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Goutam Gupta

Research Profile

Concepts & Ideas

Phenomena

Chemicals & Drugs

Genes & Molecular Sequences

Disorders

Fragile X Syndrome

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Publications

TOP 3
Abhaya M Dandekar; Paul A Feldstein; Luiz R Goulart; Hossein Gouran; Cecilia B Agüero; Yasmin Borhani; George Bruening; Anu Chaudhary; Edwin L Civerolo; Ana María Ibáñez; Sarah McFarland; Rafael Nascimento; Meghan Norvell; Paige E Pardington; Sandra L Uratsu; Goutam Gupta
An engineered innate immune defense protects grapevines from Pierce disease.
Abhaya M Dandekar; Federico Martinelli; Cristina E Davis; Abhinav Bhushan; Weixiang Zhao; Oliver Fiehn; Kirsten Skogerson; Gert Wohlgemuth; Raissa D'Souza; Soumen Roy; Russell L Reagan; Dawei Lin; Robert B Cary; Paige Pardington; Goutam Gupta
Analysis of early host responses for asymptomatic disease detection and management of specialty crops.
Ahmet Zeytun; Anu Chaudhary; Paige Pardington; Robert B Cary; Goutam Gupta
Induction of cytokines and chemokines by Toll-like receptor signaling: strategies for control of inflammation.

