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Ginette Gunz

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Tullio Florio; Federica Barbieri; Renato Spaziante; Gianluigi Zona; Leo J Hofland; Peter M Van Koetsveld; Richard A Feelders; Günter K Stalla; Marily Theodoropoulou; Michael D Culler; Jesse Dong; John E Taylor; Jacques-Pierre Moreau; Alexandru Saveanu; Ginette Gunz; Henry Dufour; Philippe Jaquet
Efficacy of a dopamine-somatostatin chimeric molecule, BIM-23A760, in the control of cell growth from primary cultures of human non-functioning pituitary adenomas: a multi-center study.
Alessandra Fusco; Ginette Gunz; Philippe Jaquet; Henry Dufour; Anne Laure Germanetti; Michael D Culler; Anne Barlier; Alexandru Saveanu
Somatostatinergic ligands in dopamine-sensitive and -resistant prolactinomas.
Dermot O'Toole; Alexandru Saveanu; Anne Couvelard; Ginette Gunz; Alain Enjalbert; Philippe Jaquet; Philippe Ruszniewski; Anne Barlier
The analysis of quantitative expression of somatostatin and dopamine receptors in gastro-entero-pancreatic tumours opens new therapeutic strategies.

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All Publications

2008: Tullio Florio; Federica Barbieri; Renato Spaziante; Gianluigi Zona; Leo J Hofland; Peter M Van Koetsveld; Richard A Feelders; Günter K Stalla; Marily Theodoropoulou; Michael D Culler; Jesse Dong; John E Taylor; Jacques-Pierre Moreau; Alexandru Saveanu; Ginette Gunz; Henry Dufour; Philippe Jaquet
Efficacy of a dopamine-somatostatin chimeric molecule, BIM-23A760, in the control of cell growth from primary cultures of human non-functioning pituitary adenomas: a multi-center study.
Endocrine-related cancer 2008;15(2):583-96.
2008: Alessandra Fusco; Ginette Gunz; Philippe Jaquet; Henry Dufour; Anne Laure Germanetti; Michael D Culler; Anne Barlier; Alexandru Saveanu
Somatostatinergic ligands in dopamine-sensitive and -resistant prolactinomas.
European journal of endocrinology / European Federation of Endocrine Societies 2008;158(5):595-603.
2006: Dermot O'Toole; Alexandru Saveanu; Anne Couvelard; Ginette Gunz; Alain Enjalbert; Philippe Jaquet; Philippe Ruszniewski; Anne Barlier
The analysis of quantitative expression of somatostatin and dopamine receptors in gastro-entero-pancreatic tumours opens new therapeutic strategies.
European journal of endocrinology / European Federation of Endocrine Societies 2006;155(6):849-57.
2006: Isabelle Pellegrini; Cathy Roche; Marie-Helene Quentien; Mireille Ferrand; Ginette Gunz; S thirion; Claude BAGNIS; Alain Enjalbert; Jean-Louis Franc
Involvement of the pituitary-specific transcription factor pit-1 in somatolactotrope cell growth and death: an approach using dominant-negative pit-1 mutants.
Molecular endocrinology (Baltimore, Md.) 2006;20(12):3212-27.
2006: Alexandru Saveanu; Ginette Gunz; Severine Guillen; Henry Dufour; Michael D Culler; Philippe Jaquet
Somatostatin and dopamine-somatostatin multiple ligands directed towards somatostatin and dopamine receptors in pituitary adenomas.
Neuroendocrinology 2006;83(3-4):258-63.
2005: Philippe Jaquet; Ginette Gunz; Alexandru Saveanu; Henry Dufour; John Taylor; Josse Dong; Sun Kim; Jacques-Pierre Moreau; Alain Enjalbert; Michael D Culler
Efficacy of chimeric molecules directed towards multiple somatostatin and dopamine receptors on inhibition of GH and prolactin secretion from GH-secreting pituitary adenomas classified as partially responsive to somatostatin analog therapy.
European journal of endocrinology / European Federation of Endocrine Societies 2005;153(1):135-41.
2005: Philippe Jaquet; Ginette Gunz; Alexandru Saveanu; Anne Barlier; Henry Dufour; John Taylor; Josse Dong; Sun Kim; Jacques-Pierre Moreau; Michael D Culler
BIM-23A760, a chimeric molecule directed towards somatostatin and dopamine receptors, vs universal somatostatin receptors ligands in GH-secreting pituitary adenomas partial responders to octreotide.
