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Ingrid Grummt

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Co-Publications
Name
19
Voit, Renate
9
Längst, Gernot
8
Mayer, Christine
8
Santoro, Raffaella
8
Schnapp, Andreas
7
Hoffmann-Rohrer, Urs
6
Yuan, Xuejun
6
Iben, Sebastian
5
Zhou, Yonggang
5
Seither, P
4
Stunnenberg, Hendrik
4
Zhao, Jian
4
Jansa, P
4
Li, Junwei
3
Mason, SW

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Publications

TOP 3
Hoppe Sven; Bierhoff Holger; Cado Ivana; Weber Andrea; Tiebe Marcel; Grummt Ingrid; Voit Renate
AMP-activated protein kinase adapts rRNA synthesis to cellular energy supply.
Zhou Yonggang; Schmitz Kerstin-Maike; Mayer Christine; Yuan Xuejun; Akhtar Asifa; Grummt Ingrid
Reversible acetylation of the chromatin remodelling complex NoRC is required for non-coding RNA-dependent silencing.
Szymanski Jedrzej; Mayer Christine; Hoffmann-Rohrer Urs; Kalla Claudia; Grummt Ingrid; Weiss Matthias
Dynamic subcellular partitioning of the nucleolar transcription factor TIF-IA under ribotoxic stress.

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All Publications

2009: Hoppe Sven; Bierhoff Holger; Cado Ivana; Weber Andrea; Tiebe Marcel; Grummt Ingrid; Voit Renate
AMP-activated protein kinase adapts rRNA synthesis to cellular energy supply.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(42):17781-6.
2009: Zhou Yonggang; Schmitz Kerstin-Maike; Mayer Christine; Yuan Xuejun; Akhtar Asifa; Grummt Ingrid
Reversible acetylation of the chromatin remodelling complex NoRC is required for non-coding RNA-dependent silencing.
Nature cell biology 2009;11(8):1010-6.
2009: Szymanski Jedrzej; Mayer Christine; Hoffmann-Rohrer Urs; Kalla Claudia; Grummt Ingrid; Weiss Matthias
Dynamic subcellular partitioning of the nucleolar transcription factor TIF-IA under ribotoxic stress.
Biochimica et biophysica acta 2009;1793(7):1191-8.
2009: Schmitz Kerstin-Maike; Schmitt Nina; Hoffmann-Rohrer Urs; Schäfer Andrea; Grummt Ingrid; Mayer Christine
TAF12 recruits Gadd45a and the nucleotide excision repair complex to the promoter of rRNA genes leading to active DNA demethylation.
Molecular cell 2009;33(3):344-53.
2008: Fátyol Károly; Grummt Ingrid
Proteasomal ATPases are associated with rDNA: the ubiquitin proteasome system plays a direct role in RNA polymerase I transcription.
Biochimica et biophysica acta 2008;1779(12):850-9.
2008: Parlato Rosanna; Kreiner Grzegorz; Erdmann Gitta; Rieker Claus; Stotz Stefanie; Savenkova Ella; Berger Stefan; Grummt Ingrid; Schütz Günther
Activation of an endogenous suicide response after perturbation of rRNA synthesis leads to neurodegeneration in mice.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2008;28(48):12759-64.
2008: Mayer Christine; Neubert Melanie; Grummt Ingrid
The structure of NoRC-associated RNA is crucial for targeting the chromatin remodelling complex NoRC to the nucleolus.
EMBO reports 2008;9(8):774-80.
2008: Bierhoff Holger; Dundr Miroslav; Michels Annemieke A; Grummt Ingrid
Phosphorylation by casein kinase 2 facilitates rRNA gene transcription by promoting dissociation of TIF-IA from elongating RNA polymerase I.
Molecular and cellular biology 2008;28(16):4988-98.
2008: Gorski Stanislaw A; Snyder Sara K; John Sam; Grummt Ingrid; Misteli Tom
Modulation of RNA polymerase assembly dynamics in transcriptional regulation.
