James Grotta

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Martin-Schild Sheryl; Albright Karen C; Misra Vivek; Philip Maria; Barreto Andrew D; Hallevi Hen; Grotta James C; Savitz Sean I
Intravenous tissue plasminogen activator in patients with cocaine-associated acute ischemic stroke.
Molina Carlos A; Barreto Andrew D; Tsivgoulis Georgios; Sierzenski Paul; Malkoff Marc D; Rubiera Marta; Gonzales Nicole; Mikulik Robert; Pate Greg; Ostrem James; Singleton Walter; Manvelian Garen; Unger Evan C; Grotta James C; Schellinger Peter D; Alexandrov Andrei V
Transcranial ultrasound in clinical sonothrombolysis (TUCSON) trial.
Zhao Xiurong; Strong Roger; Zhang Jie; Sun Guanghua; Tsien Joe Z; Cui Zhenzhong; Grotta James C; Aronowski Jaroslaw
Neuronal PPARgamma deficiency increases susceptibility to brain damage after cerebral ischemia.

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2009: Martin-Schild Sheryl; Albright Karen C; Misra Vivek; Philip Maria; Barreto Andrew D; Hallevi Hen; Grotta James C; Savitz Sean I
Intravenous tissue plasminogen activator in patients with cocaine-associated acute ischemic stroke.
Stroke; a journal of cerebral circulation 2009;40(11):3635-7.
2009: Molina Carlos A; Barreto Andrew D; Tsivgoulis Georgios; Sierzenski Paul; Malkoff Marc D; Rubiera Marta; Gonzales Nicole; Mikulik Robert; Pate Greg; Ostrem James; Singleton Walter; Manvelian Garen; Unger Evan C; Grotta James C; Schellinger Peter D; Alexandrov Andrei V
Transcranial ultrasound in clinical sonothrombolysis (TUCSON) trial.
Annals of neurology 2009;66(1):28-38.
2009: Zhao Xiurong; Strong Roger; Zhang Jie; Sun Guanghua; Tsien Joe Z; Cui Zhenzhong; Grotta James C; Aronowski Jaroslaw
Neuronal PPARgamma deficiency increases susceptibility to brain damage after cerebral ischemia.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2009;29(19):6186-95.
2009: Hallevi Hen; Barreto Andrew D; Liebeskind David S; Morales Miriam M; Martin-Schild Sheryl B; Abraham Anitha T; Gadia Jignesh; Saver Jeffrey L; Grotta James C; Savitz Sean I
Identifying patients at high risk for poor outcome after intra-arterial therapy for acute ischemic stroke.
Stroke; a journal of cerebral circulation 2009;40(5):1780-5.
2009: Martin-Schild Sheryl; Hallevi Hen; Shaltoni Hashem; Barreto Andrew D; Gonzales Nicole R; Aronowski Jarek; Savitz Sean I; Grotta James C
Combined neuroprotective modalities coupled with thrombolysis in acute ischemic stroke: a pilot study of caffeinol and mild hypothermia.
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2009;18(2):86-96.
2009: Hallevi Hen; Dar Nabeel S; Barreto Andrew D; Morales Miriam M; Martin-Schild Sheryl; Abraham Anitha T; Walker Kyle C; Gonzales Nicole R; Illoh Kachikwu; Grotta James C; Savitz Sean I
The IVH score: a novel tool for estimating intraventricular hemorrhage volume: clinical and research implications.
Critical care medicine 2009;37(3):969-74, e1.
2009: Barreto Andrew D; Martin-Schild Sheryl; Hallevi Hen; Morales Miriam M; Abraham Anitha T; Gonzales Nicole R; Illoh Kachi; Grotta James C; Savitz Sean I
Thrombolytic therapy for patients who wake-up with stroke.
Stroke; a journal of cerebral circulation 2009;40(3):827-32.
2009: Martin-Schild Sheryl; Albright Karen C; Hallevi Hen; Barreto Andrew D; Grotta James C; Savitz Sean I
Does study enrollment delay treatment with intravenous thrombolytics for acute ischemic stroke?
Stroke; a journal of cerebral circulation 2009;40(2):663.
2009: Hallevi Hen; Albright Karen C; Martin-Schild Sheryl B; Barreto Andrew D; Morales Miriam M; Bornstein Natan; Ifejika Nneka L; Shuaib Ashfaq; Grotta James C; Savitz Sean I;
Recovery after ischemic stroke: criteria for good outcome by level of disability at day 7.
Cerebrovascular diseases (Basel, Switzerland) 2009;28(4):341-8.
2009: Harting Matthew T; Cox Charles S; Day Mary-Clare; Walker Peter; Gee Adrian; Brenneman Miranda M; Grotta James C; Savitz Sean I
Bone marrow-derived mononuclear cell populations in pediatric and adult patients.
Cytotherapy 2009;11(4):480-4.
2009: Albright Karen C; Raman Rema; Ernstrom Karin; Hallevi Hen; Martin-Schild Sheryl; Meyer Brett C; Meyer Dawn M; Morales Miriam M; Grotta James C; Lyden Patrick D; Savitz Sean I
Can comprehensive stroke centers erase the 'weekend effect'?
Cerebrovascular diseases (Basel, Switzerland) 2009;27(2):107-13.
2008: Barreto Andrew D; Albright Karen C; Hallevi Hen; Grotta James C; Noser Elizabeth A; Khaja Aslam M; Shaltoni Hashem M; Gonzales Nicole R; Illoh Kachi; Martin-Schild Sheryl; Campbell Morgan S; Weir Raymond U; Savitz Sean I
Thrombus burden is associated with clinical outcome after intra-arterial therapy for acute ischemic stroke.
Stroke; a journal of cerebral circulation 2008;39(12):3231-5.
2008: Martin-Schild Sheryl; Hallevi Hen; Albright Karen C; Khaja Aslam M; Barreto Andrew D; Gonzales Nicole R; Grotta James C; Savitz Sean I
Aggressive blood pressure-lowering treatment before intravenous tissue plasminogen activator therapy in acute ischemic stroke.
Archives of neurology 2008;65(9):1174-8.
2008: Hallevi Hen; Albright Karen C; Martin-Schild Sheryl; Barreto Andrew D; Savitz Sean I; Escobar Miguel A; Gonzales Nicole R; Noser Elizabeth A; Illoh Kachi; Grotta James C
Anticoagulation after cardioembolic stroke: to bridge or not to bridge?
Archives of neurology 2008;65(9):1169-73.
2008: Hallevi Hen; Grotta James C
Antiplatelet therapy and the risk of intracranial hemorrhage after intravenous tissue plasminogen activator therapy for acute ischemic stroke.
Archives of neurology 2008;65(5):575-6.
2008: Alexandrov Andrei V; Mikulik Robert; Ribo Marc; Sharma Vijay K; Lao Annabelle Y; Tsivgoulis Georgios; Sugg Rebecca M; Barreto Andrew; Sierzenski Paul; Malkoff Marc D; Grotta James C
A pilot randomized clinical safety study of sonothrombolysis augmentation with ultrasound-activated perflutren-lipid microspheres for acute ischemic stroke.
Stroke; a journal of cerebral circulation 2008;39(5):1464-9.
2008: Grotta James C; Jacobs Thomas P; Koroshetz Walter J; Moskowitz Michael A
Stroke program review group: an interim report.
Stroke; a journal of cerebral circulation 2008;39(4):1364-70.
2008: Hallevi Hen; Gonzales Nicole R; Barreto Andrew D; Martin-Schild Sheryl; Albright Karen C; Noser Elizabeth A; Illoh Kachi; Khaja Aslam M; Allison Teresa; Escobar Miguel A; Shaltoni Hashem M; Grotta James C
The effect of activated factor VII for intracerebral hemorrhage beyond 3 hours versus within 3 hours.
