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Serafim Guimarães

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Manuela Morato; Dora Pinho; Teresa Sousa; Serafim Guimarães; Daniel Moura; António Albino-Teixeira
Pre- and postjunctional effects of angiotensin II in hypertension due to adenosine receptor blockade.
Serafim Guimarães; Helder José Marques Pinheiro
Functional evidence that in the cardiovascular system AT1 angiotensin II receptors are AT1B prejunctionally and AT1A postjunctionally.
Eduardo Moura; Paulo M Pinho Costa; Daniel Moura; Serafim Guimarães; Maria vieira-coelho
Decreased tyrosine hydroxylase activity in the adrenals of spontaneously hypertensive rats.

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2006: Manuela Morato; Dora Pinho; Teresa Sousa; Serafim Guimarães; Daniel Moura; António Albino-Teixeira
Pre- and postjunctional effects of angiotensin II in hypertension due to adenosine receptor blockade.
European journal of pharmacology 2006;531(1-3):209-16.
2005: Serafim Guimarães; Helder José Marques Pinheiro
Functional evidence that in the cardiovascular system AT1 angiotensin II receptors are AT1B prejunctionally and AT1A postjunctionally.
Cardiovascular research 2005;67(2):208-15.
2005: Eduardo Moura; Paulo M Pinho Costa; Daniel Moura; Serafim Guimarães; Maria vieira-coelho
Decreased tyrosine hydroxylase activity in the adrenals of spontaneously hypertensive rats.
Life sciences 2005;76(25):2953-64.
2004: Serafim Guimarães; Catarina Carneiro; Fernando Brandão; Helder José Marques Pinheiro; António Albino-Teixeira; Daniel Moura
A pharmacological differentiation between postjunctional (AT1A) and prejunctional (AT1B) angiotensin II receptors in the rabbit aorta.
Naunyn-Schmiedeberg's archives of pharmacology 2004;370(4):262-9.
2003: Alberto Mota; Serafim Guimarães
Influence of alpha2-autoreceptor stimulation on the facilitation by angiotensin II and bradykinin of noradrenaline release.
Naunyn-Schmiedeberg's archives of pharmacology 2003;368(6):443-7.
2003: Manuela Morato; Teresa Sousa; Serafim Guimarães; Daniel Moura; António Albino-Teixeira
Losartan and atenolol on hypertension induced by adenosine receptor blockade.
Autonomic & autacoid pharmacology 2003;23(2):133-40.
2003: Serafim Guimarães; Manuela Morato; Teresa Sousa; António Albino-Teixeira
Hypertension due to blockade of adenosine receptors.
Pharmacology & toxicology 2003;92(4):160-2.
2002: Helder José Marques Pinheiro; Daniel Moura; António Albino-Teixeira; C Alves; L Torres; Serafim Guimarães
A comparison of AT1 angiotensin II antagonists at pre- and postjunctional angiotensin II receptors of the rat tail artery.
Naunyn-Schmiedeberg's archives of pharmacology 2002;366(6):537-42.
2002: Manuela Morato; Teresa Sousa; Serafim Guimarães; Daniel Moura; António Albino-Teixeira
The role of angiotensin II in hypertension due to adenosine receptors blockade.
European journal of pharmacology 2002;455(2-3):135-41.
2002: Alberto Mota; Serafim Guimarães
Interaction between alpha2-autoreceptors and receptors mediating the effects of angiotensin II and bradykinin in the heart of newborn rats.
European journal of pharmacology 2002;453(2-3):265-70.
2001: Serafim Guimarães; Daniel Moura
Vascular adrenoceptors: an update.
Pharmacological reviews 2001;53(2):319-56.
2001: Serafim Guimarães; Helder José Marques Pinheiro; P Tavares; A Loio; Daniel Moura
Differential effects of eprosartan and losartan at prejunctional angiotensin II receptors.
Naunyn-Schmiedeberg's archives of pharmacology 2001;363(5):509-14.
2000: A Mota; MQ Paiva; Daniel Moura; Serafim Guimarães
Lack of interaction between alpha(2)-autoreceptors and prejunctional receptors mediating a facilitatory effect on noradrenaline release.
