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Michael Grunstein

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Chemicals & Drugs

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Saccharomyces cerevisiae

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TOP 3
Tasuku Kitada; Benjamin G Kuryan; Chunying Song; Nancy Nga Huynh Tran; Yong Xue; Michael Carey; Michael Grunstein
Mechanism for epigenetic variegation of gene expression at yeast telomeric heterochromatin.
Yongxin Yu; Qiongyi Zhang; Chunying Song; Autumn York; Michael F Carey; Peter A DiMaggio; Benjamin A Garcia; Michael Grunstein
Histone H3 lysine 56 methylation regulates DNA replication through its interaction with PCNA.
Adam S Sperling; Kyeong Soo Jeong; Tasuku Kitada; Michael Grunstein
Topoisomerase II binds nucleosome-free DNA and acts redundantly with topoisomerase I to enhance recruitment of RNA Pol II in budding yeast.

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All Publications

2012: Tasuku Kitada; Benjamin G Kuryan; Chunying Song; Nancy Nga Huynh Tran; Yong Xue; Michael Carey; Michael Grunstein
Mechanism for epigenetic variegation of gene expression at yeast telomeric heterochromatin.
Genes & development 2012;26(21):2443-55.
2012: Yongxin Yu; Qiongyi Zhang; Chunying Song; Autumn York; Michael F Carey; Peter A DiMaggio; Benjamin A Garcia; Michael Grunstein
Histone H3 lysine 56 methylation regulates DNA replication through its interaction with PCNA.
Molecular cell 2012;46(1):7-17.
2011: Adam S Sperling; Kyeong Soo Jeong; Tasuku Kitada; Michael Grunstein
Topoisomerase II binds nucleosome-free DNA and acts redundantly with topoisomerase I to enhance recruitment of RNA Pol II in budding yeast.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(31):12693-8.
2011: Tasuku Kitada; Thomas Schleker; Adam S Sperling; Wei Xie; Susan Gasser; Michael Grunstein
γH2A is a component of yeast heterochromatin required for telomere elongation.
Cell cycle (Georgetown, Tex.) 2011;10(2):293-300.
2010: Indranil Sinha; A Francis Stewart; Michael Grunstein; Michelle Rönnerblad; Andrej Shevchenko; Carolina Bonilla; Luke Buchanan; Mickaël Durand-Dubief; Karl Ekwall
Genome-wide mapping of histone modifications and mass spectrometry reveal H4 acetylation bias and H3K36 methylation at gene promoters in fission yeast.
Epigenomics 2010;2(3):377-93.
2009: Adam S Sperling; Michael Grunstein
Histone H3 N-terminus regulates higher order structure of yeast heterochromatin.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(32):13153-9.
2009: Mark Chin; Mike J Mason; Wei Xie; Stefano Volinia; Mike Singer; Cory Peterson; Gayane Ambartsumyan; Otaren Aimiuwu; Laura Richter; Jin Zhang; Ivan Khvorostov; Vanessa Ott; Michael Grunstein; Neta Lavon; Nissim Benvenisty; Carlo M Croce; Amander T Clark; Tim Baxter; April D Pyle; Michael A Teitell; Matteo Pelegrini; Kathrin Plath; William Lowry
Induced pluripotent stem cells and embryonic stem cells are distinguished by gene expression signatures.
Cell stem cell 2009;5(1):111-23.
2009: Wei Xie; Chunying Song; Nicolas Young; Adam S Sperling; Feng Xu; Rupa Sridharan; Anne E Conway; Benjamin A Garcia; Kathrin Plath; Amander T Clark; Michael Grunstein
Histone h3 lysine 56 acetylation is linked to the core transcriptional network in human embryonic stem cells.
Molecular cell 2009;33(4):417-27.
2008: Jonathan Houseley; Liudmilla Rubbi; Michael Grunstein; David Tollervey; Maria Vogelauer
A ncRNA modulates histone modification and mRNA induction in the yeast GAL gene cluster.
