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Paul Gurbel

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TOP 3
Paul A Gurbel; Udaya S Tantry
Triple antithrombotic therapy with prasugrel in the stented patient: concern for more bleeding.
Kevin P Bliden; William L Bailey; Brian A Baker; Young-Hoon Jeong; Thomas D Nolin; Udaya S Tantry; Paul A Gurbel
Thienopyridine efficacy and cigarette smoking status.
Kristopher J Swiger; Udaya S Tantry; Omair Yousuf; Kevin P Bliden; Paul A Gurbel
Cigarette smoking and clopidogrel interaction.

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All Publications

2013: Paul A Gurbel; Udaya S Tantry
Triple antithrombotic therapy with prasugrel in the stented patient: concern for more bleeding.
Journal of the American College of Cardiology 2013;61(20):2067-9.
2013: Kevin P Bliden; William L Bailey; Brian A Baker; Young-Hoon Jeong; Thomas D Nolin; Udaya S Tantry; Paul A Gurbel
Thienopyridine efficacy and cigarette smoking status.
American heart journal 2013;165(5):693-703.
2013: Kristopher J Swiger; Udaya S Tantry; Omair Yousuf; Kevin P Bliden; Paul A Gurbel
Cigarette smoking and clopidogrel interaction.
Current cardiology reports 2013;15(5):361.
2013: Udaya S Tantry; Young-Hoon Jeong; Jacek Kubica; Eliano P Navarese; Paul A Gurbel
Influence of genetic polymorphisms on platelet function, response to antiplatelet drugs and clinical outcomes in patients with coronary artery disease.
Expert review of cardiovascular therapy 2013;11(4):447-62.
2013: Joshua P Lewis; Braxton D Mitchell; Jeffrey R O'Connell; Ruth Pakzy; Afshin Parsa; Carl J Pepine; Toni I Pollin; Wendy S Post; Kathleen Ryan; Amber L Beitelshees; Kevin P Bliden; Coleen M Damcott; Nauder Faraday; Quince Gibson; Yan Gong; Paul A Gurbel; William Herzog; Richard B Horenstein; Julie A Johnson; Keith Tanner; Udaya S Tantry; Alan R Shuldiner
Genetic Variation in PEAR1 Is Associated With Platelet Aggregation and Cardiovascular Outcomes.
Circulation. Cardiovascular genetics 2013;6(2):184-92.
2013: Eliano Navarese; Karolina Obonska; Udaya Tantry; Felicita Andreotti; David Austin; Kevin Bliden; Antonino Buffon; Paul A Gurbel; Stefan James; Young-Hoon Jeong; Marek Kozinski; Jacek Kubica; Vijay Kunadian
Drug-coated balloons in treatment of in-stent restenosis: a meta-analysis of randomised controlled trials.
Clinical research in cardiology : official journal of the German Cardiac Society 2013;102(4):279-87.
2013: Eliano P Navarese; Gregg W Stone; Udaya Tantry; Felicita Andreotti; Diego Ardissino; Giuseppe Di Pasquale; Thomas Engstrøm; Paul A Gurbel; Young-Hoon Jeong; Elvin Kedhi; Waclaw Kochman; Marek Kozinski; Jacek Kubica
Optimal timing of coronary invasive strategy in non-ST-segment elevation acute coronary syndromes: a systematic review and meta-analysis.
Annals of internal medicine 2013;158(4):261-70.
2013: Paul A Gurbel; Young-Hoon Jeong; Alan R Shuldiner; Mark Antonino; Kevin P Bliden; Sumbul Chai; John G Fort; Martin Gesheff; Tania Gesheff; Ying Zhang; Udaya S Tantry
Spaced administration of PA32540 and clopidogrel results in greater platelet inhibition than synchronous administration of enteric-coated aspirin and enteric-coated omeprazole and clopidogrel.
American heart journal 2013;165(2):176-82.
2013: Jorge F Saucedo; Andrew L Frelinger; Dominick J Angiolillo; Timothy M Costigan; Roger DeRaad; Suman Duvvuru; Mark B Effron; Paul A Gurbel; Joseph A Jakubowski; Clement K Ojeh
Decrease in high on-treatment platelet reactivity (HPR) prevalence on switching from clopidogrel to prasugrel: insights from the switching anti-platelet (SWAP) study.
Thrombosis and haemostasis 2013;109(2):347-55.
2013: Udaya S Tantry; Paul A Gurbel
Antiplatelet drug resistance and variability in response: the role of antiplatelet therapy monitoring.
Current pharmaceutical design 2013;19(21):3795-815.
2013: Joshua P Lewis; Braxton D Mitchell; Jeffrey R O'Connell; Michael A Pacanowski; Cody J Peer; Kathleen Ryan; Kevin P Bliden; Sumbul Chai; William D Figg; Quince Gibson; Paul A Gurbel; Richard B Horenstein; Shawn D Spencer; Keith Tanner; Udaya S Tantry; Alan R Shuldiner
The functional G143E variant of carboxylesterase 1 is associated with increased clopidogrel active metabolite levels and greater clopidogrel response.
Pharmacogenetics and genomics 2013;23(1):1-8.
2013: Anand Singla; Udaya S Tantry; Young-Hoon Jeong; Denny P Mathew; William C Muse; Katrina Abadilla; Mark J Antonino; Oscar Bailon; Kevin P Bliden; Paul A Gurbel
Platelet reactivity and thrombogenicity in postmenopausal women.
Menopause (New York, N.Y.) 2013;20(1):57-63.
2013: Young-Hoon Jeong; Udaya S Tantry; Mark J Antonino; Kevin P Bliden; Paul A Gurbel
Usefulness of thrombelastography platelet mapping assay to measure the antiplatelet effect of P2Y(12) receptor inhibitors and high on-treatment platelet reactivity.
Platelets 2013;24(2):166-9.
2012: Paul A Gurbel; Kurt Huber; Joseph A Jakubowski; Benjamin Neely; Megan Neely; E Magnus Ohman; Dorairaj Prabhakaran; Matthew T Roe; Udaya S Tantry; Harvey D White; Chunmei Zhou; Paul W Armstrong; Eileen Brown; Mark Y Chan; Jan H Cornel; David Erlinge; Keith A A Fox; Shaun G Goodman
Platelet function during extended prasugrel and clopidogrel therapy for patients with ACS treated without revascularization: the TRILOGY ACS platelet function substudy.
JAMA : the journal of the American Medical Association 2012;308(17):1785-94.
2012: Young-Hoon Jeong; Sunjoo Kim; Eun-Ha Koh; Choong Hwan Kwak; Tae Jung Kwon; Jeong Rang Park; Yongwhi Park; Udaya S Tantry; Kevin P Bliden; Jin-Yong Hwang; Seok-Jae Hwang; Paul A Gurbel
Pharmacodynamic effect of cilostazol plus standard clopidogrel versus double-dose clopidogrel in patients with type 2 diabetes undergoing percutaneous coronary intervention.
Diabetes care 2012;35(11):2194-7.
2012: Matthew T Roe; Witold Ruzyllo; Gracita O Topacio; Chuen-Den Tseng; Harvey D White; Kenneth J Winters; Diego Ardissino; Paul W Armstrong; Philip E Aylward; Deepak L Bhatt; William E Boden; Eileen B Brown; Mircea Cinteză; Peter Clemmensen; Ramon Corbalan; Jan H Cornel; Anthony J Dalby; Keith A A Fox; Vladimir Gasparovic; Shaun G Goodman; Shmuel Gottlieb; Assen R Goudev; Paul A Gurbel; Christian Hamm; Judith S Hochman; Kurt Huber; Jose L Leiva-Pons; Yuliya Lokhnygina; Felipe Martinez; Darren K McGuire; R Craig McLendon; Bela Merkely; Jose C Nicolau; E Magnus Ohman; Ali Oto; Alexander Parkhomenko; Gregory Pavlides; Dorairaj Prabhakaran
Prasugrel versus clopidogrel for acute coronary syndromes without revascularization.
The New England journal of medicine 2012;367(14):1297-309.
2012: Eliano Navarese; Karolina Obonska; Adam Sukiennik; Udaya Tantry; Paul A Gurbel; Jacek Kubica
Caution in interpreting the findings from small observational studies.
