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Alessandro Guidotti

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Francesco Matrisciano; Ferdinando Nicoletti; Patricia Tueting; Bashkim Kadriu; Ishani Dalal; John M Davis; Dennis Grayson; Alessandro Guidotti
Epigenetic modifications of GABAergic interneurons are associated with the schizophrenia-like phenotype induced by prenatal stress in mice.
Alessandro Guidotti; Subhash C Pandey; Marin Veldic; Weihan Zhao; Dulal K Bhaumik; Erbo Dong; David P Gavin; Dennis R Grayson
DNA methylation/demethylation network expression in psychotic patients with a history of alcohol abuse.
Dennis R Grayson; Alessandro Guidotti
The dynamics of DNA methylation in schizophrenia and related psychiatric disorders.

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2013: Francesco Matrisciano; Ferdinando Nicoletti; Patricia Tueting; Bashkim Kadriu; Ishani Dalal; John M Davis; Dennis Grayson; Alessandro Guidotti
Epigenetic modifications of GABAergic interneurons are associated with the schizophrenia-like phenotype induced by prenatal stress in mice.
Neuropharmacology 2013;68():184-94.
2013: Alessandro Guidotti; Subhash C Pandey; Marin Veldic; Weihan Zhao; Dulal K Bhaumik; Erbo Dong; David P Gavin; Dennis R Grayson
DNA methylation/demethylation network expression in psychotic patients with a history of alcohol abuse.
Alcoholism, clinical and experimental research 2013;37(3):417-24.
2013: Dennis R Grayson; Alessandro Guidotti
The dynamics of DNA methylation in schizophrenia and related psychiatric disorders.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2013;38(1):138-66.
2012: Bashkim Kadriu; Alessandro Guidotti; Ying Chen; Dennis Grayson
DNA methyltransferases1 (DNMT1) and 3a (DNMT3a) colocalize with GAD67-positive neurons in the GAD67-GFP mouse brain.
The Journal of comparative neurology 2012;520(9):1951-64.
2012: Francesco Matrisciano; Ferdinando Nicoletti; Patricia Tueting; Stefania Maccari; Alessandro Guidotti
Pharmacological activation of group-II metabotropic glutamate receptors corrects a schizophrenia-like phenotype induced by prenatal stress in mice.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2012;37(4):929-38.
2012: Pietro Paolo Sanna; Vez Repunte-Canonigo; Alessandro Guidotti
Gene profiling of laser-microdissected brain regions and individual cells in drug abuse and schizophrenia research.
Methods in molecular biology (Clifton, N.J.) 2012;829():541-50.
2012: David Peter Gavin; Erbo Dong; Rajiv P Sharma; Kayla A Chase; Francesco Matrisciano; Alessandro Guidotti
Growth arrest and DNA-damage-inducible, beta (GADD45b)-mediated DNA demethylation in major psychosis.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2012;37(2):531-42.
2011: Bashkim Kadriu; John Larson; Madhusoodana P Nambiar; John M Davis; James Gocel; Alessandro Guidotti; James Auta
Absence of tolerance to the anticonvulsant and neuroprotective effects of imidazenil against DFP-induced seizure and neuronal damage.
Neuropharmacology 2011;61(8):1463-9.
2011: Stephen R Marder; Bita Moghaddam; Eric J Nestler; Bryan Roth; Akira Saw; Edward M Scolnick; Patrick F Sullivan; Daniel R Welnberger; Akira Sawa; Schahram Akbarian; John A Allen; Robert W Buchanan; Brian Campbell; Marc G Caron; P Jeffrey Conn; Susan R George; Mark A Geyer; Jay A Gingrich; Alessandro Guidotti; Stephen J Haggarty; Maria Karayiorgou; John H Krystal; Amanda J Law; Jeffrey A Lieberman; Michelle Solis
Advancing drug discovery for schizophrenia.
Annals of the New York Academy of Sciences 2011;1236():30-43.
2011: Norton Neff; Italo Mocchetti; Alessandro Guidotti
Preface. Fifty years of Neuropharmacology a tribute to Ermino Costa.
Pharmacological research : the official journal of the Italian Pharmacological Society 2011;64(4):309.
2011: Alessandro Guidotti; Dennis Grayson
A neurochemical basis for an epigenetic vision of psychiatric disorders (1994-2009).
Pharmacological research : the official journal of the Italian Pharmacological Society 2011;64(4):344-9.
2011: Italo Mocchetti; Alessandro Guidotti
The Fidia-Georgetown Institute for the Neurosciences (FGIN) 1985-1994.
Pharmacological research : the official journal of the Italian Pharmacological Society 2011;64(4):314-5.
2011: Francesco Matrisciano; Ferdinando Nicoletti; Erbo Dong; David Peter Gavin; Alessandro Guidotti
Activation of group II metabotropic glutamate receptors promotes DNA demethylation in the mouse brain.
Molecular pharmacology 2011;80(1):174-82.
2011: Ekrem Maloku; Bashkim Kadriu; Adrian Zhubi; Erbo Dong; Fabio Pibiri; Rosalba Satta; Alessandro Guidotti
Selective α4β2 nicotinic acetylcholine receptor agonists target epigenetic mechanisms in cortical GABAergic neurons.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2011;36(7):1366-74.
2011: Alessandro Guidotti; James Auta; Ying Chen; John M Davis; Erbo Dong; David Peter Gavin; Dennis Grayson; Francesco Matrisciano; Graziano Pinna; R Satta; Rajiv P Sharma; Lucio Tremolizzo; Patricia Tueting
Epigenetic GABAergic targets in schizophrenia and bipolar disorder.
Neuropharmacology 2011;60(7-8):1007-16.
2011: Bashkim Kadriu; Alessandro Guidotti; Erminio Costa; John M Davis; James Auta
Acute imidazenil treatment after the onset of DFP-induced seizure is more effective and longer lasting than midazolam at preventing seizure activity and brain neuropathology.
Toxicological sciences : an official journal of the Society of Toxicology 2011;120(1):136-45.
2010: Erbo Dong; Ying Chen; David Peter Gavin; Dennis Grayson; Alessandro Guidotti
Valproate induces DNA demethylation in nuclear extracts from adult mouse brain.
Epigenetics : official journal of the DNA Methylation Society 2010;5(8):730-5.
2010: Patricia Tueting; John M Davis; Marin Veldic; Fabio Pibiri; Bashkim Kadriu; Alessandro Guidotti; Erminio Costa
L-methionine decreases dendritic spine density in mouse frontal cortex.
Neuroreport 2010;21(8):543-8.
2010: Robert C Smith; Adrian Zhubi; Ekrem Maloku; Henry Sershen; Abel Lajtha; John M Davis; Erminio Costa; Alessandro Guidotti
Varenicline treatment decreases DNMT1 mRNA expression in lymphocytes of schizophrenic patients who are cigarette smokers.
Schizophrenia research 2010;119(1-3):269-70.
2010: James Auta; Bashkim Kadriu; Pietro Giusti; Erminio Costa; Alessandro Guidotti
Anticonvulsant, anxiolytic, and non-sedating actions of imidazenil and other imidazo-benzodiazepine carboxamide derivatives.
Pharmacology, biochemistry, and behavior 2010;95(4):383-9.
2010: Ekrem Maloku; Ignacio R Covelo; Ingeborg Hanbauer; Alessandro Guidotti; Bashkim Kadriu; Qiaoyan Hu; John M Davis; Erminio Costa
Lower number of cerebellar Purkinje neurons in psychosis is associated with reduced reelin expression.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(9):4407-11.
2009: Erbo Dong; Dennis Grayson; Alessandro Guidotti; Erminio Costa
Antipsychotic subtypes can be characterized by differences in their ability to modify GABAergic promoter methylation.
Epigenomics 2009;1(1):201-11.
2009: Adrian Zhubi; Marin Veldic; N V Puri; Bashkim Kadriu; Héctor J Caruncho; I Loza; H Sershen; A Lajtha; R C Smith; Alessandro Guidotti; John M Davis; Erminio Costa
An upregulation of DNA-methyltransferase 1 and 3a expressed in telencephalic GABAergic neurons of schizophrenia patients is also detected in peripheral blood lymphocytes.
Schizophrenia research 2009;111(1-3):115-22.
2009: Dennis Grayson; Ying Chen; Erbo Dong; Marija Kundakovic; Alessandro Guidotti
From trans-methylation to cytosine methylation: evolution of the methylation hypothesis of schizophrenia.
Epigenetics : official journal of the DNA Methylation Society 2009;4(3):144-9.
2009: Bashkim Kadriu; Alessandro Guidotti; Erminio Costa; James Auta
Imidazenil, a non-sedating anticonvulsant benzodiazepine, is more potent than diazepam in protecting against DFP-induced seizures and neuronal damage.
Toxicology 2009;256(3):164-74.
2009: Graziano Pinna; Erminio Costa; Alessandro Guidotti
SSRIs act as selective brain steroidogenic stimulants (SBSSs) at low doses that are inactive on 5-HT reuptake.
Current opinion in pharmacology 2009;9(1):24-30.
2009: Alessandro Guidotti; Erbo Dong; Marija Kundakovic; Rosalba Satta; Dennis Grayson; Erminio Costa
Characterization of the action of antipsychotic subtypes on valproate-induced chromatin remodeling.
Trends in pharmacological sciences 2009;30(2):55-60.
2009: Marija Kundakovic; Ying Chen; Alessandro Guidotti; Dennis Grayson
The reelin and GAD67 promoters are activated by epigenetic drugs that facilitate the disruption of local repressor complexes.
Molecular pharmacology 2009;75(2):342-54.
2009: Erminio Costa; Ying Chen; Erbo Dong; Dennis Grayson; Marija Kundakovic; Ekrem Maloku; William Ruzicka; Rosalba Satta; Marin Veldic; Adrian Zhubi; Alessandro Guidotti
GABAergic promoter hypermethylation as a model to study the neurochemistry of schizophrenia vulnerability.
Expert review of neurotherapeutics 2009;9(1):87-98.
2008: R Satta; Ekrem Maloku; Adrian Zhubi; Fabio Pibiri; M Hajos; Erminio Costa; Alessandro Guidotti
Nicotine decreases DNA methyltransferase 1 expression and glutamic acid decarboxylase 67 promoter methylation in GABAergic interneurons.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(42):16356-61.
2008: Graziano Pinna; Roberto Carlos Agis-Balboa; Fabio Pibiri; Marianela Nelson; Alessandro Guidotti; Erminio Costa
Neurosteroid biosynthesis regulates sexually dimorphic fear and aggressive behavior in mice.
Neurochemical research 2008;33(10):1990-2007.
2008: Fabio Pibiri; Alan P Kozikowski; Graziano Pinna; James Auta; Bashkim Kadriu; Erminio Costa; Alessandro Guidotti
The combination of huperzine A and imidazenil is an effective strategy to prevent diisopropyl fluorophosphate toxicity in mice.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(37):14169-74.
2008: Erbo Dong; M Nelson; Dennis Grayson; Erminio Costa; Alessandro Guidotti
Clozapine and sulpiride but not haloperidol or olanzapine activate brain DNA demethylation.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(36):13614-9.
2008: James Auta; Francesco Impagnatiello; Bashkim Kadriu; Alessandro Guidotti; Erminio Costa
Imidazenil: a low efficacy agonist at alpha1- but high efficacy at alpha5-GABAA receptors fail to show anticonvulsant cross tolerance to diazepam or zolpidem.
Neuropharmacology 2008;55(2):148-53.
2008: Fabio Pibiri; Marianela Nelson; Alessandro Guidotti; Erminio Costa; Graziano Pinna
Decreased corticolimbic allopregnanolone expression during social isolation enhances contextual fear: A model relevant for posttraumatic stress disorder.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(14):5567-72.
2007: Roberto C Agís-Balboa; Graziano Pinna; Fabio Pibiri; Bashkim Kadriu; Erminio Costa; Alessandro Guidotti
Down-regulation of neurosteroid biosynthesis in corticolimbic circuits mediates social isolation-induced behavior in mice.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(47):18736-41.
2007: William Ruzicka; Adrian Zhubi; Marin Veldic; Dennis Grayson; Erminio Costa; Alessandro Guidotti
Selective epigenetic alteration of layer I GABAergic neurons isolated from prefrontal cortex of schizophrenia patients using laser-assisted microdissection.
Molecular psychiatry 2007;12(4):385-97.