Pharmacological research : the official journal of the Italian Pharmacological Society 2000;42(4):383-7.
1999: Daniel Moura; Helder José Marques Pinheiro; MQ Paiva; Serafim Guimarães
Prejunctional effects of angiotensin II and bradykinin in the heart and blood vessels.
Journal of autonomic pharmacology 1999;19(6):321-5.
1999: MQ Paiva; Manuela Morato; Daniel Moura; Serafim Guimarães
A comparative study of postsynaptic alpha2-adrenoceptors of the dog mesenteric and rat femoral veins.
Naunyn-Schmiedeberg's archives of pharmacology 1999;360(2):165-70.
1999: Serafim Guimarães; Daniel Moura
Advances in vascular neuroeffector mechanisms.
Trends in pharmacological sciences 1999;20(3):90-3.
1999: J P Nunes; Serafim Guimarães
The influence of the wall tension on the contractile responses of arteries.
Fundamental & clinical pharmacology 1999;13(2):193-7.
1998: Serafim Guimarães; Isabel Pereira; Margarida Caramona; Daniel Moura; MQ Paiva
Prejunctional alpha2A-autoreceptors in the human gastric and ileocolic arteries.
Naunyn-Schmiedeberg's archives of pharmacology 1998;358(2):207-11.
1998: Serafim Guimarães; MQ Paiva; Daniel Moura
Different receptors for angiotensin II at pre- and postjunctional level of the canine mesenteric and pulmonary arteries.
British journal of pharmacology 1998;124(6):1207-12.
1998: Isabel Pereira; Margarida Caramona; MQ Paiva; Serafim Guimarães
The role of MAO-A and MAO-B in the metabolic degradation of noradrenaline in human arteries.
Journal of autonomic pharmacology 1998;18(2):123-8.
1998: Joao Tiago Guimaraes; MQ Paiva; Daniel Moura; Serafim Guimarães
Influence of maturation and ageing on the biotransformation of noradrenaline in the rat.
Journal of neural transmission. Supplementum 1998;52():225-32.
1997: Serafim Guimarães; MQ Paiva; O Pereira
Alpha-adrenoceptor-mediated prejunctional effects of chloroethylclonidine in the canine saphenous vein.
The Journal of pharmacology and experimental therapeutics 1997;282(3):1326-30.
1997: MQ Paiva; A Mota; Daniel Moura; Serafim Guimarães
Prejunctional alpha2A-autoreceptors in the canine saphenous vein.
Naunyn-Schmiedeberg's archives of pharmacology 1997;356(3):368-73.
1996: Serafim Guimarães; A Albino-Teixeira
Hypertension due to chronic blockade of P1-purinoceptors.
Journal of autonomic pharmacology 1996;16(6):367-70.
1996: F Brandão; MQ Paiva; A Albino-Teixeira; P Serrão; Serafim Guimarães
Homogeneous or heterogeneous distribution of systemically administered adrenaline: organ dependence.
Naunyn-Schmiedeberg's archives of pharmacology 1996;353(5):579-83.
1996: MQ Paiva; M J Santos; Serafim Guimarães
Pre- and postjunctional effects of 5-hydroxytryptamine in dog cephalic veins of neonates.
General pharmacology 1996;27(2):325-8.
1995: M J Vaz-da-Silva; Serafim Guimarães; Daniel Moura
Adenosine and the endothelium-dependent modulation of 3H-noradrenaline release in the canine pulmonary artery.
Naunyn-Schmiedeberg's archives of pharmacology 1995;352(6):640-5.
1995: R Begonha; Daniel Moura; Serafim Guimarães
Vascular beta-adrenoceptor-mediated relaxation and the tone of the tissue in canine arteries.
The Journal of pharmacy and pharmacology 1995;47(6):510-3.
1995: Serafim Guimarães; A Albino-Teixeira; MQ Paiva
Hypertension and enhanced beta-adrenoceptor-mediated facilitation of noradrenaline release produced by chronic blockade of adenosine receptors.