International journal of cardiology 2012;160(1):71.
2012: Yongwhi Park; Udaya S Tantry; Jong Hwa Ahn; Kevin P Bliden; Eun-Ha Gho; Jin-Yong Hwang; Seok-Jae Hwang; Young-Hoon Jeong; Sunjoo Kim; Choong Hwan Kwak; Tae Jung Kwon; Jeong Rang Park; Paul A Gurbel
Accelerated platelet inhibition by switching from atorvastatin to a non-CYP3A4-metabolized statin in patients with high platelet reactivity (ACCEL-STATIN) study.
European heart journal 2012;33(17):2151-62.
2012: Young-Hoon Jeong; Yongwhi Park; Udaya S Tantry; Kevin P Bliden; Paul A Gurbel
Pharmacogenetic guidance for antiplatelet treatment.
Lancet 2012;380(9843):725; author reply 725-6.
2012: Mark J Antonino; Kevin P Bliden; Young-Hoon Jeong; Udaya S Tantry; Paul A Gurbel
Role of genotype-based personalized antiplatelet therapy in the era of potent P2Y₁₂ receptor inhibitors.
Expert review of cardiovascular therapy 2012;10(8):1011-22.
2012: Young-Hoon Jeong; Udaya S Tantry; Paul A Gurbel
Importance of potent P2Y(12) receptor blockade in acute myocardial infarction: focus on prasugrel.
Expert opinion on pharmacotherapy 2012;13(12):1771-96.
2012: Young-Hoon Jeong; Ki-Soo Park; Udaya S Tantry; Mark J Antonino; Kevin P Bliden; Paul A Gurbel
Usefulness of the VerifyNow P2Y12 assay to evaluate the antiplatelet effects of ticagrelor and clopidogrel therapies.
American heart journal 2012;164(1):35-42.
2012: Paul A Gurbel; Kurt Huber; Joseph A Jakubowski; Mark Y Chan; Jan H Cornel; David Erlinge; Shaun G Goodman; Matthew T Roe; Svathi Shah; Udaya S Tantry; E Magnus Ohman
Translational platelet research in patients with coronary artery disease: what are the major knowledge gaps?
Thrombosis and haemostasis 2012;108(1):12-20.
2012: Paul A Gurbel; Thomas D Nolin; Udaya S Tantry
Clopidogrel efficacy and cigarette smoking status.
JAMA : the journal of the American Medical Association 2012;307(23):2495-6.
2012: Robert C Welsh; Uwe Zeymer; Dominick J Angiolillo; Lisa G Berdan; Deepak L Bhatt; William J French; C Michael Gibson; Daniel D Gretler; Paul A Gurbel; Robert A Harrington; Kurt Huber; Janusz Kochman; Sergio Leonardi; Mina Madan; Matthew W McClure; Gayle Paynter; Sunil V Rao; Vivian P Thompson
A randomized, double-blind, active-controlled phase 2 trial to evaluate a novel selective and reversible intravenous and oral P2Y12 inhibitor elinogrel versus clopidogrel in patients undergoing nonurgent percutaneous coronary intervention: the INNOVATE-PCI trial.
Circulation. Cardiovascular interventions 2012;5(3):336-46.
2012: Dominick J Angiolillo; Samuel Broderick; Michael Buerke; Pamela B Conley; Marek Dabrowski; Paul A Gurbel; Robert A Harrington; Lisa K Jennings; Janusz Kochman; Matthew W McClure; Franz-Josef Neumann; Jorge F Saucedo; Gillian Stephens; Juergen Stumpf; Dietmar Trenk; Robert C Welsh; Jarosław Wójcik; Sunil V Rao
Pharmacokinetic and pharmacodynamic effects of elinogrel: results of the platelet function substudy from the intravenous and oral administration of elinogrel to evaluate tolerability and efficacy in nonurgent percutaneous coronary intervention patients (INNOVATE-PCI) trial.
Circulation. Cardiovascular interventions 2012;5(3):347-56.
2012: Steen E Husted; Robert F Storey; Udaya S Tantry; Renli Teng; Cheryl Wei; Kevin Bliden; Kathleen Butler; Lene Høimark; Paul A Gurbel
Pharmacokinetics and pharmacodynamics of ticagrelor in patients with stable coronary artery disease: results from the ONSET-OFFSET and RESPOND studies.
Clinical pharmacokinetics 2012;51(6):397-409.
2012: Paul A Gurbel; Young-Hoon Jeong; E Magnus Ohman; Udaya S Tantry
Toward a therapeutic window for antiplatelet therapy in the elderly.
European heart journal 2012;33(10):1187-9.
2012: Eliano Pio Navarese; Luigi Tavazzi; Felicita Andreotti; Antonino Buffon; Alberto Cremonesi; Paul A Gurbel; Marek Kozinski; Aldona Kubica; Jacek Kubica; Giuseppe Musumeci; Fausto Castriota
Adenosine improves post-procedural coronary flow but not clinical outcomes in patients with acute coronary syndrome: a meta-analysis of randomized trials.
Atherosclerosis 2012;222(1):1-7.
2012: Elisabeth Mahla; Helfried Metzler; Peter Rehak; Jeffery Sell; Alejandro J Sequeira; Thomas A Suarez; Udaya S Tantry; Mark J Antonino; Kevin P Bliden; Peter Cho; John Fan; Paul A Gurbel
Platelet function measurement-based strategy to reduce bleeding and waiting time in clopidogrel-treated patients undergoing coronary artery bypass graft surgery: the timing based on platelet function strategy to reduce clopidogrel-associated bleeding related to CABG (TARGET-CABG) study.
Circulation. Cardiovascular interventions 2012;5(2):261-9.
2012: Paul A Gurbel; Udaya S Tantry
Do platelet function testing and genotyping improve outcome in patients treated with antithrombotic agents?: platelet function testing and genotyping improve outcome in patients treated with antithrombotic agents.
Circulation 2012;125(10):1276-87; discussion 1287.
2012: Udaya S Tantry; Young-Hoon Jeong; Eliano P Navarese; Paul A Gurbel
Platelet function measurement in elective percutaneous coronary intervention patients: exploring the concept of a P2Y₁₂ inhibitor therapeutic window.
JACC. Cardiovascular interventions 2012;5(3):290-2.
2012: Young-Hoon Jeong; Udaya S Tantry; Kevin P Bliden; Paul A Gurbel
High on-treatment platelet reactivity assessed by various platelet function tests: is the consensus-defined cut-off of VASP-P platelet reactivity index too low?
Journal of thrombosis and haemostasis : JTH 2012;10(3):487-9.
2012: Young-Hoon Jeong; Yongwhi Park; Udaya S Tantry; Kevin P Bliden; Paul A Gurbel
High platelet reactivity to multiple agonists during aspirin and clopidogrel treatment is indicative of a global hyperreactive platelet phenotype.
Heart (British Cardiac Society) 2012;98(4):343; author reply 343-4.
2012: Udaya S Tantry; Andrzej Budaj; Paul A Gurbel
Antiplatelet therapy beyond 2012: role of personalized medicine.
Polskie Archiwum Medycyny Wewnętrznej 2012;122(6):298-305.
2012: Jacek Kubica; Eliano P Navarese; Udaya S Tantry; Iwona Świątkiewicz; Kevin P Bliden; Tomasz Fabiszak; Grzegorz Grześk; Marek Koziński; Aldona Kubica; Paul A Gurbel
Updated evidence on intracoronary abciximab in ST-elevation myocardial infarction: a systematic review and meta-analysis of randomized clinical trials.
Cardiology journal 2012;19(3):230-42.
2012: Eliano Navarese; Karolina Obonska; Paul A Gurbel; Marek Kozinski; Jacek Kubica; Massimo Margheri; Giuseppe De Luca
Clinical efficacy and safety of intracoronary vs. intravenous abciximab administration in STEMI patients undergoing primary percutaneous coronary intervention: a meta-analysis of randomized trials.
Platelets 2012;23(4):274-81.
2012: Paul A Gurbel; Tania Gesheff; WILLIAM HERZOG; Benjamin V Dubois; Mark J Antonino; Kevin P Bliden; Charles C Cummings; Udaya S Tantry
Time dependence of clopidogrel loading effect: platelet activation versus platelet aggregation.
