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Xin-Yuan Guan

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Ying-Hui Zhu; Leilei Chen; Yongdong Dai; Sui-Sui Dong; Li Fu; Jiangchao Li; Yan Li; Haibo Liu; Yan-Ru Qin; Dan Xie; Fajun Xie; Tingting Zeng; Xin-Yuan Guan
Downregulation of the novel tumor suppressor DIRAS1 predicts poor prognosis in esophageal squamous cell carcinoma.
Leilei Chen; Raymond Kwok Kei Chow; Li Fu; Tim Hon Man Chan; Kar Lok Kong; Dora Lai-Wan Kwong; Yan Li; Yan Li; Chi Ho Lin; Ming Liu; Chung-Mau Lo; Si Lok; Kwan Man; Lihua Qi; Yangyang Song; Daniel G Tenen; Amy Hin Yan Tong; Yun-Fei Yuan; Na Zhang; Xin-Yuan Guan
Recoding RNA editing of AZIN1 predisposes to hepatocellular carcinoma.
Li-Yi Zhang; Ying-Hui Zhu; Juan Chen; Sui-Sui Dong; Xin-Yuan Guan; Victor Ho-Fun Lee; Kar-Lok Kong; Dora Lai-Wan Kwong; Sai Wah Tsao; Alissa Michelle Go Wong; Li Fu
MicroRNA-144 promotes cell proliferation, migration and invasion in nasopharyngeal carcinoma through repression of PTEN.

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All Publications

2013: Ying-Hui Zhu; Leilei Chen; Yongdong Dai; Sui-Sui Dong; Li Fu; Jiangchao Li; Yan Li; Haibo Liu; Yan-Ru Qin; Dan Xie; Fajun Xie; Tingting Zeng; Xin-Yuan Guan
Downregulation of the novel tumor suppressor DIRAS1 predicts poor prognosis in esophageal squamous cell carcinoma.
Cancer research 2013;73(7):2298-309.
2013: Leilei Chen; Raymond Kwok Kei Chow; Li Fu; Tim Hon Man Chan; Kar Lok Kong; Dora Lai-Wan Kwong; Yan Li; Yan Li; Chi Ho Lin; Ming Liu; Chung-Mau Lo; Si Lok; Kwan Man; Lihua Qi; Yangyang Song; Daniel G Tenen; Amy Hin Yan Tong; Yun-Fei Yuan; Na Zhang; Xin-Yuan Guan
Recoding RNA editing of AZIN1 predisposes to hepatocellular carcinoma.
Nature medicine 2013;19(2):209-16.
2013: Li-Yi Zhang; Ying-Hui Zhu; Juan Chen; Sui-Sui Dong; Xin-Yuan Guan; Victor Ho-Fun Lee; Kar-Lok Kong; Dora Lai-Wan Kwong; Sai Wah Tsao; Alissa Michelle Go Wong; Li Fu
MicroRNA-144 promotes cell proliferation, migration and invasion in nasopharyngeal carcinoma through repression of PTEN.
Carcinogenesis 2013;34(2):454-63.
2013: Yan Li; Haibo Liu; Chang-Jun Nie; Yanru Qin; Ting-ting Zeng; Jie Zhou; Cai-Lei Zhu; J Chen; Kai Chen; Li Fu; Jiang-Chao Li; Xin-Yuan Guan
Investigation of tumor suppressing function of CACNA2D3 in esophageal squamous cell carcinoma.
PloS one 2013;8(4):e60027.
2013: Jiangchao Li; Xiaodong Li; Yan Li; Haibo Liu; Yanru Qin; Lijing Wang; Hong Yang; Li Fu; Xin-Yuan Guan
Cell-specific detection of miR-375 downregulation for predicting the prognosis of esophageal squamous cell carcinoma by miRNA in situ hybridization.
PloS one 2013;8(1):e53582.
2013: Yan Li; Ming Liu; Ji-Liang Qiu; Yun-Fei Yuan; Tim Hon Man Chan; Leilei Chen; Kar-Lok Kong; Yan Li; Xin-Yuan Guan
SPOCK1 is regulated by CHD1L and blocks apoptosis and promotes HCC cell invasiveness and metastasis in mice.
Gastroenterology 2013;144(1):179-191.e4.
2012: Man Tong; Kai-Yau Wong; Yan-Ru Qin; Kwan Ho Tang; Jessie Y J Bao; Kwok Wah Chan; Jin-Na Chen; Li Fu; Xin-Yuan Guan; Pak Shing Kwan; Si Lok; Stephanie Ma
Rab25 is a tumor suppressor gene with antiangiogenic and anti-invasive activities in esophageal squamous cell carcinoma.
Cancer research 2012;72(22):6024-35.
2012: Stephanie Ma; Yan-Ru Qin; Amy Hin Yan Tong; Carol M Tong; Sai Wah Tsao; Na Zhang; Jessie Y J Bao; Kwok Wah Chan; Yuen-Piu Chan; Li Fu; Pak Shing Kwan; Si Lok; Xin-Yuan Guan
Identification of PTK6, via RNA sequencing analysis, as a suppressor of esophageal squamous cell carcinoma.
Gastroenterology 2012;143(3):675-86.e1-12.
2012: Liang Hu; Ke-Ke Huo; Ming Liu; Jian Wang; Dan Xie; Bo-Jian Zheng; Tim Hon Man Chan; Leilei Chen; Xin-Yuan Guan
SCYL1 binding protein 1 promotes the ubiquitin-dependent degradation of Pirh2 and has tumor-suppressive function in the development of hepatocellular carcinoma.
Carcinogenesis 2012;33(8):1581-8.
2012: Ming Liu; Jian Wang; Yun-Fei Yuan; Ting-Ting Zeng; Tim Hon Man Chan; Leilei Chen; Yan Li; Yan Li; Xin-Yuan Guan
Serum and glucocorticoid kinase 3 at 8q13.1 promotes cell proliferation and survival in hepatocellular carcinoma.
Hepatology (Baltimore, Md.) 2012;55(6):1754-65.
2012: Juan Chen; Li Fu; Dora L Kwong; Li Yan; Li-Yi Zhang; Xin-Yuan Guan
Tumor suppressor genes on frequently deleted chromosome 3p in nasopharyngeal carcinoma.
Chinese journal of cancer 2012;31(5):215-22.
2012: Wei Zhu; Yi-Xin Zeng; Xiu-wu Bian; Mu-Yan Cai; Sui-Sui Dong; Xin-Yuan Guan; Hsiang-Fu Kung; Yi-Ji Liao; Marie C Lin; Shi-Juan Mai; Zhu-Ting Tong; Dan Xie
Overexpression of EIF5A2 promotes colorectal carcinoma cell aggressiveness by upregulating MTA1 through C-myc to induce epithelial-mesenchymaltransition.
Gut 2012;61(4):562-75.
2012: Kwan Ho Tang; Ka-Fai To; Carol M Tong; Yuen-Piu Chan; Xin-Yuan Guan; Pak Shing Kwan; Paul B Lai; Terence K Lee; Chung-Mau Lo; Stephanie Ma; Kwan Man; Irene O Ng; Kwok Wah Chan
CD133(+) liver tumor-initiating cells promote tumor angiogenesis, growth, and self-renewal through neurotensin/interleukin-8/CXCL1 signaling.
