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Michael Grunstein

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Chemicals & Drugs

Living Beings

Saccharomyces cerevisiae

Physiology

Phenomena

Acetylation

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Molecular Sequence Data

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TOP 3
Sperling Adam S; Grunstein Michael
Histone H3 N-terminus regulates higher order structure of yeast heterochromatin.
Chin Mark H; Mason Mike J; Xie Wei; Volinia Stefano; Singer Mike; Peterson Cory; Ambartsumyan Gayane; Aimiuwu Otaren; Richter Laura; Zhang Jin; Khvorostov Ivan; Ott Vanessa; Grunstein Michael; Lavon Neta; Benvenisty Nissim; Croce Carlo M; Clark Amander T; Baxter Tim; Pyle April D; Teitell Mike A; Pelegrini Matteo; Plath Kathrin; Lowry William E
Induced pluripotent stem cells and embryonic stem cells are distinguished by gene expression signatures.
Xie Wei; Song Chunying; Young Nicolas L; Sperling Adam S; Xu Feng; Sridharan Rupa; Conway Anne E; Garcia Benjamin A; Plath Kathrin; Clark Amander T; Grunstein Michael
Histone h3 lysine 56 acetylation is linked to the core transcriptional network in human embryonic stem cells.

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All Publications

2009: Sperling Adam S; Grunstein Michael
Histone H3 N-terminus regulates higher order structure of yeast heterochromatin.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(32):13153-9.
2009: Chin Mark H; Mason Mike J; Xie Wei; Volinia Stefano; Singer Mike; Peterson Cory; Ambartsumyan Gayane; Aimiuwu Otaren; Richter Laura; Zhang Jin; Khvorostov Ivan; Ott Vanessa; Grunstein Michael; Lavon Neta; Benvenisty Nissim; Croce Carlo M; Clark Amander T; Baxter Tim; Pyle April D; Teitell Mike A; Pelegrini Matteo; Plath Kathrin; Lowry William E
Induced pluripotent stem cells and embryonic stem cells are distinguished by gene expression signatures.
Cell stem cell 2009;5(1):111-23.
2009: Xie Wei; Song Chunying; Young Nicolas L; Sperling Adam S; Xu Feng; Sridharan Rupa; Conway Anne E; Garcia Benjamin A; Plath Kathrin; Clark Amander T; Grunstein Michael
Histone h3 lysine 56 acetylation is linked to the core transcriptional network in human embryonic stem cells.
Molecular cell 2009;33(4):417-27.
2008: Houseley Jonathan; Rubbi Liudmilla; Grunstein Michael; Tollervey David; Vogelauer Maria
A ncRNA modulates histone modification and mRNA induction in the yeast GAL gene cluster.
Molecular cell 2008;32(5):685-95.
2008: Kaplan Tommy; Liu Chih Long; Erkmann Judith A; Holik John; Grunstein Michael; Kaufman Paul D; Friedman Nir; Rando Oliver J
Cell cycle- and chaperone-mediated regulation of H3K56ac incorporation in yeast.
PLoS genetics 2008;4(11):e1000270.
2008: Horwitz Gregory A; Zhang Kangling; McBrian Matthew A; Grunstein Michael; Kurdistani Siavash K; Berk Arnold J
Adenovirus small e1a alters global patterns of histone modification.
Science (New York, N.Y.) 2008;321(5892):1084-5.
2007: Xu Feng; Zhang Qiongyi; Zhang Kangling; Xie Wei; Grunstein Michael
Sir2 deacetylates histone H3 lysine 56 to regulate telomeric heterochromatin structure in yeast.
Molecular cell 2007;27(6):890-900.
2007: Durand-Dubief Mickaël; Sinha Indranil; Fagerström-Billai Fredrik; Bonilla Carolina; Wright Anthony; Grunstein Michael; Ekwall Karl
Specific functions for the fission yeast Sirtuins Hst2 and Hst4 in gene regulation and retrotransposon silencing.
The EMBO journal 2007;26(10):2477-88.
2007: Shahbazian Mona D; Grunstein Michael
Functions of site-specific histone acetylation and deacetylation.
Annual review of biochemistry 2007;76():75-100.
2006: Millar Catherine B; Grunstein Michael
Genome-wide patterns of histone modifications in yeast.
Nature reviews. Molecular cell biology 2006;7(9):657-66.
2006: Millar Catherine B; Xu Feng; Zhang Kangling; Grunstein Michael