Thrombosis research 2012;129(1):1-2.
2011: Young-Hoon Jeong; Udaya S Tantry; Kevin P Bliden; Paul A Gurbel
The role of platelet function testing and genotyping in the stented patient treated with clopidogrel.
Journal of the American College of Cardiology 2011;58(25):2701-2; author reply 2702.
2011: Paul A Gurbel; J R Plachetka; Y Zhang; M Antonino; Kevin P Bliden; J Fort; M Gesheff; Udaya S Tantry
Pharmacodynamic evaluation of clopidogrel plus PA32540: the Spaced PA32540 With Clopidogrel Interaction Gauging (SPACING) study.
Clinical pharmacology and therapeutics 2011;90(6):860-6.
2011: Young-Hoon Jeong; Seok-Jae Hwang; Udaya S Tantry; Yongwhi Park; In-Suk Kim; Choong Hwan Kwak; Kevin P Bliden; Tae Jung Kwon; Jin-Yong Hwang; Jin-Sin Koh; Paul A Gurbel
Effect of CYP2C19*2 and *3 loss-of-function alleles on platelet reactivity and adverse clinical events in East Asian acute myocardial infarction survivors treated with clopidogrel and aspirin.
Circulation. Cardiovascular interventions 2011;4(6):585-94.
2011: Eliano Pio Navarese; Jacek Kubica; Paul A Gurbel
"Sirolimus or paclitaxel drug eluting stent in left main disease: the winner is... ".
International journal of cardiology 2011;152(3):387.
2011: J P Lewis; Braxton D Mitchell; Jeffrey R O'Connell; R Pakzy; K Ryan; Haiqing Shen; Kevin P Bliden; A S Fisch; Q Gibson; Paul A Gurbel; Richard B Horenstein; K Tanner; Udaya S Tantry; Alan R Shuldiner
Paraoxonase 1 (PON1) gene variants are not associated with clopidogrel response.
Clinical pharmacology and therapeutics 2011;90(4):568-74.
2011: Paul A Gurbel; Young-Hoon Jeong; Udaya S Tantry
Vorapaxar: a novel protease-activated receptor-1 inhibitor.
Expert opinion on investigational drugs 2011;20(10):1445-53.
2011: Eliano Navarese; Jolanta Siller-Matula; Adam Sukiennik; Felicita Andreotti; Antonino Buffon; F Castriota; G De Luca; S De Servi; C M Gibson; Paul A Gurbel; Marek Kozinski; Jacek Kubica
Low-molecular-weight heparins vs. unfractionated heparin in the setting of percutaneous coronary intervention for ST-elevation myocardial infarction: a meta-analysis.
Journal of thrombosis and haemostasis : JTH 2011;9(10):1902-15.
2011: Udaya S Tantry; Paul A Gurbel
Assessment of oral antithrombotic therapy by platelet function testing.
Nature reviews. Cardiology 2011;8(10):572-9.
2011: Paul A Gurbel; Young-Hoon Jeong; Udaya S Tantry
Cutaneous clopidogrel hypersensitivity: give steroids and do not stop the clopidogrel.
Journal of the American College of Cardiology 2011;58(14):1455-6.
2011: R F Storey; U Tantry; C Wei; A Karunakaran; Kevin P Bliden; K Butler; R Ecob; Paul A Gurbel
Earlier recovery of platelet function after discontinuation of treatment with ticagrelor compared with clopidogrel in patients with high antiplatelet responses.
Journal of thrombosis and haemostasis : JTH 2011;9(9):1730-7.
2011: Paul A Gurbel; Udaya S Tantry
Clopidogrel response variability and the advent of personalised antiplatelet therapy. A bench to bedside journey.
Thrombosis and haemostasis 2011;106(2):265-71.
2011: Paul A Gurbel; Kevin P Bliden; Udaya S Tantry; Young-Hoon Jeong
Immunity to thrombotic events is achievable if we stop the guessing game: is this the major hidden message from GRAVITAS?
Thrombosis and haemostasis 2011;106(2):263-4.
2011: Paul A Gurbel; Elisabeth Mahla; Udaya S Tantry
Peri-operative platelet function testing: the potential for reducing ischaemic and bleeding risks.
Thrombosis and haemostasis 2011;106(2):248-52.
2011: Young-Hoon Jeong; In-Suk Kim; Yongwhi Park; Udaya S Tantry; Kevin P Bliden; Paul A Gurbel
We need further studies for the development of "optimized antiplatelet therapy" based on ethnicity.
Journal of the American College of Cardiology 2011;58(2):198; author reply 198-9.
2011: Kevin P Bliden; Martin Gesheff; Young-Hoon Jeong; Robert F Storey; Udaya S Tantry; Cheryl Wei; Paul A Gurbel
The effect of ticagrelor versus clopidogrel on high on-treatment platelet reactivity: combined analysis of the ONSET/OFFSET and RESPOND studies.
American heart journal 2011;162(1):160-5.
2011: Young-Hoon Jeong; Udaya S Tantry; Kevin P Bliden; Paul A Gurbel
Do East Asians have different hypercoagulable states compared with Western population?
American heart journal 2011;162(1):e19-20; author reply e21-2.
2011: David E Kandzari; Laura Mauri; Jeffrey J Popma; Mark A Turco; Paul A Gurbel; Peter J Fitzgerald; Martin B Leon
Late-term clinical outcomes with zotarolimus- and sirolimus-eluting stents. 5-year follow-up of the ENDEAVOR III (A Randomized Controlled Trial of the Medtronic Endeavor Drug [ABT-578] Eluting Coronary Stent System Versus the Cypher Sirolimus-Eluting Coronary Stent System in De Novo Native Coronary Artery Lesions).
JACC. Cardiovascular interventions 2011;4(5):543-50.
2011: Udaya S Tantry; Dean J Kereiakes; Paul A Gurbel
Clopidogrel and proton pump inhibitors: influence of pharmacological interactions on clinical outcomes and mechanistic explanations.
JACC. Cardiovascular interventions 2011;4(4):365-80.
2011: Kevin P Bliden; Udaya S Tantry; Joseph DiChiara; Paul A Gurbel
Further ex vivo evidence supporting higher aspirin dosing in patients with coronary artery disease and diabetes.
Circulation. Cardiovascular interventions 2011;4(2):118-20.
2011: Paul A Gurbel; Udaya S Tantry
An initial experiment with personalized antiplatelet therapy: the GRAVITAS trial.
JAMA : the journal of the American Medical Association 2011;305(11):1136-7.
2011: Paul A Gurbel; Alan R Shuldiner; Kevin P Bliden; Kathaleen Ryan; Ruth E Pakyz; Udaya S Tantry
The relation between CYP2C19 genotype and phenotype in stented patients on maintenance dual antiplatelet therapy.
American heart journal 2011;161(3):598-604.
2011: Udaya S Tantry; Paul A Gurbel
Current options in oral antiplatelet strategies during percutaneous coronary interventions.
Reviews in cardiovascular medicine 2011;12 Suppl 1():S4-13.
2011: Young-Hoon Jeong; Udaya S Tantry; Kevin P Bliden; Paul A Gurbel
Cilostazol to overcome high on-treatment platelet reactivity in korean patients treated with clopidogrel and calcium-channel blocker.
Circulation journal : official journal of the Japanese Circulation Society 2011;75(11):2534-6.
2011: Matthew J Price; Udaya S Tantry; Paul A Gurbel
The influence of CYP2C19 polymorphisms on the pharmacokinetics, pharmacodynamics, and clinical effectiveness of P2Y(12) inhibitors.
Reviews in cardiovascular medicine 2011;12(1):1-12.
2011: Paul A Gurbel; Udaya S Tantry
Antiplatelet therapy: Clopidogrel-PPI interaction, an ongoing controversy.
Nature reviews. Cardiology 2011;8(1):7-8.
2011: Wei C Lau; Terrence D Welch; Theresa Shields; Melvyn Rubenfire; Udaya S Tantry; Paul A Gurbel
The effect of St John's Wort on the pharmacodynamic response of clopidogrel in hyporesponsive volunteers and patients: increased platelet inhibition by enhancement of CYP3A4 metabolic activity.
