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William Gruber

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Lily Yin Weckx; Eitan Naaman Berezin; Clovis Arns da Cunha; Sonia Maria de Faria; Emilio A Emini; William C Gruber; Scott Patterson; Michael William Pride; Daniel A Scott; Allison Thompson
A phase 3, randomized, double-blind trial comparing the safety and immunogenicity of the 7-valent and 13-valent pneumococcal conjugate vaccines, given with routine pediatric vaccinations, in healthy infants in Brazil.
Eric Mallet; Ahmad Razmpour; Elisabeth Brachet; Philip Fernsten; William C Gruber; France Laudat
Immunogenicity and safety of CRM₁₉₇ conjugated 9-valent pneumococcal and meningococcal C combination vaccine in healthy infants.
Hartmut Lode; A Razmpour; B Schmoele-Thoma; G Siber; T Welte; N Ahlers; S Baker; Olaf Burkhardt; P Fernsten; William C Gruber; Jill Hackell; Stephen Lockhart; Andres De Roux
Dose-ranging study of a single injection of pneumococcal conjugate vaccine (1 ×, 2 ×, or 4 ×) in healthy subjects aged 70 years or older.

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2012: Lily Yin Weckx; Eitan Naaman Berezin; Clovis Arns da Cunha; Sonia Maria de Faria; Emilio A Emini; William C Gruber; Scott Patterson; Michael William Pride; Daniel A Scott; Allison Thompson
A phase 3, randomized, double-blind trial comparing the safety and immunogenicity of the 7-valent and 13-valent pneumococcal conjugate vaccines, given with routine pediatric vaccinations, in healthy infants in Brazil.
Vaccine 2012;30(52):7566-72.
2011: Eric Mallet; Ahmad Razmpour; Elisabeth Brachet; Philip Fernsten; William C Gruber; France Laudat
Immunogenicity and safety of CRM₁₉₇ conjugated 9-valent pneumococcal and meningococcal C combination vaccine in healthy infants.
Vaccine 2011;29(34):5812-9.
2011: Hartmut Lode; A Razmpour; B Schmoele-Thoma; G Siber; T Welte; N Ahlers; S Baker; Olaf Burkhardt; P Fernsten; William C Gruber; Jill Hackell; Stephen Lockhart; Andres De Roux
Dose-ranging study of a single injection of pneumococcal conjugate vaccine (1 ×, 2 ×, or 4 ×) in healthy subjects aged 70 years or older.
Vaccine 2011;29(31):4940-6.
2010: Susanna Esposito; Susan Tansey; Allison Thompson; Ahmad Razmpour; John Liang; Thomas R Jones; Giuseppe Ferrera; Alessandro Maida; Gianni Bona; Caterina Sabatini; Lorenza Pugni; Emilio A Emini; William C Gruber; Daniel A Scott; Nicola Principi
Safety and immunogenicity of a 13-valent pneumococcal conjugate vaccine compared to those of a 7-valent pneumococcal conjugate vaccine given as a three-dose series with routine vaccines in healthy infants and toddlers.
Clinical and vaccine immunology : CVI 2010;17(6):1017-26.
2009: Robert Breiman; W Abdullah Brooks; Doli Goswami; Rosanna Lagos; Charissa Borja-Tabora; Claudio F Lanata; Jaime A Cèspedes Londoño; Lucy Chai See Lum; Ruth Rappaport; Ahmad Razmpour; Robert E Walker; William C Gruber; Bruce D Forrest
A multinational, randomized, placebo-controlled trial to assess the immunogenicity, safety, and tolerability of live attenuated influenza vaccine coadministered with oral poliovirus vaccine in healthy young children.
Vaccine 2009;27(40):5472-9.
2009: Humberto Bracco Neto; Calil K Farhat; Miguel Wenceslao Tregnaghi; Shabir A Madhi; Ahmad Razmpour; Giuseppe Palladino; Margaret G Small; William C Gruber; Bruce D Forrest
Efficacy and safety of 1 and 2 doses of live attenuated influenza vaccine in vaccine-naive children.
The Pediatric infectious disease journal 2009;28(5):365-71.