2007: Erbo Dong; Alessandro Guidotti; Dennis Grayson; Erminio Costa
Histone hyperacetylation induces demethylation of reelin and 67-kDa glutamic acid decarboxylase promoters.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(11):4676-81.
2007: Marin Veldic; Bashkim Kadriu; Ekrem Maloku; Roberto Carlos Agis-Balboa; Alessandro Guidotti; John M Davis; Erminio Costa
Epigenetic mechanisms expressed in basal ganglia GABAergic neurons differentiate schizophrenia from bipolar disorder.
Schizophrenia research 2007;91(1-3):51-61.
2007: Alessandro Guidotti; William Ruzicka; Dennis Grayson; Marin Veldic; Graziano Pinna; John M Davis; Erminio Costa
S-adenosyl methionine and DNA methyltransferase-1 mRNA overexpression in psychosis.
Neuroreport 2007;18(1):57-60.
2007: Erminio Costa; Erbo Dong; Dennis Grayson; Alessandro Guidotti; William Ruzicka; Marin Veldic
Reviewing the role of DNA (cytosine-5) methyltransferase overexpression in the cortical GABAergic dysfunction associated with psychosis vulnerability.
Epigenetics : official journal of the DNA Methylation Society 2007;2(1):29-36.
2006: Rajiv P Sharma; Cherise Rosen; Saritha Kartan; Alessandro Guidotti; Erminio Costa; Dennis Grayson; Kayla Chase
Valproic acid and chromatin remodeling in schizophrenia and bipolar disorder: preliminary results from a clinical population.
Schizophrenia research 2006;88(1-3):227-31.
2006: Ann M Rasmusson; Graziano Pinna; Prashni Paliwal; David Weisman; Christopher Gottschalk; Dennis Charney; John H Krystal; Alessandro Guidotti
Decreased cerebrospinal fluid allopregnanolone levels in women with posttraumatic stress disorder.
Biological psychiatry 2006;60(7):704-13.
2006: Roberto C Agís-Balboa; Graziano Pinna; Adrian Zhubi; Ekrem Maloku; Marin Veldic; Erminio Costa; Alessandro Guidotti
Characterization of brain neurons that express enzymes mediating neurosteroid biosynthesis.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(39):14602-7.
2006: Dennis Grayson; Ying Chen; Erminio Costa; Erbo Dong; Alessandro Guidotti; Marija Kundakovic; Rajiv P Sharma
The human reelin gene: transcription factors (+), repressors (-) and the methylation switch (+/-) in schizophrenia.
Pharmacology & therapeutics 2006;111(1):272-86.
2006: Graziano Pinna; Erminio Costa; Alessandro Guidotti
Fluoxetine and norfluoxetine stereospecifically and selectively increase brain neurosteroid content at doses that are inactive on 5-HT reuptake.
Psychopharmacology 2006;186(3):362-72.
2006: Graziano Pinna; Roberto Carlos Agis-Balboa; Adrian Zhubi; Kinzo Matsumoto; Dennis Grayson; Erminio Costa; Alessandro Guidotti
Imidazenil and diazepam increase locomotor activity in mice exposed to protracted social isolation.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(11):4275-80.
2006: Maria Vittoria Simonini; L M Camargo; Erbo Dong; Ekrem Maloku; Marin Veldic; Erminio Costa; Alessandro Guidotti
The benzamide MS-275 is a potent, long-lasting brain region-selective inhibitor of histone deacetylases.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(5):1587-92.
2006: Erminio Costa; Erbo Dong; Dennis Grayson; William Ruzicka; Maria Vittoria Simonini; Marin Veldic; Alessandro Guidotti
Epigenetic targets in GABAergic neurons to treat schizophrenia.
Advances in pharmacology (San Diego, Calif.) 2006;54():95-117.
2006: Patricia Tueting; Mohemed-Salim Doueiri; Alessandro Guidotti; John M Davis; Erminio Costa
Reelin down-regulation in mice and psychosis endophenotypes.
Neuroscience and biobehavioral reviews 2006;30(8):1065-77.
2005: James Auta; Erminio Costa; John M Davis; Alessandro Guidotti
Imidazenil: an antagonist of the sedative but not the anticonvulsant action of diazepam.
Neuropharmacology 2005;49(3):425-9.
2005: Erbo Dong; Roberto Carlos Agis-Balboa; Maria Vittoria Simonini; Dennis Grayson; Erminio Costa; Alessandro Guidotti
Reelin and glutamic acid decarboxylase67 promoter remodeling in an epigenetic methionine-induced mouse model of schizophrenia.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(35):12578-83.
2005: Kinzo Matsumoto; Alessandro Guidotti; Erminio Costa
[Stress and sleep/emotional disorder: possible involvement of neurosteroid allopregnanolone].
Nihon yakurigaku zasshi. Folia pharmacologica Japonica 2005;126(2):107-12.
2005: Rajiv P Sharma; Dennis Grayson; Alessandro Guidotti; Erminio Costa
Chromatin, DNA methylation and neuron gene regulation--the purpose of the package.
Journal of psychiatry & neuroscience : JPN 2005;30(4):257-63.
2005: Alessandro Guidotti; James Auta; John M Davis; Erbo Dong; Dennis Grayson; Marin Veldic; Xianquan Zhang; Erminio Costa
GABAergic dysfunction in schizophrenia: new treatment strategies on the horizon.
Psychopharmacology 2005;180(2):191-205.
2005: Dennis Grayson; Xiaomei Jia; Ying Chen; Rajiv P Sharma; Colin P Mitchell; Alessandro Guidotti; Erminio Costa
Reelin promoter hypermethylation in schizophrenia.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(26):9341-6.
2005: Kinzo Matsumoto; Graziano Pinna; Giulia Puia; Alessandro Guidotti; Erminio Costa
Social isolation stress-induced aggression in mice: a model to study the pharmacology of neurosteroidogenesis.
Stress (Amsterdam, Netherlands) 2005;8(2):85-93.
2005: Lucio Tremolizzo; Mohemed-Salim Doueiri; Erbo Dong; Dennis Grayson; John M Davis; Graziano Pinna; Patricia Tueting; Virginia Rodriguez-Menendez; Erminio Costa; Alessandro Guidotti
Valproate corrects the schizophrenia-like epigenetic behavioral modifications induced by methionine in mice.
Biological psychiatry 2005;57(5):500-9.
2005: Erminio Costa; Alessandro Guidotti; Marin Veldić
Should allosteric positive modulators of GABA(A) receptors be tested in the treatment of schizophrenia?
Schizophrenia research 2005;73(2-3):367-8.
2005: Marin Veldic; Alessandro Guidotti; Ekrem Maloku; John M Davis; Erminio Costa
In psychosis, cortical interneurons overexpress DNA-methyltransferase 1.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(6):2152-7.
2005: Graziano Pinna; Erminio Costa; Alessandro Guidotti
Changes in brain testosterone and allopregnanolone biosynthesis elicit aggressive behavior.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(6):2135-40.
2005: Jai Sung Noh; Rajiv P Sharma; Marin Veldic; Alain A Salvacion; Xiaomei Jia; Ying Chen; Erminio Costa; Alessandro Guidotti; Dennis Grayson
DNA methyltransferase 1 regulates reelin mRNA expression in mouse primary cortical cultures.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(5):1749-54.
2004: Giovanni Carboni; Patricia Tueting; Lucio Tremolizzo; Ikuko Sugaya; John M Davis; Erminio Costa; Alessandro Guidotti
Enhanced dizocilpine efficacy in heterozygous reeler mice relates to GABA turnover downregulation.
Neuropharmacology 2004;46(8):1070-81.
2004: Graziano Pinna; Erminio Costa; Alessandro Guidotti
Fluoxetine and norfluoxetine stereospecifically facilitate pentobarbital sedation by increasing neurosteroids.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(16):6222-5.
2004: James Auta; Erminio Costa; John M Davis; Alessandro Guidotti
Imidazenil: a potent and safe protective agent against diisopropyl fluorophosphate toxicity.
Neuropharmacology 2004;46(3):397-403.
2004: Elisabetta Cagetti; Graziano Pinna; Alessandro Guidotti; Kate Baicy; Richard W Olsen
Chronic intermittent ethanol (CIE) administration in rats decreases levels of neurosteroids in hippocampus, accompanied by altered behavioral responses to neurosteroids and memory function.
Neuropharmacology 2004;46(4):570-9.
2004: Marin Veldic; Héctor J Caruncho; Wen-Sheng Liu; John M Davis; R Satta; Dennis Grayson; Alessandro Guidotti; Erminio Costa
DNA-methyltransferase 1 mRNA is selectively overexpressed in telencephalic GABAergic interneurons of schizophrenia brains.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(1):348-53.
2004: Graziano Pinna; Roberto Carlos Agis-Balboa; Mohemed-Salim Doueiri; Alessandro Guidotti; Erminio Costa
Brain neurosteroids in gender-related aggression induced by social isolation.
Critical reviews in neurobiology 2004;16(1-2):75-82.
2004: Erminio Costa; John M Davis; Erbo Dong; Dennis Grayson; Alessandro Guidotti; Lucio Tremolizzo; Marin Veldic
A GABAergic cortical deficit dominates schizophrenia pathophysiology.
Critical reviews in neurobiology 2004;16(1-2):1-23.
2004: Erminio Costa; Dennis Grayson; Marin Veldic; Alessandro Guidotti
Neurochemical basis for an epigenetic vision of synaptic organization.
International review of neurobiology 2004;59():73-91.
2003: Erminio Costa; Dennis Grayson; Alessandro Guidotti
Epigenetic downregulation of GABAergic function in schizophrenia: potential for pharmacological intervention?
Molecular interventions 2003;3(4):220-9.
2003: John Larson; Jeffrey S Hoffman; Alessandro Guidotti; Erminio Costa
Olfactory discrimination learning deficit in heterozygous reeler mice.
Brain research 2003;971(1):40-6.
2003: Erbo Dong; Héctor J Caruncho; Wen-Sheng Liu; Neil R Smalheiser; Dennis Grayson; Erminio Costa; Alessandro Guidotti
A reelin-integrin receptor interaction regulates Arc mRNA translation in synaptoneurosomes.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(9):5479-84.
2003: Graziano Pinna; Erbo Dong; Kinzo Matsumoto; Erminio Costa; Alessandro Guidotti
In socially isolated mice, the reversal of brain allopregnanolone down-regulation mediates the anti-aggressive action of fluoxetine.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(4):2035-40.
2003: Erminio Costa; Dennis Grayson; Colin P Mitchell; Lucio Tremolizzo; Marin Veldic; Alessandro Guidotti
GABAergic cortical neuron chromatin as a putative target to treat schizophrenia vulnerability.
Critical reviews in neurobiology 2003;15(2):121-42.
2003: Giulia Puia; JM Mienville; Kinzo Matsumoto; H Takahata; H Watanabe; Erminio Costa; Alessandro Guidotti
On the putative physiological role of allopregnanolone on GABA(A) receptor function.
Neuropharmacology 2003;44(1):49-55.
2002: Lucio Tremolizzo; Giovanni Carboni; William Ruzicka; Colin P Mitchell; Ikuko Sugaya; Patricia Tueting; Rajiv P Sharma; Dennis Grayson; Erminio Costa; Alessandro Guidotti
An epigenetic mouse model for molecular and behavioral neuropathologies related to schizophrenia vulnerability.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(26):17095-100.
2002: Erminio Costa; James Auta; Dennis Grayson; Kinzo Matsumoto; George D Pappas; X Zhang; Alessandro Guidotti
GABAA receptors and benzodiazepines: a role for dendritic resident subunit mRNAs.
Neuropharmacology 2002;43(6):925-37.
2002: Miguel A Rodriguez; Héctor J Caruncho; Erminio Costa; Christine Pesold; Wen-Sheng Liu; Alessandro Guidotti
In Patas monkey, glutamic acid decarboxylase-67 and reelin mRNA coexpression varies in a manner dependent on layers and cortical areas.
The Journal of comparative neurology 2002;451(3):279-88.
2002: H M Kim; Tingyu Qu; Virginia Kriho; Pascale LACOR; Neil R Smalheiser; George D Pappas; Alessandro Guidotti; Erminio Costa; Kiminobu Sugaya
Reelin function in neural stem cell biology.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(6):4020-5.
