Erich Gulbins

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Dumitru Claudia Alexandra; Weller Michael; Gulbins Erich
Ceramide metabolism determines glioma cell resistance to chemotherapy.
Kornhuber Johannes; Reichel Martin; Tripal Philipp; Groemer Teja W; Henkel Andreas W; Mühle Christiane; Gulbins Erich
The role of ceramide in major depressive disorder.
Gassert Evelyn; Avota Elita; Harms Harry; Krohne Georg; Gulbins Erich; Schneider-Schaulies Sibylle
Induction of membrane ceramides: a novel strategy to interfere with T lymphocyte cytoskeletal reorganisation in viral immunosuppression.

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All Publications

2009: Dumitru Claudia Alexandra; Weller Michael; Gulbins Erich
Ceramide metabolism determines glioma cell resistance to chemotherapy.
Journal of cellular physiology 2009;221(3):688-95.
2009: Kornhuber Johannes; Reichel Martin; Tripal Philipp; Groemer Teja W; Henkel Andreas W; Mühle Christiane; Gulbins Erich
The role of ceramide in major depressive disorder.
European archives of psychiatry and clinical neuroscience 2009;259 Suppl 2():S199-204.
2009: Gassert Evelyn; Avota Elita; Harms Harry; Krohne Georg; Gulbins Erich; Schneider-Schaulies Sibylle
Induction of membrane ceramides: a novel strategy to interfere with T lymphocyte cytoskeletal reorganisation in viral immunosuppression.
PLoS pathogens 2009;5(10):e1000623.
2009: Braun Manuel; Föller Michael; Gulbins Erich; Lang Florian
Eryptosis triggered by bismuth.
Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine 2009;22(3):453-60.
2009: Zoratti Mario; De Marchi Umberto; Gulbins Erich; Szabò Ildikò
Novel channels of the inner mitochondrial membrane.
Biochimica et biophysica acta 2009;1787(5):351-63.
2009: Döring Gerd; Gulbins Erich
Cystic fibrosis and innate immunity: how chloride channel mutations provoke lung disease.
Cellular microbiology 2009;11(2):208-16.
2009: Schenck M; Rübben H; Gulbins E
[Molecular aspects of lymph node metastasis]
Der Urologe. Ausg. A 2009;48(1):6-11.
2009: Zhang Yang; Li Xiang; Becker Katrin Anne; Gulbins Erich
Ceramide-enriched membrane domains--structure and function.
Biochimica et biophysica acta 2009;1788(1):178-83.
2009: Lang Philipp A; Kasinathan Ravi S; Brand Verena B; Duranton Christophe; Lang Camelia; Koka Saisudha; Shumilina Ekaterina; Kempe Daniela S; Tanneur Valerie; Akel Ahmad; Lang Karl S; Foller Michael; Kun Jurgen F J; Kremsner Peter G; Wesselborg Sebastian; Laufer Stefan; Clemen Christoph S; Herr Claudia; Noegel Angelika A; Wieder Thomas; Gulbins Erich; Lang Florian; Huber Stephan M
Accelerated clearance of Plasmodium-infected erythrocytes in sickle cell trait and annexin-A7 deficiency.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2009;24(5-6):415-28.
2009: Föller Michael; Bobbala Diwakar; Koka Saisudha; Huber Stephan M; Gulbins Erich; Lang Florian
Suicide for survival--death of infected erythrocytes as a host mechanism to survive malaria.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2009;24(3-4):133-40.
2009: Riethmüller Joachim; Anthonysamy Janina; Serra Emilio; Schwab Matthias; Döring Gerd; Gulbins Erich
Therapeutic efficacy and safety of amitriptyline in patients with cystic fibrosis.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2009;24(1-2):65-72.
2008: Uhlig Stefan; Gulbins Erich
Sphingolipids in the lungs.
American journal of respiratory and critical care medicine 2008;178(11):1100-14.
2008: Gulbins Erich
Highlight: sphingolipids - signals and disease.
Biological chemistry 2008;389(11):1347-8.
2008: Grassmé Heike; Becker Katrin Anne; Zhang Yang; Gulbins Erich
Ceramide in bacterial infections and cystic fibrosis.
Biological chemistry 2008;389(11):1371-9.
2008: Szabó Ildikò; Bock Jürgen; Grassmé Heike; Soddemann Matthias; Wilker Barbara; Lang Florian; Zoratti Mario; Gulbins Erich
Mitochondrial potassium channel Kv1.3 mediates Bax-induced apoptosis in lymphocytes.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(39):14861-6.
2008: Zhang Yang; Li Xiang; Carpinteiro Alexander; Gulbins Erich
Acid sphingomyelinase amplifies redox signaling in Pseudomonas aeruginosa-induced macrophage apoptosis.
Journal of immunology (Baltimore, Md. : 1950) 2008;181(6):4247-54.
2008: Carpinteiro Alexander; Dumitru Claudia; Schenck Marcus; Gulbins Erich
Ceramide-induced cell death in malignant cells.
