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William Guggino

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Co-Publications
Name
28
Zeitlin, Pamela
27
Guggino, Sandra
25
Cutting, Garry
25
Schwiebert, Erik
18
Flotte, Terence
16
Morales, Marcelo
15
Agre, Peter
12
Carter, Barbara
11
Stanton, Bruce
9
Montrose-Rafizadeh, C
9
Devidas, Shreenivas
9
Egan, Marie
8
Wright, Jerry
7
Cheng, Jie
7
Cebotaru, Liudmila

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Publications

TOP 3
Woodward Owen M; Köttgen Anna; Coresh Josef; Boerwinkle Eric; Guggino William B; Köttgen Michael
Identification of a urate transporter, ABCG2, with a common functional polymorphism causing gout.
Liang Lihua; MacDonald Kelvin; Schwiebert Erik M; Zeitlin Pamela L; Guggino William B
Spiperone, identified through compound screening, activates calcium-dependent chloride secretion in the airway.
Krasnov Kristina V; Tzetis Maria; Cheng Jie; Guggino William B; Cutting Garry R
Localization studies of rare missense mutations in cystic fibrosis transmembrane conductance regulator (CFTR) facilitate interpretation of genotype-phenotype relationships.

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All Publications

2009: Woodward Owen M; Köttgen Anna; Coresh Josef; Boerwinkle Eric; Guggino William B; Köttgen Michael
Identification of a urate transporter, ABCG2, with a common functional polymorphism causing gout.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(25):10338-42.
2009: Liang Lihua; MacDonald Kelvin; Schwiebert Erik M; Zeitlin Pamela L; Guggino William B
Spiperone, identified through compound screening, activates calcium-dependent chloride secretion in the airway.
American journal of physiology. Cell physiology 2009;296(1):C131-41.
2008: Krasnov Kristina V; Tzetis Maria; Cheng Jie; Guggino William B; Cutting Garry R
Localization studies of rare missense mutations in cystic fibrosis transmembrane conductance regulator (CFTR) facilitate interpretation of genotype-phenotype relationships.
Human mutation 2008;29(11):1364-72.
2008: Cebotaru Liudmila; Vij Neeraj; Ciobanu Igor; Wright Jerry; Flotte Terence; Guggino William B
Cystic fibrosis transmembrane regulator missing the first four transmembrane segments increases wild type and DeltaF508 processing.
The Journal of biological chemistry 2008;283(32):21926-33.
2008: Wright Jerry; Morales Marcelo M; Sousa-Menzes Jackson; Ornellas Debora; Sipes Jennifer; Cui Yan; Cui Isabelle; Hulamm Phuson; Cebotaru Valeriu; Cebotaru Liudmila; Guggino William B; Guggino Sandra E
Transcriptional adaptation to Clcn5 knockout in proximal tubules of mouse kidney.
Physiological genomics 2008;33(3):341-54.
2008: Lassance Roberta M; Pássaro Caroline P; Martini Sabrina V; Castiglione Raquel C; Gutierrez Tatiana M; Abreu Soraia C; Antunes Mariana A; Xisto Debora G; Cebotaru Liudmila; Petrs-Silva Hilda; Zin Walter A; Guggino William B; Linden Rafael; Rocco Patricia R M; Morales Marcelo M
Does the use of recombinant AAV2 in pulmonary gene therapy damage lung function?
Respiratory physiology & neurobiology 2008;160(1):91-8.
2008: Souza-Menezes Jackson; Tukaye Deepali N; Novaira Horacio Javier; Guggino William B; Morales Marcelo M
Small nuclear RNAs U11 and U12 modulate expression of TNR-CFTR mRNA in mammalian kidneys.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2008;22(1-4):93-100.
2007: Liu Xiaoming; Luo Meihui; Trygg Cyndi; Yan Ziying; Lei-Butters Diana C M; Smith Carolina I; Fischer Anne C; Munson Keith; Guggino William B; Bunnell Bruce A; Engelhardt John F
Biological Differences in rAAV Transduction of Airway Epithelia in Humans and in Old World Non-human Primates.
Molecular therapy : the journal of the American Society of Gene Therapy 2007;15(12):2114-23.
2007: Fischer Anne C; Smith Carolina I; Cebotaru Liudmila; Zhang Xuemei; Askin Frederic B; Wright Jerry; Guggino Sandra E; Adams Robert J; Flotte Terence; Guggino William B
Expression of a truncated cystic fibrosis transmembrane conductance regulator with an AAV5-pseudotyped vector in primates.
Molecular therapy : the journal of the American Society of Gene Therapy 2007;15(4):756-63.
2007: Wolde Michael; Fellows Abigail; Cheng Jie; Kivenson Aleksandr; Coutermarsh Bonita; Talebian Laleh; Karlson Katherine; Piserchio Andrea; Mierke Dale F; Stanton Bruce A; Guggino William B; Madden Dean R
Targeting CAL as a negative regulator of DeltaF508-CFTR cell-surface expression: an RNA interference and structure-based mutagenetic approach.
The Journal of biological chemistry 2007;282(11):8099-109.
2007: Kwon Sang-Ho; Pollard Harvey; Guggino William B
Knockdown of NHERF1 enhances degradation of temperature rescued DeltaF508 CFTR from the cell surface of human airway cells.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2007;20(6):763-72.
2007: Souza-Menezes Jackson; Morales Marcelo M; Tukaye Deepali N; Guggino Sandra E; Guggino William B
Absence of ClC5 in knockout mice leads to glycosuria, impaired renal glucose handling and low proximal tubule GLUT2 protein expression.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2007;20(5):455-64.
2006: Caruso-Neves Celso; Pinheiro Ana Acacia S; Cai Hui; Souza-Menezes Jackson; Guggino William B
PKB and megalin determine the survival or death of renal proximal tubule cells.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(49):18810-5.
2006: Pollard Harvey B; Eidelman Ofer; Jozwik Catherine; Huang Wei; Srivastava Meera; Ji Xia D; McGowan Brighid; Norris Christine Formas; Todo Tsuyoshi; Darling Thomas; Mogayzel Peter J; Zeitlin Pamela L; Wright Jerry; Guggino William B; Metcalf Eleanore; Driscoll William J; Mueller Greg; Paweletz Cloud; Jacobowitz David M
De novo biosynthetic profiling of high abundance proteins in cystic fibrosis lung epithelial cells.
Molecular & cellular proteomics : MCP 2006;5(9):1628-37.
2006: Wright Jerry M; Merlo Christian A; Reynolds Jeffrey B; Zeitlin Pamela L; Garcia Joe G N; Guggino William B; Boyle Michael P
Respiratory epithelial gene expression in patients with mild and severe cystic fibrosis lung disease.
American journal of respiratory cell and molecular biology 2006;35(3):327-36.
2006: Guggino William B; Stanton Bruce A
New insights into cystic fibrosis: molecular switches that regulate CFTR.
Nature reviews. Molecular cell biology 2006;7(6):426-36.
2006: Cai H; Cebotaru V; Wang Y-H; Zhang X-M; Cebotaru L; Guggino S E; Guggino W B
WNK4 kinase regulates surface expression of the human sodium chloride cotransporter in mammalian cells.
Kidney international 2006;69(12):2162-70.
2006: Novaira H J; Ornellas D S; Ortiga-Carvalho T M; Zhang X M; Souza-Menezes J; Guggino S E; Guggino W B; Morales M M
Atrial natriuretic peptide modulates cystic fibrosis transmembrane conductance regulator chloride channel expression in rat proximal colon and human intestinal epithelial cells.
