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Carol Gross
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12
Lu, Chi Zen
9
Gruber, Tanja
9
Rhodius, Virgil
7
Alba, Benjamin
6
Sharp, Meghan M.
5
Erickson, James W.
5
Herman, Christophe
5
Landick, Robert
4
Grigorova, Irina
4
Dombroski, Alicia
4
Guisbert, Eric
4
Siegele, Deborah
4
Young, Brian
3
Zhong, Hong Ji
3
Koo, Byoung-Mo
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All Publications
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2009: Mutalik Vivek K; Nonaka Gen; Ades Sarah E; Rhodius Virgil A; Gross Carol A
Promoter strength properties of the complete sigma E regulon of Escherichia coli and Salmonella enterica.
Journal of bacteriology 2009;191(23):7279-87.
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2009: Koo Byoung-Mo; Rhodius Virgil A; Nonaka Gen; deHaseth Pieter L; Gross Carol A
Reduced capacity of alternative sigmas to melt promoters ensures stringent promoter recognition.
Genes & development 2009;23(20):2426-36.
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2009: Koo Byoung-Mo; Rhodius Virgil A; Campbell Elizabeth A; Gross Carol A
Dissection of recognition determinants of Escherichia coli sigma32 suggests a composite -10 region with an 'extended -10' motif and a core -10 element.
Molecular microbiology 2009;72(4):815-29.
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2009: Koo Byoung-Mo; Rhodius Virgil A; Campbell Elizabeth A; Gross Carol A
Mutational analysis of Escherichia coli sigma28 and its target promoters reveals recognition of a composite -10 region, comprised of an 'extended -10' motif and a core -10 element.
Molecular microbiology 2009;72(4):830-43.
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2009: Ahuja Nidhi; Korkin Dmitry; Chaba Rachna; Cezairliyan Brent O; Sauer Robert T; Kim Kyeong Kyu; Gross Carol A
Analyzing the interaction of RseA and RseB, the two negative regulators of the sigmaE envelope stress response, using a combined bioinformatic and experimental strategy.
The Journal of biological chemistry 2009;284(8):5403-13.
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2008: Typas Athanasios; Nichols Robert J; Siegele Deborah A; Shales Michael; Collins Sean R; Lim Bentley; Braberg Hannes; Yamamoto Natsuko; Takeuchi Rikiya; Wanner Barry L; Mori Hirotada; Weissman Jonathan S; Krogan Nevan J; Gross Carol A
High-throughput, quantitative analyses of genetic interactions in E. coli.
Nature methods 2008;5(9):781-7.
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2008: Guisbert Eric; Yura Takashi; Rhodius Virgil A; Gross Carol A
Convergence of molecular, modeling, and systems approaches for an understanding of the Escherichia coli heat shock response.
Microbiology and molecular biology reviews : MMBR 2008;72(3):545-54.
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2007: Yura Takashi; Guisbert Eric; Poritz Mark; Lu Chi Zen; Campbell Elizabeth; Gross Carol A
Analysis of sigma32 mutants defective in chaperone-mediated feedback control reveals unexpected complexity of the heat shock response.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(45):17638-43.
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2007: Guisbert Eric; Rhodius Virgil A; Ahuja Nidhi; Witkin Emily; Gross Carol A
Hfq modulates the sigmaE-mediated envelope stress response and the sigma32-mediated cytoplasmic stress response in Escherichia coli.
Journal of bacteriology 2007;189(5):1963-73.
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2007: Chaba Rachna; Grigorova Irina L; Flynn Julia M; Baker Tania A; Gross Carol A
Design principles of the proteolytic cascade governing the sigmaE-mediated envelope stress response in Escherichia coli: keys to graded, buffered, and rapid signal transduction.
Genes & development 2007;21(1):124-36.
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2006: Nonaka Gen; Blankschien Matthew; Herman Christophe; Gross Carol A; Rhodius Virgil A
Regulon and promoter analysis of the E. coli heat-shock factor, sigma32, reveals a multifaceted cellular response to heat stress.
Genes & development 2006;20(13):1776-89.