Journal of endocrinological investigation 2005;28(11 Suppl International):21-7.
2003: Alexandru Saveanu; Ginette Gunz; Henry Dufour; Alain Enjalbert; Michael D Culler; Philippe Jaquet
Distribution and functionality of the somatostatin receptor subtypes in acromegaly.
Journal of endocrinological investigation 2003;26(8 Suppl):4-7.
2002: Alexandru Saveanu; Esteban Lavaque; Ginette Gunz; Anne Barlier; Sun Kim; John E Taylor; Michael D Culler; Alain Enjalbert; Philippe Jaquet
Demonstration of enhanced potency of a chimeric somatostatin-dopamine molecule, BIM-23A387, in suppressing growth hormone and prolactin secretion from human pituitary somatotroph adenoma cells.
The Journal of clinical endocrinology and metabolism 2002;87(12):5545-52.
2002: Marie-Helene Quentien; Isabelle Manfroid; Daniel Moncet; Ginette Gunz; Marc Muller; Michel Grino; Alain Enjalbert; Isabelle Pellegrini
Pitx factors are involved in basal and hormone-regulated activity of the human prolactin promoter.
The Journal of biological chemistry 2002;277(46):44408-16.
2002: Marie-Helene Quentien; Fabián Pitoia; Ginette Gunz; Marie-Pierre Guillet; Alain Enjalbert; Isabelle Pellegrini
Regulation of prolactin, GH, and Pit-1 gene expression in anterior pituitary by Pitx2: An approach using Pitx2 mutants.
Endocrinology 2002;143(8):2839-51.
2002: Sophie Vallette-Kasic; Isabelle Morange-Ramos; Adel Selim; Ginette Gunz; Sophie Morange; Alain Enjalbert; Pierre-Marie Martin; Philippe Jaquet; Thierry Brue
Macroprolactinemia revisited: a study on 106 patients.
The Journal of clinical endocrinology and metabolism 2002;87(2):581-8.
2001: Alexandru Saveanu; Isabelle Morange-Ramos; Ginette Gunz; Henry Dufour; Alain Enjalbert; Philippe Jaquet
A luteinizing hormone-, alpha-subunit- and prolactin-secreting pituitary adenoma responsive to somatostatin analogs: in vivo and in vitro studies.
European journal of endocrinology / European Federation of Endocrine Societies 2001;145(1):35-41.
2001: Sophie Vallette-Kasic; Isabelle Pellegrini-Bouiller; François Sampieri; Ginette Gunz; A Diaz; Sally Radovick; Alain Enjalbert; Thierry Brue
Combined pituitary hormone deficiency due to the F135C human Pit-1 (pituitary-specific factor 1) gene mutation: functional and structural correlates.
Molecular endocrinology (Baltimore, Md.) 2001;15(3):411-20.
2001: Alexandru Saveanu; Ginette Gunz; Henry Dufour; P Caron; Frederic Fina; L'Houcine Ouafik; Michael D Culler; Jacques-Pierre Moreau; Alain Enjalbert; Philippe Jaquet
Bim-23244, a somatostatin receptor subtype 2- and 5-selective analog with enhanced efficacy in suppressing growth hormone (GH) from octreotide-resistant human GH-secreting adenomas.
The Journal of clinical endocrinology and metabolism 2001;86(1):140-5.
2000: Philippe Jaquet; Alexandru Saveanu; Ginette Gunz; Frederic Fina; Alfredo J Zamora; Michel Grino; Michael D Culler; Jacques-Pierre Moreau; Alain Enjalbert; L'Houcine Ouafik
Human somatostatin receptor subtypes in acromegaly: distinct patterns of messenger ribonucleic acid expression and hormone suppression identify different tumoral phenotypes.
The Journal of clinical endocrinology and metabolism 2000;85(2):781-92.
1999: Philippe Jaquet; L'Houcine Ouafik; Alexandru Saveanu; Ginette Gunz; Frederic Fina; Henry Dufour; Michael D Culler; Jacques-Pierre Moreau; Alain Enjalbert
Quantitative and functional expression of somatostatin receptor subtypes in human prolactinomas.
The Journal of clinical endocrinology and metabolism 1999;84(9):3268-76.