Hepatology (Baltimore, Md.) 2012;55(3):807-20.
2012: Tim Hon Man Chan; Leilei Chen; Liang Hu; Jian-Dong Huang; Pinzhu Huang; Ming Liu; Vincent Kwok-Man Poon; George Sai-wah Tsao; Jie Yang; Yun-Fei Yuan; Bo-Jian Zheng; Xin-Yuan Guan
Translationally controlled tumor protein induces mitotic defects and chromosome missegregation in hepatocellular carcinoma development.
Hepatology (Baltimore, Md.) 2012;55(2):491-505.
2012: Alissa Michelle Go Wong; Kar Lok Kong; Dora Lai Wan Kwong; Janice Wing Hang Tsang; Xin-Yuan Guan
Profiling of Epstein-Barr virus-encoded microRNAs in nasopharyngeal carcinoma reveals potential biomarkers and oncomirs.
Cancer 2012;118(3):698-710.
2012: Zhi-Yu Wang; De-po Yang; Xin-Yuan Guan; Tjing Yung Loo; Sui-Lin Mo; Jian-Gang Shen; Dong-Mei Wang; Neng Wang; Jian-Ping Chen
LDH-A silencing suppresses breast cancer tumorigenicity through induction of oxidative stress mediated mitochondrial pathway apoptosis.
Breast cancer research and treatment 2012;131(3):791-800.
2012: Wen Deng; Xin-Yuan Guan; Sai Wah Tsao; Annie L M Cheung
Pericentromeric regions are refractory to prompt repair after replication stress-induced breakage in HPV16 E6E7-expressing epithelial cells.
PloS one 2012;7(10):e48576.
2012: Jian Li; John M Luk; Dan Xie; Yun-Fei Yuan; Leilei Chen; Jun Huang; George Lau; Xin-Yuan Guan
Interleukin 23 promotes hepatocellular carcinoma metastasis via NF-kappa B induced matrix metalloproteinase 9 expression.
PloS one 2012;7(9):e46264.
2012: Wei-Peng He; Hsiang-Fu Kung; Yi-Ji Liao; Xiang-Shen Xiao; Dan Xie; Mu-Yan Cai; Xin-Yuan Guan; Juan Zhou; Guo-Fen Yang
CHD1L protein is overexpressed in human ovarian carcinomas and is a novel predictive biomarker for patients survival.
BMC cancer 2012;12():437.
2012: Juan Chen; Lei-Lei Chen; Sui-Sui Dong; Li Fu; Ting-Ting Cao; Kar-Lok Kong; Dora Lai-Wan Kwong; Yan Li; Ming Liu; Chu-Bo Qi; Jun Tian; Alissa Michelle Go Wong; Li-Yi Zhang; Cai-Lei Zhu; Xin-Yuan Guan
RBMS3 at 3p24 inhibits nasopharyngeal carcinoma development via inhibiting cell proliferation, angiogenesis, and inducing apoptosis.
PloS one 2012;7(9):e44636.
2012: Tim Hon Man Chan; Leilei Chen; Xin-Yuan Guan
Role of translationally controlled tumor protein in cancer progression.
Biochemistry research international 2012;2012():369384.
2012: Jiangchao Li; Xiaodong Li; Yan Li; Lulu Liu; Xueying Mao; Hong Yang; Tingting Zeng; Yinghui Zhu; Jiaoyu Ai; Kai Chen; Leilei Chen; Yongdong Dai; Xin-Yuan Guan
Establishment and characterization of human non-small cell lung cancer cell lines.
Molecular medicine reports 2012;5(1):114-7.
2012: Song Lu; Mai Har Sham; Qiu-Ju Yuan; Xin-Yuan Guan; Meng-Fei Liu; Lin-Yu Lu; Jian-Dong Huang
Cerebellar defects in Pdss2 conditional knockout mice during embryonic development and in adulthood.
Neurobiology of disease 2012;45(1):219-33.
2012: Kar Lok Kong; Dora Lai Wan Kwong; Simon Ying-Kit Law; Yan Li; Yan-Ru Qin; Tim Hon-Man Chan; Leilei Chen; Xin-Yuan Guan
MicroRNA-375 inhibits tumour growth and metastasis in oesophageal squamous cell carcinoma through repressing insulin-like growth factor 1 receptor.
Gut 2012;61(1):33-42.
2011: Li Fu; Juan Chen; Yongdong Dai; Sui-Sui Dong; Kar Lok Kong; Dora L Kwong; Yan Li; Lu-Hui Lu; Chunyu Zhang; Li-Yi Zhang; Xin-Yuan Guan
Wnt2 secreted by tumour fibroblasts promotes tumour progression in oesophageal cancer by activation of the Wnt/β-catenin signalling pathway.
Gut 2011;60(12):1635-43.
2011: Yan Li; Haibo Liu; Xueying Mao; Chang-jun Nie; Yanru Qin; Ting-ting Zeng; Ying-Hui Zhu; Leilei Chen; Li Fu; Xin-Yuan Guan
Downregulation of RBMS3 is associated with poor prognosis in esophageal squamous cell carcinoma.
Cancer research 2011;71(19):6106-15.
2011: Xiang-Sheng Xiao; Yi-Xin Zeng; Mu-Yan Cai; Jie-Wei Chen; Xin-Yuan Guan; Hsiang-Fu Kung; Dan Xie
High Expression of p300 in Human Breast Cancer Correlates with Tumor Recurrence and Predicts Adverse Prognosis.
Chinese journal of cancer research = Chung-kuo yen cheng yen chiu 2011;23(3):201-7.
2011: Carol Man Tong; Stephanie Ma; Xin-Yuan Guan
Biology of hepatic cancer stem cells.
Journal of gastroenterology and hepatology 2011;26(8):1229-37.
2011: Mu-Yan Cai; Yang-Chao Chen; Xin-Yuan Guan; Hsiang-Fu Kung; Yi-Ji Liao; Marie C Lin; Yan-Hui Liu; Hui-lan Rao; Zhu-Ting Tong; Yi Wang; Qiu-Liang Wu; Yi-Xin Zeng; Fang Zheng; Dan Xie
EZH2 protein: a promising immunomarker for the detection of hepatocellular carcinomas in liver needle biopsies.
Gut 2011;60(7):967-76.
2011: Li-Ru He; Hong-Yun Zhao; Bin-Kui Li; Yan-Hui Liu; Meng-Zhong Liu; Xin-Yuan Guan; Xiu-wu Bian; Yi-Xin Zeng; Dan Xie
Overexpression of eIF5A-2 is an adverse prognostic marker of survival in stage I non-small cell lung cancer patients.
International journal of cancer. Journal international du cancer 2011;129(1):143-50.
2011: Leilei Chen; Yun-Fei Yuan; Yan Li; Tim Hon Man Chan; Bo-Jian Zheng; Jun Huang; Xin-Yuan Guan
Clinical significance of CHD1L in hepatocellular carcinoma and therapeutic potentials of virus-mediated CHD1L depletion.
Gut 2011;60(4):534-43.
2011: Wen Deng; Sai Wah Tsao; G W Y Mak; C M Tsang; Yick-Pang Ching; Xin-Yuan Guan; Michael S Y Huen; Annie L M Cheung
Impact of G₂ checkpoint defect on centromeric instability.
Oncogene 2011;30(11):1281-9.
