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Lyle Armstrong

Research Profile

Physiology

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Publications

TOP 3
Chunbo Yang; Stuart P Atkinson; Felipe Vilella; Maria Lloret; Lyle Armstrong; Derek A Mann; Majlinda Lako
Opposing putative roles for canonical and noncanonical NFκB signaling on the survival, proliferation, and differentiation potential of human embryonic stem cells.
Anna Golebiewska; Stuart P Atkinson; Majlinda Lako; Lyle Armstrong
Epigenetic landscaping during hESC differentiation to neural cells.
T Maimets; I Neganova; Lyle Armstrong; Majlinda Lako
Activation of p53 by nutlin leads to rapid differentiation of human embryonic stem cells.

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All Publications

2010: Chunbo Yang; Stuart P Atkinson; Felipe Vilella; Maria Lloret; Lyle Armstrong; Derek A Mann; Majlinda Lako
Opposing putative roles for canonical and noncanonical NFκB signaling on the survival, proliferation, and differentiation potential of human embryonic stem cells.
Stem cells (Dayton, Ohio) 2010;28(11):1970-80.
2009: Anna Golebiewska; Stuart P Atkinson; Majlinda Lako; Lyle Armstrong
Epigenetic landscaping during hESC differentiation to neural cells.
Stem cells (Dayton, Ohio) 2009;27(6):1298-308.
2008: T Maimets; I Neganova; Lyle Armstrong; Majlinda Lako
Activation of p53 by nutlin leads to rapid differentiation of human embryonic stem cells.
Oncogene 2008;27(40):5277-87.
2008: Maria H Ledran; Anna Krassowska; Lyle Armstrong; Ian Dimmick; Jonas Renström; Roland Lang; Sun Yung; Mauro Santibanez-Coref; Elaine Dzierzak; Miodrag Stojkovic; Robert Oostendorp; Lesley Forrester; Majlinda Lako
Efficient hematopoietic differentiation of human embryonic stem cells on stromal cells derived from hematopoietic niches.
Cell stem cell 2008;3(1):85-98.
2008: Rebecca Stewart; Chunbo Yang; George Anyfantis; Stefan Przyborski; Nicholas Hole; Tom Strachan; Miodrag Stojkovic; Nicol Keith; Lyle Armstrong; Majlinda Lako
Silencing of the expression of pluripotent driven-reporter genes stably transfected into human pluripotent cells.
Regenerative medicine 2008;3(4):505-22.
2008: Sajjad Ahmad; Sai Kolli; De-Quan Li; Cintia S De Paiva; Stefan Pryzborski; Ian Dimmick; Lyle Armstrong; Francisco C Figueiredo; Majlinda Lako
A putative role for RHAMM/HMMR as a negative marker of stem cell-containing population of human limbal epithelial cells.
Stem cells (Dayton, Ohio) 2008;26(6):1609-19.
2008: Stuart P Atkinson; Christoph M Koch; Gayle K Clelland; Sarah Willcox; Joanna C Fowler; Rebecca Stewart; Majlinda Lako; Ian Dunham; Lyle Armstrong
Epigenetic marking prepares the human HOXA cluster for activation during differentiation of pluripotent cells.
Stem cells (Dayton, Ohio) 2008;26(5):1174-85.
2008: Chunbo Yang; Stefan Przyborski; Michael J Cooke; Xin Zhang; Rebecca Stewart; George Anyfantis; Stuart P Atkinson; Gabriele Saretzki; Lyle Armstrong; Majlinda Lako
A key role for telomerase reverse transcriptase unit in modulating human embryonic stem cell proliferation, cell cycle dynamics, and in vitro differentiation.
Stem cells (Dayton, Ohio) 2008;26(4):850-63.
2007: Sajjad Ahmad; Rebecca Stewart; Sun Yung; Sai Kolli; Lyle Armstrong; Miodrag Stojkovic; Francisco C Figueiredo; Majlinda Lako
Differentiation of human embryonic stem cells into corneal epithelial-like cells by in vitro replication of the corneal epithelial stem cell niche.
Stem cells (Dayton, Ohio) 2007;25(5):1145-55.
2006: Xin Zhang; Petra Stojkovic; Stefan Przyborski; Michael Cooke; Lyle Armstrong; Majlinda Lako; Miodrag Stojkovic
Derivation of human embryonic stem cells from developing and arrested embryos.
Stem cells (Dayton, Ohio) 2006;24(12):2669-76.
2006: Lyle Armstrong; Owen Hughes; Sun Yung; Louise Hyslop; Rebecca Stewart; Ilka Wappler; Heiko Peters; Theresia Walter; Petra Stojkovic; Jerome Evans; Miodrag Stojkovic; Majlinda Lako
