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Remo Guerrini

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Chemicals & Drugs

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Anatomy

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Amino Acid Sequence

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Competitive Binding

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Publications

TOP 3
Vitale Giovanni; Ruggieri Valentina; Filaferro Monica; Frigeri Claudio; Alboni Silvia; Tascedda Fabio; Brunello Nicoletta; Guerrini Remo; Cifani Carlo; Massi Maurizio
Chronic treatment with the selective NOP receptor antagonist [Nphe(1),Arg (14),Lys (15)]N/OFQ-NH (2) (UFP-101) reverses the behavioural and biochemical effects of unpredictable chronic mild stress in rats.
Fedeli Amalia; Braconi Simone; Economidou Daina; Cannella Nazzareno; Kallupi Marsida; Guerrini Remo; Calò Girolamo; Cifani Carlo; Massi Maurizio; Ciccocioppo Roberto
The paraventricular nucleus of the hypothalamus is a neuroanatomical substrate for the inhibition of palatable food intake by neuropeptide S.
Castro A A; Casagrande T S; Moretti M; Constantino L; Petronilho F; Guerra G C B; Calo' G; Guerrini R; Dal-Pizzol F; Quevedo J; Gavioli E C
Lithium attenuates behavioral and biochemical effects of neuropeptide S in mice.

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All Publications

2009: Vitale Giovanni; Ruggieri Valentina; Filaferro Monica; Frigeri Claudio; Alboni Silvia; Tascedda Fabio; Brunello Nicoletta; Guerrini Remo; Cifani Carlo; Massi Maurizio
Chronic treatment with the selective NOP receptor antagonist [Nphe(1),Arg (14),Lys (15)]N/OFQ-NH (2) (UFP-101) reverses the behavioural and biochemical effects of unpredictable chronic mild stress in rats.
Psychopharmacology 2009;207(2):173-89.
2009: Fedeli Amalia; Braconi Simone; Economidou Daina; Cannella Nazzareno; Kallupi Marsida; Guerrini Remo; Calò Girolamo; Cifani Carlo; Massi Maurizio; Ciccocioppo Roberto
The paraventricular nucleus of the hypothalamus is a neuroanatomical substrate for the inhibition of palatable food intake by neuropeptide S.
The European journal of neuroscience 2009;30(8):1594-602.
2009: Castro A A; Casagrande T S; Moretti M; Constantino L; Petronilho F; Guerra G C B; Calo' G; Guerrini R; Dal-Pizzol F; Quevedo J; Gavioli E C
Lithium attenuates behavioral and biochemical effects of neuropeptide S in mice.
Peptides 2009;30(10):1914-20.
2009: Trapella Claudio; Fischetti Carmela; Pela' Michela; Lazzari Ilaria; Guerrini Remo; Calo' Girolamo; Rizzi Anna; Camarda Valeria; Lambert David G; McDonald John; Regoli Domenico; Salvadori Severo
Structure-activity studies on the nociceptin/orphanin FQ receptor antagonist 1-benzyl-N-{3-[spiroisobenzofuran-1(3H),4'-piperidin-1-yl]propyl} pyrrolidine-2-carboxamide.
Bioorganic & medicinal chemistry 2009;17(14):5080-95.
2009: Dietis N; Guerrini R; Calo G; Salvadori S; Rowbotham D J; Lambert D G
Simultaneous targeting of multiple opioid receptors: a strategy to improve side-effect profile.
British journal of anaesthesia 2009;103(1):38-49.
2009: Guerrini Remo; Camarda Valeria; Trapella Claudio; Caló Girolamo; Rizzi Anna; Ruzza Chiara; Fiorini Stella; Marzola Erika; Reinscheid Rainer K; Regoli Domenico; Salvadori Severo
Further studies at neuropeptide s position 5: discovery of novel neuropeptide S receptor antagonists.
Journal of medicinal chemistry 2009;52(13):4068-71.
2009: Fischetti Carmela; Camarda Valeria; Rizzi Anna; Pelà Michela; Trapella Claudio; Guerrini Remo; McDonald John; Lambert David G; Salvadori Severo; Regoli Domenico; Calo' Girolamo
Pharmacological characterization of the nociceptin/orphanin FQ receptor non peptide antagonist Compound 24.
European journal of pharmacology 2009;614(1-3):50-7.
2009: Batuwangala Madura; Camarda Valeria; McDonald John; Marzola Erika; Lambert David G; Ng Leong L; Calo' Girolamo; Regoli Domenico; Trapella Claudio; Guerrini Remo; Salvadori Severo
Structure-activity relationship study on Tyr9 of urotensin-II(4-11): identification of a partial agonist of the UT receptor.
Peptides 2009;30(6):1130-6.
2009: Camarda Valeria; Fischetti Carmela; Anzellotti Nicholas; Molinari Paola; Ambrosio Caterina; Kostenis Evi; Regoli Domenico; Trapella Claudio; Guerrini Remo; Severo Salvadori; Calo Girolamo
Pharmacological profile of NOP receptors coupled with calcium signaling via the chimeric protein Galphaqi5.
Naunyn-Schmiedeberg's archives of pharmacology 2009;379(6):599-607.
2009: Grandi Daniela; Solenghi Elvira; Guerrini Remo; Broccardo Maria; Agostini Simona; Petrella Carla; Scaccianoce Sergio; Improta Giovanna; Morini Giuseppina
The hypothalamus-pituitary-adrenal axis does not influence the protective effects of nociceptin/orphanin FQ on the rat gastric mucosa.
Regulatory peptides 2009;154(1-3):32-8.
2009: Fischetti Carmela; Rizzi Anna; Gavioli Elaine C; Marzola Giuliano; Trapella Claudio; Guerrini Remo; Petersen Jorgen S; Calo Girolamo
Further studies on the pharmacological features of the nociceptin/orphanin FQ receptor ligand ZP120.
Peptides 2009;30(2):248-55.
2009: Camarda Valeria; Rizzi Anna; Ruzza Chiara; Zucchini Silvia; Marzola Giuliano; Marzola Erika; Guerrini Remo; Salvadori Severo; Reinscheid Rainer K; Regoli Domenico; Calò Girolamo
In vitro and in vivo pharmacological characterization of the neuropeptide s receptor antagonist [D-Cys(tBu)5]neuropeptide S.
The Journal of pharmacology and experimental therapeutics 2009;328(2):549-55.
2009: Guerrini Remo; Camarda Valeria; Trapella Claudio; Calò Girolamo; Rizzi Anna; Ruzza Chiara; Fiorini Stella; Marzola Erika; Reinscheid Rainer K; Regoli Domenico; Salvadori Severo
Synthesis and biological activity of human neuropeptide S analogues modified in position 5: identification of potent and pure neuropeptide S receptor antagonists.
Journal of medicinal chemistry 2009;52(2):524-9.
2008: Carvalho Dickson; Petronilho Fabricia; Vuolo Francieli; Machado Roberta Albino; Constantino Larissa; Guerrini Remo; Calo Girolamo; Gavioli Elaine Cristina; Streck Emílio Luiz; Dal-Pizzol Felipe
The nociceptin/orphanin FQ-NOP receptor antagonist effects on an animal model of sepsis.
Intensive care medicine 2008;34(12):2284-90.
2008: Ibba Massimo; Kitayama Masato; McDonald John; Calo Girolamo; Guerrini Remo; Farkas Judit; Toth Geza; Lambert David G
Binding of the novel radioligand [(3)H]UFP-101 to recombinant human and native rat nociceptin/orphanin FQ receptors.
Naunyn-Schmiedeberg's archives of pharmacology 2008;378(6):553-61.
2008: Vitale Giovanni; Filaferro Monica; Ruggieri Valentina; Pennella Sonia; Frigeri Claudio; Rizzi Anna; Guerrini Remo; Calò Girolamo
Anxiolytic-like effect of neuropeptide S in the rat defensive burying.
Peptides 2008;29(12):2286-91.