2011: Stephanie Ma; Xin-Yuan Guan
MiRegulators in cancer stem cells of solid tumors.
Cell cycle (Georgetown, Tex.) 2011;10(4):571-2.
2011: Zhi-Yu Wang; Dong-Mei Wang; Tjing Yung Loo; Yue Cheng; Lei-Lei Chen; Jian-Gang Shen; De-po Yang; Louis Wing-Cheong Chow; Xin-Yuan Guan; Jian-Ping Chen
Spatholobus suberectus inhibits cancer cell growth by inducing apoptosis and arresting cell cycle at G2/M checkpoint.
Journal of ethnopharmacology 2011;133(2):751-8.
2011: Stephanie Ma; Yuen-Piu Chan; Pak Shing Kwan; Terence K Lee; Mingxia Yan; Kwan Ho Tang; Ming-Tat Ling; Juergen Vielkind; Xin-Yuan Guan; Kwok Wah Chan
MicroRNA-616 induces androgen-independent growth of prostate cancer cells by suppressing expression of tissue factor pathway inhibitor TFPI-2.
Cancer research 2011;71(2):583-92.
2011: Jian Wang; Yan Li; Leilei Chen; Xin-Yuan Guan
Overexpression of cathepsin Z contributes to tumor metastasis by inducing epithelial-mesenchymal transition in hepatocellular carcinoma.
PloS one 2011;6(9):e24967.
2011: Mu-Yan Cai; Xin-Yuan Guan; Ling-Ling Kong; Hsiang-Fu Kung; Hui-lan Rao; Zhu-Ting Tong; Zhu-Zhi Wen; Yi-Xin Zeng; Wei Zhu; Dan Xie
H3K27me3 protein is a promising predictive biomarker of patients' survival and chemoradioresistance in human nasopharyngeal carcinoma.
Molecular medicine (Cambridge, Mass.) 2011;17(11-12):1137-45.
2011: Muhan Chen; Hong Kui Deng; Wen Deng; Suisui Dong; Jian-Dong Huang; Michael S Y Huen; Sze Lan Tsang; Tong Zan; Gui-Xia Zhu; Leilei Chen; Xin-Yuan Guan
Overexpression of eIF-5A2 in mice causes accelerated organismal aging by increasing chromosome instability.
BMC cancer 2011;11():199.
2011: Fajun Xie; Haibo Liu; Ying-Hui Zhu; Yan-Ru Qin; Yongdong Dai; Tingting Zeng; Leilei Chen; Changjun Nie; Hong Tang; Yan Li; Li Fu; Xin-Yuan Guan
Overexpression of GPR39 contributes to malignant development of human esophageal squamous cell carcinoma.
BMC cancer 2011;11():86.
2011: Yan Li; Li Fu; Alissa Michelle Go Wong; Yan-Hui Fan; Miao-Xin Li; Jin-Xin Bei; Wei-Hua Jia; Yi-Xin Zeng; Danny Chan; Kenneth M C Cheung; Pak Sham; Daniel Chua; Xin-Yuan Guan; You-Qiang Song
Identification of genes with allelic imbalance on 6p associated with nasopharyngeal carcinoma in southern Chinese.
PloS one 2011;6(1):e14562.
2011: Yan-Ru Qin; Hong Tang; Fajun Xie; Haibo Liu; Yinghui Zhu; Jiaoyu Ai; Leilei Chen; Yan Li; Dora L W Kwong; Li Fu; Xin-Yuan Guan
Characterization of tumor-suppressive function of SOX6 in human esophageal squamous cell carcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2011;17(1):46-55.
2011: Mu-Yan Cai; Jing-Hui Hou; Hui-lan Rao; Rong-Zhen Luo; Mei Li; Xiao-Qing Pei; Marie C Lin; Xin-Yuan Guan; Hsiang-Fu Kung; Yi-Xin Zeng; Dan Xie
High expression of H3K27me3 in human hepatocellular carcinomas correlates closely with vascular invasion and predicts worse prognosis in patients.
Molecular medicine (Cambridge, Mass.) 2011;17(1-2):12-20.
2010: Stephanie Ma; Kwan Ho Tang; Yuen-Piu Chan; Terence K Lee; Pak Shing Kwan; Antonia Castilho; Irene Ng; Kwan Man; Nathalie Wong; Ka-Fai To; Bo-Jian Zheng; Paul B S Lai; Chung-Mau Lo; Kwok Wah Chan; Xin-Yuan Guan
miR-130b Promotes CD133(+) liver tumor-initiating cell growth and self-renewal via tumor protein 53-induced nuclear protein 1.
Cell stem cell 2010;7(6):694-707.
2010: Kar Lok Kong; Dora L W Kwong; Li Fu; Tak Hang Chan; Leilei Chen; Haibo Liu; Yan Li; Ying-Hui Zhu; Jiong Bi; Yan-Ru Qin; Simon Ying-Kit Law; Xin-Yuan Guan
Characterization of a candidate tumor suppressor gene uroplakin 1A in esophageal squamous cell carcinoma.
Cancer research 2010;70(21):8832-41.
2010: Leilei Chen; Tim Hon Man Chan; Xin-Yuan Guan
Chromosome 1q21 amplification and oncogenes in hepatocellular carcinoma.
Acta pharmacologica Sinica 2010;31(9):1165-71.
2010: Zhi-Yue Rao; Mu-Yan Cai; Guo-Fen Yang; Li-Ru He; Shi-Juan Mai; Wen-Feng Hua; Yi-Ji Liao; Hai-Xia Deng; Yang-Chao Chen; Xin-Yuan Guan; Yi-Xin Zeng; Hsiang-Fu Kung; Dan Xie
EZH2 supports ovarian carcinoma cell invasion and/or metastasis via regulation of TGF-beta1 and is a predictor of outcome in ovarian carcinoma patients.
Carcinogenesis 2010;31(9):1576-83.
2010: Jian-cong Sun; Ke Pan; Min-Shan Chen; Qi-Jing Wang; Hui Wang; Hai-qing Ma; Yong-Qiang Li; Xiao-ting Liang; Jian-jun Li; Jing-jing Zhao; Yi-bing Chen; Xiong-hao Pang; Wang-li Liu; Yun Cao; Xin-Yuan Guan; Qi-zhou Lian; Jian-Chuan Xia
Dendritic cells-mediated CTLs targeting hepatocellular carcinoma stem cells.
Cancer biology & therapy 2010;10(4):368-75.
2010: Nikki P Lee; Felice H Tsang; Felix H Shek; Mao Mao; Hongyue Dai; Chunsheng Zhang; Suisui Dong; Xin-Yuan Guan; Ronnie T P Poon; John Luk
Prognostic significance and therapeutic potential of eukaryotic translation initiation factor 5A (eIF5A) in hepatocellular carcinoma.
International journal of cancer. Journal international du cancer 2010;127(4):968-76.
2010: Li-Rong He; H-Y Zhao; Bin-Kui Li; Lan-Jun Zhang; Meng-Zhong Liu; Hsiang-Fu Kung; Xin-Yuan Guan; Xiu-wu Bian; Yi-Xin Zeng; Dan Xie
Overexpression of AIB1 negatively affects survival of surgically resected non-small-cell lung cancer patients.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2010;21(8):1675-81.
