundula; Gowda D Channe; Sarma J Vidya; Rittirsch Daniel; Ward Peter A; Liles W Conrad; Gros Philippe; Kain Kevin C
C5 deficiency and C5a or C5aR blockade protects against cerebral malaria.
The Journal of experimental medicine 2008;205(5):1133-43.
2008: Ayi Kodjo; Min-Oo Gundula; Serghides Lena; Crockett Maryanne; Kirby-Allen Melanie; Quirt Ian; Gros Philippe; Kain Kevin C
Pyruvate kinase deficiency and malaria.
The New England journal of medicine 2008;358(17):1805-10.
2008: Cai Jie; Damaraju Vijaya L; Groulx Normand; Mowles Delores; Peng Yunshan; Robins Morris J; Cass Carol E; Gros Philippe
Two distinct molecular mechanisms underlying cytarabine resistance in human leukemic cells.
Cancer research 2008;68(7):2349-57.
2008: Torban Elena; Patenaude Anne-Marie; Leclerc Severine; Rakowiecki Staci; Gauthier Susan; Andelfinger Gregor; Epstein Douglas J; Gros Philippe
Genetic interaction between members of the Vangl family causes neural tube defects in mice.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(9):3449-54.
2008: Marquis Jean-François; Nantel André; LaCourse Ronald; Ryan Lynn; North Robert J; Gros Philippe
Fibrotic response as a distinguishing feature of resistance and susceptibility to pulmonary infection with Mycobacterium tuberculosis in mice.
Infection and immunity 2008;76(1):78-88.
2008: Marquis J-F; Gros P
Genetic analysis of resistance to infections in mice: A/J meets C57BL/6J.
Current topics in microbiology and immunology 2008;321():27-57.
2008: Vidal S M; Malo D; Marquis J-F; Gros P
Forward genetic dissection of immunity to infection in the mouse.
Annual review of immunology 2008;26():81-132.
2007: Gallant C J; Malik S; Jabado N; Cellier M; Simkin L; Finlay B B; Graviss E A; Gros P; Musser J M; Schurr E
Reduced in vitro functional activity of human NRAMP1 (SLC11A1) allele that predisposes to increased risk of pediatric tuberculosis disease.
Genes and immunity 2007;8(8):691-8.
2007: Roy Marie-France; Riendeau Noémie; Bédard Christian; Hélie Pierre; Min-Oo Gundula; Turcotte Karine; Gros Philippe; Canonne-Hergaux François; Malo Danielle
Pyruvate kinase deficiency confers susceptibility to Salmonella typhimurium infection in mice.
The Journal of experimental medicine 2007;204(12):2949-61.
2007: Turcotte Karine; Gauthier Susan; Malo Danielle; Tam Mifong; Stevenson Mary M; Gros Philippe
Icsbp1/IRF-8 is required for innate and adaptive immune responses against intracellular pathogens.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(4):2467-76.
2007: Min-Oo Gundula; Tam Mifong; Stevenson Mary M; Gros Philippe
Pyruvate kinase deficiency: correlation between enzyme activity, extent of hemolytic anemia and protection against malaria in independent mouse mutants.
Blood cells, molecules & diseases 2007;39(1):63-9.
2007: Kibar Z; Capra V; Gros P
Toward understanding the genetic basis of neural tube defects.
Clinical genetics 2007;71(4):295-310.
2007: Kibar Zoha; Torban Elena; McDearmid Jonathan R; Reynolds Annie; Berghout Joanne; Mathieu Melissa; Kirillova Irena; De Marco Patrizia; Merello Elisa; Hayes Julie M; Wallingford John B; Drapeau Pierre; Capra Valeria; Gros Philippe
Mutations in VANGL1 associated with neural-tube defects.
The New England journal of medicine 2007;356(14):1432-7.
2007: Fortier Anne; de Chastellier Chantal; Balor Stéphanie; Gros Philippe
Birc1e/Naip5 rapidly antagonizes modulation of phagosome maturation by Legionella pneumophila.
Cellular microbiology 2007;9(4):910-23.
2007: Apuzzo Sergio; Gros Philippe
Cooperative interactions between the two DNA binding domains of Pax3: helix 2 of the paired domain is in the proximity of the amino terminus of the homeodomain.
Biochemistry 2007;46(11):2984-93.
2007: Min-Oo Gundula; Fortin Anny; Pitari Giuseppina; Tam Mifong; Stevenson Mary M; Gros Philippe
Complex genetic control of susceptibility to malaria: positional cloning of the Char9 locus.
The Journal of experimental medicine 2007;204(3):511-24.
2007: Marquis Jean-François; Gros Philippe
Intracellular Leishmania: your iron or mine?
Trends in microbiology 2007;15(3):93-5.
2007: Carrier Isabelle; Urbatsch Ina L; Senior Alan E; Gros Philippe
Mutational analysis of conserved aromatic residues in the A-loop of the ABC transporter ABCB1A (mouse Mdr3).
FEBS letters 2007;581(2):301-8.
2007: Torban Elena; Wang Hui-Jun; Patenaude Anne-Marie; Riccomagno Martin; Daniels Eugene; Epstein Douglas; Gros P
Tissue, cellular and sub-cellular localization of the Vangl2 protein during embryonic development: effect of the Lp mutation.
Gene expression patterns : GEP 2007;7(3):346-54.
2007: Min-Oo Gundula; Stevenson Mary M; Fortin Anny; Gros Philippe
Genetic control of host-pathogen interactions in mice.
Novartis Foundation symposium 2007;281():156-65; discussion 165-8, 208-9.
2007: Fortin Anny; Diez Eduardo; Henderson Janet E; Mogil Jeffrey S; Gros Philippe; Skamene Emil
The AcB/BcA recombinant congenic strains of mice: strategies for phenotype dissection, mapping and cloning of quantitative trait genes.
Novartis Foundation symposium 2007;281():141-53; discussion 153-5, 208-9.
2006: Turcotte K; Loredo-Osti J C; Fortin P; Schurr E; Morgan K; Gros P
Complex genetic control of susceptibility to Mycobacterium bovis (Bacille Calmette-Guérin) infection in wild-derived Mus spretus mice.
Genes and immunity 2006;7(8):684-7.
2006: Belley Adam; Callejo Mario; Arhin Francis; Dehbi Mohammed; Fadhil Ibtihal; Liu Jing; McKay Geoffrey; Srikumar Ramakrishnan; Bauda Pascale; Bergeron Dominique; Ha Nhuan; Dubow Michael; Gros Philippe; Pelletier Jerry; Moeck Greg
Competition of bacteriophage polypeptides with native replicase proteins for binding to the DNA sliding clamp reveals a novel mechanism for DNA replication arrest in Staphylococcus aureus.
Molecular microbiology 2006;62(4):1132-43.
2006: Lam-Yuk-Tseung Steven; Picard Virginie; Gros Philippe
Identification of a tyrosine-based motif (YGSI) in the amino terminus of Nramp1 (Slc11a1) that is important for lysosomal targeting.
The Journal of biological chemistry 2006;281(42):31677-88.
2006: Arhin Francis; Bélanger Odette; Ciblat Stéphane; Dehbi Mohammed; Delorme Daniel; Dietrich Evelyne; Dixit Dilip; Lafontaine Yanick; Lehoux Dario; Liu Jing; McKay Geoffrey A; Moeck Greg; Reddy Ranga; Rose Yannick; Srikumar Ramakrishnan; Tanaka Kelly S E; Williams Daniel M; Gros Philippe; Pelletier Jerry; Parr Thomas R; Far Adel Rafai
A new class of small molecule RNA polymerase inhibitors with activity against rifampicin-resistant Staphylococcus aureus.
Bioorganic & medicinal chemistry 2006;14(17):5812-32.
