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Alan Grossman

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

Research Profile (preview)

Living Beings

Bacillus subtilis

Chemicals & Drugs

Anatomy

Physiology

Genes & Molecular Sequences

Bacterial Genes

Concepts & Ideas

Molecular Sequence Data

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Co-Publications
Name
7
Lazazzera, Beth
7
Lin, Daniel Chi-Hong
6
Lee, Catherine
6
Auchtung, Jennifer
6
Walker, Graham
6
Kurtser, Iren
5
Lemon, KP
5
Britton, Robert
5
Goranov, Alexi
4
Simmons, Lyle
4
Wang, Jue
4
Levin, PA
3
Quisel, JD
3
Rokop, Megan
3
Losick, Richard

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Publications

TOP 3
Goranov Alexi I; Breier Adam M; Merrikh Houra; Grossman Alan D
YabA of Bacillus subtilis controls DnaA-mediated replication initiation but not the transcriptional response to replication stress.
Simmons Lyle A; Goranov Alexi I; Kobayashi Hajime; Davies Bryan W; Yuan Daniel S; Grossman Alan D; Walker Graham C
Comparison of responses to double-strand breaks between Escherichia coli and Bacillus subtilis reveals different requirements for SOS induction.
Breier Adam M; Grossman Alan D
Dynamic association of the replication initiator and transcription factor DnaA with the Bacillus subtilis chromosome during replication stress.