2010: Yan Li; Chang-Jun Nie; Liang Hu; Yanru Qin; Hai-Bo Liu; Ting-Ting Zeng; Leilei Chen; Li Fu; Wen Deng; Shu-Peng Chen; Wei-Hua Jia; Chunyu Zhang; Dan Xie; Xin-Yuan Guan
Characterization of a novel mechanism of genomic instability involving the SEI1/SET/NM23H1 pathway in esophageal cancers.
Cancer research 2010;70(14):5695-705.
2010: Li-Ru He; Meng-Zhong Liu; Bin-Kui Li; Wei-Hua Jia; Ying Zhang; Yi-Ji Liao; Yang-Chao Chen; Lan-Jun Zhang; Xin-Yuan Guan; Yi-Xin Zeng; Hsiang-Fu Kung; Dan Xie
High expression of EZH2 is associated with tumor aggressiveness and poor prognosis in patients with esophageal squamous cell carcinoma treated with definitive chemoradiotherapy.
International journal of cancer. Journal international du cancer 2010;127(1):138-47.
2010: Yi Wang; Yan-Hui Liu; Shi-Juan Mai; Long-Jun He; Yi-Ji Liao; Hai-Xia Deng; Xin-Yuan Guan; Yi-Xin Zeng; Hsiang-Fu Kung; Dan Xie
Evaluation of serum clusterin as a surveillance tool for human hepatocellular carcinoma with hepatitis B virus related cirrhosis.
Journal of gastroenterology and hepatology 2010;25(6):1123-8.
2010: Mu-Yan Cai; Bin Zhang; Wei-Peng He; Guo-Fen Yang; Hui-lan Rao; Zhi-Yue Rao; Qiu-Liang Wu; Xin-Yuan Guan; Hsiang-Fu Kung; Yi-Xin Zeng; Dan Xie
Decreased expression of PinX1 protein is correlated with tumor development and is a new independent poor prognostic factor in ovarian carcinoma.
Cancer science 2010;101(6):1543-9.
2010: Li Fu; Sui-Sui Dong; Yi-Wu Xie; Lai-Shan Tai; Leilei Chen; Kar Lok Kong; Kwan Man; Dan Xie; Yan Li; Yingduan Cheng; Qian Tao; Xin-Yuan Guan
Down-regulation of tyrosine aminotransferase at a frequently deleted region 16q22 contributes to the pathogenesis of hepatocellular carcinoma.
Hepatology (Baltimore, Md.) 2010;51(5):1624-34.
2010: Dong-Jiang Tang; Sui-Sui Dong; Ning-Fang Ma; Dan Xie; Leilei Chen; Li Fu; Sze Hang Lau; Yan Li; Yan Li; Xin-Yuan Guan
Overexpression of eukaryotic initiation factor 5A2 enhances cell motility and promotes tumor metastasis in hepatocellular carcinoma.
Hepatology (Baltimore, Md.) 2010;51(4):1255-63.
2010: Jing Wen; Bin Zheng; Yi Hu; Xu Zhang; Hong Yang; Yan Li; Chun-Yu Zhang; Kong-Jia Luo; Xing Zang; Yong-Feng Li; Xin-Yuan Guan; Jian-Hua Fu
Comparative proteomic analysis of the esophageal squamous carcinoma cell line EC109 and its multi-drug resistant subline EC109/CDDP.
International journal of oncology 2010;36(1):265-74.
2009: Li-Ru He; Meng-Zhong Liu; Bin-Kui Li; Hui-lan Rao; Yi-Ji Liao; Lan-Jun Zhang; Xin-Yuan Guan; Yi-Xin Zeng; Dan Xie
Clusterin as a predictor for chemoradiotherapy sensitivity and patient survival in esophageal squamous cell carcinoma.
Cancer science 2009;100(12):2354-60.
2009: Jiong Bi; Sze Hang Lau; Zi-Li Lv; Dan Xie; Wen Li; Ying-Rong Lai; Jue-Min Zhong; Hui-qun Wu; Qiao Su; Yu-long He; Wen-hua Zhan; Jian-ming Wen; Xin-Yuan Guan
Overexpression of YKL-40 is an independent prognostic marker in gastric cancer.
Human pathology 2009;40(12):1790-7.
2009: Guo-Qing Wu; Dan Xie; Guo-Feng Yang; Yi-Ji Liao; Shi-Juan Mai; Hai-Xia Deng; Johnny Sze; Xin-Yuan Guan; Yi-Xin Zeng; Marie C Lin; Hsiang-Fu Kung
Cell cycle-related kinase supports ovarian carcinoma cell proliferation via regulation of cyclin D1 and is a predictor of outcome in patients with ovarian carcinoma.
International journal of cancer. Journal international du cancer 2009;125(11):2631-42.
2009: C Zhu; Yan-Ru Qin; Dan Xie; D T T Chua; J M Fung; L Chen; Li Fu; Liang Hu; Xin-Yuan Guan
Characterization of tumor suppressive function of P300/CBP-associated factor at frequently deleted region 3p24 in esophageal squamous cell carcinoma.
Oncogene 2009;28(31):2821-8.
2009: Jie Zhou; Jian-Dong Huang; Vincent K M Poon; Ding-Qiang Chen; Chris C S Chan; Fai Ng; Xin-Yuan Guan; Rory Munro Watt; Liwei Lu; Kwok-Yung Yuen; Bo-Jian Zheng
Functional dissection of an IFN-alpha/beta receptor 1 promoter variant that confers higher risk to chronic hepatitis B virus infection.
Journal of hepatology 2009;51(2):322-32.
2009: Leilei Chen; Liang Hu; Tak Hang Chan; George S W Tsao; Dan Xie; Ke-Ke Huo; Li Fu; Stephanie Ma; Bo-Jian Zheng; Xin-Yuan Guan
Chromodomain helicase/adenosine triphosphatase DNA binding protein 1-like (CHD1l) gene suppresses the nucleus-to-mitochondria translocation of nur77 to sustain hepatocellular carcinoma cell survival.
Hepatology (Baltimore, Md.) 2009;50(1):122-9.
2009: Chunyu Zhang; Li Fu; Jianhua Fu; Liang Hu; Hong Yang; Tie-Hua Rong; Yan Li; Haibo Liu; Song-Bin Fu; Yi-Xin Zeng; Xin-Yuan Guan
Fibroblast growth factor receptor 2-positive fibroblasts provide a suitable microenvironment for tumor development and progression in esophageal carcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2009;15(12):4017-27.
2009: Betty H Y Chow; Daniel T T Chua; Jonathan S T Sham; Min-Yue Zhang; Louis W C Chow; Jiong Bi; Ning-Fang Ma; Dan Xie; Wings T Y Loo; Jackie M W Fung; Li Fu; Xin-Yuan Guan
Increased expression of annexin I is associated with drug-resistance in nasopharyngeal carcinoma and other solid tumors.
Proteomics. Clinical applications 2009;3(6):654-62.
2009: Stephanie Ma; Yuen-Piu Chan; Bruce Woolcock; Liang Hu; Kai-Yau Wong; Ming-Tat Ling; Terry Bainbridge; Douglas Webber; Tim Hon Man Chan; Xin-Yuan Guan; Wan Lam; Juergen Vielkind; Kwok Wah Chan
DNA fingerprinting tags novel altered chromosomal regions and identifies the involvement of SOX5 in the progression of prostate cancer.