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2006: Grigorova Irina L; Phleger Naum J; Mutalik Vivek K; Gross Carol A
Insights into transcriptional regulation and sigma competition from an equilibrium model of RNA polymerase binding to DNA.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(14):5332-7.
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2006: Rhodius Virgil A; Suh Won Chul; Nonaka Gen; West Joyce; Gross Carol A
Conserved and variable functions of the sigmaE stress response in related genomes.
PLoS biology 2006;4(1):e2.
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2005: Onufryk Christina; Crouch Marie-Laure; Fang Ferric C; Gross Carol A
Characterization of six lipoproteins in the sigmaE regulon.
Journal of bacteriology 2005;187(13):4552-61.
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2005: Berghöfer-Hochheimer Yvonne; Lu Chi Zen; Gross Carol A
Altering the interaction between sigma70 and RNA polymerase generates complexes with distinct transcription-elongation properties.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(4):1157-62.
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2004: Guisbert Eric; Herman Christophe; Lu Chi Zen; Gross Carol A
A chaperone network controls the heat shock response in E. coli.
Genes & development 2004;18(22):2812-21.
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2004: Grigorova Irina L; Chaba Rachna; Zhong Hong Ji; Alba Benjamin M; Rhodius Virgil; Herman Christophe; Gross Carol A
Fine-tuning of the Escherichia coli sigmaE envelope stress response relies on multiple mechanisms to inhibit signal-independent proteolysis of the transmembrane anti-sigma factor, RseA.
Genes & development 2004;18(21):2686-97.
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2004: Geszvain Kati; Gruber Tanja M; Mooney Rachel A; Gross Carol A; Landick Robert
A hydrophobic patch on the flap-tip helix of E.coli RNA polymerase mediates sigma(70) region 4 function.
Journal of molecular biology 2004;343(3):569-87.
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2004: Alba Benjamin M; Gross Carol A
Regulation of the Escherichia coli sigma-dependent envelope stress response.
Molecular microbiology 2004;52(3):613-9.
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2004: Young Brian A; Gruber Tanja M; Gross Carol A
Minimal machinery of RNA polymerase holoenzyme sufficient for promoter melting.
Science (New York, N.Y.) 2004;303(5662):1382-4.
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2003: Campbell Elizabeth A; Tupy Jonathan L; Gruber Tanja M; Wang Sheng; Sharp Meghan M; Gross Carol A; Darst Seth A
Crystal structure of Escherichia coli sigmaE with the cytoplasmic domain of its anti-sigma RseA.
Molecular cell 2003;11(4):1067-78.
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2003: Walsh Nathan P; Alba Benjamin M; Bose Baundauna; Gross Carol A; Sauer Robert T
OMP peptide signals initiate the envelope-stress response by activating DegS protease via relief of inhibition mediated by its PDZ domain.
Cell 2003;113(1):61-71.
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2003: Ades Sarah E; Grigorova Irina L; Gross Carol A
Regulation of the alternative sigma factor sigma(E) during initiation, adaptation, and shutoff of the extracytoplasmic heat shock response in Escherichia coli.
Journal of bacteriology 2003;185(8):2512-9.
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2003: Herman Christophe; Prakash Sumit; Lu Chi Zen; Matouschek Andreas; Gross Carol A
Lack of a robust unfoldase activity confers a unique level of substrate specificity to the universal AAA protease FtsH.
Molecular cell 2003;11(3):659-69.
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2003: Gruber Tanja M; Gross Carol A
Assay of Escherichia coli RNA polymerase: sigma-core interactions.
Methods in enzymology 2003;370():206-12.
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2003: Gruber Tanja M; Gross Carol A
Multiple sigma subunits and the partitioning of bacterial transcription space.
Annual review of microbiology 2003;57():441-66.
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2002: Wang Jue D; Herman Christophe; Tipton Kimberly A; Gross Carol A; Weissman Jonathan S
Directed evolution of substrate-optimized GroEL/S chaperonins.
Cell 2002;111(7):1027-39.
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2002: Alba Benjamin M; Leeds Jennifer A; Onufryk Christina; Lu Chi Zen; Gross Carol A
DegS and YaeL participate sequentially in the cleavage of RseA to activate the sigma(E)-dependent extracytoplasmic stress response.
