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Michael Grusby

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Andrew P R Sutherland; Nicole Joller; Vijay K Kuchroo; Sue M Liu; Monia Michaud; Michael J Grusby
IL-21 promotes CD8+ CTL activity via the transcription factor T-bet.
Ye Zhang; Guangdi Zhou; Luting Zhou; Michael J Grusby; Pedro L Herrera; Ling Li; Zhimin Liu; Xianhua Ma; Zhifang Xie; Hai Zhang; Weiping J Zhang
The zinc finger protein ZBTB20 regulates transcription of fructose-1,6-bisphosphatase 1 and β cell function in mice.
Zhaoxia Qu; Jingjiao Zhou; Jing Fu; Michael J Grusby; Meihua Jin; Huihui Ma; Markus Y Mapara; Gutian Xiao
PDLIM2 restricts Th1 and Th17 differentiation and prevents autoimmune disease.

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2013: Andrew P R Sutherland; Nicole Joller; Vijay K Kuchroo; Sue M Liu; Monia Michaud; Michael J Grusby
IL-21 promotes CD8+ CTL activity via the transcription factor T-bet.
Journal of immunology (Baltimore, Md. : 1950) 2013;190(8):3977-84.
2012: Ye Zhang; Guangdi Zhou; Luting Zhou; Michael J Grusby; Pedro L Herrera; Ling Li; Zhimin Liu; Xianhua Ma; Zhifang Xie; Hai Zhang; Weiping J Zhang
The zinc finger protein ZBTB20 regulates transcription of fructose-1,6-bisphosphatase 1 and β cell function in mice.
Gastroenterology 2012;142(7):1571-1580.e6.
2012: Zhaoxia Qu; Jingjiao Zhou; Jing Fu; Michael J Grusby; Meihua Jin; Huihui Ma; Markus Y Mapara; Gutian Xiao
PDLIM2 restricts Th1 and Th17 differentiation and prevents autoimmune disease.
Cell & bioscience 2012;2(1):23.
2010: Yukiko Hiramatsu; Akira Suto; Daisuke Kashiwakuma; Hiroko Kanari; Shin-ichiro Kagami; Kei Ikeda; Koichi Hirose; Norihiko Watanabe; Michael J Grusby; Itsuo Iwamoto; Hiroshi Nakajima
c-Maf activates the promoter and enhancer of the IL-21 gene, and TGF-beta inhibits c-Maf-induced IL-21 production in CD4+ T cells.
Journal of leukocyte biology 2010;87(4):703-12.
2010: Zhaoxia Qu; Pengrong Yan; Jing Fu; Jing Jiang; Michael J Grusby; Thomas E Smithgall; Gutian Xiao
DNA methylation-dependent repression of PDZ-LIM domain-containing protein 2 in colon cancer and its role as a potential therapeutic target.
Cancer research 2010;70(5):1766-72.
2010: John W Fathman; Michael F Gurish; Saskia Hemmers; Kevin Bonham; Daniel S Friend; Michael J Grusby; Laurie H Glimcher; Kerri A Mowen
NIP45 controls the magnitude of the type 2 T helper cell response.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(8):3663-8.
2009: Andrew Sutherland; Hai Zhang; Ye Zhang; Monia Michaud; Zhifang Xie; Mary-Elizabeth Patti; Michael J Grusby; Weiping J Zhang
Zinc finger protein Zbtb20 is essential for postnatal survival and glucose homeostasis.
Molecular and cellular biology 2009;29(10):2804-15.
2009: Alfred J Zullo; Monia Michaud; Weiping Zhang; Michael J Grusby
Identification of the small protein rich in arginine and glycine (SRAG): a newly identified nucleolar protein that can regulate cell proliferation.
The Journal of biological chemistry 2009;284(18):12504-11.
2009: Andrew Sutherland; Tom Van Belle; Andrea L Wurster; Akira Suto; Monia Michaud; Dorothy Zhang; Michael J Grusby; Matthias von Herrath
Interleukin-21 is required for the development of type 1 diabetes in NOD mice.
Diabetes 2009;58(5):1144-55.
2009: Pengrong Yan; Jing Fu; Zhaoxia Qu; Shirong Li; Takashi Tanaka; Michael J Grusby; Gutian Xiao
PDLIM2 suppresses human T-cell leukemia virus type I Tax-mediated tumorigenesis by targeting Tax into the nuclear matrix for proteasomal degradation.