2006: Mullick Alaka; Leon Zully; Min-Oo Gundula; Berghout Joanne; Lo Rita; Daniels Eugene; Gros Philippe
Cardiac failure in C5-deficient A/J mice after Candida albicans infection.
Infection and immunity 2006;74(8):4439-51.
2006: Apuzzo Sergio; Gros Philippe
The paired domain of Pax3 contains a putative homeodomain interaction pocket defined by cysteine scanning mutagenesis.
Biochemistry 2006;45(23):7154-61.
2006: Tuite Ashleigh; Gros Philippe
The impact of genomics on the analysis of host resistance to infectious disease.
Microbes and infection / Institut Pasteur 2006;8(6):1647-53.
2006: Caron Judith; Larivière Line; Nacache Mayss; Tam Mifong; Stevenson Mary M; McKerly Colin; Gros Philippe; Malo Danielle
Influence of Slc11a1 on the outcome of Salmonella enterica serovar Enteritidis infection in mice is associated with Th polarization.
Infection and immunity 2006;74(5):2787-802.
2006: Lam-Yuk-Tseung Steven; Camaschella Clara; Iolascon Achille; Gros Philippe
A novel R416C mutation in human DMT1 (SLC11A2) displays pleiotropic effects on function and causes microcytic anemia and hepatic iron overload.
Blood cells, molecules & diseases 2006;36(3):347-54.
2006: McKay Geoffrey A; Reddy Ranga; Arhin Francis; Belley Adam; Lehoux Dario; Moeck Greg; Sarmiento Ingrid; Parr Thomas R; Gros Philippe; Pelletier Jerry; Far Adel Rafai
Triaminotriazine DNA helicase inhibitors with antibacterial activity.
Bioorganic & medicinal chemistry letters 2006;16(5):1286-90.
2006: Lam-Yuk-Tseung Steven; Gros Philippe
Distinct targeting and recycling properties of two isoforms of the iron transporter DMT1 (NRAMP2, Slc11A2).
Biochemistry 2006;45(7):2294-301.
2006: Kwan Tony; Liu Jing; Dubow Michael; Gros Philippe; Pelletier Jerry
Comparative genomic analysis of 18 Pseudomonas aeruginosa bacteriophages.
Journal of bacteriology 2006;188(3):1184-7.
2006: Martin-Orozco Natalia; Touret Nicolas; Zaharik Michael L; Park Edwin; Kopelman Raoul; Miller Samuel; Finlay B Brett; Gros Philippe; Grinstein Sergio
Visualization of vacuolar acidification-induced transcription of genes of pathogens inside macrophages.
Molecular biology of the cell 2006;17(1):498-510.
2005: Tuite A; Elias M; Picard S; Mullick A; Gros P
Genetic control of susceptibility to Candida albicans in susceptible A/J and resistant C57BL/6J mice.
Genes and immunity 2005;6(8):672-82.
2005: Lam-Yuk-Tseung Steven; Touret Nicolas; Grinstein Sergio; Gros Philippe
Carboxyl-terminus determinants of the iron transporter DMT1/SLC11A2 isoform II (-IRE/1B) mediate internalization from the plasma membrane into recycling endosomes.
Biochemistry 2005;44(36):12149-59.
2005: Lam-Yuk-Tseung Steven; Mathieu Melissa; Gros Philippe
Functional characterization of the E399D DMT1/NRAMP2/SLC11A2 protein produced by an exon 12 mutation in a patient with microcytic anemia and iron overload.
Blood cells, molecules & diseases 2005;35(2):212-6.
2005: Fortier Anne; Diez Eduardo; Gros Philippe
Naip5/Birc1e and susceptibility to Legionella pneumophila.
Trends in microbiology 2005;13(7):328-35.
2005: Min-Oo Gundula; Gros Philippe
Erythrocyte variants and the nature of their malaria protective effect.
Cellular microbiology 2005;7(6):753-63.
2005: Fortier Anne; Min-Oo Gundula; Forbes John; Lam-Yuk-Tseung Steven; Gros Philippe
Single gene effects in mouse models of host: pathogen interactions.
Journal of leukocyte biology 2005;77(6):868-77.
2005: Ing Rebecca; Gros Philippe; Stevenson Mary M
Interleukin-15 enhances innate and adaptive immune responses to blood-stage malaria infection in mice.
Infection and immunity 2005;73(5):3172-7.
2005: Kwan Tony; Liu Jing; DuBow Michael; Gros Philippe; Pelletier Jerry
The complete genomes and proteomes of 27 Staphylococcus aureus bacteriophages.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(14):5174-9.
2005: Turcotte Karine; Gauthier Susan; Tuite Ashleigh; Mullick Alaka; Malo Danielle; Gros Philippe
A mutation in the Icsbp1 gene causes susceptibility to infection and a chronic myeloid leukemia-like syndrome in BXH-2 mice.
The Journal of experimental medicine 2005;201(6):881-90.
2005: Karwatsky Joel; Leimanis Mara; Cai Jie; Gros Philippe; Georges Elias
The leucotriene C4 binding sites in multidrug resistance protein 1 (ABCC1) include the first membrane multiple spanning domain.
Biochemistry 2005;44(1):340-51.
2004: Torban Elena; Wang Hui-Jun; Groulx Normand; Gros Philippe
Independent mutations in mouse Vangl2 that cause neural tube defects in looptail mice impair interaction with members of the Dishevelled family.
The Journal of biological chemistry 2004;279(50):52703-13.
2004: Torban Elena; Kor Christine; Gros Philippe
Van Gogh-like2 (Strabismus) and its role in planar cell polarity and convergent extension in vertebrates.
Trends in genetics : TIG 2004;20(11):570-7.
2004: Tuite A; Mullick A; Gros P
Genetic analysis of innate immunity in resistance to Candida albicans.
Genes and immunity 2004;5(7):576-87.
2004: Mullick Alaka; Elias Miria; Picard Serge; Bourget Lucie; Jovcevski Orce; Gauthier Susan; Tuite Ashleigh; Harakidas Penelope; Bihun Craig; Massie Bernard; Gros Philippe
Dysregulated inflammatory response to Candida albicans in a C5-deficient mouse strain.
Infection and immunity 2004;72(10):5868-76.
2004: Touret Nicolas; Martin-Orozco Natalia; Paroutis Paul; Furuya Wendy; Lam-Yuk-Tseung Steven; Forbes John; Gros Philippe; Grinstein Sergio
Molecular and cellular mechanisms underlying iron transport deficiency in microcytic anemia.
Blood 2004;104(5):1526-33.
2004: Apuzzo Sergio; Abdelhakim Aliaa; Fortin Anouk S; Gros Philippe
Cross-talk between the paired domain and the homeodomain of Pax3: DNA binding by each domain causes a structural change in the other domain, supporting interdependence for DNA Binding.
The Journal of biological chemistry 2004;279(32):33601-12.
2004: Min-Oo G; Fortin A; Tam M-F; Gros P; Stevenson M M
Phenotypic expression of pyruvate kinase deficiency and protection against malaria in a mouse model.
Genes and immunity 2004;5(3):168-75.
2004: Turcotte Karine; Gauthier Susan; Mitsos Loukia-Maria; Shustik Chaim; Copeland Neal G; Jenkins Nancy A; Fournet Jean-Christophe; Jolicoeur Paul; Gros Philippe
Genetic control of myeloproliferation in BXH-2 mice.
Blood 2004;103(6):2343-50.
2004: Liu Jing; Dehbi Mohammed; Moeck Greg; Arhin Francis; Bauda Pascale; Bergeron Dominique; Callejo Mario; Ferretti Vincent; Ha Nhuan; Kwan Tony; McCarty John; Srikumar Ramakrishnan; Williams Dan; Wu Jinzi J; Gros Philippe; Pelletier Jerry; DuBow Michael
Antimicrobial drug discovery through bacteriophage genomics.