2002: Erminio Costa; Ying Chen; John M Davis; Erbo Dong; Jai Sung Noh; Lucio Tremolizzo; Marin Veldic; Dennis Grayson; Alessandro Guidotti
REELIN and schizophrenia: a disease at the interface of the genome and the epigenome.
Molecular interventions 2002;2(1):47-57.
2002: Erminio Costa; John M Davis; Christine Pesold; Patricia Tueting; Alessandro Guidotti
The heterozygote reeler mouse as a model for the development of a new generation of antipsychotics.
Current opinion in pharmacology 2002;2(1):56-62.
2002: H Zhang; X Liu; C Zhang; E Mundo; F Macciardi; Dennis Grayson; Alessandro Guidotti; Jeanette J A Holden
Reelin gene alleles and susceptibility to autism spectrum disorders.
Molecular psychiatry 2002;7(9):1012-7.
2001: Alessandro Guidotti; Erbo Dong; Kinzo Matsumoto; Graziano Pinna; A M Rasmusson; Erminio Costa
The socially-isolated mouse: a model to study the putative role of allopregnanolone and 5alpha-dihydroprogesterone in psychiatric disorders.
Brain research. Brain research reviews 2001;37(1-3):110-5.
2001: Erminio Costa; John M Davis; Dennis Grayson; Alessandro Guidotti; George D Pappas; Christine Pesold
Dendritic spine hypoplasticity and downregulation of reelin and GABAergic tone in schizophrenia vulnerability.
Neurobiology of disease 2001;8(5):723-42.
2001: Esa R Korpi; Rauno Mäkelä; Elena Romeo; Alessandro Guidotti; Mikko Uusi-Oukari; C Furnari; Flavia di Michele; Maija Sarviharju; M Xu; P H Rosenberg
Increased behavioral neurosteroid sensitivity in a rat line selectively bred for high alcohol sensitivity.
European journal of pharmacology 2001;421(1):31-8.
2001: E Izzo; James Auta; F Impagnatiello; Christine Pesold; Alessandro Guidotti; Erminio Costa
Glutamic acid decarboxylase and glutamate receptor changes during tolerance and dependence to benzodiazepines.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(6):3483-8.
2001: Wen-Sheng Liu; Christine Pesold; Miguel A Rodriguez; Giovanni Carboni; James Auta; Pascale LACOR; John Larson; Brian G Condie; Alessandro Guidotti; Erminio Costa
Down-regulation of dendritic spine and glutamic acid decarboxylase 67 expressions in the reelin haploinsufficient heterozygous reeler mouse.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(6):3477-82.
2001: Erbo Dong; Kinzo Matsumoto; Veska Uzunova; Ikuko Sugaya; H Takahata; H Nomura; H Watanabe; Erminio Costa; Alessandro Guidotti
Brain 5alpha-dihydroprogesterone and allopregnanolone synthesis in a mouse model of protracted social isolation.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(5):2849-54.
2000: Alessandro Guidotti; James Auta; John M Davis; V Di-Giorgi-Gerevini; Yogesh Dwivedi; Dennis Grayson; F Impagnatiello; Ghanshyam N Pandey; Christine Pesold; Rajiv P Sharma; Doncho P Uzunov; Erminio Costa; V DiGiorgi Gerevini
Decrease in reelin and glutamic acid decarboxylase67 (GAD67) expression in schizophrenia and bipolar disorder: a postmortem brain study.
Archives of general psychiatry 2000;57(11):1061-9.
2000: Alessandro Guidotti; Christine Pesold; Erminio Costa
New neurochemical markers for psychosis: a working hypothesis of their operation.
Neurochemical research 2000;25(9-10):1207-18.
2000: James Auta; D Lecca; M Nelson; Alessandro Guidotti; David H Overstreet; Erminio Costa; Javaid I Javaid
Expression and function of striatal nAChRs differ in the flinders sensitive (FSL) and resistant (FRL) rat lines.
Neuropharmacology 2000;39(13):2624-31.
2000: Miguel A Rodriguez; Christine Pesold; Wen-Sheng Liu; Virginia Kriho; Alessandro Guidotti; George D Pappas; Erminio Costa
Colocalization of integrin receptors and reelin in dendritic spine postsynaptic densities of adult nonhuman primate cortex.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(7):3550-5.
2000: Pascale LACOR; Dennis Grayson; James Auta; Ikuko Sugaya; Erminio Costa; Alessandro Guidotti
Reelin secretion from glutamatergic neurons in culture is independent from neurotransmitter regulation.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(7):3556-61.
2000: James Auta; Alessandro Guidotti; Erminio Costa
Imidazenil prevention of alprazolam-induced acquisition deficit in patas monkeys is devoid of tolerance.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(5):2314-9.
2000: Neil R Smalheiser; Erminio Costa; Alessandro Guidotti; F Impagnatiello; James Auta; Pascale LACOR; Virginia Kriho; George D Pappas
Expression of reelin in adult mammalian blood, liver, pituitary pars intermedia, and adrenal chromaffin cells.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(3):1281-6.
2000: Graziano Pinna; Veska Uzunova; Kinzo Matsumoto; Giulia Puia; JM Mienville; Erminio Costa; Alessandro Guidotti
Brain allopregnanolone regulates the potency of the GABA(A) receptor agonist muscimol.
Neuropharmacology 2000;39(3):440-8.
1999: Robert M Mihalek; P K Banerjee; Esa R Korpi; Joseph J Quinlan; Leonard L Firestone; ZP Mi; Carl F Lagenaur; Verena Tretter; Werner Sieghart; Stephan Anagnostaras; J R Sage; Michael S Fanselow; Alessandro Guidotti; Igor Spigelman; Z Li; Timothy M DeLorey; Richard W Olsen; Gregg E Homanics
Attenuated sensitivity to neuroactive steroids in gamma-aminobutyrate type A receptor delta subunit knockout mice.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(22):12905-10.
1999: Mitsuo Saito; M Saito; Martin J Berg; Alessandro Guidotti; Neville Marks
Gangliosides attenuate ethanol-induced apoptosis in rat cerebellar granule neurons.
Neurochemical research 1999;24(9):1107-15.
1999: James Auta; P Longone; Alessandro Guidotti; Erminio Costa
The regulation of hippocampal nicotinic acetylcholine receptors (nAChRs) after a protracted treatment with selective or nonselective nAChR agonists.
Journal of molecular neuroscience : MN 1999;13(1-2):31-45.
1999: Kinzo Matsumoto; Veska Uzunova; Graziano Pinna; K Taki; Doncho P Uzunov; H Watanabe; JM Mienville; Alessandro Guidotti; Erminio Costa
Permissive role of brain allopregnanolone content in the regulation of pentobarbital-induced righting reflex loss.
Neuropharmacology 1999;38(7):955-63.
1999: Patricia Tueting; Erminio Costa; Yogesh Dwivedi; Alessandro Guidotti; F Impagnatiello; Radmila Manev; Christine Pesold
The phenotypic characteristics of heterozygous reeler mouse.
Neuroreport 1999;10(6):1329-34.
1999: Christine Pesold; Wen-Sheng Liu; Alessandro Guidotti; Erminio Costa; Héctor J Caruncho
Cortical bitufted, horizontal, and Martinotti cells preferentially express and secrete reelin into perineuronal nets, nonsynaptically modulating gene expression.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(6):3217-22.
1998: F Impagnatiello; Alessandro Guidotti; Christine Pesold; Yogesh Dwivedi; Héctor J Caruncho; MG Pisu; Doncho P Uzunov; Neil R Smalheiser; John M Davis; Ghanshyam N Pandey; George D Pappas; Patricia Tueting; Rajiv P Sharma; Erminio Costa
A decrease of reelin expression as a putative vulnerability factor in schizophrenia.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(26):15718-23.
1998: Alessandro Guidotti; Erminio Costa
Can the antidysphoric and anxiolytic profiles of selective serotonin reuptake inhibitors be related to their ability to increase brain 3 alpha, 5 alpha-tetrahydroprogesterone (allopregnanolone) availability?
Biological psychiatry 1998;44(9):865-73.
1998: M Giorgetti; Javaid I Javaid; John M Davis; Erminio Costa; Alessandro Guidotti; Sarah B Appel; Mark S Brodie
Imidazenil, a positive allosteric GABAA receptor modulator, inhibits the effects of cocaine on locomotor activity and extracellular dopamine in the nucleus accumbens shell without tolerance liability.
The Journal of pharmacology and experimental therapeutics 1998;287(1):58-66.
1998: Y Liao; Alan P Kozikowski; Alessandro Guidotti; Erminio Costa
Synthesis and pharmacological evaluation of benzofuran-acetamides as "antineophobic" mitochondrial DBI receptor complex ligands.
Bioorganic & medicinal chemistry letters 1998;8(16):2099-102.
1998: P Longone; F Impagnatiello; JM Mienville; Erminio Costa; Alessandro Guidotti
Changes in AMPA receptor-spliced variant expression and shift in AMPA receptor spontaneous desensitization pharmacology during cerebellar granule cell maturation in vitro.
Journal of molecular neuroscience : MN 1998;11(1):23-41.
1998: Mitsuo Saito; Alessandro Guidotti; Martin J Berg; Neville Marks
The semisynthetic glycosphingolipid LIGA20 potently protects neurons against apoptosis.
Annals of the New York Academy of Sciences 1998;845():253-62.
1998: Neville Marks; Martin J Berg; Alessandro Guidotti; Mitsuo Saito
Activation of caspase-3 and apoptosis in cerebellar granule cells.
Journal of neuroscience research 1998;52(3):334-41.
1998: Veska Uzunova; Y Sheline; John M Davis; A Rasmusson; Doncho P Uzunov; Erminio Costa; Alessandro Guidotti
Increase in the cerebrospinal fluid content of neurosteroids in patients with unipolar major depression who are receiving fluoxetine or fluvoxamine.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(6):3239-44.
1998: Christine Pesold; F Impagnatiello; MG Pisu; Doncho P Uzunov; Erminio Costa; Alessandro Guidotti; Héctor J Caruncho
Reelin is preferentially expressed in neurons synthesizing gamma-aminobutyric acid in cortex and hippocampus of adult rats.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(6):3221-6.
1997: Christine Pesold; Héctor J Caruncho; F Impagnatiello; M J Berg; J M Fritschy; Alessandro Guidotti; Erminio Costa
Tolerance to diazepam and changes in GABA(A) receptor subunit expression in rat neocortical areas.
Neuroscience 1997;79(2):477-87.
1997: F Impagnatiello; A Oberto; P Longone; Erminio Costa; Alessandro Guidotti
7-Chloro-3-methyl-3,4-dihydro-2H-1,2,4-benzothiadiazine S,S-dioxide: a partial modulator of AMPA receptor desensitization devoid of neurotoxicity.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(13):7053-8.
1997: Héctor J Caruncho; Alessandro Guidotti; J Lindstrom; Erminio Costa; Christine Pesold
Subcellular localization of the alpha 7 nicotinic receptor in rat cerebellar granule cell layer.
Neuroreport 1997;8(6):1431-3.
1996: Doncho P Uzunov; T B Cooper; Erminio Costa; Alessandro Guidotti
Fluoxetine-elicited changes in brain neurosteroid content measured by negative ion mass fragmentography.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(22):12599-604.
1996: A Oberto; N Marks; H L Evans; Alessandro Guidotti
Lead (Pb+2) promotes apoptosis in newborn rat cerebellar neurons: pathological implications.
The Journal of pharmacology and experimental therapeutics 1996;279(1):435-42.
1996: A Arai; Alessandro Guidotti; E Costa; Gary Lynch
Effect of the AMPA receptor modulator IDRA 21 on LTP in hippocampal slices.
Neuroreport 1996;7(13):2211-5.
1996: B Adinoff; Raymond F Anton; M Linnoila; Alessandro Guidotti; Charles Nemeroff; Garth Bissette
Cerebrospinal fluid concentrations of corticotropin-releasing hormone (CRH) and diazepam-binding inhibitor (DBI) during alcohol withdrawal and abstinence.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 1996;15(3):288-95.
1996: Erminio Costa; Alessandro Guidotti
Benzodiazepines on trial: a research strategy for their rehabilitation.
Trends in pharmacological sciences 1996;17(5):192-200.
1996: F Impagnatiello; Christine Pesold; P Longone; Héctor J Caruncho; J M Fritschy; Erminio Costa; Alessandro Guidotti
Modifications of gamma-aminobutyric acidA receptor subunit expression in rat neocortex during tolerance to diazepam.