Blood 2009;113(18):4370-80.
2009: Haoli Jin; Michiko K Oyoshi; Yi Le; Teresa Bianchi; Suresh Koduru; Clinton B Mathias; Lalit Kumar; Séverine Le Bras; Deborah Young; Mary Collins; Michael J Grusby; Joerg Wenzel; Thomas Bieber; Marianne Boes; Leslie E Silberstein; Hans C Oettgen; Raif S Geha
IL-21R is essential for epicutaneous sensitization and allergic skin inflammation in humans and mice.
The Journal of clinical investigation 2009;119(1):47-60.
2008: Zhifang Xie; Hai Zhang; Wenwei Tsai; Ye Zhang; Yu Du; Jigen Zhong; Claude Szpirer; Minghua Zhu; Xuetao Cao; Michelle Craig Barton; Michael J Grusby; Weiping J Zhang
Zinc finger protein ZBTB20 is a key repressor of alpha-fetoprotein gene transcription in liver.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(31):10859-64.
2008: Akira Suto; Daisuke Kashiwakuma; Shin-ichiro Kagami; Koichi Hirose; Norihiko Watanabe; Kotaro Yokote; Yasushi Saito; Toshinori Nakayama; Michael J Grusby; Itsuo Iwamoto; Hiroshi Nakajima
Development and characterization of IL-21-producing CD4+ T cells.
The Journal of experimental medicine 2008;205(6):1369-79.
2008: Tao Zheng; Wei Liu; Sun-Young Oh; Zhou Zhu; Buqu Hu; Robert J Homer; Lauren Cohn; Michael J Grusby; Jack A Elias
IL-13 receptor alpha2 selectively inhibits IL-13-induced responses in the murine lung.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(1):522-9.
2007: Attila Becskei; Michael J Grusby
Contribution of IL-12R mediated feedback loop to Th1 cell differentiation.
FEBS letters 2007;581(27):5199-206.
2007: Maki Touma; Valeria Antonini; Manoj Kumar; Stephanie L Osborn; April M Bobenchik; Derin B Keskin; John E Connolly; Michael J Grusby; Ellis L Reinherz; Linda K Clayton
Functional role for I kappa BNS in T cell cytokine regulation as revealed by targeted gene disruption.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(3):1681-92.
2007: Takashi Tanaka; Michael J Grusby; Tsuneyasu Kaisho
PDLIM2-mediated termination of transcription factor NF-kappaB activation by intranuclear sequestration and degradation of the p65 subunit.
Nature immunology 2007;8(6):584-91.
2007: Masakiyo Nakahira; Takashi Tanaka; Bryanne E Robson; Joseph P Mizgerd; Michael J Grusby
Regulation of signal transducer and activator of transcription signaling by the tyrosine phosphatase PTP-BL.
Immunity 2007;26(2):163-76.
2007: Chengjiang Gao; Hongtao Guo; Zhiyong Mi; Michael J Grusby; Paul C Kuo
Osteopontin induces ubiquitin-dependent degradation of STAT1 in RAW264.7 murine macrophages.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(3):1870-81.
2007: Michael P Keane; Brigitte N Gomperts; S Sam Weigt; Ying Ying Xue; Marie D Burdick; Hiromi Nakamura; David A Zisman; Abbas Ardehali; Rajan Saggar; Joseph P Lynch; Cory M Hogaboam; Steven Kunkel; Nicholas W Lukacs; David J Ross; Michael J Grusby; Robert M Strieter; John A Belperio
IL-13 is pivotal in the fibro-obliterative process of bronchiolitis obliterans syndrome.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(1):511-9.
2006: Akira Suto; Andrea L Wurster; Steven L Reiner; Michael J Grusby
IL-21 inhibits IFN-gamma production in developing Th1 cells through the repression of Eomesodermin expression.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(6):3721-7.
2006: John Pesce; Mallika Kaviratne; Thirumalai Ramalingam; Robert W Thompson; Joseph F Urban; Allen W Cheever; Deborah A Young; Mary Collins; Michael J Grusby; Thomas A Wynn
The IL-21 receptor augments Th2 effector function and alternative macrophage activation.
The Journal of clinical investigation 2006;116(7):2044-55.