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All Publications

2012: Abhaya M Dandekar; Paul A Feldstein; Luiz R Goulart; Hossein Gouran; Cecilia B Agüero; Yasmin Borhani; George Bruening; Anu Chaudhary; Edwin L Civerolo; Ana María Ibáñez; Sarah McFarland; Rafael Nascimento; Meghan Norvell; Paige E Pardington; Sandra L Uratsu; Goutam Gupta
An engineered innate immune defense protects grapevines from Pierce disease.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(10):3721-5.
2010: Abhaya M Dandekar; Federico Martinelli; Cristina E Davis; Abhinav Bhushan; Weixiang Zhao; Oliver Fiehn; Kirsten Skogerson; Gert Wohlgemuth; Raissa D'Souza; Soumen Roy; Russell L Reagan; Dawei Lin; Robert B Cary; Paige Pardington; Goutam Gupta
Analysis of early host responses for asymptomatic disease detection and management of specialty crops.
Critical reviews in immunology 2010;30(3):277-89.
2010: Ahmet Zeytun; Anu Chaudhary; Paige Pardington; Robert B Cary; Goutam Gupta
Induction of cytokines and chemokines by Toll-like receptor signaling: strategies for control of inflammation.
Critical reviews in immunology 2010;30(1):53-67.
2009: Shannon Silva; Kumkum Ganguly; Theresa M Fresquez; Goutam Gupta; T Mark McCleskey; Anu Chaudhary
Beryllium alters lipopolysaccharide-mediated intracellular phosphorylation and cytokine release in human peripheral blood mononuclear cells.
Journal of occupational and environmental hygiene 2009;6(12):775-82.
2008: Momchilo Vuyisich; S Gnanakaran; Julie A Lovchik; C Rick Lyons; Goutam Gupta
A dual-purpose protein ligand for effective therapy and sensitive diagnosis of anthrax.
The protein journal 2008;27(5):292-302.
2007: Meghan Kunkel; Momchilo Vuyisich; Gnana Gnanakaran; George E Bruening; Abhaya M Dandekar; Edwin Civerolo; John J Marchalonis; Goutam Gupta
Rapid clearance of bacteria and their toxins: development of therapeutic proteins.
Critical reviews in immunology 2007;27(3):233-45.
2007: Ahmet Zeytun; Jennifer C Van Velkinburgh; Paige E Pardington; Robert R Cary; Goutam Gupta
Pathogen-specific innate immune response.
Advances in experimental medicine and biology 2007;598():342-57.
2006: Elizabeth Hong-Geller; Paige E Pardington; Robert B Cary; Nancy N Sauer; Goutam Gupta
Chemokine regulation in response to beryllium exposure in human peripheral blood mononuclear and dendritic cells.
Toxicology 2006;218(2-3):216-28.
2005: Margit Möllhoff; Hannah B Vander Zanden; Patrick R Shiflett; Goutam Gupta
Modeling of receptor mimics that inhibit superantigen pathogenesis.
Journal of molecular recognition : JMR 2005;18(1):73-83.
2004: S V Santhana Mariappan; Xun Cheng; Richard B Van Breemen; Louis A Silks; Goutam Gupta
Analysis of GAA/TTC DNA triplexes using nuclear magnetic resonance and electrospray ionization mass spectrometry.
Analytical biochemistry 2004;334(2):216-26.
2004: Anu Chaudhary; Nancy N Sauer; Goutam Gupta
Beryllium-specific immune response in primary cells from healthy individuals.
Toxicology 2004;201(1-3):9-19.
2004: Elizabeth Hong-Geller; Margit Möllhoff; Patrick R Shiflett; Goutam Gupta
Design of chimeric receptor mimics with different TcRVbeta isoforms. Type-specific inhibition of superantigen pathogenesis.
The Journal of biological chemistry 2004;279(7):5676-84.
2003: Patrick R Shiflett; Kirsten J Taylor-McCabe; Ryszard Michalczyk; Louis A Silks; Goutam Gupta
Structural studies on the hairpins at the 3' untranslated region of an anthrax toxin gene.
Biochemistry 2003;42(20):6078-89.
2003: Elizabeth Hong-Geller; Goutam Gupta
Therapeutic approaches to superantigen-based diseases: a review.
Journal of molecular recognition : JMR 2003;16(2):91-101.
2001: NM Lehnert; D L Allen; B L Allen; P Catasti; Patrick R Shiflett; M Chen; Bruce E Lehnert; Goutam Gupta
Structure-based design of a bispecific receptor mimic that inhibits T cell responses to a superantigen.
Biochemistry 2001;40(14):4222-8.
1999: S V Santhana Mariappan; P Catasti; Louis A Silks; E Morton Bradbury; Goutam Gupta
The high-resolution structure of the triplex formed by the GAA/TTC triplet repeat associated with Friedreich's ataxia.
Journal of molecular biology 1999;285(5):2035-52.
1999: P Catasti; Xian Chen; S V Santhana Mariappan; E Morton Bradbury; Goutam Gupta
DNA repeats in the human genome.
Genetica 1999;106(1-2):15-36.
1998: Xian Chen; S V Santhana Mariappan; JJ Kelley; John H Bushweller; E Morton Bradbury; Goutam Gupta