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All Publications

2009: Goranov Alexi I; Breier Adam M; Merrikh Houra; Grossman Alan D
YabA of Bacillus subtilis controls DnaA-mediated replication initiation but not the transcriptional response to replication stress.
Molecular microbiology 2009;74(2):454-66.
2009: Simmons Lyle A; Goranov Alexi I; Kobayashi Hajime; Davies Bryan W; Yuan Daniel S; Grossman Alan D; Walker Graham C
Comparison of responses to double-strand breaks between Escherichia coli and Bacillus subtilis reveals different requirements for SOS induction.
Journal of bacteriology 2009;191(4):1152-61.
2009: Breier Adam M; Grossman Alan D
Dynamic association of the replication initiator and transcription factor DnaA with the Bacillus subtilis chromosome during replication stress.
Journal of bacteriology 2009;191(2):486-93.
2009: Rokop Megan E; Grossman Alan D
Intragenic and extragenic suppressors of temperature sensitive mutations in the replication initiation genes dnaD and dnaB of Bacillus subtilis.
PloS one 2009;4(8):e6774.
2008: Griffith Kevin L; Grossman Alan D
Inducible protein degradation in Bacillus subtilis using heterologous peptide tags and adaptor proteins to target substrates to the protease ClpXP.
Molecular microbiology 2008;70(4):1012-25.
2008: Bose Baundauna; Auchtung Jennifer M; Lee Catherine A; Grossman Alan D
A conserved anti-repressor controls horizontal gene transfer by proteolysis.
Molecular microbiology 2008;70(3):570-82.
2008: Simmons Lyle A; Grossman Alan D; Walker Graham C
Clp and Lon proteases occupy distinct subcellular positions in Bacillus subtilis.
Journal of bacteriology 2008;190(20):6758-68.
2008: Griffith Kevin L; Grossman Alan D
A degenerate tripartite DNA-binding site required for activation of ComA-dependent quorum response gene expression in Bacillus subtilis.
Journal of molecular biology 2008;381(2):261-75.
2008: Simmons Lyle A; Davies Bryan W; Grossman Alan D; Walker Graham C
Beta clamp directs localization of mismatch repair in Bacillus subtilis.
Molecular cell 2008;29(3):291-301.
2007: Lee Catherine A; Auchtung Jennifer M; Monson Rita E; Grossman Alan D
Identification and characterization of int (integrase), xis (excisionase) and chromosomal attachment sites of the integrative and conjugative element ICEBs1 of Bacillus subtilis.
Molecular microbiology 2007;66(6):1356-69.
2007: Lee Catherine A; Grossman Alan D
Identification of the origin of transfer (oriT) and DNA relaxase required for conjugation of the integrative and conjugative element ICEBs1 of Bacillus subtilis.
Journal of bacteriology 2007;189(20):7254-61.
2007: Auchtung Jennifer M; Lee Catherine A; Garrison Katherine L; Grossman Alan D
Identification and characterization of the immunity repressor (ImmR) that controls the mobile genetic element ICEBs1 of Bacillus subtilis.
Molecular microbiology 2007;64(6):1515-28.
2007: Britton Robert A; Küster-Schöck Elke; Auchtung Thomas A; Grossman Alan D
SOS induction in a subpopulation of structural maintenance of chromosome (Smc) mutant cells in Bacillus subtilis.
Journal of bacteriology 2007;189(12):4359-66.
2007: Breier Adam M; Grossman Alan D
Whole-genome analysis of the chromosome partitioning and sporulation protein Spo0J (ParB) reveals spreading and origin-distal sites on the Bacillus subtilis chromosome.
Molecular microbiology 2007;64(3):703-18.
2007: Wang Jue D; Berkmen Melanie B; Grossman Alan D
Genome-wide coorientation of replication and transcription reduces adverse effects on replication in Bacillus subtilis.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(13):5608-13.
2007: Wang Jue D; Sanders Glenn M; Grossman Alan D
Nutritional control of elongation of DNA replication by (p)ppGpp.
Cell 2007;128(5):865-75.
2007: Simmons Lyle A; Grossman Alan D; Walker Graham C
Replication is required for the RecA localization response to DNA damage in Bacillus subtilis.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(4):1360-5.
2007: Berkmen Melanie B; Grossman Alan D
Subcellular positioning of the origin region of the Bacillus subtilis chromosome is independent of sequences within oriC, the site of replication initiation, and the replication initiator DnaA.
Molecular microbiology 2007;63(1):150-65.
2006: Berkmen Melanie B; Grossman Alan D
Spatial and temporal organization of the Bacillus subtilis replication cycle.
Molecular microbiology 2006;62(1):57-71.
2006: Goranov Alexi I; Kuester-Schoeck Elke; Wang Jue D; Grossman Alan D
Characterization of the global transcriptional responses to different types of DNA damage and disruption of replication in Bacillus subtilis.
Journal of bacteriology 2006;188(15):5595-605.
2006: Auchtung Jennifer M; Lee Catherine A; Grossman Alan D
Modulation of the ComA-dependent quorum response in Bacillus subtilis by multiple Rap proteins and Phr peptides.
Journal of bacteriology 2006;188(14):5273-85.