International journal of cancer. Journal international du cancer 2009;124(10):2323-32.
2009: Jun-Hang Luo; Wen-Feng Hua; Hui-Lan Rao; Yi-Ji Liao; Hsiang-Fu Kung; Yi-Xin Zeng; Xin-Yuan Guan; Wei Chen; Dan Xie
Overexpression of EIF-5A2 predicts tumor recurrence and progression in pTa/pT1 urothelial carcinoma of the bladder.
Cancer science 2009;100(5):896-902.
2009: Jiong Bi; Sze Hang Lau; Liang Hu; Hui-Lan Rao; Hai-Bo Liu; Wen-hua Zhan; Gong Chen; Jian-ming Wen; Qian Wang; Bin Li; Xin-Yuan Guan
Downregulation of ZIP kinase is associated with tumor invasion, metastasis and poor prognosis in gastric cancer.
International journal of cancer. Journal international du cancer 2009;124(7):1587-93.
2009: Jackie Mei-Wah Fung; Ross Smith; Melissa A Brown; Sze Hang Lau; Dan Xie; George K K Lau; Xin-Yuan Guan
Identification and characterization of a novel melanoma tumor suppressor gene on human chromosome 6q21.
Clinical cancer research : an official journal of the American Association for Cancer Research 2009;15(3):797-803.
2009: Wei Chen; Jun-Hang Luo; Wen-Feng Hua; Fang-Jian Zhou; Marie C Lin; Hsiang-Fu Kung; Yi-Xin Zeng; Xin-Yuan Guan; Dan Xie
Overexpression of EIF-5A2 is an independent predictor of outcome in patients of urothelial carcinoma of the bladder treated with radical cystectomy.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2009;18(2):400-8.
2009: Guo-Fen Yang; Dan Xie; Ji-Hong Liu; Jun-Hang Luo; Li-Juan Li; Wen-Feng Hua; Hong-Mei Wu; Hsiang-Fu Kung; Yi-Xin Zeng; Xin-Yuan Guan
Expression and amplification of eIF-5A2 in human epithelial ovarian tumors and overexpression of EIF-5A2 is a new independent predictor of outcome in patients with ovarian carcinoma.
Gynecologic oncology 2009;112(2):314-8.
2009: Li-Ru He; Meng-Zhong Liu; Bin-Kui Li; Hui-lan Rao; Yi-Ji Liao; Xin-Yuan Guan; Yi-Xin Zeng; Dan Xie
Prognostic impact of H3K27me3 expression on locoregional progression after chemoradiotherapy in esophageal squamous cell carcinoma.
BMC cancer 2009;9():461.
2008: Wen Deng; Sai Wah Tsao; Yvonne K Kwok; Esther Wong; Xiao Ru Huang; Si Liu; Chi M Tsang; Hextan Y S Ngan; Annie N Y Cheung; Hui Yao Lan; Xin-Yuan Guan; Annie L M Cheung
Transforming growth factor beta1 promotes chromosomal instability in human papillomavirus 16 E6E7-infected cervical epithelial cells.
Cancer research 2008;68(17):7200-9.
2008: Stephanie Ma; Kwok Wah Chan; Xin-Yuan Guan
In search of liver cancer stem cells.
Stem cell reviews 2008;4(3):179-92.
2008: Ning-Fang Ma; Sze Hang Lau; Liang Hu; Dan Xie; Jun Wu; Jun Yang; Yi Wang; Meng-Chao Wu; Jackie Fung; Xueyan Bai; Chi-Hung Tzang; Li Fu; Mengsu Yang; Yan An Su; Xin-Yuan Guan
COOH-terminal truncated HBV X protein plays key role in hepatocarcinogenesis.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(16):5061-8.
2008: Yan Ru Qin; Li Fu; Pak C Sham; Dora L W Kwong; Cai Lei Zhu; Kevin K W Chu; Yan Li; Xin-Yuan Guan
Single-nucleotide polymorphism-mass array reveals commonly deleted regions at 3p22 and 3p14.2 associate with poor clinical outcome in esophageal squamous cell carcinoma.
International journal of cancer. Journal international du cancer 2008;123(4):826-30.
2008: Stephanie Ma; Kwok Wah Chan; Terence Kin-Wah Lee; Kwan Ho Tang; Jana Yim-Hung Wo; Bo-Jian Zheng; Xin-Yuan Guan
Aldehyde dehydrogenase discriminates the CD133 liver cancer stem cell populations.
Molecular cancer research : MCR 2008;6(7):1146-53.
2008: Jun-Hang Luo; Dan Xie; Meng-Zhong Liu; Wei Chen; Yong-Dong Liu; Guo-Qing Wu; Hsiang-Fu Kung; Yi-Xin Zeng; Xin-Yuan Guan
Protein expression and amplification of AIB1 in human urothelial carcinoma of the bladder and overexpression of AIB1 is a new independent prognostic marker of patient survival.
International journal of cancer. Journal international du cancer 2008;122(11):2554-61.
2008: Meng-Zhong Liu; Dan Xie; Shi-Juan Mai; Zhu-Ting Tong; Jian-Yong Shao; Yong-Shui Fu; Wen-Jie Xia; Hsian-Fu Kung; Xin-Yuan Guan; Yi-Xin Zeng
Overexpression of AIB1 in nasopharyngeal carcinomas correlates closely with advanced tumor stage.
American journal of clinical pathology 2008;129(5):728-34.
2008: Yan-Ru Qin; Li-Dong Wang; Zong-Min Fan; Dora Kwong; Xin-Yuan Guan
Comparative genomic hybridization analysis of genetic aberrations associated with development of esophageal squamous cell carcinoma in Henan, China.
World journal of gastroenterology : WJG 2008;14(12):1828-35.
2008: S Ma; Terence K Lee; B-J Zheng; Kwok Wah Chan; Xin-Yuan Guan
CD133+ HCC cancer stem cells confer chemoresistance by preferential expression of the Akt/PKB survival pathway.
Oncogene 2008;27(12):1749-58.
2008: Dan Xie; Ning-Fang Ma; Zhi-Zhong Pan; Hui-Xi Wu; Yong-Dong Liu; Guo-Qing Wu; Hsiang-Fu Kung; Xin-Yuan Guan
Overexpression of EIF-5A2 is associated with metastasis of human colorectal carcinoma.
Human pathology 2008;39(1):80-6.
2007: Li Fu; Yan-Ru Qin; Dan Xie; Hoi Yee Chow; Sai Ming Ngai; Dora L W Kwong; Yan Li; Xin-Yuan Guan
Identification of alpha-actinin 4 and 67 kDa laminin receptor as stage-specific markers in esophageal cancer via proteomic approaches.
Cancer 2007;110(12):2672-81.
2007: Li Fu; Yan-Ru Qin; Dan Xie; Liang Hu; Dora L W Kwong; Gopesh Srivastava; Sai Wah Tsao; Xin-Yuan Guan
Characterization of a novel tumor-suppressor gene PLC delta 1 at 3p22 in esophageal squamous cell carcinoma.
Cancer research 2007;67(22):10720-6.
2007: Stephanie Ma; Liang Hu; Xiao-Hui Huang; Liang-Qi Cao; Kwok Wah Chan; Qian Wang; Xin-Yuan Guan
Establishment and characterization of a human cholangiocarcinoma cell line.
