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Ziqiang Guan

Research Profile

Genes & Molecular Sequences

Molecular Structure

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Inhibitory Concentration 50

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Fermentation

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Chaowei Zhang; John G Ondeyka; Kithsiri B Herath; Hiranthi Jayasuriya; Ziqiang Guan; Deborah L Zink; Lisa Dietrich; Bruce Burgess; Sookhee N Ha; Jun Wang; Sheo B Singh
Platensimycin and platencin congeners from Streptomyces platensis.
Chaowei Zhang; John G Ondeyka; Ziqiang Guan; Lisa Dietrich; Bruce Burgess; Jun Wang; Sheo B Singh
Isolation, structure and biological activities of platensimycin B4 from Streptomyces platensis.
Hiranthi Jayasuriya; Ziqiang Guan; Anne W Dombrowski; Gerald F Bills; Jon D Polishook; Rosalind G Jenkins; Leslie Koch; Tami Crumley; Tamas Tamas; Michelle Dubois; Andrew S Misura; Sandra J Darkin-Rattray; Lynn Gregory; Sheo B Singh
Isolation, structure, and coccidiostat activity of coccidiostatin A.

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All Publications

2011: Chaowei Zhang; John G Ondeyka; Kithsiri B Herath; Hiranthi Jayasuriya; Ziqiang Guan; Deborah L Zink; Lisa Dietrich; Bruce Burgess; Sookhee N Ha; Jun Wang; Sheo B Singh
Platensimycin and platencin congeners from Streptomyces platensis.
Journal of natural products 2011;74(3):329-40.
2009: Chaowei Zhang; John G Ondeyka; Ziqiang Guan; Lisa Dietrich; Bruce Burgess; Jun Wang; Sheo B Singh
Isolation, structure and biological activities of platensimycin B4 from Streptomyces platensis.
The Journal of antibiotics 2009;62(12):699-702.
2007: Hiranthi Jayasuriya; Ziqiang Guan; Anne W Dombrowski; Gerald F Bills; Jon D Polishook; Rosalind G Jenkins; Leslie Koch; Tami Crumley; Tamas Tamas; Michelle Dubois; Andrew S Misura; Sandra J Darkin-Rattray; Lynn Gregory; Sheo B Singh
Isolation, structure, and coccidiostat activity of coccidiostatin A.
Journal of natural products 2007;70(8):1364-7.
2006: Ray Bakhtiar; Ziqiang Guan
Electron capture dissociation mass spectrometry in characterization of peptides and proteins.
Biotechnology letters 2006;28(14):1047-59.
2006: John G Ondeyka; Anne W Dombrowski; Jon P Polishook; Tom Felcetto; Wesley L Shoop; Ziqiang Guan; Sheo B Singh
Isolation and insecticidal/anthelmintic activity of xanthonol, a novel bis-xanthone, from a non-sporulating fungal species.
The Journal of antibiotics 2006;59(5):288-92.
2006: Chaowei Zhang; John G Ondeyka; Kithsiri B Herath; Ziqiang Guan; Javier Collado; Fernando Pelaez; Penny Sue Leavitt; Anne Gurnett; Bakela Nare; Paul A Liberator; Sheo B Singh
Highly substituted terphenyls as inhibitors of parasite cGMP-dependent protein kinase activity.
Journal of natural products 2006;69(4):710-2.
2005: Sheo B Singh; Rosemarie Kelly; Ziqiang Guan; Jon D Polishook; Anne W Domrowski; Javier Collado; Antonio Gonzalez; Fernando Pelaez; Elizabeth Register; Theresa M Kelly; Cynthia Bonfiglio; Joanne M Williamson
New fungal metabolite geranylgeranyltransferase inhibitors with antifungal activity.
Natural product research 2005;19(8):739-47.
2005: Kithsiri B Herath; Hiranthi Jayasuriya; John G Ondeyka; Jon D Polishook; Gerald F Bills; Anne W Dombrowski; Angeles Cabello; Pasquale P Vicario; Hans Zweerink; Ziqiang Guan; Sheo B Singh
Isolation and structures of novel fungal metabolites as chemokine receptor (CCR2) antagonists.
The Journal of antibiotics 2005;58(11):686-94.
2005: John G Ondeyka; Hiranthi Jayasuriya; Kithsiri B Herath; Ziqiang Guan; Marvin Schulman; Javier Collado; Anne W Dombrowski; Soojin S Kwon; Christine McCallum; Neelam Sharma; Karen L Macnaul; Nancy Hayes; John G Menke; Sheo B Singh
Steroidal and triterpenoidal fungal metabolites as ligands of liver X receptors.
The Journal of antibiotics 2005;58(9):559-65.
2005: Kithsiri B Herath; Hiranthi Jayasuriya; Ziqiang Guan; Marvin Schulman; Carolyn Ruby; Neelam Sharma; Karen L Macnaul; John G Menke; Srinivas Kodali; Andrew Galgoci; Jun Wang; Sheo B Singh
Anthrabenzoxocinones from Streptomyces sp. as liver X receptor ligands and antibacterial agents.
Journal of natural products 2005;68(9):1437-40.
2005: Ray Bakhtiar; Ziqiang Guan
Electron capture dissociation mass spectrometry in characterization of post-translational modifications.
Biochemical and biophysical research communications 2005;334(1):1-8.