2008: Gralka Ewa; Valensin Daniela; Porciatti Elena; Gajda Carolina; Gaggelli Elena; Valensin Gianni; Kamysz Wojciech; Nadolny Rafal; Guerrini Remo; Bacco Dimitri; Remelli Maurizio; Kozlowski Henryk
CuII binding sites located at His-96 and His-111 of the human prion protein: thermodynamic and spectroscopic studies on model peptides.
Dalton transactions (Cambridge, England : 2003) 2008;(38):5207-19.
2008: Camarda Valeria; Trapella Claudio; Calo' Girolamo; Guerrini Remo; Rizzi Anna; Ruzza Chiara; Fiorini Stella; Marzola Erika; Reinscheid Rainer K; Regoli Domenico; Salvadori Severo
Structure-activity study at positions 3 and 4 of human neuropeptide S.
Bioorganic & medicinal chemistry 2008;16(19):8841-5.
2008: Savoia Dianella; Guerrini Remo; Marzola Erika; Salvadori Severo
Synthesis and antimicrobial activity of dermaseptin S1 analogues.
Bioorganic & medicinal chemistry 2008;16(17):8205-9.
2008: Ono Tomoko; Kawaguchi Yoko; Kudo Mihoko; Kushikata Tetsuya; Hashiba Eiji; Yoshida Hitoshi; Kudo Tsuyoshi; Furukawa Kenichi; Douglas Stephen A; Guerrini Remo; Calo' Girolamo; Hirota Kazuyoshi
Urotensin II evokes neurotransmitter release from rat cerebrocortical slices.
Neuroscience letters 2008;440(3):275-9.
2008: Gavioli Elaine C; Duarte Filipe S; Guerrini Remo; Calo Girolamo; Rae Giles A; M De Lima Thereza C
GABA(A) signalling is involved in N/OFQ anxiolytic-like effects but not in nocistatin anxiogenic-like action as evaluated in the mouse elevated plus maze.
Peptides 2008;29(8):1404-12.
2008: Broccardo M; Agostini S; Petrella C; Guerrini R; Improta G
Central and peripheral role of the nociceptin/orphaninFQ system on normal and disturbed colonic motor function and faecal pellet output in the rat.
Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 2008;20(8):939-48.
2008: Rizzi A; Vergura R; Marzola G; Ruzza C; Guerrini R; Salvadori S; Regoli D; Calo G
Neuropeptide S is a stimulatory anxiolytic agent: a behavioural study in mice.
British journal of pharmacology 2008;154(2):471-9.
2008: Marzola Erika; Camarda Valeria; Batuwangala Madura; Lambert David G; Calo' Girolamo; Guerrini Remo; Trapella Claudio; Regoli Domenico; Tomatis Roberto; Salvadori Severo
Structure-activity relationship study of position 4 in the urotensin-II receptor ligand U-II(4-11).
Peptides 2008;29(5):674-9.
2008: Camarda Valeria; Trapella Claudio; Calo Girolamo; Guerrini Remo; Rizzi Anna; Ruzza Chiara; Fiorini Stella; Marzola Erika; Reinscheid Rainer K; Regoli Domenico; Salvadori Severo
Synthesis and biological activity of human neuropeptide S analogues modified in position 2.
Journal of medicinal chemistry 2008;51(3):655-8.
2008: Selvatici Rita; Falzarano Sofia; Franceschetti Lara; Mollica Adriano; Guerrini Remo; Siniscalchi Anna; Spisani Susanna
Study of synthetic peptides derived from the PKI55 protein, a protein kinase C modulator, in human neutrophils stimulated by the methyl ester derivative of the hydrophobic N-formyl tripeptide for-Met-Leu-Phe-OH.
The FEBS journal 2008;275(3):449-57.
2008: Vergura Raffaella; Balboni Gianfranco; Spagnolo Barbara; Gavioli Elaine; Lambert David G; McDonald John; Trapella Claudio; Lazarus Lawrence H; Regoli Domenico; Guerrini Remo; Salvadori Severo; Caló Girolamo
Anxiolytic- and antidepressant-like activities of H-Dmt-Tic-NH-CH(CH2-COOH)-Bid (UFP-512), a novel selective delta opioid receptor agonist.
Peptides 2008;29(1):93-103.
2008: Kuo Chia-Ju; Liao Yan-Yu; Guerrini Remo; Calo' Girolamo; Chiou Lih-Chu
Quantitative study of [(pF)Phe4,Arg14,Lys15]nociceptin/orphanin FQ-NH2 (UFP-102) at NOP receptors in rat periaqueductal gray slices.
European journal of pharmacology 2008;579(1-3):110-5.
2007: Brookes Zoë L S; Stedman Emily N; Guerrini Remo; Lawton Bethan K; Calo Girolamo; Lambert David G
Proinflammatory and vasodilator effects of nociceptin/orphanin FQ in the rat mesenteric microcirculation are mediated by histamine.
American journal of physiology. Heart and circulatory physiology 2007;293(5):H2977-85.
2007: Broccardo M; Guerrini R; Morini G; Polidori C; Agostini S; Petrella C; Improta G
The gastric effects of UFP-112, a new nociceptin/orphanin receptor agonist, in physiological and pathological conditions.
Peptides 2007;28(10):1974-81.
2007: Tancredi Teodorico; Guerrini Remo; Marzola Erika; Trapella Claudio; Calo Girolamo; Regoli Domenico; Reinscheid Rainer K; Camarda Valeria; Salvadori Severo; Temussi Piero Andrea
Conformation-activity relationship of neuropeptide S and some structural mutants: helicity affects their interaction with the receptor.
Journal of medicinal chemistry 2007;50(18):4501-8.
2007: Grandi Daniela; Solenghi Elvira; Guerrini Remo; Polidori Carlo; Massi Maurizio; Morini Giuseppina
Nociceptin/orphanin FQ prevents gastric damage induced by cold-restraint stress in the rat by acting in the periphery.
Peptides 2007;28(8):1572-9.
2007: Kitayama M; McDonald J; Barnes T A; Calo' G; Guerrini R; Rowbotham D J; Lambert D G
In vitro pharmacological characterisation of a novel cyclic nociceptin/orphanin FQ analogue c[Cys(7,10)]N/OFQ(1-13)NH (2).
Naunyn-Schmiedeberg's archives of pharmacology 2007;375(6):369-76.
2007: Arduin Marika; Spagnolo Barbara; Calò Girolamo; Guerrini Remo; Carrà Giacomo; Fischetti Carmela; Trapella Claudio; Marzola Erika; McDonald John; Lambert David G; Regoli Domenico; Salvadori Severo
Synthesis and biological activity of nociceptin/orphanin FQ analogues substituted in position 7 or 11 with Calpha,alpha-dialkylated amino acids.
Bioorganic & medicinal chemistry 2007;15(13):4434-43.
2007: Rizzi Anna; Spagnolo Barbara; Wainford Richard D; Fischetti Carmela; Guerrini Remo; Marzola Giuliano; Baldisserotto Anna; Salvadori Severo; Regoli Domenico; Kapusta Daniel R; Calo Girolamo
In vitro and in vivo studies on UFP-112, a novel potent and long lasting agonist selective for the nociceptin/orphanin FQ receptor.
Peptides 2007;28(6):1240-51.
2007: Nazzaro Cristiano; Rizzi Anna; Salvadori Severo; Guerrini Remo; Regoli Domenico; Zeilhofer Hanns Ulrich; Calo Girolamo
UFP-101 antagonizes the spinal antinociceptive effects of nociceptin/orphanin FQ: behavioral and electrophysiological studies in mice.
Peptides 2007;28(3):663-9.
2007: Berti Francesco; Gaggelli Elena; Guerrini Remo; Janicka Anna; Kozlowski Henryk; Legowska Anna; Miecznikowska Hanna; Migliorini Caterina; Pogni Rebecca; Remelli Maurizio; Rolka Krzysztof; Valensin Daniela; Valensin Gianni
Structural and dynamic characterization of copper(II) binding of the human prion protein outside the octarepeat region.
Chemistry (Weinheim an der Bergstrasse, Germany) 2007;13(7):1991-2001.