2006: Haochu Huang; John F Kearney; Michael J Grusby; Christophe Benoist; Diane Mathis
Induction of tolerance in arthritogenic B cells with receptors of differing affinity for self-antigen.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(10):3734-9.
2005: Takashi Tanaka; Michelle A Soriano; Michael J Grusby
SLIM is a nuclear ubiquitin E3 ligase that negatively regulates STAT signaling.
Immunity 2005;22(6):729-36.
2005: Devangi S Mehta; Andrea L Wurster; Amy S Weinmann; Michael J Grusby
NFATc2 and T-bet contribute to T-helper-cell-subset-specific regulation of IL-21 expression.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(6):2016-21.
2004: Devangi S Mehta; Andrea L Wurster; Michael J Grusby
Biology of IL-21 and the IL-21 receptor.
Immunological reviews 2004;202():84-95.
2004: Qian Liu; Cristin Arseculeratne; Zhugong Liu; Jason K Whitmire; Michael J Grusby; Fred D Finkelman; Thomas Darling; Allen W Cheever; James Swearengen; Joseph F Urban; William C Gause
Simultaneous deficiency in CD28 and STAT6 results in chronic ectoparasite-induced inflammatory skin disease.
Infection and immunity 2004;72(7):3706-15.
2004: Yoshiyuki Satake; Bruno L Diaz; Barbara Balestrieri; Bing K Lam; Yoshihide Kanaoka; Michael J Grusby; Jonathan P Arm
Role of group V phospholipase A2 in zymosan-induced eicosanoid generation and vascular permeability revealed by targeted gene disruption.
The Journal of biological chemistry 2004;279(16):16488-94.
2004: Tanuja Chitnis; Alan D Salama; Michael J Grusby; Mohamed H Sayegh; Samia J Khoury
Defining Th1 and Th2 immune responses in a reciprocal cytokine environment in vivo.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(7):4260-5.
2004: Margaret M Mentink-Kane; Allen W Cheever; Robert W Thompson; Danielle M Hari; Narcis B Kabatereine; Birgitte J Vennervald; John H Ouma; Joseph K Mwatha; Frances M Jones; Debra D Donaldson; Michael J Grusby; David W Dunne; Thomas A Wynn
IL-13 receptor alpha 2 down-modulates granulomatous inflammation and prolongs host survival in schistosomiasis.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(2):586-90.
2003: Hak-Ling Ma; Matthew J Whitters; Richard F Konz; Mayra Senices; Deborah A Young; Michael J Grusby; Mary Collins; Kyriaki Dunussi-Joannopoulos
IL-21 activates both innate and adaptive immunity to generate potent antitumor responses that require perforin but are independent of IFN-gamma.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(2):608-15.
2003: Jay H Bream; Rafael E Curiel; Cheng-Rong Yu; Charles E Egwuagu; Michael J Grusby; Thomas M Aune; Howard A Young
IL-4 synergistically enhances both IL-2- and IL-12-induced IFN-gamma expression in murine NK cells.
Blood 2003;102(1):207-14.
2003: Omid Akbari; Philippe Stock; Everett Meyer; Mitchell Kronenberg; Stephane Sidobre; Toshinori Nakayama; Masaru Taniguchi; Michael J Grusby; Rosemarie H Dekruyff; Dale T Umetsu
Essential role of NKT cells producing IL-4 and IL-13 in the development of allergen-induced airway hyperreactivity.
Nature medicine 2003;9(5):582-8.
2003: Devangi S Mehta; Andrea L Wurster; Matthew J Whitters; Deborah A Young; Mary Collins; Michael J Grusby
IL-21 induces the apoptosis of resting and activated primary B cells.
Journal of immunology (Baltimore, Md. : 1950) 2003;170(8):4111-8.
2003: Nancy Wood; Matthew J Whitters; Bruce A Jacobson; JoAnn Witek; Joseph P Sypek; Marion T Kasaian; Michael J Eppihimer; Michelle Unger; Takashi Tanaka; Samuel J Goldman; Mary Collins; Debra D Donaldson; Michael J Grusby
Enhanced interleukin (IL)-13 responses in mice lacking IL-13 receptor alpha 2.
The Journal of experimental medicine 2003;197(6):703-9.
2003: Monica G Chiaramonte; Margaret M Mentink-Kane; Bruce A Jacobson; Allen W Cheever; Matthew J Whitters; Mary E P Goad; Anthony Wong; Mary Collins; Debra D Donaldson; Michael J Grusby; Thomas A Wynn
Regulation and function of the interleukin 13 receptor alpha 2 during a T helper cell type 2-dominant immune response.