2005: Hiranthi Jayasuriya; Kithsiri B Herath; John G Ondeyka; Ziqiang Guan; Robert P Borris; Suroojnauth Tiwari; Wil de Jong; Flor Chavez; Jeremy Moss; Dennis W Stevenson; Hans T Beck; Marc Slattery; Nelson Zamora; Marvin Schulman; Aisha Ali; Neelam Sharma; Karen L Macnaul; Nancy Hayes; John G Menke; Sheo B Singh
Diterpenoid, steroid, and triterpenoid agonists of liver X receptors from diversified terrestrial plants and marine sources.
Journal of natural products 2005;68(8):1247-52.
2005: Kithsiri B Herath; Hiranthi Jayasuriya; John G Ondeyka; Ziqiang Guan; Robert P Borris; Eirik Stijfhoorn; Dennis Stevenson; Jianhua Wang; Neelam Sharma; Karen L Macnaul; John G Menke; Aisha Ali; Marvin Schulman; Sheo B Singh
Guttiferone I, a new prenylated benzophenone from Garcinia humilis as a liver X receptor ligand.
Journal of natural products 2005;68(4):617-9.
2005: Chaowei Zhang; John G Ondeyka; Kithsiri B Herath; Ziqiang Guan; Javier Collado; Gonzalo Platas; Fernando Pelaez; Penny Sue Leavitt; Anne Gurnett; Bakela Nare; Paul A Liberator; Sheo B Singh
Tenellones A and B from a Diaporthe sp.: two highly substituted benzophenone inhibitors of parasite cGMP-dependent protein kinase activity.
Journal of natural products 2005;68(4):611-3.
2005: John G Ondeykal; Kithsiri B Herath; Hiranthi Jayasuriya; Jon D Polishook; Gerald F Bills; Anne W Dombrowski; Marina Mojena; Gregory Koch; Jerry DiSalvo; Julie A DeMartino; Ziqiang Guan; Weerachai Nanakorn; Cori M Morenberg; Michael J Balick; Dennis W Stevenson; Marc Slattery; Robert P Borris; Sheo B Singh
Discovery of structurally diverse natural product antagonists of chemokine receptor CXCR3.
Molecular diversity 2005;9(1-3):123-9.
2004: Hiranthi Jayasuriya; Kithsiri B Herath; John G Ondeyka; Jon D Polishook; Gerald F Bills; Anne W Dombrowski; Martin S Springer; Salvatore J Siciliano; Lorraine Malkowitz; Manuel Sanchez; Ziqiang Guan; Suroojnauth Tiwari; Dennis W Stevenson; Robert P Borris; Sheo B Singh
Isolation and structure of antagonists of chemokine receptor (CCR5).
Journal of natural products 2004;67(6):1036-8.
2004: Kithsiri B Herath; Hiranthi Jayasuriya; Gerald F Bills; Jon D Polishook; Anne W Dombrowski; Ziqiang Guan; Peter J Felock; Daria J Hazuda; Sheo B Singh
Isolation, structure, absolute stereochemistry, and HIV-1 integrase inhibitory activity of integrasone, a novel fungal polyketide.
Journal of natural products 2004;67(5):872-4.
2003: Sheo B Singh; Hiranthi Jayasuriya; Raymond Dewey; Jon D Polishook; Anne W Dombrowski; Deborah L Zink; Ziqiang Guan; Javier Collado; Gonzalo Platas; Fernando Pelaez; Peter J Felock; Daria J Hazuda
Isolation, structure, and HIV-1-integrase inhibitory activity of structurally diverse fungal metabolites.
Journal of industrial microbiology & biotechnology 2003;30(12):721-31.
2003: Ziqiang Guan; Nathan A Yates; Ray Bakhtiar
Detection and characterization of methionine oxidation in peptides by collision-induced dissociation and electron capture dissociation.
Journal of the American Society for Mass Spectrometry 2003;14(6):605-13.
2003: Hiranthi Jayasuriya; Ziqiang Guan; Jon D Polishook; Anne W Dombrowski; Peter J Felock; Daria J Hazuda; Sheo B Singh
Isolation, structure, and HIV-1 integrase inhibitory activity of Cytosporic acid, a fungal metabolite produced by a Cytospora sp.
Journal of natural products 2003;66(4):551-3.
2003: John G Ondeyka; Anne W Dombrowski; J P Polishook; Tom Felcetto; Wesley L Shoop; Ziqiang Guan; Sheo B Singh
Isolation and insecticidal activity of mellamide from Aspergillus melleus.
Journal of industrial microbiology & biotechnology 2003;30(4):220-4.
2002: Hiranthi Jayasuriya; Russell Lingham; Pia Graham; Donette Quamina; Lucia Herranz; Olga Genilloud; Magda Gagliardi; Renee Danzeisen; Joanne E Tomassini; Deborah L Zink; Ziqiang Guan; Sheo B Singh
Durhamycin A, a potent inhibitor of HIV Tat transactivation.
Journal of natural products 2002;65(8):1091-5.
2002: Sheo B Singh; Kithsiri B Herath; Ziqiang Guan; Deborah L Zink; Anne W Dombrowski; Jon D Polishook; Keith C Silverman; Russell Lingham; Peter J Felock; Daria J Hazuda
Integramides A and B, two novel non-ribosomal linear peptides containing nine C(alpha)-methyl amino acids produced by fungal fermentations that are inhibitors of HIV-1 integrase.
Organic letters 2002;4(9):1431-4.
2001: Ziqiang Guan; Jerrold M Liesch
Solvation of acylium fragment ions in electrospray ionization quadrupole ion trap and Fourier transform ion cyclotron resonance mass spectrometry.
Journal of mass spectrometry : JMS 2001;36(3):264-76.