Acetylation of H2AZ Lys 14 is associated with genome-wide gene activity in yeast.
Genes & development 2006;20(6):711-22.
2005: Keogh Michael-Christopher; Kurdistani Siavash K; Morris Stephanie A; Ahn Seong Hoon; Podolny Vladimir; Collins Sean R; Schuldiner Maya; Chin Kayu; Punna Thanuja; Thompson Natalie J; Boone Charles; Emili Andrew; Weissman Jonathan S; Hughes Timothy R; Strahl Brian D; Grunstein Michael; Greenblatt Jack F; Buratowski Stephen; Krogan Nevan J
Cotranscriptional set2 methylation of histone H3 lysine 36 recruits a repressive Rpd3 complex.
Cell 2005;123(4):593-605.
2005: Wirén Marianna; Silverstein Rebecca A; Sinha Indranil; Walfridsson Julian; Lee Hang-Mao; Laurenson Patricia; Pillus Lorraine; Robyr Daniel; Grunstein Michael; Ekwall Karl
Genomewide analysis of nucleosome density histone acetylation and HDAC function in fission yeast.
The EMBO journal 2005;24(16):2906-18.
2005: Shahbazian Mona D; Zhang Kangling; Grunstein Michael
Histone H2B ubiquitylation controls processive methylation but not monomethylation by Dot1 and Set1.
Molecular cell 2005;19(2):271-7.
2005: Seligson David B; Horvath Steve; Shi Tao; Yu Hong; Tze Sheila; Grunstein Michael; Kurdistani Siavash K
Global histone modification patterns predict risk of prostate cancer recurrence.
Nature 2005;435(7046):1262-6.
2005: Xu Feng; Zhang Kangling; Grunstein Michael
Acetylation in histone H3 globular domain regulates gene expression in yeast.
Cell 2005;121(3):375-85.
2004: Kurdistani Siavash K; Tavazoie Saeed; Grunstein Michael
Mapping global histone acetylation patterns to gene expression.
Cell 2004;117(6):721-33.
2004: Millar C B; Kurdistani S K; Grunstein M
Acetylation of yeast histone H4 lysine 16: a switch for protein interactions in heterochromatin and euchromatin.
Cold Spring Harbor symposia on quantitative biology 2004;69():193-200.
2004: Robyr Daniel; Kurdistani Siavash K; Grunstein Michael
Analysis of genome-wide histone acetylation state and enzyme binding using DNA microarrays.
Methods in enzymology 2004;376():289-304.
2003: Mellone Barbara G; Ball Leslie; Suka Noriyuki; Grunstein Michael R; Partridge Janet F; Allshire Robin C
Centromere silencing and function in fission yeast is governed by the amino terminus of histone H3.
Current biology : CB 2003;13(20):1748-57.
2003: Kurdistani Siavash K; Grunstein Michael
In vivo protein-protein and protein-DNA crosslinking for genomewide binding microarray.
Methods (San Diego, Calif.) 2003;31(1):90-5.
2003: Robyr Daniel; Grunstein Michael
Genomewide histone acetylation microarrays.
Methods (San Diego, Calif.) 2003;31(1):83-9.
2003: Kurdistani Siavash K; Grunstein Michael
Histone acetylation and deacetylation in yeast.
Nature reviews. Molecular cell biology 2003;4(4):276-84.
2002: Vogelauer Maria; Rubbi Liudmilla; Lucas Isabelle; Brewer Bonita J; Grunstein Michael
Histone acetylation regulates the time of replication origin firing.
Molecular cell 2002;10(5):1223-33.
2002: Wang Amy; Kurdistani Siavash K; Grunstein Michael
Requirement of Hos2 histone deacetylase for gene activity in yeast.
Science (New York, N.Y.) 2002;298(5597):1412-4.
2002: Suka Noriyuki; Luo Kunheng; Grunstein Michael
Sir2p and Sas2p opposingly regulate acetylation of yeast histone H4 lysine16 and spreading of heterochromatin.
Nature genetics 2002;32(3):378-83.
2002: Kristjuhan Arnold; Walker Jane; Suka Noriyuki; Grunstein Michael; Roberts Douglas; Cairns Bradley R; Svejstrup Jesper Q
Transcriptional inhibition of genes with severe histone h3 hypoacetylation in the coding region.
Molecular cell 2002;10(4):925-33.
2002: Kurdistani Siavash K; Robyr Daniel; Tavazoie Saeed; Grunstein Michael
Genome-wide binding map of the histone deacetylase Rpd3 in yeast.
Nature genetics 2002;31(3):248-54.
2002: Luo Kunheng; Vega-Palas Miguel A; Grunstein Michael