Oncology reports 2007;18(5):1195-200.
2007: Leo C M Cheung; Johnny Cheuk On Tang; P Y Lee; Liang Hu; Xin-Yuan Guan; W K Tang; Gopesh Srivastava; John Wong; John Luk; Simon Law
Establishment and characterization of a new xenograft-derived human esophageal squamous cell carcinoma cell line HKESC-4 of Chinese origin.
Cancer genetics and cytogenetics 2007;178(1):17-25.
2007: Terence K Lee; Ronnie T P Poon; Jana Y Wo; Stephanie Ma; Xin-Yuan Guan; Jeffrey N Myers; Peter Altevogt; Anthony Po-Wing Yuen
Lupeol suppresses cisplatin-induced nuclear factor-kappaB activation in head and neck squamous cell carcinoma and inhibits local invasion and nodal metastasis in an orthotopic nude mouse model.
Cancer research 2007;67(18):8800-9.
2007: Terence K Lee; Ronnie T P Poon; Kwan Man; Xin-Yuan Guan; Stephanie Ma; Xiao Bing Liu; Jeffrey N Myers; Anthony Po-Wing Yuen
Fascin over-expression is associated with aggressiveness of oral squamous cell carcinoma.
Cancer letters 2007;254(2):308-15.
2007: Stephanie Ma; Xin-Yuan Guan; Terence K Lee; Kwok Wah Chan
Clinicopathological significance of missing in metastasis B expression in hepatocellular carcinoma.
Human pathology 2007;38(8):1201-6.
2007: Yue-Qiu Tan; Xiao-Man Chen; Liang Hu; Xin-Yuan Guan; Guang-Xiu Lu
Prenatal diagnosis of nonmosaic tetrasomy 9p by microdissection and FISH: case report.
Chinese medical journal 2007;120(14):1281-3.
2007: Liang Hu; Jonathan S T Sham; Dan Xie; Jian-ming Wen; Wei-Sheng Wang; Yi Wang; Xin-Yuan Guan
Up-regulation of fibroblast growth factor 3 is associated with tumor metastasis and recurrence in human hepatocellular carcinoma.
Cancer letters 2007;252(1):36-42.
2007: Stephanie Ma; Kwok Wah Chan; Liang Hu; Terence K Lee; Jana Yim-Hung Wo; Irene Oi-Lin Ng; Bo-Jian Zheng; Xin-Yuan Guan
Identification and characterization of tumorigenic liver cancer stem/progenitor cells.
Gastroenterology 2007;132(7):2542-56.
2007: Wai Mui Tjia; Liang Hu; Min-Yue Zhang; Xin-Yuan Guan
Characterization of rearrangements involving 4q, 13q and 16q in hepatocellular carcinoma cell lines using region-specific multiplex-FISH probes.
Cancer letters 2007;250(1):92-9.
2007: Zheng Zhang; Dan Xie; Xin Li; Yong-Chuan Wong; Dian-qi Xin; Xin-Yuan Guan; Chee Wai Chua; Steve C L Leung; Yanqun Na; Xianghong Wang
Significance of TWIST expression and its association with E-cadherin in bladder cancer.
Human pathology 2007;38(4):598-606.
2007: S Ma; Xin-Yuan Guan; P S L Beh; K Y Wong; Yuen-Piu Chan; Hiu-Fung Yuen; J Vielkind; Kwok Wah Chan
The significance of LMO2 expression in the progression of prostate cancer.
The Journal of pathology 2007;211(3):278-85.
2007: Fang-Ping Xu; Dan Xie; Jian-ming Wen; Hui-Xi Wu; Yong-Dong Liu; Jiong Bi; Zili Lv; Yi-Xin Zeng; Xin-Yuan Guan
SRC-3/AIB1 protein and gene amplification levels in human esophageal squamous cell carcinomas.
Cancer letters 2007;245(1-2):69-74.
2006: Terence K Lee; Ronnie T P Poon; Anthony Po-Wing Yuen; Ming-Tat Ling; Xiang Hong Wang; Yong-Chuan Wong; Xin-Yuan Guan; Kwan Man; Zao You Tang; Sheung-Tat Fan
Regulation of angiogenesis by Id-1 through hypoxia-inducible factor-1alpha-mediated vascular endothelial growth factor up-regulation in hepatocellular carcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(23):6910-9.
2006: Terence K Lee; Ronnie T P Poon; Anthony Po-Wing Yuen; Ming-Tat Ling; Wai Kei Kwok; Xiang Hong Wang; Yong-Chuan Wong; Xin-Yuan Guan; Kwan Man; King Lok Chau; Sheung-Tat Fan
Twist overexpression correlates with hepatocellular carcinoma metastasis through induction of epithelial-mesenchymal transition.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(18):5369-76.
2006: Terence K Lee; Ronnie T P Poon; Anthony Po-Wing Yuen; Kwan Man; Zhen Fan Yang; Xin-Yuan Guan; Sheung-Tat Fan
Rac activation is associated with hepatocellular carcinoma metastasis by up-regulation of vascular endothelial growth factor expression.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(17):5082-9.
2006: Hiu Wing Cheung; Abel C S Chun; Qi Wang; Wen Deng; Liang Hu; Xin-Yuan Guan; John M Nicholls; Ming-Tat Ling; Yong Chuan Wong; Sai Wah Tsao; Dong-Yan Jin; Xianghong Wang
Inactivation of human MAD2B in nasopharyngeal carcinoma cells leads to chemosensitization to DNA-damaging agents.
Cancer research 2006;66(8):4357-67.
2006: Amy L S Tai; William Mak; Phoebe K M Ng; Daniel T T Chua; Mandy Y M Ng; Li Fu; Kevin K W Chu; Yan Fang; You Qiang Song; Muhan Chen; Minyue Zhang; Pak C Sham; Xin-Yuan Guan
High-throughput loss-of-heterozygosity study of chromosome 3p in lung cancer using single-nucleotide polymorphism markers.
Cancer research 2006;66(8):4133-8.
2006: Sze Hang Lau; Jonathan S T Sham; Dan Xie; C-H Tzang; D Tang; N Ma; Liang Hu; Yi Wang; Jian-ming Wen; G Xiao; W-M Zhang; George K K Lau; Mengsu Yang; Xin-Yuan Guan
Clusterin plays an important role in hepatocellular carcinoma metastasis.
Oncogene 2006;25(8):1242-50.
2006: Li-Dong Wang; Yan-Ru Qin; Zong-Min Fan; Dora L W Kwong; Xin-Yuan Guan; George S W Tsao; J Sham; Ji-Lin Li; Xiao-Shan Feng
Comparative genomic hybridization: comparison between esophageal squamous cell carcinoma and gastric cardia adenocarcinoma from a high-incidence area for both cancers in Henan, northern China.
Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus / I.S.D.E 2006;19(6):459-67.
2006: Amy L S Tai; Jonathan S T Sham; Dan Xie; Yan Fang; Yi-Long Wu; Liang Hu; Wen Deng; George S W Tsao; Gui-Bin Qiao; Annie L M Cheung; Xin-Yuan Guan
Co-overexpression of fibroblast growth factor 3 and epidermal growth factor receptor is correlated with the development of nonsmall cell lung carcinoma.
Cancer 2006;106(1):146-55.