The Journal of experimental medicine 2003;197(6):687-701.
2003: Doo Ryeon Chung; Dennis L Kasper; Ronald J Panzo; Tanuja Chitnis; Michael J Grusby; Mohamed H Sayegh; Arthur O Tzianabos; Tanuja Chtinis
CD4+ T cells mediate abscess formation in intra-abdominal sepsis by an IL-17-dependent mechanism.
Journal of immunology (Baltimore, Md. : 1950) 2003;170(4):1958-63.
2002: Joanne L Eyles; Donald Metcalf; Michael J Grusby; Douglas J Hilton; Robyn Starr
Negative regulation of interleukin-12 signaling by suppressor of cytokine signaling-1.
The Journal of biological chemistry 2002;277(46):43735-40.
2002: Andrea L Wurster; Vikki L Rodgers; Abhay R Satoskar; Matthew J Whitters; Deborah A Young; Mary Collins; Michael J Grusby
Interleukin 21 is a T helper (Th) cell 2 cytokine that specifically inhibits the differentiation of naive Th cells into interferon gamma-producing Th1 cells.
The Journal of experimental medicine 2002;196(7):969-77.
2002: Alison Finnegan; Michael J Grusby; Charles D Kaplan; Shannon K O'Neill; Hermann Eibel; Tamas Koreny; Matyas Czipri; Katalin Mikecz; Jian Zhang
IL-4 and IL-12 regulate proteoglycan-induced arthritis through Stat-dependent mechanisms.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(6):3345-52.
2002: Andrea L Wurster; Vikki L Rodgers; Morris F White; Thomas L Rothstein; Michael J Grusby
Interleukin-4-mediated protection of primary B cells from apoptosis through Stat6-dependent up-regulation of Bcl-xL.
The Journal of biological chemistry 2002;277(30):27169-75.
2002: Marion T Kasaian; Matthew J Whitters; Laura L Carter; Leslie D Lowe; Jason Jussif; Bijia Deng; Kaley A Johnson; JoAnn S Witek; Mayra Senices; Richard F Konz; Andrea L Wurster; Debra D Donaldson; Mary Collins; Deborah A Young; Michael J Grusby
IL-21 limits NK cell responses and promotes antigen-specific T cell activation: a mediator of the transition from innate to adaptive immunity.
Immunity 2002;16(4):559-69.
2002: Andrea L Wurster; Dominic J Withers; Tohru Uchida; Morris F White; Michael J Grusby
Stat6 and IRS-2 cooperate in interleukin 4 (IL-4)-induced proliferation and differentiation but are dispensable for IL-4-dependent rescue from apoptosis.
Molecular and cellular biology 2002;22(1):117-26.
2001: Tanuja Chitnis; Nader Najafian; Christina Benou; Alan D Salama; Michael J Grusby; Mohamed H Sayegh; Samia J Khoury
Effect of targeted disruption of STAT4 and STAT6 on the induction of experimental autoimmune encephalomyelitis.
The Journal of clinical investigation 2001;108(5):739-47.
2001: A M Reimold; Neal N Iwakoshi; J Manis; P Vallabhajosyula; E Szomolanyi-Tsuda; Ellen M Gravallese; D Friend; Michael J Grusby; F Alt; Laurie H Glimcher
Plasma cell differentiation requires the transcription factor XBP-1.
Nature 2001;412(6844):300-7.
2001: Massoud Daheshia; Daniel S Friend; Michael J Grusby; K Frank Austen; Howard Katz
Increased severity of local and systemic anaphylactic reactions in gp49B1-deficient mice.
The Journal of experimental medicine 2001;194(2):227-34.
2001: Mark A Exley; N J Bigley; Olivia Cheng; Syed Muhammad Ali Tahir; ST Smiley; Quincy L Carter; Harold F Stills; Michael J Grusby; Yasuhiko Koezuka; M Taniguchi; Steven P Balk
CD1d-reactive T-cell activation leads to amelioration of disease caused by diabetogenic encephalomyocarditis virus.
Journal of leukocyte biology 2001;69(5):713-8.