Stroke; a journal of cerebral circulation 2008;39(2):473-5.
2008: Meyer Dawn M; Albright Karen C; Allison Teresa A; Grotta James C
LOAD: a pilot study of the safety of loading of aspirin and clopidogrel in acute ischemic stroke and transient ischemic attack.
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2008;17(1):26-9.
2008: Hallevi Hen; Albright Karen C; Martin-Schild Sheryl; Barreto Andrew D; Grotta James C; Savitz Sean I
The complications of cardioembolic stroke: lessons from the VISTA database.
Cerebrovascular diseases (Basel, Switzerland) 2008;26(1):38-40.
2007: Zhao Xiurong; Sun Guanghua; Zhang Jie; Strong Roger; Dash Pramod K; Kan Yuet Wai; Grotta James C; Aronowski Jaroslaw
Transcription factor Nrf2 protects the brain from damage produced by intracerebral hemorrhage.
Stroke; a journal of cerebral circulation 2007;38(12):3280-6.
2007: Morgenstern Lewis B; Gonzales Nicole R; Maddox Katherine E; Brown Devin L; Karim Asha P; Espinosa Nina; Moyé Lemuel A; Pary Jennifer K; Grotta James C; Lisabeth Lynda D; Conley Kathleen M
A randomized, controlled trial to teach middle school children to recognize stroke and call 911: the kids identifying and defeating stroke project.
Stroke; a journal of cerebral circulation 2007;38(11):2972-8.
2007: Shuaib Ashfaq; Lees Kennedy R; Lyden Patrick; Grotta James; Davalos Antonio; Davis Stephen M; Diener Hans-Christoph; Ashwood Tim; Wasiewski Warren W; Emeribe Ugochi;
NXY-059 for the treatment of acute ischemic stroke.
The New England journal of medicine 2007;357(6):562-71.
2007: Lyden Patrick D; Shuaib Ashfaq; Lees Kennedy R; Davalos Antoni; Davis Stephen M; Diener Hans-Christoph; Grotta James C; Ashwood Tim J; Hardemark Hans-Goren; Svensson Hannah H; Rodichok Larry; Wasiewski Warren W; Ahlberg Gabrielle;
Safety and tolerability of NXY-059 for acute intracerebral hemorrhage: the CHANT Trial.
Stroke; a journal of cerebral circulation 2007;38(8):2262-9.
2007: Ali Myzoon; Bath Philip M W; Curram John; Davis Stephen M; Diener Hans-Christoph; Donnan Geoffrey A; Fisher Marc; Gregson Barbara A; Grotta James; Hacke Werner; Hennerici Michael G; Hommel Marc; Kaste Markku; Marler John R; Sacco Ralph L; Teal Philip; Wahlgren Nils-Gunnar; Warach Steven; Weir Christopher J; Lees Kennedy R
The Virtual International Stroke Trials Archive.
Stroke; a journal of cerebral circulation 2007;38(6):1905-10.
2007: Mikulik Robert; Ribo Marc; Hill Michael D; Grotta James C; Malkoff Marc; Molina Carlos; Rubiera Marta; Delgado-Mederos Raquel; Alvarez-Sabin Jose; Alexandrov Andrei V;
Accuracy of serial National Institutes of Health Stroke Scale scores to identify artery status in acute ischemic stroke.
Circulation 2007;115(20):2660-5.
2007: Zhao Xiurong; Zhang Yujian; Strong Roger; Zhang Jie; Grotta James C; Aronowski Jaroslaw
Distinct patterns of intracerebral hemorrhage-induced alterations in NF-kappaB subunit, iNOS, and COX-2 expression.
Journal of neurochemistry 2007;101(3):652-63.
2007: Zhao Xiurong; Sun Guanghua; Zhang Jie; Strong Roger; Song Weitao; Gonzales Nicole; Grotta James C; Aronowski Jaroslaw
Hematoma resolution as a target for intracerebral hemorrhage treatment: role for peroxisome proliferator-activated receptor gamma in microglia/macrophages.
Annals of neurology 2007;61(4):352-62.
2007: Hallevi Hen; Grotta James C
SITS-MOST: old myths laid to rest.
Lancet neurology 2007;6(4):292-3.
2007: Khaja Aslam M; Grotta James C
Established treatments for acute ischaemic stroke.
Lancet 2007;369(9558):319-30.
2007: Boake Corwin; Noser Elizabeth A; Ro Tony; Baraniuk Sarah; Gaber Mary; Johnson Ruth; Salmeron Eva T; Tran Thao M; Lai Jenny M; Taub Edward; Moye Lemuel A; Grotta James C; Levin Harvey S
Constraint-induced movement therapy during early stroke rehabilitation.
Neurorehabilitation and neural repair 2007;21(1):14-24.
2007: Shaltoni Hashem M; Albright Karen C; Gonzales Nicole R; Weir Raymond U; Khaja Aslam M; Sugg Rebecca M; Campbell Morgan S; Cacayorin Edwin D; Grotta James C; Noser Elizabeth A
Is intra-arterial thrombolysis safe after full-dose intravenous recombinant tissue plasminogen activator for acute ischemic stroke?
Stroke; a journal of cerebral circulation 2007;38(1):80-4.
2007: Grotta James; Marler John
Intravenous rt-PA: a tenth anniversary reflection.
Surgical neurology 2007;68 Suppl 1():S12-6.
2007: Gonzales Nicole R; Brown Devin L; Maddox Katherine E; Conley Kathleen M; Espinosa Nina; Pary Jennifer K; Karim Asha P; Moyé Lemuel A; Grotta James C; Morgenstern Lewis B
Kids Identifying and Defeating Stroke (KIDS): design of a school-based intervention to improve stroke awareness.
Ethnicity & disease 2007;17(2):320-6.
2007: Sylaja P N; Dong Wei; Grotta James C; Miller Mary K; Tomita Kristen; Hamilton Scott; Semba Charles; Hill Michael D
Safety outcomes of Alteplase among acute ischemic stroke patients with special characteristics.
Neurocritical care 2007;6(3):181-5.
2006: Pettigrew L Creed; Kasner Scott E; Albers Gregory W; Gorman Mark; Grotta James C; Sherman David G; Funakoshi Yosuke; Ishibashi Hideyasu;
Safety and tolerability of arundic acid in acute ischemic stroke.
Journal of the neurological sciences 2006;251(1-2):50-6.
2006: Lees Kennedy R; Davalos Antonio; Davis Stephen M; Diener Hans-Christoph; Grotta James; Lyden Patrick; Shuaib Ashfaq; Ashwood Tim; Hardemark Hans-Goran; Wasiewski Warren; Emeribe Ugochi; Zivin Justin A;
Additional outcomes and subgroup analyses of NXY-059 for acute ischemic stroke in the SAINT I trial.
Stroke; a journal of cerebral circulation 2006;37(12):2970-8.
2006: Sugg R M; Gonzales N R; Matherne D E; Ribo M; Shaltoni H M; Baraniuk S; Noser E A; Grotta J C
Myocardial injury in patients with intracerebral hemorrhage treated with recombinant factor VIIa.
Neurology 2006;67(6):1053-5.
2006: Sugg Rebecca M; Pary Jennifer K; Uchino Ken; Baraniuk Sarah; Shaltoni Hashem M; Gonzales Nicole R; Mikulik Robert; Garami Zsolt; Shaw Sandi G; Matherne Dawn E; Moyé Lemuel A; Alexandrov Andrei V; Grotta James C
Argatroban tPA stroke study: study design and results in the first treated cohort.