2006: Lazzeri Massimo; Calò Girolamo; Spinelli Michele; Malaguti Silvia; Guerrini Remo; Salvadori Severo; Beneforti Patrizia; Regoli Domenico; Turini Damiano
Daily intravesical instillation of 1 mg nociceptin/orphanin FQ for the control of neurogenic detrusor overactivity: a multicenter, placebo controlled, randomized exploratory study.
The Journal of urology 2006;176(5):2098-102.
2006: Cifani Carlo; Guerrini Remo; Massi Maurizio; Polidori Carlo
Chronic intracerebroventricular infusion of nociceptin/orphanin FQ increases food and ethanol intake in alcohol-preferring rats.
Peptides 2006;27(11):2803-10.
2006: Rizzi Anna; Nazzaro Cristiano; Marzola G Giuliano; Zucchini Silvia; Trapella Claudio; Guerrini Remo; Zeilhofer Hanns Ulrich; Regoli Domenico; Calo' Girolamo
Endogenous nociceptin/orphanin FQ signalling produces opposite spinal antinociceptive and supraspinal pronociceptive effects in the mouse formalin test: pharmacological and genetic evidences.
Pain 2006;124(1-2):100-8.
2006: Roth Adelheid L; Marzola Erika; Rizzi Anna; Arduin Marika; Trapella Claudio; Corti Corrado; Vergura Raffaella; Martinelli Prisca; Salvadori Severo; Regoli Domenico; Corsi Mauro; Cavanni Paolo; Caló Girolamo; Guerrini Remo
Structure-activity studies on neuropeptide S: identification of the amino acid residues crucial for receptor activation.
The Journal of biological chemistry 2006;281(30):20809-16.
2006: Gündüz Ozge; Rizzi Anna; Baldisserotto Anna; Guerrini Remo; Spagnolo Barbara; Gavioli Elaine C; Kocsis László; Magyar Anna; Benyhe Sándor; Borsodi Anna; Calò Girolamo
In vitro and in vivo pharmacological characterization of the nociceptin/orphanin FQ receptor ligand Ac-RYYRIK-ol.
European journal of pharmacology 2006;539(1-2):39-48.
2006: Song Wei; McDonald John; Camarda Valeria; Calo Girolamo; Guerrini Remo; Marzola Erika; Thompson Jonathan P; Rowbotham David J; Lambert David G
Cell and tissue responses of a range of Urotensin II analogs at cloned and native urotensin II receptors. Evidence for coupling promiscuity.
Naunyn-Schmiedeberg's archives of pharmacology 2006;373(2):148-57.
2006: Musi Valeria; Birdsall Berry; Fernandez-Ballester Gregorio; Guerrini Remo; Salvatori Severo; Serrano Luis; Pastore Annalisa
New approaches to high-throughput structure characterization of SH3 complexes: the example of Myosin-3 and Myosin-5 SH3 domains from S. cerevisiae.
Protein science : a publication of the Protein Society 2006;15(4):795-807.
2006: Tomaselli Simona; Esposito Veronica; Vangone Paolo; van Nuland Nico A J; Bonvin Alexandre M J J; Guerrini Remo; Tancredi Teodorico; Temussi Piero A; Picone Delia
The alpha-to-beta conformational transition of Alzheimer's Abeta-(1-42) peptide in aqueous media is reversible: a step by step conformational analysis suggests the location of beta conformation seeding.
Chembiochem : a European journal of chemical biology 2006;7(2):257-67.
2006: Trapella Claudio; Guerrini Remo; Piccagli Laura; Calo' Girolamo; Carra' Giacomo; Spagnolo Barbara; Rubini Samantha; Fanton Giulia; Hebbes Christopher; McDonald John; Lambert David G; Regoli Domenico; Salvadori Severo
Identification of an achiral analogue of J-113397 as potent nociceptin/orphanin FQ receptor antagonist.
Bioorganic & medicinal chemistry 2006;14(3):692-704.
2006: Camarda Valeria; Spagnol Martina; Song Wei; Vergura Raffaella; Roth Adelheid L; Thompson Jonathan P; Rowbotham David J; Guerrini Remo; Marzola Erika; Salvadori Severo; Cavanni Paolo; Regoli Domenico; Douglas Stephen A; Lambert David G; Calò Girolamo
In vitro and in vivo pharmacological characterization of the novel UT receptor ligand [Pen5,DTrp7,Dab8]urotensin II(4-11) (UFP-803).
British journal of pharmacology 2006;147(1):92-100.
2005: Balboni Gianfranco; Guerrini Remo; Salvadori Severo; Negri Lucia; Giannini Elisa; Bryant Sharon D; Jinsmaa Yunden; Lazarus Lawrence H
Conversion of the potent delta-opioid agonist H-Dmt-Tic-NH-CH(2)-bid into delta-opioid antagonists by N(1)-benzimidazole alkylation(1).
Journal of medicinal chemistry 2005;48(26):8112-4.
2005: Marti Matteo; Mela Flora; Fantin Martina; Zucchini Silvia; Brown Jeffrey M; Witta Jassir; Di Benedetto Manuela; Buzas Beata; Reinscheid Rainer K; Salvadori Severo; Guerrini Remo; Romualdi Patrizia; Candeletti Sanzio; Simonato Michele; Cox Brian M; Morari Michele
Blockade of nociceptin/orphanin FQ transmission attenuates symptoms and neurodegeneration associated with Parkinson's disease.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2005;25(42):9591-601.
2005: Broccardo M; Linari G; Guerrini R; Agostini S; Petrella C; Improta G
The effects of [Arg14, Lys15] nociceptin/orphanin FQ, a highly potent agonist of the NOP receptor, on in vitro and in vivo gastrointestinal functions.
Peptides 2005;26(9):1590-7.
2005: Remelli Maurizio; Donatoni Martina; Guerrini Remo; Janicka Anna; Pretegiani Pierluigi; Kozlowski Henryk
Copper-ion interaction with the 106-113 domain of the prion protein: a solution-equilibria study on model peptides.
Dalton transactions (Cambridge, England : 2003) 2005;(17):2876-85.
2005: Polidori Carlo; Massi Maurizio; Guerrini Remo; Grandi Daniela; Lupo Daniela; Morini Giuseppina
Peripheral mechanisms involved in gastric mucosal protection by intracerebroventricular and intraperitoneal nociceptin in rats.
Endocrinology 2005;146(9):3861-7.
2005: Basso Marco; Risse Paul André; Naline Emmanuel; Calo Girolamo; Guerrini Remo; Regoli Domenico; Advenier Charles
Nociceptin/orphanin FQ inhibits electrically induced contractions of the human bronchus via NOP receptor activation.
Peptides 2005;26(8):1492-6.
2005: Trombella S; Vergura R; Falzarano S; Guerrini R; Calo G; Spisani S
Nociceptin/orphanin FQ stimulates human monocyte chemotaxis via NOP receptor activation.
Peptides 2005;26(8):1497-502.
2005: Kapusta Daniel R; Burmeister Melissa A; Calo' Girolamo; Guerrini Remo; Gottlieb Helmut B; Kenigs Velga A
Functional selectivity of nociceptin/orphanin FQ peptide receptor partial agonists on cardiovascular and renal function.
The Journal of pharmacology and experimental therapeutics 2005;314(2):643-51.
2005: Carra' G; Calo' G; Spagnolo B; Guerrini R; Arduin M; Marzola E; Trapella C; Regoli D; Salvadori S
Tryptophan replacement in the nociceptin/orphanin FQ receptor ligand Ac-RYYRWK-NH2.
The journal of peptide research : official journal of the American Peptide Society 2005;66(1):39-47.
2005: Marchetti Nicola; Dondi Francesco; Felinger Attila; Guerrini Remo; Salvadori Severo; Cavazzini Alberto
Modeling of overloaded gradient elution of nociceptin/orphanin FQ in reversed-phase liquid chromatography.
Journal of chromatography. A 2005;1079(1-2):162-72.
2005: Chiou Lih-Chu; Liao Yan-Yu; Guerrini Remo; Calo' Girolamo
[Nphe1,Arg14,Lys15]N/OFQ-NH2 is a competitive antagonist of NOP receptors in the periaqueductal gray.
European journal of pharmacology 2005;515(1-3):47-53.