Nature biotechnology 2004;22(2):185-91.
2003: Min-Oo Gundula; Fortin Anny; Tam Mi-Fong; Nantel André; Stevenson Mary M; Gros Philippe
Pyruvate kinase deficiency in mice protects against malaria.
Nature genetics 2003;35(4):357-62.
2003: Carrier Isabelle; Julien Michel; Gros Philippe
Analysis of catalytic carboxylate mutants E552Q and E1197Q suggests asymmetric ATP hydrolysis by the two nucleotide-binding domains of P-glycoprotein.
Biochemistry 2003;42(44):12875-85.
2003: Kibar Zoha; Gauthier Susan; Lee Seung-Hwan; Vidal Silvia; Gros Philippe
Rescue of the neural tube defect of loop-tail mice by a BAC clone containing the Ltap gene.
Genomics 2003;82(3):397-400.
2003: Forbes John R; Gros Philippe
Iron, manganese, and cobalt transport by Nramp1 (Slc11a1) and Nramp2 (Slc11a2) expressed at the plasma membrane.
Blood 2003;102(5):1884-92.
2003: Touret Nicolas; Furuya Wendy; Forbes John; Gros Philippe; Grinstein Sergio
Dynamic traffic through the recycling compartment couples the metal transporter Nramp2 (DMT1) with the transferrin receptor.
The Journal of biological chemistry 2003;278(28):25548-57.
2003: Mitsos Loukia-Maria; Cardon Lon R; Ryan Lynn; LaCourse Ronald; North Robert J; Gros Philippe
Susceptibility to tuberculosis: a locus on mouse chromosome 19 (Trl-4) regulates Mycobacterium tuberculosis replication in the lungs.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(11):6610-5.
2003: Lam-Yuk-Tseung Steven; Gros Philippe
Genetic control of susceptibility to bacterial infections in mouse models.
Cellular microbiology 2003;5(5):299-313.
2003: Jabado Nada; Cuellar-Mata Patricia; Grinstein Sergio; Gros Philippe
Iron chelators modulate the fusogenic properties of Salmonella-containing phagosomes.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(10):6127-32.
2003: Lam-Yuk-Tseung Steven; Govoni Gregory; Forbes John; Gros Philippe
Iron transport by Nramp2/DMT1: pH regulation of transport by 2 histidines in transmembrane domain 6.
Blood 2003;101(9):3699-707.
2003: Karwatsky Joel; Daoud Roni; Cai Jie; Gros Philippe; Georges Elias
Binding of a photoaffinity analogue of glutathione to MRP1 (ABCC1) within two cytoplasmic regions (L0 and L1) as well as transmembrane domains 10-11 and 16-17.
Biochemistry 2003;42(11):3286-94.
2003: Lee Seung-Hwan; Zafer Ahmed; de Repentigny Yves; Kothary Rashmi; Tremblay Michel L; Gros Philippe; Duplay Pascale; Webb John R; Vidal Silvia M
Transgenic expression of the activating natural killer receptor Ly49H confers resistance to cytomegalovirus in genetically susceptible mice.
The Journal of experimental medicine 2003;197(4):515-26.
2003: Cai Jie; Gros Philippe
Overexpression, purification, and functional characterization of ATP-binding cassette transporters in the yeast, Pichia pastoris.
Biochimica et biophysica acta 2003;1610(1):63-76.
2003: Diez Eduardo; Lee Seung-Hwan; Gauthier Susan; Yaraghi Zahra; Tremblay Michel; Vidal Silvia; Gros Philippe
Birc1e is the gene within the Lgn1 locus associated with resistance to Legionella pneumophila.
Nature genetics 2003;33(1):55-60.
2002: Su Zhong; Fortin Anny; Gros Philippe; Stevenson Mary M
Opsonin-independent phagocytosis: an effector mechanism against acute blood-stage Plasmodium chabaudi AS infection.
The Journal of infectious diseases 2002;186(9):1321-9.
2002: Boyer E; Bergevin I; Malo D; Gros P; Cellier M F M
Acquisition of Mn(II) in addition to Fe(II) is required for full virulence of Salmonella enterica serovar Typhimurium.
Infection and immunity 2002;70(11):6032-42.
2002: Apuzzo Sergio; Gros Philippe
Site-specific modification of single cysteine Pax3 mutants reveals reciprocal regulation of DNA binding activity of the paired and homeo domain.
Biochemistry 2002;41(40):12076-85.
2002: Fortin A; Stevenson M M; Gros P
Susceptibility to malaria as a complex trait: big pressure from a tiny creature.
Human molecular genetics 2002;11(20):2469-78.
2002: Jabado Nada; Canonne-Hergaux François; Gruenheid Samantha; Picard Virgine; Gros Philippe
Iron transporter Nramp2/DMT-1 is associated with the membrane of phagosomes in macrophages and Sertoli cells.
Blood 2002;100(7):2617-22.
2002: Frehel Claude; Canonne-Hergaux François; Gros Philippe; De Chastellier Chantal
Effect of Nramp1 on bacterial replication and on maturation of Mycobacterium avium-containing phagosomes in bone marrow-derived mouse macrophages.
Cellular microbiology 2002;4(8):541-56.
2002: Canonne-Hergaux François; Gros Philippe
Expression of the iron transporter DMT1 in kidney from normal and anemic mk mice.
Kidney international 2002;62(1):147-56.
2002: Canonne-Hergaux François; Calafat Jero; Richer Etienne; Cellier Mathieu; Grinstein Sergio; Borregaard Neils; Gros Philippe
Expression and subcellular localization of NRAMP1 in human neutrophil granules.
Blood 2002;100(1):268-75.
2002: Cai Jie; Daoud Roni; Alqawi Omar; Georges Elias; Pelletier Jerry; Gros Philippe
Nucleotide binding and nucleotide hydrolysis properties of the ABC transporter MRP6 (ABCC6).
Biochemistry 2002;41(25):8058-67.
2002: Fortin A; Stevenson M M; Gros P
Complex genetic control of susceptibility to malaria in mice.
Genes and immunity 2002;3(4):177-86.
2002: Roig E A; Richer E; Canonne-Hergaux F; Gros P; Cellier M F M
Regulation of NRAMP1 gene expression by 1alpha,25-dihydroxy-vitamin D(3) in HL-60 phagocytes.
Journal of leukocyte biology 2002;71(5):890-904.
2002: Sebastiani Giovanna; Blais Véronique; Sancho Vanessa; Vogel Stefanie N; Stevenson Mary M; Gros Philippe; Lapointe Jean-Martin; Rivest Serge; Malo Danielle
Host immune response to Salmonella enterica serovar Typhimurium infection in mice derived from wild strains.
Infection and immunity 2002;70(4):1997-2009.
2002: Vigano Catherine; Julien Michel; Carrier Isabelle; Gros Philippe; Ruysschaert Jean-Marie
Structural and functional asymmetry of the nucleotide-binding domains of P-glycoprotein investigated by attenuated total reflection Fourier transform infrared spectroscopy.
The Journal of biological chemistry 2002;277(7):5008-16.
2002: Cuellar-Mata Patricia; Jabado Nada; Liu Jun; Furuya Wendy; Finlay B Brett; Gros Philippe; Grinstein Sergio
Nramp1 modifies the fusion of Salmonella typhimurium-containing vacuoles with cellular endomembranes in macrophages.
The Journal of biological chemistry 2002;277(3):2258-65.
2001: Canonne-Hergaux F; Zhang A S; Ponka P; Gros P
Characterization of the iron transporter DMT1 (NRAMP2/DCT1) in red blood cells of normal and anemic mk/mk mice.
Blood 2001;98(13):3823-30.