Archives of neurology 2006;63(8):1057-62.
2006: Ou Zhishuo; Zhao Xiurong; Labiche Lise A; Strong Roger; Grotta James C; Herrmann Oliver; Aronowski Jaroslaw
Neuronal expression of peroxisome proliferator-activated receptor-gamma (PPARgamma) and 15d-prostaglandin J2--mediated protection of brain after experimental cerebral ischemia in rat.
Brain research 2006;1096(1):196-203.
2006: Zhao Xiurong; Zhang Yujian; Strong Roger; Grotta James C; Aronowski Jaroslaw
15d-Prostaglandin J2 activates peroxisome proliferator-activated receptor-gamma, promotes expression of catalase, and reduces inflammation, behavioral dysfunction, and neuronal loss after intracerebral hemorrhage in rats.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2006;26(6):811-20.
2006: Gonzales Nicole R; Grotta James C
Alteplase for acute ischemic stroke.
Expert review of cardiovascular therapy 2006;4(3):301-18.
2006: Choi John Y; Porche Nichole A; Albright Karen C; Khaja Aslam M; Ho Victor S; Grotta James C
Using telemedicine to facilitate thrombolytic therapy for patients with acute stroke.
Joint Commission journal on quality and patient safety / Joint Commission Resources 2006;32(4):199-205.
2006: Sugg R M; Noser E A; Shaltoni H M; Gonzales N R; Campbell M S; Weir R; Cacayorin E D; Grotta J C
Intra-arterial reteplase compared to urokinase for thrombolytic recanalization in acute ischemic stroke.
AJNR. American journal of neuroradiology 2006;27(4):769-73.
2006: Grotta James C
Intracerebral hemorrhage: effective therapy at last?
International journal of stroke : official journal of the International Stroke Society 2006;1(1):30-1.
2006: Ro Tony; Noser Elizabeth; Boake Corwin; Johnson Ruth; Gaber Mary; Speroni Alda; Bernstein Michelle; De Joya Anna; Scott Burgin W; Zhang Lifang; Taub Edward; Grotta James C; Levin Harvey S
Functional reorganization and recovery after constraint-induced movement therapy in subacute stroke: case reports.
Neurocase : case studies in neuropsychology, neuropsychiatry, and behavioural neurology 2006;12(1):50-60.
2006: Lees Kennedy R; Zivin Justin A; Ashwood Tim; Davalos Antonio; Davis Stephen M; Diener Hans-Christoph; Grotta James; Lyden Patrick; Shuaib Ashfaq; Hårdemark Hans-Göran; Wasiewski Warren W;
NXY-059 for acute ischemic stroke.
The New England journal of medicine 2006;354(6):588-600.
2006: Zhao Xiurong; Ou Zhishuo; Grotta James C; Waxham Neal; Aronowski Jaroslaw
Peroxisome-proliferator-activated receptor-gamma (PPARgamma) activation protects neurons from NMDA excitotoxicity.
Brain research 2006;1073-1074():460-9.
2006: Ribo Marc; Grotta James C
Latest advances in intracerebral hemorrhage.
Current neurology and neuroscience reports 2006;6(1):17-22.
2006: Mikulik Robert; Alexandrov Andrei V; Ribo Marc; Garami Zsolt; Porche Nichole A; Fulep Eva; Grotta James C; Wojner-Alexandrov Anne W; Choi John Y
Telemedicine-guided carotid and transcranial ultrasound: a pilot feasibility study.
Stroke; a journal of cerebral circulation 2006;37(1):229-30.
2006: Choi John Y; Pary Jennifer K; Alexandrov Andrei V; Molina Carlos A; Garami Zsolt; Malkoff Marc D; Rubiera Marta; Shaltoni Hashem M; Moye Lemuel A; Grotta James C
Does clinical-CT 'mismatch' predict early response to treatment with recombinant tissue plasminogen activator?
Cerebrovascular diseases (Basel, Switzerland) 2006;22(5-6):384-8.
2005: Sugg Rebecca M; Malkoff Marc D; Noser Elizabeth A; Shaltoni Hashem M; Weir Raymond; Cacayorin Edwin D; Grotta James C
Endovascular recanalization of internal carotid artery occlusion in acute ischemic stroke.
AJNR. American journal of neuroradiology 2005;26(10):2591-4.
2005: Lyden Patrick; Raman Rema; Liu Lin; Grotta James; Broderick Joseph; Olson Scott; Shaw Sandi; Spilker Judith; Meyer Brett; Emr Marian; Warren Margo; Marler John
NIHSS training and certification using a new digital video disk is reliable.
Stroke; a journal of cerebral circulation 2005;36(11):2446-9.
2005: Fisher Marc; Albers Gregory W; Donnan Geoffrey A; Furlan Anthony J; Grotta James C; Kidwell Chelsea S; Sacco Ralph L; Wechsler Lawrence R;
Enhancing the development and approval of acute stroke therapies: Stroke Therapy Academic Industry roundtable.
Stroke; a journal of cerebral circulation 2005;36(8):1808-13.
2005: Wojner-Alexandrov Anne W; Alexandrov Andrei V; Rodriguez Diana; Persse David; Grotta James C
Houston paramedic and emergency stroke treatment and outcomes study (HoPSTO).
Stroke; a journal of cerebral circulation 2005;36(7):1512-8.
2005: Lu Mei; Lyden Patrick D; Brott Thomas G; Hamilton Scott; Broderick Joseph P; Grotta James C
Beyond subgroup analysis: improving the clinical interpretation of treatment effects in stroke research.
Journal of neuroscience methods 2005;143(2):209-16.
2005: Kwiatkowski Thomas; Libman Richard; Tilley Barbara C; Lewandowski Christopher; Grotta James C; Lyden Patrick; Levine Steven R; Brott Thomas;
The impact of imbalances in baseline stroke severity on outcome in the National Institute of Neurological Disorders and Stroke Recombinant Tissue Plasminogen Activator Stroke Study.
Annals of emergency medicine 2005;45(4):377-84.
2005: Libman Richard; Kwiakowski Thomas; Lyden Patrick; Grotta James C; Tilley Barbara C; Fagen Susan C; Levine Steven R; Broderick Joseph P; Lin Yan; Lewandowski Christopher; Frankel Micheal R;
Asymptomatic hemorrhagic transformation of cerebral infarction does not worsen long-term outcome.
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2005;14(2):50-4.
2005: Hall Christiana E; Grotta James C
New era for management of primary hypertensive intracerebral hemorrhage.
Current neurology and neuroscience reports 2005;5(1):29-35.
2005: Noser Elizabeth A; Shaltoni Hashem M; Hall Christiana E; Alexandrov Andrei V; Garami Zsolt; Cacayorin Edwin D; Song Joon K; Grotta James C; Campbell Morgan S
Aggressive mechanical clot disruption: a safe adjunct to thrombolytic therapy in acute stroke?
Stroke; a journal of cerebral circulation 2005;36(2):292-6.
2005: Zhao Xiurong; Liu Shi-Jie; Zhang Jie; Strong Roger; Aronowski Jarek; Grotta James C
Combining insulin-like growth factor derivatives plus caffeinol produces robust neuroprotection after stroke in rats.
Stroke; a journal of cerebral circulation 2005;36(1):129-34.
2005: Chernyshev Oleg Y; Garami Zsolt; Calleja Sergio; Song Joon; Campbell Morgan S; Noser Elizabeth A; Shaltoni Hashem; Chen Chin-I; Iguchi Yasuyuki; Grotta James C; Alexandrov Andrei V
Yield and accuracy of urgent combined carotid/transcranial ultrasound testing in acute cerebral ischemia.