2006: Lee Philina S; Grossman Alan D
The chromosome partitioning proteins Soj (ParA) and Spo0J (ParB) contribute to accurate chromosome partitioning, separation of replicated sister origins, and regulation of replication initiation in Bacillus subtilis.
Molecular microbiology 2006;60(4):853-69.
2005: Au Nora; Kuester-Schoeck Elke; Mandava Veena; Bothwell Laura E; Canny Susan P; Chachu Karen; Colavito Sierra A; Fuller Shakierah N; Groban Eli S; Hensley Laura A; O'Brien Theresa C; Shah Amish; Tierney Jessica T; Tomm Louise L; O'Gara Thomas M; Goranov Alexi I; Grossman Alan D; Lovett Charles M
Genetic composition of the Bacillus subtilis SOS system.
Journal of bacteriology 2005;187(22):7655-66.
2005: Farrell Christopher M; Grossman Alan D; Sauer Robert T
Cytoplasmic degradation of ssrA-tagged proteins.
Molecular microbiology 2005;57(6):1750-61.
2005: Goranov Alexi I; Katz Luba; Breier Adam M; Burge Christopher B; Grossman Alan D
A transcriptional response to replication status mediated by the conserved bacterial replication protein DnaA.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(36):12932-7.
2005: Auchtung Jennifer M; Lee Catherine A; Monson Rita E; Lehman Alisa P; Grossman Alan D
Regulation of a Bacillus subtilis mobile genetic element by intercellular signaling and the global DNA damage response.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(35):12554-9.
2005: Comella Natalia; Grossman Alan D
Conservation of genes and processes controlled by the quorum response in bacteria: characterization of genes controlled by the quorum-sensing transcription factor ComA in Bacillus subtilis.
Molecular microbiology 2005;57(4):1159-74.
2004: Wang Jue D; Rokop Megan E; Barker Melanie M; Hanson Nathaniel R; Grossman Alan D
Multicopy plasmids affect replisome positioning in Bacillus subtilis.
Journal of bacteriology 2004;186(21):7084-90.
2004: Rokop Megan E; Auchtung Jennifer M; Grossman Alan D
Control of DNA replication initiation by recruitment of an essential initiation protein to the membrane of Bacillus subtilis.
Molecular microbiology 2004;52(6):1757-67.
2004: Hamon Mélanie A; Stanley Nicola R; Britton Robert A; Grossman Alan D; Lazazzera Beth A
Identification of AbrB-regulated genes involved in biofilm formation by Bacillus subtilis.
Molecular microbiology 2004;52(3):847-60.
2004: Rowland Susan L; Burkholder William F; Cunningham Katherine A; Maciejewski Mark W; Grossman Alan D; King Glenn F
Structure and mechanism of action of Sda, an inhibitor of the histidine kinases that regulate initiation of sporulation in Bacillus subtilis.
Molecular cell 2004;13(5):689-701.
2003: Nakano Shunji; Küster-Schöck Elke; Grossman Alan D; Zuber Peter
Spx-dependent global transcriptional control is induced by thiol-specific oxidative stress in Bacillus subtilis.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(23):13603-8.
2003: Solomon Jonathan; Su Laura; Shyn Stanley; Grossman Alan D
Isolation and characterization of mutants of the Bacillus subtilis oligopeptide permease with altered specificity of oligopeptide transport.
Journal of bacteriology 2003;185(21):6425-33.
2003: Stanley Nicola R; Britton Robert A; Grossman Alan D; Lazazzera Beth A
Identification of catabolite repression as a physiological regulator of biofilm formation by Bacillus subtilis by use of DNA microarrays.
Journal of bacteriology 2003;185(6):1951-7.
2003: Lee Philina S; Lin Daniel Chi-Hong; Moriya Shigeki; Grossman Alan D
Effects of the chromosome partitioning protein Spo0J (ParB) on oriC positioning and replication initiation in Bacillus subtilis.
Journal of bacteriology 2003;185(4):1326-37.
2002: Lindow Janet C; Kuwano Masayoshi; Moriya Shigeki; Grossman Alan D
Subcellular localization of the Bacillus subtilis structural maintenance of chromosomes (SMC) protein.
Molecular microbiology 2002;46(4):997-1009.
2002: Lindow Janet C; Britton Robert A; Grossman Alan D
Structural maintenance of chromosomes protein of Bacillus subtilis affects supercoiling in vivo.
Journal of bacteriology 2002;184(19):5317-22.
2002: Britton Robert A; Eichenberger Patrick; Gonzalez-Pastor Jose Eduardo; Fawcett Paul; Monson Rita; Losick Richard; Grossman Alan D
Genome-wide analysis of the stationary-phase sigma factor (sigma-H) regulon of Bacillus subtilis.
Journal of bacteriology 2002;184(17):4881-90.
2002: Ozbudak Ertugrul M; Thattai Mukund; Kurtser Iren; Grossman Alan D; van Oudenaarden Alexander
Regulation of noise in the expression of a single gene.
Nature genetics 2002;31(1):69-73.
2002: Smith Bradley T; Grossman Alan D; Walker Graham C
Localization of UvrA and effect of DNA damage on the chromosome of Bacillus subtilis.
Journal of bacteriology 2002;184(2):488-93.
2002: Bacon Schneider Katherine; Palmer Tanya M; Grossman Alan D
Characterization of comQ and comX, two genes required for production of ComX pheromone in Bacillus subtilis.