Molecular pharmacology 1996;49(5):822-31.
1996: P Longone; F Impagnatiello; Alessandro Guidotti; Erminio Costa
Reversible modification of GABAA receptor subunit mRNA expression during tolerance to diazepam-induced cognition dysfunction.
Neuropharmacology 1996;35(9-10):1465-73.
1996: Héctor J Caruncho; I Liste; Christine Pesold; F Impagnatiello; Alessandro Guidotti; Jose L Labandeira-Garcia
Semiquantitative immunocytochemical analysis of GABAA receptor subunit expression in the rat neostriatum.
Receptors & channels 1996;4(2):85-92.
1995: D L Cheney; D Uzunov; Alessandro Guidotti
Pregnenolone sulfate antagonizes dizocilpine amnesia: role for allopregnanolone.
Neuroreport 1995;6(12):1697-700.
1995: D M Thompson; Alessandro Guidotti; M DiBella; Erminio Costa
7-Chloro-3-methyl-3,4-dihydro-2H-1,2,4-benzothiadiazine S,S-dioxide (IDRA 21), a congener of aniracetam, potently abates pharmacologically induced cognitive impairments in patas monkeys.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(17):7667-71.
1995: D P Uzunov; I Zivkovich; W H Pirkle; Erminio Costa; Alessandro Guidotti
Enantiomeric resolution with a new chiral stationary phase of 7-chloro-3-methyl-3,4-dihydro-2H-1,2,4-benzothiadiazine S,S-dioxide, a cognition-enhancing benzothiadiazine derivative.
Journal of pharmaceutical sciences 1995;84(8):937-42.
1995: D M Thompson; J Auta; Alessandro Guidotti; Erminio Costa
Imidazenil, a new anxiolytic and anticonvulsant drug, attenuates a benzodiazepine-induced cognition deficit in monkeys.
The Journal of pharmacology and experimental therapeutics 1995;273(3):1307-12.
1995: D L Cheney; D Uzunov; Erminio Costa; Alessandro Guidotti
Gas chromatographic-mass fragmentographic quantitation of 3 alpha-hydroxy-5 alpha-pregnan-20-one (allopregnanolone) and its precursors in blood and brain of adrenalectomized and castrated rats.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1995;15(6):4641-50.
1995: P De Stefanis; F Impagnatiello; A Berkovich; Alessandro Guidotti
Inhibitory effect of ODN, a naturally occurring processing product of diazepam binding inhibitor, on secretagogues-induced insulin secretion.
Regulatory peptides 1995;56(2-3):153-65.
1995: I Zivkovic; D M Thompson; M Bertolino; D Uzunov; M DiBella; Erminio Costa; Alessandro Guidotti
7-Chloro-3-methyl-3-4-dihydro-2H-1,2,4 benzothiadiazine S,S-dioxide (IDRA 21): a benzothiadiazine derivative that enhances cognition by attenuating DL-alpha-amino-2,3-dihydro-5-methyl-3-oxo-4-isoxazolepropanoic acid (AMPA) receptor desensitization.
The Journal of pharmacology and experimental therapeutics 1995;272(1):300-9.
1995: Erminio Costa; J Auta; Héctor J Caruncho; Alessandro Guidotti; F Impagnatiello; Christine Pesold; D M Thompson
A search for a new anticonvulsant and anxiolytic benzodiazepine devoid of side effects and tolerance liability.
Advances in biochemical psychopharmacology 1995;48():75-92.
1994: R J Hawley; Charles Nemeroff; Garth Bissette; Alessandro Guidotti; R Rawlings; M Linnoila
Neurochemical correlates of sympathetic activation during severe alcohol withdrawal.
Alcoholism, clinical and experimental research 1994;18(6):1312-6.
1994: Erminio Costa; D L Cheney; Dennis Grayson; A Korneyev; P Longone; L Pani; E Romeo; E Zivkovich; Alessandro Guidotti
Pharmacology of neurosteroid biosynthesis. Role of the mitochondrial DBI receptor (MDR) complex.
Annals of the New York Academy of Sciences 1994;746():223-42.
1994: J Auta; Pietro Giusti; Alessandro Guidotti; Erminio Costa
Imidazenil, a partial positive allosteric modulator of GABAA receptors, exhibits low tolerance and dependence liabilities in the rat.
The Journal of pharmacology and experimental therapeutics 1994;270(3):1262-9.
1994: A Kharlamov; I Zivkovic; A Polo; D M Armstrong; Erminio Costa; Alessandro Guidotti
LIGA20, a lyso derivative of ganglioside GM1, given orally after cortical thrombosis reduces infarct size and associated cognition deficit.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(14):6303-7.
1994: E Romeo; D L Cheney; I Zivkovic; Erminio Costa; Alessandro Guidotti
Mitochondrial diazepam-binding inhibitor receptor complex agonists antagonize dizocilpine amnesia: putative role for allopregnanolone.
The Journal of pharmacology and experimental therapeutics 1994;270(1):89-96.
1994: Erminio Costa; J Auta; Alessandro Guidotti; A Korneyev; E Romeo
The pharmacology of neurosteroidogenesis.
The Journal of steroid biochemistry and molecular biology 1994;49(4-6):385-9.
1994: Mark Stork George; Alessandro Guidotti; David Rubinow; B Pan; K Mikalauskas; Robert M Post
CSF neuroactive steroids in affective disorders: pregnenolone, progesterone, and DBI.
Biological psychiatry 1994;35(10):775-80.
1994: M A Perillo; Alessandro Guidotti; E Costa; Robert K Yu; Bruno Maggio
Modulation of phospholipases A2 and C activities against dilauroylphosphorylcholine in mixed monolayers with semisynthetic derivatives of ganglioside and sphingosine.
Molecular membrane biology 1994;11(2):119-26.
1994: Erminio Costa; D M Armstrong; Alessandro Guidotti; A Kharlamov; Lech Kiedrowski; Hari Manev; A Polo; Jarda T Wroblewski
Gangliosides in the protection against glutamate excitotoxicity.
Progress in brain research 1994;101():357-73.
1994: A Polo; G Kirschner; Alessandro Guidotti; Erminio Costa
Brain content of glycosphingolipids after oral administration of monosialogangliosides GM1 and LIGA20 to rats.
Molecular and chemical neuropathology / sponsored by the International Society for Neurochemistry and the World Federation of Neurology and research groups on neurochemistry and cerebrospinal fluid 1994;21(1):41-53.
1994: R A Rius; Alessandro Guidotti; Erminio Costa
Pituitary adenylate cyclase activating polypeptide (PACAP) potently enhances tyrosine hydroxylase (TH) expression in adrenal chromaffin cells.
Life sciences 1994;54(22):1735-43.
1994: Daniel P van Kammen; Alessandro Guidotti; Thomas Neylan; P Guarneri; ME Kelley; John A Gurklis; M W Gilbertson; J L Peters; E Costa
CSF levels of diazepam-binding inhibitor correlate with REM latency in schizophrenia, a pilot study.
European archives of psychiatry and clinical neuroscience 1994;244(4):216-22.
1994: Matti Virkkunen; Erkki A Kallio; Robert R Rawlings; R Tokola; Russell Poland; Alessandro Guidotti; Charles Nemeroff; Garth Bissette; K Kalogeras; S L Karonen
Personality profiles and state aggressiveness in Finnish alcoholic, violent offenders, fire setters, and healthy volunteers.
Archives of general psychiatry 1994;51(1):28-33.
1994: Matti Virkkunen; Robert R Rawlings; R Tokola; Russell Poland; Alessandro Guidotti; Charles Nemeroff; Garth Bissette; K Kalogeras; S L Karonen; Markku Linnoila
CSF biochemistries, glucose metabolism, and diurnal activity rhythms in alcoholic, violent offenders, fire setters, and healthy volunteers.
Archives of general psychiatry 1994;51(1):20-7.
1993: A Korneyev; Alessandro Guidotti; Erminio Costa
Regional and interspecies differences in brain progesterone metabolism.
Journal of neurochemistry 1993;61(6):2041-7.
1993: Daniel P van Kammen; Alessandro Guidotti; ME Kelley; John A Gurklis; P Guarneri; M W Gilbertson; Jeffrey K Yao; J Peters; E Costa
CSF diazepam binding inhibitor and schizophrenia: clinical and biochemical relationships.
Biological psychiatry 1993;34(8):515-22.
1993: Alan P Kozikowski; Dawei Ma; J Brewer; S Sun; Erminio Costa; E Romeo; Alessandro Guidotti
Chemistry, binding affinities, and behavioral properties of a new class of "antineophobic" mitochondrial DBI receptor complex (mDRC) ligands.
Journal of medicinal chemistry 1993;36(20):2908-20.
1993: A Korneyev; B S Pan; A Polo; E Romeo; Alessandro Guidotti; Erminio Costa
Stimulation of brain pregnenolone synthesis by mitochondrial diazepam binding inhibitor receptor ligands in vivo.
Journal of neurochemistry 1993;61(4):1515-24.
1993: M A Perillo; A Polo; Alessandro Guidotti; E Costa; Bruno Maggio
Molecular parameters of semisynthetic derivatives of gangliosides and sphingosine in monolayers at the air-water interface.
Chemistry and physics of lipids 1993;65(3):225-38.
1993: E Romeo; S Cavallaro; A Korneyev; Alan P Kozikowski; Dawei Ma; A Polo; Erminio Costa; Alessandro Guidotti
Stimulation of brain steroidogenesis by 2-aryl-indole-3-acetamide derivatives acting at the mitochondrial diazepam-binding inhibitor receptor complex.
The Journal of pharmacology and experimental therapeutics 1993;267(1):462-71.
1993: Pietro Giusti; I Ducić; G Puia; R Arban; A Walser; Alessandro Guidotti; Erminio Costa
Imidazenil: a new partial positive allosteric modulator of gamma-aminobutyric acid (GABA) action at GABAA receptors.
The Journal of pharmacology and experimental therapeutics 1993;266(2):1018-28.
1993: A Kharlamov; Alessandro Guidotti; Erminio Costa; R Hayes; D Armstrong
Semisynthetic sphingolipids prevent protein kinase C translocation and neuronal damage in the perifocal area following a photochemically induced thrombotic brain cortical lesion.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1993;13(6):2483-94.
1993: J Auta; E Romeo; Alan P Kozikowski; Dawei Ma; Erminio Costa; Alessandro Guidotti
Participation of mitochondrial diazepam binding inhibitor receptors in the anticonflict, antineophobic and anticonvulsant action of 2-aryl-3-indoleacetamide and imidazopyridine derivatives.
The Journal of pharmacology and experimental therapeutics 1993;265(2):649-56.
1993: G Lombardi; A M Szekely; L A Bristol; Alessandro Guidotti; Hari Manev
Induction of ornithine decarboxylase by N-methyl-D-aspartate receptor activation is unrelated to potentiation of glutamate excitotoxicity by polyamines in cerebellar granule neurons.
Journal of neurochemistry 1993;60(4):1317-24.
1993: A Y Korneyev; Erminio Costa; Alessandro Guidotti
During anesthetic-induced activation of hypothalamic pituitary adrenal axis, blood-borne steroids fail to contribute to the anesthetic effect.
Neuroendocrinology 1993;57(3):559-65.
1993: S Cavallaro; L Pani; Alessandro Guidotti; Erminio Costa
ACTH-induced mitochondrial DBI receptor (MDR) and diazepam binding inhibitor (DBI) expression in adrenals of hypophysectomized rats is not cause-effect related to its immediate steroidogenic action.
Life sciences 1993;53(14):1137-47.
1993: A Berkovich; Carlo Ferrarese; Guido Cavaletti; Hannu Alho; C Marzorati; G Bianchi; Alessandro Guidotti; Erminio Costa
Topology of two DBI receptors in human lymphocytes.
Life sciences 1993;52(15):1265-77.
1993: Hari Manev; Alessandro Guidotti; Erminio Costa
Protection by gangliosides against glutamate excitotoxicity.
Advances in lipid research 1993;25():269-88.
1993: Erminio Costa; D Armstrong; Alessandro Guidotti; A Kharlamov; Lech Kiedrowski; Jarda T Wroblewski
Ganglioside GM1 and its semisynthetic lysogangliosides reduce glutamate neurotoxicity by a novel mechanism.
Advances in experimental medicine and biology 1993;341():129-41.