Molecular cell 2008;32(5):685-95.
2008: Tommy Kaplan; Chih Long Liu; Judith A Erkmann; John Holik; Michael Grunstein; Paul D Kaufman; Nir Friedman; Oliver J Rando
Cell cycle- and chaperone-mediated regulation of H3K56ac incorporation in yeast.
PLoS genetics 2008;4(11):e1000270.
2008: Gregory A Horwitz; Kangling Zhang; Matthew A McBrian; Michael Grunstein; Siavash K Kurdistani; Arnold J Berk
Adenovirus small e1a alters global patterns of histone modification.
Science (New York, N.Y.) 2008;321(5892):1084-5.
2007: Feng Xu; Qiongyi Zhang; Kangling Zhang; Wei Xie; Michael Grunstein
Sir2 deacetylates histone H3 lysine 56 to regulate telomeric heterochromatin structure in yeast.
Molecular cell 2007;27(6):890-900.
2007: Mickaël Durand-Dubief; Indranil Sinha; Fredrik Fagerström-Billai; Carolina Bonilla; Anthony Wright; Michael Grunstein; Karl Ekwall
Specific functions for the fission yeast Sirtuins Hst2 and Hst4 in gene regulation and retrotransposon silencing.
The EMBO journal 2007;26(10):2477-88.
2007: Mona D Shahbazian; Michael Grunstein
Functions of site-specific histone acetylation and deacetylation.
Annual review of biochemistry 2007;76():75-100.
2006: Catherine B Millar; Michael Grunstein
Genome-wide patterns of histone modifications in yeast.
Nature reviews. Molecular cell biology 2006;7(9):657-66.
2006: Catherine B Millar; Feng Xu; Kangling Zhang; Michael Grunstein
Acetylation of H2AZ Lys 14 is associated with genome-wide gene activity in yeast.
Genes & development 2006;20(6):711-22.
2005: Michael-Christopher Keogh; Siavash K Kurdistani; Stephanie A Morris; Seong Hoon Ahn; Vladimir Podolny; Sean R Collins; Maya Schuldiner; Kayu Chin; Thanuja Punna; Natalie J Thompson; Charles Boone; Andrew Emili; Jonathan S Weissman; Timothy R Hughes; Brian D Strahl; Michael Grunstein; Jack F Greenblatt; Stephen Buratowski; Nevan J Krogan
Cotranscriptional set2 methylation of histone H3 lysine 36 recruits a repressive Rpd3 complex.
Cell 2005;123(4):593-605.
2005: Marianna Wirén; Rebecca A Silverstein; Indranil Sinha; Julian Walfridsson; Hang-Mao Lee; Patricia Laurenson; Lorraine Pillus; Daniel Robyr; Michael Grunstein; Karl Ekwall
Genomewide analysis of nucleosome density histone acetylation and HDAC function in fission yeast.
The EMBO journal 2005;24(16):2906-18.
2005: Mona D Shahbazian; Kangling Zhang; Michael Grunstein
Histone H2B ubiquitylation controls processive methylation but not monomethylation by Dot1 and Set1.
Molecular cell 2005;19(2):271-7.
2005: David Seligson; Steve Horvath; Tao Shi; Hong Yu; Sheila Tze; Michael Grunstein; Siavash K Kurdistani
Global histone modification patterns predict risk of prostate cancer recurrence.
Nature 2005;435(7046):1262-6.
2005: Feng Xu; Kangling Zhang; Michael Grunstein
Acetylation in histone H3 globular domain regulates gene expression in yeast.
Cell 2005;121(3):375-85.
2004: Siavash K Kurdistani; Saeed Tavazoie; Michael Grunstein
Mapping global histone acetylation patterns to gene expression.
Cell 2004;117(6):721-33.
2004: Catherine B Millar; Siavash K Kurdistani; Michael Grunstein
Acetylation of yeast histone H4 lysine 16: a switch for protein interactions in heterochromatin and euchromatin.