2005: Guerrini Remo; Caló Girolamo; Lambert David G; Carrá Giacomo; Arduin Marika; Barnes Tim A; McDonald John; Rizzi Daniela; Trapella Claudio; Marzola Erika; Rowbotham David J; Regoli Domenico; Salvadori Severo
N- and C-terminal modifications of nociceptin/orphanin FQ generate highly potent NOP receptor ligands.
Journal of medicinal chemistry 2005;48(5):1421-7.
2005: Tancredi Teodorico; Carrà Giacomo; Guerrini Remo; Arduin Marika; Calò Girolamo; Regoli Domenico; Salvadori Severo; Temussi Piero Andrea
The interaction of highly helical structural mutants with the NOP receptor discloses the role of the address domain of nociceptin/orphanin FQ.
Chemistry (Weinheim an der Bergstrasse, Germany) 2005;11(7):2061-70.
2005: D'Agostino Bruno; Marrocco Giuseppina; De Nardo Marilisa; Calò Girolamo; Guerrini Remo; Gallelli Luca; Advenier Charles; Rossi Francesco
Activation of the nociceptin/orphanin FQ receptor reduces bronchoconstriction and microvascular leakage in a rabbit model of gastroesophageal reflux.
British journal of pharmacology 2005;144(6):813-20.
2005: Carrà Giacomo; Rizzi Anna; Guerrini Remo; Barnes Timothy A; McDonald John; Hebbes Christopher P; Mela Flora; Kenigs Velga A; Marzola Giuliano; Rizzi Daniela; Gavioli Elaine; Zucchini Silvia; Regoli Domenico; Morari Michele; Salvadori Severo; Rowbotham David J; Lambert David G; Kapusta Daniel R; Calo' Girolamo
[(pF)Phe4,Arg14,Lys15]N/OFQ-NH2 (UFP-102), a highly potent and selective agonist of the nociceptin/orphanin FQ receptor.
The Journal of pharmacology and experimental therapeutics 2005;312(3):1114-23.
2005: Guerrini Remo; Camarda Valeria; Marzola Erika; Arduin Marika; Calo Girolamo; Spagnol Martina; Rizzi Anna; Salvadori Severo; Regoli Domenico
Structure-activity relationship study on human urotensin II.
Journal of peptide science : an official publication of the European Peptide Society 2005;11(2):85-90.
2005: Morini Giuseppina; De Caro Giuseppe; Guerrini Remo; Massi Maurizio; Polidori Carlo
Nociceptin/orphanin FQ prevents ethanol-induced gastric lesions in the rat.
Regulatory peptides 2005;124(1-3):203-7.
2005: Calo Girolamo; Guerrini Remo; Rizzi Anna; Salvadori Severo; Burmeister Melissa; Kapusta Daniel R; Lambert David G; Regoli Domenico
UFP-101, a peptide antagonist selective for the nociceptin/orphanin FQ receptor.
CNS drug reviews 2005;11(2):97-112.
2004: Marti Matteo; Mela Flora; Guerrini Remo; Calò Girolamo; Bianchi Clementina; Morari Michele
Blockade of nociceptin/orphanin FQ transmission in rat substantia nigra reverses haloperidol-induced akinesia and normalizes nigral glutamate release.
Journal of neurochemistry 2004;91(6):1501-4.
2004: Martin Stephen R; Biekofsky Rodolfo R; Skinner Murray A; Guerrini Remo; Salvadori Severo; Feeney James; Bayley Peter M
Interaction of calmodulin with the phosphofructokinase target sequence.
FEBS letters 2004;577(1-2):284-8.
2004: Vergura Raffaella; Camarda Valeria; Rizzi Anna; Spagnol Martina; Guerrini Remo; Calo' Girolamo; Salvadori Severo; Regoli Domenico
Urotensin II stimulates plasma extravasation in mice via UT receptor activation.
Naunyn-Schmiedeberg's archives of pharmacology 2004;370(5):347-52.
2004: Camarda Valeria; Song Wei; Marzola Erika; Spagnol Martina; Guerrini Remo; Salvadori Severo; Regoli Domenico; Thompson Jonathan P; Rowbotham David J; Behm David J; Douglas Stephen A; Calo' Girolamo; Lambert David G
Urantide mimics urotensin-II induced calcium release in cells expressing recombinant UT receptors.
European journal of pharmacology 2004;498(1-3):83-6.
2004: D'Ursi Anna M; Armenante Maria R; Guerrini Remo; Salvadori Severo; Sorrentino Giuseppe; Picone Delia
Solution structure of amyloid beta-peptide (25-35) in different media.
Journal of medicinal chemistry 2004;47(17):4231-8.
2004: Marti Matteo; Mela Flora; Veronesi Carlo; Guerrini Remo; Salvadori Severo; Federici Mauro; Mercuri Nicola B; Rizzi Anna; Franchi Gianfranco; Beani Lorenzo; Bianchi Clementina; Morari Michele
Blockade of nociceptin/orphanin FQ receptor signaling in rat substantia nigra pars reticulata stimulates nigrostriatal dopaminergic transmission and motor behavior.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2004;24(30):6659-66.
2004: Balboni Gianfranco; Salvadori Severo; Guerrini Remo; Negri Lucia; Giannini Elisa; Bryant Sharon D; Jinsmaa Yunden; Lazarus Lawrence H
Direct influence of C-terminally substituted amino acids in the Dmt-Tic pharmacophore on delta-opioid receptor selectivity and antagonism.
Journal of medicinal chemistry 2004;47(16):4066-71.
2004: Broccardo Maria; Guerrini Remo; Petrella Carla; Improta Giovanna
Gastrointestinal effects of intracerebroventricularly injected nociceptin/orphaninFQ in rats.
Peptides 2004;25(6):1013-20.
2004: Gavioli E C; Vaughan C W; Marzola G; Guerrini R; Mitchell V A; Zucchini S; De Lima T C M; Rae G A; Salvadori S; Regoli D; Calo' G
Antidepressant-like effects of the nociceptin/orphanin FQ receptor antagonist UFP-101: new evidence from rats and mice.
Naunyn-Schmiedeberg's archives of pharmacology 2004;369(6):547-53.
2004: Guerrini R; Carra' G; Calo' G; Trapella C; Marzola E; Rizzi D; Regoli D; Salvadori S
Nonpeptide/peptide chimeric ligands for the nociceptin/orphanin FQ receptor: design, synthesis and in vitro pharmacological activity.
The journal of peptide research : official journal of the American Peptide Society 2004;63(6):477-84.
2004: Au Yunghan; Atkinson R Andrew; Guerrini Remo; Kelly Geoff; Joseph Catherine; Martin Steven R; Muskett Frederick W; Pallavicini Alberto; Faulkner Georgine; Pastore Annalisa
Solution structure of ZASP PDZ domain; implications for sarcomere ultrastructure and enigma family redundancy.
Structure (London, England : 1993) 2004;12(4):611-22.
2004: Johnson Emma E; McDonald John; Nicol Beverley; Guerrini Remo; Lambert David G
Functional coupling of the nociceptin/orphanin FQ receptor in dog brain membranes.
Brain research 2004;1003(1-2):18-25.
2004: Belosi Barbara; Gaggelli Elena; Guerrini Remo; Kozlowski Henryk; Luczkowski Marek; Mancini Francesca M; Remelli Maurizio; Valensin Daniela; Valensin Gianni
Copper binding to the neurotoxic peptide PrP106-126: thermodynamic and structural studies.
Chembiochem : a European journal of chemical biology 2004;5(3):349-59.
2003: Balboni Gianfranco; Salvadori Severo; Guerrini Remo; Negri Lucia; Giannini Elisa; Bryant Sharon D; Jinsmaa Yunden; Lazarus Lawrence H
Synthesis and opioid activity of N,N-dimethyl-Dmt-Tic-NH-CH(R)-R' analogues: acquisition of potent delta antagonism.
Bioorganic & medicinal chemistry 2003;11(24):5435-41.
2003: Kitayama M; Barnes T A; Carra G; McDonald J; Calo G; Guerrini R; Rowbotham D J; Smith G; Lambert D G
Pharmacological profile of the cyclic nociceptin/orphanin FQ analogues c[Cys10,14]N/OFQ(1-14)NH2 and c[Nphe1,Cys10,14]N/OFQ(1-14)NH2.
