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Michael Gschwendt

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Chemicals & Drugs

Living Beings

Mice

Phenomena

Phosphorylation

Anatomy

Physiology

Enzyme Activation

Genes & Molecular Sequences

Amino Acid Sequence

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Molecular Sequence Data

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Co-Publications
Name
38
Kittstein, W
32
Marks, Friedrich
8
Rincke, Gabriele
6
Stempka, Luise
4
Fürstenberger, Gerhard
3
Johannes, FJ
2
Ostrowski, Jerzy
2
Schullery, Daniel
2
Bomsztyk, Karol
2
Denisenko, Oleg
1
Aebersold, Ruedi
1
Bossemeyer, Dirk
1
Martinon, Fabio
1
Meylan, Etienne
1
Möller, Peter

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Publications

TOP 3
Gschwendt Michael; Stempka Luise
Expression and purification of protein kinase Cdelta from bacteria.
Meylan Etienne; Martinon Fabio; Thome Margot; Gschwendt Michael; Tschopp Jürg
RIP4 (DIK/PKK), a novel member of the RIP kinase family, activates NF-kappa B and is processed during apoptosis.
Bhr C; Rohwer A; Stempka L; Rincke G; Marks F; Gschwendt M
DIK, a novel protein kinase that interacts with protein kinase Cdelta. Cloning, characterization, and gene analysis.