The Journal of endocrinology 2006;189(1):155-65.
2006: van den Hove Marie-France; Croizet-Berger Karine; Jouret François; Guggino Sandra E; Guggino William B; Devuyst Olivier; Courtoy Pierre J
The loss of the chloride channel, ClC-5, delays apical iodide efflux and induces a euthyroid goiter in the mouse thyroid gland.
Endocrinology 2006;147(3):1287-96.
2006: Beitz Eric; Liu Kun; Ikeda Masahiro; Guggino William B; Agre Peter; Yasui Masato
Determinants of AQP6 trafficking to intracellular sites versus the plasma membrane in transfected mammalian cells.
Biology of the cell / under the auspices of the European Cell Biology Organization 2006;98(2):101-9.
2006: Ikeda Masahiro; Fong Peying; Cheng Jie; Boletta Alessandra; Qian Feng; Zhang Xue-Mei; Cai Hui; Germino Gregory G; Guggino William B
A regulatory role of polycystin-1 on cystic fibrosis transmembrane conductance regulator plasma membrane expression.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2006;18(1-3):9-20.
2006: Boyle Michael P; Enke Raymond A; Reynolds Jeffrey B; Mogayzel Peter J; Guggino William B; Zeitlin Pamela L
Membrane-associated heparan sulfate is not required for rAAV-2 infection of human respiratory epithelia.
Virology journal 2006;3():29.
2005: Li Yun; Wright Jerry M; Qian Feng; Germino Gregory G; Guggino William B
Polycystin 2 interacts with type I inositol 1,4,5-trisphosphate receptor to modulate intracellular Ca2+ signaling.
The Journal of biological chemistry 2005;280(50):41298-306.
2005: Caruso-Neves Celso; Kwon Sang-Ho; Guggino William B
Albumin endocytosis in proximal tubule cells is modulated by angiotensin II through an AT2 receptor-mediated protein kinase B activation.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(48):17513-8.
2005: Wang Yinghong; Cai Hui; Cebotaru Liudmila; Hryciw Deanne H; Weinman Edward J; Donowitz Mark; Guggino Sandra E; Guggino William B
ClC-5: role in endocytosis in the proximal tubule.
American journal of physiology. Renal physiology 2005;289(4):F850-62.
2005: Flotte Terence R; Schwiebert Erik M; Zeitlin Pamela L; Carter Barrie J; Guggino William B
Correlation between DNA transfer and cystic fibrosis airway epithelial cell correction after recombinant adeno-associated virus serotype 2 gene therapy.
Human gene therapy 2005;16(8):921-8.
2005: Cebotaru Valeriu; Kaul Sadhana; Devuyst Olivier; Cai Hui; Racusen Lorraine; Guggino William B; Guggino Sandra E
High citrate diet delays progression of renal insufficiency in the ClC-5 knockout mouse model of Dent's disease.
Kidney international 2005;68(2):642-52.
2005: Hara-Chikuma Mariko; Wang Yinghong; Guggino Sandra E; Guggino William B; Verkman A S
Impaired acidification in early endosomes of ClC-5 deficient proximal tubule.
Biochemical and biophysical research communications 2005;329(3):941-6.
2005: Rebelo Maria Alice P; Tostes Vera; Araújo Nordeval C; Martini Sabrina V; Botelho Bruno F; Guggino William B; Morales Marcelo M
Screening for CLCN5 mutation in renal calcium stone formers patients.
Anais da Academia Brasileira de Ciências 2005;77(1):95-101.
2005: Cheng Jie; Wang Hua; Guggino William B
Regulation of cystic fibrosis transmembrane regulator trafficking and protein expression by a Rho family small GTPase TC10.
The Journal of biological chemistry 2005;280(5):3731-9.
2005: Lewis Hal A; Zhao Xun; Wang Chi; Sauder J Michael; Rooney Isabelle; Noland Brian W; Lorimer Don; Kearins Margaret C; Conners Kris; Condon Brad; Maloney Peter C; Guggino William B; Hunt John F; Emtage Spencer
Impact of the deltaF508 mutation in first nucleotide-binding domain of human cystic fibrosis transmembrane conductance regulator on domain folding and structure.
The Journal of biological chemistry 2005;280(2):1346-53.
2004: Hryciw Deanne H; Ekberg Jenny; Lee Aven; Lensink Ingrid L; Kumar Sharad; Guggino William B; Cook David I; Pollock Carol A; Poronnik Philip
Nedd4-2 functionally interacts with ClC-5: involvement in constitutive albumin endocytosis in proximal tubule cells.
The Journal of biological chemistry 2004;279(53):54996-5007.
2004: Kwon Sang-Ho; Guggino William B
Multiple sequences in the C terminus of MaxiK channels are involved in expression, movement to the cell surface, and apical localization.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(42):15237-42.
2004: Guggino William B; Banks-Schlegel Susan P
Macromolecular interactions and ion transport in cystic fibrosis.
American journal of respiratory and critical care medicine 2004;170(7):815-20.
2004: Sirninger Jeffrey; Muller Christian; Braag Sofia; Tang Qiushi; Yue Hungwen; Detrisac Carol; Ferkol Thomas; Guggino William B; Flotte Terence R
Functional characterization of a recombinant adeno-associated virus 5-pseudotyped cystic fibrosis transmembrane conductance regulator vector.
Human gene therapy 2004;15(9):832-41.
2004: Chikhlikar Priya; Barros de Arruda Luciana; Agrawal Shikha; Byrne Barry; Guggino William; August J Thomas; Marques Ernesto T A
Inverted terminal repeat sequences of adeno-associated virus enhance the antibody and CD8(+) responses to a HIV-1 p55Gag/LAMP DNA vaccine chimera.
Virology 2004;323(2):220-32.
2004: Karp Christopher L; Flick Leah M; Park Kiwon W; Softic Samir; Greer Todd M; Keledjian Raquel; Yang Rong; Uddin Jasim; Guggino William B; Atabani Sowsan F; Belkaid Yasmine; Xu Yan; Whitsett Jeffrey A; Accurso Frank J; Wills-Karp Marsha; Petasis Nicos A
Defective lipoxin-mediated anti-inflammatory activity in the cystic fibrosis airway.
Nature immunology 2004;5(4):388-92.
2004: Zeitlin Pamela L; Boyle Michael P; Guggino William B; Molina Luis
A phase I trial of intranasal Moli1901 for cystic fibrosis.
Chest 2004;125(1):143-9.
2004: Lewis Hal A; Buchanan Sean G; Burley Stephen K; Conners Kris; Dickey Mark; Dorwart Michael; Fowler Richard; Gao Xia; Guggino William B; Hendrickson Wayne A; Hunt John F; Kearins Margaret C; Lorimer Don; Maloney Peter C; Post Kai W; Rajashankar Kanagalaghatta R; Rutter Marc E; Sauder J Michael; Shriver Stephanie; Thibodeau Patrick H; Thomas Philip J; Zhang Marie; Zhao Xun; Emtage Spencer
Structure of nucleotide-binding domain 1 of the cystic fibrosis transmembrane conductance regulator.
The EMBO journal 2004;23(2):282-93.
2004: Wright Jerry M; Zeitlin Pamela L; Cebotaru Liudmila; Guggino Sandra E; Guggino William B
Gene expression profile analysis of 4-phenylbutyrate treatment of IB3-1 bronchial epithelial cell line demonstrates a major influence on heat-shock proteins.