Rap1-Sir4 binding independent of other Sir, yKu, or histone interactions initiates the assembly of telomeric heterochromatin in yeast.
Genes & development 2002;16(12):1528-39.
2002: Robyr Daniel; Suka Yuko; Xenarios Ioannis; Kurdistani Siavash K; Wang Amy; Suka Noriyuki; Grunstein Michael
Microarray deacetylation maps determine genome-wide functions for yeast histone deacetylases.
Cell 2002;109(4):437-46.
2002: Verdone Loredana; Wu Jiansheng; van Riper Kristen; Kacherovsky Nataly; Vogelauer Maria; Young Elton T; Grunstein Michael; Di Mauro Ernesto; Caserta Micaela
Hyperacetylation of chromatin at the ADH2 promoter allows Adr1 to bind in repressed conditions.
The EMBO journal 2002;21(5):1101-11.
2002: Carmen Andrew A; Milne Lisa; Grunstein Michael
Acetylation of the yeast histone H4 N terminus regulates its binding to heterochromatin protein SIR3.
The Journal of biological chemistry 2002;277(7):4778-81.
2001: Suka N; Suka Y; Carmen A A; Wu J; Grunstein M
Highly specific antibodies determine histone acetylation site usage in yeast heterochromatin and euchromatin.
Molecular cell 2001;8(2):473-9.
2001: Wu J; Carmen A A; Kobayashi R; Suka N; Grunstein M
HDA2 and HDA3 are related proteins that interact with and are essential for the activity of the yeast histone deacetylase HDA1.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(8):4391-6.
2001: Wu J; Suka N; Carlson M; Grunstein M
TUP1 utilizes histone H3/H2B-specific HDA1 deacetylase to repress gene activity in yeast.
Molecular cell 2001;7(1):117-26.
2000: Wu J; Grunstein M
25 years after the nucleosome model: chromatin modifications.
Trends in biochemical sciences 2000;25(12):619-23.
2000: Vogelauer M; Wu J; Suka N; Grunstein M
Global histone acetylation and deacetylation in yeast.
Nature 2000;408(6811):495-8.
1999: Carmen A A; Griffin P R; Calaycay J R; Rundlett S E; Suka Y; Grunstein M
Yeast HOS3 forms a novel trichostatin A-insensitive homodimer with intrinsic histone deacetylase activity.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(22):12356-61.
1999: Martin S G; Laroche T; Suka N; Grunstein M; Gasser S M
Relocalization of telomeric Ku and SIR proteins in response to DNA strand breaks in yeast.
Cell 1999;97(5):621-33.
1999: Hecht A; Strahl-Bolsinger S; Grunstein M
Mapping DNA interaction sites of chromosomal proteins. Crosslinking studies in yeast.
Methods in molecular biology (Clifton, N.J.) 1999;119():469-79.
1999: Hecht A; Grunstein M
Mapping DNA interaction sites of chromosomal proteins using immunoprecipitation and polymerase chain reaction.
Methods in enzymology 1999;304():399-414.
1998: Ma X J; Wu J; Altheim B A; Schultz M C; Grunstein M
Deposition-related sites K5/K12 in histone H4 are not required for nucleosome deposition in yeast.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(12):6693-8.
1998: Grunstein M
Yeast heterochromatin: regulation of its assembly and inheritance by histones.
Cell 1998;93(3):325-8.
1998: Rundlett S E; Carmen A A; Suka N; Turner B M; Grunstein M
Transcriptional repression by UME6 involves deacetylation of lysine 5 of histone H4 by RPD3.
Nature 1998;392(6678):831-5.
1998: Suka N; Carmen A A; Rundlett S E; Grunstein M
The regulation of gene activity by histones and the histone deacetylase RPD3.
Cold Spring Harbor symposia on quantitative biology 1998;63():391-9.
1997: Grunstein M
Histone acetylation in chromatin structure and transcription.
Nature 1997;389(6649):349-52.
1997: Gotta M; Strahl-Bolsinger S; Renauld H; Laroche T; Kennedy B K; Grunstein M; Gasser S M
Localization of Sir2p: the nucleolus as a compartment for silent information regulators.
The EMBO journal 1997;16(11):3243-55.
1997: Grunstein M
Molecular model for telomeric heterochromatin in yeast.
Current opinion in cell biology 1997;9(3):383-7.
1997: Strahl-Bolsinger S; Hecht A; Luo K; Grunstein M