A PCR-based method for uniform 13C/15N labeling of long DNA oligomers.
FEBS letters 1998;436(3):372-6.
1998: Xian Chen; S V Santhana Mariappan; Robert K Moyzis; E Morton Bradbury; Goutam Gupta
Hairpin induced slippage and hyper-methylation of the fragile X DNA triplets.
Journal of biomolecular structure & dynamics 1998;15(4):745-56.
1998: S V Santhana Mariappan; Louis A Silks; Xian Chen; P A Springer; R Wu; Robert K Moyzis; E Morton Bradbury; Angel Enrique Garcia; Goutam Gupta
Solution structures of the Huntington's disease DNA triplets, (CAG)n.
Journal of biomolecular structure & dynamics 1998;15(4):723-44.
1998: S V Santhana Mariappan; Louis A Silks; E Morton Bradbury; Goutam Gupta
Fragile X DNA triplet repeats, (GCC)n, form hairpins with single hydrogen-bonded cytosine.cytosine mispairs at the CpG sites: isotope-edited nuclear magnetic resonance spectroscopy on (GCC)n with selective 15N4-labeled cytosine bases.
Journal of molecular biology 1998;283(1):111-20.
1997: P Catasti; Xian Chen; LL Deaven; Robert K Moyzis; E Morton Bradbury; Goutam Gupta
Cystosine-rich strands of the insulin minisatellite adopt hairpins with intercalated cytosine+.cytosine pairs.
Journal of molecular biology 1997;272(3):369-82.
1996: P Catasti; X Chen; R K Moyzis; E Morton Bradbury; Goutam Gupta
Structure-function correlations of the insulin-linked polymorphic region.
Journal of molecular biology 1996;264(3):534-45.
1996: P Catasti; E Morton Bradbury; Goutam Gupta
Structure and polymorphism of HIV-1 third variable loops.
The Journal of biological chemistry 1996;271(14):8236-42.
1996: S V Santhana Mariappan; P Catasti; X Chen; R Ratliff; R K Moyzis; E Morton Bradbury; Goutam Gupta
Solution structures of the individual single strands of the fragile X DNA triplets (GCC)n.(GGC)n.
Nucleic acids research 1996;24(4):784-92.
1996: S V Santhana Mariappan; A E Garcoa; Goutam Gupta
Structure and dynamics of the DNA hairpins formed by tandemly repeated CTG triplets associated with myotonic dystrophy.
Nucleic acids research 1996;24(4):775-83.
1995: J D Fontenot; S V Santhana Mariappan; P Catasti; N Domenech; Olivera J Finn; Goutam Gupta
Structure of a tumor associated antigen containing a tandemly repeated immunodominant epitope.
Journal of biomolecular structure & dynamics 1995;13(2):245-60.
1995: X Chen; S V Santhana Mariappan; P Catasti; R Ratliff; R K Moyzis; A Laayoun; S S Smith; E Morton Bradbury; Goutam Gupta
Hairpins are formed by the single DNA strands of the fragile X triplet repeats: structure and biological implications.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(11):5199-203.
1995: P Catasti; J D Fontenot; E Morton Bradbury; Goutam Gupta
Local and global structural properties of the HIV-MN V3 loop.
The Journal of biological chemistry 1995;270(5):2224-32.
1995: J D Fontenot; J M Gatewood; S V Santhana Mariappan; Chou-Pong Pau; Bharat Parekh; J Richard George; Goutam Gupta
Human immunodeficiency virus (HIV) antigens: structure and serology of multivalent human mucin MUC1-HIV V3 chimeric proteins.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(1):315-9.
1994: P Catasti; Goutam Gupta; Angel Enrique Garcia; R Ratliff; L Hong; Peter M Yau; R K Moyzis; E Morton Bradbury
Unusual structures of the tandem repetitive DNA sequences located at human centromeres.
Biochemistry 1994;33(13):3819-30.
1993: Goutam Gupta; G M Anantharamaiah; D R Scott; J H Eldridge; G Myers
Solution structure of the V3 loop of a Thailand HIV isolate.
Journal of biomolecular structure & dynamics 1993;11(2):345-66.
1993: Goutam Gupta; Angel E García; K T Hiriyanna
Sampling of the conformations of the d(CGCTGCGGC) hairpin in solution by two-dimensional nuclear magnetic resonance and theoretical methods.
Biochemistry 1993;32(3):948-60.
1990: MH Sarma; K Umemoto; Goutam Gupta; J Luo; RH Sarma
In search of a Hoogsteen base paired DNA duplex in aqueous solution.
Journal of biomolecular structure & dynamics 1990;8(3):461-82.
1990: Angel Enrique Garcia; Goutam Gupta; Dikeos Soumpasis; C S Tung
Energetics of the hairpin to mismatched duplex transition of d(GCCGCAGC) on NaCl solution.
Journal of biomolecular structure & dynamics 1990;8(1):173-86.
1990: K Umemoto; MH Sarma; Goutam Gupta; RH Sarma
Effect of the methyl group on DNA bending and curvature: structure of d(GA4U4C)2 in solution.
Biochemistry 1990;29(19):4714-22.