1992: S Cavallaro; A Korneyev; Alessandro Guidotti; Erminio Costa
Diazepam-binding inhibitor (DBI)-processing products, acting at the mitochondrial DBI receptor, mediate adrenocorticotropic hormone-induced steroidogenesis in rat adrenal gland.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(22):10598-602.
1992: Jeffrey rothstein; Alessandro Guidotti; Paolo Tinuper; Pietro Cortelli; Patrizia Avoni; Giuseppe Plazzi; Elio Lugaresi; P Schoch; Pasquale Montagna
Endogenous benzodiazepine receptor ligands in idiopathic recurring stupor.
Lancet 1992;340(8826):1002-4.
1992: E Romeo; J Auta; Alan P Kozikowski; Dawei Ma; Vassilios Papadopoulos; G Puia; Erminio Costa; Alessandro Guidotti
2-Aryl-3-indoleacetamides (FGIN-1): a new class of potent and specific ligands for the mitochondrial DBI receptor (MDR).
The Journal of pharmacology and experimental therapeutics 1992;262(3):971-8.
1992: Jeffrey rothstein; Alessandro Guidotti; Erminio Costa
Release of endogenous benzodiazepine receptor ligands (endozepines) from cultured neurons.
Neuroscience letters 1992;143(1-2):210-4.
1992: E Costa; A Kharlamov; Alessandro Guidotti; R Hayes; D Armstrong
Sequelae of biochemical events following photochemical injury of rat sensory-motor cortex: mechanism of ganglioside protection.
Patologicheskaia fiziologiia i èksperimental'naia terapiia 1992;(4):17-23.
1992: Vassilios Papadopoulos; Patrizia Guarneri; K E Kreuger; Alessandro Guidotti; Erminio Costa
Pregnenolone biosynthesis in C6-2B glioma cell mitochondria: regulation by a mitochondrial diazepam binding inhibitor receptor.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(11):5113-7.
1992: Jeffrey rothstein; W Garland; G Puia; Alessandro Guidotti; Richard J. Weber; Erminio Costa
Purification and characterization of naturally occurring benzodiazepine receptor ligands in rat and human brain.
Journal of neurochemistry 1992;58(6):2102-15.
1992: M Olasmaa; Alessandro Guidotti; Erminio Costa
Vasoactive intestinal polypeptide facilitates tyrosine hydroxylase induction by cholinergic agonists in bovine adrenal chromaffin cells.
Molecular pharmacology 1992;41(3):456-64.
1992: Pietro Giusti; E Romeo; J Auta; Alessandro Guidotti
Structural variety of GABAA receptors and specificity of benzodiazepines pharmacological profiles.
Advances in biochemical psychopharmacology 1992;47():163-77.
1991: Alessandro Guidotti
Role of DBI in brain and its posttranslational processing products in normal and abnormal behavior.
Neuropharmacology 1991;30(12B):1425-33.
1991: Hari Manev; M Favaron; R Siman; Alessandro Guidotti; Erminio Costa
Glutamate neurotoxicity is independent of calpain I inhibition in primary cultures of cerebellar granule cells.
Journal of neurochemistry 1991;57(4):1288-95.
1991: Vassilios Papadopoulos; A Berkovich; Karl E Krueger; Erminio Costa; Alessandro Guidotti
Diazepam binding inhibitor and its processing products stimulate mitochondrial steroid biosynthesis via an interaction with mitochondrial benzodiazepine receptors.
Endocrinology 1991;129(3):1481-8.
1991: Carlo Ferrarese; Alessandro Guidotti; E Costa; R S Miletich; Kenner C Rice; B R de Costa; M J Fulham; G Di Chiro
In vivo study of NMDA-sensitive glutamate receptor by fluorothienylcyclohexylpiperidine [correction of fluorothienylcycloexylpiperidine], a possible ligand for positron emission tomography.
Neuropharmacology 1991;30(8):899-905.
1991: M Massotti; E Slobodyansky; D Konkel; Erminio Costa; Alessandro Guidotti
Regulation of diazepam binding inhibitor in rat adrenal gland by adrenocorticotropin.
Endocrinology 1991;129(2):591-6.
1991: Pietro Giusti; G Guidetti; Erminio Costa; Alessandro Guidotti
The preferential antagonism of pentylenetetrazole proconflict responses differentiates a class of anxiolytic benzodiazepines with potential antipanic action.
The Journal of pharmacology and experimental therapeutics 1991;257(3):1062-8.
1991: M Massotti; J L Schlichting; M D Antonacci; Pietro Giusti; Maurizio Memo; Erminio Costa; Alessandro Guidotti
gamma-Aminobutyric acidA receptor heterogeneity in rat central nervous system: studies with clonazepam and other benzodiazepine ligands.
The Journal of pharmacology and experimental therapeutics 1991;256(3):1154-60.
1991: Erminio Costa; Alessandro Guidotti
Diazepam binding inhibitor (DBI): a peptide with multiple biological actions.
Life sciences 1991;49(5):325-44.
1990: M Olasmaa; Jeffrey rothstein; Alessandro Guidotti; Richard J. Weber; S M Paul; S Spector; Maria Luisa Zeneroli; Mario Baraldi; Erminio Costa
Endogenous benzodiazepine receptor ligands in human and animal hepatic encephalopathy.
Journal of neurochemistry 1990;55(6):2015-23.
1990: Gabriel de Erausquin; Hari Manev; Alessandro Guidotti; Erminio Costa; Gary Brooker
Gangliosides normalize distorted single-cell intracellular free Ca2+ dynamics after toxic doses of glutamate in cerebellar granule cells.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(20):8017-21.
1990: Patrizia Bovolin; J Schlichting; M Miyata; Carlo Ferrarese; Alessandro Guidotti; Hannu Alho
Distribution and characterization of diazepam binding inhibitor (DBI) in peripheral tissues of rat.
Regulatory peptides 1990;29(2-3):267-81.
1990: Hari Manev; Erminio Costa; Jarda T Wroblewski; Alessandro Guidotti
Abusive stimulation of excitatory amino acid receptors: a strategy to limit neurotoxicity.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1990;4(10):2789-97.
1990: Patrizia Guarneri; A Berkovich; Alessandro Guidotti; Erminio Costa
A study of diazepam binding inhibitor (DBI) processing products in human cerebrospinal fluid and in postmortem human brain.
Neuropharmacology 1990;29(5):419-28.
1990: A Roy; J DeJong; B Adinoff; M Barbaccia; E Costa; Alessandro Guidotti; Markku Linnoila
CSF diazepam-binding inhibitor in alcoholics and normal controls.
Psychiatry research 1990;31(3):261-6.
1990: M Favaron; Hari Manev; R Siman; M Bertolino; A M Szekely; G DeErausquin; Alessandro Guidotti; Erminio Costa
Down-regulation of protein kinase C protects cerebellar granule neurons in primary culture from glutamate-induced neuronal death.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(5):1983-7.
1990: A Berkovich; P McPhie; M Campagnone; Alessandro Guidotti; P Hensley
A natural processing product of rat diazepam binding inhibitor, triakontatetraneuropeptide (diazepam binding inhibitor 17-50) contains an alpha-helix, which allows discrimination between benzodiazepine binding site subtypes.
Molecular pharmacology 1990;37(2):164-72.
1990: Patrizia Guarneri; Alessandro Guidotti; Erminio Costa
On the processing of diazepam binding inhibitor (DBI) in human brain.
Advances in biochemical psychopharmacology 1990;46():201-11.
1990: Hari Manev; M Favaron; G De Erausquin; Alessandro Guidotti; Gary Brooker; Erminio Costa
Destabilization of ionized Ca2+ homeostasis in excitatory amino acid neurotoxicity: antagonism by glycosphingolipids.
Cell biology international reports 1990;14(1):3-14.
1990: Hari Manev; M Favaron; Stefano Vicini; Alessandro Guidotti
Ganglioside-mediated protection from glutamate-induced neuronal death.
Acta neurobiologiae experimentalis 1990;50(4-5):475-88.
1990: Alessandro Guidotti; Hari Manev; M Favaron; Gary Brooker; Erminio Costa
Protection by natural and semisynthetic gangliosides from Ca2(+)-dependent neurotoxicity caused by excitatory amino acid (EAA) neurotransmitters.
Advances in experimental medicine and biology 1990;268():135-44.
1990: Alessandro Guidotti; M D Antonacci; Pietro Giusti; M Massotti; Maurizio Memo; J L Schlichting
The differences in the pharmacological profiles of various benzodiazepine recognition site ligands may be associated with GABAA receptor structural diversity.
Advances in biochemical psychopharmacology 1990;46():73-87.
1990: Karl E Krueger; A G Mukhin; L Antkiewicz-Michaluk; M R Santi; Dennis Grayson; Alessandro Guidotti; Rolf Sprengel; P Werner; Peter H Seeburg
Purification, cloning, and expression of a peripheral-type benzodiazepine receptor.
Advances in biochemical psychopharmacology 1990;46():1-13.
1990: Hari Manev; M Favaron; Stefano Vicini; Alessandro Guidotti; Erminio Costa
Glutamate-induced neuronal death in primary cultures of cerebellar granule cells: protection by synthetic derivatives of endogenous sphingolipids.
The Journal of pharmacology and experimental therapeutics 1990;252(1):419-27.
1989: Rolf Sprengel; P Werner; Peter H Seeburg; A G Mukhin; M R Santi; Dennis Grayson; Alessandro Guidotti; Karl E Krueger
Molecular cloning and expression of cDNA encoding a peripheral-type benzodiazepine receptor.
The Journal of biological chemistry 1989;264(34):20415-21.
1989: Hannu Alho; Patrizia Bovolin; D Jenkins; Alessandro Guidotti; Erminio Costa
Cellular and subcellular localization of an octadecaneuropeptide derived from diazepam binding inhibitor: immunohistochemical studies in the rat brain.
Journal of chemical neuroanatomy 1989;2(6):301-18.
1989: E Slobodyansky; Alessandro Guidotti; C Wambebe; A Berkovich; Erminio Costa
Isolation and characterization of a rat brain triakontatetraneuropeptide, a posttranslational product of diazepam binding inhibitor: specific action at the Ro 5-4864 recognition site.
Journal of neurochemistry 1989;53(4):1276-84.
1989: A Roy; DAVID PICKAR; P Gold; M Barbaccia; Alessandro Guidotti; E Costa; Markku Linnoila
Diazepam-binding inhibitor and corticotropin-releasing hormone in cerebrospinal fluid.
Acta psychiatrica Scandinavica 1989;80(3):287-91.
1989: Hari Manev; M Favaron; Alessandro Guidotti; Erminio Costa
Delayed increase of Ca2+ influx elicited by glutamate: role in neuronal death.
Molecular pharmacology 1989;36(1):106-12.
1989: Jeffrey rothstein; Guy M McKhann; Patrizia Guarneri; M L Barbaccia; Alessandro Guidotti; Erminio Costa
Cerebrospinal fluid content of diazepam binding inhibitor in chronic hepatic encephalopathy.
Annals of neurology 1989;26(1):57-62.
1989: M Olasmaa; Alessandro Guidotti; Erminio Costa; Jeffrey rothstein; M E Goldman; Richard J. Weber; S M Paul
Endogenous benzodiazepines in hepatic encephalopathy.
Lancet 1989;1(8636):491-2.
1989: Richard A Gillis; I J Namath; C Easington; T Patrick Abrahams; Alessandro Guidotti; J A Quest; Paul Hamosh; A M Taveira da Silva
Drug interaction with gamma-aminobutyric acid/benzodiazepine receptors at the ventral surface of the medulla results in pronounced changes in cardiorespiratory activity.
The Journal of pharmacology and experimental therapeutics 1989;248(2):863-70.
1988: L Antkiewicz-Michaluk; A G Mukhin; Alessandro Guidotti; Karl E Krueger
Purification and characterization of a protein associated with peripheral-type benzodiazepine binding sites.
The Journal of biological chemistry 1988;263(33):17317-21.
1988: M Favaron; Hari Manev; Hannu Alho; M Bertolino; B Ferret; Alessandro Guidotti; Erminio Costa
Gangliosides prevent glutamate and kainate neurotoxicity in primary neuronal cultures of neonatal rat cerebellum and cortex.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(19):7351-5.
1988: L Antkiewicz-Michaluk; Alessandro Guidotti; Karl E Krueger
Molecular characterization and mitochondrial density of a recognition site for peripheral-type benzodiazepine ligands.