Genes & development 2002;16(16):2156-68.
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2002: Young Brian A; Gruber Tanja M; Gross Carol A
Views of transcription initiation.
Cell 2002;109(4):417-20.
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2001: Chan C L; Gross C A
The anti-initial transcribed sequence, a portable sequence that impedes promoter escape, requires sigma70 for function.
The Journal of biological chemistry 2001;276(41):38201-9.
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2001: Gruber T M; Markov D; Sharp M M; Young B A; Lu C Z; Zhong H J; Artsimovitch I; Geszvain K M; Arthur T M; Burgess R R; Landick R; Severinov K; Gross C A
Binding of the initiation factor sigma(70) to core RNA polymerase is a multistep process.
Molecular cell 2001;8(1):21-31.
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2001: Alba B M; Zhong H J; Pelayo J C; Gross C A
degS (hhoB) is an essential Escherichia coli gene whose indispensable function is to provide sigma (E) activity.
Molecular microbiology 2001;40(6):1323-33.
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2001: Young B A; Anthony L C; Gruber T M; Arthur T M; Heyduk E; Lu C Z; Sharp M M; Heyduk T; Burgess R R; Gross C A
A coiled-coil from the RNA polymerase beta' subunit allosterically induces selective nontemplate strand binding by sigma(70).
Cell 2001;105(7):935-44.
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2001: Cicero M P; Sharp M M; Gross C A; Kreuzer K N
Substitutions in bacteriophage T4 AsiA and Escherichia coli sigma(70) that suppress T4 motA activation mutations.
Journal of bacteriology 2001;183(7):2289-97.
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2001: Behrens S; Maier R; de Cock H; Schmid F X; Gross C A
The SurA periplasmic PPIase lacking its parvulin domains functions in vivo and has chaperone activity.
The EMBO journal 2001;20(1-2):285-94.
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1999: Sharp M M; Chan C L; Lu C Z; Marr M T; Nechaev S; Merritt E W; Severinov K; Roberts J W; Gross C A
The interface of sigma with core RNA polymerase is extensive, conserved, and functionally specialized.
Genes & development 1999;13(22):3015-26.
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1999: Suh W C; Lu C Z; Gross C A
Structural features required for the interaction of the Hsp70 molecular chaperone DnaK with its cochaperone DnaJ.
The Journal of biological chemistry 1999;274(43):30534-9.
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1999: Ades S E; Connolly L E; Alba B M; Gross C A
The Escherichia coli sigma(E)-dependent extracytoplasmic stress response is controlled by the regulated proteolysis of an anti-sigma factor.
Genes & development 1999;13(18):2449-61.
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1998: Suh W C; Burkholder W F; Lu C Z; Zhao X; Gottesman M E; Gross C A
Interaction of the Hsp70 molecular chaperone, DnaK, with its cochaperone DnaJ.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(26):15223-8.
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1998: Gross C A; Chan C; Dombroski A; Gruber T; Sharp M; Tupy J; Young B
The functional and regulatory roles of sigma factors in transcription.
Cold Spring Harbor symposia on quantitative biology 1998;63():141-55.
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1997: De Las Peñas A; Connolly L; Gross C A
SigmaE is an essential sigma factor in Escherichia coli.
Journal of bacteriology 1997;179(21):6862-4.
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1997: Connolly L; De Las Penas A; Alba B M; Gross C A
The response to extracytoplasmic stress in Escherichia coli is controlled by partially overlapping pathways.
Genes & development 1997;11(15):2012-21.
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1997: De Las Peñas A; Connolly L; Gross C A
The sigmaE-mediated response to extracytoplasmic stress in Escherichia coli is transduced by RseA and RseB, two negative regulators of sigmaE.
Molecular microbiology 1997;24(2):373-85.
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1996: Rouvière P E; Gross C A
SurA, a periplasmic protein with peptidyl-prolyl isomerase activity, participates in the assembly of outer membrane porins.
Genes & development 1996;10(24):3170-82.
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1996: Chan C L; Lonetto M A; Gross C A
Sigma domain structure: one down, one to go.
Structure (London, England : 1993) 1996;4(11):1235-8.