Cancer letters 2008;264(1):1-10.
2008: Teichgräber Volker; Ulrich Martina; Endlich Nicole; Riethmüller Joachim; Wilker Barbara; De Oliveira-Munding Cheyla Conceição; van Heeckeren Anna M; Barr Mark L; von Kürthy Gabriele; Schmid Kurt W; Weller Michael; Tümmler Burkhard; Lang Florian; Grassme Heike; Döring Gerd; Gulbins Erich
Ceramide accumulation mediates inflammation, cell death and infection susceptibility in cystic fibrosis.
Nature medicine 2008;14(4):382-91.
2008: Riethmueller Joachim; Vonthein Reinhard; Borth-Bruhns Thomas; Grassmé Heike; Eyrich Matthias; Schilbach Karin; Stern Martin; Gulbins Erich
DNA quantification and fragmentation in sputum after inhalation of recombinant human deoxyribonuclease.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2008;22(1-4):347-52.
2008: Becker Katrin Anne; Gellhaus Alexandra; Winterhager Elke; Gulbins Erich
Ceramide-enriched membrane domains in infectious biology and development.
Sub-cellular biochemistry 2008;49():523-38.
2008: Möröy Tarik; Zeng Hui; Jin Jianmin; Schmid Kurt Werner; Carpinteiro Alexander; Gulbins Erich
The zinc finger protein and transcriptional repressor Gfi1 as a regulator of the innate immune response.
Immunobiology 2008;213(3-4):341-52.
2007: Dumitru Claudia Alexandra; Zhang Yang; Li Xiang; Gulbins Erich
Ceramide: a novel player in reactive oxygen species-induced signaling?
Antioxidants & redox signaling 2007;9(9):1535-40.
2007: Schenck M; Boergermann C; vom Dorp F; Busch Y; Groneberg M; Wilker B; Keitsch S; Moyrer S; Schmid K W; Stuschke M; Ruebben H; Gulbins E
[Identification of the molecular bases of metastasis for the development of new therapy strategies of metastatic prostate carcinoma]
Der Urologe. Ausg. A 2007;46(9):1261-2.
2007: Schenck M; vom Dorp F; Boergermann C; Busch Y; Carpinteiro A; Wilker B; Keitsch S; Schmid K W; Groneberg M; Stuschke M; Ruebben H; Gulbins E
[Founding a "Lymph Node Metastasis" Study Group at the West German Tumor Center (WTZE)]
Der Urologe. Ausg. A 2007;46(9):1257-60.
2007: Schenck M; Börgermann C; vom Dorp F; Groneberg M; Busch Y; Carpinteiro A; Wilker B; Keitsch S; Moyrer S; Schmid K W; Stuschke M; Rübben H; Gulbins E
[Proapoptotic antibodies as new therapeutic agents for tumor treatment]
Der Urologe. Ausg. A 2007;46(9):1262-5.
2007: Grammatikos Georgios; Teichgräber Volker; Carpinteiro Alexander; Trarbach Tanja; Weller Michael; Hengge Ulrich R; Gulbins Erich
Overexpression of acid sphingomyelinase sensitizes glioma cells to chemotherapy.
Antioxidants & redox signaling 2007;9(9):1449-56.
2007: Dumitru Claudia Alexandra; Carpinteiro Alexander; Trarbach Tanja; Hengge Ulrich R; Gulbins Erich
Doxorubicin enhances TRAIL-induced cell death via ceramide-enriched membrane platforms.
Apoptosis : an international journal on programmed cell death 2007;12(8):1533-41.
2007: Schenck Marcus; Carpinteiro Alexander; Grassmé Heike; Lang Florian; Gulbins Erich
Ceramide: physiological and pathophysiological aspects.
Archives of biochemistry and biophysics 2007;462(2):171-5.
2007: Lang Florian; Huber Stephan M; Szabo Ildiko; Gulbins Erich
Plasma membrane ion channels in suicidal cell death.
Archives of biochemistry and biophysics 2007;462(2):189-94.
2007: Grassmé Heike; Riethmüller Joachim; Gulbins Erich
Biological aspects of ceramide-enriched membrane domains.
Progress in lipid research 2007;46(3-4):161-70.
2007: Kempe Daniela S; Akel Ahmad; Lang Philipp A; Hermle Tobias; Biswas Raja; Muresanu Juliana; Friedrich Björn; Dreischer Peter; Wolz Christiane; Schumacher Ulrike; Peschel Andreas; Götz Friedrich; Döring Gerd; Wieder Thomas; Gulbins Erich; Lang Florian
Suicidal erythrocyte death in sepsis.
Journal of molecular medicine (Berlin, Germany) 2007;85(3):273-81.
2007: Lang Philipp A; Schenck Marcus; Nicolay Jan P; Becker Jan Ulrich; Kempe Daniela S; Lupescu Adrian; Koka Saisudha; Eisele Kerstin; Klarl Barbara A; Rübben Herbert; Schmid Kurt W; Mann Klaus; Hildenbrand Sibylle; Hefter Harald; Huber Stephan M; Wieder Thomas; Erhardt Andreas; Häussinger Dieter; Gulbins Erich; Lang Florian
Liver cell death and anemia in Wilson disease involve acid sphingomyelinase and ceramide.