Molecular cell 2008;30(4):486-97.
2008: Grummt Ingrid; Ladurner Andreas G
A metabolic throttle regulates the epigenetic state of rDNA.
Cell 2008;133(4):577-80.
2008: Ye Jing; Zhao Jian; Hoffmann-Rohrer Urs; Grummt Ingrid
Nuclear myosin I acts in concert with polymeric actin to drive RNA polymerase I transcription.
Genes & development 2008;22(3):322-30.
2008: McStay Brian; Grummt Ingrid
The epigenetics of rRNA genes: from molecular to chromosome biology.
Annual review of cell and developmental biology 2008;24():131-57.
2007: Yuan Xuejun; Feng Weijun; Imhof Axel; Grummt Ingrid; Zhou Yonggang
Activation of RNA polymerase I transcription by cockayne syndrome group B protein and histone methyltransferase G9a.
Molecular cell 2007;27(4):585-95.
2007: Grummt Ingrid
Different epigenetic layers engage in complex crosstalk to define the epigenetic state of mammalian rRNA genes.
Human molecular genetics 2007;16 Spec No 1():R21-7.
2007: Arai Satoko; Miyake Katsuhisa; Voit Renate; Nemoto Shino; Wakeland Edward K; Grummt Ingrid; Miyazaki Toru
Death-effector domain-containing protein DEDD is an inhibitor of mitotic Cdk1/cyclin B1.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(7):2289-94.
2007: Denissov Sergey; van Driel Marc; Voit Renate; Hekkelman Maarten; Hulsen Tim; Hernandez Nouria; Grummt Ingrid; Wehrens Ron; Stunnenberg Hendrik
Identification of novel functional TBP-binding sites and general factor repertoires.
The EMBO journal 2007;26(4):944-54.
2007: Espada Jesús; Ballestar Esteban; Santoro Raffaella; Fraga Mario F; Villar-Garea Ana; Németh Attila; Lopez-Serra Lidia; Ropero Santiago; Aranda Agustin; Orozco Helena; Moreno Vanessa; Juarranz Angeles; Stockert Juan Carlos; Längst Gernot; Grummt Ingrid; Bickmore Wendy; Esteller Manel
Epigenetic disruption of ribosomal RNA genes and nucleolar architecture in DNA methyltransferase 1 (Dnmt1) deficient cells.
Nucleic acids research 2007;35(7):2191-8.
2006: Li Junwei; Längst Gernot; Grummt Ingrid
NoRC-dependent nucleosome positioning silences rRNA genes.
The EMBO journal 2006;25(24):5735-41.
2006: Mayer C; Grummt I
Ribosome biogenesis and cell growth: mTOR coordinates transcription by all three classes of nuclear RNA polymerases.
Oncogene 2006;25(48):6384-91.
2006: Mayer Christine; Schmitz Kerstin-Maike; Li Junwei; Grummt Ingrid; Santoro Raffaella
Intergenic transcripts regulate the epigenetic state of rRNA genes.
Molecular cell 2006;22(3):351-61.
2006: Ford Ethan; Voit Renate; Liszt Gregory; Magin Cornelia; Grummt Ingrid; Guarente Leonard
Mammalian Sir2 homolog SIRT7 is an activator of RNA polymerase I transcription.
Genes & development 2006;20(9):1075-80.
2006: Percipalle Piergiorgio; Fomproix Nathalie; Cavellán Erica; Voit Renate; Reimer Georg; Krüger Tim; Thyberg Johan; Scheer Ulrich; Grummt Ingrid; Farrants Ann-Kristin Ostlund
The chromatin remodelling complex WSTF-SNF2h interacts with nuclear myosin 1 and has a role in RNA polymerase I transcription.
EMBO reports 2006;7(5):525-30.
2006: Grummt Ingrid
Actin and myosin as transcription factors.
Current opinion in genetics & development 2006;16(2):191-6.