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1996: Tavormina P L; Landick R; Gross C A
Isolation, purification, and in vitro characterization of recessive-lethal-mutant RNA polymerases from Escherichia coli.
Journal of bacteriology 1996;178(17):5263-71.
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1996: Dombroski A J; Johnson B D; Lonetto M; Gross C A
The sigma subunit of Escherichia coli RNA polymerase senses promoter spacing.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(17):8858-62.
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1996: Heisler L M; Feng G; Jin D J; Gross C A; Landick R
Amino acid substitutions in the two largest subunits of Escherichia coli RNA polymerase that suppress a defective Rho termination factor affect different parts of the transcription complex.
The Journal of biological chemistry 1996;271(24):14572-83.
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1996: Wild J; Rossmeissl P; Walter W A; Gross C A
Involvement of the DnaK-DnaJ-GrpE chaperone team in protein secretion in Escherichia coli.
Journal of bacteriology 1996;178(12):3608-13.
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1996: Tavormina P L; Reznikoff W S; Gross C A
Identifying interacting regions in the beta subunit of Escherichia coli RNA polymerase.
Journal of molecular biology 1996;258(2):213-23.
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1996: Gross C A; Chan C L; Lonetto M A
A structure/function analysis of Escherichia coli RNA polymerase.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 1996;351(1339):475-82.
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1995: Kamath-Loeb A S; Lu C Z; Suh W C; Lonetto M A; Gross C A
Analysis of three DnaK mutant proteins suggests that progression through the ATPase cycle requires conformational changes.
The Journal of biological chemistry 1995;270(50):30051-9.
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1995: Rouvière P E; De Las Peñas A; Mecsas J; Lu C Z; Rudd K E; Gross C A
rpoE, the gene encoding the second heat-shock sigma factor, sigma E, in Escherichia coli.
The EMBO journal 1995;14(5):1032-42.
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1995: Mecsas J; Welch R; Erickson J W; Gross C A
Identification and characterization of an outer membrane protein, OmpX, in Escherichia coli that is homologous to a family of outer membrane proteins including Ail of Yersinia enterocolitica.
Journal of bacteriology 1995;177(3):799-804.
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1993: Mecsas J; Rouviere P E; Erickson J W; Donohue T J; Gross C A
The activity of sigma E, an Escherichia coli heat-inducible sigma-factor, is modulated by expression of outer membrane proteins.
Genes & development 1993;7(12B):2618-28.
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1993: Dombroski A J; Walter W A; Gross C A
Amino-terminal amino acids modulate sigma-factor DNA-binding activity.
Genes & development 1993;7(12A):2446-55.
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1993: Heisler L M; Suzuki H; Landick R; Gross C A
Four contiguous amino acids define the target for streptolydigin resistance in the beta subunit of Escherichia coli RNA polymerase.
The Journal of biological chemistry 1993;268(34):25369-75.
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1993: Wild J; Walter W A; Gross C A; Altman E
Accumulation of secretory protein precursors in Escherichia coli induces the heat shock response.
Journal of bacteriology 1993;175(13):3992-7.
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1993: Singer M; Jin D J; Walter W A; Gross C A
Genetic evidence for the interaction between cluster I and cluster III rifampicin resistant mutations.
Journal of molecular biology 1993;231(1):1-5.
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1993: Dombroski A J; Walter W A; Gross C A
The role of the sigma subunit in promoter recognition by RNA polymerase.
Cellular & molecular biology research 1993;39(4):311-7.
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1992: Zhou Y N; Gross C A
How a mutation in the gene encoding sigma 70 suppresses the defective heat shock response caused by a mutation in the gene encoding sigma 32.
Journal of bacteriology 1992;174(22):7128-37.
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1992: Dombroski A J; Walter W A; Record M T; Siegele D A; Gross C A
Polypeptides containing highly conserved regions of transcription initiation factor sigma 70 exhibit specificity of binding to promoter DNA.
Cell 1992;70(3):501-12.
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1992: Zhou Y N; Walter W A; Gross C A
A mutant sigma 32 with a small deletion in conserved region 3 of sigma has reduced affinity for core RNA polymerase.