Nature medicine 2007;13(2):164-70.
2007: Dreschers S; Dumitru C A; Adams C; Gulbins E
The cold case: are rhinoviruses perfectly adapted pathogens?
Cellular and molecular life sciences : CMLS 2007;64(2):181-91.
2007: Lang Florian; Föller Michael; Lang Karl; Lang Philipp; Ritter Markus; Vereninov Alexey; Szabo Ildiko; Huber Stephan M; Gulbins Erich
Cell volume regulatory ion channels in cell proliferation and cell death.
Methods in enzymology 2007;428():209-25.
2007: Dreschers Stephan; Franz Peter; Dumitru Claudia; Wilker Barbara; Jahnke Klaus; Gulbins Erich
Infections with human rhinovirus induce the formation of distinct functional membrane domains.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2007;20(1-4):241-54.
2007: Nicolay Jan P; Gatz Sabine; Liebig Gerd; Gulbins Erich; Lang Florian
Amyloid induced suicidal erythrocyte death.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2007;19(1-4):175-84.
2006: Riethmüller Joachim; Riehle Andrea; Grassmé Heike; Gulbins Erich
Membrane rafts in host-pathogen interactions.
Biochimica et biophysica acta 2006;1758(12):2139-47.
2006: Dumitru C A; Gulbins E
TRAIL activates acid sphingomyelinase via a redox mechanism and releases ceramide to trigger apoptosis.
Oncogene 2006;25(41):5612-25.
2006: Grassmé Heike; Jin Jianmin; Wilker Barbara; von Kürthy Gabriele; Wick Wolfgang; Weller Michael; Möröy Tarik; Gulbins Erich
Regulation of pulmonary Pseudomonas aeruginosa infection by the transcriptional repressor Gfi1.
Cellular microbiology 2006;8(7):1096-105.
2006: Kirschnek Susanne; Gulbins Erich
Phospholipase A2 functions in Pseudomonas aeruginosa-induced apoptosis.
Infection and immunity 2006;74(2):850-60.
2006: Gulbins Erich; Li Pin Lan
Physiological and pathophysiological aspects of ceramide.
American journal of physiology. Regulatory, integrative and comparative physiology 2006;290(1):R11-26.
2006: Lang Florian; Shumilina Ekaterina; Ritter Markus; Gulbins Erich; Vereninov Alexey; Huber Stephan M
Ion channels and cell volume in regulation of cell proliferation and apoptotic cell death.
Contributions to nephrology 2006;152():142-60.
2006: Lang Philipp A; Huober Jens; Bachmann Cornelia; Kempe Daniela S; Sobiesiak Malgorzata; Akel Ahmad; Niemoeller Olivier M; Dreischer Peter; Eisele Kerstin; Klarl Barbara A; Gulbins Erich; Lang Florian; Wieder Thomas
Stimulation of erythrocyte phosphatidylserine exposure by paclitaxel.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2006;18(1-3):151-64.
2006: Dumitru Claudia Alexandra; Dreschers Stephan; Gulbins Erich
Rhinoviral infections activate p38MAP-kinases via membrane rafts and RhoA.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2006;17(3-4):159-66.
2005: Bollinger Claudia R; Teichgräber Volker; Gulbins Erich
Ceramide-enriched membrane domains.
Biochimica et biophysica acta 2005;1746(3):284-94.
2005: Grassmé Heike; Riehle Andrea; Wilker Barbara; Gulbins Erich
Rhinoviruses infect human epithelial cells via ceramide-enriched membrane platforms.
The Journal of biological chemistry 2005;280(28):26256-62.
2005: Lang F; Föller M; Lang K S; Lang P A; Ritter M; Gulbins E; Vereninov A; Huber S M
Ion channels in cell proliferation and apoptotic cell death.
The Journal of membrane biology 2005;205(3):147-57.
2005: Szabò Ildikò; Bock Jurgen; Jekle Andreas; Soddemann Matthias; Adams Constantin; Lang Florian; Zoratti Mario; Gulbins Erich
A novel potassium channel in lymphocyte mitochondria.
The Journal of biological chemistry 2005;280(13):12790-8.
2005: Kirschnek Susanne; Adams Constantin; Gulbins Erich
Annexin II is a novel receptor for Pseudomonas aeruginosa.
Biochemical and biophysical research communications 2005;327(3):900-6.
2004: Lang Florian; Gulbins Erich; Szabo Ildiko; Lepple-Wienhues Albrecht; Huber Stephan M; Duranton Christophe; Lang Karl S; Lang Philipp A; Wieder Thomas
Cell volume and the regulation of apoptotic cell death.
Journal of molecular recognition : JMR 2004;17(5):473-80.
2004: Szabò I; Adams C; Gulbins E
Ion channels and membrane rafts in apoptosis.