Journal of cardiovascular pharmacology 2011;57(1):86-93.
2010: Udaya S Tantry; Kevin P Bliden; Cheryl Wei; Robert F Storey; Martin Armstrong; Kathleen Butler; Paul A Gurbel
First analysis of the relation between CYP2C19 genotype and pharmacodynamics in patients treated with ticagrelor versus clopidogrel: the ONSET/OFFSET and RESPOND genotype studies.
Circulation. Cardiovascular genetics 2010;3(6):556-66.
2010: Mark J Antonino; Rosa Coppolecchia; Elisabeth Mahla; Kevin P Bliden; Udaya S Tantry; Paul A Gurbel
Antiplatelet effects of aspirin with phytosterols: comparison with non-enteric coated aspirin alone.
Thrombosis research 2010;126(5):384-5.
2010: Jessica L Mega; Tabassome Simon; Jean-Philippe Collet; Jeffrey L Anderson; Elliott M Antman; Kevin Bliden; Christopher P Cannon; Nicolas Danchin; Betti Giusti; Paul A Gurbel; Benjamin D Horne; Jean-Sebastian Hulot; Adnan Kastrati; Gilles Montalescot; Franz-Josef Neumann; Lei Shen; Dirk Sibbing; P Gabriel Steg; Dietmar Trenk; Stephen D Wiviott; Marc S Sabatine
Reduced-function CYP2C19 genotype and risk of adverse clinical outcomes among patients treated with clopidogrel predominantly for PCI: a meta-analysis.
JAMA : the journal of the American Medical Association 2010;304(16):1821-30.
2010: Paul A Gurbel; Udaya S Tantry; Alan R Shuldiner
Letter by Gurbel et al regarding article, "Cytochrome 2C19*17 allelic variant, platelet aggregation, bleeding events, and stent thrombosis in clopidogrel-treated patients with coronary stent placement".
Circulation 2010;122(14):e478; author reply e479.
2010: Paul A Gurbel; Udaya S Tantry
Acceptance of high platelet reactivity as a risk factor: now, what do we do about it?
JACC. Cardiovascular interventions 2010;3(10):1008-10.
2010: Dominick J Angiolillo; Jorge F Saucedo; Roger Deraad; Andrew L Frelinger; Paul A Gurbel; Timothy M Costigan; Joseph A Jakubowski; Clement K Ojeh; Mark B Effron
Increased platelet inhibition after switching from maintenance clopidogrel to prasugrel in patients with acute coronary syndromes: results of the SWAP (SWitching Anti Platelet) study.
Journal of the American College of Cardiology 2010;56(13):1017-23.
2010: Laurent Bonello; Udaya S Tantry; Rossella Marcucci; Ruediger Blindt; Dominick J Angiolillo; Richard Becker; Deepak L Bhatt; Marco Cattaneo; Jean Philippe Collet; Thomas Cuisset; Christian Gachet; Gilles Montalescot; Lisa K Jennings; Dean Kereiakes; Dirk Sibbing; Dietmar Trenk; Jochem W van Werkum; Franck Paganelli; Matthew J Price; Ron Waksman; Paul A Gurbel
Consensus and future directions on the definition of high on-treatment platelet reactivity to adenosine diphosphate.
Journal of the American College of Cardiology 2010;56(12):919-33.
2010: Elisabeth Mahla; Helfried Metzler; Udaya S Tantry; Paul A Gurbel
Controversies in oral antiplatelet therapy in patients undergoing aortocoronary bypass surgery.
The Annals of thoracic surgery 2010;90(3):1040-51.
2010: Paul A Gurbel; Dean J Kereiakes; Udaya S Tantry
Ticagrelor for the treatment of arterial thrombosis.
Expert opinion on pharmacotherapy 2010;11(13):2251-9.
2010: Paul A Gurbel; Kevin P Bliden; Irene A Navickas; Elizabeth Mahla; Joseph DiChiara; Thomas A Suarez; Mark J Antonino; Udaya S Tantry; Eli Cohen
Adenosine diphosphate-induced platelet-fibrin clot strength: a new thrombelastographic indicator of long-term poststenting ischemic events.
American heart journal 2010;160(2):346-54.
2010: Robert F Storey; Kevin P Bliden; Shankar B Patil; Arun Karunakaran; Rosemary Ecob; Kathleen Butler; Renli Teng; Cheryl Wei; Udaya S Tantry; Paul A Gurbel
Incidence of dyspnea and assessment of cardiac and pulmonary function in patients with stable coronary artery disease receiving ticagrelor, clopidogrel, or placebo in the ONSET/OFFSET study.
Journal of the American College of Cardiology 2010;56(3):185-93.
2010: Paul A Gurbel; Udaya S Tantry; Alan R Shuldiner; Dean J Kereiakes
Genotyping: one piece of the puzzle to personalize antiplatelet therapy.
Journal of the American College of Cardiology 2010;56(2):112-6.
2010: Charles H Hennekens; Wendy R Schneider; Patricia R Hebert; Udaya S Tantry; Paul A Gurbel
Hypothesis formulation from subgroup analyses: nonadherence or nonsteroidal anti-inflammatory drug use explains the lack of clinical benefit of aspirin on first myocardial infarction attributed to "aspirin resistance".
American heart journal 2010;159(5):744-8.
2010: Paul A Gurbel; Kevin P Bliden; Kathleen Butler; Mark J Antonino; Cheryl Wei; Renli Teng; Lars Rasmussen; Robert F Storey; Tonny Nielsen; John W Eikelboom; Georges Sabe-Affaki; Steen Husted; Dean J Kereiakes; David Henderson; Dharmendra V Patel; Udaya S Tantry
Response to ticagrelor in clopidogrel nonresponders and responders and effect of switching therapies: the RESPOND study.
Circulation 2010;121(10):1188-99.
2010: Richard C Becker; Paul A Gurbel
Platelet P2Y12 receptor antagonist pharmacokinetics and pharmacodynamics: A foundation for distinguishing mechanisms of bleeding and anticipated risk for platelet-directed therapies.
Thrombosis and haemostasis 2010;103(3):535-44.
2010: Paul A Gurbel; Udaya S Tantry
Delivery of glycoprotein IIb/IIIa inhibitor therapy for percutaneous coronary intervention: why not take the intracoronary highway?
Circulation 2010;121(6):739-41.
2010: Paul A Gurbel; Udaya S Tantry
Combination antithrombotic therapies.
Circulation 2010;121(4):569-83.
2010: Paul A Gurbel; Udaya S Tantry; Dean J Kereiakes
Interaction between clopidogrel and proton-pump inhibitors and management strategies in patients with cardiovascular diseases.
Drug, healthcare and patient safety 2010;2():233-40.
2010: Udaya S Tantry; Kevin P Bliden; Thomas A Suarez; Rolf P Kreutz; Joseph DiChiara; Paul A Gurbel
Hypercoagulability, platelet function, inflammation and coronary artery disease acuity: results of the Thrombotic RIsk Progression (TRIP) study.
Platelets 2010;21(5):360-7.
2010: Paul A Gurbel; Kevin P Bliden; M J Antonino; G Stephens; D D Gretler; M M Jurek; R E Pakyz; Alan R Shuldiner; P B Conley; Udaya S Tantry
The effect of elinogrel on high platelet reactivity during dual antiplatelet therapy and the relation to CYP2C19*2 genotype: first experience in patients.
Journal of thrombosis and haemostasis : JTH 2010;8(1):43-53.
2009: Paul A Gurbel; Kevin P Bliden; Kathleen Butler; Udaya S Tantry; Tania Gesheff; Cheryl Wei; Renli Teng; Mark J Antonino; Shankar B Patil; Arun Karunakaran; Dean J Kereiakes; Cordel Parris; Drew Purdy; Vance Wilson; Gary S Ledley; Robert F Storey
Randomized double-blind assessment of the ONSET and OFFSET of the antiplatelet effects of ticagrelor versus clopidogrel in patients with stable coronary artery disease: the ONSET/OFFSET study.
Circulation 2009;120(25):2577-85.
2009: Paul A Gurbel; Udaya S Tantry; Alan R Shuldiner
The worry about clopidogrel "nonresponsiveness": identification and treatment in the post-percutaneous coronary intervention patient.
