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Scott Arn

Research Profile

Living Beings

Procedures

Anatomy

Physiology

Immune Tolerance

Genes & Molecular Sequences

Major Histocompatibility Complex

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Publications

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Raimon Duran-Struuck; Patricia S Cho; Alexander G S Teague; Brian Fishman; Aaron S Fishman; John S Hanekamp; Shannon G Moran; Krzysztof J Wikiel; Kelly K Ferguson; Diana P Lo; Mike Duggan; J Scott Arn; Bob Billiter; Ben Horner; Stuart Houser; Beow Yong Yeap; Susan V Westmoreland; Thomas R Spitzer; Isabel M McMorrow; David H Sachs; Roderick T Bronson; Christene A Huang
Myelogenous leukemia in adult inbred MHC-defined miniature swine: a model for human myeloid leukemias.
Adam Griesemer; A Hirakata; Akira Shimizu; S Moran; A Tena; H Iwaki; Y Ishikawa; P Schule; J Scott Arn; Simon C Robson; Jay A Fishman; Megan Sykes; David H Sachs; Kazuhiko Yamada
Results of gal-knockout porcine thymokidney xenografts.
Adam Griesemer; Masayoshi Okumi; Akira Shimizu; Shannon Moran; Yoshinori Ishikawa; Justin Iorio; J Scott Arn; Kazuhiko Yamada
Upregulation of CD59: potential mechanism of accommodation in a large animal model.