Cold Spring Harbor symposia on quantitative biology 2004;69():193-200.
2004: Daniel Robyr; Siavash K Kurdistani; Michael Grunstein
Analysis of genome-wide histone acetylation state and enzyme binding using DNA microarrays.
Methods in enzymology 2004;376():289-304.
2003: Barbara G Mellone; Leslie Ball; Noriyuki Suka; Michael Grunstein; Janet F Partridge; Robin C Allshire
Centromere silencing and function in fission yeast is governed by the amino terminus of histone H3.
Current biology : CB 2003;13(20):1748-57.
2003: Siavash K Kurdistani; Michael Grunstein
In vivo protein-protein and protein-DNA crosslinking for genomewide binding microarray.
Methods (San Diego, Calif.) 2003;31(1):90-5.
2003: Daniel Robyr; Michael Grunstein
Genomewide histone acetylation microarrays.
Methods (San Diego, Calif.) 2003;31(1):83-9.
2003: Siavash K Kurdistani; Michael Grunstein
Histone acetylation and deacetylation in yeast.
Nature reviews. Molecular cell biology 2003;4(4):276-84.
2002: Amy Wang; Siavash K Kurdistani; Michael Grunstein
Requirement of Hos2 histone deacetylase for gene activity in yeast.
Science (New York, N.Y.) 2002;298(5597):1412-4.
2002: Maria Vogelauer; Liudmilla Rubbi; Isabelle Lucas; Bonita J Brewer; Michael Grunstein
Histone acetylation regulates the time of replication origin firing.
Molecular cell 2002;10(5):1223-33.
2002: Noriyuki Suka; Kunheng Luo; Michael Grunstein
Sir2p and Sas2p opposingly regulate acetylation of yeast histone H4 lysine16 and spreading of heterochromatin.
Nature genetics 2002;32(3):378-83.
2002: Arnold Kristjuhan; Jane Walker; Noriyuki Suka; Michael Grunstein; Douglas Roberts; Bradley R Cairns; Jesper Q Svejstrup
Transcriptional inhibition of genes with severe histone h3 hypoacetylation in the coding region.
Molecular cell 2002;10(4):925-33.
2002: Siavash K Kurdistani; Daniel Robyr; Saeed Tavazoie; Michael Grunstein
Genome-wide binding map of the histone deacetylase Rpd3 in yeast.
Nature genetics 2002;31(3):248-54.
2002: Kunheng Luo; Miguel A Vega-Palas; Michael Grunstein
Rap1-Sir4 binding independent of other Sir, yKu, or histone interactions initiates the assembly of telomeric heterochromatin in yeast.
Genes & development 2002;16(12):1528-39.
2002: Daniel Robyr; Yuko Suka; Ioannis Xenarios; Siavash K Kurdistani; Amy Wang; Noriyuki Suka; Michael Grunstein
Microarray deacetylation maps determine genome-wide functions for yeast histone deacetylases.
Cell 2002;109(4):437-46.
2002: Loredana Verdone; Jiansheng Wu; Kristen van Riper; Nataly Kacherovsky; Maria Vogelauer; Elton T Young; Michael Grunstein; Ernesto Di Mauro; Micaela Caserta
Hyperacetylation of chromatin at the ADH2 promoter allows Adr1 to bind in repressed conditions.
The EMBO journal 2002;21(5):1101-11.
2002: Andrew A Carmen; Lisa Milne; Michael Grunstein
Acetylation of the yeast histone H4 N terminus regulates its binding to heterochromatin protein SIR3.
The Journal of biological chemistry 2002;277(7):4778-81.
2001: Noriyuki Suka; Yuko Suka; Andrew A Carmen; Jiansheng Wu; Michael Grunstein
Highly specific antibodies determine histone acetylation site usage in yeast heterochromatin and euchromatin.
Molecular cell 2001;8(2):473-9.
2001: Jiansheng Wu; Andrew A Carmen; R Kobayashi; Noriyuki Suka; Michael Grunstein
HDA2 and HDA3 are related proteins that interact with and are essential for the activity of the yeast histone deacetylase HDA1.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(8):4391-6.