Naunyn-Schmiedeberg's archives of pharmacology 2003;368(6):528-37.
2003: Johnson Emma E; Gibson Helen; Nicol Beverley; Zanzinger Johannes; Widdowson Peter; Hawthorn Mark; Toth Géza; Farkas Judit; Guerrini Remo; Lambert David G
Characterization of nociceptin/orphanin FQ binding sites in dog brain membranes.
Anesthesia and analgesia 2003;97(3):741-7.
2003: Wright K E; McDonald J; Barnes T A; Rowbotham D J; Guerrini R; Calo' G; Lambert D G
Assessment of the activity of a novel nociceptin/orphanin FQ analogue at recombinant human nociceptin/orphanin FQ receptors expressed in Chinese hamster ovary cells.
Neuroscience letters 2003;346(3):145-8.
2003: Gavioli E C; Marzola G; Guerrini R; Bertorelli R; Zucchini S; De Lima T C M; Rae G A; Salvadori S; Regoli D; Calo G
Blockade of nociceptin/orphanin FQ-NOP receptor signalling produces antidepressant-like effects: pharmacological and genetic evidences from the mouse forced swimming test.
The European journal of neuroscience 2003;17(9):1987-90.
2003: Tognetto Michele; D'Andrea Michael R; Trevisani Marcello; Guerrini Remo; Salvadori Severo; Spisani Lorella; Daniele Carlo; Andrade-Gordon Patricia; Geppetti Pierangelo; Harrison Selena
Proteinase-activated receptor-1 (PAR-1) activation contracts the isolated human renal artery in vitro.
British journal of pharmacology 2003;139(1):21-7.
2003: Lazzeri Massimo; Calò Girolamo; Spinelli Michele; Guerrini Remo; Salvadori Severo; Beneforti Patrizia; Sandri Sandro; Regoli Domenico; Turini Damiano
Urodynamic effects of intravesical nociceptin/orphanin FQ in neurogenic detrusor overactivity: a randomized, placebo-controlled, double-blind study.
Urology 2003;61(5):946-50.
2003: Hashiba Eiji; Hirota Kazuyoshi; Kudo Tsuyoshi; Calo' Girolamo; Guerrini Remo; Matsuki Akitomo
Effects of nociceptin/orphanin FQ receptor ligands on blood pressure, heart rate, and plasma catecholamine concentrations in guinea pigs.
Naunyn-Schmiedeberg's archives of pharmacology 2003;367(4):342-7.
2003: McDonald J; Calo G; Guerrini R; Lambert D G
UFP-101, a high affinity antagonist for the nociceptin/orphanin FQ receptor: radioligand and GTPgamma(35)S binding studies.
Naunyn-Schmiedeberg's archives of pharmacology 2003;367(2):183-7.
2003: Guerrini Remo; Rizzi Daniela; Zucchini Marina; Tomatis Roberto; Regoli Domenico; Calo' Girolamo; Salvadori Severo
Nociceptin/Orphanin FQ(1-13)NH2 analogues modified in the Phe1-Gly2 peptide bond.
Bioorganic & medicinal chemistry letters 2003;13(3):365-8.
2003: Marti Matteo; Stocchi Sara; Paganini Francesca; Mela Flora; De Risi Carmela; Calo' Girolamo; Guerrini Remo; Barnes Timothy A; Lambert David G; Beani Lorenzo; Bianchi Clementina; Morari Michele
Pharmacological profiles of presynaptic nociceptin/orphanin FQ receptors modulating 5-hydroxytryptamine and noradrenaline release in the rat neocortex.
British journal of pharmacology 2003;138(1):91-8.
2002: Balboni Gianfranco; Salvadori Severo; Guerrini Remo; Negri Lucia; Giannini Elisa; Jinsmaa Yunden; Bryant Sharon D; Lazarus Lawrence H
Potent delta-opioid receptor agonists containing the Dmt-Tic pharmacophore.
Journal of medicinal chemistry 2002;45(25):5556-63.
2002: Bryant Sharon D; George Clifford; Flippen-Anderson Judith L; Deschamps Jeffrey R; Salvadori Severo; Balboni Gianfranco; Guerrini Remo; Lazarus Lawrence H
Crystal structures of dipeptides containing the Dmt-Tic pharmacophore.
Journal of medicinal chemistry 2002;45(25):5506-13.
2002: Crescenzi Orlando; Tomaselli Simona; Guerrini Remo; Salvadori Severo; D'Ursi Anna M; Temussi Piero Andrea; Picone Delia
Solution structure of the Alzheimer amyloid beta-peptide (1-42) in an apolar microenvironment. Similarity with a virus fusion domain.
European journal of biochemistry / FEBS 2002;269(22):5642-8.
2002: Camarda Valeria; Guerrini Remo; Kostenis Evi; Rizzi Anna; Calò Girolamo; Hattenberger Almut; Zucchini Marina; Salvadori Severo; Regoli Domenico
A new ligand for the urotensin II receptor.
British journal of pharmacology 2002;137(3):311-4.
2002: Amodeo Pietro; Guerrini Remo; Picone Delia; Salvadori Severo; Spadaccini Roberta; Tancredi Teodorico; Temussi Piero A
Solution structure of nociceptin peptides.
Journal of peptide science : an official publication of the European Peptide Society 2002;8(9):497-509.
2002: Hashimoto Yoshio; Calo' Girolamo; Guerrini Remo; Smith Graham; Lambert David G
Effects of chronic nociceptin/orphanin FQ exposure on cAMP accumulation and receptor density in Chinese hamster ovary cells expressing human nociceptin/orphanin FQ receptors.
European journal of pharmacology 2002;449(1-2):17-22.
2002: Gavioli Elaine C; Rae Giles A; Calo' Girolamo; Guerrini Remo; De Lima Thereza C M
Central injections of nocistatin or its C-terminal hexapeptide exert anxiogenic-like effect on behaviour of mice in the plus-maze test.
British journal of pharmacology 2002;136(5):764-72.
2002: Rizzi Anna; Salis Maria Bonaria; Ciccocioppo Roberto; Marzola Giuliano; Bigoni Raffaella; Guerrini Remo; Massi Maurizio; Madeddu Paolo; Salvadori Severo; Regoli Domenico; Calo' Girolamo
Pharmacological characterisation of [(pX)Phe4]nociceptin(1-13)NH2 analogues. 2. In vivo studies.
Naunyn-Schmiedeberg's archives of pharmacology 2002;365(6):450-6.
2002: Bigoni Raffaella; Rizzi Daniela; Rizzi Anna; Camarda Valeria; Guerrini Remo; Lambert David G; Hashiba Eiji; Berger Hartmut; Salvadori Severo; Regoli Domenico; Calo' Girolamo
Pharmacological characterisation of [(pX)Phe4]nociceptin(1-13)amide analogues. 1. In vitro studies.
Naunyn-Schmiedeberg's archives of pharmacology 2002;365(6):442-9.
2002: Camarda V; Rizzi A; Calo G; Guerrini R; Salvadori S; Regoli D
Pharmacological profile of hemokinin 1: a novel member of the tachykinin family.
Life sciences 2002;71(4):363-70.
2002: McDonald John; Barnes Timothy A; Calo Girolamo; Guerrini Remo; Rowbotham David J; Lambert David G
Effects of [(pF)Phe(4)]nociceptin/orphanin FQ-(1-13)NH(2) on GTPgamma(35)S binding and cAMP formation in Chinese hamster ovary cells expressing the human nociceptin/orphanin FQ receptor.
European journal of pharmacology 2002;443(1-3):7-12.
2002: Calo Girolamo; Rizzi Anna; Rizzi Daniela; Bigoni Raffaella; Guerrini Remo; Marzola Giuliano; Marti Matteo; McDonald John; Morari Michele; Lambert David G; Salvadori Severo; Regoli Domenico
[Nphe1,Arg14,Lys15]nociceptin-NH2, a novel potent and selective antagonist of the nociceptin/orphanin FQ receptor.
British journal of pharmacology 2002;136(2):303-11.