Pflügers Archiv : European journal of physiology 2004;448(3):304-12.
2004: Gulbins Erich; Dreschers Stephan; Wilker Barbara; Grassmé Heike
Ceramide, membrane rafts and infections.
Journal of molecular medicine (Berlin, Germany) 2004;82(6):357-63.
2003: Gulbins Erich; Kolesnick Richard
Raft ceramide in molecular medicine.
Oncogene 2003;22(45):7070-7.
2003: Grassmé Heike; Cremesti Aida; Kolesnick Richard; Gulbins Erich
Ceramide-mediated clustering is required for CD95-DISC formation.
Oncogene 2003;22(35):5457-70.
2003: Fanzo Jessica C; Lynch Maureen P; Phee Hyewon; Hyer Marc; Cremesti Aida; Grassme Heike; Norris James S; Coggeshall K Mark; Rueda Bo R; Pernis Alessandra B; Kolesnick Richard; Gulbins Erich
CD95 rapidly clusters in cells of diverse origins.
Cancer biology & therapy 2003;2(4):392-5.
2003: Bock Jürgen; Szabó Ildikò; Gamper Nikita; Adams Constantin; Gulbins Erich
Ceramide inhibits the potassium channel Kv1.3 by the formation of membrane platforms.
Biochemical and biophysical research communications 2003;305(4):890-7.
2003: Gulbins Erich
Regulation of death receptor signaling and apoptosis by ceramide.
Pharmacological research : the official journal of the Italian Pharmacological Society 2003;47(5):393-9.
2003: Grassmé H; Jendrossek V; Riehle A; von Kürthy G; Berger J; Schwarz H; Weller M; Kolesnick R; Gulbins E
Host defense against Pseudomonas aeruginosa requires ceramide-rich membrane rafts.
Nature medicine 2003;9(3):322-30.
2003: Gulbins Erich; Dreschers Stephan; Bock Jürgen
Role of mitochondria in apoptosis.
Experimental physiology 2003;88(1):85-90.
2002: Gulbins Erich; Grassmé Heike
Ceramide and cell death receptor clustering.
Biochimica et biophysica acta 2002;1585(2-3):139-45.
2002: Grassmé Heike; Bock Jürgen; Kun Jutta; Gulbins Erich
Clustering of CD40 ligand is required to form a functional contact with CD40.
The Journal of biological chemistry 2002;277(33):30289-99.
2002: Bock Jürgen; Szabó Ildikò; Jekle Andreas; Gulbins Erich
Actinomycin D-induced apoptosis involves the potassium channel Kv1.3.
Biochemical and biophysical research communications 2002;295(2):526-31.
2002: Grassmé Heike; Jendrossek Verena; Bock Jürgen; Riehle Andrea; Gulbins Erich
Ceramide-rich membrane rafts mediate CD40 clustering.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(1):298-307.
2002: Gulbins Erich; Kolesnick Richard
Acid sphingomyelinase-derived ceramide signaling in apoptosis.
Sub-cellular biochemistry 2002;36():229-44.
2001: Grassmé H; Jendrossek V; Gulbins E
Molecular mechanisms of bacteria induced apoptosis.
Apoptosis : an international journal on programmed cell death 2001;6(6):441-5.
2001: Esen M; Schreiner B; Jendrossek V; Lang F; Fassbender K; Grassmé H; Gulbins E
Mechanisms of Staphylococcus aureus induced apoptosis of human endothelial cells.
Apoptosis : an international journal on programmed cell death 2001;6(6):431-9.
2001: Röhn T A; Wagenknecht B; Roth W; Naumann U; Gulbins E; Krammer P H; Walczak H; Weller M
CCNU-dependent potentiation of TRAIL/Apo2L-induced apoptosis in human glioma cells is p53-independent but may involve enhanced cytochrome c release.
Oncogene 2001;20(31):4128-37.
2001: Wagenknecht B; Roth W; Gulbins E; Wolburg H; Weller M
C2-ceramide signaling in glioma cells: synergistic enhancement of CD95-mediated, caspase-dependent apoptosis.
Cell death and differentiation 2001;8(6):595-602.
2001: Grassmé H; Schwarz H; Gulbins E
Molecular mechanisms of ceramide-mediated CD95 clustering.
Biochemical and biophysical research communications 2001;284(4):1016-30.
2001: Cremesti A; Paris F; Grassmé H; Holler N; Tschopp J; Fuks Z; Gulbins E; Kolesnick R
Ceramide enables fas to cap and kill.
The Journal of biological chemistry 2001;276(26):23954-61.
2001: Grassme H; Jekle A; Riehle A; Schwarz H; Berger J; Sandhoff K; Kolesnick R; Gulbins E
CD95 signaling via ceramide-rich membrane rafts.
The Journal of biological chemistry 2001;276(23):20589-96.
2001: Jendrossek V; Grassmé H; Mueller I; Lang F; Gulbins E
Pseudomonas aeruginosa-induced apoptosis involves mitochondria and stress-activated protein kinases.