2001: Jiansheng Wu; Noriyuki Suka; M Carlson; Michael Grunstein
TUP1 utilizes histone H3/H2B-specific HDA1 deacetylase to repress gene activity in yeast.
Molecular cell 2001;7(1):117-26.
2000: Jiansheng Wu; Michael Grunstein
25 years after the nucleosome model: chromatin modifications.
Trends in biochemical sciences 2000;25(12):619-23.
2000: Maria Vogelauer; Jiansheng Wu; Noriyuki Suka; Michael Grunstein
Global histone acetylation and deacetylation in yeast.
Nature 2000;408(6811):495-8.
1999: Andrew A Carmen; P R Griffin; J R Calaycay; SE Rundlett; Yuko Suka; Michael Grunstein
Yeast HOS3 forms a novel trichostatin A-insensitive homodimer with intrinsic histone deacetylase activity.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(22):12356-61.
1999: SG Martin; Thierry Laroche; Noriyuki Suka; Michael Grunstein; Susan Gasser
Relocalization of telomeric Ku and SIR proteins in response to DNA strand breaks in yeast.
Cell 1999;97(5):621-33.
1999: Andreas Hecht; S Strahl-Bolsinger; Michael Grunstein
Mapping DNA interaction sites of chromosomal proteins. Crosslinking studies in yeast.
Methods in molecular biology (Clifton, N.J.) 1999;119():469-79.
1999: Andreas Hecht; Michael Grunstein
Mapping DNA interaction sites of chromosomal proteins using immunoprecipitation and polymerase chain reaction.
Methods in enzymology 1999;304():399-414.
1998: X J Ma; Jiansheng Wu; BA Altheim; Michael C Schultz; Michael Grunstein
Deposition-related sites K5/K12 in histone H4 are not required for nucleosome deposition in yeast.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(12):6693-8.
1998: Michael Grunstein
Yeast heterochromatin: regulation of its assembly and inheritance by histones.
Cell 1998;93(3):325-8.
1998: SE Rundlett; Andrew A Carmen; Noriyuki Suka; B M Turner; Michael Grunstein
Transcriptional repression by UME6 involves deacetylation of lysine 5 of histone H4 by RPD3.
Nature 1998;392(6678):831-5.
1998: Noriyuki Suka; Andrew A Carmen; SE Rundlett; Michael Grunstein
The regulation of gene activity by histones and the histone deacetylase RPD3.
Cold Spring Harbor symposia on quantitative biology 1998;63():391-9.
1997: Michael Grunstein
Histone acetylation in chromatin structure and transcription.
Nature 1997;389(6649):349-52.
1997: Monica Gotta; S Strahl-Bolsinger; H Renauld; Thierry Laroche; Brian Kennedy; Michael Grunstein; Susan Gasser
Localization of Sir2p: the nucleolus as a compartment for silent information regulators.
The EMBO journal 1997;16(11):3243-55.
1997: Michael Grunstein
Molecular model for telomeric heterochromatin in yeast.
Current opinion in cell biology 1997;9(3):383-7.
1997: S Strahl-Bolsinger; Andreas Hecht; Kunheng Luo; Michael Grunstein
SIR2 and SIR4 interactions differ in core and extended telomeric heterochromatin in yeast.
Genes & development 1997;11(1):83-93.
1996: S E Rundlett; Andrew A Carmen; R Kobayashi; S Bavykin; B M Turner; Michael Grunstein
HDA1 and RPD3 are members of distinct yeast histone deacetylase complexes that regulate silencing and transcription.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(25):14503-8.
1996: Andreas Hecht; S Strahl-Bolsinger; Michael Grunstein
Spreading of transcriptional repressor SIR3 from telomeric heterochromatin.
Nature 1996;383(6595):92-6.
1996: F Lenfant; R K Mann; B Thomsen; X Ling; Michael Grunstein
All four core histone N-termini contain sequences required for the repression of basal transcription in yeast.