Physiological genomics 2004;16(2):204-11.
2004: Cheng Jie; Wang Hua; Guggino William B
Modulation of mature cystic fibrosis transmembrane regulator protein by the PDZ domain protein CAL.
The Journal of biological chemistry 2004;279(3):1892-8.
2004: Guggino William B
The cystic fibrosis transmembrane regulator forms macromolecular complexes with PDZ domain scaffold proteins.
Proceedings of the American Thoracic Society 2004;1(1):28-32.
2003: Fischer Anne C; Beck Suzanne E; Smith Carolina I; Laube Beth L; Askin Frederic B; Guggino Sandra E; Adams Robert J; Flotte Terence R; Guggino William B
Successful transgene expression with serial doses of aerosolized rAAV2 vectors in rhesus macaques.
Molecular therapy : the journal of the American Society of Gene Therapy 2003;8(6):918-26.
2003: Hryciw Deanne H; Wang Yinghong; Devuyst Olivier; Pollock Carol A; Poronnik Philip; Guggino William B
Cofilin interacts with ClC-5 and regulates albumin uptake in proximal tubule cell lines.
The Journal of biological chemistry 2003;278(41):40169-76.
2003: Santos Ornellas D; Grozovsky R; Goldenberg R C; Carvalho D P; Fong P; Guggino W B; Morales M
Thyroid hormone modulates ClC-2 chloride channel gene expression in rat renal proximal tubules.
The Journal of endocrinology 2003;178(3):503-11.
2003: Nascimento Danielle S; Reis Carlos U; Goldenberg Regina C; Ortiga-Carvalho Tânia M; Pazos-Moura Carmen C; Guggino Sandra E; Guggino William B; Morales Marcelo M
Estrogen modulates ClC-2 chloride channel gene expression in rat kidney.
Pflügers Archiv : European journal of physiology 2003;446(5):593-9.
2003: Fong Peying; Argent Barry E; Guggino William B; Gray Michael A
Characterization of vectorial chloride transport pathways in the human pancreatic duct adenocarcinoma cell line HPAF.
American journal of physiology. Cell physiology 2003;285(2):C433-45.
2003: Flotte Terence R; Zeitlin Pamela L; Reynolds Thomas C; Heald Alison E; Pedersen Patty; Beck Suzanne; Conrad Carol K; Brass-Ernst Lois; Humphries Margaret; Sullivan Kevin; Wetzel Randall; Taylor George; Carter Barrie J; Guggino William B
Phase I trial of intranasal and endobronchial administration of a recombinant adeno-associated virus serotype 2 (rAAV2)-CFTR vector in adult cystic fibrosis patients: a two-part clinical study.
Human gene therapy 2003;14(11):1079-88.
2003: Christensen Erik I; Devuyst Olivier; Dom Geneviève; Nielsen Rikke; Van der Smissen Patrick; Verroust Pierre; Leruth Michèle; Guggino William B; Courtoy Pierre J
Loss of chloride channel ClC-5 impairs endocytosis by defective trafficking of megalin and cubilin in kidney proximal tubules.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(14):8472-7.
2003: Silva Ian V; Cebotaru Valeriu; Wang Hua; Wang Xi-Tao; Wang Sha Sha; Guo Gang; Devuyst Olivier; Thakker Rajesh V; Guggino William B; Guggino Sandra E
The ClC-5 knockout mouse model of Dent's disease has renal hypercalciuria and increased bone turnover.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2003;18(4):615-23.
2003: Boyle Michael P; Enke Raymond A; Mogayzel Peter J; Guggino William B; Martin Dana B; Agarwal Shikha; Zeitlin Pamela L
Effect of adeno-associated virus-specific immunoglobulin G in human amniotic fluid on gene transfer.
Human gene therapy 2003;14(4):365-73.
2003: Wang Shao-Xiong; Ikeda Masahiro; Guggino William B
The cytoplasmic tail of large conductance, voltage- and Ca2+-activated K+ (MaxiK) channel is necessary for its cell surface expression.
The Journal of biological chemistry 2003;278(4):2713-22.
2002: Devuyst Olivier; Guggino William B
Chloride channels in the kidney: lessons learned from knockout animals.
American journal of physiology. Renal physiology 2002;283(6):F1176-91.
2002: Beck Suzanne E; Laube Beth L; Barberena Carolina I; Fischer Anne C; Adams Robert J; Chesnut Kye; Flotte Terence R; Guggino William B
Deposition and expression of aerosolized rAAV vectors in the lungs of Rhesus macaques.
Molecular therapy : the journal of the American Society of Gene Therapy 2002;6(4):546-54.
2002: Ikeda Masahiro; Beitz Eric; Kozono David; Guggino William B; Agre Peter; Yasui Masato
Characterization of aquaporin-6 as a nitrate channel in mammalian cells. Requirement of pore-lining residue threonine 63.
The Journal of biological chemistry 2002;277(42):39873-9.
2002: Swiatecka-Urban Agnieszka; Duhaime Marc; Coutermarsh Bonita; Karlson Katherine H; Collawn James; Milewski Michal; Cutting Garry R; Guggino William B; Langford George; Stanton Bruce A
PDZ domain interaction controls the endocytic recycling of the cystic fibrosis transmembrane conductance regulator.
The Journal of biological chemistry 2002;277(42):40099-105.
2002: Lebeau Catherine; Hanaoka Kazushige; Moore-Hoon Marilyn L; Guggino William B; Beauwens Renaud; Devuyst Olivier
Basolateral chloride transporters in autosomal dominant polycystic kidney disease.
Pflügers Archiv : European journal of physiology 2002;444(6):722-31.
2002: Ikeda Masahiro; Guggino William B
Do polycystins function as cation channels?
Current opinion in nephrology and hypertension 2002;11(5):539-45.
2002: Hazama Akihiro; Kozono David; Guggino William B; Agre Peter; Yasui Masato
Ion permeation of AQP6 water channel protein. Single channel recordings after Hg2+ activation.
The Journal of biological chemistry 2002;277(32):29224-30.
2002: Wagner John A; Nepomuceno Ilynn B; Messner Anna H; Moran Mary Lynn; Batson Eric P; Dimiceli Sue; Brown Byron W; Desch Julie K; Norbash Alexander M; Conrad Carol K; Guggino William B; Flotte Terence R; Wine Jeffrey J; Carter Barrie J; Reynolds Thomas C; Moss Richard B; Gardner Phyllis
A phase II, double-blind, randomized, placebo-controlled clinical trial of tgAAVCF using maxillary sinus delivery in patients with cystic fibrosis with antrostomies.
Human gene therapy 2002;13(11):1349-59.
2002: Agre Peter; King Landon S; Yasui Masato; Guggino Wm B; Ottersen Ole Petter; Fujiyoshi Yoshinori; Engel Andreas; Nielsen Søren
Aquaporin water channels--from atomic structure to clinical medicine.
The Journal of physiology 2002;542(Pt 1):3-16.
2002: Ornellas Débora S; Nascimento Danielle S; Christoph Daniel H; Guggino William B; Morales Marcelo M
Aldosterone and high-NaCl diet modulate ClC-2 chloride channel gene expression in rat kidney.
Pflügers Archiv : European journal of physiology 2002;444(1-2):193-201.
2002: Schwiebert Erik M; Wallace Darren P; Braunstein Gavin M; King Sandi R; Peti-Peterdi Janos; Hanaoka Kazushige; Guggino William B; Guay-Woodford Lisa M; Bell P Darwin; Sullivan Lawrence P; Grantham Jared J; Taylor Amanda L
Autocrine extracellular purinergic signaling in epithelial cells derived from polycystic kidneys.