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All Publications

2010: Raimon Duran-Struuck; Patricia S Cho; Alexander G S Teague; Brian Fishman; Aaron S Fishman; John S Hanekamp; Shannon G Moran; Krzysztof J Wikiel; Kelly K Ferguson; Diana P Lo; Mike Duggan; J Scott Arn; Bob Billiter; Ben Horner; Stuart Houser; Beow Yong Yeap; Susan V Westmoreland; Thomas R Spitzer; Isabel M McMorrow; David H Sachs; Roderick T Bronson; Christene A Huang
Myelogenous leukemia in adult inbred MHC-defined miniature swine: a model for human myeloid leukemias.
Veterinary immunology and immunopathology 2010;135(3-4):243-56.
2009: Adam Griesemer; A Hirakata; Akira Shimizu; S Moran; A Tena; H Iwaki; Y Ishikawa; P Schule; J Scott Arn; Simon C Robson; Jay A Fishman; Megan Sykes; David H Sachs; Kazuhiko Yamada
Results of gal-knockout porcine thymokidney xenografts.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2009;9(12):2669-78.
2009: Adam Griesemer; Masayoshi Okumi; Akira Shimizu; Shannon Moran; Yoshinori Ishikawa; Justin Iorio; J Scott Arn; Kazuhiko Yamada
Upregulation of CD59: potential mechanism of accommodation in a large animal model.
Transplantation 2009;87(9):1308-17.
2007: Patricia S Cho; Diana P Lo; Krzysztof J Wikiel; Haley Rowland; Rebecca C Coburn; Isabel M McMorrow; Jennifer G Goodrich; J Scott Arn; Robert A Billiter; Stuart L Houser; Akira Shimizu; Yong-Guang Yang; David H Sachs; Christene A Huang
Establishment of transplantable porcine tumor cell lines derived from MHC-inbred miniature swine.
Blood 2007;110(12):3996-4004.
2003: Joshua D Mezrich; Gary W Haller; J Scott Arn; Stuart L Houser; Joren C Madsen; David H Sachs
Histocompatible miniature swine: an inbred large-animal model.
Transplantation 2003;75(6):904-7.
2003: David W Mathes; Mark A Randolph; Mario G Solari; Jamal A Nazzal; G Petur Nielsen; J Scott Arn; David H Sachs; W P Andrew Lee
Split tolerance to a composite tissue allograft in a swine model.
Transplantation 2003;75(1):25-31.
2002: Matthew Heinz; Christene A Huang; David W Emery; Maria A Giovino; Annie LeGuern; Barbara Kurilla-Mahon; Pierre R Theodore; J Scott Arn; Megan Sykes; Richard Mulligan; Julian D Down; David H Sachs; Margaret A Goodell
Use of CD9 expression to enrich for porcine hematopoietic progenitors.
Experimental hematology 2002;30(7):809-15.
2002: David W Mathes; Mark A Randolph; Judy L Bourget; G Petur Nielsen; Vincent R Ferrera; J Scott Arn; David H Sachs; W P Andrew Lee
Recipient bone marrow engraftment in donor tissue after long-term tolerance to a composite tissue allograft.
Transplantation 2002;73(12):1880-5.
2001: Yong Zhao; Jose-Ignacio Rodriguez-Barbosa; Kirsten G Swenson; Guiling Zhao; J Scott Arn; Megan Sykes
Highly disparate xenogeneic skin graft tolerance induction by fetal pig thymus in thymectomized mice: Conditioning requirements and the role of coimplantation of fetal pig liver.
Transplantation 2001;72(10):1608-15.
2001: Jose-Ignacio Rodriguez-Barbosa; Yong Zhao; Rolf N Barth; Guiling Zhao; J Scott Arn; David H Sachs; Megan Sykes
Enhanced CD4 reconstitution by grafting neonatal porcine tissue in alternative locations is associated with donor-specific tolerance and suppression of preexisting xenoreactive T cells.
Transplantation 2001;72(7):1223-31.
2001: James S Allan; GA Rose; JK Choo; J Scott Arn; L Vesga; Kwabena Mawulawde; JK Slisz; K Allison; Joren C Madsen
Morphometric analysis of miniature swine hearts as potential human xenografts.
Xenotransplantation 2001;8(2):90-3.
2001: Yong Zhao; Jose-Ignacio Rodriguez-Barbosa; Guiling Zhao; Juanita Shaffer; J Scott Arn; Megan Sykes
Maturation and function of mouse T-cells with a transgenic TCR positively selected by highly disparate xenogeneic porcine MHC.
Cellular and molecular biology (Noisy-le-Grand, France) 2001;47(1):217-28.
2000: Yong Zhao; Kirsten G Swenson; Thomas Wekerle; Jose-Ignacio Rodriguez-Barbosa; J Scott Arn; Megan Sykes
The critical role of mouse CD4+ cells in the rejection of highly disparate xenogeneic pig thymus grafts.
Xenotransplantation 2000;7(2):129-37.
2000: Yong Zhao; Jose-Ignacio Rodriguez-Barbosa; Kirsten G Swenson; Rolf N Barth; Akira Shimizu; J Scott Arn; David H Sachs; Megan Sykes
The induction of specific pig skin graft tolerance by grafting with neonatal pig thymus in thymectomized mice.
Transplantation 2000;69(7):1447-51.
2000: RS Lee; Kazuhiko Yamada; Karl L Womer; E P Pillsbury; Kenneth S Allison; A E Marolewski; D Geng; A D Thall; J Scott Arn; David H Sachs; Mohamed H Sayegh; Joren C Madsen