Stroke; a journal of cerebral circulation 2005;36(1):32-7.
2005: Chen Chin-I; Iguchi Yasuyuki; Grotta James C; Garami Zsolt; Uchino Ken; Shaltoni Hashem; Alexandrov Andrei V
Intravenous TPA for very old stroke patients.
European neurology 2005;54(3):140-4.
2005: Zhao Xiurong; Aronowski Jaroslaw; Liu Shi-Jie; Schallert Timothy; Zhang Jie; Strong Roger; Ou Zhi-Shuo; Nguyen Theresa; Grotta James C
Wheel-running modestly promotes functional recovery after a unilateral cortical lesion in rats.
Behavioural neurology 2005;16(1):41-9.
2005: Uchino Ken; Alexandrov Andrei V; Garami Zsolt; El-Mitwalli Ashraf; Morgenstern Lewis B; Grotta James C
Safety and feasibility of a lower dose intravenous TPA therapy for ischemic stroke beyond the first three hours.
Cerebrovascular diseases (Basel, Switzerland) 2005;19(4):260-6.
2004: Alexandrov Andrei V; Molina Carlos A; Grotta James C; Garami Zsolt; Ford Shiela R; Alvarez-Sabin Jose; Montaner Joan; Saqqur Maher; Demchuk Andrew M; Moyé Lemuel A; Hill Michael D; Wojner Anne W;
Ultrasound-enhanced systemic thrombolysis for acute ischemic stroke.
The New England journal of medicine 2004;351(21):2170-8.
2004: Grotta James C; Noser Elizabeth A; Ro Tony; Boake Corwin; Levin Harvey; Aronowski Jarek; Schallert Timothy
Constraint-induced movement therapy.
Stroke; a journal of cerebral circulation 2004;35(11 Suppl 1):2699-701.
2004: Al-Senani Fahmi M; Graffagnino Carmelo; Grotta James C; Saiki Robin; Wood Denise; Chung William; Palmer Grant; Collins Ken A
A prospective, multicenter pilot study to evaluate the feasibility and safety of using the CoolGard System and Icy catheter following cardiac arrest.
Resuscitation 2004;62(2):143-50.
2004: Alexandrov Andrei V; Demchuk Andrew M; Burgin W Scott; Robinson David J; Grotta James C;
Ultrasound-enhanced thrombolysis for acute ischemic stroke: phase I. Findings of the CLOTBUST trial.
Journal of neuroimaging : official journal of the American Society of Neuroimaging 2004;14(2):113-7.
2004: Alexandrov Andrei V; Wojner Anne W; Grotta James C;
CLOTBUST: design of a randomized trial of ultrasound-enhanced thrombolysis for acute ischemic stroke.
Journal of neuroimaging : official journal of the American Society of Neuroimaging 2004;14(2):108-12.
2004: Hacke Werner; Donnan Geoffrey; Fieschi Cesare; Kaste Markku; von Kummer Rüdiger; Broderick Joseph P; Brott Thomas; Frankel Michael; Grotta James C; Haley E Clarke; Kwiatkowski Thomas; Levine Steven R; Lewandowski Chris; Lu Mei; Lyden Patrick; Marler John R; Patel Suresh; Tilley Barbara C; Albers Gregory; Bluhmki Erich; Wilhelm Manfred; Hamilton Scott;
Association of outcome with early stroke treatment: pooled analysis of ATLANTIS, ECASS, and NINDS rt-PA stroke trials.
Lancet 2004;363(9411):768-74.
2004: Alexandrov Andrei V; Hall Christiana E; Labiche Lise A; Wojner Anne W; Grotta James C
Ischemic stunning of the brain: early recanalization without immediate clinical improvement in acute ischemic stroke.
Stroke; a journal of cerebral circulation 2004;35(2):449-52.
2004: Labiche Lise A; Grotta James C
Clinical trials for cytoprotection in stroke.
NeuroRx : the journal of the American Society for Experimental NeuroTherapeutics 2004;1(1):46-70.
2004: Cramer Steven C; Rordorf Guy; Maki Jeffrey H; Kramer Larry A; Grotta James C; Burgin W Scott; Hinchey Judith A; Benesch Curtis; Furie Karen L; Lutsep Helmi L; Kelly Ellen; Longstreth W T
Increased pelvic vein thrombi in cryptogenic stroke: results of the Paradoxical Emboli from Large Veins in Ischemic Stroke (PELVIS) study.
Stroke; a journal of cerebral circulation 2004;35(1):46-50.
2004: Piriyawat Paisith; Morgenstern Lewis B; Yawn David H; Hall Christiana E; Grotta James C
Treatment of acute intracerebral hemorrhage with epsilon-aminocaproic acid: a pilot study.
Neurocritical care 2004;1(1):47-51.
2003: Morgenstern Lewis B; Bartholomew L Kay; Grotta James C; Staub Lara; King Mary; Chan Wenyaw
Sustained benefit of a community and professional intervention to increase acute stroke therapy.
Archives of internal medicine 2003;163(18):2198-202.
2003: Wojner Anne W; Morgenstern Lewis; Alexandrov Andrei V; Rodriguez Diana; Persse David; Grotta James C
Paramedic and emergency department care of stroke: baseline data from a citywide performance improvement study.
American journal of critical care : an official publication, American Association of Critical-Care Nurses 2003;12(5):411-7.
2003: Grotta James
NIHSS/EIC mismatch explains the >1/3 MCA conundrum.
Stroke; a journal of cerebral circulation 2003;34(9):e148-9; author reply e148-9.
2003: Cramer Steven C; Maki Jeffrey H; Waitches Gayle M; D'Souza Neisha; Grotta James C; Burgin W Scott; Kramer Larry A
Paradoxical emboli from calf and pelvic veins in cryptogenic stroke.
Journal of neuroimaging : official journal of the American Society of Neuroimaging 2003;13(3):218-23.
2003: Grotta James C
Adding to the effectiveness of intravenous tissue plasminogen activator for treating acute stroke.
Circulation 2003;107(22):2769-70.
2003: Piriyawat Paisith; Labiche Lise A; Burgin W Scott; Aronowski Jaroslaw A; Grotta James C
Pilot dose-escalation study of caffeine plus ethanol (caffeinol) in acute ischemic stroke.
Stroke; a journal of cerebral circulation 2003;34(5):1242-5.
2003: Aronowski Jaroslaw; Strong Roger; Shirzadi Ali; Grotta James C
Ethanol plus caffeine (caffeinol) for treatment of ischemic stroke: preclinical experience.
Stroke; a journal of cerebral circulation 2003;34(5):1246-51.
2003: Labiche Lise A; Al-Senani Fahmi; Wojner Anne W; Grotta James C; Malkoff Marc; Alexandrov Andrei V
Is the benefit of early recanalization sustained at 3 months? A prospective cohort study.
Stroke; a journal of cerebral circulation 2003;34(3):695-8.
2002: Wein Theodore H; Hickenbottom Susan L; Morgenstern Lewis B; Demchuk Andrew M; Grotta James C
Safety of tissue plasminogen activator for acute stroke in menstruating women.
Stroke; a journal of cerebral circulation 2002;33(10):2506-8.
2002: Alexandrov Andrei V; Grotta James C
Arterial reocclusion in stroke patients treated with intravenous tissue plasminogen activator.
Neurology 2002;59(6):862-7.
2002: Song Joon K; Cacayorin Edwin D; Campbell Morgan S; Fisher Stanley; Malkoff Marc D; Alexandrov Andrei V; Grotta James C
Intracranial balloon angioplasty of acute terminal internal carotid artery occlusions.