1999: Anne Barlier; Isabelle Pellegrini-Bouiller; Ginette Gunz; Alfredo J Zamora; Philippe Jaquet; Alain Enjalbert
Impact of gsp oncogene on the expression of genes coding for Gsalpha, Pit-1, Gi2alpha, and somatostatin receptor 2 in human somatotroph adenomas: involvement in octreotide sensitivity.
The Journal of clinical endocrinology and metabolism 1999;84(8):2759-65.
1999: Anne Barlier; Alfredo J Zamora; Michel Grino; Ginette Gunz; Isabelle Pellegrini-Bouiller; Isabelle Morange-Ramos; Dominique Figarella-Branger; Henry Dufour; Philippe Jaquet; Alain Enjalbert
Expression of functional growth hormone secretagogue receptors in human pituitary adenomas: polymerase chain reaction, triple in-situ hybridization and cell culture studies.
Journal of neuroendocrinology 1999;11(7):491-502.
1999: Isabelle Pellegrini-Bouiller; C Manrique; Ginette Gunz; Michel Grino; Alfredo J Zamora; Dominique Figarella-Branger; François Grisoli; Philippe Jaquet; Alain Enjalbert
Expression of the members of the Ptx family of transcription factors in human pituitary adenomas.
The Journal of clinical endocrinology and metabolism 1999;84(6):2212-20.
1998: Anne Barlier; Ginette Gunz; Alfredo J Zamora; Isabelle Morange-Ramos; Dominique Figarella-Branger; Henry Dufour; Alain Enjalbert; Philippe Jaquet
Pronostic and therapeutic consequences of Gs alpha mutations in somatotroph adenomas.
The Journal of clinical endocrinology and metabolism 1998;83(5):1604-10.
1997: Anne Barlier; Isabelle Pellegrini-Bouiller; Ginette Gunz; Philippe Jaquet; Alain Enjalbert
[Homeoproteins and pituitary adenoma].
Annales d'endocrinologie 1997;58(1):3-10.
1997: Isabelle Pellegrini-Bouiller; Isabelle Morange-Ramos; Anne Barlier; Ginette Gunz; Alain Enjalbert; Philippe Jaquet
Pit-1 gene expression in human pituitary adenomas.
Hormone research 1997;47(4-6):251-8.
1997: Anne Barlier; Isabelle Pellegrini-Bouiller; L Caccavelli; Ginette Gunz; Isabelle Morange-Ramos; Philippe Jaquet; Alain Enjalbert
Abnormal transduction mechanisms in pituitary adenomas.
Hormone research 1997;47(4-6):227-34.
1996: Isabelle Pellegrini-Bouiller; Isabelle Morange-Ramos; Anne Barlier; Ginette Gunz; Dominique Figarella-Branger; C Cortet-Rudelli; F Grisoli; Philippe Jaquet; Alain Enjalbert
Pit-1 gene expression in human lactotroph and somatotroph pituitary adenomas is correlated to D2 receptor gene expression.
The Journal of clinical endocrinology and metabolism 1996;81(9):3390-6.
1996: Isabelle Pellegrini-Bouiller; P Bélicar; Anne Barlier; Ginette Gunz; J P Charvet; Philippe Jaquet; Thierry Brue; Bernard Vialettes; Alain Enjalbert
A new mutation of the gene encoding the transcription factor Pit-1 is responsible for combined pituitary hormone deficiency.
The Journal of clinical endocrinology and metabolism 1996;81(8):2790-6.
1994: I Pellegrini; Anne Barlier; Ginette Gunz; Dominique Figarella-Branger; Alain Enjalbert; F Grisoli; Philippe Jaquet
Pit-1 gene expression in the human pituitary and pituitary adenomas.
The Journal of clinical endocrinology and metabolism 1994;79(1):189-96.
1993: I Sergi; G Medri; M J Papandreou; Ginette Gunz; Philippe Jaquet; C Ronin
Polymorphism of thyrotropin and alpha subunit in human pituitary adenomas.
Journal of endocrinological investigation 1993;16(1):45-55.
1992: Thierry Brue; E Caruso; I Morange; T Hoffmann; M Evrin; Ginette Gunz; M Benkirane; Philippe Jaquet
Immunoradiometric analysis of circulating human glycosylated and nonglycosylated prolactin forms: spontaneous and stimulated secretions.
The Journal of clinical endocrinology and metabolism 1992;75(5):1338-44.