2000: VA Lawless; Shangming Zhang; Osman Nidai Ozes; Heather A Bruns; I Oldham; Timothy Hoey; Michael J Grusby; M H Kaplan
Stat4 regulates multiple components of IFN-gamma-inducing signaling pathways.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(12):6803-8.
2000: Andrea L Wurster; Takashi Tanaka; Michael J Grusby
The biology of Stat4 and Stat6.
Oncogene 2000;19(21):2577-84.
2000: Boris Nikolic; S Lee; Roderick T Bronson; Michael J Grusby; Megan Sykes
Th1 and Th2 mediate acute graft-versus-host disease, each with distinct end-organ targets.
The Journal of clinical investigation 2000;105(9):1289-98.
1999: M H Kaplan; Andrea L Wurster; ST Smiley; Michael J Grusby
Stat6-dependent and -independent pathways for IL-4 production.
Journal of immunology (Baltimore, Md. : 1950) 1999;163(12):6536-40.
1999: Christopher J Ong; S Ip; Soo-Jeet Teh; C Wong; Frank R Jirik; Michael J Grusby; Hung-Sia Teh
A role for T helper 2 cells in mediating skin fibrosis in tight-skin mice.
Cellular immunology 1999;196(1):60-8.
1999: JI Kim; I-Cheng Ho; Michael J Grusby; Laurie H Glimcher
The transcription factor c-Maf controls the production of interleukin-4 but not other Th2 cytokines.
Immunity 1999;10(6):745-51.
1999: G Eberl; Rosemary K Lees; ST Smiley; M Taniguchi; Michael J Grusby; H Robson MacDonald
Tissue-specific segregation of CD1d-dependent and CD1d-independent NK T cells.
Journal of immunology (Baltimore, Md. : 1950) 1999;162(11):6410-9.
1999: JI Kim; T Li; I-Cheng Ho; Michael J Grusby; Laurie H Glimcher
Requirement for the c-Maf transcription factor in crystallin gene regulation and lens development.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(7):3781-5.
1999: I-Cheng Ho; M H Kaplan; L Jackson-Grusby; Laurie H Glimcher; Michael J Grusby
Marking IL-4-producing cells by knock-in of the IL-4 gene.
International immunology 1999;11(2):243-7.
1998: N Burdin; Laurent Brossay; Yasuhiko Koezuka; ST Smiley; Michael J Grusby; M Gui; M Taniguchi; K Hayakawa; Mitchell Kronenberg
Selective ability of mouse CD1 to present glycolipids: alpha-galactosylceramide specifically stimulates V alpha 14+ NK T lymphocytes.
Journal of immunology (Baltimore, Md. : 1950) 1998;161(7):3271-81.
1998: M H Kaplan; Andrea L Wurster; Michael J Grusby
A signal transducer and activator of transcription (Stat)4-independent pathway for the development of T helper type 1 cells.
The Journal of experimental medicine 1998;188(6):1191-6.
1998: Mohamed Oukka; I-Cheng Ho; FC de la Brousse; Timothy Hoey; Michael J Grusby; Laurie H Glimcher
The transcription factor NFAT4 is involved in the generation and survival of T cells.
Immunity 1998;9(3):295-304.
1998: M H Kaplan; Michael J Grusby
Regulation of T helper cell differentiation by STAT molecules.
Journal of leukocyte biology 1998;64(1):2-5.
1998: M H Kaplan; C Daniel; Ulrike Schindler; Michael J Grusby
Stat proteins control lymphocyte proliferation by regulating p27Kip1 expression.
Molecular and cellular biology 1998;18(4):1996-2003.
1998: AM Ranger; Michael J Grusby; M R Hodge; Ellen M Gravallese; FC de la Brousse; Timothy Hoey; CS Mickanin; H Scott Baldwin; Laurie H Glimcher
The transcription factor NF-ATc is essential for cardiac valve formation.
Nature 1998;392(6672):186-90.
1998: M H Kaplan; JR Whitfield; Dov L Boros; Michael J Grusby
Th2 cells are required for the Schistosoma mansoni egg-induced granulomatous response.
Journal of immunology (Baltimore, Md. : 1950) 1998;160(4):1850-6.
1998: AM Ranger; M R Hodge; Ellen M Gravallese; Mohamed Oukka; L Davidson; F W Alt; FC de la Brousse; Timothy Hoey; Michael J Grusby; Laurie H Glimcher
Delayed lymphoid repopulation with defects in IL-4-driven responses produced by inactivation of NF-ATc.