2006: Meraner Joachim; Lechner Markus; Loidl Adele; Goralik-Schramel Maria; Voit Renate; Grummt Ingrid; Loidl Peter
Acetylation of UBF changes during the cell cycle and regulates the interaction of UBF with RNA polymerase I.
Nucleic acids research 2006;34(6):1798-806.
2005: Mayer Christine; Grummt Ingrid
Cellular stress and nucleolar function.
Cell cycle (Georgetown, Tex.) 2005;4(8):1036-8.
2005: Zhou Yonggang; Grummt Ingrid
The PHD finger/bromodomain of NoRC interacts with acetylated histone H4K16 and is sufficient for rDNA silencing.
Current biology : CB 2005;15(15):1434-8.
2005: Yuan Xuejun; Zhou Yonggang; Casanova Emilio; Chai Minqiang; Kiss Eva; Gröne Hermann-Josef; Schütz Günter; Grummt Ingrid
Genetic inactivation of the transcription factor TIF-IA leads to nucleolar disruption, cell cycle arrest, and p53-mediated apoptosis.
Molecular cell 2005;19(1):77-87.
2005: Mayer Christine; Bierhoff Holger; Grummt Ingrid
The nucleolus as a stress sensor: JNK2 inactivates the transcription factor TIF-IA and down-regulates rRNA synthesis.
Genes & development 2005;19(8):933-41.
2005: Santoro Raffaella; Grummt Ingrid
Epigenetic mechanism of rRNA gene silencing: temporal order of NoRC-mediated histone modification, chromatin remodeling, and DNA methylation.
Molecular and cellular biology 2005;25(7):2539-46.
2005: Arabi Azadeh; Wu Siqin; Ridderstråle Karin; Bierhoff Holger; Shiue Chiounan; Fatyol Karoly; Fahlén Sara; Hydbring Per; Söderberg Ola; Grummt Ingrid; Larsson Lars-Gunnar; Wright Anthony P H
c-Myc associates with ribosomal DNA and activates RNA polymerase I transcription.
Nature cell biology 2005;7(3):303-10.
2005: Li Junwei; Santoro Raffaella; Koberna Karel; Grummt Ingrid
The chromatin remodeling complex NoRC controls replication timing of rRNA genes.
The EMBO journal 2005;24(1):120-7.
2004: Philimonenko Vlada V; Zhao Jian; Iben Sebastian; Dingová Hana; Kyselá Katarína; Kahle Michal; Zentgraf Hanswalter; Hofmann Wilma A; de Lanerolle Primal; Hozák Pavel; Grummt Ingrid
Nuclear actin and myosin I are required for RNA polymerase I transcription.
Nature cell biology 2004;6(12):1165-72.
2004: Prisco Marco; Maiorana Arianna; Guerzoni Clara; Calin George; Calabretta Bruno; Voit Renate; Grummt Ingrid; Baserga Renato
Role of pescadillo and upstream binding factor in the proliferation and differentiation of murine myeloid cells.
Molecular and cellular biology 2004;24(12):5421-33.
2004: Mayer Christine; Zhao Jian; Yuan Xuejun; Grummt Ingrid
mTOR-dependent activation of the transcription factor TIF-IA links rRNA synthesis to nutrient availability.
Genes & development 2004;18(4):423-34.
2004: Strohner Ralf; Németh Attila; Nightingale Karl P; Grummt Ingrid; Becker Peter B; Längst Gernot
Recruitment of the nucleolar remodeling complex NoRC establishes ribosomal DNA silencing in chromatin.
Molecular and cellular biology 2004;24(4):1791-8.
2004: Németh Attila; Strohner Ralf; Grummt Ingrid; Längst Gernot
The chromatin remodeling complex NoRC and TTF-I cooperate in the regulation of the mammalian rRNA genes in vivo.
Nucleic acids research 2004;32(14):4091-9.
2003: Grummt Ingrid; Pikaard Craig S
Epigenetic silencing of RNA polymerase I transcription.
Nature reviews. Molecular cell biology 2003;4(8):641-9.