Journal of bacteriology 1992;174(15):5005-12.
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1992: Wild J; Kamath-Loeb A; Ziegelhoffer E; Lonetto M; Kawasaki Y; Gross C A
Partial loss of function mutations in DnaK, the Escherichia coli homologue of the 70-kDa heat shock proteins, affect highly conserved amino acids implicated in ATP binding and hydrolysis.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(15):7139-43.
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1992: Wild J; Altman E; Yura T; Gross C A
DnaK and DnaJ heat shock proteins participate in protein export in Escherichia coli.
Genes & development 1992;6(7):1165-72.
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1992: Lonetto M; Gribskov M; Gross C A
The sigma 70 family: sequence conservation and evolutionary relationships.
Journal of bacteriology 1992;174(12):3843-9.
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1992: Jin D J; Burgess R R; Richardson J P; Gross C A
Termination efficiency at rho-dependent terminators depends on kinetic coupling between RNA polymerase and rho.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(4):1453-7.
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1991: Singer M; Rossmiessl P; Cali B M; Liebke H; Gross C A
The Escherichia coli ts8 mutation is an allele of fda, the gene encoding fructose-1,6-diphosphate aldolase.
Journal of bacteriology 1991;173(19):6242-8.
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1991: Singer M; Walter W A; Cali B M; Rouviere P; Liebke H H; Gourse R L; Gross C A
Physiological effects of the fructose-1,6-diphosphate aldolase ts8 mutation on stable RNA synthesis in Escherichia coli.
Journal of bacteriology 1991;173(19):6249-57.
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1991: Jin D J; Gross C A
RpoB8, a rifampicin-resistant termination-proficient RNA polymerase, has an increased Km for purine nucleotides during transcription elongation.
The Journal of biological chemistry 1991;266(22):14478-85.
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1991: Mecsas J; Cowing D W; Gross C A
Development of RNA polymerase-promoter contacts during open complex formation.
Journal of molecular biology 1991;220(3):585-97.
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1991: Kamath-Loeb A S; Gross C A
Translational regulation of sigma 32 synthesis: requirement for an internal control element.
Journal of bacteriology 1991;173(12):3904-6.
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1990: Straus D; Walter W; Gross C A
DnaK, DnaJ, and GrpE heat shock proteins negatively regulate heat shock gene expression by controlling the synthesis and stability of sigma 32.
Genes & development 1990;4(12A):2202-9.
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1989: Straus D B; Walter W A; Gross C A
The activity of sigma 32 is reduced under conditions of excess heat shock protein production in Escherichia coli.
Genes & development 1989;3(12A):2003-10.
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1989: Cowing D W; Mecsas J; Record M T; Gross C A
Intermediates in the formation of the open complex by RNA polymerase holoenzyme containing the sigma factor sigma 32 at the groE promoter.
Journal of molecular biology 1989;210(3):521-30.
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1989: Cowing D W; Gross C A
Interaction of Escherichia coli RNA polymerase holoenzyme containing sigma 32 with heat shock promoters. DNase I footprinting and methylation protection.
Journal of molecular biology 1989;210(3):513-20.
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1989: Erickson J W; Gross C A
Identification of the sigma E subunit of Escherichia coli RNA polymerase: a second alternate sigma factor involved in high-temperature gene expression.
Genes & development 1989;3(9):1462-71.
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1989: Jin D J; Gross C A
Characterization of the pleiotropic phenotypes of rifampin-resistant rpoB mutants of Escherichia coli.
Journal of bacteriology 1989;171(9):5229-31.
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1989: Jin D J; Gross C A
Three rpoBC mutations that suppress the termination defects of rho mutants also affect the functions of nusA mutants.
Molecular & general genetics : MGG 1989;216(2-3):269-75.
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1989: Siegele D A; Hu J C; Walter W A; Gross C A
Altered promoter recognition by mutant forms of the sigma 70 subunit of Escherichia coli RNA polymerase.
Journal of molecular biology 1989;206(4):591-603.
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1988: Straus D B; Walter W A; Gross C A
Escherichia coli heat shock gene mutants are defective in proteolysis.