JACC. Cardiovascular interventions 2009;2(11):1102-4.
2009: U S Tantry; Paul A Gurbel
Platelet monitoring for PCI: is it really necessary?
Hämostaseologie 2009;29(4):368-75.
2009: Anand Singla; Mark J Antonino; Kevin P Bliden; Udaya S Tantry; Paul A Gurbel
The relation between platelet reactivity and glycemic control in diabetic patients with cardiovascular disease on maintenance aspirin and clopidogrel therapy.
American heart journal 2009;158(5):784.e1-6.
2009: Udaya S Tantry; Elisabeth Mahla; Paul A Gurbel
Aspirin resistance.
Progress in cardiovascular diseases 2009;52(2):141-52.
2009: Alan R Shuldiner; Jeffrey R O'Connell; Kevin P Bliden; Amish Gandhi; Kathleen Ryan; Richard B Horenstein; Coleen M Damcott; Ruth Pakyz; Udaya S Tantry; Quince Gibson; Toni I Pollin; Wendy S Post; Afshin Parsa; Braxton D Mitchell; Nauder Faraday; WILLIAM HERZOG; Paul A Gurbel
Association of cytochrome P450 2C19 genotype with the antiplatelet effect and clinical efficacy of clopidogrel therapy.
JAMA : the journal of the American Medical Association 2009;302(8):849-57.
2009: Tina L Pinto Slottow; Laurent Bonello; Rekha Gavini; Patricia Beauzile; Steven J Sushinsky; Mickey Scheinowitz; Kimberly Kaneshige; Zhenyi Xue; Rebecca Torguson; Udaya Tantry; Augusto D Pichard; Lowell F Satler; William O Suddath; Kenneth Kent; Paul A Gurbel; Ron Waksman
Prevalence of aspirin and clopidogrel resistance among patients with and without drug-eluting stent thrombosis.
The American journal of cardiology 2009;104(4):525-30.
2009: Paul A Gurbel; Mark J Antonino; Udaya S Tantry
Recent developments in clopidogrel pharmacology and their relation to clinical outcomes.
Expert opinion on drug metabolism & toxicology 2009;5(8):989-1004.
2009: James Hoekstra; Marc Cohen; Robert Giugliano; Christopher B Granger; Paul A Gurbel; Judd E Hollander; Steven V Manoukian; Jorge F Saucedo; Charles V Pollack
Expert consensus on treatment strategies in non- ST-segment elevation acute coronary syndromes in patients undergoing percutaneous coronary intervention--an evidence-based review of clinical trial results and treatment guidelines from an emergency medicine perspective: report on a roundtable discussion.
The American journal of emergency medicine 2009;27(6):720-8.
2009: Mark J Antonino; Elisabeth Mahla; Kevin P Bliden; Udaya S Tantry; Paul A Gurbel
Effect of long-term clopidogrel treatment on platelet function and inflammation in patients undergoing coronary arterial stenting.
The American journal of cardiology 2009;103(11):1546-50.
2009: Paul A Gurbel; Elisabeth Mahla; Mark J Antonino; Udaya S Tantry
Response variability and the role of platelet function testing.
The Journal of invasive cardiology 2009;21(4):172-8.
2009: Wei C Lau; Paul A Gurbel
The drug-drug interaction between proton pump inhibitors and clopidogrel.
CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 2009;180(7):699-700.
2009: Elisabeth Mahla; Mark J Antonino; Udaya S Tantry; Paul A Gurbel
Point-of-care platelet function analysis ready for prime time?
Journal of the American College of Cardiology 2009;53(10):857-9.
2009: Paul A Gurbel; Kevin P Bliden; Rolf P Kreutz; Joseph DiChiara; Mark J Antonino; Udaya S Tantry
The link between heightened thrombogenicity and inflammation: pre-procedure characterization of the patient at high risk for recurrent events after stenting.
Platelets 2009;20(2):97-104.
2009: John R Gilstad; Paul A Gurbel; Ross E Andersen
Relationship between age and platelet activation in patients with stable and unstable angina.
Archives of gerontology and geriatrics 2009;48(2):155-9.
2009: Paul A Gurbel; Kevin P Bliden; Jorge F Saucedo; Thomas A Suarez; Joseph DiChiara; Mark J Antonino; Elisabeth Mahla; Anand Singla; WILLIAM HERZOG; Ashwani K Bassi; Thomas A Hennebry; Tania B Gesheff; Udaya S Tantry
Bivalirudin and clopidogrel with and without eptifibatide for elective stenting: effects on platelet function, thrombelastographic indexes, and their relation to periprocedural infarction results of the CLEAR PLATELETS-2 (Clopidogrel with Eptifibatide to Arrest the Reactivity of Platelets) study.
Journal of the American College of Cardiology 2009;53(8):648-57.
2009: Dominick J Angiolillo; Deepak L Bhatt; Paul A Gurbel; Lisa K Jennings
Advances in antiplatelet therapy: agents in clinical development.
The American journal of cardiology 2009;103(3 Suppl):40A-51A.
2009: Paul A Gurbel; Udaya S Tantry
Selecting optimal antiplatelet therapy based on platelet function monitoring in patients with coronary artery disease.
Current treatment options in cardiovascular medicine 2009;11(1):22-32.
2009: Paul A Gurbel; Udaya S Tantry
Antiplatelet resistance--fact or myth?
The American heart hospital journal 2009;7(1):50-7.
2008: Paul A Gurbel; Udaya S Tantry
The rationale for and comparisons of different antiplatelet treatments in acute coronary syndrome.
Journal of interventional cardiology 2008;21 Suppl 1():S10-7.
2008: Paul A Gurbel; Mark J Antonino; Kevin P Bliden; Joseph Dichiara; Thomas A Suarez; Anand Singla; Udaya S Tantry
Platelet reactivity to adenosine diphosphate and long-term ischemic event occurrence following percutaneous coronary intervention: a potential antiplatelet therapeutic target.
Platelets 2008;19(8):595-604.
2008: Miruais S Hamed; Steven Gambert; Kevin P Bliden; Oscar Bailon; Anand Singla; Singla Anand; Mark J Antonino; Fatema Hamed; Udaya S Tantry; Paul A Gurbel
Dark chocolate effect on platelet activity, C-reactive protein and lipid profile: a pilot study.
Southern medical journal 2008;101(12):1203-8.
2008: Kevin P Bliden; Joseph DiChiara; Lookman Lawal; Anand Singla; Mark J Antonino; Brian A Baker; William L Bailey; Udaya S Tantry; Paul A Gurbel
The association of cigarette smoking with enhanced platelet inhibition by clopidogrel.
Journal of the American College of Cardiology 2008;52(7):531-3.
2008: Marc Cohen; James Hoekstra; Robert Giugliano; Christopher B Granger; Paul A Gurbel; Judd E Hollander; Steven V Manoukian; Charles V Pollack; Jorge F Saucedo
Treatment strategies in non-ST-elevation acute coronary syndromes in patients undergoing percutaneous coronary intervention: an evidence-based review of clinical trial results and treatment guidelines: report on a roundtable discussion.
Journal of interventional cardiology 2008;21(4):283-99.
2008: Paul A Gurbel; Kevin P Bliden; Eli Cohen; Irene A Navickas; Anand Singla; Mark J Antonino; Mulugeta Fissha; Rolf P Kreutz; Ashwani K Bassi; Udaya S Tantry
Race and sex differences in thrombogenicity: risk of ischemic events following coronary stenting.
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 2008;19(4):268-75.
2008: Paul A Gurbel; Mark J Antonino; Udaya S Tantry
Antiplatelet treatment of cardiovascular disease: a translational research perspective.
Polskie Archiwum Medycyny Wewnętrznej 2008;118(5):289-97.
2008: Dean J Kereiakes; Paul A Gurbel
Peri-procedural platelet function and platelet inhibition in percutaneous coronary intervention.
JACC. Cardiovascular interventions 2008;1(2):111-21.
2008: Eugene Braunwald; Dominick Angiolillo; Eric R Bates; Peter B Berger; Deepak Bhatt; Christopher P Cannon; Mark I Furman; Paul A Gurbel; Alan D Michelson; Eric Peterson; Stephen Wiviott
Antiplatelet therapy and platelet function testing.