2005: Dan Xie; Yi Xin Zeng; Hai Jun Wang; Lai Shan Tai; Jian-ming Wen; Yu Tao; Ning Fang Ma; Liang Hu; Jonathan S T Sham; Xin-Yuan Guan
Amplification and overexpression of epidermal growth factor receptor gene in glioblastomas of Chinese patients correlates with patient's age but not with tumor's clinicopathological pathway.
Acta neuropathologica 2005;110(5):481-9.
2005: Yan-Ru Qin; Li-Dong Wang; Kwong Dora; Xin-Yuan Guan; Zhuang Zehao; Zong-Min Fan; Wen Deng; Shi-Hua Cao
[Genomic changes in primary lesion and lymph node metastases of esophageal squamous cell carcinoma].
Ai zheng = Aizheng = Chinese journal of cancer 2005;24(9):1048-53.
2005: Dong-Jiang Tang; Liang Hu; Dan Xie; Qiu-Liang Wu; Yan Fang; Yixin Zeng; Jonathan S T Sham; Xin-Yuan Guan
Oncogenic transformation by SEI-1 is associated with chromosomal instability.
Cancer research 2005;65(15):6504-8.
2005: Dan Xie; Jonathan S T Sham; Wei-Fen Zeng; Han-Liang Lin; Jiong Bi; Li-Hong Che; Liang Hu; Yi-Xin Zeng; Xin-Yuan Guan
Correlation of AIB1 overexpression with advanced clinical stage of human colorectal carcinoma.
Human pathology 2005;36(7):777-83.
2005: C M Chung; Cornelia Man; Yuesheng Jin; Charlotte Jin; Xin-Yuan Guan; Qi Wang; THOMAS WAN; Annie L M Cheung; Sai Wah Tsao
Amplification and overexpression of aurora kinase A (AURKA) in immortalized human ovarian epithelial (HOSE) cells.
Molecular carcinogenesis 2005;43(3):165-74.
2005: Dan Xie; Jonathan S T Sham; Wei-Fen Zeng; Li-Hong Che; Meng Zhang; Hui-Xi Wu; Han-Liang Lin; Jian-ming Wen; Sze Hang Lau; Liang Hu; Xin-Yuan Guan
Oncogenic role of clusterin overexpression in multistage colorectal tumorigenesis and progression.
World journal of gastroenterology : WJG 2005;11(21):3285-9.
2005: Wei-Ping Qian; Yue-Qiu Tan; Wai Mui Tjia; Dan Song; Xin-Yuan Guan; Guang-Xiu Lu
[Molecular cytogenetic analysis for a familial complex chromosomal rearrangement].
Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics 2005;22(3):302-4.
2005: Sze Hang Lau; Xin-Yuan Guan
Cytogenetic and molecular genetic alterations in hepatocellular carcinoma.
Acta pharmacologica Sinica 2005;26(6):659-65.
2005: Amy L S Tai; Yan Fang; Jonathan S T Sham; Wen Deng; Liang Hu; Dan Xie; George S W Tsao; Annie L M Cheung; Xin-Yuan Guan
Establishment and characterization of a human non-small cell lung cancer cell line.
Oncology reports 2005;13(6):1029-32.
2005: Wai Mui Tjia; Jonathan S T Sham; Liang Hu; Amy L S Tai; Xin-Yuan Guan
Characterization of 3p, 5p, and 3q in two nasopharyngeal carcinoma cell lines, using region-specific multiplex fluorescence in situ hybridization probes.
Cancer genetics and cytogenetics 2005;158(1):61-6.
2005: Yan-Ru Qin; Li-Dong Wang; Dora L W Kwong; Shan-Shan Gao; Xin-Yuan Guan; Zhuang Zehao; Zong-Min Fan; Wen Deng; Liang Hu
[Comparative genomic hybridization: the profile of chromosomal imbalances in esophageal squamous cell carcinoma].
Zhonghua bing li xue za zhi Chinese journal of pathology 2005;34(2):80-3.
2005: Dan Xie; Sze Hang Lau; Jonathan S T Sham; Qiu-Liang Wu; Yan Fang; Li-Zhi Liang; Li-Hong Che; Yi-Xin Zeng; Xin-Yuan Guan
Up-regulated expression of cytoplasmic clusterin in human ovarian carcinoma.
Cancer 2005;103(2):277-83.
2004: Wen Deng; Sai Wah Tsao; Xin-Yuan Guan; Joe N Lucas; Hua Xin Si; Cynthia S W Leung; Priscilla Mak; Li Dong Wang; Annie L M Cheung
Distinct profiles of critically short telomeres are a key determinant of different chromosome aberrations in immortalized human cells: whole-genome evidence from multiple cell lines.
Oncogene 2004;23(56):9090-101.
2004: Yan-Ru Qin; Li-Dong Wang; Dora L W Kwong; Xin-Yuan Guan; Zhuang Zehao; Zong-Min Fan; Ji-Ye An; George S W Tsao
[Comparative genomic hybridization of esophageal squamous cell carcinoma and gastric cardia adenocarcinoma in high-incidence region of esophageal carcinoma, Linzhou Henan].
Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics 2004;21(6):625-8.
2004: Kok-Lung Chan; Xin-Yuan Guan; Irene Oi-Lin Ng
High-throughput tissue microarray analysis of c-myc activation in chronic liver diseases and hepatocellular carcinoma.
Human pathology 2004;35(11):1324-31.
2004: Li Zhu; Louis W C Chow; Wings T Y Loo; Xin-Yuan Guan; Mazakazu Toi
Her2/neu expression predicts the response to antiaromatase neoadjuvant therapy in primary breast cancer: subgroup analysis from celecoxib antiaromatase neoadjuvant trial.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(14):4639-44.
2004: Xin-Yuan Guan; Jackie M-W Fung; Ning-Fang Ma; Sze Hang Lau; Lai Shan Tai; Dan Xie; Yu Zhang; Liang Hu; Qiu-Liang Wu; Yan Fang; Jonathan S T Sham
Oncogenic role of eIF-5A2 in the development of ovarian cancer.
Cancer research 2004;64(12):4197-200.
2004: Amy L S Tai; Wen-Sheng Yan; Yan Fang; Dan Xie; Jonathan S T Sham; Xin-Yuan Guan
Recurrent chromosomal imbalances in nonsmall cell lung carcinoma: the association between 1q amplification and tumor recurrence.
Cancer 2004;100(9):1918-27.
2004: Liang Hu; Jonathan S T Sham; Wai Mui Tjia; Yue-Qiu Tan; Guang-Xiu Lu; Xin-Yuan Guan
Generation of a complete set of human telomeric band painting probes by chromosome microdissection.
Genomics 2004;83(2):298-302.
2004: Yue-Qiu Tan; Liang Hu; Ge Lin; Jonathan S T Sham; Fei Gong; Xin-Yuan Guan; Guangxiu Lu
Genetic changes in human fetuses from spontaneous abortion after in vitro fertilization detected by comparative genomic hybridization.
Biology of reproduction 2004;70(2):495-9.
2004: Xianghong Wang; Ming-Tat Ling; Xin-Yuan Guan; Sai Wah Tsao; Hiu Wing Cheung; Davy Tak Lee; Yong-Chuan Wong
Identification of a novel function of TWIST, a bHLH protein, in the development of acquired taxol resistance in human cancer cells.