Journal of bacteriology 2002;184(2):410-9.
2001: Smith B T; Grossman A D; Walker G C
Visualization of mismatch repair in bacterial cells.
Molecular cell 2001;8(6):1197-206.
2001: Quisel J D; Burkholder W F; Grossman A D
In vivo effects of sporulation kinases on mutant Spo0A proteins in Bacillus subtilis.
Journal of bacteriology 2001;183(22):6573-8.
2001: Levin P A; Schwartz R L; Grossman A D
Polymer stability plays an important role in the positional regulation of FtsZ.
Journal of bacteriology 2001;183(18):5449-52.
2001: Lemon K P; Grossman A D
The extrusion-capture model for chromosome partitioning in bacteria.
Genes & development 2001;15(16):2031-41.
2001: McQuade R S; Comella N; Grossman A D
Control of a family of phosphatase regulatory genes (phr) by the alternate sigma factor sigma-H of Bacillus subtilis.
Journal of bacteriology 2001;183(16):4905-9.
2001: Burkholder W F; Kurtser I; Grossman A D
Replication initiation proteins regulate a developmental checkpoint in Bacillus subtilis.
Cell 2001;104(2):269-79.
2001: Lemon K P; Kurtser I; Grossman A D
Effects of replication termination mutants on chromosome partitioning in Bacillus subtilis.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(1):212-7.
2000: Lemon K P; Grossman A D
Movement of replicating DNA through a stationary replisome.
Molecular cell 2000;6(6):1321-30.
2000: Quisel J D; Grossman A D
Control of sporulation gene expression in Bacillus subtilis by the chromosome partitioning proteins Soj (ParA) and Spo0J (ParB).
Journal of bacteriology 2000;182(12):3446-51.
2000: Lemon K P; Kurtser I; Wu J; Grossman A D
Control of initiation of sporulation by replication initiation genes in Bacillus subtilis.
Journal of bacteriology 2000;182(10):2989-91.
1999: Quisel J D; Lin D C; Grossman A D
Control of development by altered localization of a transcription factor in B. subtilis.
Molecular cell 1999;4(5):665-72.
1999: Britton R A; Grossman A D
Synthetic lethal phenotypes caused by mutations affecting chromosome partitioning in Bacillus subtilis.
Journal of bacteriology 1999;181(18):5860-4.
1999: Lazazzera B A; Kurtser I G; McQuade R S; Grossman A D
An autoregulatory circuit affecting peptide signaling in Bacillus subtilis.
Journal of bacteriology 1999;181(17):5193-200.
1999: Levin P A; Kurtser I G; Grossman A D
Identification and characterization of a negative regulator of FtsZ ring formation in Bacillus subtilis.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(17):9642-7.
1998: Levin P A; Grossman A D
Cell cycle and sporulation in Bacillus subtilis.
Current opinion in microbiology 1998;1(6):630-5.
1998: Lemon K P; Grossman A D
Localization of bacterial DNA polymerase: evidence for a factory model of replication.
Science (New York, N.Y.) 1998;282(5393):1516-9.
1998: Levin P A; Shim J J; Grossman A D
Effect of minCD on FtsZ ring position and polar septation in Bacillus subtilis.
Journal of bacteriology 1998;180(22):6048-51.
1998: Teleman A A; Graumann P L; Lin D C; Grossman A D; Losick R
Chromosome arrangement within a bacterium.
Current biology : CB 1998;8(20):1102-9.
1998: Lazazzera B A; Grossman A D
The ins and outs of peptide signaling.
Trends in microbiology 1998;6(7):288-94.
1998: Britton R A; Lin D C; Grossman A D
Characterization of a prokaryotic SMC protein involved in chromosome partitioning.
Genes & development 1998;12(9):1254-9.
1998: Lin D C; Grossman A D
Identification and characterization of a bacterial chromosome partitioning site.
Cell 1998;92(5):675-85.
1998: Levin P A; Grossman A D
Cell cycle: the bacterial approach to coordination.
Current biology : CB 1998;8(1):R28-31.
1997: LeDeaux J R; Solomon J M; Grossman A D
Analysis of non-polar deletion mutations in the genes of the spo0K (opp) operon of Bacillus subtilis.
FEMS microbiology letters 1997;153(1):63-9.
1997: Jin S; Levin P A; Matsuno K; Grossman A D; Sonenshein A L
Deletion of the Bacillus subtilis isocitrate dehydrogenase gene causes a block at stage I of sporulation.
Journal of bacteriology 1997;179(15):4725-32.
1997: Lazazzera B A; Grossman A D
A regulatory switch involving a Clp ATPase.
BioEssays : news and reviews in molecular, cellular and developmental biology 1997;19(6):455-8.
1997: Lazazzera B A; Solomon J M; Grossman A D
An exported peptide functions intracellularly to contribute to cell density signaling in B. subtilis.
Cell 1997;89(6):917-25.
1997: Lin D C; Levin P A; Grossman A D
Bipolar localization of a chromosome partition protein in Bacillus subtilis.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(9):4721-6.
1997: Webb C D; Teleman A; Gordon S; Straight A; Belmont A; Lin D C; Grossman A D; Wright A; Losick R
Bipolar localization of the replication origin regions of chromosomes in vegetative and sporulating cells of B. subtilis.
Cell 1997;88(5):667-74.
1996: Solomon J M; Lazazzera B A; Grossman A D