2003: Grummt Ingrid
Life on a planet of its own: regulation of RNA polymerase I transcription in the nucleolus.
Genes & development 2003;17(14):1691-702.
2003: Zhao Jian; Yuan Xuejun; Frödin Morten; Grummt Ingrid
ERK-dependent phosphorylation of the transcription initiation factor TIF-IA is required for RNA polymerase I transcription and cell growth.
Molecular cell 2003;11(2):405-13.
2002: Michaelidis Theologos M; Grummt Ingrid
Mechanism of inhibition of RNA polymerase I transcription by DNA-dependent protein kinase.
Biological chemistry 2002;383(11):1683-90.
2002: Dundr Miroslav; Hoffmann-Rohrer Urs; Hu Qiyue; Grummt Ingrid; Rothblum Lawrence I; Phair Robert D; Misteli Tom
A kinetic framework for a mammalian RNA polymerase in vivo.
Science (New York, N.Y.) 2002;298(5598):1623-6.
2002: Yuan Xuejun; Zhao Jian; Zentgraf Hanswalter; Hoffmann-Rohrer Urs; Grummt Ingrid
Multiple interactions between RNA polymerase I, TIF-IA and TAF(I) subunits regulate preinitiation complex assembly at the ribosomal gene promoter.
EMBO reports 2002;3(11):1082-7.
2002: Santoro Raffaella; Li Junwei; Grummt Ingrid
The nucleolar remodeling complex NoRC mediates heterochromatin formation and silencing of ribosomal gene transcription.
Nature genetics 2002;32(3):393-6.
2002: Bradsher John; Auriol Jerome; Proietti de Santis Luca; Iben Sebastian; Vonesch Jean Luc; Grummt Ingrid; Egly Jean Marc
CSB is a component of RNA pol I transcription.
Molecular cell 2002;10(4):819-29.
2002: Zhou Yonggang; Santoro Raffaella; Grummt Ingrid
The chromatin remodeling complex NoRC targets HDAC1 to the ribosomal gene promoter and represses RNA polymerase I transcription.
The EMBO journal 2002;21(17):4632-40.
2002: Dagher Jehan H; Scheer Ulrich; Voit Renate; Grummt Ingrid; Lonzetti Lilian; Raymond Yves; Senécal Jean-Luc
Autoantibodies to NOR 90/hUBF: longterm clinical and serological followup in a patient with limited systemic sclerosis suggests an antigen driven immune response.
The Journal of rheumatology 2002;29(7):1543-7.
2002: Schlosser Andreas; Bodem Jochen; Bossemeyer Dirk; Grummt Ingrid; Lehmann Wolf Dieter
Identification of protein phosphorylation sites by combination of elastase digestion, immobilized metal affinity chromatography, and quadrupole-time of flight tandem mass spectrometry.
Proteomics 2002;2(7):911-8.
2002: Iben Sebastian; Tschochner Herbert; Bier Mirko; Hoogstraten Deborah; Hozák Pavel; Egly Jean Marc; Grummt Ingrid
TFIIH plays an essential role in RNA polymerase I transcription.
Cell 2002;109(3):297-306.
2001: Voit R; Grummt I
Phosphorylation of UBF at serine 388 is required for interaction with RNA polymerase I and activation of rDNA transcription.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(24):13631-6.
2001: Santoro R; Grummt I
Molecular mechanisms mediating methylation-dependent silencing of ribosomal gene transcription.
Molecular cell 2001;8(3):719-25.
2001: Strohner R; Nemeth A; Jansa P; Hofmann-Rohrer U; Santoro R; Längst G; Grummt I
NoRC--a novel member of mammalian ISWI-containing chromatin remodeling machines.
The EMBO journal 2001;20(17):4892-900.
2001: Ciarmatori S; Scott P H; Sutcliffe J E; McLees A; Alzuherri H M; Dannenberg J H; te Riele H; Grummt I; Voit R; White R J
Overlapping functions of the pRb family in the regulation of rRNA synthesis.