American journal of physiology. Renal physiology 2002;282(4):F763-75.
2002: Edmonds Rebecca D; Silva Ian V; Guggino William B; Butler Robert B; Zeitlin Pamela L; Blaisdell Carol J
ClC-5: ontogeny of an alternative chloride channel in respiratory epithelia.
American journal of physiology. Lung cellular and molecular physiology 2002;282(3):L501-7.
2002: Cheng Jie; Moyer Bryan D; Milewski Michal; Loffing Johannes; Ikeda Masahiro; Mickle John E; Cutting Garry R; Li Min; Stanton Bruce A; Guggino William B
A Golgi-associated PDZ domain protein modulates cystic fibrosis transmembrane regulator plasma membrane expression.
The Journal of biological chemistry 2002;277(5):3520-9.
2002: Ketchum Christian J; Yue Hongwen; Alessi Karen A; Devidas Shreenivas; Guggino William B; Maloney Peter C
Intracellular cysteines of the cystic fibrosis transmembrane conductance regulator (CFTR) modulate channel gating.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2002;12(1):1-8.
2001: Morales M M; Nascimento D S; Capella M A; Lopes A G; Guggino W B
Arginine vasopressin regulates CFTR and ClC-2 mRNA expression in rat kidney cortex and medulla.
Pflügers Archiv : European journal of physiology 2001;443(2):202-11.
2001: Boyle M P; Enke R A; Adams R J; Guggino W B; Zeitlin P L
In utero AAV-mediated gene transfer to rabbit pulmonary epithelium.
Molecular therapy : the journal of the American Society of Gene Therapy 2001;4(2):115-21.
2001: Guggino W B
Cystic fibrosis salt/fluid controversy: in the thick of it.
Nature medicine 2001;7(8):888-9.
2001: Milewski M I; Mickle J E; Forrest J K; Stafford D M; Moyer B D; Cheng J; Guggino W B; Stanton B A; Cutting G R
A PDZ-binding motif is essential but not sufficient to localize the C terminus of CFTR to the apical membrane.
Journal of cell science 2001;114(Pt 4):719-26.
2000: Hanaoka K; Qian F; Boletta A; Bhunia A K; Piontek K; Tsiokas L; Sukhatme V P; Guggino W B; Germino G G
Co-assembly of polycystin-1 and -2 produces unique cation-permeable currents.
Nature 2000;408(6815):990-4.
2000: Wang S S; Devuyst O; Courtoy P J; Wang X T; Wang H; Wang Y; Thakker R V; Guggino S; Guggino W B
Mice lacking renal chloride channel, CLC-5, are a model for Dent's disease, a nephrolithiasis disorder associated with defective receptor-mediated endocytosis.
Human molecular genetics 2000;9(20):2937-45.
2000: Boletta A; Qian F; Onuchic L F; Bhunia A K; Phakdeekitcharoen B; Hanaoka K; Guggino W; Monaco L; Germino G G
Polycystin-1, the gene product of PKD1, induces resistance to apoptosis and spontaneous tubulogenesis in MDCK cells.
Molecular cell 2000;6(5):1267-73.
2000: Hryciw D H; Guggino W B
Cystic fibrosis transmembrane conductance regulator and the outwardly rectifying chloride channel: a relationship between two chloride channels expressed in epithelial cells.
Clinical and experimental pharmacology & physiology 2000;27(11):892-5.
2000: Wang S; Yue H; Derin R B; Guggino W B; Li M
Accessory protein facilitated CFTR-CFTR interaction, a molecular mechanism to potentiate the chloride channel activity.
Cell 2000;103(1):169-79.
2000: Moyer B D; Duhaime M; Shaw C; Denton J; Reynolds D; Karlson K H; Pfeiffer J; Wang S; Mickle J E; Milewski M; Cutting G R; Guggino W B; Li M; Stanton B A
The PDZ-interacting domain of cystic fibrosis transmembrane conductance regulator is required for functional expression in the apical plasma membrane.
The Journal of biological chemistry 2000;275(35):27069-74.
2000: Guggino W B; Guggino S E
Amiloride-sensitive sodium channels contribute to the woes of the flu.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(18):9827-9.
2000: Hanaoka K; Guggino W B
cAMP regulates cell proliferation and cyst formation in autosomal polycystic kidney disease cells.
Journal of the American Society of Nephrology : JASN 2000;11(7):1179-87.
2000: Yue H; Devidas S; Guggino W B
The two halves of CFTR form a dual-pore ion channel.
The Journal of biological chemistry 2000;275(14):10030-4.
2000: Silva I V; Blaisdell C J; Guggino S E; Guggino W B
PTH regulates expression of ClC-5 chloride channel in the kidney.
American journal of physiology. Renal physiology 2000;278(2):F238-45.
2000: Morales M M; Capella M A; Sanches M V; Lopes A G; Guggino W B
Modulation of the mdr-1b gene in the kidney of rats subjected to dehydration or a high-salt diet.
Pflügers Archiv : European journal of physiology 2000;439(3):356-62.
1999: Hanaoka K; Wright J M; Cheglakov I B; Morita T; Guggino W B
A 59 amino acid insertion increases Ca(2+) sensitivity of rbslo1, a Ca2+ -activated K(+) channel in renal epithelia.
The Journal of membrane biology 1999;172(3):193-201.
1999: Yasui M; Hazama A; Kwon T H; Nielsen S; Guggino W B; Agre P
Rapid gating and anion permeability of an intracellular aquaporin.
Nature 1999;402(6758):184-7.
1999: Moyer B D; Denton J; Karlson K H; Reynolds D; Wang S; Mickle J E; Milewski M; Cutting G R; Guggino W B; Li M; Stanton B A
A PDZ-interacting domain in CFTR is an apical membrane polarization signal.
The Journal of clinical investigation 1999;104(10):1353-61.
1999: Beck S E; Jones L A; Chesnut K; Walsh S M; Reynolds T C; Carter B J; Askin F B; Flotte T R; Guggino W B
Repeated delivery of adeno-associated virus vectors to the rabbit airway.
Journal of virology 1999;73(11):9446-55.
1999: Schneider S W; Egan M E; Jena B P; Guggino W B; Oberleithner H; Geibel J P
Continuous detection of extracellular ATP on living cells by using atomic force microscopy.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(21):12180-5.
1999: Guggino W B
Cystic fibrosis and the salt controversy.
Cell 1999;96(5):607-10.
1999: Wagner J A; Messner A H; Moran M L; Daifuku R; Kouyama K; Desch J K; Manley S; Norbash A M; Conrad C K; Friborg S; Reynolds T; Guggino W B; Moss R B; Carter B J; Wine J J; Flotte T R; Gardner P
Safety and biological efficacy of an adeno-associated virus vector-cystic fibrosis transmembrane regulator (AAV-CFTR) in the cystic fibrosis maxillary sinus.
The Laryngoscope 1999;109(2 Pt 1):266-74.
1999: Schwiebert E M; Benos D J; Egan M E; Stutts M J; Guggino W B
CFTR is a conductance regulator as well as a chloride channel.
Physiological reviews 1999;79(1 Suppl):S145-66.
1999: Truong-Le V L; Walsh S M; Schweibert E; Mao H Q; Guggino W B; August J T; Leong K W
Gene transfer by DNA-gelatin nanospheres.
Archives of biochemistry and biophysics 1999;361(1):47-56.