2002: Calo' Girolamo; Rizzi Anna; Bigoni Raffaella; Guerrini Remo; Salvadori Severo; Regoli Domenico
Pharmacological profile of nociceptin/orphanin FQ receptors.
Clinical and experimental pharmacology & physiology 2002;29(3):223-8.
2002: Politou Anastasia S; Spadaccini Roberta; Joseph Catherine; Brannetti Barbara; Guerrini Remo; Helmer-Citterich Manuela; Salvadori Severo; Temussi Piero Andrea; Pastore Annalisa
The SH3 domain of nebulin binds selectively to type II peptides: theoretical prediction and experimental validation.
Journal of molecular biology 2002;316(2):305-15.
2002: Chiou Lih-Chu; Fan Shu-Huai; Guerrini Remo; Caló Girolamo
[Nphe(1)]N/OFQ-(1-13)-NH(2) is a competitive and selective antagonist at nociceptin/orphanin FQ receptors mediating K(+) channel activation in rat periaqueductal gray slices.
Neuropharmacology 2002;42(2):246-52.
2002: Xu Isabella S; Grass Stefan; Calo Girolamo; Guerrini Remo; Wiesenfeld-Hallin Zsuzsanna; Xu Xiao-Jun
Intrathecal [Nphe1]nociceptin( 1-13)NH2 selectively reduces the spinal inhibitory effect of nociceptin.
Life sciences 2002;70(10):1151-7.
2002: Ciccocioppo Roberto; Polidori Carlo; Antonelli Lorena; Salvadori Severo; Guerrini Remo; Massi Maurizio
Pharmacological characterization of the nociceptin receptor which mediates reduction of alcohol drinking in rats.
Peptides 2002;23(1):117-25.
2002: Balboni Gianfranco; Guerrini Remo; Salvadori Severo; Bianchi Clementina; Rizzi Daniela; Bryant Sharon D; Lazarus Lawrence H
Evaluation of the Dmt-Tic pharmacophore: conversion of a potent delta-opioid receptor antagonist into a potent delta agonist and ligands with mixed properties.
Journal of medicinal chemistry 2002;45(3):713-20.
2002: Rizzi Daniela; Rizzi Anna; Bigoni Raffaella; Camarda Valeria; Marzola Giuliano; Guerrini Remo; De Risi Carmela; Regoli Domenico; Calo' Girolamo
[Arg(14),Lys(15)]nociceptin, a highly potent agonist of the nociceptin/orphanin FQ receptor: in vitro and in vivo studies.
The Journal of pharmacology and experimental therapeutics 2002;300(1):57-63.
2002: Marti M; Guerrini R; Beani L; Bianchi C; Morari M
Nociceptin/orphanin FQ receptors modulate glutamate extracellular levels in the substantia nigra pars reticulata. A microdialysis study in the awake freely moving rat.
Neuroscience 2002;112(1):153-60.
2001: Di Giannuario A; Rizzi A; Pieretti S; Guerrini R; Bertorelli R; Salvadori S; Regoli D; Calo G
Studies on the antinociceptive effect of [Nphe1]nociceptin(1-13)NH2 in mice.
Neuroscience letters 2001;316(1):25-8.
2001: Lazzeri M; Calò G; Spinelli M; Guerrini R; Beneforti P; Sandri S; Zanollo A; Regoli D; Turini D
Urodynamic and clinical evidence of acute inhibitory effects of intravesical nociceptin/orphanin FQ on detrusor overactivity in humans: a pilot study.
The Journal of urology 2001;166(6):2237-40.
2001: Guerrini R; Caló G; Bigoni R; Rizzi D; Rizzi A; Zucchini M; Varani K; Hashiba E; Lambert D G; Toth G; Borea P A; Salvadori S; Regoli D
Structure-activity studies of the Phe(4) residue of nociceptin(1-13)-NH(2): identification of highly potent agonists of the nociceptin/orphanin FQ receptor.
Journal of medicinal chemistry 2001;44(23):3956-64.
2001: Rizzi A; Marzola G; Bigoni R; Guerrini R; Salvadori S; Mogil J S; Regoli D; Calò G
Endogenous nociceptin signaling and stress-induced analgesia.
Neuroreport 2001;12(14):3009-13.
2001: Rizzi D; Bigoni R; Rizzi A; Jenck F; Wichmann J; Guerrini R; Regoli D; Calo G
Effects of Ro 64-6198 in nociceptin/orphanin FQ-sensitive isolated tissues.
Naunyn-Schmiedeberg's archives of pharmacology 2001;363(5):551-5.
2001: Lovekamp T; Cooper P S; Hardison J; Bryant S D; Guerrini R; Balboni G; Salvadori S; Lazarus L H
Inhibition of human multidrug resistance P-glycoprotein 1 by analogues of a potent delta-opioid antagonist.
Brain research 2001;902(1):131-4.
2001: Conato C; Gavioli R; Guerrini R; Kozlowski H; Mlynarz P; Pasti C; Pulidori F; Remelli M
Copper complexes of glycyl-histidyl-lysine and two of its synthetic analogues: chemical behaviour and biological activity.
Biochimica et biophysica acta 2001;1526(2):199-210.
2001: Okawa H; Kudo M; Kudo T; Guerrini R; Lambert D G; Kushikata T; Yoshida H; Matsuki A
Effects of nociceptinNH2 and [Nphe1]nociceptin(1-13)NH2 on rat brain noradrenaline release in vivo and in vitro.
Neuroscience letters 2001;303(3):173-6.
2001: Bigoni R; Calo G; Guerrini R; Strupish J W; Rowbotham D J; Lambert D G
Effects of nociceptin and endomorphin 1 on the electrically stimulated human vas deferens.
British journal of clinical pharmacology 2001;51(4):355-8.
2001: Guerrini R; Calo' G; Bigoni R; Rizzi D; Regoli D; Salvadori S
Structure-activity relationship of [Nphe1]-NC-(1-13)-NH2, a pure and selective nociceptin/orphanin FQ receptor antagonist.
The journal of peptide research : official journal of the American Peptide Society 2001;57(3):215-22.
2001: Rizzi A; Bigoni R; Marzola G; Guerrini R; Salvadori S; Regoli D; Calo' G
Characterization of the locomotor activity-inhibiting effect of nociceptin/orphanin FQ in mice.
Naunyn-Schmiedeberg's archives of pharmacology 2001;363(2):161-5.
2001: Hashiba E; Harrison C; Galo' G; Guerrini R; Rowbotham D J; Smith G; Lambert D G
Characterisation and comparison of novel ligands for the nociceptin/orphanin FQ receptor.
Naunyn-Schmiedeberg's archives of pharmacology 2001;363(1):28-33.
2000: Santagada V; Balboni G; Caliendo G; Guerrini R; Salvadori S; Bianchi C; Bryant S D; Lazarus L H
Assessment of substitution in the second pharmacophore of Dmt-Tic analogues.
Bioorganic & medicinal chemistry letters 2000;10(24):2745-8.
2000: Balboni G; Salvadori S; Guerrini R; Bianchi C; Santagada V; Calliendo G; Bryant S D; Lazarus L H
Opioid pseudopeptides containing heteroaromatic or heteroaliphatic nuclei.
Peptides 2000;21(11):1663-71.
2000: Tognetto M; Trevisani M; Maggiore B; Navarra G; Turini A; Guerrini R; Bunnett N W; Geppetti P; Harrison S
Evidence that PAR-1 and PAR-2 mediate prostanoid-dependent contraction in isolated guinea-pig gallbladder.
British journal of pharmacology 2000;131(4):689-94.
2000: Rizzi A; Bigoni R; Marzola G; Guerrini R; Salvadori S; Regoli D; Calo G
The nociceptin/orphanin FQ receptor antagonist, [Nphe1]NC(1-13)NH2, potentiates morphine analgesia.
Neuroreport 2000;11(11):2369-72.
2000: Calo' G; Bigoni R; Rizzi A; Guerrini R; Salvadori S; Regoli D
Nociceptin/orphanin FQ receptor ligands.
Peptides 2000;21(7):935-47.