2001: Fortin A; Cardon L R; Tam M; Skamene E; Stevenson M M; Gros P
Identification of a new malaria susceptibility locus (Char4) in recombinant congenic strains of mice.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(19):10793-8.
2001: Forbes J R; Gros P
Divalent-metal transport by NRAMP proteins at the interface of host-pathogen interactions.
Trends in microbiology 2001;9(8):397-403.
2001: Cai J; Daoud R; Georges E; Gros P
Functional expression of multidrug resistance protein 1 in Pichia pastoris.
Biochemistry 2001;40(28):8307-16.
2001: Kibar Z; Vogan K J; Groulx N; Justice M J; Underhill D A; Gros P
Ltap, a mammalian homolog of Drosophila Strabismus/Van Gogh, is altered in the mouse neural tube mutant Loop-tail.
Nature genetics 2001;28(3):251-5.
2001: Fortin A; Diez E; Rochefort D; Laroche L; Malo D; Rouleau G A; Gros P; Skamene E
Recombinant congenic strains derived from A/J and C57BL/6J: a tool for genetic dissection of complex traits.
Genomics 2001;74(1):21-35.
2001: Lee S H; Girard S; Macina D; Busà M; Zafer A; Belouchi A; Gros P; Vidal S M
Susceptibility to mouse cytomegalovirus is associated with deletion of an activating natural killer cell receptor of the C-type lectin superfamily.
Nature genetics 2001;28(1):42-5.
2001: Daoud R; Julien M; Gros P; Georges E
Major photoaffinity drug binding sites in multidrug resistance protein 1 (MRP1) are within transmembrane domains 10-11 and 16-17.
The Journal of biological chemistry 2001;276(15):12324-30.
2001: Kibar Z; Underhill D A; Canonne-Hergaux F; Gauthier S; Justice M J; Gros P
Identification of a new chemically induced allele (Lp(m1Jus)) at the loop-tail locus: morphology, histology, and genetic mapping.
Genomics 2001;72(3):331-7.
2001: Underhill D A; Vogan K J; Underhill T M; Gros P
Identification of a novel, alternatively spliced isoform and single nucleotide polymorphisms in the murine Pea-15 gene.
Mammalian genome : official journal of the International Mammalian Genome Society 2001;12(2):172-4.
2001: Canonne-Hergaux F; Levy J E; Fleming M D; Montross L K; Andrews N C; Gros P
Expression of the DMT1 (NRAMP2/DCT1) iron transporter in mice with genetic iron overload disorders.
Blood 2001;97(4):1138-40.
2000: Mitsos L M; Cardon L R; Fortin A; Ryan L; LaCourse R; North R J; Gros P
Genetic control of susceptibility to infection with Mycobacterium tuberculosis in mice.
Genes and immunity 2000;1(8):467-77.
2000: Daoud R; Kast C; Gros P; Georges E
Rhodamine 123 binds to multiple sites in the multidrug resistance protein (MRP1).
Biochemistry 2000;39(50):15344-52.
2000: Canonne-Hergaux F; Fleming M D; Levy J E; Gauthier S; Ralph T; Picard V; Andrews N C; Gros P
The Nramp2/DMT1 iron transporter is induced in the duodenum of microcytic anemia mk mice but is not properly targeted to the intestinal brush border.
Blood 2000;96(12):3964-70.
2000: Urbatsch I L; Julien M; Carrier I; Rousseau M E; Cayrol R; Gros P
Mutational analysis of conserved carboxylate residues in the nucleotide binding sites of P-glycoprotein.
Biochemistry 2000;39(46):14138-49.
2000: Jabado N; Jankowski A; Dougaparsad S; Picard V; Grinstein S; Gros P
Natural resistance to intracellular infections: natural resistance-associated macrophage protein 1 (Nramp1) functions as a pH-dependent manganese transporter at the phagosomal membrane.
The Journal of experimental medicine 2000;192(9):1237-48.
2000: Picard V; Govoni G; Jabado N; Gros P
Nramp 2 (DCT1/DMT1) expressed at the plasma membrane transports iron and other divalent cations into a calcein-accessible cytoplasmic pool.
The Journal of biological chemistry 2000;275(46):35738-45.
2000: Fortin A; Penman M; Stevenson M M; Krieger M; Gros P
Identification and characterization of naturally occurring variants of the macrophage scavenger receptor (SR-A).
Mammalian genome : official journal of the International Mammalian Genome Society 2000;11(9):779-85.
2000: Underhill D A; Vogan K J; Kibar Z; Morrison J; Rommens J; Gros P
Transcription mapping and expression analysis of candidate genes in the vicinity of the mouse Loop-tail mutation.
Mammalian genome : official journal of the International Mammalian Genome Society 2000;11(8):633-8.
2000: Kwan T; Loughrey H; Brault M; Gruenheid S; Urbatsch I L; Senior A E; Gros P
Functional analysis of a tryptophan-less P-glycoprotein: a tool for tryptophan insertion and fluorescence spectroscopy.
Molecular pharmacology 2000;58(1):37-47.
2000: Depatie C; Lee S H; Stafford A; Avner P; Belouchi A; Gros P; Vidal S M
Sequence-ready BAC contig, physical, and transcriptional map of a 2-Mb region overlapping the mouse chromosome 6 host-resistance locus Cmv1.
Genomics 2000;66(2):161-74.
2000: Daoud R; Desneves J; Deady L W; Tilley L; Scheper R J; Gros P; Georges E
The multidrug resistance protein is photoaffinity labeled by a quinoline-based drug at multiple sites.
Biochemistry 2000;39(20):6094-102.
2000: Julien M; Gros P
Nucleotide-induced conformational changes in P-glycoprotein and in nucleotide binding site mutants monitored by trypsin sensitivity.
Biochemistry 2000;39(15):4559-68.
2000: Sebastiani G; Leveque G; Larivière L; Laroche L; Skamene E; Gros P; Malo D
Cloning and characterization of the murine toll-like receptor 5 (Tlr5) gene: sequence and mRNA expression studies in Salmonella-susceptible MOLF/Ei mice.
Genomics 2000;64(3):230-40.
2000: Makui H; Roig E; Cole S T; Helmann J D; Gros P; Cellier M F
Identification of the Escherichia coli K-12 Nramp orthologue (MntH) as a selective divalent metal ion transporter.
Molecular microbiology 2000;35(5):1065-78.
2000: Gruenheid S; Gros P
Genetic susceptibility to intracellular infections: Nramp1, macrophage function and divalent cations transport.
Current opinion in microbiology 2000;3(1):43-8.
2000: Diez E; Yaraghi Z; MacKenzie A; Gros P
The neuronal apoptosis inhibitory protein (Naip) is expressed in macrophages and is modulated after phagocytosis and during intracellular infection with Legionella pneumophila.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(3):1470-7.
2000: Julien M; Kajiji S; Kaback R H; Gros P
Simple purification of highly active biotinylated P-glycoprotein: enantiomer-specific modulation of drug-stimulated ATPase activity.
Biochemistry 2000;39(1):75-85.
1999: Qureshi S T; Gros P; Malo D
The Lps locus: genetic regulation of host responses to bacterial lipopolysaccharide.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 1999;48(12):613-20.
1999: Underhill D A; Canfield V A; Dahl J P; Gros P; Levenson R
The Na,K-ATPase alpha4 gene (Atp1a4) encodes a ouabain-resistant alpha subunit and is tightly linked to the alpha2 gene (Atp1a2) on mouse chromosome 1.
Biochemistry 1999;38(45):14746-51.
1999: North R J; LaCourse R; Ryan L; Gros P
Consequence of Nramp1 deletion to Mycobacterium tuberculosis infection in mice.
Infection and immunity 1999;67(11):5811-4.
1999: Qureshi S T; Gros P; Malo D
Host resistance to infection: genetic control of lipopolysaccharide responsiveness by TOLL-like receptor genes.