1999: Afione S A; Wang J; Walsh S; Guggino W B; Flotte T R
Delayed expression of adeno-associated virus vector DNA.
Intervirology 1999;42(4):213-20.
1998: Taylor A L; Kudlow B A; Marrs K L; Gruenert D C; Guggino W B; Schwiebert E M
Bioluminescence detection of ATP release mechanisms in epithelia.
The American journal of physiology 1998;275(5 Pt 1):C1391-406.
1998: Jiang Q; Mak D; Devidas S; Schwiebert E M; Bragin A; Zhang Y; Skach W R; Guggino W B; Foskett J K; Engelhardt J F
Cystic fibrosis transmembrane conductance regulator-associated ATP release is controlled by a chloride sensor.
The Journal of cell biology 1998;143(3):645-57.
1998: Devidas S; Yue H; Guggino W B
The second half of the cystic fibrosis transmembrane conductance regulator forms a functional chloride channel.
The Journal of biological chemistry 1998;273(45):29373-80.
1998: Guggino W B
Focus on "exocytosis is not involved in activation of Cl- secretion via CFTR in Calu-3 airway epithelial cells".
The American journal of physiology 1998;275(4 Pt 1):C911-2.
1998: Tsukaguchi H; Shayakul C; Berger U V; Mackenzie B; Devidas S; Guggino W B; van Hoek A N; Hediger M A
Molecular characterization of a broad selectivity neutral solute channel.
The Journal of biological chemistry 1998;273(38):24737-43.
1998: Moyer B D; Loffing J; Schwiebert E M; Loffing-Cueni D; Halpin P A; Karlson K H; Ismailov I I; Guggino W B; Langford G M; Stanton B A
Membrane trafficking of the cystic fibrosis gene product, cystic fibrosis transmembrane conductance regulator, tagged with green fluorescent protein in madin-darby canine kidney cells.
The Journal of biological chemistry 1998;273(34):21759-68.
1998: Wang S; Raab R W; Schatz P J; Guggino W B; Li M
Peptide binding consensus of the NHE-RF-PDZ1 domain matches the C-terminal sequence of cystic fibrosis transmembrane conductance regulator (CFTR).
FEBS letters 1998;427(1):103-8.
1998: Wagner J A; Moran M L; Messner A H; Daifuku R; Conrad C K; Reynolds T; Guggino W B; Moss R B; Carter B J; Wine J J; Flotte T R; Gardner P
A phase I/II study of tgAAV-CF for the treatment of chronic sinusitis in patients with cystic fibrosis.
Human gene therapy 1998;9(6):889-909.
1998: Mickle J E; Macek M; Fulmer-Smentek S B; Egan M M; Schwiebert E; Guggino W; Moss R; Cutting G R
A mutation in the cystic fibrosis transmembrane conductance regulator gene associated with elevated sweat chloride concentrations in the absence of cystic fibrosis.
Human molecular genetics 1998;7(4):729-35.
1998: Schwiebert E M; Cid-Soto L P; Stafford D; Carter M; Blaisdell C J; Zeitlin P L; Guggino W B; Cutting G R
Analysis of ClC-2 channels as an alternative pathway for chloride conduction in cystic fibrosis airway cells.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(7):3879-84.
1998: Schwiebert E M; Morales M M; Devidas S; Egan M E; Guggino W B
Chloride channel and chloride conductance regulator domains of CFTR, the cystic fibrosis transmembrane conductance regulator.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(5):2674-9.
1998: Woo J S; Inoue C N; Hanaoka K; Schwiebert E M; Guggino S E; Guggino W B
Adenylyl cyclase is involved in desensitization and recovery of ATP-stimulated Cl- secretion in MDCK cells.
The American journal of physiology 1998;274(2 Pt 1):C371-8.
1998: Hackam A S; Wang T L; Guggino W B; Cutting G R
Sequences in the amino termini of GABA rho and GABA(A) subunits specify their selective interaction in vitro.
Journal of neurochemistry 1998;70(1):40-6.
1998: Schwiebert E M; Egan M E; Guggino W B
Assays of dynamics, mechanisms, and regulation of ATP transport and release: implications for study of ABC transporter function.
Methods in enzymology 1998;292():664-75.
1997: Inoue C N; Ko Y H; Guggino W B; Forster H G; Epstein M
Lysophosphatidic acid and platelet-derived growth factor synergistically stimulate growth of cultured rat mesangial cells.
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.) 1997;216(3):370-9.
1997: McNicholas C M; Nason M W; Guggino W B; Schwiebert E M; Hebert S C; Giebisch G; Egan M E
A functional CFTR-NBF1 is required for ROMK2-CFTR interaction.
The American journal of physiology 1997;273(5 Pt 2):F843-8.
1997: Devidas S; Guggino W B
CFTR: domains, structure, and function.
Journal of bioenergetics and biomembranes 1997;29(5):443-51.
1997: Morita T; Hanaoka K; Morales M M; Montrose-Rafizadeh C; Guggino W B
Cloning and characterization of maxi K+ channel alpha-subunit in rabbit kidney.
The American journal of physiology 1997;273(4 Pt 2):F615-24.
1997: Devidas S; Guggino W B
The cystic fibrosis transmembrane conductance regulator and ATP.
Current opinion in cell biology 1997;9(4):547-52.
1997: Oberleithner H; Geibel J; Guggino W; Henderson R M; Hunter M; Schneider S W; Schwab A; Wang W
Life on biomembranes viewed with the atomic force microscope.
Wiener klinische Wochenschrift 1997;109(12-13):419-23.
1997: Inoue C N; Woo J S; Schwiebert E M; Morita T; Hanaoka K; Guggino S E; Guggino W B
Role of purinergic receptors in chloride secretion in Caco-2 cells.
The American journal of physiology 1997;272(6 Pt 1):C1862-70.
1997: Xu X Z; Li H S; Guggino W B; Montell C
Coassembly of TRP and TRPL produces a distinct store-operated conductance.
Cell 1997;89(7):1155-64.
1997: Rubenstein R C; McVeigh U; Flotte T R; Guggino W B; Zeitlin P L
CFTR gene transduction in neonatal rabbits using an adeno-associated virus (AAV) vector.
Gene therapy 1997;4(5):384-92.
1997: Hackam A S; Wang T L; Guggino W B; Cutting G R
The N-terminal domain of human GABA receptor rho1 subunits contains signals for homooligomeric and heterooligomeric interaction.
The Journal of biological chemistry 1997;272(21):13750-7.
1997: Hackam A S; Wang T L; Guggino W B; Cutting G R
A 100 amino acid region in the GABA rho 1 subunit confers robust homo-oligomeric expression.
Neuroreport 1997;8(6):1425-30.
1997: Devuyst O; Golstein P E; Sanches M V; Piontek K; Wilson P D; Guggino W B; Dumont J E; Beauwens R
Expression of CFTR in human and bovine thyroid epithelium.
The American journal of physiology 1997;272(4 Pt 1):C1299-308.
1997: Schwiebert E M; Potter E D; Hwang T H; Woo J S; Ding C; Qiu W; Guggino W B; Levine M A; Guggino S E
cGMP stimulates sodium and chloride currents in rat tracheal airway epithelia.
The American journal of physiology 1997;272(3 Pt 1):C911-22.
1997: Agre P; Lee M D; Devidas S; Guggino W B
Aquaporins and ion conductance.
Science (New York, N.Y.) 1997;275(5305):1490; author reply 1492.