Infection and immunity 2001;69(4):2675-83.
2001: Paris F; Grassmé H; Cremesti A; Zager J; Fong Y; Haimovitz-Friedman A; Fuks Z; Gulbins E; Kolesnick R
Natural ceramide reverses Fas resistance of acid sphingomyelinase(-/-) hepatocytes.
The Journal of biological chemistry 2001;276(11):8297-305.
2001: Lozano J; Morales A; Cremesti A; Fuks Z; Tilly J L; Schuchman E; Gulbins E; Kolesnick R
Niemann-Pick Disease versus acid sphingomyelinase deficiency.
Cell death and differentiation 2001;8(1):100-3.
2001: Esen M; Grassmé H; Riethmüller J; Riehle A; Fassbender K; Gulbins E
Invasion of human epithelial cells by Pseudomonas aeruginosa involves src-like tyrosine kinases p60Src and p59Fyn.
Infection and immunity 2001;69(1):281-7.
2000: Lang F; Madlung J; Bock J; Lükewille U; Kaltenbach S; Lang K S; Belka C; Wagner C A; Lang H J; Gulbins E; Lepple-Wienhues A
Inhibition of Jurkat-T-lymphocyte Na+/H+-exchanger by CD95(Fas/Apo-1)-receptor stimulation.
Pflügers Archiv : European journal of physiology 2000;440(6):902-7.
2000: Grassmé H; Kirschnek S; Riethmueller J; Riehle A; von Kürthy G; Lang F; Weller M; Gulbins E
CD95/CD95 ligand interactions on epithelial cells in host defense to Pseudomonas aeruginosa.
Science (New York, N.Y.) 2000;290(5491):527-30.
2000: Gulbins E; Jekle A; Ferlinz K; Grassmé H; Lang F
Physiology of apoptosis.
American journal of physiology. Renal physiology 2000;279(4):F605-15.
2000: Kirschnek S; Paris F; Weller M; Grassme H; Ferlinz K; Riehle A; Fuks Z; Kolesnick R; Gulbins E
CD95-mediated apoptosis in vivo involves acid sphingomyelinase.
The Journal of biological chemistry 2000;275(35):27316-23.
2000: Hauck C R; Grassmé H; Bock J; Jendrossek V; Ferlinz K; Meyer T F; Gulbins E
Acid sphingomyelinase is involved in CEACAM receptor-mediated phagocytosis of Neisseria gonorrhoeae.
FEBS letters 2000;478(3):260-6.
2000: Jekle A; Obst R; Lang F; Rammensee H G; Gulbins E
CD95/CD95 ligand-mediated counterattack does not block T cell cytotoxicity.
Biochemical and biophysical research communications 2000;272(2):395-9.
2000: Lang F; Madlung J; Siemen D; Ellory C; Lepple-Wienhues A; Gulbins E
The involvement of caspases in the CD95(Fas/Apo-1)- but not swelling-induced cellular taurine release from Jurkat T-lymphocytes.
Pflügers Archiv : European journal of physiology 2000;440(1):93-9.
2000: Lang F; Ritter M; Gamper N; Huber S; Fillon S; Tanneur V; Lepple-Wienhues A; Szabo I; Gulbins E
Cell volume in the regulation of cell proliferation and apoptotic cell death.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2000;10(5-6):417-28.
2000: Lepple-Wienhues A; Szabò I; Wieland U; Heil L; Gulbins E; Lang F
Tyrosine kinases open lymphocyte chloride channels.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2000;10(5-6):307-12.
2000: Uhlemann A C; Müller C; Madlung J; Gulbins E; Lang F
Inhibition of CD95/Fas-induced DNA degradation by osmotic cell shrinkage.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2000;10(4):219-28.
2000: Gulbins E; Kolesnick R
Measurement of sphingomyelinase activity.
Methods in enzymology 2000;322():382-8.
1999: Lepple-Wienhues A; Belka C; Laun T; Jekle A; Walter B; Wieland U; Welz M; Heil L; Kun J; Busch G; Weller M; Bamberg M; Gulbins E; Lang F
Stimulation of CD95 (Fas) blocks T lymphocyte calcium channels through sphingomyelinase and sphingolipids.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(24):13795-800.
1999: Hauck C R; Gulbins E; Lang F; Meyer T F
Tyrosine phosphatase SHP-1 is involved in CD66-mediated phagocytosis of Opa52-expressing Neisseria gonorrhoeae.
Infection and immunity 1999;67(10):5490-4.
1999: Belka C; Marini P; Lepple-Wienhues A; Budach W; Jekle A; Los M; Lang F; Schulze-Osthoff K; Gulbins E; Bamberg M
The tyrosine kinase lck is required for CD95-independent caspase-8 activation and apoptosis in response to ionizing radiation.
Oncogene 1999;18(35):4983-92.
1999: Roller A; Bähr O R; Streffer J; Winter S; Heneka M; Deininger M; Meyermann R; Naumann U; Gulbins E; Weller M
Selective potentiation of drug cytotoxicity by NSAID in human glioma cells: the role of COX-1 and MRP.