Trends in genetics : TIG 1999;15(8):291-4.
1999: Canonne-Hergaux F; Gruenheid S; Govoni G; Gros P
The Nramp1 protein and its role in resistance to infection and macrophage function.
Proceedings of the Association of American Physicians 1999;111(4):283-9.
1999: Yaraghi Z; Diez E; Gros P; MacKenzie A
cDNA cloning and the 5'genomic organization of Naip2, a candidate gene for murine Legionella resistance.
Mammalian genome : official journal of the International Mammalian Genome Society 1999;10(7):761-3.
1999: Canonne-Hergaux F; Gruenheid S; Ponka P; Gros P
Cellular and subcellular localization of the Nramp2 iron transporter in the intestinal brush border and regulation by dietary iron.
Blood 1999;93(12):4406-17.
1999: Govoni G; Canonne-Hergaux F; Pfeifer C G; Marcus S L; Mills S D; Hackam D J; Grinstein S; Malo D; Finlay B B; Gros P
Functional expression of Nramp1 in vitro in the murine macrophage line RAW264.7.
Infection and immunity 1999;67(5):2225-32.
1999: Ruetz S; Brault M; Dalton W; Gros P
Functional interactions between synthetic alkyl phospholipids and the ABC transporters P-glycoprotein, Ste-6, MRP, and Pgh 1.
Biochemistry 1999;38(9):2860.
1999: Gruenheid S; Canonne-Hergaux F; Gauthier S; Hackam D J; Grinstein S; Gros P
The iron transport protein NRAMP2 is an integral membrane glycoprotein that colocalizes with transferrin in recycling endosomes.
The Journal of experimental medicine 1999;189(5):831-41.
1999: Ruetz S; Delling U; Brault M; Schurr E; Gros P
The pfmdr1 gene of Plasmodium falciparum confers cellular resistance to antimalarial drugs in yeast cells.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(4):1810.
1999: Qureshi S T; Larivière L; Leveque G; Clermont S; Moore K J; Gros P; Malo D
Endotoxin-tolerant mice have mutations in Toll-like receptor 4 (Tlr4)
The Journal of experimental medicine 1999;189(4):615-25.
1999: Ruetz S; Brault M; Kast C; Hemenway C; Heitman J; Grant C E; Cole S P; Deeley R G; Gros P
Functional expression of the multidrug resistance-associated protein in the yeast Saccharomyces cerevisiae.
The Journal of biological chemistry 1999;274(4):2592.
1999: Underhill D A; Mullick A; Groulx N; Beatty B G; Gros P
Physical delineation of a 700-kb region overlapping the Looptail mutation on mouse chromosome 1.
Genomics 1999;55(2):185-93.
1998: Fortin A S; Underhill D A; Gros P
Helix 2 of the paired domain plays a key role in the regulation of DNA-binding by the Pax-3 homeodomain.
Nucleic acids research 1998;26(20):4574-81.
1998: Gros P; Beaudet L; Urbatsch I L
Yeast as an expression system for the study of P-glycoprotein and other ABC transporters.
Acta physiologica Scandinavica. Supplementum 1998;643():219-25.
1998: Reece M; Prawitt D; Landers J; Kast C; Gros P; Housman D; Zabel B U; Pelletier J
Functional characterization of ORCTL2--an organic cation transporter expressed in the renal proximal tubules.
FEBS letters 1998;433(3):245-50.
1998: Govoni G; Gros P
Macrophage NRAMP1 and its role in resistance to microbial infections.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 1998;47(7):277-84.
1998: Hackam D J; Rotstein O D; Zhang W; Gruenheid S; Gros P; Grinstein S
Host resistance to intracellular infection: mutation of natural resistance-associated macrophage protein 1 (Nramp1) impairs phagosomal acidification.
The Journal of experimental medicine 1998;188(2):351-64.
1998: Beaudet L; Urbatsch I L; Gros P
Mutations in the nucleotide-binding sites of P-glycoprotein that affect substrate specificity modulate substrate-induced adenosine triphosphatase activity.
Biochemistry 1998;37(25):9073-82.
1998: Urbatsch I L; Beaudet L; Carrier I; Gros P
Mutations in either nucleotide-binding site of P-glycoprotein (Mdr3) prevent vanadate trapping of nucleotide at both sites.
Biochemistry 1998;37(13):4592-602.
1998: Kwan T; Gros P
Mutational analysis of the P-glycoprotein first intracellular loop and flanking transmembrane domains.
Biochemistry 1998;37(10):3337-50.
1998: Kast C; Gros P
Epitope insertion favors a six transmembrane domain model for the carboxy-terminal portion of the multidrug resistance-associated protein.
Biochemistry 1998;37(8):2305-13.
1998: Malik N; Canfield V; Sanchez-Watts G; Watts A G; Scherer S; Beatty B G; Gros P; Levenson R
Structural organization and chromosomal localization of the human Na,K-ATPase beta 3 subunit gene and pseudogene.
Mammalian genome : official journal of the International Mammalian Genome Society 1998;9(2):136-43.
1998: Sebastiani G; Olien L; Gauthier S; Skamene E; Morgan K; Gros P; Malo D
Mapping of genetic modulators of natural resistance to infection with Salmonella typhimurium in wild-derived mice.
Genomics 1998;47(2):180-6.
1998: Beaudet L; Gros P
Mutational analysis of P-glycoprotein in yeast Saccharomyces cerevisiae.
Methods in enzymology 1998;292():414-27.
1998: Beaudet L; Urbatsch I L; Gros P
High-level expression of mouse Mdr3 P-glycoprotein in yeast Pichia pastoris and characterization of ATPase activity.
Methods in enzymology 1998;292():397-413.
1997: Fortin A; Belouchi A; Tam M F; Cardon L; Skamene E; Stevenson M M; Gros P
Genetic control of blood parasitaemia in mouse malaria maps to chromosome 8.
Nature genetics 1997;17(4):382-3.
1997: Pinner E; Gruenheid S; Raymond M; Gros P
Functional complementation of the yeast divalent cation transporter family SMF by NRAMP2, a member of the mammalian natural resistance-associated macrophage protein family.
The Journal of biological chemistry 1997;272(46):28933-8.
1997: Vogan K J; Gros P
The C-terminal subdomain makes an important contribution to the DNA binding activity of the Pax-3 paired domain.
The Journal of biological chemistry 1997;272(45):28289-95.
1997: Kast C; Gros P
Topology mapping of the amino-terminal half of multidrug resistance-associated protein by epitope insertion and immunofluorescence.
The Journal of biological chemistry 1997;272(42):26479-87.
1997: Fortin A S; Underhill D A; Gros P
Reciprocal effect of Waardenburg syndrome mutations on DNA binding by the Pax-3 paired domain and homeodomain.
Human molecular genetics 1997;6(11):1781-90.
1997: Diez E; Beckers M C; Ernst E; DiDonato C J; Simard L R; Morissette C; Gervais F; Yoshida S I; Gros P
Genetic and physical mapping of the mouse host resistance locus Lgn1.
Mammalian genome : official journal of the International Mammalian Genome Society 1997;8(9):682-5.
1997: Govoni G; Gauthier S; Billia F; Iscove N N; Gros P
Cell-specific and inducible Nramp1 gene expression in mouse macrophages in vitro and in vivo.
Journal of leukocyte biology 1997;62(2):277-86.
1997: Ruetz S; Brault M; Dalton W; Gros P
Functional interactions between synthetic alkyl phospholipids and the ABC transporters P-glycoprotein, Ste-6, MRP, and Pgh 1.
Biochemistry 1997;36(26):8180-8.
1997: Underhill D A; Gros P
The paired-domain regulates DNA binding by the homeodomain within the intact Pax-3 protein.
The Journal of biological chemistry 1997;272(22):14175-82.