The EMBO journal 1996;15(15):3974-85.
1996: Andrew A Carmen; S E Rundlett; Michael Grunstein
HDA1 and HDA3 are components of a yeast histone deacetylase (HDA) complex.
The Journal of biological chemistry 1996;271(26):15837-44.
1996: X J Ma; Q Lu; Michael Grunstein
A search for proteins that interact genetically with histone H3 and H4 amino termini uncovers novel regulators of the Swe1 kinase in Saccharomyces cerevisiae.
Genes & development 1996;10(11):1327-40.
1996: X Ling; T A Harkness; Michael C Schultz; G Fisher-Adams; Michael Grunstein
Yeast histone H3 and H4 amino termini are important for nucleosome assembly in vivo and in vitro: redundant and position-independent functions in assembly but not in gene regulation.
Genes & development 1996;10(6):686-99.
1995: J S Wan; R K Mann; Michael Grunstein
Yeast histone H3 and H4 N termini function through different GAL1 regulatory elements to repress and activate transcription.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(12):5664-8.
1995: G Fisher-Adams; Michael Grunstein
Yeast histone H4 and H3 N-termini have different effects on the chromatin structure of the GAL1 promoter.
The EMBO journal 1995;14(7):1468-77.
1995: Andreas Hecht; Thierry Laroche; S Strahl-Bolsinger; Susan Gasser; Michael Grunstein
Histone H3 and H4 N-termini interact with SIR3 and SIR4 proteins: a molecular model for the formation of heterochromatin in yeast.
Cell 1995;80(4):583-92.
1995: Michael Grunstein; Andreas Hecht; G Fisher-Adams; J Wan; R K Mann; S Strahl-Bolsinger; Thierry Laroche; Susan Gasser
The regulation of euchromatin and heterochromatin by histones in yeast.
Journal of cell science. Supplement 1995;19():29-36.
1994: J S Thompson; X Ling; Michael Grunstein
Histone H3 amino terminus is required for telomeric and silent mating locus repression in yeast.
Nature 1994;369(6477):245-7.
1994: J S Thompson; L M Johnson; Michael Grunstein
Specific repression of the yeast silent mating locus HMR by an adjacent telomere.
Molecular and cellular biology 1994;14(1):446-55.
1993: J S Thompson; Andreas Hecht; Michael Grunstein
Histones and the regulation of heterochromatin in yeast.
Cold Spring Harbor symposia on quantitative biology 1993;58():247-56.
1992: H Xu; U J Kim; T Schuster; Michael Grunstein
Identification of a new set of cell cycle-regulatory genes that regulate S-phase transcription of histone genes in Saccharomyces cerevisiae.
Molecular and cellular biology 1992;12(11):5249-59.
1992: R K Mann; Michael Grunstein
Histone H3 N-terminal mutations allow hyperactivation of the yeast GAL1 gene in vivo.
The EMBO journal 1992;11(9):3297-306.
1992: J Wan; H Xu; Michael Grunstein
CDC14 of Saccharomyces cerevisiae. Cloning, sequence analysis, and transcription during the cell cycle.
The Journal of biological chemistry 1992;267(16):11274-80.
1992: L M Johnson; G Fisher-Adams; Michael Grunstein
Identification of a non-basic domain in the histone H4 N-terminus required for repression of the yeast silent mating loci.
The EMBO journal 1992;11(6):2201-9.
1992: L K Durrin; R K Mann; Michael Grunstein
Nucleosome loss activates CUP1 and HIS3 promoters to fully induced levels in the yeast Saccharomyces cerevisiae.
Molecular and cellular biology 1992;12(4):1621-9.
1991: L K Durrin; R K Mann; P S Kayne; Michael Grunstein
Yeast histone H4 N-terminal sequence is required for promoter activation in vivo.
Cell 1991;65(6):1023-31.
1990: Michael Grunstein
Nucleosomes: regulators of transcription.