Clinical cardiology 2008;31(3 Suppl 1):I36.
2008: Eugene Braunwald; Dominick Angiolillo; Eric R Bates; Peter B Berger; Deepak Bhatt; Christopher P Cannon; Mark I Furman; Paul A Gurbel; Alan D Michelson; Eric Peterson; Stephen Wiviott
Clinical considerations with the use of antiplatelet therapy in patients undergoing percutaneous coronary intervention.
Clinical cardiology 2008;31(3 Suppl 1):I28-35.
2008: Eugene Braunwald; Dominick Angiolillo; Eric R Bates; Peter B Berger; Deepak Bhatt; Christopher P Cannon; Mark I Furman; Paul A Gurbel; Alan D Michelson; Eric Peterson; Stephen Wiviott
Investigating the mechanisms of hyporesponse to antiplatelet approaches.
Clinical cardiology 2008;31(3 Suppl 1):I21-7.
2008: Eugene Braunwald; Dominick Angiolillo; Eric R Bates; Peter B Berger; Deepak Bhatt; Christopher P Cannon; Mark I Furman; Paul A Gurbel; Alan D Michelson; Eric Peterson; Stephen Wiviott
Antiplatelet strategies: evaluating their current role in the setting of acute coronary syndromes.
Clinical cardiology 2008;31(3 Suppl 1):I2-9.
2008: Eugene Braunwald; Dominick Angiolillo; Eric R Bates; Peter B Berger; Deepak Bhatt; Christopher P Cannon; Mark I Furman; Paul A Gurbel; Alan D Michelson; Eric Peterson; Stephen Wiviott
The problem of persistent platelet activation in acute coronary syndromes and following percutaneous coronary intervention.
Clinical cardiology 2008;31(3 Suppl 1):I17-20.
2008: Eugene Braunwald; Dominick Angiolillo; Eric R Bates; Peter B Berger; Deepak Bhatt; Christopher P Cannon; Mark I Furman; Paul A Gurbel; Alan D Michelson; Eric Peterson; Stephen Wiviott
Assessing the current role of platelet function testing.
Clinical cardiology 2008;31(3 Suppl 1):I10-6.
2008: Eugene Braunwald; Dominick Angiolillo; Eric R Bates; Peter B Berger; Deepak Bhatt; Christopher P Cannon; Mark I Furman; Paul A Gurbel; Alan D Michelson; Eric Peterson; Stephen Wiviott
Antiplatelet therapy and platelet function testing. Introduction.
Clinical cardiology 2008;31(3 Suppl 1):I1.
2008: Paul A Gurbel; Udaya S Tantry
Prasugrel, a third generation thienopyridine and potent platelet inhibitor.
Current opinion in investigational drugs (London, England : 2000) 2008;9(3):324-36.
2008: Paul A Gurbel; Wei C Lau; Udaya S Tantry
Omeprazole: a possible new candidate influencing the antiplatelet effect of clopidogrel.
Journal of the American College of Cardiology 2008;51(3):261-3.
2008: Paul A Gurbel; Kevin P Bilden; Udaya S Tantry
Diagnostics for aspirin resistance.
Molecular diagnosis & therapy 2008;12(1):55-6.
2008: Paul A Gurbel; Rolf P Kreutz; Kevin P Bliden; Joseph DiChiara; Udaya S Tantry
Biomarker analysis by fluorokine multianalyte profiling distinguishes patients requiring intervention from patients with long-term quiescent coronary artery disease: a potential approach to identify atherosclerotic disease progression.
American heart journal 2008;155(1):56-61.
2007: Rolf P Kreutz; Udaya S Tantry; Kevin P Bliden; Paul A Gurbel
Inflammatory changes during the 'common cold' are associated with platelet activation and increased reactivity of platelets to agonists.
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 2007;18(8):713-8.
2007: Joseph DiChiara; Kevin P Bliden; Udaya S Tantry; Miruais S Hamed; Mark J Antonino; Thomas A Suarez; Oscar Bailon; Anand Singla; Paul A Gurbel
The effect of aspirin dosing on platelet function in diabetic and nondiabetic patients: an analysis from the aspirin-induced platelet effect (ASPECT) study.
Diabetes 2007;56(12):3014-9.
2007: Robert F Storey; Steen Husted; Robert A Harrington; Stan Heptinstall; Robert G Wilcox; Gary Peters; Mark Wickens; Håkan Emanuelsson; Paul A Gurbel; Peer Grande; Christopher P Cannon
Inhibition of platelet aggregation by AZD6140, a reversible oral P2Y12 receptor antagonist, compared with clopidogrel in patients with acute coronary syndromes.
Journal of the American College of Cardiology 2007;50(19):1852-6.
2007: Paul A Gurbel; Richard C Becker; Kenneth G Mann; Steven R Steinhubl; Alan D Michelson
Platelet function monitoring in patients with coronary artery disease.
Journal of the American College of Cardiology 2007;50(19):1822-34.
2007: Paul A Gurbel; Kevin P Bliden; I Navickas; E Cohen; Udaya S Tantry
Post-coronary intervention recurrent ischemia in the presence of adequate platelet inhibition by dual antiplatelet therapy: what are we overlooking?
Journal of thrombosis and haemostasis : JTH 2007;5(11):2300-1.
2007: Paul A Gurbel; Joseph DiChiara; Udaya S Tantry
Antiplatelet therapy after implantation of drug-eluting stents: duration, resistance, alternatives, and management of surgical patients.
The American journal of cardiology 2007;100(8B):18M-25M.
2007: Joseph DiChiara; Kevin P Bliden; Udaya S Tantry; Srivasavi K Chaganti; Rolf P Kreutz; Tania B Gesheff; Yvonne Kreutz; Paul A Gurbel
Platelet function measured by VerifyNow identifies generalized high platelet reactivity in aspirin treated patients.
Platelets 2007;18(6):414-23.
2007: Paul A Gurbel; Kevin P Bliden; Joseph DiChiara; Justin Newcomer; Willy Weng; Nagaraj K Neerchal; Tania Gesheff; Srivasavi K Chaganti; Amena Etherington; Udaya S Tantry
Evaluation of dose-related effects of aspirin on platelet function: results from the Aspirin-Induced Platelet Effect (ASPECT) study.
Circulation 2007;115(25):3156-64.
2007: Paul A Gurbel; Udaya S Tantry
[The role of clopidogrel in cardiovascular diseases].
Polskie Archiwum Medycyny Wewnętrznej 2007;117(5-6):207-9.
2007: Paul A Gurbel; Kevin P Bliden; Udaya S Tantry
Evidence that pre-existent variability in platelet response to ADP accounts for 'clopidogrel resistance': a rebuttal.
Journal of thrombosis and haemostasis : JTH 2007;5(5):1087-8; author reply 1089-90.
2007: Kevin P Bliden; Joseph DiChiara; Udaya S Tantry; Ashwani K Bassi; Srivasavi K Chaganti; Paul A Gurbel
Increased risk in patients with high platelet aggregation receiving chronic clopidogrel therapy undergoing percutaneous coronary intervention: is the current antiplatelet therapy adequate?
Journal of the American College of Cardiology 2007;49(6):657-66.
2007: Udaya S Tantry; Kevin P Bliden; Paul A Gurbel
AZD6140.
Expert opinion on investigational drugs 2007;16(2):225-9.
2007: Paul A Gurbel; D E Kandzari
Stent thrombosis associated with first-generation drug-eluting stents: issues with antiplatelet therapy.
Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation 2007;15(4):148-50.
2007: Paul A Gurbel; Udaya S Tantry
Stent thrombosis: role of compliance and nonresponsiveness to antiplatelet therapy.
Reviews in cardiovascular medicine 2007;8 Suppl 1():S19-26.
2007: Paul A Gurbel; Kevin P Bliden; Amena Etherington; Udaya S Tantry
Assessment of clopidogrel responsiveness: measurements of maximum platelet aggregation, final platelet aggregation and their correlation with vasodilator-stimulated phosphoprotein in resistant patients.
Thrombosis research 2007;121(1):107-15.
2007: Paul A Gurbel; Udaya S Tantry
Clopidogrel resistance?
Thrombosis research 2007;120(3):311-21.