2000: Guerrini R; Calo' G; Rizzi A; Bigoni R; Rizzi D; Regoli D; Salvadori S
Structure-activity relationships of nociceptin and related peptides: comparison with dynorphin A.
Peptides 2000;21(7):923-33.
2000: Guerrini R; Caló G; Bigoni R; Rizzi A; Varani K; Toth G; Gessi S; Hashiba E; Hashimoto Y; Lambert D G; Borea P A; Tomatis R; Salvadori S; Regoli D
Further studies on nociceptin-related peptides: discovery of a new chemical template with antagonist activity on the nociceptin receptor.
Journal of medicinal chemistry 2000;43(15):2805-13.
2000: Bigoni R; Calo' G; Rizzi A; Guerrini R; De Risi C; Hashimoto Y; Hashiba E; Lambert D G; Regoli D
In vitro characterization of J-113397, a non-peptide nociceptin/orphanin FQ receptor antagonist.
Naunyn-Schmiedeberg's archives of pharmacology 2000;361(5):565-8.
2000: Sbrenna S; Marti M; Morari M; Calo' G; Guerrini R; Beani L; Bianchi C
Modulation of 5-hydroxytryptamine efflux from rat cortical synaptosomes by opioids and nociceptin.
British journal of pharmacology 2000;130(2):425-33.
2000: Ricciardolo F L; Steinhoff M; Amadesi S; Guerrini R; Tognetto M; Trevisani M; Creminon C; Bertrand C; Bunnett N W; Fabbri L M; Salvadori S; Geppetti P
Presence and bronchomotor activity of protease-activated receptor-2 in guinea pig airways.
American journal of respiratory and critical care medicine 2000;161(5):1672-80.
2000: Calo' G; Guerrini R; Rizzi A; Salvadori S; Regoli D
Pharmacology of nociceptin and its receptor: a novel therapeutic target.
British journal of pharmacology 2000;129(7):1261-83.
2000: Polidori C; Calo G; Ciccocioppo R; Guerrini R; Regoli D; Massi M
Pharmacological characterization of the nociceptin receptor mediating hyperphagia: identification of a selective antagonist.
Psychopharmacology 2000;148(4):430-7.
2000: Calo' G; Guerrini R; Bigoni R; Rizzi A; Marzola G; Okawa H; Bianchi C; Lambert D G; Salvadori S; Regoli D
Characterization of [Nphe(1)]nociceptin(1-13)NH(2), a new selective nociceptin receptor antagonist.
British journal of pharmacology 2000;129(6):1183-93.
2000: Crescenzi O; Guerrini R; Picone D; Salvadori S; Tancredi T; Temussi P A
Solution structure of nocistatin, a new peptide analgesic.
Biopolymers 2000;53(3):257-64.
2000: Hashimoto Y; Caló G; Guerrini R; Smith G; Lambert D G
Antagonistic effects of [Nphe1]nociceptin(1-13)NH2 on nociceptin receptor mediated inhibition of cAMP formation in Chinese hamster ovary cells stably expressing the recombinant human nociceptin receptor.
Neuroscience letters 2000;278(1-2):109-12.
1999: Rizzi A; Bigoni R; Caló G; Guerrini R; Salvadori S; Regoli D
[Nphe(1)]nociceptin-(1-13)-NH(2) antagonizes nociceptin effects in the mouse colon.
European journal of pharmacology 1999;385(2-3):R3-5.
1999: Salvadori S; Guerrini R; Balboni G; Bianchi C; Bryant S D; Cooper P S; Lazarus L H
Further studies on the Dmt-Tic pharmacophore: hydrophobic substituents at the C-terminus endow delta antagonists to manifest mu agonism or mu antagonism.
Journal of medicinal chemistry 1999;42(24):5010-9.
1999: Sbrenna S; Marti M; Morari M; Calo G; Guerrini R; Beani L; Bianchi C
L-glutamate and gamma-aminobutyric acid efflux from rat cerebrocortical synaptosomes: modulation by kappa- and mu- but not delta- and opioid receptor like-1 receptors.
The Journal of pharmacology and experimental therapeutics 1999;291(3):1365-71.
1999: Salvadori S; Guerrini R; Calo G; Regoli D
Structure-activity studies on nociceptin/orphanin FQ: from full agonist, to partial agonist, to pure antagonist.
Farmaco (Società chimica italiana : 1989) 1999;54(11-12):810-25.
1999: Varani K; Rizzi A; Calo G; Bigoni R; Toth G; Guerrini R; Gessi S; Salvadori S; Borea P A; Regoli D
Pharmacology of [Tyr1]nociceptin analogs: receptor binding and bioassay studies.
Naunyn-Schmiedeberg's archives of pharmacology 1999;360(3):270-7.
1999: Micheletti F; Guerrini R; Formentin A; Canella A; Marastoni M; Bazzaro M; Tomatis R; Traniello S; Gavioli R
Selective amino acid substitutions of a subdominant Epstein-Barr virus LMP2-derived epitope increase HLA/peptide complex stability and immunogenicity: implications for immunotherapy of Epstein-Barr virus-associated malignancies.
European journal of immunology 1999;29(8):2579-89.
1999: Okawa H; Nicol B; Bigoni R; Hirst R A; Calo G; Guerrini R; Rowbotham D J; Smart D; McKnight A T; Lambert D G
Comparison of the effects of [Phe1psi(CH2-NH)Gly2]nociceptin(1-13)NH2 in rat brain, rat vas deferens and CHO cells expressing recombinant human nociceptin receptors.
British journal of pharmacology 1999;127(1):123-30.
1999: Bigoni R; Giuliani S; Calo' G; Rizzi A; Guerrini R; Salvadori S; Regoli D; Maggi C A
Characterization of nociceptin receptors in the periphery: in vitro and in vivo studies.
Naunyn-Schmiedeberg's archives of pharmacology 1999;359(3):160-7.
1999: Marastoni M; Guerrini R; Balboni G; Salvadori S; Fantin G; Fogagnolo M; Lazarus L H; Tomatis R
Opioid deltorphin C analogues containing cis- or trans-2- or 3- or 4-aminocyclohexanecarboxylic acid residues.
Arzneimittel-Forschung 1999;49(1):6-12.
1999: Reali E; Guerrini R; Marastoni M; Tomatis R; Masucci M G; Traniello S; Gavioli R
A single specific amino acid residue in peptide antigens is sufficient to activate memory CTL: potential role of cross-reactive peptides in memory T cell maintenance.
Journal of immunology (Baltimore, Md. : 1950) 1999;162(1):106-13.
1999: Rizzi A; Calò G; Trevisani M; Tognetto M; Fabbri L; Mapp C; Guerrini R; Salvadori S; Regoli D; Geppetti P
Nociceptin receptor activation inhibits tachykinergic non adrenergic non cholinergic contraction of guinea pig isolated bronchus.
Life sciences 1999;64(13):PL157-63.
1998: Varani K; Calo G; Rizzi A; Merighi S; Toth G; Guerrini R; Salvadori S; Borea P A; Regoli D
Nociceptin receptor binding in mouse forebrain membranes: thermodynamic characteristics and structure activity relationships.
British journal of pharmacology 1998;125(7):1485-90.
1998: Calò G; Rizzi A; Marzola G; Guerrini R; Salvadori S; Beani L; Regoli D; Bianchi C
Pharmacological characterization of the nociceptin receptor mediating hyperalgesia in the mouse tail withdrawal assay.
British journal of pharmacology 1998;125(2):373-8.
1998: Calo' G; Guerrini R; Bigoni R; Rizzi A; Bianchi C; Regoli D; Salvadori S
Structure-activity study of the nociceptin(1-13)-NH2 N-terminal tetrapeptide and discovery of a nociceptin receptor antagonist.
Journal of medicinal chemistry 1998;41(18):3360-6.
1998: Bondanelli M; Ambrosio M R; Franceschetti P; Guerrini R; Valentini A; degli Uberti E C
Effect of delta-opioid receptor agonist deltorphin on circulating concentrations of luteinizing hormone and follicle stimulating hormone in healthy fertile women.
Human reproduction (Oxford, England) 1998;13(5):1159-62.