Genes & development 1988;2(12B):1851-8.
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1988: Jin D J; Cashel M; Friedman D I; Nakamura Y; Walter W A; Gross C A
Effects of rifampicin resistant rpoB mutations on antitermination and interaction with nusA in Escherichia coli.
Journal of molecular biology 1988;204(2):247-61.
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1988: Hu J C; Gross C A
Mutations in rpoD that increase expression of genes in the mal regulon of Escherichia coli K-12.
Journal of molecular biology 1988;203(1):15-27.
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1988: Siegele D A; Hu J C; Gross C A
Mutations in rpoD, the gene encoding the sigma 70 subunit of Escherichia coli RNA polymerase, that increase expression of the lac operon in the absence of CAP-cAMP.
Journal of molecular biology 1988;203(1):29-37.
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1988: Zhou Y N; Kusukawa N; Erickson J W; Gross C A; Yura T
Isolation and characterization of Escherichia coli mutants that lack the heat shock sigma factor sigma 32.
Journal of bacteriology 1988;170(8):3640-9.
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1988: Jin D J; Walter W A; Gross C A
Characterization of the termination phenotypes of rifampicin-resistant mutants.
Journal of molecular biology 1988;202(2):245-53.
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1988: Jin D J; Gross C A
Mapping and sequencing of mutations in the Escherichia coli rpoB gene that lead to rifampicin resistance.
Journal of molecular biology 1988;202(1):45-58.
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1987: Straus D B; Walter W A; Gross C A
The heat shock response of E. coli is regulated by changes in the concentration of sigma 32.
Nature 1987;329(6137):348-51.
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1987: Erickson J W; Vaughn V; Walter W A; Neidhardt F C; Gross C A
Regulation of the promoters and transcripts of rpoH, the Escherichia coli heat shock regulatory gene.
Genes & development 1987;1(5):419-32.
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1987: Grossman A D; Straus D B; Walter W A; Gross C A
Sigma 32 synthesis can regulate the synthesis of heat shock proteins in Escherichia coli.
Genes & development 1987;1(2):179-84.
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1985: Grossman A D; Taylor W E; Burton Z F; Burgess R R; Gross C A
Stringent response in Escherichia coli induces expression of heat shock proteins.
Journal of molecular biology 1985;186(2):357-65.
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1985: Cowing D W; Bardwell J C; Craig E A; Woolford C; Hendrix R W; Gross C A
Consensus sequence for Escherichia coli heat shock gene promoters.
Proceedings of the National Academy of Sciences of the United States of America 1985;82(9):2679-83.
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1985: Reznikoff W S; Siegele D A; Cowing D W; Gross C A
The regulation of transcription initiation in bacteria.
Annual review of genetics 1985;19():355-87.
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1985: Hu J C; Gross C A
Mutations in the sigma subunit of E. coli RNA polymerase which affect positive control of transcription.
Molecular & general genetics : MGG 1985;199(1):7-13.
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1984: Taylor W E; Straus D B; Grossman A D; Burton Z F; Gross C A; Burgess R R
Transcription from a heat-inducible promoter causes heat shock regulation of the sigma subunit of E. coli RNA polymerase.
Cell 1984;38(2):371-81.
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1984: Gross C A; Grossman A D; Liebke H; Walter W; Burgess R R
Effects of the mutant sigma allele rpoD800 on the synthesis of specific macromolecular components of the Escherichia coli K12 cell.
Journal of molecular biology 1984;172(3):283-300.
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1983: Burton Z F; Gross C A; Watanabe K K; Burgess R R
The operon that encodes the sigma subunit of RNA polymerase also encodes ribosomal protein S21 and DNA primase in E. coli K12.
Cell 1983;32(2):335-49.
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1983: Grossman A D; Burgess R R; Walter W; Gross C A
Mutations in the Ion gene of E. coli K12 phenotypically suppress a mutation in the sigma subunit of RNA polymerase.
Cell 1983;32(1):151-9.
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1983: Hu J C; Gross C A
Marker rescue with plasmids bearing deletions in rpoD identifies a dispensable part of E. coli sigma factor.
Molecular & general genetics : MGG 1983;191(3):492-8.
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