SIR2 and SIR4 interactions differ in core and extended telomeric heterochromatin in yeast.
Genes & development 1997;11(1):83-93.
1996: Rundlett S E; Carmen A A; Kobayashi R; Bavykin S; Turner B M; Grunstein M
HDA1 and RPD3 are members of distinct yeast histone deacetylase complexes that regulate silencing and transcription.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(25):14503-8.
1996: Hecht A; Strahl-Bolsinger S; Grunstein M
Spreading of transcriptional repressor SIR3 from telomeric heterochromatin.
Nature 1996;383(6595):92-6.
1996: Lenfant F; Mann R K; Thomsen B; Ling X; Grunstein M
All four core histone N-termini contain sequences required for the repression of basal transcription in yeast.
The EMBO journal 1996;15(15):3974-85.
1996: Carmen A A; Rundlett S E; Grunstein M
HDA1 and HDA3 are components of a yeast histone deacetylase (HDA) complex.
The Journal of biological chemistry 1996;271(26):15837-44.
1996: Ma X J; Lu Q; Grunstein M
A search for proteins that interact genetically with histone H3 and H4 amino termini uncovers novel regulators of the Swe1 kinase in Saccharomyces cerevisiae.
Genes & development 1996;10(11):1327-40.
1996: Ling X; Harkness T A; Schultz M C; Fisher-Adams G; Grunstein M
Yeast histone H3 and H4 amino termini are important for nucleosome assembly in vivo and in vitro: redundant and position-independent functions in assembly but not in gene regulation.
Genes & development 1996;10(6):686-99.
1995: Wan J S; Mann R K; Grunstein M
Yeast histone H3 and H4 N termini function through different GAL1 regulatory elements to repress and activate transcription.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(12):5664-8.
1995: Fisher-Adams G; Grunstein M
Yeast histone H4 and H3 N-termini have different effects on the chromatin structure of the GAL1 promoter.
The EMBO journal 1995;14(7):1468-77.
1995: Hecht A; Laroche T; Strahl-Bolsinger S; Gasser S M; Grunstein M
Histone H3 and H4 N-termini interact with SIR3 and SIR4 proteins: a molecular model for the formation of heterochromatin in yeast.
Cell 1995;80(4):583-92.
1995: Grunstein M; Hecht A; Fisher-Adams G; Wan J; Mann R K; Strahl-Bolsinger S; Laroche T; Gasser S
The regulation of euchromatin and heterochromatin by histones in yeast.
Journal of cell science. Supplement 1995;19():29-36.
1994: Thompson J S; Ling X; Grunstein M
Histone H3 amino terminus is required for telomeric and silent mating locus repression in yeast.
Nature 1994;369(6477):245-7.
1994: Thompson J S; Johnson L M; Grunstein M
Specific repression of the yeast silent mating locus HMR by an adjacent telomere.
Molecular and cellular biology 1994;14(1):446-55.
1993: Thompson J S; Hecht A; Grunstein M
Histones and the regulation of heterochromatin in yeast.
Cold Spring Harbor symposia on quantitative biology 1993;58():247-56.
1992: Xu H; Kim U J; Schuster T; Grunstein M
Identification of a new set of cell cycle-regulatory genes that regulate S-phase transcription of histone genes in Saccharomyces cerevisiae.
Molecular and cellular biology 1992;12(11):5249-59.
1992: Mann R K; Grunstein M
Histone H3 N-terminal mutations allow hyperactivation of the yeast GAL1 gene in vivo.
The EMBO journal 1992;11(9):3297-306.
1992: Johnson L M; Fisher-Adams G; Grunstein M
Identification of a non-basic domain in the histone H4 N-terminus required for repression of the yeast silent mating loci.
The EMBO journal 1992;11(6):2201-9.
1992: Wan J; Xu H; Grunstein M
CDC14 of Saccharomyces cerevisiae. Cloning, sequence analysis, and transcription during the cell cycle.
The Journal of biological chemistry 1992;267(16):11274-80.
1992: Durrin L K; Mann R K; Grunstein M
Nucleosome loss activates CUP1 and HIS3 promoters to fully induced levels in the yeast Saccharomyces cerevisiae.
Molecular and cellular biology 1992;12(4):1621-9.