2007: Paul A Gurbel; Kevin P Bliden; Kirk Guyer; Nikhil Aggarwal; Udaya S Tantry
Delayed thrombin-induced platelet-fibrin clot generation by clopidogrel: a new dose-related effect demonstrated by thrombelastography in patients undergoing coronary artery stenting.
Thrombosis research 2007;119(5):563-70.
2006: David E Kandzari; Martin B Leon; Jeffrey J Popma; Peter J Fitzgerald; Charles O'Shaughnessy; Michael W Ball; Mark Turco; Robert J Applegate; Paul A Gurbel; Mark G Midei; Sejal S Badre; Laura Mauri; Kweli P Thompson; LeRoy A LeNarz; Richard E Kuntz
Comparison of zotarolimus-eluting and sirolimus-eluting stents in patients with native coronary artery disease: a randomized controlled trial.
Journal of the American College of Cardiology 2006;48(12):2440-7.
2006: Paul A Gurbel; Kevin P Bliden; Udaya S Tantry
Effect of clopidogrel with and without eptifibatide on tumor necrosis factor-alpha and C-reactive protein release after elective stenting: results from the CLEAR PLATELETS 1b study.
Journal of the American College of Cardiology 2006;48(11):2186-91.
2006: Udaya S Tantry; Kevin P Bliden; Paul A Gurbel
Prasugrel.
Expert opinion on investigational drugs 2006;15(12):1627-33.
2006: Wei C Lau; Paul A Gurbel
Antiplatelet drug resistance and drug-drug interactions: Role of cytochrome P450 3A4.
Pharmaceutical research 2006;23(12):2691-708.
2006: Paul A Gurbel; Udaya S Tantry
Aspirin and clopidogrel resistance: consideration and management.
Journal of interventional cardiology 2006;19(5):439-48.
2006: Paul A Gurbel; Udaya S Tantry
Drug insight: Clopidogrel nonresponsiveness.
Nature clinical practice. Cardiovascular medicine 2006;3(7):387-95.
2006: Udaya S Tantry; Amena Etherington; Kevin P Bliden; Paul A Gurbel
Antiplatelet therapy: current strategies and future trends.
Future cardiology 2006;2(3):343-66.
2006: Paul A Gurbel; Debbie Singh
Balloon angioplasty and repeat stenting may have similar long-term outcomes for people with in-stent restenosis.
Evidence-based cardiovascular medicine 2006;10(1):47-8.
2006: Barry E Bleske; John M Nicklas; Robert L Bard; Robert D Brook; Paul A Gurbel; Kevin P Bliden; Sanjay Rajagopalan; Bertram Pitt
Neutral effect on markers of heart failure, inflammation, endothelial activation and function, and vagal tone after high-dose HMG-CoA reductase inhibition in non-diabetic patients with non-ischemic cardiomyopathy and average low-density lipoprotein level.
Journal of the American College of Cardiology 2006;47(2):338-41.
2006: Paul A Gurbel
The relationship of platelet reactivity to the occurrence of post-stenting ischemic events: emergence of a new cardiovascular risk factor.
Reviews in cardiovascular medicine 2006;7 Suppl 4():S20-8.
2006: Stephen D Wiviott; Udaya S Tantry; Paul A Gurbel
Clinical applications of antiplatelet therapy.
Reviews in cardiovascular medicine 2006;7(3):130-46; quiz 148-9.
2006: Paul A Gurbel; Wei C Lau; Kevin P Bliden; Udaya S Tantry
Clopidogrel resistance: implications for coronary stenting.
Current pharmaceutical design 2006;12(10):1261-9.
2005: Udaya S Tantry; Kevin P Bliden; Paul A Gurbel
What is the best measure of thrombotic risks--pretreatment platelet aggregation, clopidogrel responsiveness, or posttreatment platelet aggregation?
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 2005;66(4):597-8.
2005: Paul A Gurbel; Kevin P Bliden; Waiel M Samara; Jason A Yoho; Kevin Hayes; Mulugeta Fissha; Udaya S Tantry
Clopidogrel effect on platelet reactivity in patients with stent thrombosis: results of the CREST Study.
Journal of the American College of Cardiology 2005;46(10):1827-32.
2005: Paul A Gurbel; Kevin P Bliden; Kirk Guyer; Peter W Cho; Kazi A Zaman; Rolf P Kreutz; Ashwani K Bassi; Udaya S Tantry
Platelet reactivity in patients and recurrent events post-stenting: results of the PREPARE POST-STENTING Study.
Journal of the American College of Cardiology 2005;46(10):1820-6.
2005: Udaya S Tantry; Kevin P Bliden; Paul A Gurbel
Overestimation of platelet aspirin resistance detection by thrombelastograph platelet mapping and validation by conventional aggregometry using arachidonic acid stimulation.
Journal of the American College of Cardiology 2005;46(9):1705-9.
2005: Udaya S Tantry; Kevin P Bliden; Paul A Gurbel
Resistance to antiplatelet drugs: current status and future research.
Expert opinion on pharmacotherapy 2005;6(12):2027-45.
2005: Rolf P Kreutz; Kevin P Bliden; Udaya S Tantry; Paul A Gurbel
Viral respiratory tract infections increase platelet reactivity and activation: an explanation for the higher rates of myocardial infarction and stroke during viral illness.
Journal of thrombosis and haemostasis : JTH 2005;3(9):2108-9.
2005: Alan D Michelson; M Cattaneo; J W Eikelboom; Paul A Gurbel; K Kottke-Marchant; T J Kunicki; F M Pulcinelli; C Cerletti; A K Rao
Aspirin resistance: position paper of the Working Group on Aspirin Resistance.
Journal of thrombosis and haemostasis : JTH 2005;3(6):1309-11.
2005: Paul A Gurbel; Kevin P Bliden; Kevin M Hayes; Jason A Yoho; WILLIAM HERZOG; Udaya S Tantry
The relation of dosing to clopidogrel responsiveness and the incidence of high post-treatment platelet aggregation in patients undergoing coronary stenting.
Journal of the American College of Cardiology 2005;45(9):1392-6.
2005: James Hermiller; Albert E Raizner; Louis A Cannon; Paul A Gurbel; Michael A Kutcher; S Chiu Wong; Mary E Russell; Stephen G Ellis; Roxana Mehran; Gregg W Stone
Outcomes with the polymer-based paclitaxel-eluting TAXUS stent in patients with diabetes mellitus: the TAXUS-IV trial.
Journal of the American College of Cardiology 2005;45(8):1172-9.
2005: Paul A Gurbel; Kevin P Bliden; Kazi A Zaman; Jason A Yoho; Kevin M Hayes; Udaya S Tantry
Clopidogrel loading with eptifibatide to arrest the reactivity of platelets: results of the Clopidogrel Loading With Eptifibatide to Arrest the Reactivity of Platelets (CLEAR PLATELETS) study.
Circulation 2005;111(9):1153-9.
2005: Robert S Poston; Junyan Gu; James M Brown; James S Gammie; Charles S White; Jeffrey Manchio; Richard N Pierson III; Bartley P Griffith; Paul A Gurbel; Udaya Tandry; Timothy B Gilbert
Hypercoagulability affecting early vein graft patency does not exist after off-pump coronary artery bypass.
Journal of cardiothoracic and vascular anesthesia 2005;19(1):11-8.
2005: Paul A Gurbel; Kevin Hayes; Kevin P Bliden; Jason A Yoho; Udaya S Tantry
The platelet-related effects of tenecteplase versus alteplase versus reteplase.
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 2005;16(1):1-7.
2005: Waiel M Samara; Kevin P Bliden; Udaya S Tantry; Paul A Gurbel
The difference between clopidogrel responsiveness and posttreatment platelet reactivity.
Thrombosis research 2005;115(1-2):89-94.
2004: Paul A Gurbel; Kevin P Bliden; Kevin M Hayes; Udaya S Tantry
Platelet activation in myocardial ischemic syndromes.
Expert review of cardiovascular therapy 2004;2(4):535-45.
2004: Karen E Joynt; Wendy A Gattis; Vic Hasselblad; Sergey Y Fuzaylov; Victor L Serebruany; Paul A Gurbel; Laura H Gaulden; G Michael Felker; David Whellan; Christopher M O'Connor
Effect of angiotensin-converting enzyme inhibitors, beta blockers, statins, and aspirin on C-reactive protein levels in outpatients with heart failure.