Blockade of CD28-B7, but not CD40-CD154, prevents costimulation of allogeneic porcine and xenogeneic human anti-porcine T cell responses.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(6):3434-44.
1999: Christene A Huang; T Lorf; J Scott Arn; G C Koo; T Blake; David H Sachs
Characterization of a monoclonal anti-porcine CD3 antibody.
Xenotransplantation 1999;6(3):201-12.
1999: Boris Nikolic; J P Gardner; David T Scadden; J Scott Arn; David H Sachs; Megan Sykes
Normal development in porcine thymus grafts and specific tolerance of human T cells to porcine donor MHC.
Journal of immunology (Baltimore, Md. : 1950) 1999;162(6):3402-7.
1999: James S Allan; GA Rose; JK Choo; J Scott Arn; L Vesga; Kwabena Mawulawde; JK Slisz; K Allison; Joren C Madsen
Morphometric analyses to predict appropriate donor size for swine-to-human cardiac xenotransplantation.
Transplantation proceedings 1999;31(1-2):975-7.
1998: James S Allan; JK Slisz; L Vesga; J Scott Arn; Kazuhiko Yamada; David H Sachs; Joren C Madsen
Enhanced efficacy of repeated anti-CD8 monoclonal antibody therapy by high-dose cyclosporine treatment.
Transplantation proceedings 1998;30(8):4062-3.
1998: Francesco L Ierino; Kazuhiko Yamada; T Lorf; J Scott Arn; David H Sachs
Mechanism of tolerance to class I-mismatched renal allografts in miniature swine: regulation of interleukin-2 receptor alpha-chain expression on CD8 peripheral blood lymphocytes of tolerant animals.
Transplantation 1998;66(4):454-60.
1997: James S Allan; JK Choo; L Vesga; J Scott Arn; M R Pins; David H Sachs; Joren C Madsen
Cardiac allograft vasculopathy is abrogated by anti-CD8 monoclonal antibody therapy.
The Annals of thoracic surgery 1997;64(4):1019-25.
1997: Yong Zhao; JJ Sergio; Kirsten G Swenson; J Scott Arn; David H Sachs; Megan Sykes
Positive and negative selection of functional mouse CD4 cells by porcine MHC in pig thymus grafts.
Journal of immunology (Baltimore, Md. : 1950) 1997;159(5):2100-7.
1997: Yong Zhao; Jay A Fishman; JJ Sergio; J L Oliveros; Denise A Pearson; GL Szot; Robert A Wilkinson; J Scott Arn; David H Sachs; Megan Sykes
Immune restoration by fetal pig thymus grafts in T cell-depleted, thymectomized mice.
Journal of immunology (Baltimore, Md. : 1950) 1997;158(4):1641-9.
1997: Yong Zhao; JJ Sergio; Denise A Pearson; GL Szot; J Scott Arn; David H Sachs; Megan Sykes
Repopulation of mouse CD4 cells in BALB/c nude mice receiving fetal pig thymus/liver grafts.
Transplantation proceedings 1997;29(1-2):1228-9.
1996: Yong Zhao; Kirsten G Swenson; JJ Sergio; J Scott Arn; D H Sachs; Megan Sykes
Skin graft tolerance across a discordant xenogeneic barrier.
Nature medicine 1996;2(11):1211-6.
1996: P R Gianello; Kazuhiko Yamada; J M Fishbein; T Lorf; Volker Nickeleit; Robert B Colvin; J Scott Arn; D H Sachs
Long-term acceptance of primarily vascularized renal allografts in miniature swine. Systemic tolerance versus graft adaptation.
Transplantation 1996;61(3):503-6.
1995: P R Gianello; J M Fishbein; Bruce R Rosengard; T Lorf; D M Vitiello; J Scott Arn; D H Sachs
Tolerance to class I-disparate renal allografts in miniature swine. Maintenance of tolerance despite induction of specific antidonor CTL responses.
Transplantation 1995;59(5):772-7.
1994: L A Lee; H A Gritsch; JJ Sergio; J Scott Arn; R M Glaser; T Sablinski; D H Sachs; Megan Sykes
Specific tolerance across a discordant xenogeneic transplantation barrier.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(23):10864-7.
1994: C V Smith; T Sablinski; J Scott Arn; D E Myers; Bruce R Rosengard; fatih uckun; D H Sachs
In vivo treatment with monoclonal antibodies directed against CD4 and CD8 antigens in miniature swine.
Journal of immunotherapy with emphasis on tumor immunology : official journal of the Society for Biological Therapy 1994;16(2):105-14.
1994: L A Lee; H A Gritsch; J Scott Arn; DW Emery; R M Glaser; T Sablinski; D H Sachs; Megan Sykes
Induction of tolerance to pig antigens in mice grafted with fetal pig thymus/liver grafts.
Transplantation proceedings 1994;26(3):1300-1.
1994: H A Gritsch; R M Glaser; DW Emery; L A Lee; C V Smith; T Sablinski; J Scott Arn; D H Sachs; Megan Sykes
The importance of nonimmune factors in reconstitution by discordant xenogeneic hematopoietic cells.
Transplantation 1994;57(6):906-17.
1994: DW Emery; T Sablinski; J Scott Arn; Christian Leguern; D H Sachs
Bone marrow culture and transduction of stem cells in a miniature swine model.
Blood cells 1994;20(2-3):498-502; discussion 502-3.
1992: T M Sundt; J Scott Arn; D H Sachs
Patterns of T cell-accessory cell interaction in the generation of primary alloresponses in the pig.
Transplantation 1992;54(5):911-6.