Molecular and cellular biology 2001;21(17):5806-14.
2001: Seither P; Iben S; Thiry M; Grummt I
PAF67, a novel protein that is associated with the initiation-competent form of RNA polymerase I.
Biological chemistry 2001;382(8):1163-70.
2001: Muth V; Nadaud S; Grummt I; Voit R
Acetylation of TAF(I)68, a subunit of TIF-IB/SL1, activates RNA polymerase I transcription.
The EMBO journal 2001;20(6):1353-62.
2001: Jansa P; Burek C; Sander E E; Grummt I
The transcript release factor PTRF augments ribosomal gene transcription by facilitating reinitiation of RNA polymerase I.
Nucleic acids research 2001;29(2):423-9.
2000: Bodem J; Dobreva G; Hoffmann-Rohrer U; Iben S; Zentgraf H; Delius H; Vingron M; Grummt I
TIF-IA, the factor mediating growth-dependent control of ribosomal RNA synthesis, is the mammalian homolog of yeast Rrn3p.
EMBO reports 2000;1(2):171-5.
1999: Jansa P; Grummt I
Mechanism of transcription termination: PTRF interacts with the largest subunit of RNA polymerase I and dissociates paused transcription complexes from yeast and mouse.
Molecular & general genetics : MGG 1999;262(3):508-14.
1999: Klein J; Grummt I
Cell cycle-dependent regulation of RNA polymerase I transcription: the nucleolar transcription factor UBF is inactive in mitosis and early G1.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(11):6096-101.
1999: Voit R; Hoffmann M; Grummt I
Phosphorylation by G1-specific cdk-cyclin complexes activates the nucleolar transcription factor UBF.
The EMBO journal 1999;18(7):1891-9.
1999: Budde A; Grummt I
p53 represses ribosomal gene transcription.
Oncogene 1999;18(4):1119-24.
1999: Grummt I
Regulation of mammalian ribosomal gene transcription by RNA polymerase I.
Progress in nucleic acid research and molecular biology 1999;62():109-54.
1998: Heix J; Vente A; Voit R; Budde A; Michaelidis T M; Grummt I
Mitotic silencing of human rRNA synthesis: inactivation of the promoter selectivity factor SL1 by cdc2/cyclin B-mediated phosphorylation.
The EMBO journal 1998;17(24):7373-81.
1998: Kuhn A; Vente A; Dorée M; Grummt I
Mitotic phosphorylation of the TBP-containing factor SL1 represses ribosomal gene transcription.
Journal of molecular biology 1998;284(1):1-5.
1998: Stegh A H; Schickling O; Ehret A; Scaffidi C; Peterhänsel C; Hofmann T G; Grummt I; Krammer P H; Peter M E
DEDD, a novel death effector domain-containing protein, targeted to the nucleolus.
The EMBO journal 1998;17(20):5974-86.
1998: Längst G; Becker P B; Grummt I
TTF-I determines the chromatin architecture of the active rDNA promoter.
The EMBO journal 1998;17(11):3135-45.
1998: Jansa P; Mason S W; Hoffmann-Rohrer U; Grummt I
Cloning and functional characterization of PTRF, a novel protein which induces dissociation of paused ternary transcription complexes.
The EMBO journal 1998;17(10):2855-64.
1998: Seither P; Iben S; Grummt I
Mammalian RNA polymerase I exists as a holoenzyme with associated basal transcription factors.
Journal of molecular biology 1998;275(1):43-53.
1997: Seither P; Zatsepina O; Hoffmann M; Grummt I
Constitutive and strong association of PAF53 with RNA polymerase I.
Chromosoma 1997;106(4):216-25.
1997: Gerber J K; Gögel E; Berger C; Wallisch M; Müller F; Grummt I; Grummt F
Termination of mammalian rDNA replication: polar arrest of replication fork movement by transcription termination factor TTF-I.
Cell 1997;90(3):559-67.