2008: Timo Vesikari; Aino Karvonen; Helen M Smith; Andrew Dunning; Ahmad Razmpour; Melanie K Saville; William C Gruber; Bruce D Forrest
Safety and tolerability of cold-adapted influenza vaccine, trivalent, in infants younger than 6 months of age.
Pediatrics 2008;121(3):e568-73.
2007: Peter F Wright; Ruth A Karron; Robert B Belshe; Jian R Shi; Valerie B Randolph; Peter L Collins; Alice F O'Shea; William C Gruber; Brian Murphy
The absence of enhanced disease with wild type respiratory syncytial virus infection occurring after receipt of live, attenuated, respiratory syncytial virus vaccines.
Vaccine 2007;25(42):7372-8.
2007: John S Tam; Maria Rosario Z Capeding; Lucy Chai See Lum; Tawee Chotpitayasunondh; Zaifang Jiang; Li-Min Huang; Bee Wah Lee; Yuan Qian; Rudiwilai Samakoses; Somsak Lolekha; K Pillai Rajamohanan; S Noel Narayanan; Chellam Kirubakaran; Ruth Rappaport; Ahmad Razmpour; William C Gruber; Bruce D Forrest
Efficacy and safety of a live attenuated, cold-adapted influenza vaccine, trivalent against culture-confirmed influenza in young children in Asia.
The Pediatric infectious disease journal 2007;26(7):619-28.
2007: Peter F Wright; Anne M Deatly; Ruth A Karron; Robert B Belshe; Jian R Shi; William C Gruber; Yuwei Zhu; Valerie B Randolph
Comparison of results of detection of rhinovirus by PCR and viral culture in human nasal wash specimens from subjects with and without clinical symptoms of respiratory illness.
Journal of clinical microbiology 2007;45(7):2126-9.
2006: Timo Vesikari; Douglas M Fleming; Javier F Aristegui; Andre Vertruyen; Shai Ashkenazi; Ruth Rappaport; Jonathan Skinner; Melanie K Saville; William C Gruber; Bruce D Forrest
Safety, efficacy, and effectiveness of cold-adapted influenza vaccine-trivalent against community-acquired, culture-confirmed influenza in young children attending day care.
Pediatrics 2006;118(6):2298-312.
2006: Shai Ashkenazi; Andre Vertruyen; Javier Arístegui; Susanna Esposito; David Douglas McKeith; Timo Klemola; Jiri Biolek; Joachim Kühr; Tadeusz Bujnowski; Daniel Desgrandchamps; Sheau-Mei Cheng; Jonathan Skinner; William C Gruber; Bruce D Forrest
Superior relative efficacy of live attenuated influenza vaccine compared with inactivated influenza vaccine in young children with recurrent respiratory tract infections.
The Pediatric infectious disease journal 2006;25(10):870-9.
2006: Douglas M Fleming; Pietro Crovari; Ulrich Wahn; Timo Klemola; Yechiel Schlesinger; Alexangros Langussis; Knut Øymar; Maria Luz Garcia; Alain Krygier; Herculano Costa; Ulrich Heininger; Jean-Louis Pregaldien; Sheau-Mei Cheng; Jonathan Skinner; Ahmad Razmpour; Melanie K Saville; William C Gruber; Bruce D Forrest
Comparison of the efficacy and safety of live attenuated cold-adapted influenza vaccine, trivalent, with trivalent inactivated influenza virus vaccine in children and adolescents with asthma.
The Pediatric infectious disease journal 2006;25(10):860-9.
2006: Timo Vesikari; Aino Karvonen; Tiina Korhonen; Kati Edelman; Raija Vainionpää; Aimo A Salmi; Melanie K Saville; Iksung Cho; Ahmad Razmpour; Ruth Rappaport; Robert O'Neill; Alice Georgiu; William C Gruber; Paul M Mendelman; Bruce D Forrest
A randomized, double-blind study of the safety, transmissibility and phenotypic and genotypic stability of cold-adapted influenza virus vaccine.
The Pediatric infectious disease journal 2006;25(7):590-5.