1997: Mogayzel P J; Henning K A; Bittner M L; Novotny E A; Schwiebert E M; Guggino W B; Jiang Y; Rosenfeld M A
Functional human CFTR produced by stable Chinese hamster ovary cell lines derived using yeast artificial chromosomes.
Human molecular genetics 1997;6(1):59-68.
1996: Devuyst O; Burrow C R; Schwiebert E M; Guggino W B; Wilson P D
Developmental regulation of CFTR expression during human nephrogenesis.
The American journal of physiology 1996;271(3 Pt 2):F723-35.
1996: Conrad C K; Allen S S; Afione S A; Reynolds T C; Beck S E; Fee-Maki M; Barrazza-Ortiz X; Adams R; Askin F B; Carter B J; Guggino W B; Flotte T R
Safety of single-dose administration of an adeno-associated virus (AAV)-CFTR vector in the primate lung.
Gene therapy 1996;3(8):658-68.
1996: McNicholas C M; Guggino W B; Schwiebert E M; Hebert S C; Giebisch G; Egan M E
Sensitivity of a renal K+ channel (ROMK2) to the inhibitory sulfonylurea compound glibenclamide is enhanced by coexpression with the ATP-binding cassette transporter cystic fibrosis transmembrane regulator.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(15):8083-8.
1996: Flotte T; Carter B; Conrad C; Guggino W; Reynolds T; Rosenstein B; Taylor G; Walden S; Wetzel R
A phase I study of an adeno-associated virus-CFTR gene vector in adult CF patients with mild lung disease.
Human gene therapy 1996;7(9):1145-59.
1996: Morales M M; Carroll T P; Morita T; Schwiebert E M; Devuyst O; Wilson P D; Lopes A G; Stanton B A; Dietz H C; Cutting G R; Guggino W B
Both the wild type and a functional isoform of CFTR are expressed in kidney.
The American journal of physiology 1996;270(6 Pt 2):F1038-48.
1996: Hwang T H; Schwiebert E M; Guggino W B
Apical and basolateral ATP stimulates tracheal epithelial chloride secretion via multiple purinergic receptors.
The American journal of physiology 1996;270(6 Pt 1):C1611-23.
1996: Afione S A; Conrad C K; Kearns W G; Chunduru S; Adams R; Reynolds T C; Guggino W B; Cutting G R; Carter B J; Flotte T R
In vivo model of adeno-associated virus vector persistence and rescue.
Journal of virology 1996;70(5):3235-41.
1996: Hanaoka K; Devuyst O; Schwiebert E M; Wilson P D; Guggino W B
A role for CFTR in human autosomal dominant polycystic kidney disease.
The American journal of physiology 1996;270(1 Pt 1):C389-99.
1995: Wang T L; Hackam A S; Guggino W B; Cutting G R
A single amino acid in gamma-aminobutyric acid rho 1 receptors affects competitive and noncompetitive components of picrotoxin inhibition.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(25):11751-5.
1995: Calamita G; Bishai W R; Preston G M; Guggino W B; Agre P
Molecular cloning and characterization of AqpZ, a water channel from Escherichia coli.
The Journal of biological chemistry 1995;270(49):29063-6.
1995: Zeitlin P L; Chu S; Conrad C; McVeigh U; Ferguson K; Flotte T R; Guggino W B
Alveolar stem cell transduction by an adeno-associated viral vector.
Gene therapy 1995;2(9):623-31.
1995: Wang T L; Hackam A; Guggino W B; Cutting G R
A single histidine residue is essential for zinc inhibition of GABA rho 1 receptors.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1995;15(11):7684-91.
1995: Vandorpe D; Kizer N; Ciampollilo F; Moyer B; Karlson K; Guggino W B; Stanton B A
CFTR mediates electrogenic chloride secretion in mouse inner medullary collecting duct (mIMCD-K2) cells.
The American journal of physiology 1995;269(3 Pt 1):C683-9.
1995: Schwiebert E M; Gruenert D C; Guggino W B; Stanton B A
G protein G alpha i-2 inhibits outwardly rectifying chloride channels in human airway epithelial cells.
The American journal of physiology 1995;269(2 Pt 1):C451-6.
1995: Bredt D S; Wang T L; Cohen N A; Guggino W B; Snyder S H
Cloning and expression of two brain-specific inwardly rectifying potassium channels.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(15):6753-7.
1995: Fulmer S B; Schwiebert E M; Morales M M; Guggino W B; Cutting G R
Two cystic fibrosis transmembrane conductance regulator mutations have different effects on both pulmonary phenotype and regulation of outwardly rectified chloride currents.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(15):6832-6.
1995: Guay-Broder C; Jacobson K A; Barnoy S; Cabantchik Z I; Guggino W B; Zeitlin P L; Turner R J; Vergara L; Eidelman O; Pollard H B
A1 receptor antagonist 8-cyclopentyl-1,3-dipropylxanthine selectively activates chloride efflux from human epithelial and mouse fibroblast cell lines expressing the cystic fibrosis transmembrane regulator delta F508 mutation.
Biochemistry 1995;34(28):9079-87.
1995: Murray C B; Morales M M; Flotte T R; McGrath-Morrow S A; Guggino W B; Zeitlin P L
CIC-2: a developmentally dependent chloride channel expressed in the fetal lung and downregulated after birth.
American journal of respiratory cell and molecular biology 1995;12(6):597-604.
1995: Li X J; Xu R H; Guggino W B; Snyder S H
Alternatively spliced forms of the alpha subunit of the epithelial sodium channel: distinct sites for amiloride binding and channel pore.
Molecular pharmacology 1995;47(6):1133-40.
1995: Schwiebert E M; Egan M E; Hwang T H; Fulmer S B; Allen S S; Cutting G R; Guggino W B
CFTR regulates outwardly rectifying chloride channels through an autocrine mechanism involving ATP.
Cell 1995;81(7):1063-73.
1995: Carroll T P; Morales M M; Fulmer S B; Allen S S; Flotte T R; Cutting G R; Guggino W B
Alternate translation initiation codons can create functional forms of cystic fibrosis transmembrane conductance regulator.
The Journal of biological chemistry 1995;270(20):11941-6.
1995: Mulders S M; Preston G M; Deen P M; Guggino W B; van Os C H; Agre P
Water channel properties of major intrinsic protein of lens.
The Journal of biological chemistry 1995;270(15):9010-16.
1995: Cid L P; Montrose-Rafizadeh C; Smith D I; Guggino W B; Cutting G R
Cloning of a putative human voltage-gated chloride channel (CIC-2) cDNA widely expressed in human tissues.
Human molecular genetics 1995;4(3):407-13.
1995: Flotte T R; Barraza-Ortiz X; Solow R; Afione S A; Carter B J; Guggino W B
An improved system for packaging recombinant adeno-associated virus vectors capable of in vivo transduction.
Gene therapy 1995;2(1):29-37.
1995: Egan M E; Schwiebert E M; Guggino W B
Differential expression of ORCC and CFTR induced by low temperature in CF airway epithelial cells.
The American journal of physiology 1995;268(1 Pt 1):C243-51.
1995: Raina S; Preston G M; Guggino W B; Agre P
Molecular cloning and characterization of an aquaporin cDNA from salivary, lacrimal, and respiratory tissues.
The Journal of biological chemistry 1995;270(4):1908-12.
1994: Jung J S; Bhat R V; Preston G M; Guggino W B; Baraban J M; Agre P
Molecular characterization of an aquaporin cDNA from brain: candidate osmoreceptor and regulator of water balance.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(26):13052-6.