1997: Belouchi A; Kwan T; Gros P
Cloning and characterization of the OsNramp family from Oryza sativa, a new family of membrane proteins possibly implicated in the transport of metal ions.
Plant molecular biology 1997;33(6):1085-92.
1997: Beckers M C; Ernst E; Diez E; Morissette C; Gervais F; Hunter K; Housman D; Yoshida S; Skamene E; Gros P
High-resolution linkage map of mouse chromosome 13 in the vicinity of the host resistance locus Lgn1.
Genomics 1997;39(3):254-63.
1997: Gruenheid S; Pinner E; Desjardins M; Gros P
Natural resistance to infection with intracellular pathogens: the Nramp1 protein is recruited to the membrane of the phagosome.
The Journal of experimental medicine 1997;185(4):717-30.
1997: Depatie C; Muise E; Lepage P; Gros P; Vidal S M
High-resolution linkage map in the proximity of the host resistance locus Cmv1.
Genomics 1997;39(2):154-63.
1997: Cellier M; Shustik C; Dalton W; Rich E; Hu J; Malo D; Schurr E; Gros P
Expression of the human NRAMP1 gene in professional primary phagocytes: studies in blood cells and in HL-60 promyelocytic leukemia.
Journal of leukocyte biology 1997;61(1):96-105.
1996: Vogan K J; Underhill D A; Gros P
An alternative splicing event in the Pax-3 paired domain identifies the linker region as a key determinant of paired domain DNA-binding activity.
Molecular and cellular biology 1996;16(12):6677-86.
1996: Malik N; Canfield V A; Beckers M C; Gros P; Levenson R
Identification of the mammalian Na,K-ATPase 3 subunit.
The Journal of biological chemistry 1996;271(37):22754-8.
1996: Ruetz S; Delling U; Brault M; Schurr E; Gros P
The pfmdr1 gene of Plasmodium falciparum confers cellular resistance to antimalarial drugs in yeast cells.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(18):9942-7.
1996: Beckers M C; Ernst E; Belcher S; Howe J; Levenson R; Gros P
A new sodium channel alpha-subunit gene (Scn9a) from Schwann cells maps to the Scn1a, Scn2a, Scn3a cluster of mouse chromosome 2.
Genomics 1996;36(1):202-5.
1996: Govoni G; Vidal S; Gauthier S; Skamene E; Malo D; Gros P
The Bcg/Ity/Lsh locus: genetic transfer of resistance to infections in C57BL/6J mice transgenic for the Nramp1 Gly169 allele.
Infection and immunity 1996;64(8):2923-9.
1996: Cellier M; Belouchi A; Gros P
Resistance to intracellular infections: comparative genomic analysis of Nramp.
Trends in genetics : TIG 1996;12(6):201-4.
1996: Kast C; Canfield V; Levenson R; Gros P
Transmembrane organization of mouse P-glycoprotein determined by epitope insertion and immunofluorescence.
The Journal of biological chemistry 1996;271(16):9240-8.
1996: Hanna M; Brault M; Kwan T; Kast C; Gros P
Mutagenesis of transmembrane domain 11 of P-glycoprotein by alanine scanning.
Biochemistry 1996;35(11):3625-35.
1996: Qureshi S T; Larivière L; Sebastiani G; Clermont S; Skamene E; Gros P; Malo D
A high-resolution map in the chromosomal region surrounding the Lps locus.
Genomics 1996;31(3):283-94.
1996: Hu J; Bumstead N; Skamene E; Gros P; Malo D
Structural organization, sequence, and expression of the chicken NRAMP1 gene encoding the natural resistance-associated macrophage protein 1.
DNA and cell biology 1996;15(2):113-23.
1996: Ruetz S; Brault M; Kast C; Hemenway C; Heitman J; Grant C E; Cole S P; Deeley R G; Gros P
Functional expression of the multidrug resistance-associated protein in the yeast Saccharomyces cerevisiae.
The Journal of biological chemistry 1996;271(8):4154-60.
1995: Belouchi A; Cellier M; Kwan T; Saini H S; Leroux G; Gros P
The macrophage-specific membrane protein Nramp controlling natural resistance to infections in mice has homologues expressed in the root system of plants.
Plant molecular biology 1995;29(6):1181-96.
1995: Hu J; Bumstead N; Burke D; Ponce de León F A; Skamene E; Gros P; Malo D
Genetic and physical mapping of the natural resistance-associated macrophage protein 1 (NRAMP1) in chicken.
Mammalian genome : official journal of the International Mammalian Genome Society 1995;6(11):809-15.
1995: Mullick A; Groulx N; Trasler D; Gros P
Nhlh1, a basic helix-loop-helix transcription factor, is very tightly linked to the mouse looptail (Lp) mutation.
Mammalian genome : official journal of the International Mammalian Genome Society 1995;6(10):700-4.
1995: Ruetz S; Gros P
Enhancement of Mdr2-mediated phosphatidylcholine translocation by the bile salt taurocholate. Implications for hepatic bile formation.
The Journal of biological chemistry 1995;270(43):25388-95.
1995: Vidal S; Gros P; Skamene E
Natural resistance to infection with intracellular parasites: molecular genetics identifies Nramp1 as the Bcg/Ity/Lsh locus.
Journal of leukocyte biology 1995;58(4):382-90.
1995: Cellier M; Privé G; Belouchi A; Kwan T; Rodrigues V; Chia W; Gros P
Nramp defines a family of membrane proteins.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(22):10089-93.
1995: Vidal S; Tremblay M L; Govoni G; Gauthier S; Sebastiani G; Malo D; Skamene E; Olivier M; Jothy S; Gros P
The Ity/Lsh/Bcg locus: natural resistance to infection with intracellular parasites is abrogated by disruption of the Nramp1 gene.
The Journal of experimental medicine 1995;182(3):655-66.
1995: Beckers M C; Yoshida S; Morgan K; Skamene E; Gros P
Natural resistance to infection with Legionella pneumophila: chromosomal localization of the Lgn1 susceptibility gene.
Mammalian genome : official journal of the International Mammalian Genome Society 1995;6(8):540-5.
1995: Lepage P; Underhill D A; Gros P
Activation of a MMTV/mdr3 fusion transcript from a cryptic viral promoter is stimulated by mdr-derived sequences located in intron I.
Virology 1995;210(2):244-53.
1995: Beaudet L; Gros P
Functional dissection of P-glycoprotein nucleotide-binding domains in chimeric and mutant proteins. Modulation of drug resistance profiles.
The Journal of biological chemistry 1995;270(29):17159-70.
1995: Govoni G; Vidal S; Cellier M; Lepage P; Malo D; Gros P
Genomic structure, promoter sequence, and induction of expression of the mouse Nramp1 gene in macrophages.
Genomics 1995;27(1):9-19.
1995: Underhill D A; Vogan K J; Gros P
Analysis of the mouse Splotch-delayed mutation indicates that the Pax-3 paired domain can influence homeodomain DNA-binding activity.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(9):3692-6.
1995: Liu J; Fujiwara T M; Buu N T; Sánchez F O; Cellier M; Paradis A J; Frappier D; Skamene E; Gros P; Morgan K
Identification of polymorphisms and sequence variants in the human homologue of the mouse natural resistance-associated macrophage protein gene.
American journal of human genetics 1995;56(4):845-53.
1995: Vidal S; Belouchi A M; Cellier M; Beatty B; Gros P
Cloning and characterization of a second human NRAMP gene on chromosome 12q13.
Mammalian genome : official journal of the International Mammalian Genome Society 1995;6(4):224-30.
1995: Mullick A; Trasler D; Gros P
High-resolution linkage map in the vicinity of the Lp locus.
Genomics 1995;26(3):479-88.
1995: Kast C; Canfield V; Levenson R; Gros P
Membrane topology of P-glycoprotein as determined by epitope insertion: transmembrane organization of the N-terminal domain of mdr3.