1997: Voit R; Schäfer K; Grummt I
Mechanism of repression of RNA polymerase I transcription by the retinoblastoma protein.
Molecular and cellular biology 1997;17(8):4230-7.
1997: Seither P; Coy J F; Pouska A; Grummt I
Molecular cloning and characterization of the cDNA encoding the largest subunit of mouse RNA polymerase I.
Molecular & general genetics : MGG 1997;255(2):180-6.
1997: Mason S W; Wallisch M; Grummt I
RNA polymerase I transcription termination: similar mechanisms are employed by yeast and mammals.
Journal of molecular biology 1997;268(2):229-34.
1997: Falciola L; Spada F; Calogero S; Langst G; Voit R; Grummt I; Bianchi M E
High mobility group 1 protein is not stably associated with the chromosomes of somatic cells.
The Journal of cell biology 1997;137(1):19-26.
1997: Sander E E; Grummt I
Oligomerization of the transcription termination factor TTF-I: implications for the structural organization of ribosomal transcription units.
Nucleic acids research 1997;25(6):1142-7.
1997: Heix J; Zomerdijk J C; Ravanpay A; Tjian R; Grummt I
Cloning of murine RNA polymerase I-specific TAF factors: conserved interactions between the subunits of the species-specific transcription initiation factor TIF-IB/SL1.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(5):1733-8.
1997: Längst G; Blank T A; Becker P B; Grummt I
RNA polymerase I transcription on nucleosomal templates: the transcription termination factor TTF-I induces chromatin remodeling and relieves transcriptional repression.
The EMBO journal 1997;16(4):760-8.
1997: Längst G; Schätz T; Langowski J; Grummt I
Structural analysis of mouse rDNA: coincidence between nuclease hypersensitive sites, DNA curvature and regulatory elements in the intergenic spacer.
Nucleic acids research 1997;25(3):511-7.
1997: Mason S W; Sander E E; Grummt I
Identification of a transcript release activity acting on ternary transcription complexes containing murine RNA polymerase I.
The EMBO journal 1997;16(1):163-72.
1996: Seither P; Grummt I
Molecular cloning of RPA2, the gene encoding the second largest subunit of mouse RNA polymerase I.
Genomics 1996;37(1):135-9.
1996: Sander E E; Mason S W; Munz C; Grummt I
The amino-terminal domain of the transcription termination factor TTF-I causes protein oligomerization and inhibition of DNA binding.
Nucleic acids research 1996;24(19):3677-84.
1996: Schnapp G; Graveley B R; Grummt I
TFIIS binds to mouse RNA polymerase I and stimulates transcript elongation and hydrolytic cleavage of nascent rRNA.
Molecular & general genetics : MGG 1996;252(4):412-9.
1996: Gögel E; Längst G; Grummt I; Kunkel E; Grummt F
Mapping of replication initiation sites in the mouse ribosomal gene cluster.
Chromosoma 1996;104(7):511-8.
1996: Eberhard D; Grummt I
Species specificity of ribosomal gene transcription: a factor associated with human RNA polymerase I prevents transcription of mouse rDNA.
DNA and cell biology 1996;15(2):167-73.
1996: Schnapp A; Grummt I
Purification, assay, and properties of RNA polymerase I and class I-specific transcription factors in mouse.
Methods in enzymology 1996;273():233-48.
1995: Heix J; Grummt I
Species specificity of transcription by RNA polymerase I.
Current opinion in genetics & development 1995;5(5):652-6.
1995: Voit R; Kuhn A; Sander E E; Grummt I
Activation of mammalian ribosomal gene transcription requires phosphorylation of the nucleolar transcription factor UBF.
Nucleic acids research 1995;23(14):2593-9.
1995: Evers R; Grummt I
Molecular coevolution of mammalian ribosomal gene terminator sequences and the transcription termination factor TTF-I.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(13):5827-31.
1995: Evers R; Smid A; Rudloff U; Lottspeich F; Grummt I
Different domains of the murine RNA polymerase I-specific termination factor mTTF-I serve distinct functions in transcription termination.