Molecular pharmacology 1988;34(3):272-8.
1988: M R Santi; D H Cox; Alessandro Guidotti
Heterogeneity of gamma-aminobutyric acid/benzodiazepine/beta-carboline receptor complex in rat spinal cord.
Journal of neurochemistry 1988;50(4):1080-6.
1988: A Roy; B Adinoff; L Roehrich; D Lamparski; R Custer; V Lorenz; M Barbaccia; Alessandro Guidotti; E Costa; Markku Linnoila
Pathological gambling. A psychobiological study.
Archives of general psychiatry 1988;45(4):369-73.
1988: M L Barbaccia; E Costa; Alessandro Guidotti
Endogenous ligands for high-affinity recognition sites of psychotropic drugs.
Annual review of pharmacology and toxicology 1988;28():451-76.
1988: Alessandro Guidotti; E Slobodyansky; A Berkovich; D H Cox; C Wambebe
The heterogeneity of GABAA receptors and the multiplicity of endogenous ligands for their allosteric modulatory centers.
Advances in biochemical psychopharmacology 1988;45():219-26.
1988: Erminio Costa; A Berkovich; C Wambebe; Alessandro Guidotti
Terminology for ligands of the allosteric modulatory center of GABA-operated Cl- channels.
Advances in biochemical psychopharmacology 1988;45():367-74.
1988: J Kardos; Alessandro Guidotti
Desensitization of GABA-stimulated 36Cl-influx in cerebellar granule cells.
Advances in biochemical psychopharmacology 1988;45():161-73.
1987: Flora M Vaccarino; Alessandro Guidotti; Erminio Costa
Ganglioside inhibition of glutamate-mediated protein kinase C translocation in primary cultures of cerebellar neurons.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(23):8707-11.
1987: M Fujimoto; Y Kataoka; Alessandro Guidotti; I Hanbauer
Effect of gamma-aminobutyric acidA receptor agonists and antagonists on the release of enkephalin-containing peptides from dog adrenal gland.
The Journal of pharmacology and experimental therapeutics 1987;243(1):195-9.
1987: E Costa; A Berkovich; Alessandro Guidotti
The regulation of GABAergic receptors by a novel family of endogenous neuropeptides.
Life sciences 1987;41(7):799-803.
1987: Carlo Ferrarese; Hannu Alho; Alessandro Guidotti; Erminio Costa
Co-localization and co-release of GABA and putative allosteric modulators of GABA receptor.
Neuropharmacology 1987;26(7B):1011-8.
1987: Carlo Ferrarese; Flora M Vaccarino; Hannu Alho; B Mellstrom; Erminio Costa; Alessandro Guidotti
Subcellular location and neuronal release of diazepam binding inhibitor.
Journal of neurochemistry 1987;48(4):1093-102.
1987: M Miyata; I Mocchetti; C Ferrarese; Alessandro Guidotti; Erminio Costa
Protracted treatment with diazepam increases the turnover of putative endogenous ligands for the benzodiazepine/beta-carboline recognition site.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(5):1444-8.
1987: Hannu Alho; M Miyata; E Korpi; K Kiianmaa; Alessandro Guidotti
Studies of a brain polypeptide functioning as a putative endogenous ligand to benzodiazepine recognition sites in rats selectively bred for alcohol related behavior.
Alcohol and alcoholism (Oxford, Oxfordshire). Supplement 1987;1():637-41.
1987: Flora M Vaccarino; H Alho; M R Santi; Alessandro Guidotti
Coexistence of GABA receptors and GABA-modulin in primary cultures of rat cerebellar granule cells.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1987;7(1):65-76.
1987: A Novelli; F Nicoletti; J T Wroblewski; H Alho; E Costa; Alessandro Guidotti
Excitatory amino acid receptors coupled with guanylate cyclase in primary cultures of cerebellar granule cells.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1987;7(1):40-7.
1986: P Ferrero; E Costa; B Conti-Tronconi; Alessandro Guidotti
A diazepam binding inhibitor (DBI)-like neuropeptide is detected in human brain.
Brain research 1986;399(1):136-42.
1986: M L Barbaccia; E Costa; P Ferrero; Alessandro Guidotti; A Roy; Trey Sunderland; DAVID PICKAR; S M Paul; F K Goodwin
Diazepam-binding inhibitor. A brain neuropeptide present in human spinal fluid: studies in depression, schizophrenia, and Alzheimer's disease.
Archives of general psychiatry 1986;43(12):1143-7.
1986: Y Kataoka; M Fujimoto; H Alho; Alessandro Guidotti; M Geffard; G D Kelly; I Hanbauer
Intrinsic gamma aminobutyric acid receptors modulate the release of catecholamine from canine adrenal gland in situ.
The Journal of pharmacology and experimental therapeutics 1986;239(2):584-90.
1986: P W Gray; D Glaister; P H Seeburg; Alessandro Guidotti; E Costa
Cloning and expression of cDNA for human diazepam binding inhibitor, a natural ligand of an allosteric regulatory site of the gamma-aminobutyric acid type A receptor.
Proceedings of the National Academy of Sciences of the United States of America 1986;83(19):7547-51.
1986: F Nicoletti; J T Wroblewski; A Novelli; Alessandro Guidotti; E Costa
Excitatory amino acid signal transduction in cerebellar cell cultures.
Functional neurology 1986;1(4):345-9.
1986: F Nicoletti; J T Wroblewski; A Novelli; H Alho; Alessandro Guidotti; E Costa
The activation of inositol phospholipid metabolism as a signal-transducing system for excitatory amino acids in primary cultures of cerebellar granule cells.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1986;6(7):1905-11.
1986: P Ferrero; M R Santi; B Conti-Tronconi; E Costa; Alessandro Guidotti
Study of an octadecaneuropeptide derived from diazepam binding inhibitor (DBI): biological activity and presence in rat brain.
Proceedings of the National Academy of Sciences of the United States of America 1986;83(3):827-31.
1986: P Ferrero; B Conti-Tronconi; Alessandro Guidotti
DBI, an anxiogenic neuropeptide found in human brain.
Advances in biochemical psychopharmacology 1986;41():177-85.
1986: Alessandro Guidotti; M R Santi; A Berkovich; Carlo Ferrarese; Erminio Costa
Structure-activity relationship of peptide fragments derived from DBI (diazepam binding inhibitor), a putative endogenous ligand of benzodiazepine recognition sites.
Clinical neuropharmacology 1986;9 Suppl 4():217-9.
1986: E Costa; H Alho; M R Santi; P Ferrero; Alessandro Guidotti
Cotransmission at GABAergic synapses.
Progress in brain research 1986;68():343-56.
1986: Alessandro Guidotti; I Hanbauer
Participation of GABA/benzodiazepine receptor system in the adrenal chromaffin cell function.
Advances in biochemical psychopharmacology 1986;42():165-72.
1986: Alessandro Guidotti; P Ferrero; M Fujimoto; R M Santi; E Costa
Studies on endogenous ligands (endacoids) for the benzodiazepine/beta carboline binding sites.
Advances in biochemical psychopharmacology 1986;41():137-48.
1985: I Mocchetti; Alessandro Guidotti; J P Schwartz; Erminio Costa
Reserpine changes the dynamic state of enkephalin stores in rat striatum and adrenal medulla by different mechanisms.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1985;5(12):3379-85.
1985: E Costa; Alessandro Guidotti
Endogenous ligands for benzodiazepine recognition sites.
Biochemical pharmacology 1985;34(19):3399-403.
1985: V Gallo; B C Wise; Flora M Vaccarino; Alessandro Guidotti
gamma-Aminobutyric acid- and benzodiazepine-induced modulation of [35S]-t-butylbicyclophosphorothionate binding to cerebellar granule cells.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1985;5(9):2432-8.
1985: H Alho; E Costa; P Ferrero; M Fujimoto; D Cosenza-Murphy; Alessandro Guidotti
Diazepam-binding inhibitor: a neuropeptide located in selected neuronal populations of rat brain.
Science (New York, N.Y.) 1985;229(4709):179-82.
1985: Charles Susanne; Alessandro Guidotti; Roland Hauspie
Age changes of skull dimensions.
Anthropologischer Anzeiger; Bericht über die biologisch-anthropologische Literatur 1985;43(1):31-6.
1985: Flora M Vaccarino; B M Tronconi; Pertti Panula; Alessandro Guidotti; E Costa
GABA-modulin: a synaptosomal basic protein that differs from small myelin basic protein of rat brain.
Journal of neurochemistry 1985;44(1):278-90.
1985: Alessandro Guidotti; P Ferrero; E Costa
On the brain endocoid for benzodiazepine recognition sites.
Progress in clinical and biological research 1985;192():477-84.
1985: J Bormann; P Ferrero; Alessandro Guidotti; E Costa
Neuropeptide modulation of GABA receptor C1- channels.
Regulatory peptides. Supplement 1985;4():33-8.
1985: Alessandro Guidotti; P Ferrero; M R Santi; H Alho; Stefano Vicini; E Costa
Gamma-aminobutyric acid and chloride channels: regulation by neuropeptides.
Regulatory peptides. Supplement 1985;4():172-81.
1984: P Ferrero; Alessandro Guidotti; B Conti-Tronconi; E Costa
A brain octadecaneuropeptide generated by tryptic digestion of DBI (diazepam binding inhibitor) functions as a proconflict ligand of benzodiazepine recognition sites.
Neuropharmacology 1984;23(11):1359-62.
1984: Tam Thanh Quach; F Tang; H Kageyama; I Mocchetti; Alessandro Guidotti; J L Meek; E Costa; J P Schwartz
Enkephalin biosynthesis in adrenal medulla. Modulation of proenkephalin mRNA content of cultured chromaffin cells by 8-bromo-adenosine 3',5'-monophosphate.
Molecular pharmacology 1984;26(2):255-60.
1984: E Costa; M Ferrari; P Ferrero; Alessandro Guidotti
Multiple signals in GABAergic transmission: pharmacological consequences.
Neuropharmacology 1984;23(8):989-91.
1984: M G Corda; M Ferrari; Alessandro Guidotti; D Konkel; E Costa
Isolation, purification and partial sequence of a neuropeptide (diazepam-binding inhibitor) precursor of an anxiogenic putative ligand for benzodiazepine recognition site.
Neuroscience letters 1984;47(3):319-24.
1984: Y Kataoka; Y Gutman; Alessandro Guidotti; Pertti Panula; J Wroblewski; D Cosenza-Murphy; J Y Wu; E Costa
Intrinsic GABAergic system of adrenal chromaffin cells.
Proceedings of the National Academy of Sciences of the United States of America 1984;81(10):3218-22.
1984: P Ferrero; Alessandro Guidotti; E Costa
Increase in the Bmax of gamma-aminobutyric acid-A recognition sites in brain regions of mice receiving diazepam.
Proceedings of the National Academy of Sciences of the United States of America 1984;81(7):2247-51.
1984: B C Wise; Alessandro Guidotti; E Costa
Regulation of the GABA receptor complex by a phosphorylation mechanism.
Advances in cyclic nucleotide and protein phosphorylation research 1984;17():511-9.
1984: H Kageyama; Alessandro Guidotti
Effect of alpha-bungarotoxin and etorphine on acetylcholine-evoked release of endogenous and radiolabeled catecholamines from primary culture of adrenal chromaffin cells.
Journal of neuroscience methods 1984;10(1):9-16.
1984: J P Schwartz; Tam Thanh Quach; F Tang; H Kageyama; Alessandro Guidotti; E Costa
Cyclic-AMP-mediated modulation of gene expression in adrenal chromaffin cell cultures.
Advances in cyclic nucleotide and protein phosphorylation research 1984;17():529-34.
1983: E Costa; M G Corda; Alessandro Guidotti
On a brain polypeptide functioning as a putative effector for the recognition sites of benzodiazepine and beta-carboline derivatives.
Neuropharmacology 1983;22(12B):1481-92.
1983: Alessandro Guidotti; M G Corda; B C Wise; Flora M Vaccarino; E Costa
GABAergic synapses. Supramolecular organization and biochemical regulation.
Neuropharmacology 1983;22(12B):1471-9.
1983: E Costa; Alessandro Guidotti; I Hanbauer; L Saiani
Modulation of nicotinic receptor function by opiate recognition sites highly selective for Met5-enkephalin[Arg6Phe7].