1992: J Bertherat; Thierry Brue; Alain Enjalbert; Ginette Gunz; R Rasolonjanahary; André Warnet; Philippe Jaquet; Jacques Epelbaum
Somatostatin receptors on thyrotropin-secreting pituitary adenomas: comparison with the inhibitory effects of octreotide upon in vivo and in vitro hormonal secretions.
The Journal of clinical endocrinology and metabolism 1992;75(2):540-6.
1992: Thierry Brue; I Pellegrini; Ginette Gunz; I Morange; D Dewailly; J Brownell; Alain Enjalbert; Philippe Jaquet
Effects of the dopamine agonist CV 205-502 in human prolactinomas resistant to bromocriptine.
The Journal of clinical endocrinology and metabolism 1992;74(3):577-84.
1992: T Hoffmann; Ginette Gunz; Thierry Brue; Philippe Jaquet; C Ronin
Prolactin isoforms secreted by human prolactinomas.
Hormone research 1992;38(3-4):164-70.
1992: I Morange; D Figarella-Branger; Ginette Gunz; Thierry Brue; Philippe Jaquet
[Value of alpha subunit assay in pituitary pathology].
Annales d'endocrinologie 1992;53(4):138-46.
1990: I Pellegrini; Ginette Gunz; F Grisoli; Philippe Jaquet
Different pathways of secretion for glycosylated and nonglycosylated human prolactin.
Endocrinology 1990;126(2):1087-95.
1989: I Pellegrini; R Rasolonjanahary; Ginette Gunz; P Bertrand; S Delivet; C P Jedynak; Claude Kordon; F Peillon; Philippe Jaquet; Alain Enjalbert
Resistance to bromocriptine in prolactinomas.
The Journal of clinical endocrinology and metabolism 1989;69(3):500-9.
1988: I Pellegrini; Ginette Gunz; C Ronin; E Fenouillet; J P Peyrat; P Delori; Philippe Jaquet
Polymorphism of prolactin secreted by human prolactinoma cells: immunological, receptor binding, and biological properties of the glycosylated and nonglycosylated forms.
Endocrinology 1988;122(6):2667-74.
1988: Michel Grino; Françoise Boudouresque; B Conte-Devolx; Ginette Gunz; F Grisoli; Charles Oliver; Philippe Jaquet
In vitro corticotropin-releasing hormone (CRH) stimulation of adrenocorticotropin release from corticotroph adenoma cells: effect of prolonged exposure to CRH and its interaction with cortisol.
The Journal of clinical endocrinology and metabolism 1988;66(4):770-5.
1985: Elias Castanas; Philippe Jaquet; Ginette Gunz; P Cantau; P Giraud
Direct action of opiates on bromocriptine-inhibited prolactin release by human prolactinoma cells in primary culture.
The Journal of clinical endocrinology and metabolism 1985;61(5):963-8.
1985: J Hassoun; Philippe Jaquet; B Devictor; C Andonian; F Grisoli; Ginette Gunz; M Toga
Bromocriptine effects on cultured human prolactin-producing pituitary adenomas: in vitro ultrastructural, morphometric, and immunoelectron microscopic studies.
The Journal of clinical endocrinology and metabolism 1985;61(4):686-92.
1985: Philippe Jaquet; Ginette Gunz; F Grisoli
Hormonal regulation of prolactin release by human prolactinoma cells cultured in serum-free conditions.
Hormone research 1985;22(3):153-63.
1984: Philippe Jaquet; J Hassoun; P Delori; Ginette Gunz; F Grisoli; Bruce D Weintraub
A human pituitary adenoma secreting thyrotropin and prolactin: immunohistochemical, biochemical, and cell culture studies.
The Journal of clinical endocrinology and metabolism 1984;59(5):817-24.
1983: Françoise Boudouresque; M Trigano; B Conte-Devolx; P Giraud; Elias Castanas; Ginette Gunz; C Oliver
[Molecular forms of pituitary and plasma ACTH in physiology and pathology].
Annales d'endocrinologie 1983;44(1):9-14.
1982: P Giraud; Elias Castanas; Charles Oliver; B Conte-Devolx; Françoise Boudouresque; H Taquet; M Orlando; P Jaquet; L Eiden; F Cesselin; Ginette Gunz; M Trigano
Enkephalins in human pheochromocytoma biosynthesis and secretion.
European heart journal 1982;3 Suppl C():19-22.