Biochemical and biophysical research communications 1999;259(3):600-5.
1999: Lang F; Uhlemann A C; Lepple-Wienhues A; Szabo I; Siemen D; Nilius B; Gulbins E
Cell volume regulatory mechanisms in apoptotic cell death.
Herz 1999;24(3):232-5.
1999: Junge S; Brenner B; Lepple-Wienhues A; Nilius B; Lang F; Linderkamp O; Gulbins E
Intracellular mechanisms of L-selectin induced capping.
Cellular signalling 1999;11(4):301-8.
1999: Siemen D; Loupatatzis C; Borecky J; Gulbins E; Lang F
Ca2+-activated K channel of the BK-type in the inner mitochondrial membrane of a human glioma cell line.
Biochemical and biophysical research communications 1999;257(2):549-54.
1998: Wagenknecht B; Schulz J B; Gulbins E; Weller M
Crm-A, bcl-2 and NDGA inhibit CD95L-induced apoptosis of malignant glioma cells at the level of caspase 8 processing.
Cell death and differentiation 1998;5(10):894-900.
1998: Brenner B; Grassmé H U; Müller C; Lang F; Speer C P; Gulbins E
L-selectin stimulates the neutral sphingomyelinase and induces release of ceramide.
Experimental cell research 1998;243(1):123-8.
1998: Lang F; Madlung J; Uhlemann A C; Risler T; Gulbins E
Cellular taurine release triggered by stimulation of the Fas(CD95) receptor in Jurkat lymphocytes.
Pflügers Archiv : European journal of physiology 1998;436(3):377-83.
1998: Belka C; Marini P; Budach W; Schulze-Osthoff K; Lang F; Gulbins E; Bamberg M
Radiation-induced apoptosis in human lymphocytes and lymphoma cells critically relies on the up-regulation of CD95/Fas/APO-1 ligand.
Radiation research 1998;149(6):588-95.
1998: Szabò I; Lepple-Wienhues A; Kaba K N; Zoratti M; Gulbins E; Lang F
Tyrosine kinase-dependent activation of a chloride channel in CD95-induced apoptosis in T lymphocytes.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(11):6169-74.
1998: Lepple-Wienhues A; Szabò I; Laun T; Kaba N K; Gulbins E; Lang F
The tyrosine kinase p56lck mediates activation of swelling-induced chloride channels in lymphocytes.
The Journal of cell biology 1998;141(1):281-6.
1998: Gulbins E; Hermisson M; Brenner B; Grassmé H U; Linderkamp O; Dichgans J; Weller M; Lang F
Cellular stimulation via CD95 involves activation of phospho-inositide-3-kinase.
Pflügers Archiv : European journal of physiology 1998;435(4):546-54.
1998: Gulbins E; Brenner B; Koppenhoefer U; Linderkamp O; Lang F
Fas or ceramide induce apoptosis by Ras-regulated phosphoinositide-3-kinase activation.
Journal of leukocyte biology 1998;63(2):253-63.
1998: Brenner B; Ferlinz K; Grassmé H; Weller M; Koppenhoefer U; Dichgans J; Sandhoff K; Lang F; Gulbins E
Fas/CD95/Apo-I activates the acidic sphingomyelinase via caspases.
Cell death and differentiation 1998;5(1):29-37.
1998: Lang F; Busch G L; Ritter M; Völkl H; Waldegger S; Gulbins E; Häussinger D
Functional significance of cell volume regulatory mechanisms.
Physiological reviews 1998;78(1):247-306.
1998: Hauck C R; Meyer T F; Lang F; Gulbins E
CD66-mediated phagocytosis of Opa52 Neisseria gonorrhoeae requires a Src-like tyrosine kinase- and Rac1-dependent signalling pathway.
The EMBO journal 1998;17(2):443-54.
1998: Lang F; Lepple-Wienhues A; Paulmichl M; Szabó I; Siemen D; Gulbins E
Ion channels, cell volume, and apoptotic cell death.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 1998;8(6):285-92.
1998: Lang F; Lepple-Wienhues A; Szabó I; Siemen D; Gulbins E
Cell volume in cell proliferation and apoptotic cell death.
Contributions to nephrology 1998;123():158-68.
1997: Brenner B; Koppenhoefer U; Grassmé H; Kun J; Lang F; Gulbins E
Evidence for a novel function of the CD40 ligand as a signalling molecule in T-lymphocytes.
FEBS letters 1997;417(3):301-6.
1997: Grassmé H; Gulbins E; Brenner B; Ferlinz K; Sandhoff K; Harzer K; Lang F; Meyer T F
Acidic sphingomyelinase mediates entry of N. gonorrhoeae into nonphagocytic cells.
Cell 1997;91(5):605-15.
1997: Brenner B; Weinmann S; Grassmé H; Lang F; Linderkamp O; Gulbins E
L-selectin activates JNK via src-like tyrosine kinases and the small G-protein Rac.
Immunology 1997;92(2):214-9.