Purification and characterization of an extracellular peptide factor that affects two different developmental pathways in Bacillus subtilis.
Genes & development 1996;10(16):2014-24.
1996: Solomon J M; Grossman A D
Who's competent and when: regulation of natural genetic competence in bacteria.
Trends in genetics : TIG 1996;12(4):150-5.
1996: Hicks K A; Grossman A D
Altering the level and regulation of the major sigma subunit of RNA polymerase affects gene expression and development in Bacillus subtilis.
Molecular microbiology 1996;20(1):201-12.
1995: Hicks K A; Grossman A D
Characterization of csh203::Tn917lac, a mutation in Bacillus subtilis that makes the sporulation sigma factor sigma-H essential for normal vegetative growth.
Journal of bacteriology 1995;177(13):3736-42.
1995: Vidwans S J; Ireton K; Grossman A D
Possible role for the essential GTP-binding protein Obg in regulating the initiation of sporulation in Bacillus subtilis.
Journal of bacteriology 1995;177(11):3308-11.
1995: Ireton K; Jin S; Grossman A D; Sonenshein A L
Krebs cycle function is required for activation of the Spo0A transcription factor in Bacillus subtilis.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(7):2845-9.
1995: Solomon J M; Magnuson R; Srivastava A; Grossman A D
Convergent sensing pathways mediate response to two extracellular competence factors in Bacillus subtilis.
Genes & development 1995;9(5):547-58.
1995: LeDeaux J R; Yu N; Grossman A D
Different roles for KinA, KinB, and KinC in the initiation of sporulation in Bacillus subtilis.
Journal of bacteriology 1995;177(3):861-3.
1995: LeDeaux J R; Grossman A D
Isolation and characterization of kinC, a gene that encodes a sensor kinase homologous to the sporulation sensor kinases KinA and KinB in Bacillus subtilis.
Journal of bacteriology 1995;177(1):166-75.
1995: Grossman A D
Genetic networks controlling the initiation of sporulation and the development of genetic competence in Bacillus subtilis.
Annual review of genetics 1995;29():477-508.
1994: Ireton K; Gunther N W; Grossman A D
spo0J is required for normal chromosome segregation as well as the initiation of sporulation in Bacillus subtilis.
Journal of bacteriology 1994;176(17):5320-9.
1994: Siranosian K J; Grossman A D
Activation of spo0A transcription by sigma H is necessary for sporulation but not for competence in Bacillus subtilis.
Journal of bacteriology 1994;176(12):3812-5.
1994: Magnuson R; Solomon J; Grossman A D
Biochemical and genetic characterization of a competence pheromone from B. subtilis.
Cell 1994;77(2):207-16.
1994: Ireton K; Grossman A D
A developmental checkpoint couples the initiation of sporulation to DNA replication in Bacillus subtilis.
The EMBO journal 1994;13(7):1566-73.
1994: Chung J D; Stephanopoulos G; Ireton K; Grossman A D
Gene expression in single cells of Bacillus subtilis: evidence that a threshold mechanism controls the initiation of sporulation.
Journal of bacteriology 1994;176(7):1977-84.
1994: Ireton K; Grossman A D
DNA-related conditions controlling the initiation of sporulation in Bacillus subtilis.
Cellular & molecular biology research 1994;40(3):193-8.
1993: Siranosian K J; Ireton K; Grossman A D
Alanine dehydrogenase (ald) is required for normal sporulation in Bacillus subtilis.
Journal of bacteriology 1993;175(21):6789-96.
1993: Kong L; Siranosian K J; Grossman A D; Dubnau D
Sequence and properties of mecA, a negative regulator of genetic competence in Bacillus subtilis.
Molecular microbiology 1993;9(2):365-73.
1993: Ireton K; Rudner D Z; Siranosian K J; Grossman A D
Integration of multiple developmental signals in Bacillus subtilis through the Spo0A transcription factor.
Genes & development 1993;7(2):283-94.
1992: Ireton K; Grossman A D
Coupling between gene expression and DNA synthesis early during development in Bacillus subtilis.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(18):8808-12.
1992: Grossman A D; Lewis T; Levin N; DeVivo R
Suppressors of a spo0A missense mutation and their effects on sporulation in Bacillus subtilis.
Biochimie 1992;74(7-8):679-88.
1992: Ireton K; Grossman A D
Interactions among mutations that cause altered timing of gene expression during sporulation in Bacillus subtilis.
Journal of bacteriology 1992;174(10):3185-95.
1991: Grossman A D
Integration of developmental signals and the initiation of sporulation in B. subtilis.
Cell 1991;65(1):5-8.
1991: Nakano M M; Magnuson R; Myers A; Curry J; Grossman A D; Zuber P
srfA is an operon required for surfactin production, competence development, and efficient sporulation in Bacillus subtilis.
Journal of bacteriology 1991;173(5):1770-8.
1991: Rudner D Z; LeDeaux J R; Ireton K; Grossman A D
The spo0K locus of Bacillus subtilis is homologous to the oligopeptide permease locus and is required for sporulation and competence.
Journal of bacteriology 1991;173(4):1388-98.

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