The role of PI3K/AKT, MAPK/ERK and NFkappabeta signalling in the maintenance of human embryonic stem cell pluripotency and viability highlighted by transcriptional profiling and functional analysis.
Human molecular genetics 2006;15(11):1894-913.
2006: Lyle Armstrong; Majlinda Lako; Wendy Dean; Miodrag Stojkovic
Epigenetic modification is central to genome reprogramming in somatic cell nuclear transfer.
Stem cells (Dayton, Ohio) 2006;24(4):805-14.
2005: Louise Hyslop; Lyle Armstrong; Miodrag Stojkovic; Majlinda Lako
Human embryonic stem cells: biology and clinical implications.
Expert reviews in molecular medicine 2005;7(19):1-21.
2005: Louise Hyslop; Miodrag Stojkovic; Lyle Armstrong; Theresia Walter; Petra Stojkovic; Stefan Przyborski; Mary Herbert; Alison Murdoch; Tom Strachan; Majlinda Lako
Downregulation of NANOG induces differentiation of human embryonic stem cells to extraembryonic lineages.
Stem cells (Dayton, Ohio) 2005;23(8):1035-43.
2005: Miodrag Stojkovic; Petra Stojkovic; Christine Leary; Vanessa J Hall; Lyle Armstrong; Mary Herbert; Maria Nesbitt; Majlinda Lako; Alison Murdoch
Derivation of a human blastocyst after heterologous nuclear transfer to donated oocytes.
Reproductive biomedicine online 2005;11(2):226-31.
2005: Petra Stojkovic; Majlinda Lako; Stefan Przyborski; Rebecca Stewart; Lyle Armstrong; Jerome Evans; Xin Zhang; Miodrag Stojkovic
Human-serum matrix supports undifferentiated growth of human embryonic stem cells.
Stem cells (Dayton, Ohio) 2005;23(7):895-902.
2005: Lyle Armstrong; Gabriele Saretzki; Heiko Peters; Ilka Wappler; Jerome Evans; Nicholas Hole; Thomas von Zglinicki; Majlinda Lako
Overexpression of telomerase confers growth advantage, stress resistance, and enhanced differentiation of ESCs toward the hematopoietic lineage.
Stem cells (Dayton, Ohio) 2005;23(4):516-29.
2005: Petra Stojkovic; Majlinda Lako; Rebecca Stewart; Stefan Przyborski; Lyle Armstrong; Jerome Evans; Alison Murdoch; Tom Strachan; Miodrag Stojkovic
An autogeneic feeder cell system that efficiently supports growth of undifferentiated human embryonic stem cells.
Stem cells (Dayton, Ohio) 2005;23(3):306-14.
2004: Lyle Armstrong; Majlinda Lako; Ine van Herpe; Jerry Evans; Gabriele Saretzki; Nicholas Hole
A role for nucleoprotein Zap3 in the reduction of telomerase activity during embryonic stem cell differentiation.
Mechanisms of development 2004;121(12):1509-22.
2004: Lyle Armstrong; Miodrag Stojkovic; Ian Dimmick; Sajjad Ahmad; Petra Stojkovic; Nicholas Hole; Majlinda Lako
Phenotypic characterization of murine primitive hematopoietic progenitor cells isolated on basis of aldehyde dehydrogenase activity.
Stem cells (Dayton, Ohio) 2004;22(7):1142-51.
2004: Gabriele Saretzki; Lyle Armstrong; Alan Leake; Majlinda Lako; Thomas von Zglinicki
Stress defense in murine embryonic stem cells is superior to that of various differentiated murine cells.
Stem cells (Dayton, Ohio) 2004;22(6):962-71.
2004: Miodrag Stojkovic; Majlinda Lako; Petra Stojkovic; Rebecca Stewart; Stefan Przyborski; Lyle Armstrong; Jerry Evans; Mary Herbert; Louise Hyslop; Sajjad Ahmad; Alison Murdoch; Tom Strachan
Derivation of human embryonic stem cells from day-8 blastocysts recovered after three-step in vitro culture.
Stem cells (Dayton, Ohio) 2004;22(5):790-7.
2002: Majlinda Lako; Lyle Armstrong; Paul M Cairns; Sue Harris; Nicholas Hole; Colin A B Jahoda
Hair follicle dermal cells repopulate the mouse haematopoietic system.
Journal of cell science 2002;115(Pt 20):3967-74.
2001: Majlinda Lako; S Lindsay; Joy Lincoln; Paul M Cairns; Lyle Armstrong; Nicholas Hole
Characterisation of Wnt gene expression during the differentiation of murine embryonic stem cells in vitro: role of Wnt3 in enhancing haematopoietic differentiation.
Mechanisms of development 2001;103(1-2):49-59.
2000: Lyle Armstrong; Majlinda Lako; Joy Lincoln; Paul M Cairns; Nicholas Hole
mTert expression correlates with telomerase activity during the differentiation of murine embryonic stem cells.
Mechanisms of development 2000;97(1-2):109-16.