1994: Wang T L; Guggino W B; Cutting G R
A novel gamma-aminobutyric acid receptor subunit (rho 2) cloned from human retina forms bicuculline-insensitive homooligomeric receptors in Xenopus oocytes.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1994;14(11 Pt 1):6524-31.
1994: Schwiebert E M; Flotte T; Cutting G R; Guggino W B
Both CFTR and outwardly rectifying chloride channels contribute to cAMP-stimulated whole cell chloride currents.
The American journal of physiology 1994;266(5 Pt 1):C1464-77.
1994: Jung J S; Preston G M; Smith B L; Guggino W B; Agre P
Molecular structure of the water channel through aquaporin CHIP. The hourglass model.
The Journal of biological chemistry 1994;269(20):14648-54.
1994: Rao M C; Bissonnette G B; Mahaffey T; Guggino W B; Goldstein J L
Rectal epithelial expression of protein kinase A phosphorylation of cystic fibrosis transmembrane conductance regulator.
Gastroenterology 1994;106(4):890-8.
1994: Preston G M; Jung J S; Guggino W B; Agre P
Membrane topology of aquaporin CHIP. Analysis of functional epitope-scanning mutants by vectorial proteolysis.
The Journal of biological chemistry 1994;269(3):1668-73.
1993: Flotte T R; Afione S A; Conrad C; McGrath S A; Solow R; Oka H; Zeitlin P L; Guggino W B; Carter B J
Stable in vivo expression of the cystic fibrosis transmembrane conductance regulator with an adeno-associated virus vector.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(22):10613-7.
1993: Agre P; Preston G M; Smith B L; Jung J S; Raina S; Moon C; Guggino W B; Nielsen S
Aquaporin CHIP: the archetypal molecular water channel.
The American journal of physiology 1993;265(4 Pt 2):F463-76.
1993: Lu L; Markakis D; Guggino W B
Identification and regulation of whole-cell Cl- and Ca(2+)-activated K+ currents in cultured medullary thick ascending limb cells.
The Journal of membrane biology 1993;135(2):181-9.
1993: Lu L; Yang T; Markakis D; Guggino W B; Craig R W
Alterations in a voltage-gated K+ current during the differentiation of ML-1 human myeloblastic leukemia cells.
The Journal of membrane biology 1993;132(3):267-74.
1993: Kusama T; Wang T L; Guggino W B; Cutting G R; Uhl G R
GABA rho 2 receptor pharmacological profile: GABA recognition site similarities to rho 1.
European journal of pharmacology 1993;245(1):83-4.
1993: Guggino W B
Outwardly rectifying chloride channels and CF: a divorce and remarriage.
Journal of bioenergetics and biomembranes 1993;25(1):27-35.
1993: Flotte T R; Afione S A; Solow R; Drumm M L; Markakis D; Guggino W B; Zeitlin P L; Carter B J
Expression of the cystic fibrosis transmembrane conductance regulator from a novel adeno-associated virus promoter.
The Journal of biological chemistry 1993;268(5):3781-90.
1993: Preston G M; Jung J S; Guggino W B; Agre P
The mercury-sensitive residue at cysteine 189 in the CHIP28 water channel.
The Journal of biological chemistry 1993;268(1):17-20.
1992: Egan M E; Wagner M H; Zeitlin P L; Guggino W B
Modulation of ion transport in cultured rabbit tracheal epithelium by lipoxygenase metabolites.
American journal of respiratory cell and molecular biology 1992;7(5):500-6.
1992: Montrose-Rafizadeh C; Blackmon D L; Hamosh A; Oliva M M; Hawkins A L; Curristin S M; Griffin C A; Yang V W; Guggino W B; Cutting G R
Regulation of cystic fibrosis transmembrane conductance regulator (CFTR) gene transcription and alternative RNA splicing in a model of developing intestinal epithelium.
The Journal of biological chemistry 1992;267(27):19299-305.
1992: Egan M; Flotte T; Afione S; Solow R; Zeitlin P L; Carter B J; Guggino W B
Defective regulation of outwardly rectifying Cl- channels by protein kinase A corrected by insertion of CFTR.
Nature 1992;358(6387):581-4.
1992: Preston G M; Carroll T P; Guggino W B; Agre P
Appearance of water channels in Xenopus oocytes expressing red cell CHIP28 protein.
Science (New York, N.Y.) 1992;256(5055):385-7.
1992: Bargon J; Trapnell B C; Chu C S; Rosenthal E R; Yoshimura K; Guggino W B; Dalemans W; Pavirani A; Lecocq J P; Crystal R G
Down-regulation of cystic fibrosis transmembrane conductance regulator gene expression by agents that modulate intracellular divalent cations.
Molecular and cellular biology 1992;12(4):1872-8.
1992: Wiebke J L; Montrose-Rafizadeh C; Zeitlin P L; Guggino W B
Effect of hypoxia on endothelin-1 production by pulmonary vascular endothelial cells.
Biochimica et biophysica acta 1992;1134(2):105-11.
1991: Crawford I; Maloney P C; Zeitlin P L; Guggino W B; Hyde S C; Turley H; Gatter K C; Harris A; Higgins C F
Immunocytochemical localization of the cystic fibrosis gene product CFTR.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(20):9262-6.
1991: Trapnell B C; Zeitlin P L; Chu C S; Yoshimura K; Nakamura H; Guggino W B; Bargon J; Banks T C; Dalemans W; Pavirani A
Down-regulation of cystic fibrosis gene mRNA transcript levels and induction of the cystic fibrosis chloride secretory phenotype in epithelial cells by phorbol ester.
The Journal of biological chemistry 1991;266(16):10319-23.
1991: Zeitlin P L; Lu L; Rhim J; Cutting G; Stetten G; Kieffer K A; Craig R; Guggino W B
A cystic fibrosis bronchial epithelial cell line: immortalization by adeno-12-SV40 infection.
American journal of respiratory cell and molecular biology 1991;4(4):313-9.
1991: Cutting G R; Lu L; O'Hara B F; Kasch L M; Montrose-Rafizadeh C; Donovan D M; Shimada S; Antonarakis S E; Guggino W B; Uhl G R
Cloning of the gamma-aminobutyric acid (GABA) rho 1 cDNA: a GABA receptor subunit highly expressed in the retina.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(7):2673-7.
1991: Montrose-Rafizadeh C; Guggino W B
Role of intracellular calcium in volume regulation by rabbit medullary thick ascending limb cells.
The American journal of physiology 1991;260(3 Pt 2):F402-9.
1991: Montrose-Rafizadeh C; Guggino W B; Montrose M H
Cellular differentiation regulates expression of Cl- transport and cystic fibrosis transmembrane conductance regulator mRNA in human intestinal cells.
The Journal of biological chemistry 1991;266(7):4495-9.
1991: Hwang T C; Guggino W B
Regulation of epithelial chloride channels: roles of protein kinases and arachidonic acid.
Advances in experimental medicine and biology 1991;290():209-23; discussion 223-4.
1990: Lu L; Montrose-Rafizadeh M; Guggino W B
Ca2(+)-activated K+ channels from rabbit kidney medullary thick ascending limb cells expressed in Xenopus oocytes.
The Journal of biological chemistry 1990;265(27):16190-4.
1990: Hwang T C; Guggino S E; Guggino W B
Direct modulation of secretory chloride channels by arachidonic and other cis unsaturated fatty acids.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(15):5706-9.