AJNR. American journal of neuroradiology 2002;23(8):1308-12.
2002: Al-Senani Fahmi M; Grotta James C
Neuroprotection after cardiac arrest.
Lancet neurology 2002;1(3):146.
2002: Grotta James C;
The NINDS stroke study group response.
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2002;11(3-4):121-4.
2002: Felberg Robert A; Okon Nicholas J; El-Mitwalli Ashraf; Burgin W Scott; Grotta James C; Alexandrov Andrei V
Early dramatic recovery during intravenous tissue plasminogen activator infusion: clinical pattern and outcome in acute middle cerebral artery stroke.
Stroke; a journal of cerebral circulation 2002;33(5):1301-7.
2002: Christou Ioannis; Felberg Robert A; Demchuk Andrew M; Burgin W Scott; Malkoff Marc; Grotta James C; Alexandrov Andrei V
Intravenous tissue plasminogen activator and flow improvement in acute ischemic stroke patients with internal carotid artery occlusion.
Journal of neuroimaging : official journal of the American Society of Neuroimaging 2002;12(2):119-23.
2002: Felberg Robert A; Grotta James C; Shirzadi Ali L; Strong Roger; Narayana Ponnada; Hill-Felberg Sandra J; Aronowski Jaroslaw
Cell death in experimental intracerebral hemorrhage: the "black hole" model of hemorrhagic damage.
Annals of neurology 2002;51(4):517-24.
2002: Grotta James
Neuroprotection is unlikely to be effective in humans using current trial designs.
Stroke; a journal of cerebral circulation 2002;33(1):306-7.
2002: Morgenstern Lewis B; Staub Lara; Chan Wenyaw; Wein Theodore H; Bartholomew L Kay; King Mary; Felberg Robert A; Burgin W Scott; Groff Janet; Hickenbottom Susan L; Saldin Kamaldeen; Demchuk Andrew M; Kalra Anjali; Dhingra Anupma; Grotta James C
Improving delivery of acute stroke therapy: The TLL Temple Foundation Stroke Project.
Stroke; a journal of cerebral circulation 2002;33(1):160-6.
2002: Kasner Scott E; Wein Theodore; Piriyawat Paisith; Villar-Cordova Carlos E; Chalela Julio A; Krieger Derk W; Morgenstern Lewis B; Kimmel Stephen E; Grotta James C
Acetaminophen for altering body temperature in acute stroke: a randomized clinical trial.
Stroke; a journal of cerebral circulation 2002;33(1):130-4.
2001: Burgin W S; Staub L; Chan W; Wein T H; Felberg R A; Grotta J C; Demchuk A M; Hickenbottom S L; Morgenstern L B
Acute stroke care in non-urban emergency departments.
Neurology 2001;57(11):2006-12.
2001: Grotta J C; Burgin W S; El-Mitwalli A; Long M; Campbell M; Morgenstern L B; Malkoff M; Alexandrov A V
Intravenous tissue-type plasminogen activator therapy for ischemic stroke: Houston experience 1996 to 2000.
Archives of neurology 2001;58(12):2009-13.
2001: Patel S C; Levine S R; Tilley B C; Grotta J C; Lu M; Frankel M; Haley E C; Brott T G; Broderick J P; Horowitz S; Lyden P D; Lewandowski C A; Marler J R; Welch K M;
Lack of clinical significance of early ischemic changes on computed tomography in acute stroke.
JAMA : the journal of the American Medical Association 2001;286(22):2830-8.
2001: Bland S T; Pillai R N; Aronowski J; Grotta J C; Schallert T
Early overuse and disuse of the affected forelimb after moderately severe intraluminal suture occlusion of the middle cerebral artery in rats.
Behavioural brain research 2001;126(1-2):33-41.
2001: Felberg R A; Krieger D W; Chuang R; Persse D E; Burgin W S; Hickenbottom S L; Morgenstern L B; Rosales O; Grotta J C
Hypothermia after cardiac arrest: feasibility and safety of an external cooling protocol.
Circulation 2001;104(15):1799-804.
2001: Christou I; Burgin W S; Alexandrov A V; Grotta J C
Arterial status after intravenous TPA therapy for ischaemic stroke. A need for further interventions.
International angiology : a journal of the International Union of Angiology 2001;20(3):208-13.
2001: Christou I; Felberg R A; Demchuk A M; Grotta J C; Burgin W S; Malkoff M; Alexandrov A V
A broad diagnostic battery for bedside transcranial Doppler to detect flow changes with internal carotid artery stenosis or occlusion.
Journal of neuroimaging : official journal of the American Society of Neuroimaging 2001;11(3):236-42.
2001: Morgenstern L B; Huber J C; Luna-Gonzales H; Saldin K R; Grotta J C; Shaw S G; Knudson L; Frankowski R F
Headache in the emergency department.
Headache 2001;41(6):537-41.
2001: Alexandrov A V; Burgin W S; Demchuk A M; El-Mitwalli A; Grotta J C
Speed of intracranial clot lysis with intravenous tissue plasminogen activator therapy: sonographic classification and short-term improvement.
Circulation 2001;103(24):2897-902.
2001: Broderick J; Lu M; Jackson C; Pancioli A; Tilley B C; Fagan S C; Kothari R; Levine S R; Marler J R; Lyden P D; Haley E C; Brott T; Grotta J C;
Apolipoprotein E phenotype and the efficacy of intravenous tissue plasminogen activator in acute ischemic stroke.
Annals of neurology 2001;49(6):736-44.
2001: Morgenstern L B; Demchuk A M; Kim D H; Frankowski R F; Grotta J C
Rebleeding leads to poor outcome in ultra-early craniotomy for intracerebral hemorrhage.
Neurology 2001;56(10):1294-9.
2001: Derex L; Tomsick T A; Brott T G; Lewandowski C A; Frankel M R; Clark W; Starkman S; Spilker J; Udsten G J; Khoury J; Grotta J C; Broderick J P;
Outcome of stroke patients without angiographically revealed arterial occlusion within four hours of symptom onset.
AJNR. American journal of neuroradiology 2001;22(4):685-90.
2001: Grotta J C; Welch K M; Fagan S C; Lu M; Frankel M R; Brott T; Levine S R; Lyden P D
Clinical deterioration following improvement in the NINDS rt-PA Stroke Trial.
Stroke; a journal of cerebral circulation 2001;32(3):661-8.
2000: Marler J R; Tilley B C; Lu M; Brott T G; Lyden P C; Grotta J C; Broderick J P; Levine S R; Frankel M P; Horowitz S H; Haley E C; Lewandowski C A; Kwiatkowski T P
Early stroke treatment associated with better outcome: the NINDS rt-PA stroke study.
Neurology 2000;55(11):1649-55.
2000: Broderick J P; Lu M; Kothari R; Levine S R; Lyden P D; Haley E C; Brott T G; Grotta J; Tilley B C; Marler J R; Frankel M
Finding the most powerful measures of the effectiveness of tissue plasminogen activator in the NINDS tPA stroke trial.
Stroke; a journal of cerebral circulation 2000;31(10):2335-41.
2000: Wein T H; Staub L; Felberg R; Hickenbottom S L; Chan W; Grotta J C; Demchuk A M; Groff J; Bartholomew L K; Morgenstern L B
Activation of emergency medical services for acute stroke in a nonurban population: the T.L.L. Temple Foundation Stroke Project.
Stroke; a journal of cerebral circulation 2000;31(8):1925-8.
2000: Christou I; Alexandrov A V; Burgin W S; Wojner A W; Felberg R A; Malkoff M; Grotta J C
Timing of recanalization after tissue plasminogen activator therapy determined by transcranial doppler correlates with clinical recovery from ischemic stroke.