Immunity 1998;8(1):125-34.
1997: ST Smiley; T N Stitt; Michael J Grusby
Cross-linking of protein S bound to lymphocytes promotes aggregation and inhibits proliferation.
Cellular immunology 1997;181(2):120-6.
1997: ST Smiley; S N Boyer; M J Heeb; J H Griffin; Michael J Grusby
Protein S is inducible by interleukin 4 in T cells and inhibits lymphoid cell procoagulant activity.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(21):11484-9.
1997: ST Smiley; Michael J Grusby
Dual-receptor T cells expressing one self-restricted TCR.
Scandinavian journal of immunology 1997;45(6):726-30.
1997: Michael J Grusby
Stat4- and Stat6-deficient mice as models for manipulating T helper cell responses.
Biochemical Society transactions 1997;25(2):359-60.
1997: Richard S Lee; Michael J Grusby; Terri M Laufer; R Colvin; Laurie H Glimcher; Hugh Auchincloss
CD8+ effector cells responding to residual class I antigens, with help from CD4+ cells stimulated indirectly, cause rejection of "major histocompatibility complex-deficient" skin grafts.
Transplantation 1997;63(8):1123-33.
1997: ST Smiley; M H Kaplan; Michael J Grusby
Immunoglobulin E production in the absence of interleukin-4-secreting CD1-dependent cells.
Science (New York, N.Y.) 1997;275(5302):977-9.
1996: M H Kaplan; S N Boyer; Michael J Grusby
Genomic organization of the murine CTL lipase gene.
Genomics 1996;35(3):606-9.
1996: M H Kaplan; Y L Sun; Timothy Hoey; Michael J Grusby
Impaired IL-12 responses and enhanced development of Th2 cells in Stat4-deficient mice.
Nature 1996;382(6587):174-7.
1996: M R Hodge; AM Ranger; F Charles de la Brousse; Timothy Hoey; Michael J Grusby; Laurie H Glimcher
Hyperproliferation and dysregulation of IL-4 expression in NF-ATp-deficient mice.
Immunity 1996;4(4):397-405.
1996: M H Kaplan; U Schindler; ST Smiley; Michael J Grusby
Stat6 is required for mediating responses to IL-4 and for development of Th2 cells.
Immunity 1996;4(3):313-9.
1996: D J Steele; T M Laufer; ST Smiley; Y Ando; Michael J Grusby; Laurie H Glimcher; Hugh Auchincloss
Two levels of help for B cell alloantibody production.
The Journal of experimental medicine 1996;183(2):699-703.
1996: A M Reimold; Michael J Grusby; Bela Kosaras; J W Fries; R Mori; S Maniwa; I M Clauss; T Collins; Richard Sidman; M J Glimcher; Laurie H Glimcher
Chondrodysplasia and neurological abnormalities in ATF-2-deficient mice.
Nature 1996;379(6562):262-5.
1996: ST Smiley; A Y Rudensky; Laurie H Glimcher; Michael J Grusby
Truncation of the class II beta-chain cytoplasmic domain influences the level of class II/invariant chain-derived peptide complexes.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(1):241-4.
1995: H R Chakkalath; C M Theodos; J S Markowitz; Michael J Grusby; Laurie H Glimcher; Richard G Titus
Class II major histocompatibility complex-deficient mice initially control an infection with Leishmania major but succumb to the disease.
The Journal of infectious diseases 1995;171(5):1302-8.
1995: H Wecker; Michael J Grusby; Hugh Auchincloss
Effector cells must recognize antigens expressed in the graft to cause efficient skin graft rejection in SCID mice.
Transplantation 1995;59(8):1223-7.
1995: ST Smiley; T M Laufer; David Lo; Laurie H Glimcher; Michael J Grusby
Transgenic mice expressing MHC class II molecules with truncated A beta cytoplasmic domains reveal signaling-independent defects in antigen presentation.
International immunology 1995;7(4):665-77.
1995: Michael J Grusby; Laurie H Glimcher
Immune responses in MHC class II-deficient mice.
Annual review of immunology 1995;13():417-35.
1994: A C Avery; J S Markowitz; Michael J Grusby; Laurie H Glimcher; Harvey Cantor
Activation of T cells by superantigen in class II-negative mice.
Journal of immunology (Baltimore, Md. : 1950) 1994;153(11):4853-61.