Federation proceedings 1983;42(12):2946-52.
1983: M G Corda; Alessandro Guidotti
Modulation of GABA receptor binding by Ca2+.
Journal of neurochemistry 1983;41(1):277-80.
1983: P Ferrero; Flora M Vaccarino; Alessandro Guidotti; E Costa; G Di Chiro
In vivo modulation of brain dopamine recognition sites: a possible model for emission computed tomography studies.
Neuropharmacology 1983;22(6):791-5.
1983: Alessandro Guidotti; C M Forchetti; M G Corda; D Konkel; C D Bennett; E Costa
Isolation, characterization, and purification to homogeneity of an endogenous polypeptide with agonistic action on benzodiazepine receptors.
Proceedings of the National Academy of Sciences of the United States of America 1983;80(11):3531-5.
1983: M G Corda; W D Blaker; W B Mendelson; Alessandro Guidotti; E Costa
beta-Carbolines enhance shock-induced suppression of drinking in rats.
Proceedings of the National Academy of Sciences of the United States of America 1983;80(7):2072-6.
1983: B C Wise; Alessandro Guidotti; E Costa
Phosphorylation induces a decrease in the biological activity of the protein inhibitor (GABA-modulin) of gamma-aminobutyric acid binding sites.
Proceedings of the National Academy of Sciences of the United States of America 1983;80(3):886-90.
1983: Alessandro Guidotti; M G Corda; E Costa
Strategies for the isolation and characterization of an endogenous effector of the benzodiazepine recognition sites.
Advances in biochemical psychopharmacology 1983;38():95-103.
1983: M G Corda; E Costa; Alessandro Guidotti
Involvement of GABA in the facilitation of punishment suppressed behavior induced by beta-carbolines in rat.
Advances in biochemical psychopharmacology 1983;38():121-7.
1983: Alessandro Guidotti; L Saiani; B C Wise; E Costa
Cotransmitters: pharmacological implications.
Journal of neural transmission. Supplementum 1983;18():213-25.
1982: Alessandro Guidotti; D R Konkel; B Ebstein; M G Corda; B C Wise; H Krutzsch; J L Meek; E Costa
Isolation, characterization, and purification to homogeneity of a rat brain protein (GABA-modulin).
Proceedings of the National Academy of Sciences of the United States of America 1982;79(19):6084-8.
1982: F Moroni; M C Forchetti; P Krogsgaard-Larsen; Alessandro Guidotti
Relative disposition of the GABA agonists THIP and muscimol in the brain of the rat.
The Journal of pharmacy and pharmacology 1982;34(10):676-8.
1982: L Grandison; F Cavagnini; R Schmid; S C Invitti; Alessandro Guidotti
gamma-Aminobutyric acid- and benzodiazepine-binding sites in human anterior pituitary tissue.
The Journal of clinical endocrinology and metabolism 1982;54(3):597-601.
1982: M G Corda; E Costa; Alessandro Guidotti
Specific proconvulsant action of an imidazobenzodiazepine (RO 15-1788) on isoniazid convulsions.
Neuropharmacology 1982;21(1):91-4.
1981: Menahem Segal; Alessandro Guidotti
Cyclic GMP in rat hippocampus: regulation by the septo-hippocampal pathway.
Neuropharmacology 1981;20(12A):1129-33.
1981: D S Shah; P Chambon; Alessandro Guidotti
Binding of (3H)-5,5 diphenylhydantoin to rat brain membranes.
Neuropharmacology 1981;20(11):1115-9.
1981: M Massotti; S Mazzari; R Schmid; Alessandro Guidotti; E Costa
Endogenous inhibitors of Na+-independent [3H]GABA binding to crude synaptic membranes.
Neurochemical research 1981;6(5):551-65.
1981: M Massotti; Alessandro Guidotti; E Costa
Characterization of benzodiazepine and gamma-aminobutyric recognition sites and their endogenous modulators.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1981;1(4):409-18.
1981: E Costa; Alessandro Guidotti; I Hanbauer; T Hexum; L Saiani; S Stine; H Y Yang
Regulation of acetylcholine receptors by endogenous cotransmitters: studies of adrenal medulla.
Federation proceedings 1981;40(2):160-5.
1981: M Massotti; Alessandro Guidotti; E Costa
The regulation of benzodiazepine recognition sites by endogenous modulators.
Advances in biochemical psychopharmacology 1981;26():19-26.
1981: S Mazzari; M Massotti; Alessandro Guidotti; E Costa
GABA receptors as supramolecular units.
Advances in biochemical psychopharmacology 1981;26():1-8.
1980: M Massotti; F R Alleva; T Balazs; Alessandro Guidotti
GABA and benzodiazepine receptors in the offspring of dams receiving diazepam: ontogenetic studies.
Neuropharmacology 1980;19(10):951-6.
1980: Alessandro Guidotti; M Baraldi; A Leon; E Costa
Benzodiazepines: a tool to explore the biochemical and neurophysiological basis of anxiety.
Federation proceedings 1980;39(12):3039-42.
1980: M Massotti; Alessandro Guidotti
Endogenous regulators of benzodiazepine recognition sites.
Life sciences 1980;27(10):847-54.
1980: A R Cananzi; E Costa; Alessandro Guidotti
Potentiation by intraventricular muscimol of the anticonflict effect of benzodiazepines.
Brain research 1980;196(2):447-53.
1980: E Bandle; Alessandro Guidotti
A simple and rapid method for the assay of cyclic GMP-dependent protein kinase.
Journal of neuroscience methods 1980;2(4):419-27.
1980: F Vargas; Alessandro Guidotti
Calmodulin in brain of schizophrenics.
Neurochemical research 1980;5(6):673-81.
1980: K Kumakura; F Karoum; Alessandro Guidotti; E Costa
Modulation of nicotinic receptors by opiate receptor agonists in cultured adrenal chromaffin cells.
Nature 1980;283(5746):489-92.
1980: K Kumakura; Alessandro Guidotti; H Y Yang; L Saiani; E Costa
A role for the opiate peptides that presumably coexist with acetylcholine in splanchnic nerves.
Advances in biochemical psychopharmacology 1980;22():571-80.
1980: Alessandro Guidotti
Pharmacological and biochemical evidence for an interaction between the benzodiazepine and GABA receptors.
Advances in biochemical psychopharmacology 1980;21():271-5.
1980: G Toffano; A Leon; M Massotti; Alessandro Guidotti; E Costa
GABA-modulin: a regulatory protein for GABA receptors.
Advances in biochemical psychopharmacology 1980;21():133-42.
1980: Alessandro Guidotti
Regulation of tyrosine hydroxylase after chronic treatment with classic and atypical antischizophrenic drugs.
Advances in biochemical psychopharmacology 1980;24():1-8.
1979: K Kumakura; Alessandro Guidotti; E Costa
Primary cultures of chromaffin cells: molecular mechanisms for the induction of tyrosine hydroxylase mediated by 8-Br-cyclic AMP.
Molecular pharmacology 1979;16(3):865-76.
1979: L Grandison; Alessandro Guidotti
gamma-Aminobutyric acid receptor function in rat anterior pituitary: evidence for control of prolactin release.
Endocrinology 1979;105(3):754-9.
1979: Alessandro Guidotti; K Gale; A Suria; G Toffano
Biochemical evidence for two classes of GABA receptors in rat brain.
Brain research 1979;172(3):566-71.
1979: M Baraldi; Alessandro Guidotti; J P Schwartz; E Costa
GABA receptors in clonal cell lines: a model for study of benzodiazepine action at molecular level.
Science (New York, N.Y.) 1979;205(4408):821-3.
1979: Alessandro Guidotti; M Baraldi; J P Schwartz; E Costa
Molecular mechanisms regulating the interactions between the benzodazepines and GABA receptors in the central nervous system.
Pharmacology, biochemistry, and behavior 1979;10(5):803-7.
1979: A Szmigielski; Alessandro Guidotti
Action of harmaline and diazepam on the cerebellar content of cyclic GMP and on the activities of two endogenous inhibitors of protein kinase.
Neurochemical research 1979;4(2):189-200.
1979: E Bandle; Alessandro Guidotti
Ontogenetic studies of cGMP-dependent protein kinase in rat cerebellum.
Journal of neurochemistry 1979;32(4):1343-7.
1979: K Gale; F Moroni; K Kumakura; Alessandro Guidotti
Opiate-receptors in substantia nigra: role in the regulation of striatal tyrosine hydroxylase activity.
Neuropharmacology 1979;18(4):427-30.
1979: Alessandro Guidotti; M Baraldi; E Costa
1,4-Benzodiazepines and gamma-aminobutyric acid: pharmacological and biochemical correlates.
Pharmacology 1979;19(5):267-77.
1979: M Baraldi; L Grandison; Alessandro Guidotti
Distribution and metabolism of muscimol in the brain and other tissues of the rat.
Neuropharmacology 1979;18(1):57-62.
1979: A Kurosawa; Alessandro Guidotti; E Costa
Nuclear translocation of cyclic AMP-dependent protein kinase subunits during the transsynaptic activation of gene expression in rat adrenal medulla.
Molecular pharmacology 1979;15(1):115-30.
1979: E Costa; Alessandro Guidotti
Recent studies on the mechanism whereby benzodiazepines facilitate GABA-ergic transmission.
Advances in experimental medicine and biology 1979;123():371-8.
1979: E Costa; Alessandro Guidotti
Molecular mechanisms in the receptor action of benzodiazepines.
Annual review of pharmacology and toxicology 1979;19():531-45.
1978: E Bandle; Alessandro Guidotti
Studies on the cell location of cyclic 3',5'-guanosine monophosphate-dependent protein kinase in cerebellum.
Brain research 1978;156(2):412-6.
1978: A Lucchelli; Alessandro Guidotti; E Costa
Stratial content of Ca2+-dependent regulator protein and dopaminergic receptor function.
Brain research 1978;155(1):130-5.
1978: Alessandro Guidotti; G Toffano; E Costa
An endogenous protein modulates the affinity of GABA and benzodiazepine receptors in rat brain.
Nature 1978;275(5680):553-5.
1978: E Costa; Alessandro Guidotti; G Toffano
Molecular mechanisms mediating the action of diazepam on GABA receptors.
The British journal of psychiatry : the journal of mental science 1978;133():239-48.
1978: Alessandro Guidotti; K Gale; G Toffano; F M Vargas
Tolerance to tyrosine hydroxylase activation in n. accumbens and c. striatum after repeated injections of "classical" and "atypical" antischizophrenic drugs.
Life sciences 1978;23(5):501-5.
1978: G Toffano; Alessandro Guidotti; E Costa
Purification of an endogenous protein inhibitor of the high affinity binding of gamma-aminobutyric acid to synaptic membranes of rat brain.
Proceedings of the National Academy of Sciences of the United States of America 1978;75(8):4024-8.
1978: K Gale; E Costa; G Toffano; J S Hong; Alessandro Guidotti
Evidence for a role of nigral gamma-aminobutyric acid and substance P in the haloperidol-induced activation of striatal tyrosine hydroxylase.
The Journal of pharmacology and experimental therapeutics 1978;206(1):29-37.
1978: Alessandro Guidotti; D M Chuang; R Hollenbeck; E Costa
Nuclear translocation of catalytic subunits of cytosol cAMP-dependent protein kinase in the transsynaptic induction of medullary tyrosine hydroxylase.
Advances in cyclic nucleotide research 1978;9():185-97.
1977: L Grandison; Alessandro Guidotti
Regulation of prolactin release by endogenous opiates.
Nature 1977;270(5635):357-9.
1977: G Biggio; B B Brodie; E Costa; Alessandro Guidotti
Mechanisms by which diazepam, muscimol, and other drugs change the content of cGMP in cerebellar cortex.
Proceedings of the National Academy of Sciences of the United States of America 1977;74(8):3592-6.
1977: L Grandison; Alessandro Guidotti
Stimulation of food intake by muscimol and beta endorphin.
Neuropharmacology 1977;16(7-8):533-6.
1977: A Szmigielski; Alessandro Guidotti; E Costa
Endogenous protein kinase inhibitors. Purification, characterization, and distribution in different tissues.
The Journal of biological chemistry 1977;252(11):3848-53.
1977: Alessandro Guidotti; E Costa
Commentary: Trans-synaptic regulation of typrosine 3-mono-oxygenase biosynthesis in rat adrenal medulla.