Biochemistry 1995;34(13):4402-11.
1995: Qureshi S T; Gros P; Letarte M; Malo D
The murine endoglin gene (Eng) maps to chromosome 2.
Genomics 1995;26(1):165-6.
1995: Liu J; Stanton V P; Fujiwara T M; Wang J X; Rezonzew R; Crumley M J; Morgan K; Gros P; Housman D; Schurr E
Large-scale cloning of human chromosome 2-specific yeast artificial chromosomes (YACs) using an interspersed repetitive sequences (IRS)-PCR approach.
Genomics 1995;26(2):178-91.
1995: Sebastiani G; Durocher D; Gros P; Nemer M; Malo D
Localization of the Catf1 transcription factor gene to mouse chromosome 19.
Mammalian genome : official journal of the International Mammalian Genome Society 1995;6(2):147-8.
1995: Tang-Wai D F; Kajiji S; DiCapua F; de Graaf D; Roninson I B; Gros P
Human (MDR1) and mouse (mdr1, mdr3) P-glycoproteins can be distinguished by their respective drug resistance profiles and sensitivity to modulators.
Biochemistry 1995;34(1):32-9.
1995: Gruenheid S; Cellier M; Vidal S; Gros P
Identification and characterization of a second mouse Nramp gene.
Genomics 1995;25(2):514-25.
1995: Buu N T; Cellier M; Gros P; Schurr E
Identification of a highly polymorphic length variant in the 3'UTR of NRAMP1.
Immunogenetics 1995;42(5):428-9.
1994: Cellier M; Govoni G; Vidal S; Kwan T; Groulx N; Liu J; Sanchez F; Skamene E; Schurr E; Gros P
Human natural resistance-associated macrophage protein: cDNA cloning, chromosomal mapping, genomic organization, and tissue-specific expression.
The Journal of experimental medicine 1994;180(5):1741-52.
1994: Buschman E; Gros P
The inability of the mouse mdr2 gene to confer multidrug resistance is linked to reduced drug binding to the protein.
Cancer research 1994;54(18):4892-8.
1994: Malo D; Vogan K; Vidal S; Hu J; Cellier M; Schurr E; Fuks A; Bumstead N; Morgan K; Gros P
Haplotype mapping and sequence analysis of the mouse Nramp gene predict susceptibility to infection with intracellular parasites.
Genomics 1994;23(1):51-61.
1994: Ruetz S; Gros P
A mechanism for P-glycoprotein action in multidrug resistance: are we there yet?
Trends in pharmacological sciences 1994;15(7):260-3.
1994: Ruetz S; Gros P
Phosphatidylcholine translocase: a physiological role for the mdr2 gene.
Cell 1994;77(7):1071-81.
1994: Kajiji S; Dreslin J A; Grizzuti K; Gros P
Structurally distinct MDR modulators show specific patterns of reversal against P-glycoproteins bearing unique mutations at serine939/941.
Biochemistry 1994;33(17):5041-8.
1994: Ruetz S; Gros P
Functional expression of P-glycoproteins in secretory vesicles.
The Journal of biological chemistry 1994;269(16):12277-84.
1994: van Es H H; Karcz S; Chu F; Cowman A F; Vidal S; Gros P; Schurr E
Expression of the plasmodial pfmdr1 gene in mammalian cells is associated with increased susceptibility to chloroquine.
Molecular and cellular biology 1994;14(4):2419-28.
1994: Epstein D J; Bardeesy N; Vidal S; Malo D; Weith A; Vekemans M; Gros P
Characterization of a region-specific library of microclones in the vicinity of the Bcg and splotch loci on mouse chromosome 1.
Genomics 1994;19(1):163-6.
1994: Raymond M; Ruetz S; Thomas D Y; Gros P
Functional expression of P-glycoprotein in Saccharomyces cerevisiae confers cellular resistance to the immunosuppressive and antifungal agent FK520.
Molecular and cellular biology 1994;14(1):277-86.
1994: Buschman E; Lepage P; Gros P
P-glycoprotein homologues.
Cancer treatment and research 1994;73():17-39.
1993: Lepage P; Devault A; Gros P
Activation of the mouse mdr3 gene by insertion of retroviruses in multidrug-resistant P388 tumor cells.
Molecular and cellular biology 1993;13(12):7380-92.
1993: Ruetz S; Raymond M; Gros P
Functional expression of P-glycoprotein encoded by the mouse mdr3 gene in yeast cells.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(24):11588-92.
1993: Vogan K; Bernstein M; Leclerc J M; Brisson L; Brossard J; Brodeur G M; Pelletier J; Gros P
Absence of p53 gene mutations in primary neuroblastomas.
Cancer research 1993;53(21):5269-73.
1993: Malo D; Gros P; Bergmann A; Trask B; Mohrenweiser H W; Canfield V A; Levenson R
Genes encoding the H,K-ATPase alpha and Na,K-ATPase alpha 3 subunits are linked on mouse chromosome 7 and human chromosome 19.
Mammalian genome : official journal of the International Mammalian Genome Society 1993;4(11):644-9.
1993: Malo D; Vidal S; Lieman J H; Ward D C; Gros P
Physical delineation of the minimal chromosomal segment encompassing the murine host resistance locus Bcg.
Genomics 1993;17(3):667-75.
1993: Dhir R; Grizzuti K; Kajiji S; Gros P
Modulatory effects on substrate specificity of independent mutations at the serine939/941 position in predicted transmembrane domain 11 of P-glycoproteins.
Biochemistry 1993;32(36):9492-9.
1993: Vogan K J; Epstein D J; Trasler D G; Gros P
The splotch-delayed (Spd) mouse mutant carries a point mutation within the paired box of the Pax-3 gene.
Genomics 1993;17(2):364-9.
1993: Malo D; Vidal S M; Hu J; Skamene E; Gros P
High-resolution linkage map in the vicinity of the host resistance locus Bcg.
Genomics 1993;16(3):655-63.
1993: Tang-Wai D F; Brossi A; Arnold L D; Gros P
The nitrogen of the acetamido group of colchicine modulates P-glycoprotein-mediated multidrug resistance.
Biochemistry 1993;32(25):6470-6.
1993: Vidal S M; Malo D; Vogan K; Skamene E; Gros P
Natural resistance to infection with intracellular parasites: isolation of a candidate for Bcg.
Cell 1993;73(3):469-85.
1993: Lepage P; Raymond M; Nepveu A; Gros P
Transcriptional activation of the mouse mdr3 gene coincides with the appearance of novel transcription initiation sites in multidrug-resistant P388 tumor cells.
Cancer research 1993;53(7):1657-64.
1993: Kajiji S; Talbot F; Grizzuti K; Van Dyke-Phillips V; Agresti M; Safa A R; Gros P
Functional analysis of P-glycoprotein mutants identifies predicted transmembrane domain 11 as a putative drug binding site.
Biochemistry 1993;32(16):4185-94.
1993: Epstein D J; Vogan K J; Trasler D G; Gros P
A mutation within intron 3 of the Pax-3 gene produces aberrantly spliced mRNA transcripts in the splotch (Sp) mouse mutant.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(2):532-6.
1993: Bruening W; Gros P; Sato T; Stanimir J; Nakamura Y; Housman D; Pelletier J
Analysis of the 11p13 Wilms' tumor suppressor gene (WT1) in ovarian tumors.
Cancer investigation 1993;11(4):393-9.
1993: Gros P; Buschman E
The multidrug resistance transport protein: identification of functional domains.
Society of General Physiologists series 1993;48():95-117.
1993: Gros P; Buschman E
The mouse multidrug resistance gene family: structural and functional analysis.
International review of cytology 1993;137C():169-97.