1994: P Mombaerts; E Mizoguchi; H G Ljunggren; J Iacomini; H Ishikawa; L Wang; Michael J Grusby; Laurie H Glimcher; H J Winn; A K Bhan
Peripheral lymphoid development and function in TCR mutant mice.
International immunology 1994;6(7):1061-70.
1994: G P Linette; Michael J Grusby; S M Hedrick; T H Hansen; Laurie H Glimcher; Stanley J Korsmeyer
Bcl-2 is upregulated at the CD4+ CD8+ stage during positive selection and promotes thymocyte differentiation at several control points.
Immunity 1994;1(3):197-205.
1994: R S Lee; Michael J Grusby; Laurie H Glimcher; H J Winn; Hugh Auchincloss
Indirect recognition by helper cells can induce donor-specific cytotoxic T lymphocytes in vivo.
The Journal of experimental medicine 1994;179(3):865-72.
1993: A L Crump; Michael J Grusby; Laurie H Glimcher; Harvey Cantor
Thymocyte development in major histocompatibility complex-deficient mice: evidence for stochastic commitment to the CD4 and CD8 lineages.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(22):10739-43.
1993: P Mombaerts; E Mizoguchi; Michael J Grusby; Laurie H Glimcher; A K Bhan; Susumu Tonegawa
Spontaneous development of inflammatory bowel disease in T cell receptor mutant mice.
Cell 1993;75(2):274-82.
1993: T M Laufer; M G von Herrath; Michael J Grusby; M B Oldstone; Laurie H Glimcher
Autoimmune diabetes can be induced in transgenic major histocompatibility complex class II-deficient mice.
The Journal of experimental medicine 1993;178(2):589-96.
1993: M D Todd; Michael J Grusby; James A Lederer; Elizabeth Lacy; Andrew H Lichtman; Laurie H Glimcher
Transcription of the interleukin 4 gene is regulated by multiple promoter elements.
The Journal of experimental medicine 1993;177(6):1663-74.
1993: Michael J Grusby; Hugh Auchincloss; R Lee; R S Johnson; J P Spencer; M Zijlstra; Rudolf Jaenisch; V E Papaioannou; Laurie H Glimcher
Mice lacking major histocompatibility complex class I and class II molecules.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(9):3913-7.
1993: J S Markowitz; Hugh Auchincloss; Michael J Grusby; Laurie H Glimcher
Class II-positive hematopoietic cells cannot mediate positive selection of CD4+ T lymphocytes in class II-deficient mice.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(7):2779-83.
1993: J S Markowitz; P R Rogers; Michael J Grusby; David Parker; Laurie H Glimcher
B lymphocyte development and activation independent of MHC class II expression.
Journal of immunology (Baltimore, Md. : 1950) 1993;150(4):1223-33.
1993: Harvey Cantor; A L Crump; V K Raman; H Liu; J S Markowitz; Michael J Grusby; L H Glimcher
Immunoregulatory effects of superantigens: interactions of staphylococcal enterotoxins with host MHC and non-MHC products.
Immunological reviews 1993;131():27-42.
1991: Michael J Grusby; R S Johnson; V E Papaioannou; Laurie H Glimcher
Depletion of CD4+ T cells in major histocompatibility complex class II-deficient mice.
Science (New York, N.Y.) 1991;253(5026):1417-20.
1991: Patricia W Finn; C J Kara; Michael J Grusby; V Folsom; Laurie H Glimcher
Upstream elements of the MHC class II E beta gene active in B cells.
Journal of immunology (Baltimore, Md. : 1950) 1991;146(11):4011-5.
1990: Michael J Grusby; S C Mitchell; N Nabavi; Laurie H Glimcher
Casein expression in cytotoxic T lymphocytes.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(17):6897-901.
1990: Michael J Grusby; N Nabavi; H Wong; R F Dick; J A Bluestone; M C Schotz; Laurie H Glimcher
Cloning of an interleukin-4 inducible gene from cytotoxic T lymphocytes and its identification as a lipase.
Cell 1990;60(3):451-9.
1990: N Nabavi; Michael J Grusby; Patricia W Finn; D J Wolgemuth; Laurie H Glimcher
Identification of an IL-4-inducible gene expressed in differentiating lymphocytes and male germ cells.
Developmental immunology 1990;1(1):19-30.