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All Publications

2003: Gschwendt Michael; Stempka Luise
Expression and purification of protein kinase Cdelta from bacteria.
Methods in molecular biology (Clifton, N.J.) 2003;233():35-42.
2002: Meylan Etienne; Martinon Fabio; Thome Margot; Gschwendt Michael; Tschopp Jürg
RIP4 (DIK/PKK), a novel member of the RIP kinase family, activates NF-kappa B and is processed during apoptosis.
EMBO reports 2002;3(12):1201-8.
2000: Bhr C; Rohwer A; Stempka L; Rincke G; Marks F; Gschwendt M
DIK, a novel protein kinase that interacts with protein kinase Cdelta. Cloning, characterization, and gene analysis.
The Journal of biological chemistry 2000;275(46):36350-7.
2000: Ostrowski J; Schullery D S; Denisenko O N; Higaki Y; Watts J; Aebersold R; Stempka L; Gschwendt M; Bomsztyk K
Role of tyrosine phosphorylation in the regulation of the interaction of heterogenous nuclear ribonucleoprotein K protein with its protein and RNA partners.
The Journal of biological chemistry 2000;275(5):3619-28.
1999: Häussermann S; Kittstein W; Rincke G; Johannes F J; Marks F; Gschwendt M
Proteolytic cleavage of protein kinase Cmu upon induction of apoptosis in U937 cells.
FEBS letters 1999;462(3):442-6.
1999: Rohwer A; Kittstein W; Marks F; Gschwendt M
Cloning, expression and characterization of an A6-related protein.
European journal of biochemistry / FEBS 1999;263(2):518-25.
1999: Schullery D S; Ostrowski J; Denisenko O N; Stempka L; Shnyreva M; Suzuki H; Gschwendt M; Bomsztyk K
Regulated interaction of protein kinase Cdelta with the heterogeneous nuclear ribonucleoprotein K protein.
The Journal of biological chemistry 1999;274(21):15101-9.
1999: Stempka L; Schnölzer M; Radke S; Rincke G; Marks F; Gschwendt M
Requirements of protein kinase cdelta for catalytic function. Role of glutamic acid 500 and autophosphorylation on serine 643.
The Journal of biological chemistry 1999;274(13):8886-92.
1999: Gschwendt M
Protein kinase C delta.
European journal of biochemistry / FEBS 1999;259(3):555-64.
1998: von Reyher U; Sträter J; Kittstein W; Gschwendt M; Krammer P H; Möller P
Colon carcinoma cells use different mechanisms to escape CD95-mediated apoptosis.
Cancer research 1998;58(3):526-34.
1998: Gschwendt M; Kittstein W; Johannes F J
Differential effects of suramin on protein kinase C isoenzymes. A novel tool for discriminating protein kinase C activities.
FEBS letters 1998;421(2):165-8.
1997: Gschwendt M; Johannes F J; Kittstein W; Marks F
Regulation of protein kinase Cmu by basic peptides and heparin. Putative role of an acidic domain in the activation of the kinase.
The Journal of biological chemistry 1997;272(33):20742-6.
1997: Stempka L; Girod A; Müller H J; Rincke G; Marks F; Gschwendt M; Bossemeyer D
Phosphorylation of protein kinase Cdelta (PKCdelta) at threonine 505 is not a prerequisite for enzymatic activity. Expression of rat PKCdelta and an alanine 505 mutant in bacteria in a functional form.
The Journal of biological chemistry 1997;272(10):6805-11.
1996: Rennecke J; Johannes F J; Richter K H; Kittstein W; Marks F; Gschwendt M
Immunological demonstration of protein kinase C mu in murine tissues and various cell lines. Differential recognition of phosphorylated forms and lack of down-regulation upon 12-O-tetradecanoylphorphol-13-acetate treatment of cells.
European journal of biochemistry / FEBS 1996;242(2):428-32.
1996: Gschwendt M; Dieterich S; Rennecke J; Kittstein W; Mueller H J; Johannes F J
Inhibition of protein kinase C mu by various inhibitors. Differentiation from protein kinase c isoenzymes.
FEBS letters 1996;392(2):77-80.
1995: Kielbassa K; Müller H J; Meyer H E; Marks F; Gschwendt M
Protein kinase C delta-specific phosphorylation of the elongation factor eEF-alpha and an eEF-1 alpha peptide at threonine 431.
The Journal of biological chemistry 1995;270(11):6156-62.
1995: Gschwendt M; Fürstenberger G; Leibersperger H; Kittstein W; Lindner D; Rudolph C; Barth H; Kleinschroth J; Marmé D; Schächtele C
Lack of an effect of novel inhibitors with high specificity for protein kinase C on the action of the phorbol ester 12-O-tetradecanoylphorbol-13-acetate on mouse skin in vivo.
Carcinogenesis 1995;16(1):107-11.
1995: Gschwendt M; Kittstein W; Kielbassa K; Marks F
Protein kinase C delta accepts GTP for autophosphorylation.
Biochemical and biophysical research communications 1995;206(2):614-20.
1994: Zang R; Müller H J; Kielbassa K; Marks F; Gschwendt M