2006: Shabir A Madhi; Clare Cutland; Yuwei Zhu; Jill Hackell; Frances K Newman; Nigel Blackburn; Brian Murphy; Robert B Belshe; Ruth A Karron; Anne M Deatly; William C Gruber; David I Bernstein; Peter F Wright
Transmissibility, infectivity and immunogenicity of a live human parainfluenza type 3 virus vaccine (HPIV3cp45) among susceptible infants and toddlers.
Vaccine 2006;24(13):2432-9.
2006: Peter F Wright; Ruth A Karron; Shabir A Madhi; John J Treanor; James C King; Alice O'Shea; Mine R Ikizler; Yuwei Zhu; Peter L Collins; Clare Cutland; Valerie B Randolph; Anne M Deatly; Jill Hackell; William C Gruber; Brian Murphy
The interferon antagonist NS2 protein of respiratory syncytial virus is an important virulence determinant for humans.
The Journal of infectious diseases 2006;193(4):573-81.
2005: Ruth A Karron; Peter F Wright; Robert B Belshe; Bhagvanji Thumar; Roberta Casey; Frances K Newman; Fernando P Polack; Valerie B Randolph; Anne M Deatly; Jill Hackell; William C Gruber; Brian Murphy; Peter L Collins
Identification of a recombinant live attenuated respiratory syncytial virus vaccine candidate that is highly attenuated in infants.
The Journal of infectious diseases 2005;191(7):1093-104.
2004: Robert B Belshe; Frances K Newman; Edwin L Anderson; Peter F Wright; Ruth A Karron; Sharon J Tollefson; Frederick W Henderson; H Cody Meissner; Shabir A Madhi; Don Roberton; Helen Marshall; Richard Loh; Peter Sly; Brian Murphy; Joanne M Tatem; Valerie B Randolph; Jill Hackell; William C Gruber; Theodore F Tsai
Evaluation of combined live, attenuated respiratory syncytial virus and parainfluenza 3 virus vaccines in infants and young children.
The Journal of infectious diseases 2004;190(12):2096-103.
2004: Paul M Mendelman; Ruth Rappaport; Iksung Cho; Stan Block; William C Gruber; Marilyn J August; Denise M Dawson; Julie M Cordova; George W Kemble; Kutubuddin Mahmood; Giuseppe Palladino; Min-Shi Lee; Ahmad Razmpour; Jeffrey J Stoddard; Bruce D Forrest
Live attenuated influenza vaccine induces cross-reactive antibody responses in children against an a/Fujian/411/2002-like H3N2 antigenic variant strain.
The Pediatric infectious disease journal 2004;23(11):1053-5.
2002: William C Gruber
The role of live influenza vaccines in children.
Vaccine 2002;20 Suppl 2():S66-73.
2002: Peter F Wright; William C Gruber; Melissa Peters; George Reed; Yuwei Zhu; Frances Robinson; Shanita Coleman-Dockery; Barney S Graham
Illness severity, viral shedding, and antibody responses in infants hospitalized with bronchiolitis caused by respiratory syncytial virus.
The Journal of infectious diseases 2002;185(8):1011-8.
2001: Robert B Belshe; William C Gruber
Safety, efficacy and effectiveness of cold-adapted, live, attenuated, trivalent, intranasal influenza vaccine in adults and children.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 2001;356(1416):1947-51.
2000: Robert B Belshe; William C Gruber
Prevention of otitis media in children with live attenuated influenza vaccine given intranasally.
The Pediatric infectious disease journal 2000;19(5 Suppl):S66-71.
2000: Robert B Belshe; William C Gruber; Paul M Mendelman; Hersh Mehta; Kutubuddin Mahmood; Keith S Reisinger; John Treanor; Kenneth M Zangwill; FG Hayden; David I Bernstein; Karen L Kotloff; James C King; Pedro Piedra; S L Block; Lihan Yan; Mark Wolff
Correlates of immune protection induced by live, attenuated, cold-adapted, trivalent, intranasal influenza virus vaccine.
The Journal of infectious diseases 2000;181(3):1133-7.