1990: MH Sarma; Goutam Gupta; Angel Enrique Garcia; K Umemoto; RH Sarma
Quantitative structure of a complex between a minor-groove-specific drug and a bent DNA decamer duplex: use of 2D NMR data and NOESY constrained energy minimization.
Biochemistry 1990;29(19):4723-34.
1988: Angel Enrique Garcia; Goutam Gupta; MH Sarma; RH Sarma
Stability and motion of a hairpin and the corresponding mismatched duplex: a theoretical exploration using molecular mechanics and normal mode analysis of 2D NMR results on d(GCCGCAGC).
Journal of biomolecular structure & dynamics 1988;6(3):525-42.
1988: Goutam Gupta; MH Sarma; RH Sarma
On the question of DNA bending: two-dimensional NMR studies on d(GTTTTAAAAC)2 in solution.
Biochemistry 1988;27(20):7909-19.
1988: MH Sarma; Goutam Gupta; RH Sarma
Structure of a bent DNA: two-dimensional NMR studies on d(GAAAATTTTC)2.
Biochemistry 1988;27(9):3423-32.
1987: Goutam Gupta; MH Sarma; RH Sarma; R Bald; U Engelke; S L Oei; R Gessner; V A Erdmann
DNA hairpin structures in solution: 500-MHz two-dimensional 1H NMR studies on d(CGCCGCAGC) and d(CGCCGTAGC).
Biochemistry 1987;26(24):7715-23.
1987: MH Sarma; Goutam Gupta; RH Sarma; R Bald; U Engelke; S L Oei; R Gessner; V A Erdmann
DNA structure in which an adenine-cytosine mismatch pair forms an integral part of the double helix.
Biochemistry 1987;26(24):7707-15.
1986: Goutam Gupta; MH Sarma; RH Sarma; M M Dhingra
NOE data at 500 MHz reveal the proximity of phenyl and tyrosine rings in enkephalin.
FEBS letters 1986;198(2):245-50.
1985: MH Sarma; Goutam Gupta; RH Sarma
Structure of poly(dA).poly(dT) is not identical to the AT rich regions of the single crystal structure of CGCGAATTBrCGCG. The consequence of this to netropsin binding to poly(dA).poly(dT).
Journal of biomolecular structure & dynamics 1985;3(3):433-6.
1985: MH Sarma; Goutam Gupta; RH Sarma
Untenability of the heteronomous DNA model for poly(dA).poly(dT) in solution. This DNA adopts a right-handed B-DNA duplex in which the two strands are conformationally equivalent. A 500 MHz NMR study using one dimensional NOE.
Journal of biomolecular structure & dynamics 1985;2(6):1057-84.
1985: MH Sarma; Goutam Gupta; RH Sarma
Netropsin specifically recognizes one of the two conformationally equivalent strands of poly(dA).poly(dT). One dimensional NMR study at 500 MHz involving NOE transfer between netropsin and DNA protons.
Journal of biomolecular structure & dynamics 1985;2(6):1085-95.
1984: MH Sarma; Goutam Gupta; RH Sarma
Solution structure of poly(dA-dT).poly(dA-dT) in low and high salt: a 500 MHz 1H NMR study using one-dimensional NOE.
Journal of biomolecular structure & dynamics 1984;1(6):1423-55.
1984: Goutam Gupta; MH Sarma; RH Sarma
Structure and dynamics of netropsin-poly(dA-dT).poly(dA-dT) complex: 500 MHz 1H NMR studies.
Journal of biomolecular structure & dynamics 1984;1(6):1457-72.
1983: M M Dhingra; MH Sarma; Goutam Gupta; RH Sarma
Determination of handedness of DNA double helices from NOE difference spectra: the structure of poly(dG-dC).poly(dG-dC) in low salt.
Journal of biomolecular structure & dynamics 1983;1(2):417-28.
1983: Goutam Gupta; MH Sarma; M M Dhingra; RH Sarma; M Rajagopalan; V Sasisekharan
Poly(dA-dT).poly(dA-dT) in low salt appears to be a left-handed B-helix combined use of chemical theory, fiber diffraction and NMR spectroscopy.
Journal of biomolecular structure & dynamics 1983;1(2):395-416.
1983: Goutam Gupta; M M Dhingra; RH Sarma
Left-handed intercalated DNA double helix: rendezvous of ethidium and actinomycin D in the Z-helical conformation space.
Journal of biomolecular structure & dynamics 1983;1(1):97-113.
1983: MH Sarma; Goutam Gupta; M M Dhingra; RH Sarma
During B-Z transition there is no large scale breakage of Watson-Crick base pairs. A direct demonstration using 500 MHz 1H NMR spectroscopy.
Journal of biomolecular structure & dynamics 1983;1(1):59-81.
1983: M Rajagopalan; Goutam Gupta; V Sasisekharan
Base-base interactions in nucleic acids containing A-T base pairs. Structure of poly[d(A-T)].
FEBS letters 1983;159(1-2):285-9.
1983: N Ramaswamy; M Bansal; Goutam Gupta; V Sasisekharan
Structure of D-DNA: 8-fold or 7-fold helix?
The EMBO journal 1983;2(9):1557-60.
1982: N Ramaswamy; M Bansal; Goutam Gupta; V Sasisekharan
Left-handed helices for DNA: studies on poly[d(I-C)].
Proceedings of the National Academy of Sciences of the United States of America 1982;79(20):6109-13.