Oncogene 2004;23(2):474-82.
2004: Yi Wang; Sze Hang Lau; Jonathan S T Sham; Meng-Chao Wu; Tao Wang; Xin-Yuan Guan
Characterization of HBV integrants in 14 hepatocellular carcinomas: association of truncated X gene and hepatocellular carcinogenesis.
Oncogene 2004;23(1):142-8.
2004: Liang Hu; Sze Hang Lau; Chi-Hung Tzang; Jian-ming Wen; Weisheng Wang; Dan Xie; Minghui Huang; Yi Wang; Meng-Chao Wu; Jie-Fu Huang; Wei-Fen Zeng; Jonathan S T Sham; Mengsu Yang; Xin-Yuan Guan
Association of Vimentin overexpression and hepatocellular carcinoma metastasis.
Oncogene 2004;23(1):298-302.
2004: Liang Hu; Jian-ming Wen; Jonathan S T Sham; Weisheng Wang; Dan Xie; Wai Mui Tjia; Jie-Fu Huang; Meng Zhang; Wei-Fen Zeng; Xin-Yuan Guan
Establishment of cell lines from a primary hepatocellular carcinoma and its metastatis.
Cancer genetics and cytogenetics 2004;148(1):80-4.
2003: Dan Xie; Jonathan S T Sham; Wei-Fen Zeng; Han-Liang Lin; Li-Hong Che; Hui-Xi Wu; Jian-ming Wen; Yan Fang; Liang Hu; Xin-Yuan Guan
Heterogeneous expression and association of beta-catenin, p16 and c-myc in multistage colorectal tumorigenesis and progression detected by tissue microarray.
International journal of cancer. Journal international du cancer 2003;107(6):896-902.
2003: Qiao-Jie He; Wei-Fen Zeng; Jonathan S T Sham; Dan Xie; Xing-Wu Yang; Han-Liang Lin; Wen-Hua Zhan; Feng Lin; Sui-de Zeng; Daping Nie; Lin-Fei Ma; Chu-jun Li; Shen Lu; Xin-Yuan Guan
Recurrent genetic alterations in 26 colorectal carcinomas and 21 adenomas from Chinese patients.
Cancer genetics and cytogenetics 2003;144(2):112-8.
2003: Wen Deng; Sai Wah Tsao; Xin-Yuan Guan; Joe N Lucas; Annie L M Cheung
Role of short telomeres in inducing preferential chromosomal aberrations in human ovarian surface epithelial cells: A combined telomere quantitative fluorescence in situ hybridization and whole-chromosome painting study.
Genes, chromosomes & cancer 2003;37(1):92-7.
2003: Irene Oi-Lin Ng; Xin-Yuan Guan; Ronnie T P Poon; Sheung-Tat Fan; Joyce Man-Fong Lee
Determination of the molecular relationship between multiple tumour nodules in hepatocellular carcinoma differentiates multicentric origin from intrahepatic metastasis.
The Journal of pathology 2003;199(3):345-53.
2003: Xin-Yuan Guan; Jonathan S T Sham; Lai Shan Tai; Yan Fang; Hong Li; Qiwan Liang
Evidence for another tumor suppressor gene at 17p13.3 distal to TP53 in hepatocellular carcinoma.
Cancer genetics and cytogenetics 2003;140(1):45-8.
2002: Terence C-M Tang; Jonathan S T Sham; Dan Xie; Yan Fang; Ke-Ke Huo; Qiu-Liang Wu; Xin-Yuan Guan
Identification of a candidate oncogene SEI-1 within a minimal amplified region at 19q13.1 in ovarian cancer cell lines.
Cancer research 2002;62(24):7157-61.
2002: Yi Wang; Meng-Chao Wu; Jonathan S T Sham; Weigou Zhang; Wei-Qing Wu; Xin-Yuan Guan
Prognostic significance of c-myc and AIB1 amplification in hepatocellular carcinoma. A broad survey using high-throughput tissue microarray.
Cancer 2002;95(11):2346-52.
2002: Meng Zhang; Jian-ming Wen; Jian-min Xu; Wei-sheng Wang; Liang Hu; Dan Xie; Xin-Yuan Guan
[Establishment and cytogenetic characterization of a human hepatocellular carcinoma cell strain from the embolus in portal vein].
Ai zheng = Aizheng = Chinese journal of cancer 2002;21(11):1203-7.
2002: Siu Tim Cheung; Xin Chen; Xin-Yuan Guan; San Yu Wong; Lai Shan Tai; Irene Oi-Lin Ng; Samuel So; Sheung-Tat Fan
Identify metastasis-associated genes in hepatocellular carcinoma through clonality delineation for multinodular tumor.
Cancer research 2002;62(16):4711-21.
2002: Kok-Lung Chan; Joyce Man-Fong Lee; Xin-Yuan Guan; Sheung-Tat Fan; Irene Oi-Lin Ng
High-density allelotyping of chromosome 8p in hepatocellular carcinoma and clinicopathologic correlation.
Cancer 2002;94(12):3179-85.
2002: Jian-ming Wen; Jie-Fu Huang; Liang Hu; Wei Sheng Wang; Meng Zhang; Jonathan S T Sham; Jian Min Xu; Wei-Fen Zeng; Dan Xie; Li Jian Liang; Xin-Yuan Guan
Establishment and characterization of human metastatic hepatocellular carcinoma cell line.
Cancer genetics and cytogenetics 2002;135(1):91-5.
2002: Xin-Yuan Guan; Hong En Zhang; Hang Zhou; Jonathan S T Sham; Jackie M-W Fung; Jeffrey M. Trent
Characterization of a complex chromosome rearrangement involving 6q in a melanoma cell line by chromosome microdissection.
Cancer genetics and cytogenetics 2002;134(1):65-70.
2002: Jonathan S T Sham; Terence C-M Tang; Yan Fang; Li Sun; Lun-Xiu Qin; Qiu-Liang Wu; Dan Xie; Xin-Yuan Guan
Recurrent chromosome alterations in primary ovarian carcinoma in Chinese women.
Cancer genetics and cytogenetics 2002;133(1):39-44.
2002: Xin-Yuan Guan
Chromosome microdissection.
Methods in molecular biology (Clifton, N.J.) 2002;204():67-76.
2001: Xin-Yuan Guan; Jonathan S T Sham; Terence C-M Tang; Yan Fang; K K Huo; J M Yang
Isolation of a novel candidate oncogene within a frequently amplified region at 3q26 in ovarian cancer.
Cancer research 2001;61(9):3806-9.
2000: Xin-Yuan Guan; Song-Bin Fu; J C Xia; Yan Fang; Jonathan S T Sham; B D Du; H Zhou; S Lu; Bing-quan Wang; Y Z Lin; Q Liang; X M Li; B Du; X M Ning; J R Du; P Li; Jeffrey M. Trent
Recurrent chromosome changes in 62 primary gastric carcinomas detected by comparative genomic hybridization.
Cancer genetics and cytogenetics 2000;123(1):27-34.
2000: Xin-Yuan Guan; Y Fang; J S Sham; D L Kwong; Y Zhang; Q Liang; H Li; H Zhou; Jeffrey M. Trent
Recurrent chromosome alterations in hepatocellular carcinoma detected by comparative genomic hybridization.
Genes, chromosomes & cancer 2000;29(2):110-6.