2000: Robert B Belshe; William C Gruber; Paul M Mendelman; Iksung Cho; Keith S Reisinger; S L Block; Janet Wittes; D Iacuzio; Pedro Piedra; John Treanor; James C King; Karen L Kotloff; David I Bernstein; FG Hayden; Kenneth M Zangwill; Lihan Yan; Mark Wolff
Efficacy of vaccination with live attenuated, cold-adapted, trivalent, intranasal influenza virus vaccine against a variant (A/Sydney) not contained in the vaccine.
The Journal of pediatrics 2000;136(2):168-75.
2000: Richard Malley; Louis Vernacchio; John P DeVincenzo; Octavio Ramilo; Penelope H Dennehy; H Cody Meissner; William C Gruber; Hasan Jafri; P Sanchez; Kristin MacDonald; J B Montana; C M Thompson; Donna M Ambrosino
Enzyme-linked immunosorbent assay to assess respiratory syncytial virus concentration and correlate results with inflammatory mediators in tracheal secretions.
The Pediatric infectious disease journal 2000;19(1):1-7.
1999: Thomas G Boyce; William C Gruber; Shanita Coleman-Dockery; Edith Sannella; George W Reed; M Wolff; Peter F Wright
Mucosal immune response to trivalent live attenuated intranasal influenza vaccine in children.
Vaccine 1999;18(1-2):82-8.
1998: Richard Malley; John P DeVincenzo; Octavio Ramilo; Penelope H Dennehy; H Cody Meissner; William C Gruber; P Sanchez; Hasan Jafri; �James F Balsley; David A Carlin; Steven C Buckingham; Louis Vernacchio; Donna M Ambrosino
Reduction of respiratory syncytial virus (RSV) in tracheal aspirates in intubated infants by use of humanized monoclonal antibody to RSV F protein.
The Journal of infectious diseases 1998;178(6):1555-61.
1998: Robert B Belshe; Paul M Mendelman; John Treanor; James C King; William C Gruber; Pedro Piedra; David I Bernstein; FG Hayden; Karen L Kotloff; Kenneth M Zangwill; D Iacuzio; Mark Wolff
The efficacy of live attenuated, cold-adapted, trivalent, intranasal influenzavirus vaccine in children.
The New England journal of medicine 1998;338(20):1405-12.
1997: WJ Rodriguez; William C Gruber; Jessie R Groothuis; Eric A F Simoes; A J Rosas; M Lepow; Andrew A Kramer; Val G Hemming
Respiratory syncytial virus immune globulin treatment of RSV lower respiratory tract infection in previously healthy children.
Pediatrics 1997;100(6):937-42.
1997: W Paul Glezen; Larry H Taber; Arthur L Frank; William C Gruber; Pedro Piedra
Influenza virus infections in infants.
The Pediatric infectious disease journal 1997;16(11):1065-8.
1997: William C Gruber; Paul M Darden; J G Still; Jacob Lohr; George Reed; Peter F Wright
Evaluation of bivalent live attenuated influenza A vaccines in children 2 months to 3 years of age: safety, immunogenicity and dose-response.
Vaccine 1997;15(12-13):1379-84.
1997: WJ Rodriguez; William C Gruber; Robert C Welliver; Jessie R Groothuis; Eric A F Simoes; H Cody Meissner; Val G Hemming; Caroline Breese Hall; M L Lepow; A J Rosas; C Robertsen; Andrew Kramer
Respiratory syncytial virus (RSV) immune globulin intravenous therapy for RSV lower respiratory tract infection in infants and young children at high risk for severe RSV infections: Respiratory Syncytial Virus Immune Globulin Study Group.
Pediatrics 1997;99(3):454-61.
1997: RG Fisher; William C Gruber; Kathryn M Edwards; George W Reed; Sharon J Tollefson; J M Thompson; Peter F Wright
Twenty years of outpatient respiratory syncytial virus infection: a framework for vaccine efficacy trials.
Pediatrics 1997;99(2):E7.
1997: Kathleen M Neuzil; William C Gruber; Barney S Graham
Vitamin A therapy for respiratory syncytial virus infection.
The Pediatric infectious disease journal 1997;16(1):84-5.