Stroke; a journal of cerebral circulation 2000;31(8):1812-6.
2000: Aronowski J; Strong R; Kang H S; Grotta J C
Selective up-regulation of I kappaB-alpha in ischemic penumbra following focal cerebral ischemia.
Neuroreport 2000;11(7):1529-33.
2000: Bland S T; Schallert T; Strong R; Aronowski J; Grotta J C; Feeney D M
Early exclusive use of the affected forelimb after moderate transient focal ischemia in rats : functional and anatomic outcome.
Stroke; a journal of cerebral circulation 2000;31(5):1144-52.
2000: Burgin W S; Malkoff M; Felberg R A; Demchuk A M; Christou I; Grotta J C; Alexandrov A V
Transcranial doppler ultrasound criteria for recanalization after thrombolysis for middle cerebral artery stroke.
Stroke; a journal of cerebral circulation 2000;31(5):1128-32.
2000: Alexandrov A V; Felberg R A; Demchuk A M; Christou I; Burgin W S; Malkoff M; Wojner A W; Grotta J C
Deterioration following spontaneous improvement : sonographic findings in patients with acutely resolving symptoms of cerebral ischemia.
Stroke; a journal of cerebral circulation 2000;31(4):915-9.
2000: Felberg R A; Burgin W S; Grotta J C
Neuroprotection and the ischemic cascade.
CNS spectrums 2000;5(3):52-8.
2000: Alexandrov A V; Demchuk A M; Felberg R A; Christou I; Barber P A; Burgin W S; Malkoff M; Wojner A W; Grotta J C
High rate of complete recanalization and dramatic clinical recovery during tPA infusion when continuously monitored with 2-MHz transcranial doppler monitoring.
Stroke; a journal of cerebral circulation 2000;31(3):610-4.
2000: Aronowski J; Grotta J C; Strong R; Waxham M N
Interplay between the gamma isoform of PKC and calcineurin in regulation of vulnerability to focal cerebral ischemia.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2000;20(2):343-9.
2000: Strong R; Grotta J C; Aronowski J
Combination of low dose ethanol and caffeine protects brain from damage produced by focal ischemia in rats.
Neuropharmacology 2000;39(3):515-22.
2000: Alexandrov A V; Demchuk A M; Felberg R A; Grotta J C; Krieger D W
Intracranial clot dissolution is associated with embolic signals on transcranial Doppler.
Journal of neuroimaging : official journal of the American Society of Neuroimaging 2000;10(1):27-32.
2000: Demchuk A M; Christou I; Wein T H; Felberg R A; Malkoff M; Grotta J C; Alexandrov A V
Accuracy and criteria for localizing arterial occlusion with transcranial Doppler.
Journal of neuroimaging : official journal of the American Society of Neuroimaging 2000;10(1):1-12.
2000: Demchuk A M; Christou I; Wein T H; Felberg R A; Malkoff M; Grotta J C; Alexandrov A V
Specific transcranial Doppler flow findings related to the presence and site of arterial occlusion.
Stroke; a journal of cerebral circulation 2000;31(1):140-6.
1999: Lewandowski C A; Frankel M; Tomsick T A; Broderick J; Frey J; Clark W; Starkman S; Grotta J; Spilker J; Khoury J; Brott T
Combined intravenous and intra-arterial r-TPA versus intra-arterial therapy of acute ischemic stroke: Emergency Management of Stroke (EMS) Bridging Trial.
Stroke; a journal of cerebral circulation 1999;30(12):2598-605.
1999: Hickenbottom S L; Grotta J C; Strong R; Denner L A; Aronowski J
Nuclear factor-kappaB and cell death after experimental intracerebral hemorrhage in rats.
Stroke; a journal of cerebral circulation 1999;30(11):2472-7; discussion 2477-8.
1999: Woo D; Broderick J P; Kothari R U; Lu M; Brott T; Lyden P D; Marler J R; Grotta J C
Does the National Institutes of Health Stroke Scale favor left hemisphere strokes? NINDS t-PA Stroke Study Group.
Stroke; a journal of cerebral circulation 1999;30(11):2355-9.
1999: Grotta J C
Acute stroke therapy at the millennium: consummating the marriage between the laboratory and bedside. The Feinberg lecture.
Stroke; a journal of cerebral circulation 1999;30(8):1722-8.
1999: Alexandrov A V; Demchuk A M; Wein T H; Grotta J C
Yield of transcranial Doppler in acute cerebral ischemia.
Stroke; a journal of cerebral circulation 1999;30(8):1604-9.
1999: Grotta J C; Chiu D; Lu M; Patel S; Levine S R; Tilley B C; Brott T G; Haley E C; Lyden P D; Kothari R; Frankel M; Lewandowski C A; Libman R; Kwiatkowski T; Broderick J P; Marler J R; Corrigan J; Huff S; Mitsias P; Talati S; Tanne D
Agreement and variability in the interpretation of early CT changes in stroke patients qualifying for intravenous rtPA therapy.
Stroke; a journal of cerebral circulation 1999;30(8):1528-33.
1999: Aronowski J; Cho K H; Strong R; Grotta J C
Neurofilament proteolysis after focal ischemia; when do cells die after experimental stroke?
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1999;19(6):652-60.
1999: Grotta J C; Helgason C
Ischemic stroke pathophysiology.
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 1999;8(3):114-6.
1999: Demchuk A M; Morgenstern L B; Krieger D W; Linda Chi T; Hu W; Wein T H; Hardy R J; Grotta J C; Buchan A M
Serum glucose level and diabetes predict tissue plasminogen activator-related intracerebral hemorrhage in acute ischemic stroke.
Stroke; a journal of cerebral circulation 1999;30(1):34-9.
1998: Kasner S E; Gurian J H; Grotta J C
Urokinase treatment of sagittal sinus thrombosis with venous hemorrhagic infarction.
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 1998;7(6):421-5.
1998: Morgenstern L B; Frankowski R F; Shedden P; Pasteur W; Grotta J C
Surgical treatment for intracerebral hemorrhage (STICH): a single-center, randomized clinical trial.
Neurology 1998;51(5):1359-63.
1998: Morgenstern L B; Luna-Gonzales H; Huber J C; Wong S S; Uthman M O; Gurian J H; Castillo P R; Shaw S G; Frankowski R F; Grotta J C
Worst headache and subarachnoid hemorrhage: prospective, modern computed tomography and spinal fluid analysis.
Annals of emergency medicine 1998;32(3 Pt 1):297-304.
1998: Brott T; Lu M; Kothari R; Fagan S C; Frankel M; Grotta J C; Broderick J; Kwiatkowski T; Lewandowski C; Haley E C; Marler J R; Tilley B C
Hypertension and its treatment in the NINDS rt-PA Stroke Trial.
Stroke; a journal of cerebral circulation 1998;29(8):1504-9.
1998: Chiu D; Grotta J C; Krieger D; Kasner S; Villar C; Bratina P; Vital D
Discussion of mitchell JB, Ballard DJ, whisnant JP, et al. What role do neurologists play in determining the costs and outcome of stroke patients? stroke 1996;27:1937-1943.
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 1998;7(4):267-71.
1998: Chiu D; Shedden P; Bratina P; Grotta J C
Clinical features of moyamoya disease in the United States.
Stroke; a journal of cerebral circulation 1998;29(7):1347-51.
1998: Kasner S E; Villar-Cordova C E; Tong D; Grotta J C
Hemopericardium and cardiac tamponade after thrombolysis for acute ischemic stroke.
Neurology 1998;50(6):1857-9.