1991: Durrin L K; Mann R K; Kayne P S; Grunstein M
Yeast histone H4 N-terminal sequence is required for promoter activation in vivo.
Cell 1991;65(6):1023-31.
1990: Grunstein M
Nucleosomes: regulators of transcription.
Trends in genetics : TIG 1990;6(12):395-400.
1990: Johnson L M; Kayne P S; Kahn E S; Grunstein M
Genetic evidence for an interaction between SIR3 and histone H4 in the repression of the silent mating loci in Saccharomyces cerevisiae.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(16):6286-90.
1990: Xu H X; Johnson L; Grunstein M
Coding and noncoding sequences at the 3' end of yeast histone H2B mRNA confer cell cycle regulation.
Molecular and cellular biology 1990;10(6):2687-94.
1990: Grunstein M
Histone function in transcription.
Annual review of cell biology 1990;6():643-78.
1989: Mullen J R; Kayne P S; Moerschell R P; Tsunasawa S; Gribskov M; Colavito-Shepanski M; Grunstein M; Sherman F; Sternglanz R
Identification and characterization of genes and mutants for an N-terminal acetyltransferase from yeast.
The EMBO journal 1989;8(7):2067-75.
1988: Han M; Grunstein M
Nucleosome loss activates yeast downstream promoters in vivo.
Cell 1988;55(6):1137-45.
1988: Kayne P S; Kim U J; Han M; Mullen J R; Yoshizaki F; Grunstein M
Extremely conserved histone H4 N terminus is dispensable for growth but essential for repressing the silent mating loci in yeast.
Cell 1988;55(1):27-39.
1988: Han M; Kim U J; Kayne P; Grunstein M
Depletion of histone H4 and nucleosomes activates the PHO5 gene in Saccharomyces cerevisiae.
The EMBO journal 1988;7(7):2221-8.
1988: Kim U J; Han M; Kayne P; Grunstein M
Effects of histone H4 depletion on the cell cycle and transcription of Saccharomyces cerevisiae.
The EMBO journal 1988;7(7):2211-9.
1987: Masson J M; Meuris P; Grunstein M; Abelson J; Miller J H
Expression of a set of synthetic suppressor tRNA(Phe) genes in Saccharomyces cerevisiae.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(19):6815-9.
1987: Han M; Chang M; Kim U J; Grunstein M
Histone H2B repression causes cell-cycle-specific arrest in yeast: effects on chromosomal segregation, replication, and transcription.
Cell 1987;48(4):589-97.
1986: Schuster T; Han M; Grunstein M
Yeast histone H2A and H2B amino termini have interchangeable functions.
Cell 1986;45(3):445-51.
1985: Choe J; Schuster T; Grunstein M
Organization, primary structure, and evolution of histone H2A and H2B genes of the fission yeast Schizosaccharomyces pombe.
Molecular and cellular biology 1985;5(11):3261-9.
1984: Travis G H; Colavito-Shepanski M; Grunstein M
Extensive purification and characterization of chromatin-bound histone acetyltransferase from Saccharomyces cerevisiae.
The Journal of biological chemistry 1984;259(23):14406-12.
1983: Wallis J W; Rykowski M; Grunstein M
Yeast histone H2B containing large amino terminus deletions can function in vivo.
Cell 1983;35(3 Pt 2):711-9.
1982: Kolodrubetz D; Rykowski M C; Grunstein M
Histone H2A subtypes associate interchangeably in vivo with histone H2B subtypes.
Proceedings of the National Academy of Sciences of the United States of America 1982;79(24):7814-8.
1982: Choe J; Kolodrubetz D; Grunstein M
The two yeast histone H2A genes encode similar protein subtypes.
Proceedings of the National Academy of Sciences of the United States of America 1982;79(5):1484-7.
1981: Rykowski M C; Wallis J W; Choe J; Grunstein M
Histone H2B subtypes are dispensable during the yeast cell cycle.
Cell 1981;25(2):477-87.
1980: Wallis J W; Hereford L; Grunstein M
Histone H2B genes of yeast encode two different proteins.
Cell 1980;22(3):799-805.

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Michael Grunstein

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Publications

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