1998: Guerrini R; Capasso A; Marastoni M; Bryant S D; Cooper P S; Lazarus L H; Temussi P A; Salvadori S
Rational design of dynorphin A analogues with delta-receptor selectivity and antagonism for delta- and kappa-receptors.
Bioorganic & medicinal chemistry 1998;6(1):57-62.
1998: Guerrini R; Calo G; Rizzi A; Bigoni R; Bianchi C; Salvadori S; Regoli D
A new selective antagonist of the nociceptin receptor.
British journal of pharmacology 1998;123(2):163-5.
1998: Gavioli R; Guerrini R; Masucci M G; Tomatis R; Traniello S; Marastoni M
High structural side chain specificity required at the second position of immunogenic peptides to obtain stable MHC/peptide complexes.
FEBS letters 1998;421(2):95-9.
1997: Capasso A; Amodeo P; Balboni G; Guerrini R; Lazarus L H; Temussi P A; Salvadori S
Design of mu selective opioid dipeptide antagonists.
FEBS letters 1997;417(1):141-4.
1997: Salvadori S; Balboni G; Guerrini R; Tomatis R; Bianchi C; Bryant S D; Cooper P S; Lazarus L H
Evolution of the Dmt-Tic pharmacophore: N-terminal methylated derivatives with extraordinary delta opioid antagonist activity.
Journal of medicinal chemistry 1997;40(19):3100-8.
1997: Tomatis R; Marastoni M; Balboni G; Guerrini R; Capasso A; Sorrentino L; Santagada V; Caliendo G; Lazarus L H; Salvadori S
Synthesis and pharmacological activity of deltorphin and dermorphin-related glycopeptides.
Journal of medicinal chemistry 1997;40(18):2948-52.
1997: Bryant S D; Guerrini R; Salvadori S; Bianchi C; Tomatis R; Attila M; Lazarus L H
Helix-inducing alpha-aminoisobutyric acid in opioid mimetic deltorphin C analogues.
Journal of medicinal chemistry 1997;40(16):2579-87.
1997: Crescenzi O; Fraternali F; Picone D; Tancredi T; Balboni G; Guerrini R; Lazarus L H; Salvadori S; Temussi P A
Design and solution structure of a partially rigid opioid antagonist lacking the basic center--models of antagonism.
European journal of biochemistry / FEBS 1997;247(1):66-73.
1997: Calò G; Rizzi A; Bodin M; Neugebauer W; Salvadori S; Guerrini R; Bianchi C; Regoli D
Pharmacological characterization of nociceptin receptor: an in vitro study.
Canadian journal of physiology and pharmacology 1997;75(6):713-8.
1997: Guerrini R; Calo G; Rizzi A; Bianchi C; Lazarus L H; Salvadori S; Temussi P A; Regoli D
Address and message sequences for the nociceptin receptor: a structure-activity study of nociceptin-(1-13)-peptide amide.
Journal of medicinal chemistry 1997;40(12):1789-93.
1997: Salvadori S; Picone D; Tancredi T; Guerrini R; Spadaccini R; Lazarus L H; Regoli D; Temussi P A
Solution conformation of nociceptin.
Biochemical and biophysical research communications 1997;233(3):640-3.
1997: Bryant S D; Balboni G; Guerrini R; Salvadori S; Tomatis R; Lazarus L H
Opioid diketopiperazines: refinement of the delta opioid antagonist pharmacophore.
Biological chemistry 1997;378(2):107-14.
1997: Balboni G; Guerrini R; Salvadori S; Tomatis R; Bryant S D; Bianchi C; Attila M; Lazarus L H
Opioid diketopiperazines: synthesis and activity of a prototypic class of opioid antagonists.
Biological chemistry 1997;378(1):19-29.
1996: Crescenzi O; Amodeo P; Cavicchioni G; Guerrini R; Picone D; Salvadori S; Tancredi T; Temussi P A
Delta-selective opioid peptides containing a single aromatic residue in the message domain: an NMR conformational analysis.
Journal of peptide science : an official publication of the European Peptide Society 1996;2(5):290-308.
1996: Calò G; Rizzi A; Bogoni G; Neugebauer V; Salvadori S; Guerrini R; Bianchi C; Regoli D
The mouse vas deferens: a pharmacological preparation sensitive to nociceptin.
European journal of pharmacology 1996;311(1):R3-5.
1996: Reali E; Guerrini R; Moretti S; Spisani S; Lanza F; Tomatis R; Traniello S; Gavioli R
Polymorphonuclear neutrophils pulsed with synthetic peptides efficiently activate memory cytotoxic T lymphocytes.
Journal of leukocyte biology 1996;60(2):207-13.
1996: Reali E; Guerrini R; Giori B; Borghi M; Marastoni M; Tomatis R; Traniello S; Masucci M G; Gavioli R
Activation of epitope-specific memory cytotoxic T lymphocyte responses by synthetic peptides.
Clinical and experimental immunology 1996;105(2):369-75.
1996: Guerrini R; Capasso A; Sorrentino L; Anacardio R; Bryant S D; Lazarus L H; Attila M; Salvadori S
Opioid receptor selectivity alteration by single residue replacement: synthesis and activity profile of [Dmt1]deltorphin B.
European journal of pharmacology 1996;302(1-3):37-42.
1996: Breveglieri A; Guerrini R; Salvadori S; Bianchi C; Bryant S D; Attila M; Lazarus L H
Design and synthesis of 1-aminocycloalkane-1-carboxylic acid-substituted deltorphin analogues: unique delta and mu opioid activity in modified peptides.
Journal of medicinal chemistry 1996;39(3):773-80.
1996: Capasso A; Guerrini R; Balboni G; Sorrentino L; Temussi P; Lazarus L H; Bryant S D; Salvadori S
Dmt-Tic-OH a highly selective and potent delta-opioid dipeptide receptor antagonist after systemic administration in the mouse.
Life sciences 1996;59(8):PL93-8.
1995: Amodeo P; Balboni G; Crescenzi O; Guerrini R; Picone D; Salvadori S; Tancredi T; Temussi P A
Conformational analysis of potent and very selective delta opioid dipeptide antagonists.
FEBS letters 1995;377(3):363-7.
1995: Salvadori S; Attila M; Balboni G; Bianchi C; Bryant S D; Crescenzi O; Guerrini R; Picone D; Tancredi T; Temussi P A
Delta opioidmimetic antagonists: prototypes for designing a new generation of ultraselective opioid peptides.
Molecular medicine (Cambridge, Mass.) 1995;1(6):678-89.
1995: Capasso S; Sica F; Mazzarella L; Balboni G; Guerrini R; Salvadori S
Acid catalysis in the formation of dioxopiperazines from peptides containing tetrahydroisoquinoline-3-carboxylic acid at position 2.
International journal of peptide and protein research 1995;45(6):567-73.
1995: Gavioli R; Zhang Q J; Marastoni M; Guerrini R; Reali E; Tomatis R; Masucci M G; Traniello S
Effect of anchor residue modifications on the stability of HLA-A11/peptide complexes.
Biochemical and biophysical research communications 1995;206(1):8-14.
1994: Tancredi T; Salvadori S; Amodeo P; Picone D; Lazarus L H; Bryant S D; Guerrini R; Marzola G; Temussi P A
Conversion of enkephalin and dermorphin into delta-selective opioid antagonists by single-residue substitution.
European journal of biochemistry / FEBS 1994;224(1):241-7.
1994: Bryant S D; Attila M; Salvadori S; Guerrini R; Lazarus L H
Molecular dynamics conformations of deltorphin analogues advocate delta opioid binding site models.
Peptide research 1994;7(4):175-84.
1994: Temussi P A; Salvadori S; Amodeo P; Bianchi C; Guerrini R; Tomatis R; Lazarus L H; Picone D; Tancredi T
Selective opioid dipeptides.
Biochemical and biophysical research communications 1994;198(3):933-9.
1992: Salvadori S; Guerrini R; Borea P A; Tomatis R
Synthesis and pharmacological activity of the N-terminal dermorphin tetrapeptide analogs with CH2-NH peptide bond isosteres.
International journal of peptide and protein research 1992;40(5):437-44.

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