1998: Villar-Cordova C; Morgenstern L B; Barnholtz J S; Frankowski R F; Grotta J C
Neurologists' attitudes regarding rt-PA for acute ischemic stroke.
Neurology 1998;50(5):1491-4.
1998: Grotta J C; Alexandrov A V
tPA-associated reperfusion after acute stroke demonstrated by SPECT.
Stroke; a journal of cerebral circulation 1998;29(2):429-32.
1998: Chiu D; Krieger D; Villar-Cordova C; Kasner S E; Morgenstern L B; Bratina P L; Yatsu F M; Grotta J C
Intravenous tissue plasminogen activator for acute ischemic stroke: feasibility, safety, and efficacy in the first year of clinical practice.
Stroke; a journal of cerebral circulation 1998;29(1):18-22.
1998: Hickenbottom S L; Grotta J
Neuroprotective therapy.
Seminars in neurology 1998;18(4):485-92.
1997: Grotta J
Lubeluzole treatment of acute ischemic stroke. The US and Canadian Lubeluzole Ischemic Stroke Study Group.
Stroke; a journal of cerebral circulation 1997;28(12):2338-46.
1997: Kasner S E; Grotta J C
Emergency identification and treatment of acute ischemic stroke.
Annals of emergency medicine 1997;30(5):642-53.
1997: Aronowski J; Strong R; Grotta J C
Reperfusion injury: demonstration of brain damage produced by reperfusion after transient focal ischemia in rats.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1997;17(10):1048-56.
1997: Grotta J
Should thrombolytic therapy be the first-line treatment for acute ischemic stroke? t-PA--the best current option for most patients.
The New England journal of medicine 1997;337(18):1310-3.
1997: Krieger D; Kasner S E; Grotta J C
Mechanical ventilation.
Neurology 1997;49(1):311; author reply 311-2.
1997: Grotta J
Cerebrovascular disease in young patients.
Thrombosis and haemostasis 1997;78(1):13-23.
1997: Alexandrov A V; Vital D; Brodie D S; Hamilton P; Grotta J C
Grading carotid stenosis with ultrasound. An interlaboratory comparison.
Stroke; a journal of cerebral circulation 1997;28(6):1208-10.
1997: Morgenstern L B; Fox A J; Sharpe B L; Eliasziw M; Barnett H J; Grotta J C
The risks and benefits of carotid endarterectomy in patients with near occlusion of the carotid artery. North American Symptomatic Carotid Endarterectomy Trial (NASCET) Group.
Neurology 1997;48(4):911-5.
1996: Aronowski J; Strong R; Grotta J C
Citicoline for treatment of experimental focal ischemia: histologic and behavioral outcome.
Neurological research 1996;18(6):570-4.
1996: Tilley B C; Marler J; Geller N L; Lu M; Legler J; Brott T; Lyden P; Grotta J
Use of a global test for multiple outcomes in stroke trials with application to the National Institute of Neurological Disorders and Stroke t-PA Stroke Trial.
Stroke; a journal of cerebral circulation 1996;27(11):2136-42.
1996: Grotta J
Rodent models of stroke limitations. What can we learn from recent clinical trials of thrombolysis?
Archives of neurology 1996;53(10):1067-70.
1996: Sills C; Villar-Cordova C; Pasteur W; Ramirez A; Lamki L; Barron B; Mullani N; Grotta J
Demonstration of hypoperfusion surrounding intracerebral hematoma in humans.
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 1996;6(1):17-24.
1996: Adams H P; Brott T G; Furlan A J; Gomez C R; Grotta J; Helgason C M; Kwiatkowski T; Lyden P D; Marler J R; Torner J; Feinberg W; Mayberg M; Thies W
Guidelines for thrombolytic therapy for acute stroke: a supplement to the guidelines for the management of patients with acute ischemic stroke. A statement for healthcare professionals from a Special Writing Group of the Stroke Council, American Heart Association.
Circulation 1996;94(5):1167-74.
1996: Adams H P; Brott T G; Furlan A J; Gomez C R; Grotta J; Helgason C M; Kwiatkowski T; Lyden P D; Marler J R; Torner J; Feinberg W; Mayberg M; Thies W
Guidelines for Thrombolytic Therapy for Acute Stroke: a Supplement to the Guidelines for the Management of Patients with Acute Ischemic Stroke. A statement for healthcare professionals from a Special Writing Group of the Stroke Council, American Heart Association.
Stroke; a journal of cerebral circulation 1996;27(9):1711-8.
1996: Aronowski J; Strong R; Grotta J C
Combined neuroprotection and reperfusion therapy for stroke. Effect of lubeluzole and diaspirin cross-linked hemoglobin in experimental focal ischemia.
Stroke; a journal of cerebral circulation 1996;27(9):1571-6; discussion 1576-7.
1996: Aronowski J; Samways E; Strong R; Rhoades H M; Grotta J C
An alternative method for the quantitation of neuronal damage after experimental middle cerebral artery occlusion in rats: analysis of behavioral deficit.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1996;16(4):705-13.
1996: Aronowski J; Strong R; Grotta J C
Treatment of experimental focal ischemia in rats with lubeluzole.
Neuropharmacology 1996;35(6):689-93.
1996: Aronowski J; Grotta J C
Ca2+/calmodulin-dependent protein kinase II in postsynaptic densities after reversible cerebral ischemia in rats.
Brain research 1996;709(1):103-10.
1996: Waxham M N; Grotta J C; Silva A J; Strong R; Aronowski J
Ischemia-induced neuronal damage: a role for calcium/calmodulin-dependent protein kinase II.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1996;16(1):1-6.
1995: Grotta J; Pasteur W; Khwaja G; Hamel T; Fisher M; Ramirez A
Elective intubation for neurologic deterioration after stroke.
Neurology 1995;45(4):640-4.
1995: Grotta J; Clark W; Coull B; Pettigrew L C; Mackay B; Goldstein L B; Meissner I; Murphy D; LaRue L
Safety and tolerability of the glutamate antagonist CGS 19755 (Selfotel) in patients with acute ischemic stroke. Results of a phase IIa randomized trial.
Stroke; a journal of cerebral circulation 1995;26(4):602-5.
1995: Bratina P; Greenberg L; Pasteur W; Grotta J C
Current emergency department management of stroke in Houston, Texas.
Stroke; a journal of cerebral circulation 1995;26(3):409-14.
1995: Grotta J
Why do all drugs work in animals but none in stroke patients? 2. Neuroprotective therapy.
Journal of internal medicine 1995;237(1):89-94.
1994: Lyden P; Brott T; Tilley B; Welch K M; Mascha E J; Levine S; Haley E C; Grotta J; Marler J
Improved reliability of the NIH Stroke Scale using video training. NINDS TPA Stroke Study Group.
Stroke; a journal of cerebral circulation 1994;25(11):2220-6.
1994: Aronowski J; Ostrow P; Samways E; Strong R; Zivin J A; Grotta J C
Graded bioassay for demonstration of brain rescue from experimental acute ischemia in rats.
Stroke; a journal of cerebral circulation 1994;25(11):2235-40.
1994: Adams H P; Brott T G; Crowell R M; Furlan A J; Gomez C R; Grotta J; Helgason C M; Marler J R; Woolson R F; Zivin J A
Guidelines for the management of patients with acute ischemic stroke. A statement for healthcare professionals from a special writing group of the Stroke Council, American Heart Association.
Circulation 1994;90(3):1588-601.
1994: Adams H P; Brott T G; Crowell R M; Furlan A J; Gomez C R; Grotta J; Helgason C M; Marler J R; Woolson R F; Zivin J A
Guidelines for the management of patients with acute ischemic stroke. A statement for healthcare professionals from a special writing group of the Stroke Council, American Heart Association.