British journal of pharmacology 1995;114(8):1595-8.
1994: Serafim Guimarães; MQ Paiva; Daniel Moura; M J Vaz-da-Silva; A Albino-Teixeira
Long-term administration of 1,3-dipropyl-8-sulphophenylxanthine (DPSPX) alters alpha 2-adrenoceptor-mediated effects at the pre- but not at the postjunctional level.
Naunyn-Schmiedeberg's archives of pharmacology 1994;350(6):692-5.
1994: MQ Paiva; Daniel Moura; M J Vaz-da-Silva; Serafim Guimarães
Postnatal development of vascular beta-adrenoceptor-mediated responses and the increase in the adrenaline content of the adrenal gland have a parallel time course.
Naunyn-Schmiedeberg's archives of pharmacology 1994;350(1):28-33.
1994: Serafim Guimarães; Daniel Moura; MQ Paiva; M J Vaz-da-Silva
Lack of pre- and postjunctional beta adrenoceptor-mediated effects in the canine saphenous vein at birth.
The Journal of pharmacology and experimental therapeutics 1994;268(2):990-5.
1993: J P Nunes; Serafim Guimarães
Chloroethylclonidine irreversibly activates postjunctional alpha 2-adrenoceptors in the dog saphenous vein.
Naunyn-Schmiedeberg's archives of pharmacology 1993;348(3):264-8.
1993: Serafim Guimarães; A Mota; R Begonha
The effectiveness of beta-adrenoceptor stimulation and the contribution of beta 1-adrenoceptors increase from the proximal to the distal part of the canine saphenous vein.
Naunyn-Schmiedeberg's archives of pharmacology 1993;347(6):596-600.
1993: Daniel Moura; M J Vaz-da-Silva; Isabel Azevedo; F Brandão; Serafim Guimarães
Release and disposition of 3H-noradrenaline in the saphenous vein of neonate and adult dogs.
Naunyn-Schmiedeberg's archives of pharmacology 1993;347(2):186-91.
1992: J Proença; Serafim Guimarães
Influence of inhibition of extraneuronal uptake and of O-methylation on the hyperglycaemia caused by sympathomimetic amines in depancreatized rats.
The Journal of pharmacy and pharmacology 1992;44(2):139-41.
1991: J Gonçalves; Serafim Guimarães
Influence of neuronal uptake on pre- and postjunctional effects of alpha-adrenoceptor agonists in tissues with noradrenaline--ATP cotransmission.
Naunyn-Schmiedeberg's archives of pharmacology 1991;344(5):532-7.
1991: O Pereira; Daniel Moura; P Nunes; M J Vaz-da Silva; Serafim Guimarães
Involvement of alpha 1- and alpha 2-adrenoceptors in the responses of proximal and distal segments of the canine saphenous vein to exogenous and endogenous noradrenaline.
Naunyn-Schmiedeberg's archives of pharmacology 1991;343(6):616-22.
1991: J P Nunes; Daniel Moura; Serafim Guimarães; I S de la Lande
Postsynaptic alpha-adrenoceptors in the perfused canine saphenous vein in vitro.
Pharmacological research : the official journal of the Italian Pharmacological Society 1991;23(4):409-14.
1991: Serafim Guimarães; Daniel Moura; J P Nunes; M J Vaz-da-Silva; Joao Tiago Guimaraes
Alpha 1- and alpha 2-adrenoceptors at different levels of the canine saphenous vein.
Journal of neural transmission. Supplementum 1991;34():163-9.
1990: Daniel Moura; Isabel Azevedo; Serafim Guimarães
Differential distribution in, and release from, sympathetic nerve endings of endogenous noradrenaline and recently incorporated catecholamines.
Naunyn-Schmiedeberg's archives of pharmacology 1990;342(2):153-9.
1990: Daniel Moura; M J Vaz-da-Silva; Serafim Guimarães
Alpha-adrenoceptor reserve in the canine cephalic vein.
European journal of pharmacology 1990;179(1-2):9-16.
1990: J Proença; MQ Paiva; Serafim Guimarães
Supersensitivity to catecholamines after inhibition of extraneuronal uptake (uptake2) or O-methylation.