Trends in genetics : TIG 1990;6(12):395-400.
1990: L M Johnson; P S Kayne; E S Kahn; Michael Grunstein
Genetic evidence for an interaction between SIR3 and histone H4 in the repression of the silent mating loci in Saccharomyces cerevisiae.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(16):6286-90.
1990: H X Xu; L Johnson; Michael Grunstein
Coding and noncoding sequences at the 3' end of yeast histone H2B mRNA confer cell cycle regulation.
Molecular and cellular biology 1990;10(6):2687-94.
1990: Michael Grunstein
Histone function in transcription.
Annual review of cell biology 1990;6():643-78.
1989: J R Mullen; P S Kayne; R P Moerschell; S Tsunasawa; Michael Gribskov; M Colavito-Shepanski; Michael Grunstein; Fred Sherman; Rolf Sternglanz
Identification and characterization of genes and mutants for an N-terminal acetyltransferase from yeast.
The EMBO journal 1989;8(7):2067-75.
1988: M Han; Michael Grunstein
Nucleosome loss activates yeast downstream promoters in vivo.
Cell 1988;55(6):1137-45.
1988: P S Kayne; U J Kim; M Han; J R Mullen; F Yoshizaki; Michael Grunstein
Extremely conserved histone H4 N terminus is dispensable for growth but essential for repressing the silent mating loci in yeast.
Cell 1988;55(1):27-39.
1988: M Han; U J Kim; P Kayne; Michael Grunstein
Depletion of histone H4 and nucleosomes activates the PHO5 gene in Saccharomyces cerevisiae.
The EMBO journal 1988;7(7):2221-8.
1988: U J Kim; M Han; P Kayne; Michael Grunstein
Effects of histone H4 depletion on the cell cycle and transcription of Saccharomyces cerevisiae.
The EMBO journal 1988;7(7):2211-9.
1987: J M Masson; P Meuris; Michael Grunstein; John Abelson; Jeffrey H Miller
Expression of a set of synthetic suppressor tRNA(Phe) genes in Saccharomyces cerevisiae.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(19):6815-9.
1987: M Han; M Chang; U J Kim; Michael Grunstein
Histone H2B repression causes cell-cycle-specific arrest in yeast: effects on chromosomal segregation, replication, and transcription.
Cell 1987;48(4):589-97.
1986: T Schuster; M Han; Michael Grunstein
Yeast histone H2A and H2B amino termini have interchangeable functions.
Cell 1986;45(3):445-51.
1985: J Choe; T Schuster; Michael Grunstein
Organization, primary structure, and evolution of histone H2A and H2B genes of the fission yeast Schizosaccharomyces pombe.
Molecular and cellular biology 1985;5(11):3261-9.
1984: G H Travis; M Colavito-Shepanski; Michael Grunstein
Extensive purification and characterization of chromatin-bound histone acetyltransferase from Saccharomyces cerevisiae.
The Journal of biological chemistry 1984;259(23):14406-12.
1983: J W Wallis; M Rykowski; Michael Grunstein
Yeast histone H2B containing large amino terminus deletions can function in vivo.
Cell 1983;35(3 Pt 2):711-9.
1982: David Kolodrubetz; M C Rykowski; Michael Grunstein
Histone H2A subtypes associate interchangeably in vivo with histone H2B subtypes.
Proceedings of the National Academy of Sciences of the United States of America 1982;79(24):7814-8.
1982: J Choe; David Kolodrubetz; Michael Grunstein
The two yeast histone H2A genes encode similar protein subtypes.
Proceedings of the National Academy of Sciences of the United States of America 1982;79(5):1484-7.
1981: M C Rykowski; J W Wallis; J Choe; Michael Grunstein
Histone H2B subtypes are dispensable during the yeast cell cycle.
Cell 1981;25(2):477-87.
1980: J W Wallis; L Hereford; Michael Grunstein
Histone H2B genes of yeast encode two different proteins.
Cell 1980;22(3):799-805.