FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

J Grünberg

Research Profile

Chemicals & Drugs

Disorders

Alzheimer's Disease

Physiology

Genes & Molecular Sequences

Amino Acid Sequences

Concepts & Ideas

Molecular Sequence Data

Anatomy

Living Beings

Mouse

Phenomena

Co-author Network

Publications

TOP 3
U Leimer; K Lun; H Romig; Jochen Walter; J Grünberg; M Brand; Christian Haass
Zebrafish (Danio rerio) presenilin promotes aberrant amyloid beta-peptide production and requires a critical aspartate residue for its function in amyloidogenesis.
A Diehlmann; N Ida; Sascha Weggen; J Grünberg; Christian Haass; Colin L Masters; Thomas A Bayer; Konrad Beyreuther
Analysis of presenilin 1 and presenilin 2 expression and processing by newly developed monoclonal antibodies.
Jochen Walter; A Schindzielorz; J Grünberg; Christian Haass
Phosphorylation of presenilin-2 regulates its cleavage by caspases and retards progression of apoptosis.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of J Grünberg (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

1999: U Leimer; K Lun; H Romig; Jochen Walter; J Grünberg; M Brand; Christian Haass
Zebrafish (Danio rerio) presenilin promotes aberrant amyloid beta-peptide production and requires a critical aspartate residue for its function in amyloidogenesis.
Biochemistry 1999;38(41):13602-9.
1999: A Diehlmann; N Ida; Sascha Weggen; J Grünberg; Christian Haass; Colin L Masters; Thomas A Bayer; Konrad Beyreuther
Analysis of presenilin 1 and presenilin 2 expression and processing by newly developed monoclonal antibodies.
Journal of neuroscience research 1999;56(4):405-19.
1999: Jochen Walter; A Schindzielorz; J Grünberg; Christian Haass
Phosphorylation of presenilin-2 regulates its cleavage by caspases and retards progression of apoptosis.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(4):1391-6.
1998: J Grünberg; Jochen Walter; Christopher B Eckman; Anja Capell; A Schindzielorz; Steven G Younkin; N Mehta; John Hardy; Christian Haass
Truncated presenilin 2 derived from differentially spliced mRNA does not affect the ratio of amyloid beta-peptide 1-42/1-40.
Neuroreport 1998;9(14):3293-9.
1998: Fumitaka Oyama; N Sawamura; K Kobayashi; Maho Morishima-Kawashima; T Kuramochi; Mie Ito; Taisuke Tomita; Kei Maruyama; Takaomi C Saido; Takeshi Iwatsubo; Anja Capell; Jochen Walter; J Grünberg; Yoshito Ueyama; Christian Haass; Yasuo Ihara
Mutant presenilin 2 transgenic mouse: effect on an age-dependent increase of amyloid beta-protein 42 in the brain.
Journal of neurochemistry 1998;71(1):313-22.
1998: Manfred Brockhaus; J Grünberg; S Röhrig; Hansruedi Loetscher; N Wittenburg; Ralf Baumeister; Helmut Jacobsen; Christian Haass
Caspase-mediated cleavage is not required for the activity of presenilins in amyloidogenesis and NOTCH signaling.
Neuroreport 1998;9(7):1481-6.
1998: Jochen Walter; J Grünberg; A Schindzielorz; Christian Haass
Proteolytic fragments of the Alzheimer's disease associated presenilins-1 and -2 are phosphorylated in vivo by distinct cellular mechanisms.
Biochemistry 1998;37(17):5961-7.
1998: Anja Capell; J Grünberg; B Pesold; A Diehlmann; Martin Citron; Ralph A. Nixon; Konrad Beyreuther; Dennis J Selkoe; Christian Haass
The proteolytic fragments of the Alzheimer's disease-associated presenilin-1 form heterodimers and occur as a 100-150-kDa molecular mass complex.
The Journal of biological chemistry 1998;273(6):3205-11.
1998: Christian Haass; J Grünberg; Anja Capell; Christine Wild-Bode; U Leimer; Jochen Walter; T Yamazaki; I Ihara; I Zweckbronner; C Jakubek; Ralf Baumeister
Proteolytic processing of Alzheimer's disease associated proteins.
Journal of neural transmission. Supplementum 1998;53():159-67.
1997: Anja Capell; Rainer Saffrich; JC Olivo; Liane Meyn; Jochen Walter; J Grünberg; Paul Mathews; Ralph A. Nixon; Carlos G Dotti; Christian Haass
Cellular expression and proteolytic processing of presenilin proteins is developmentally regulated during neuronal differentiation.
Journal of neurochemistry 1997;69(6):2432-40.
1997: Hansruedi Loetscher; Ulrich Deuschle; Manfred Brockhaus; D Reinhardt; Peter Nelboeck; Jan Mous; J Grünberg; Christian Haass; Helmut Jacobsen
Presenilins are processed by caspase-type proteases.
The Journal of biological chemistry 1997;272(33):20655-9.
1997: Jochen Walter; J Grünberg; Anja Capell; B Pesold; A Schindzielorz; Martin Citron; Klaus Mendla; Peter St George-Hyslop; Gerd Multhaup; Dennis J Selkoe; Christian Haass
Proteolytic processing of the Alzheimer disease-associated presenilin-1 generates an in vivo substrate for protein kinase C.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(10):5349-54.
1997: Ralf Baumeister; U Leimer; I Zweckbronner; C Jakubek; J Grünberg; Christian Haass
Human presenilin-1, but not familial Alzheimer's disease (FAD) mutants, facilitate Caenorhabditis elegans Notch signalling independently of proteolytic processing.
Genes and function 1997;1(2):149-59.
1997: Taisuke Tomita; Kei Maruyama; Takaomi C Saido; H Kume; K Shinozaki; S Tokuhiro; Anja Capell; Jochen Walter; J Grünberg; Christian Haass; Takeshi Iwatsubo; Kunihiko Obata
The presenilin 2 mutation (N141I) linked to familial Alzheimer disease (Volga German families) increases the secretion of amyloid beta protein ending at the 42nd (or 43rd) residue.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(5):2025-30.
1996: Jochen Walter; Anja Capell; J Grünberg; B Pesold; A Schindzielorz; R Prior; Marcia B Podlisny; Paul E Fraser; Peter St George-Hyslop; Dennis J Selkoe; Christian Haass
The Alzheimer's disease-associated presenilins are differentially phosphorylated proteins located predominantly within the endoplasmic reticulum.
Molecular medicine (Cambridge, Mass.) 1996;2(6):673-91.