The EMBO journal 1995;14(6):1248-56.
1995: Kuhn A; Gottlieb T M; Jackson S P; Grummt I
DNA-dependent protein kinase: a potent inhibitor of transcription by RNA polymerase I.
Genes & development 1995;9(2):193-203.
1994: Rudloff U; Stunnenberg H G; Keaveney M; Grummt I
Yeast TBP can replace its human homologue in the RNA polymerase I-specific multisubunit factor SL1.
Journal of molecular biology 1994;243(5):840-5.
1994: Schnapp G; Schnapp A; Rosenbauer H; Grummt I
TIF-IC, a factor involved in both transcription initiation and elongation of RNA polymerase I.
The EMBO journal 1994;13(17):4028-35.
1994: Rudloff U; Eberhard D; Grummt I
The conserved core domain of the human TATA binding protein is sufficient to assemble the multisubunit RNA polymerase I-specific transcription factor SL1.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(17):8229-33.
1994: Rudloff U; Eberhard D; Tora L; Stunnenberg H; Grummt I
TBP-associated factors interact with DNA and govern species specificity of RNA polymerase I transcription.
The EMBO journal 1994;13(11):2611-6.
1994: Lescure A; Lutz Y; Eberhard D; Jacq X; Krol A; Grummt I; Davidson I; Chambon P; Tora L
The N-terminal domain of the human TATA-binding protein plays a role in transcription from TATA-containing RNA polymerase II and III promoters.
The EMBO journal 1994;13(5):1166-75.
1994: Kuhn A; Voit R; Stefanovsky V; Evers R; Bianchi M; Grummt I
Functional differences between the two splice variants of the nucleolar transcription factor UBF: the second HMG box determines specificity of DNA binding and transcriptional activity.
The EMBO journal 1994;13(2):416-24.
1994: Schnapp G; Santori F; Carles C; Riva M; Grummt I
The HMG box-containing nucleolar transcription factor UBF interacts with a specific subunit of RNA polymerase I.
The EMBO journal 1994;13(1):190-9.
1993: Schnapp A; Schnapp G; Erny B; Grummt I
Function of the growth-regulated transcription initiation factor TIF-IA in initiation complex formation at the murine ribosomal gene promoter.
Molecular and cellular biology 1993;13(11):6723-32.
1993: Zatsepina O V; Voit R; Grummt I; Spring H; Semenov M V; Trendelenburg M F
The RNA polymerase I-specific transcription initiation factor UBF is associated with transcriptionally active and inactive ribosomal genes.
Chromosoma 1993;102(9):599-611.
1993: Eberhard D; Tora L; Egly J M; Grummt I
A TBP-containing multiprotein complex (TIF-IB) mediates transcription specificity of murine RNA polymerase I.
Nucleic acids research 1993;21(18):4180-6.
1993: Kuhn A; Stefanovsky V; Grummt I
The nucleolar transcription activator UBF relieves Ku antigen-mediated repression of mouse ribosomal gene transcription.
Nucleic acids research 1993;21(9):2057-63.
1992: Smid A; Finsterer M; Grummt I
Limited proteolysis unmasks specific DNA-binding of the murine RNA polymerase I-specific transcription termination factor TTFI.
Journal of molecular biology 1992;227(3):635-47.
1992: Kuhn A; Grummt I
Dual role of the nucleolar transcription factor UBF: trans-activator and antirepressor.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(16):7340-4.
1992: Voit R; Schnapp A; Kuhn A; Rosenbauer H; Hirschmann P; Stunnenberg H G; Grummt I
The nucleolar transcription factor mUBF is phosphorylated by casein kinase II in the C-terminal hyperacidic tail which is essential for transactivation.
The EMBO journal 1992;11(6):2211-8.
1991: Schnapp A; Grummt I
Transcription complex formation at the mouse rDNA promoter involves the stepwise association of four transcription factors and RNA polymerase I.
The Journal of biological chemistry 1991;266(36):24588-95.