Biochemical pharmacology 1977;26(9):817-23.
1977: K Gale; Alessandro Guidotti; E Costa
Dopamine-sensitive adenylate cyclase: location in substantia nigra.
Science (New York, N.Y.) 1977;195(4277):503-5.
1977: G Biggio; D D Bella; V Frigeni; Alessandro Guidotti
Potentiation of morphine analgesia by muscimol.
Neuropharmacology 1977;16(2):149-50.
1977: G Biggio; Alessandro Guidotti
Regulation of cyclic GMP in cerebellum by a striatal dopaminergic mechanism.
Nature 1977;265(5591):240-2.
1977: G Biggio; E Costa; Alessandro Guidotti
Regulation of 3', 5'-cyclic guanosine monophosphate content in deep cerebellar nuclei.
Neuroscience 1977;2(1):49-52.
1977: Alessandro Guidotti; S R Naik; A Kurosawa
Possible role of gamma aminobutyric acid (GABA) in the regulation of cAMP system in rat anterior pituitary.
Psychoneuroendocrinology 1977;2(3):227-35.
1977: G Biggio; Alessandro Guidotti; E Costa
On the mechanism of the decrease in cerebellar cyclic GMP content elicited by opiate receptor agonists.
Naunyn-Schmiedeberg's archives of pharmacology 1977;296(2):117-21.
1977: Alessandro Guidotti; K Gale
Participation of GABA receptors in the short-term activation of striatal tyrosine-3-monooxygenase elicited by neuroleptics.
Advances in biochemical psychopharmacology 1977;16():455-60.
1977: G Biggio; E Costa; Alessandro Guidotti
Pharmacologically induced changes in the 3':5'-cyclic guanosine monophosphate content of rat cerebellar cortex: difference between apomorphine, haloperidol and harmaline.
The Journal of pharmacology and experimental therapeutics 1977;200(1):207-15.
1976: Alessandro Guidotti; A Kurosawa; E Costa
Association between the increase of cAMP content and the trans-synaptic induction of tyrosine hydroxylase in rat adrenal medulla. Studies with dexamethasone and reserpine.
Naunyn-Schmiedeberg's archives of pharmacology 1976;295(2):135-40.
1976: K N Gale; Alessandro Guidotti
GABA-mediated control of rat neostriatal tyrosine hydroxylase revealed by intranigral muscimol.
Nature 1976;263(5579):691-3.
1976: A Kurosawa; Alessandro Guidotti; E Costa
Induction of tyrosine 3-monooxygenase in adrenal medulla: role of protein kinase activation and translocation.
Science (New York, N.Y.) 1976;193(4254):691-3.
1976: S R Naik; Alessandro Guidotti; E Costa
Central GABA receptor agonists: comparison of muscimol and baclofen.
Neuropharmacology 1976;15(8):479-84.
1976: G Biggio; Alessandro Guidotti
Climbing fiver activation and 3', 5'-cyclic guanosine monophosphate (cGMP) content in cortex and deep nuclei of cerebellum.
Brain research 1976;107(2):365-73.
1976: A Kurosawa; Alessandro Guidotti; E Costa
Induction of tyrosine 3-monooxygenase elicited by carbamylcholine in intact and denervated adrenal medulla: role of protein kinase activation and translocation.
Molecular pharmacology 1976;12(3):420-32.
1976: E Costa; A Kurosawa; Alessandro Guidotti
Activation and nuclear translocation of protein kinase during transsynaptic induction of tyrosine 3-monooxygenase.
Proceedings of the National Academy of Sciences of the United States of America 1976;73(4):1058-62.
1976: G Racagni; G Zsilla; Alessandro Guidotti; E Costa
Accumulation of cGMP in striatum of rats injected with narcotic analgesics: antagonism by naltrexone.
The Journal of pharmacy and pharmacology 1976;28(3):258-60.
1976: G Biggio; E Costa; Alessandro Guidotti
Different mechanisms mediating the decrease of cerebellar cGMP elicited by haloperidol and diazepam.
Advances in biochemical psychopharmacology 1976;15():325-35.
1976: Alessandro Guidotti; A Kurosawa; E Costa
Role of histone kinase activation and translocation in the mediation of the transsynaptic induction of tyrosine hydroxylase in rat adrenal medulla.
Advances in biochemical psychopharmacology 1976;15():455-74.
1976: B Zivkovic; Alessandro Guidotti; E Costa
Cyclic AMP content and regulation of tyrosine-3-mono-oxygenase in rat striatum.
Journal of cyclic nucleotide research 1976;2(1):1-10.
1975: A Carenzi; D L Cheney; E Costa; Alessandro Guidotti; G Racagni
Action of opiates, antipsychotics, amphetamine and apomorphine on dopamine receptors in rat striatum: in vivo changes of 3',5'-cyclic AMP content and acetylcholine turnover rate.
Neuropharmacology 1975;14(12):927-39.
1975: I Hanbauer; W Lovenberg; Alessandro Guidotti; E Costa
Role of cholinergic and glucocorticosteroid receptors in the tyrosine hydroxylase induction elicited by reserpine in superior cervical ganglion.
Brain research 1975;96(1):197-200.
1975: Alessandro Guidotti; G Biggio; E Costa
3-Acetylpyridine: a tool to inhibit the tremor and the increase of cGMP content in cerebellar cortex elicited by harmaline.
Brain research 1975;96(1):201-5.
1975: E Costa; Alessandro Guidotti; C C Mao
Involvement of GABA in the action of benzodiazepine--studies on rat cerebellum.
Psychopharmacology bulletin 1975;11(4):59-60.
1975: A Carenzi; J C Gillin; Alessandro Guidotti; M A Schwartz; M Trabucchi; R J Wyatt
Dopamine-sensitive adenylyl cyclase in human caudate nucleus. A study in control subjects and schizophrenic patients.
Archives of general psychiatry 1975;32(8):1056-9.
1975: A Carenzi; Alessandro Guidotti; A Revuelta; E Costa
Molecular mechanisms in the actions of morphine and viminol (R2) on rat striatum.
The Journal of pharmacology and experimental therapeutics 1975;194(2):311-8.
1975: B Zivkovic; Alessandro Guidotti; E Costa
The regulation of the kinetic state of striatal tyrosine hydroxylase and the role of postsynaptic dopamine receptors.
Brain research 1975;92(3):516-21.
1975: E Costa; Alessandro Guidotti; C C Mao; A Suria
New concepts on the mechanism of action of benzodiazepines.
Life sciences 1975;17(2):167-85.
1975: B Zivkovic; Alessandro Guidotti; A Revuelta; E Costa
Effect of thioridazine, clozapine and other antipsychotics on the kinetic state of tyrosine hydroxylase and on the turnover rate of dopamine in striatum and nucleus accumbens.
The Journal of pharmacology and experimental therapeutics 1975;194(1):37-46.
1975: C C Mao; Alessandro Guidotti; S Landis
Cyclic GMP: reduction of cerebellar concentrations in "nervous" mutant mice.
Brain research 1975;90(2):335-9.
1975: B Zivkovic; Alessandro Guidotti; E Costa
Stereospecificity of dopamine receptors involved in the regulation of the kinetic state of tyrosine hydroxylase in striatum and nucleus accumbens.
The Journal of pharmacy and pharmacology 1975;27(5):359-60.
1975: I Hanbauer; I J Kopin; Alessandro Guidotti; E Costa
Induction of tyrosine hydroxylase elicited by beta adrenergic receptor agonists in normal and decentralized sympathetic ganglia: role of cyclic 3',5' - adenosine monophosphate.
The Journal of pharmacology and experimental therapeutics 1975;193(1):95-104.
1975: I Hanbauer; Alessandro Guidotti; E Costa
Dexamethasone induces tyrosine hydroxylase in sympathetic ganglia but not in adrenal medulla.
Brain research 1975;85(3):527-31.
1975: Alessandro Guidotti; A Kurosawa; D M Chuang; E Costa
Protein kinase activation as an early event in the trans-synaptic induction of tyrosine 3-monooxygenase in adrenal medulla.
Proceedings of the National Academy of Sciences of the United States of America 1975;72(3):1152-6.
1975: C C Mao; Alessandro Guidotti; E Costa
Inhibition by diazepam of the tremor and the increase of cerebellar cGMD content elicited by harmaline.
Brain research 1975;83(3):516-9.
1975: E Costa; Alessandro Guidotti; C C Mao
Evidence for involvement of GABA in the action of benzodiazepines: studies on rat cerebellum.
Advances in biochemical psychopharmacology 1975;(14):113-30.
1975: C C Mao; Alessandro Guidotti; E Costa
Evidence for an involvement of GABA in the mediation of the cerebellar cGMP decrease and the anticonvulsant action diazepam.
Naunyn-Schmiedeberg's archives of pharmacology 1975;289(4):369-78.
1975: Alessandro Guidotti; I Hanbauer; E Costa
Role of cyclic nucleotides in the induction of tyrosine hydroxylase.
Advances in cyclic nucleotide research 1975;5():619-39.
1975: B Zivkovic; Alessandro Guidotti; E Costa
The regulation of striatal tyrosine hydroxylase. Effects of gamma hydroxybutric acid and healperidol.
Naunyn-Schmiedeberg's archives of pharmacology 1975;291(2):193-200.
1974: Alessandro Guidotti; D L Cheney; M Trabucchi; M Doteuchi; C Wang
Focussed microwave radiation: a technique to minimize post mortem changes of cyclic nucleotides, dopa and choline and to preserve brain morphology.
Neuropharmacology 1974;13(12):1115-22.
1974: C C Mao; Alessandro Guidotti; E Costa
The regulation of cyclic guanosine monophosphate in rat cerebellum: possible involvement of putative amino acid neurotransmitters.
Brain research 1974;79(3):510-4.
1974: E Costa; Alessandro Guidotti; B Zivkovic
Proceedings: Short- and long-term regulation of tyrosine hydroxylase.
Psychopharmacology bulletin 1974;10(3):29-30.
1974: Alessandro Guidotti; E Costa
A role for nicotinic receptors in the regulation of the adenylate cyclase of adrenal medulla.
The Journal of pharmacology and experimental therapeutics 1974;189(3):665-75.
1974: E Costa; Alessandro Guidotti; I Hanbauer
Do cyclic nucleotides promote the trans-synaptic induction of tyrosine hydroxylase?
Life sciences 1974;14(7):1169-88.
1974: Alessandro Guidotti; C C Mao; E Costa
Delayed increase of tyrosine hydroxylase activity induced by transsynaptic stimulation in chromaffin cells: role of cyclic nucleotides as second messengers.
Advances in cytopharmacology 1974;2():39-46.
1974: E Costa; Alessandro Guidotti; B Zivkovic
Short- and long-term regulation of tyrosine hydroxylase.
Advances in biochemical psychopharmacology 1974;12(0):161-75.
1974: Alessandro Guidotti; E Costa
Association between increase in cyclic AMP and subsequent induction of tyrosine hydroxylase in rat adrenal medulla. Experiments with swimming stress.
Naunyn-Schmiedeberg's archives of pharmacology 1974;282(2):217-21.
1974: B Zivkovic; Alessandro Guidotti; E Costa
On the regulation of tryptophan hydroxylase in brain.
Advances in biochemical psychopharmacology 1974;11(0):19-30.
1973: B Zivkovic; Alessandro Guidotti; E Costa
Increase of tryptophan hydroxylase activity elicited by reserpine.
Brain research 1973;57(2):522-6.
1973: Alessandro Guidotti; E Costa
Involvement of adenosine 3',5'-monophosphate in the activation of tyrosine hydroxylase elicited by drugs.
Science (New York, N.Y.) 1973;179(4076):902-4.
1973: Alessandro Guidotti; B Zivkovic; R Pfeiffer; E Costa
Involvement of 3',5'-cyclic adenosine monophosphate in the increase of tyrosine hydroxylase activity elicited by cold exposure.
Naunyn-Schmiedeberg's archives of pharmacology 1973;278(2):195-206.
1972: Alessandro Guidotti; B Weiss; E Costa
Adenosine 3',5'-monophosphate concentrations and isoproterenol-induced synthesis of deoxyribonucleic acid in mouse parotid gland.
Molecular pharmacology 1972;8(5):521-30.
1972: Alessandro Guidotti; G Badiani; G Pepeu
Taurine distribution in cat brain.
Journal of neurochemistry 1972;19(2):431-5.