1996: William C Gruber; Robert B Belshe; James C King; John Treanor; Pedro Piedra; Peter F Wright; George W Reed; E Anderson; F Newman
Evaluation of live attenuated influenza vaccines in children 6-18 months of age: safety, immunogenicity, and efficacy. National Institute of Allergy and Infectious Diseases, Vaccine and Treatment Evaluation Program and the Wyeth-Ayerst ca Influenza Vaccine Investigators Group.
The Journal of infectious diseases 1996;173(6):1313-9.
1995: Barney S Graham; Yi-Wei Tang; William C Gruber
Topical immunoprophylaxis of respiratory syncytial virus (RSV)-challenged mice with RSV-specific immune globulin.
The Journal of infectious diseases 1995;171(6):1468-74.
1995: Kathleen M Neuzil; William C Gruber; F Chytil; Mildred T Stahlman; Barney S Graham
Safety and pharmacokinetics of vitamin A therapy for infants with respiratory syncytial virus infections.
Antimicrobial agents and chemotherapy 1995;39(5):1191-3.
1994: Kathleen M Neuzil; William C Gruber; F Chytil; Mildred T Stahlman; B Engelhardt; Barney S Graham
Serum vitamin A levels in respiratory syncytial virus infection.
The Journal of pediatrics 1994;124(3):433-6.
1994: William C Gruber; Preston W Campbell; J M Thompson; George W Reed; B Roberts; Peter F Wright
Comparison of live attenuated and inactivated influenza vaccines in cystic fibrosis patients and their families: results of a 3-year study.
The Journal of infectious diseases 1994;169(2):241-7.
1993: William C Gruber; H P Hinson; K L Holland; J M Thompson; George W Reed; Peter F Wright
Comparative trial of large-particle aerosol and nose drop administration of live attenuated influenza vaccines.
The Journal of infectious diseases 1993;168(5):1282-5.
1993: William C Gruber; D J Russell; C Tibbetts
Fiber gene and genomic origin of human adenovirus type 4.
Virology 1993;196(2):603-11.
1993: Barney S Graham; T H Davis; Yi-Wei Tang; William C Gruber
Immunoprophylaxis and immunotherapy of respiratory syncytial virus-infected mice with respiratory syncytial virus-specific immune serum.
Pediatric research 1993;34(2):167-72.
1993: William C Gruber; K Kirschner; Sharon J Tollefson; Juliette Thompson; George Reed; Kathryn M Edwards; Peter F Wright
Comparison of monovalent and trivalent live attenuated influenza vaccines in young children.
The Journal of infectious diseases 1993;168(1):53-60.
1993: Pedro Piedra; W Paul Glezen; Innocent N Mbawuike; William C Gruber; B D Baxter; F J Boland; R W Byrd; Leland L Fan; J K Lewis; L J Rhodes
Studies on reactogenicity and immunogenicity of attenuated bivalent cold recombinant influenza type A (CRA) and inactivated trivalent influenza virus (TI) vaccines in infants and young children.
Vaccine 1993;11(7):718-24.
1990: Pedro Piedra; J A Kasel; H J Norton; William C Gruber; JA Garcia-Prats; Carol J Baker
Evaluation of an intravenous immunoglobulin preparation for the prevention of viral infection among hospitalized low birth weight infants.
The Pediatric infectious disease journal 1990;9(7):470-5.
1990: William C Gruber; Larry H Taber; W Paul Glezen; R D Clover; T D Abell; R W Demmler; Robert B Couch
Live attenuated and inactivated influenza vaccine in school-age children.
American journal of diseases of children (1960) 1990;144(5):595-600.
1988: William C Gruber; J B Pietsch
Toxic shock syndrome associated with Staphylococcus aureus enterocolitis.
The Pediatric infectious disease journal 1988;7(1):71-2.
1987: M D Yow; N H White; Larry H Taber; Arthur L Frank; William C Gruber; R A May; H J Norton
Acquisition of cytomegalovirus infection from birth to 10 years: a longitudinal serologic study.
The Journal of pediatrics 1987;110(1):37-42.
1985: William C Gruber; Marcia A Rench; JA Garcia-Prats; M S Edwards; Carol J Baker
Single-dose pharmacokinetics of imipenem-cilastatin in neonates.
Antimicrobial agents and chemotherapy 1985;27(4):511-4.