Journal of neural transmission. Supplementum 1990;32():463-7.
1989: J Gonçalves; Félix Carvalho; Serafim Guimarães
Uptake inhibitors do not change the effect of imidazoline alpha 2-adrenoceptor agonists on transmitter release evoked by single pulse stimulation in mouse vas deferens.
Naunyn-Schmiedeberg's archives of pharmacology 1989;339(3):288-92.
1988: J Gonçalves; J P Nunes; MQ Paiva; Serafim Guimarães
Loss of selectivity of so-called selective alpha 1-adrenoceptor agonists after phenoxybenzamine.
Naunyn-Schmiedeberg's archives of pharmacology 1988;338(3):234-8.
1988: J Proença; MQ Paiva; Serafim Guimarães
The guinea-pig trachea O-methylating system is more effective in modulating beta 2- than beta 1-adrenoceptor-mediated responses to isoprenaline.
The Journal of pharmacy and pharmacology 1988;40(1):76-7.
1987: Serafim Guimarães; MQ Paiva
Postsynaptic alpha-adrenoceptor reserve and the shift of the concentration-response curves to the right, as caused by the irreversible alpha-adrenoceptor antagonist phenoxybenzamine.
British journal of pharmacology 1987;92(3):505-12.
1987: J P Nunes; M J Vaz-Da-Silva; F Brandão; Serafim Guimarães
An unusually important role of O-methylation in the disposition of noradrenaline and adrenaline by the dog renal artery.
Archives internationales de pharmacodynamie et de thérapie 1987;289(2):189-97.
1987: Serafim Guimarães; MQ Paiva; Daniel Moura
Alpha 2-adrenoceptor-mediated responses to so-called selective alpha 1-adrenoceptor agonists after partial blockade of alpha 1-adrenoceptors.
Naunyn-Schmiedeberg's archives of pharmacology 1987;335(4):397-402.
1985: Serafim Guimarães; MQ Paiva; Daniel Moura; J Proença
The saturability of a site of loss and the degree of supersensitivity to agonists which are substrates of this site of loss.
Naunyn-Schmiedeberg's archives of pharmacology 1985;329(1):30-5.
1985: J J Polónia; MQ Paiva; Serafim Guimarães
Pharmacological characterization of postsynaptic alpha-adrenoceptor subtypes in five different dog arteries in-vitro.
The Journal of pharmacy and pharmacology 1985;37(3):205-8.
1984: MQ Paiva; Serafim Guimarães
The kinetic characteristics of the extraneuronal Q-methylating system of the dog saphenous vein and the supersensitivity to catecholamines caused by its inhibition.
Naunyn-Schmiedeberg's archives of pharmacology 1984;327(1):48-55.
1982: Serafim Guimarães; MQ Paiva; Daniel Moura
Evidence for the existence of distinct biophases for alpha- and beta-adrenoceptors in the vascular tissue.
Journal of cardiovascular pharmacology 1982;4 Suppl 1():S58-62.
1981: Serafim Guimarães; MQ Paiva
Two different biophases for adrenaline released by electrical stimulation or tyramine from the sympathetic nerve endings of the dog saphenous vein.
Naunyn-Schmiedeberg's archives of pharmacology 1981;316(3):200-4.
1981: Serafim Guimarães; MQ Paiva
Two distinct adrenoceptor-biophases in the vasculature: one for alpha- and the other for beta-agonists.
Naunyn-Schmiedeberg's archives of pharmacology 1981;316(3):195-9.
1980: MQ Paiva; Serafim Guimarães
The oil immersion technique for studying the disposition of drugs inducing relaxation; influence of U-0521 and hydrocortisone on the disposition of isoprenaline.
The Journal of pharmacy and pharmacology 1980;32(12):868-9.
1980: F Brandão; MQ Paiva; Serafim Guimarães
The role of neuronal and extraneuronal systems in the metabolism of adrenaline and noradrenaline released from nerve terminals by electrical stimulation.
Naunyn-Schmiedeberg's archives of pharmacology 1980;311(1):1-7.