1997: Uhlemann A C; Brenner B; Gulbins E; Linderkamp O; Lang F
Stimulation of TK1 lymphoma cells via alpha 4 beta 7 integrin results in activation of src-tyrosine- and MAP-kinases.
Biochemical and biophysical research communications 1997;239(1):68-73.
1997: Brenner B; Koppenhoefer U; Lepple-Wienhues A; Grassmé H; Müller C; Speer C P; Lang F; Gulbins E
The CD40 ligand directly activates T-lymphocytes via tyrosine phosphorylation dependent PKC activation.
Biochemical and biophysical research communications 1997;239(1):11-7.
1997: Koppenhoefer U; Brenner B; Lang F; Gulbins E
The CD40-ligand stimulates T-lymphocytes via the neutral sphingomyelinase: a novel function of the CD40-ligand as signalling molecule.
FEBS letters 1997;414(2):444-8.
1997: Brenner B; Koppenhoefer U; Weinstock C; Linderkamp O; Lang F; Gulbins E
Fas- or ceramide-induced apoptosis is mediated by a Rac1-regulated activation of Jun N-terminal kinase/p38 kinases and GADD153.
The Journal of biological chemistry 1997;272(35):22173-81.
1997: Gulbins E; Welsch J; Lepple-Wienhuis A; Heinle H; Lang F
Inhibition of Fas-induced apoptotic cell death by osmotic cell shrinkage.
Biochemical and biophysical research communications 1997;236(2):517-21.
1997: Gulbins E; Szabo I; Baltzer K; Lang F
Ceramide-induced inhibition of T lymphocyte voltage-gated potassium channel is mediated by tyrosine kinases.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(14):7661-6.
1997: Wagenknecht B; Gulbins E; Lang F; Dichgans J; Weller M
Lipoxygenase inhibitors block CD95 ligand-mediated apoptosis of human malignant glioma cells.
FEBS letters 1997;409(1):17-23.
1997: Szabó I; Nilius B; Zhang X; Busch A E; Gulbins E; Suessbrich H; Lang F
Inhibitory effects of oxidants on n-type K+ channels in T lymphocytes and Xenopus oocytes.
Pflügers Archiv : European journal of physiology 1997;433(5):626-32.
1997: Brenner B; Gulbins E; Busch G L; Koppenhoefer U; Lang F; Linderkamp O
L-selectin regulates actin polymerisation via activation of the small G-protein Rac2.
Biochemical and biophysical research communications 1997;231(3):802-7.
1996: Brenner B; Gulbins E; Schlottmann K; Koppenhoefer U; Busch G L; Walzog B; Steinhausen M; Coggeshall K M; Linderkamp O; Lang F
L-selectin activates the Ras pathway via the tyrosine kinase p56lck.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(26):15376-81.
1996: Busch G L; Wiesinger H; Gulbins E; Wagner H J; Hamprecht B; Lang F
Effect of astroglial cell swelling on pH of acidic intracellular compartments.
Biochimica et biophysica acta 1996;1285(2):212-8.
1996: Gulbins E; Brenner B; Schlottmann K; Welsch J; Heinle H; Koppenhoefer U; Linderkamp O; Coggeshall K M; Lang F
Fas-induced programmed cell death is mediated by a Ras-regulated O2- synthesis.
Immunology 1996;89(2):205-12.
1996: Busch G L; Völkl H; Ritter M; Gulbins E; Häussinger D; Lang F
Water, electrolyte and acid base disturbances in renal insufficiency. Physiological and pathophysiological significance of cell volume.
Clinical nephrology 1996;46(4):270-3.
1996: Schlottmann K E; Gulbins E; Lau S M; Coggeshall K M
Activation of Src-family tyrosine kinases during Fas-induced apoptosis.
Journal of leukocyte biology 1996;60(4):546-54.
1996: Gulbins E; Coggeshall K M; Brenner B; Schlottmann K; Linderkamp O; Lang F
Fas-induced apoptosis is mediated by activation of a Ras and Rac protein-regulated signaling pathway.
The Journal of biological chemistry 1996;271(42):26389-94.
1996: Gulbins E; Brenner B; Schlottmann K; Koppenhoefer U; Linderkamp O; Coggeshall K M; Lang F
Activation of the Ras signaling pathway by the CD40 receptor.
Journal of immunology (Baltimore, Md. : 1950) 1996;157(7):2844-50.
1996: Szabò I; Gulbins E; Apfel H; Zhang X; Barth P; Busch A E; Schlottmann K; Pongs O; Lang F
Tyrosine phosphorylation-dependent suppression of a voltage-gated K+ channel in T lymphocytes upon Fas stimulation.
The Journal of biological chemistry 1996;271(34):20465-9.
1995: Gulbins E; Schlottmann K; Brenner B; Lang F; Coggeshall K M
Molecular analysis of Ras activation by tyrosine phosphorylated Vav.
Biochemical and biophysical research communications 1995;217(3):876-85.