1990: Lu L; Montrose-Rafizadeh C; Hwang T C; Guggino W B
A delayed rectifier potassium current in Xenopus oocytes.
Biophysical journal 1990;57(6):1117-23.
1990: Montrose-Rafizadeh C; Guggino W B
Cell volume regulation in the nephron.
Annual review of physiology 1990;52():761-72.
1990: Guggino W B; Markakis D; Amzel L M
Measurements of volume and shape changes in isolated tubules.
Methods in enzymology 1990;191():371-9.
1989: Lu L; Zeitlin P L; Guggino W B; Craig R W
Gene transfer by lipofection in rabbit and human secretory epithelial cells.
Pflügers Archiv : European journal of physiology 1989;415(2):198-203.
1989: Taniguchi J; Guggino W B
Membrane stretch: a physiological stimulator of Ca2+-activated K+ channels in thick ascending limb.
The American journal of physiology 1989;257(3 Pt 2):F347-52.
1989: Guggino W B; Guggino S E
Renal anion transport.
Kidney international 1989;36(3):385-91.
1989: Cornejo M; Guggino S E; Guggino W B
Ca2+-activated K+ channels from cultured renal medullary thick ascending limb cells: effects of pH.
The Journal of membrane biology 1989;110(1):49-55.
1989: Hilden S A; Johns C A; Guggino W B; Madias N E
Techniques for isolation of brush-border and basolateral membrane vesicles from dog kidney cortex.
Biochimica et biophysica acta 1989;983(1):77-81.
1989: Hwang T C; Lu L; Zeitlin P L; Gruenert D C; Huganir R; Guggino W B
Cl- channels in CF: lack of activation by protein kinase C and cAMP-dependent protein kinase.
Science (New York, N.Y.) 1989;244(4910):1351-3.
1989: Zeitlin P L; Wagner M; Markakis D; Loughlin G M; Guggino W B
Steroid hormones: modulators of Na+ absorption and Cl- secretion in cultured tracheal epithelia.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(7):2502-5.
1989: Cornejo M; Guggino S E; Sastre A; Guggino W B
Isomeric yohimbine alkaloids block calcium-activated K+ channels in medullary thick ascending limb cells of rabbit kidney.
The Journal of membrane biology 1989;107(1):25-33.
1988: Guggino W B; Oberleithner H; Giebisch G
The amphibian diluting segment.
The American journal of physiology 1988;254(5 Pt 2):F615-27.
1988: Zeitlin P L; Loughlin G M; Guggino W B
Ion transport in cultured fetal and adult rabbit tracheal epithelia.
The American journal of physiology 1988;254(5 Pt 1):C691-8.
1988: Lopes A G; Amzel L M; Markakis D; Guggino W B
Cell volume regulation by the thin descending limb of Henle's loop.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(8):2873-7.
1987: Guggino S E; Guggino W B; Green N; Sacktor B
Blocking agents of Ca2+-activated K+ channels in cultured medullary thick ascending limb cells.
The American journal of physiology 1987;252(2 Pt 1):C128-37.
1987: Guggino S E; Guggino W B; Green N; Sacktor B
Ca2+-activated K+ channels in cultured medullary thick ascending limb cells.
The American journal of physiology 1987;252(2 Pt 1):C121-7.
1987: Lopes A G; Guggino W B
Volume regulation in the early proximal tubule of the Necturus kidney.
The Journal of membrane biology 1987;97(2):117-25.
1987: Cornejo M; Guggino S E; Guggino W B
Modification of Ca2+-activated K+ channels in cultured medullary thick ascending limb cells by N-bromoacetamide.
The Journal of membrane biology 1987;99(2):147-55.
1986: Guggino W B
Functional heterogeneity in the early distal tubule of the Amphiuma kidney: evidence for two modes of Cl- and K+ transport across the basolateral cell membrane.
The American journal of physiology 1986;250(3 Pt 2):F430-40.
1985: Guggino S E; Suarez-Isla B A; Guggino W B; Sacktor B
Forskolin and antidiuretic hormone stimulate a Ca2+-activated K+ channel in cultured kidney cells.
The American journal of physiology 1985;249(3 Pt 2):F448-55.
1985: Guggino W B; Oberleithner H; Giebisch G
Relationship between cell volume and ion transport in the early distal tubule of the Amphiuma kidney.
The Journal of general physiology 1985;86(1):31-58.
1985: Oberleithner H; Guggino W; Giebisch G
Resistance properties of the diluting segment of Amphiuma kidney: influence of potassium adaptation.
The Journal of membrane biology 1985;88(2):139-47.
1984: Reuss L; Lewis S A; Wills N K; Helman S I; Cox T C; Boron W F; Siebens A W; Guggino W B; Giebisch G; Schultz S G
Ion transport processes in basolateral membranes of epithelia.
Federation proceedings 1984;43(10):2488-502.
1984: Matsumura Y; Cohen B; Guggino W B; Giebisch G
Electrical effects of potassium and bicarbonate on proximal tubule cells of Necturus.
The Journal of membrane biology 1984;79(2):145-52.
1984: Matsumura Y; Cohen B; Guggino W B; Giebisch G
Regulation of the basolateral potassium conductance of the Necturus proximal tubule.
The Journal of membrane biology 1984;79(2):153-61.
1983: Oberleithner H; Ritter M; Lang F; Guggino W
Anthracene-9-carboxylic acid inhibits renal chloride reabsorption.
Pflügers Archiv : European journal of physiology 1983;398(2):172-4.
1983: Oberleithner H; Guggino W; Giebisch G
Potassium transport in the early distal tubule of Amphiuma kidney. Effects of potassium adaptation.
Pflügers Archiv : European journal of physiology 1983;396(3):185-91.
1983: Oberleithner H; Guggino W; Giebisch G
The effect of furosemide on luminal sodium, chloride and potassium transport in the early distal tubule of Amphiuma kidney. Effects of potassium adaptation.
Pflügers Archiv : European journal of physiology 1983;396(1):27-33.
1983: London R; Cohen B; Guggino W B; Giebisch G
Regulation of intracellular chloride activity during perfusion with hypertonic solutions in the Necturus proximal tubule.
The Journal of membrane biology 1983;75(3):253-8.
1983: Guggino W B; London R; Boulpaep E L; Giebisch G
Chloride transport across the basolateral cell membrane of the Necturus proximal tubule: dependence on bicarbonate and sodium.
The Journal of membrane biology 1983;71(3):227-40.
1982: Oberleithner H; Guggino W; Giebisch G
Mechanism of distal tubular chloride transport in Amphiuma kidney.
The American journal of physiology 1982;242(4):F331-9.
1982: Guggino W B; Windhager E E; Boulpaep E L; Giebisch G
Cellular and paracellular resistances of the Necturus proximal tubule.
The Journal of membrane biology 1982;67(2):143-54.
1982: Guggino W B; Boulpaep E L; Giebisch G
Electrical properties of chloride transport across the necturus proximal tubule.
The Journal of membrane biology 1982;65(3):185-96.
1981: Giebisch G; Cemerikic D; Oberleithner H; Guggino W; Biagi B
Ion activity measurements in single renal tubules.
Society of General Physiologists series 1981;36():163-79.
1980: Guggino W B
Salt balance in embryos of Fundulus heteroclitus and F. bermudae adapted to seawater.
The American journal of physiology 1980;238(1):R42-9.
1980: Guggino W B
Water balance in embryos of Fundulus heteroclitus and F. bermudae in seawater.
The American journal of physiology 1980;238(1):R36-41.

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