Stroke; a journal of cerebral circulation 1994;25(9):1901-14.
1994: DeGraba T J; Ostrow P; Hanson S; Grotta J C
Motor performance, histologic damage, and calcium influx in rats treated with NBQX after focal ischemia.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1994;14(2):262-8.
1994: Hanson S K; Grotta J C; Waxham M N; Aronowski J; Ostrow P
Calcium/calmodulin-dependent protein kinase II activity in focal ischemia with reperfusion in rats.
Stroke; a journal of cerebral circulation 1994;25(2):466-73.
1994: Lisk D R; Pasteur W; Rhoades H; Putnam R D; Grotta J C
Early presentation of hemispheric intracerebral hemorrhage: prediction of outcome and guidelines for treatment allocation.
Neurology 1994;44(1):133-9.
1993: Fisher M; Grotta J
New uses for calcium channel blockers. Therapeutic implications.
Drugs 1993;46(6):961-75.
1993: Hanson S K; Grotta J C; Rhoades H; Tran H D; Lamki L M; Barron B J; Taylor W J
Value of single-photon emission-computed tomography in acute stroke therapeutic trials.
Stroke; a journal of cerebral circulation 1993;24(9):1322-9.
1993: Lisk D R; Grotta J C; Lamki L M; Tran H D; Taylor J W; Molony D A; Barron B J
Should hypertension be treated after acute stroke? A randomized controlled trial using single photon emission computed tomography.
Archives of neurology 1993;50(8):855-62.
1993: DeGraba T J; Ostrow P T; Grotta J C
Threshold of calcium disturbances after focal cerebral ischemia in rats. Implications of the window of therapeutic opportunity.
Stroke; a journal of cerebral circulation 1993;24(8):1212-6; discussion 1216-7.
1993: Aronowski J; Waxham M N; Grotta J C
Neuronal protection and preservation of calcium/calmodulin-dependent protein kinase II and protein kinase C activity by dextrorphan treatment in global ischemia.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1993;13(4):550-7.
1992: DeGraba T J; Ostrow P T; Strong R A; Earls R M; Zong Z J; Grotta J C
Temporal relation of calcium-calmodulin binding and neuronal damage after global ischemia in rats.
Stroke; a journal of cerebral circulation 1992;23(6):876-82.
1992: Aronowski J; Grotta J C; Waxham M N
Ischemia-induced translocation of Ca2+/calmodulin-dependent protein kinase II: potential role in neuronal damage.
Journal of neurochemistry 1992;58(5):1743-53.
1992: Grotta J C; Norris J W; Kamm B
Prevention of stroke with ticlopidine: who benefits most? TASS Baseline and Angiographic Data Subgroup.
Neurology 1992;42(1):111-5.
1991: Rosenbaum D; Zabramski J; Frey J; Yatsu F; Marler J; Spetzler R; Grotta J
Early treatment of ischemic stroke with a calcium antagonist.
Stroke; a journal of cerebral circulation 1991;22(4):437-41.
1991: Olsen M L; O'Connor S; Arnett F C; Rosenbaum D; Grotta J C; Warner N B
Autoantibodies and rheumatic disorders in a neurology inpatient population: a prospective study.
The American journal of medicine 1991;90(4):479-88.
1990: Rosenbaum D M; Grotta J C; Yatsu F M; Picone C M; Pettigrew L C; Bratina P; Zabramski J; Spetzler R; Lopez L; Marler J
Pilot study of nicardipine for acute ischemic stroke.
Angiology 1990;41(11 Pt 2):1017-22.
1990: Grotta J C; Picone C M; Dedman J R; Rhoades H M; Strong R A; Earls R M; Yao L P
Neuronal protection correlates with prevention of calcium-calmodulin binding in rats.
Stroke; a journal of cerebral circulation 1990;21(11 Suppl):III28-31.
1990: Zivin J A; Grotta J C
Animal stroke models. They are relevant to human disease.
Stroke; a journal of cerebral circulation 1990;21(7):981-3.
1990: Grotta J C; Picone C M; Earls R; Strong R; Yao L; Dedman J R
Calcium-calmodulin binding in ischemic rat neurons after calcium channel blocker therapy.
Stroke; a journal of cerebral circulation 1990;21(6):948-52.
1990: Grotta J C; Picone C M; Ostrow P T; Strong R A; Earls R M; Yao L P; Rhoades H M; Dedman J R
CGS-19755, a competitive NMDA receptor antagonist, reduces calcium-calmodulin binding and improves outcome after global cerebral ischemia.
Annals of neurology 1990;27(6):612-9.
1990: Rosenbaum D M; Grotta J C; Pettigrew L C; Ostrow P; Strong R; Rhoades H; Picone C M; Grotta A T
Baclofen does not protect against cerebral ischemia in rats.
Stroke; a journal of cerebral circulation 1990;21(1):138-40.
1989: Picone C M; Grotta J C; Earls R; Strong R; Dedman J
Immunohistochemical determination of calcium-calmodulin binding predicts neuronal damage after global ischemia.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1989;9(6):805-11.
1989: Grotta J C; Yatsu F M; Pettigrew L C; Rhoades H; Bratina P; Vital D; Alam R; Earls R; Picone C
Prediction of carotid stenosis progression by lipid and hematologic measurements.
Neurology 1989;39(10):1325-31.
1989: Olsen M L; Arnett F C; Rosenbaum D; Grotta J; Warner N B
Sjögren's syndrome and other rheumatic disorders presenting to a neurology service.
Journal of autoimmunity 1989;2(4):477-83.
1989: Johnston J C; Rosenbaum D M; Picone C M; Grotta J C
Apraxia of eyelid opening secondary to right hemisphere infarction.
Annals of neurology 1989;25(6):622-4.
1989: Pettigrew L C; Grotta J C; Rhoades H M; Wu K K
Effect of thromboxane synthase inhibition on eicosanoid levels and blood flow in ischemic rat brain.
Stroke; a journal of cerebral circulation 1989;20(5):627-32.
1988: Pettigrew L C; Grotta J C; Rhoades H M; Reid C; McCandless D W
Regional depletion of adenosine triphosphate, phosphocreatine, and glucose in ischemic hippocampus.
Metabolic brain disease 1988;3(3):185-99.
1988: Grotta J C; Pettigrew L C; Rosenbaum D; Reid C; Rhoades H; McCandless D
Efficacy and mechanism of action of a calcium channel blocker after global cerebral ischemia in rats.
Stroke; a journal of cerebral circulation 1988;19(4):447-54.
1988: Yatsu F M; Hart R G; Mohr J P; Grotta J C
Anticoagulation of embolic strokes of cardiac origin: an update.
Neurology 1988;38(2):314-6.
1986: Grotta J C; Manner C; Pettigrew L C; Yatsu F M
Red blood cell disorders and stroke.
Stroke; a journal of cerebral circulation 1986;17(5):811-7.
1986: Yatsu F M; Grotta J C; Pettigrew L C
Asymptomatic carotid bruit and stenosis.
Seminars in neurology 1986;6(3):262-6.
1986: Grotta J C
Emerging stroke therapies.
Seminars in neurology 1986;6(3):285-92.
1985: Grotta J C; Pettigrew L C; Allen S; Tonnesen A; Yatsu F M; Gray J; Spydell J
Baseline hemodynamic state and response to hemodilution in patients with acute cerebral ischemia.
Stroke; a journal of cerebral circulation 1985;16(5):790-5.
1985: Grotta J C; Lemak N A; Gary H; Fields W S; Vital D
Does platelet antiaggregant therapy lessen the severity of stroke?
Neurology 1985;35(5):632-6.

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