1992: Buschman E; Arceci R J; Croop J M; Che M; Arias I M; Housman D E; Gros P
mdr2 encodes P-glycoprotein expressed in the bile canalicular membrane as determined by isoform-specific antibodies.
The Journal of biological chemistry 1992;267(25):18093-9.
1992: Vidal S M; Epstein D J; Malo D; Weith A; Vekemans M; Gros P
Identification and mapping of six microdissected genomic DNA probes to the proximal region of mouse chromosome 1.
Genomics 1992;14(1):32-7.
1992: Dhir R; Gros P
Functional analysis of chimeric proteins constructed by exchanging homologous domains of two P-glycoproteins conferring distinct drug resistance profiles.
Biochemistry 1992;31(26):6103-10.
1992: Gros P; Talbot F; Tang-Wai D; Bibi E; Kaback H R
Lipophilic cations: a group of model substrates for the multidrug-resistance transporter.
Biochemistry 1992;31(7):1992-8.
1992: Mancino F; Vekemans M; Trasler D G; Gros P
Segregation analysis reveals tight genetic linkage between the spontaneously arising neural tube defect gene splotch (Sp) and Pax-3 in an intraspecific mouse backcross.
Cytogenetics and cell genetics 1992;61(2):143-5.
1991: Epstein D J; Vekemans M; Gros P
Splotch (Sp2H), a mutation affecting development of the mouse neural tube, shows a deletion within the paired homeodomain of Pax-3.
Cell 1991;67(4):767-74.
1991: Gros P; Dhir R; Croop J; Talbot F
A single amino acid substitution strongly modulates the activity and substrate specificity of the mouse mdr1 and mdr3 drug efflux pumps.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(16):7289-93.
1991: Malo D; Schurr E; Dorfman J; Canfield V; Levenson R; Gros P
Three brain sodium channel alpha-subunit genes are clustered on the proximal segment of mouse chromosome 2.
Genomics 1991;10(3):666-72.
1991: Malo D; Schurr E; Epstein D J; Vekemans M; Skamene E; Gros P
The host resistance locus Bcg is tightly linked to a group of cytoskeleton-associated protein genes that include villin and desmin.
Genomics 1991;10(2):356-64.
1991: Epstein D J; Malo D; Vekemans M; Gros P
Molecular characterization of a deletion encompassing the splotch mutation on mouse chromosome 1.
Genomics 1991;10(1):89-93.
1991: Dorfman J; Lazaris-Karatzas A; Malo D; Sonenberg N; Gros P
Chromosomal assignment of one of the mammalian translation initiation factor eIF-4E genes.
Genomics 1991;9(4):785-8.
1991: Schurr E; Malo D; Radzioch D; Buschman E; Morgan K; Gros P; Skamene E
Genetic control of innate resistance to mycobacterial infections.
Immunology today 1991;12(3):A42-5.
1991: Buschman E; Gros P
Functional analysis of chimeric genes obtained by exchanging homologous domains of the mouse mdr1 and mdr2 genes.
Molecular and cellular biology 1991;11(2):595-603.
1991: Schurr E; Radzioch D; Malo D; Gros P; Skamene E
Molecular genetics of inherited susceptibility to intracellular parasites.
Behring Institute Mitteilungen 1991;(88):1-12.
1991: Schurr E; Skamene E; Gros P
Mapping of the gene coding for the muscle protein nebulin (Neb) to the proximal region of mouse chromosome 2.
Cytogenetics and cell genetics 1991;57(4):214-6.
1991: Gros P; Shustik C
Multidrug resistance: a novel class of membrane-associated transport proteins is identified.
Cancer investigation 1991;9(5):563-9.
1991: Canfield V A; Okamato C T; Chow D; Dorfman J; Gros P; Forte J G; Levenson R
Identification and characterization of a gene for the H,K-ATPase beta-subunit.
Society of General Physiologists series 1991;46():89-98.
1990: Raymond M; Gros P
Cell-specific activity of cis-acting regulatory elements in the promoter of the mouse multidrug resistance gene mdr1.
Molecular and cellular biology 1990;10(11):6036-40.
1990: Schurr E; Skamene E; Morgan K; Chu M L; Gros P
Mapping of Col3a1 and Col6a3 to proximal murine chromosome 1 identifies conserved linkage of structural protein genes between murine chromosome 1 and human chromosome 2q.
Genomics 1990;8(3):477-86.
1990: Canfield V A; Okamoto C T; Chow D; Dorfman J; Gros P; Forte J G; Levenson R
Cloning of the H,K-ATPase beta subunit. Tissue-specific expression, chromosomal assignment, and relationship to Na,K-ATPase beta subunits.
The Journal of biological chemistry 1990;265(32):19878-84.
1990: Schurr E; Buschman E; Malo D; Gros P; Skamene E
Immunogenetics of mycobacterial infections: mouse-human homologies.
The Journal of infectious diseases 1990;161(4):634-9.
1990: Malo D; Schurr E; Levenson R; Gros P
Assignment of Na,K-ATPase beta 2-subunit gene (Atpb-2) to mouse chromosome 11.
Genomics 1990;6(4):697-9.
1990: Devault A; Gros P
Two members of the mouse mdr gene family confer multidrug resistance with overlapping but distinct drug specificities.
Molecular and cellular biology 1990;10(4):1652-63.
1990: Raymond M; Rose E; Housman D E; Gros P
Physical mapping, amplification, and overexpression of the mouse mdr gene family in multidrug-resistant cells.
Molecular and cellular biology 1990;10(4):1642-51.
1990: Dhir R; Buschman E; Gros P
Structural and functional characterization of the mouse multidrug resistance gene family.
Bulletin du cancer 1990;77(11):1125-9.
1989: Azzaria M; Schurr E; Gros P
Discrete mutations introduced in the predicted nucleotide-binding sites of the mdr1 gene abolish its ability to confer multidrug resistance.
Molecular and cellular biology 1989;9(12):5289-97.
1989: Gros P; Malo D
A reverse genetics approach to Bcg/Ity/Lsh gene cloning.
Research in immunology 1989;140(8):774-7.
1989: Raymond M; Gros P
Mammalian multidrug-resistance gene: correlation of exon organization with structural domains and duplication of an ancestral gene.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(17):6488-92.
1989: Hammond J R; Johnstone R M; Gros P
Enhanced efflux of [3H]vinblastine from Chinese hamster ovary cells transfected with a full-length complementary DNA clone for the mdr1 gene.
Cancer research 1989;49(14):3867-71.
1989: Schurr E; Skamene E; Forget A; Gros P
Linkage analysis of the Bcg gene on mouse chromosome 1. Identification of a tightly linked marker.
Journal of immunology (Baltimore, Md. : 1950) 1989;142(12):4507-13.
1989: Schurr E; Raymond M; Bell J C; Gros P
Characterization of the multidrug resistance protein expressed in cell clones stably transfected with the mouse mdr1 cDNA.
Cancer research 1989;49(10):2729-33.
1989: Croop J M; Raymond M; Haber D; Devault A; Arceci R J; Gros P; Housman D E
The three mouse multidrug resistance (mdr) genes are expressed in a tissue-specific manner in normal mouse tissues.
Molecular and cellular biology 1989;9(3):1346-50.
1989: Schurr E; Henthorn P S; Harris H; Skamene E; Gros P
Localization of two alkaline phosphatase genes to the proximal region of mouse chromosome 1.
Cytogenetics and cell genetics 1989;52(1-2):65-7.
1988: Gros P; Raymond M; Bell J; Housman D
Cloning and characterization of a second member of the mouse mdr gene family.
Molecular and cellular biology 1988;8(7):2770-8.
1987: Croop J M; Guild B C; Gros P; Housman D E
Genetics of multidrug resistance: relationship of a cloned gene to the complete multidrug resistant phenotype.
Cancer research 1987;47(22):5982-8.

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