Partial purification of a type eta protein kinase C from murine brain: separation from other protein kinase C isoenzymes and characterization.
The Biochemical journal 1994;304 ( Pt 2)():641-7.
1994: Gschwendt M; Kielbassa K; Kittstein W; Marks F
Tyrosine phosphorylation and stimulation of protein kinase C delta from porcine spleen by src in vitro. Dependence on the activated state of protein kinase C delta.
FEBS letters 1994;347(1):85-9.
1994: Gschwendt M; Müller H J; Kielbassa K; Zang R; Kittstein W; Rincke G; Marks F
Rottlerin, a novel protein kinase inhibitor.
Biochemical and biophysical research communications 1994;199(1):93-8.
1994: Gschwendt M; Kittstein W; Marks F
Elongation factor-2 kinase: effective inhibition by the novel protein kinase inhibitor rottlerin and relative insensitivity towards staurosporine.
FEBS letters 1994;338(1):85-8.
1993: Gschwendt M; Kittstein W; Marks F
Protein kinase C forms a complex with and phosphorylates the GTPase activating protein GAP: phosphorylation by PKC is dependent on tyrosine phosphorylation of GAP and/or a GAP-associated protein.
Biochemical and biophysical research communications 1993;194(1):571-6.
1992: Gschwendt M; Kittstein W; Lindner D; Marks F
Differential inhibition by staurosporine of phorbol ester, bryostatin and okadaic acid effects on mouse skin.
Cancer letters 1992;66(2):139-46.
1992: Gschwendt M; Leibersperger H; Kittstein W; Marks F
Protein kinase C zeta and eta in murine epidermis. TPA induces down-regulation of PKC eta but not PKC zeta.
FEBS letters 1992;307(2):151-5.
1992: Lindner D; Gschwendt M; Marks F
Phorbol ester-induced down-regulation of the 80-kDa myristoylated alanine-rich C-kinase substrate-related protein in Swiss 3T3 fibroblasts. Inhibition by staurosporine.
The Journal of biological chemistry 1992;267(1):24-6.
1991: Gschwendt M; Leibersperger H; Rincke G; Marks F
Immunological demonstration of epsilon PKC. Murine tissue distribution, ontogeny, cellular localization and translocation.
FEBS letters 1991;290(1-2):115-8.
1991: Leibersperger H; Gschwendt M; Gernold M; Marks F
Immunological demonstration of a calcium-unresponsive protein kinase C of the delta-type in different species and murine tissues. Predominance in epidermis.
The Journal of biological chemistry 1991;266(22):14778-84.
1991: Lindner D; Gschwendt M; Marks F
Down-regulation of protein kinase C in Swiss 3T3 fibroblasts is independent of its phosphorylating activity.
Biochemical and biophysical research communications 1991;176(3):1227-31.
1991: Gschwendt M; Kittstein W; Marks F
Protein kinase C activation by phorbol esters: do cysteine-rich regions and pseudosubstrate motifs play a role?
Trends in biochemical sciences 1991;16(5):167-9.
1990: Leibersperger H; Gschwendt M; Marks F
Purification and characterization of a calcium-unresponsive, phorbol ester/phospholipid-activated protein kinase from porcine spleen.
The Journal of biological chemistry 1990;265(27):16108-15.
1989: Gschwendt M; Leibersperger H; Marks F
Differentiative action of K252a on protein kinase C and a calcium-unresponsive, phorbol ester/phospholipid-activated protein kinase.
Biochemical and biophysical research communications 1989;164(3):974-82.
1989: Gschwendt M; Kittstein W; Mieskes G; Marks F
A type 2A protein phosphatase dephosphorylates the elongation factor 2 and is stimulated by the phorbol ester TPA in mouse epidermis in vivo.
FEBS letters 1989;257(2):357-60.
1989: Gschwendt M; Kittstein W; Horn F; Leibersperger H; Marks F
A phorbol ester and phospholipid-activated, calcium-unresponsive protein kinase in mouse epidermis: characterization and separation from protein kinase C.
Journal of cellular biochemistry 1989;40(3):295-307.
1989: Gschwendt M; Kittstein W; Marks F
Cyclosporine A suppresses an early process in phorbol ester action.
Cancer letters 1989;46(2):113-5.
1989: Gschwendt M; Kittstein W; Marks F
The immunosuppressant FK-506, like cyclosporins and didemnin B, inhibits calmodulin-dependent phosphorylation of the elongation factor 2 in vitro and biological effects of the phorbol ester TPA on mouse skin in vivo.
Immunobiology 1989;179(1):1-7.
1988: Gschwendt M; Kittstein W; Marks F
Sequence similarity between cyclophilin and elongation factor 2.
The Biochemical journal 1988;256(3):1061.
1988: Gschwendt M; Kittstein W; Marks F
Effect of tumor promoting phorbol ester TPA on epidermal protein synthesis: stimulation of an elongation factor 2 phosphatase activity by TPA in vivo.