1995: Zörnig M; Busch G; Beneke R; Gulbins E; Lang F; Ma A; Korsmeyer S; Möröy T
Survival and death of prelymphomatous B-cells from N-myc/bcl-2 double transgenic mice correlates with the regulation of intracellular Ca2+ fluxes.
Oncogene 1995;11(10):2165-74.
1995: Waldegger S; Schmidt F; Herzer T; Gulbins E; Schuster A; Biber J; Markovich D; Murer H; Busch A E; Lang F
Heavy metal mediated inhibition of rBAT-induced amino acid transport.
Kidney international 1995;47(6):1677-81.
1995: Gulbins E; Bissonnette R; Mahboubi A; Martin S; Nishioka W; Brunner T; Baier G; Baier-Bitterlich G; Byrd C; Lang F
FAS-induced apoptosis is mediated via a ceramide-initiated RAS signaling pathway.
Immunity 1995;2(4):341-51.
1995: Baier-Bitterlich G; Baier G; Gulbins E; Coggeshall K M; Altman A
The role of p56lck in CD4-mediated suppression of CD3-induced early signaling events in T lymphocytes.
Life sciences 1995;56(15):1287-97.
1995: Busch A E; Waldegger S; Herzer T; Raber G; Gulbins E; Takumi T; Moriyoshi K; Nakanishi S; Lang F
Molecular basis of IsK protein regulation by oxidation or chelation.
The Journal of biological chemistry 1995;270(8):3638-41.
1995: Raber G; Waldegger S; Herzer T; Gulbins E; Murer H; Busch A E; Lang F
The nitroso-donor S-nitroso-cysteine regulates IsK expressed in Xenopus oocytes via a c-GMP independent mechanism.
Biochemical and biophysical research communications 1995;207(1):195-201.
1995: Lang F; Busch G L; Gulbins E
Physiology of cell survival and cell death: implications for organ conservation.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 1995;10(9):1551-5.
1995: Gulbins E; Brenner B; Lang F
Molecular mechanisms of lymphocyte activation.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 1995;10(9):1533-5.
1994: Gulbins E; Coggeshall K M; Baier G; Telford D; Langlet C; Baier-Bitterlich G; Bonnefoy-Berard N; Burn P; Wittinghofer A; Altman A
Direct stimulation of Vav guanine nucleotide exchange activity for Ras by phorbol esters and diglycerides.
Molecular and cellular biology 1994;14(7):4749-58.
1994: Schlottmann K; Gulbins E; Rauterberg E W; Steinhausen M
Effects of systemic complement activation on renal circulation of rats.
European journal of clinical investigation 1994;24(5):320-30.
1994: Gulbins E; Langlet C; Baier G; Bonnefoy-Berard N; Herbert E; Altman A; Coggeshall K M
Tyrosine phosphorylation and activation of Vav GTP/GDP exchange activity in antigen receptor-triggered B cells.
Journal of immunology (Baltimore, Md. : 1950) 1994;152(5):2123-9.
1994: Gulbins E; Coggeshall K M; Langlet C; Baier G; Bonnefoy-Berard N; Burn P; Wittinghofer A; Katzav S; Altman A
Activation of Ras in vitro and in intact fibroblasts by the Vav guanine nucleotide exchange protein.
Molecular and cellular biology 1994;14(2):906-13.
1993: Gulbins E; Hoffend J; Zou A P; Dietrich M S; Schlottmann K; Cavarape A; Steinhausen M
Endothelin and endothelium-derived relaxing factor control of basal renovascular tone in hydronephrotic rat kidneys.
The Journal of physiology 1993;469():571-82.
1993: Gulbins E; Schlottmann K; Rauterberg E W; Steinhausen M
Effects of rC5a on the circulation of normal and split hydronephrotic rat kidneys.
The American journal of physiology 1993;265(1 Pt 2):F96-103.
1993: Gulbins E; Coggeshall K M; Baier G; Katzav S; Burn P; Altman A
Tyrosine kinase-stimulated guanine nucleotide exchange activity of Vav in T cell activation.
Science (New York, N.Y.) 1993;260(5109):822-5.
1993: Gulbins E; Siow Y; Vitale G C
Complement 5a induces in vivo synthesis of cysteinyl leukotrienes in rats.
Prostaglandins, leukotrienes, and essential fatty acids 1993;48(4):331-4.
1993: Baier G; Telford D; Gulbins E; Yamada N; Kawakami T; Altman A
Improved specificity of RT-PCR amplifications using nested cDNA primers.
Nucleic acids research 1993;21(5):1329-30.
1991: Fretschner M; Endlich K; Gulbins E; Lang R E; Schlottmann K; Steinhausen M
Effects of endothelin on the renal microcirculation of the split hydronephrotic rat kidney.
Renal physiology and biochemistry 1991;14(3):112-27.
1991: Gulbins E; Parekh N; Rauterberg E W; Schlottmann K; Steinhausen M
Cysteinyl leukotriene actions on the microcirculation of the normal and split hydronephrotic rat kidney.
European journal of clinical investigation 1991;21(2):184-96.

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