1991: Heilgenthal G; Grummt I
Isolation of multiple protein factors involved in ribosomal DNA transcription.
Journal of chromatography 1991;587(1):25-32.
1991: Schnapp A; Rosenbauer H; Grummt I
Trans-acting factors involved in species-specificity and control of mouse ribosomal gene transcription.
Molecular and cellular biochemistry 1991;104(1-2):137-47.
1990: Kuhn A; Deppert U; Grummt I
A 140-base-pair repetitive sequence element in the mouse rRNA gene spacer enhances transcription by RNA polymerase I in a cell-free system.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(19):7527-31.
1990: Schnapp A; Pfleiderer C; Rosenbauer H; Grummt I
A growth-dependent transcription initiation factor (TIF-IA) interacting with RNA polymerase I regulates mouse ribosomal RNA synthesis.
The EMBO journal 1990;9(9):2857-63.
1990: Pfleiderer C; Smid A; Bartsch I; Grummt I
An undecamer DNA sequence directs termination of human ribosomal gene transcription.
Nucleic acids research 1990;18(16):4727-36.
1990: Kuhn A; Bartsch I; Grummt I
Specific interaction of the murine transcription termination factor TTF I with class-I RNA polymerases.
Nature 1990;344(6266):559-62.
1990: Schnapp A; Clos J; Hädelt W; Schreck R; Cvekl A; Grummt I
Isolation and functional characterization of TIF-IB, a factor that confers promoter specificity to mouse RNA polymerase I.
Nucleic acids research 1990;18(6):1385-93.
1989: Schreck R; Carey M F; Grummt I
Transcriptional enhancement by upstream activators is brought about by different molecular mechanisms for class I and II RNA polymerase genes.
The EMBO journal 1989;8(10):3011-7.
1989: Kuhn A; Grummt I
3'-end formation of mouse pre-rRNA involves both transcription termination and a specific processing reaction.
Genes & development 1989;3(2):224-31.
1988: Bartsch I; Schoneberg C; Grummt I
Purification and characterization of TTFI, a factor that mediates termination of mouse ribosomal DNA transcription.
Molecular and cellular biology 1988;8(9):3891-7.
1988: Kuhn A; Normann A; Bartsch I; Grummt I
The mouse ribosomal gene terminator consists of three functionally separable sequence elements.
The EMBO journal 1988;7(5):1497-502.
1987: Kuhn A; Grummt I
A novel promoter in the mouse rDNA spacer is active in vivo and in vitro.
The EMBO journal 1987;6(11):3487-92.
1987: Bartsch I; Schoneberg C; Grummt I
Evolutionary changes of sequences and factors that direct transcription termination of human and mouse ribsomal genes.
Molecular and cellular biology 1987;7(7):2521-9.
1986: Grummt I; Kuhn A; Bartsch I; Rosenbauer H
A transcription terminator located upstream of the mouse rDNA initiation site affects rRNA synthesis.
Cell 1986;47(6):901-11.
1986: Clos J; Normann A; Ohrlein A; Grummt I
The core promoter of mouse rDNA consists of two functionally distinct domains.
Nucleic acids research 1986;14(19):7581-95.
1986: Grummt I; Rosenbauer H; Niedermeyer I; Maier U; Ohrlein A
A repeated 18 bp sequence motif in the mouse rDNA spacer mediates binding of a nuclear factor and transcription termination.
Cell 1986;45(6):837-46.
1985: Grummt I; Maier U; Ohrlein A; Hassouna N; Bachellerie J P
Transcription of mouse rDNA terminates downstream of the 3' end of 28S RNA and involves interaction of factors with repeated sequences in the 3' spacer.
Cell 1985;43(3 Pt 2):801-10.
1984: Skinner J A; Ohrlein A; Grummt I
In vitro mutagenesis and transcriptional analysis of a mouse ribosomal promoter element.
Proceedings of the National Academy of Sciences of the United States of America 1984;81(7):2137-41.

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