Biochemical and biophysical research communications 1988;153(3):1129-35.
1988: Gschwendt M; Fürstenberger G; Rose-John S; Rogers M; Kittstein W; Pettit G R; Herald C L; Marks F
Bryostatin 1, an activator of protein kinase C, mimics as well as inhibits biological effects of the phorbol ester TPA in vivo and in vitro.
Carcinogenesis 1988;9(4):555-62.
1988: Gschwendt M; Kittstein W; Marks F
The weak immunosuppressant cyclosporine D as well as the immunologically inactive cyclosporine H are potent inhibitors in vivo of phorbol ester TPA-induced biological effects in mouse skin and of Ca2+/calmodulin dependent EF-2 phosphorylation in vitro.
Biochemical and biophysical research communications 1988;150(2):545-51.
1988: Gschwendt M; Kittstein W; Marks F
Ciclosporin inhibits phorbol-ester-induced hyperplastic transformation and tumor promotion in mouse skin probably by suppression of Ca2+/calmodulin-dependent processes such as phosphorylation of elongation factor 2.
Skin pharmacology : the official journal of the Skin Pharmacology Society 1988;1(2):84-92.
1987: Gschwendt M; Kittstein W; Marks F
Didemnin B inhibits biological effects of tumor promoting phorbol esters on mouse skin, as well as phosphorylation of a 100 kD protein in mouse epidermis cytosol.
Cancer letters 1987;34(2):187-91.
1987: Gschwendt M; Kittstein W; Marks F
Cyclosporin A inhibits phorbol ester-induced cellular proliferation and tumor promotion as well as phosphorylation of a 100-kd protein in mouse epidermis.
Carcinogenesis 1987;8(2):203-7.
1986: Gschwendt M; Kittstein W; Marks F
A novel type of phorbol ester-dependent protein phosphorylation in the particulate fraction of mouse epidermis.
Biochemical and biophysical research communications 1986;137(2):766-74.
1986: Gschwendt M; Fürstenberger G; Kittstein W; Besemfelder E; Hull W E; Hagedorn H; Opferkuch H J; Marks F
Generation of the arachidonic acid metabolite 8-HETE by extracts of mouse skin treated with phorbol ester in vivo; identification by 1H-n.m.r. and GC-MS spectroscopy.
Carcinogenesis 1986;7(3):449-55.
1985: Gschwendt M; Kittstein W; Horn F; Marks F
Cyclosporin A inhibits biological effects of tumor promoting phorbol esters.
Biochemical and biophysical research communications 1985;126(1):327-32.
1984: Gschwendt M; Kittstein W; Fürstenberger G; Marks F
The mouse ear edema: a quantitatively evaluable assay for tumor promoting compounds and for inhibitors of tumor promotion.
Cancer letters 1984;25(2):177-85.
1984: Gschwendt M; Horn F; Kittstein W; Fürstenberger G; Besemfelder E; Marks F
Calcium and phospholipid-dependent protein kinase activity in mouse epidermis cytosol. Stimulation by complete and incomplete tumor promoters and inhibition by various compounds.
Biochemical and biophysical research communications 1984;124(1):63-8.
1984: Gschwendt M; Kittstein W; Marks F
Stimulation of alkaline phosphatase activity in mouse epidermis by tumor promoters.
Cancer letters 1984;22(2):219-25.
1983: Gschwendt M; Horn F; Kittstein W; Marks F
Inhibition of the calcium- and phospholipid-dependent protein kinase activity from mouse brain cytosol by quercetin.
Biochemical and biophysical research communications 1983;117(2):444-7.
1983: Gschwendt M; Horn F; Kittstein W; Fürstenberger G; Marks F
Soluble phorbol ester binding sites and phospholipid- and calcium-dependent protein kinase activity in cytosol of chick oviduct.
FEBS letters 1983;162(1):147-50.
1983: Gschwendt M; Kittstein W
Soluble phorbol ester binding sites in cytosol of chick liver and brain--activation by phosphatidylserine.
Cancer letters 1983;19(2):159-64.
1983: Gschwendt M; Rincke G; Schuster T
Inhibition of the estrogen-induced synthesis of vitellogenin mRNA in chick liver by tamoxifen.
Biochemical and biophysical research communications 1983;112(2):425-30.
1983: Gschwendt M; Kittstein W
Disactivation and inhibition of activation of the estrogen receptor from chick oviduct by periodate - comparison with the effects of molybdate and o-phenanthroline.
Journal of receptor research 1983;3(3):377-92.
1982: Gschwendt M; Rincke G; Schuster T
The estrogen-induced vitellogenin synthesis in chicken liver after estrogen withdrawal or antiestrogen treatment.
Molecular and cellular endocrinology 1982;26(1-2):231-42.
1980: Gschwendt M; Kittstein W
Transformation of the estrogen-receptor complex from chick oviduct in 2 steps.
Molecular and cellular endocrinology 1980;20(3):251-60.

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