The American journal of cardiology 2004;93(6):783-5.
2004: Paul A Gurbel; Waiel M Samara; Kevin P Bliden
Failure of clopidogrel to reduce platelet reactivity and activation following standard dosing in elective stenting: implications for thrombotic events and restenosis.
Platelets 2004;15(2):95-9.
2004: Wei C Lau; Paul A Gurbel; Paul B Watkins; Charlene J Neer; Amy S Hopp; David G M Carville; Kirk E Guyer; Alan R Tait; Eric R Bates
Contribution of hepatic cytochrome P450 3A4 metabolic activity to the phenomenon of clopidogrel resistance.
Circulation 2004;109(2):166-71.
2003: Paul A Gurbel; Kevin P Bliden
A new method of representing drug-induced platelet inhibition: better description of time course, response variability, non-response, and heightened activity.
Platelets 2003;14(7-8):481-3.
2003: Paul A Gurbel; Kevin P Bliden
Platelet activation after stenting with heparin-coated versus noncoated stents.
American heart journal 2003;146(4):E10.
2003: Victor L Serebruany; Alex I Malinin; Christopher M O'Connor; Paul A Gurbel
Effects of roxifiban on platelet aggregation and major receptor expression in patients with coronary artery disease for the Roxifiban Oral Compound Kinetics Evaluation Trial-I (ROCKET-I Platelet Substudy).
American heart journal 2003;146(1):91-8.
2003: Paul A Gurbel; Kevin P Bliden; Bonnie L Hiatt; Christopher M O'Connor
Clopidogrel for coronary stenting: response variability, drug resistance, and the effect of pretreatment platelet reactivity.
Circulation 2003;107(23):2908-13.
2003: Paul A Gurbel; Kevin P Bliden; B L Hiatt
The early antiplatelet effects of clopidogrel loading for coronary stenting and the long-term stability of inhibition.
Journal of thrombosis and haemostasis : JTH 2003;1(6):1319-21.
2003: Paul A Gurbel; K P Bliden
Interpretation of platelet inhibition by clopidogrel and the effect of non-responders.
Journal of thrombosis and haemostasis : JTH 2003;1(6):1318-9.
2003: Paul A Gurbel; Kevin P Bliden
Durability of platelet inhibition by clopidogrel.
The American journal of cardiology 2003;91(9):1123-5.
2003: Victor L Serebruany; Alex I Malinin; Kevin P Callahan; Azan Binbrek; Frans Van de Werf; John H Alexander; Christopher B Granger; Paul A Gurbel
Effect of tenecteplase versus alteplase on platelets during the first 3 hours of treatment for acute myocardial infarction: the Assessment of the Safety and Efficacy of a New Thrombolytic Agent (ASSENT-2) platelet substudy.
American heart journal 2003;145(4):636-42.
2003: Waiel M Samara; Paul A Gurbel
The role of platelet receptors and adhesion molecules in coronary artery disease.
Coronary artery disease 2003;14(1):65-79.
2003: Paul A Gurbel; Charles C Cummings; Christopher R Bell; Amanda B Alford; Andrew F Meister; Victor L Serebruany
Onset and extent of platelet inhibition by clopidogrel loading in patients undergoing elective coronary stenting: the Plavix Reduction Of New Thrombus Occurrence (PRONTO) trial.
American heart journal 2003;145(2):239-47.
2003: Paul A Gurbel; Kevin P Bliden
The stratification of platelet reactivity and activation in patients with stable coronary artery disease on aspirin therapy.
Thrombosis research 2003;112(1-2):9-12.
2002: Paul A Gurbel; Brian Galbut; Kevin P Bliden; Raymond D Bahr; Matthew T Roe; Victor L Serebruany; W Brian Gibler; Robert H Christenson; Erik Ohman
Effect of eptifibatide for acute coronary syndromes: rapid versus late administration--therapeutic yield on platelets (The EARLY Platelet Substudy).
Journal of thrombosis and thrombolysis 2002;14(3):213-9.
2002: Paul A Gurbel; Bruce Austin; Peter W Cho; Alejandro J Sequeira
Correction of a saphenous vein graft to coronary vein anastamosis by selective retrograde coil-induced occlusion to arterialize the native vein.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 2002;57(4):541-4.
2002: David P Faxon; Raymond J Gibbons; Nicolas A F Chronos; Paul A Gurbel; Florence Sheehan
The effect of blockade of the CD11/CD18 integrin receptor on infarct size in patients with acute myocardial infarction treated with direct angioplasty: the results of the HALT-MI study.
Journal of the American College of Cardiology 2002;40(7):1199-204.
2002: Paul A Gurbel; Kevin P Callahan; Alex I Malinin; Victor L Serebruany; Jeremy Gillis
Could stent design affect platelet activation? Results of the Platelet Activation in STenting (PAST) Study.
The Journal of invasive cardiology 2002;14(10):584-9.
2002: Victor L Serebruany; M McKenzie; Andrew F Meister; Sergey Y Fuzaylov; Paul A Gurbel; Dan Atar; Wendy A Gattis; C O'Connor
Whole blood impedance aggregometry for the assessment of platelet function in patients with congestive heart failure (EPCOT Trial).
European journal of heart failure 2002;4(4):461-7.
2002: Paul A Gurbel; Alex I Malinin; Kevin P Callahan; Victor L Serebruany; Christopher M O'Connor
Effect of loading with clopidogrel at the time of coronary stenting on platelet aggregation and glycoprotein IIb/IIIa expression and platelet-leukocyte aggregate formation.
The American journal of cardiology 2002;90(3):312-5.
2002: Raymond D Bahr; Paul A Gurbel; Alex I Malinin; Charlyn Wentz; Robert H Christenson; Matthew T Roe; W Brian Gibler; Michael M Kitt; Erik Ohman; Victor L Serebruany
Relation of platelet activation and myocardial ischemia biomarkers dependent on type of chest pain (abrupt onset versus intermittent) in patients with angina pectoris or non-Q-wave acute myocardial infarction.
The American journal of cardiology 2002;90(3):310-2.
2002: Paul A Gurbel; Wendy A Gattis; Sergey F Fuzaylov; Laura H Gaulden; Vic Hasselblad; Victor L Serebruany; Christopher M O'Connor
Evaluation of platelets in heart failure: is platelet activity related to etiology, functional class, or clinical outcomes?
American heart journal 2002;143(6):1068-75.
2002: Paul A Gurbel; Victor L Serebruany
Adhesion molecules, platelet activation, and cardiovascular risk.
American heart journal 2002;143(2):196-8.
2002: Victor L Serebruany; Marcus E McKenzie; Andrew F Meister; Sergey Y Fuzaylov; Paul A Gurbel; Dan Atar; Wendy A Gattis; Christopher M O'Connor
Failure of platelet parameters and biomarkers to correlate platelet function to severity and etiology of heart failure in patients enrolled in the EPCOT trial. With special reference to the Hemodyne hemostatic analyzer. Whole Blood Impedance Aggregometry for the Assessment of Platelet Function in Patients with Congestive Heart Failure.
Pathophysiology of haemostasis and thrombosis 2002;32(1):8-15.
2001: Victor L Serebruany; Alex I Malinin; Kevin P Callahan; Paul A Gurbel; Steven R Steinhubl
Statins do not affect platelet inhibition with clopidogrel during coronary stenting.
Atherosclerosis 2001;159(1):239-41.
2001: Victor L Serebruany; C C Cummings; Alex I Malinin; Steven R Steinhubl; Paul A Gurbel
Uniform platelet activation exists before coronary stent implantation despite aspirin therapy.
American heart journal 2001;142(4):611-6.
2001: Victor L Serebruany; Christopher M O'Connor; Paul A Gurbel
Effect of selective serotonin reuptake inhibitors on platelets in patients with coronary artery disease.
The American journal of cardiology 2001;87(12):1398-400.
2001: Victor L Serebruany; Paul A Gurbel; Christopher M O'Connor
Platelet inhibition by sertraline and N-desmethylsertraline: a possible missing link between depression, coronary events, and mortality benefits of selective serotonin reuptake inhibitors.
Pharmacological research : the official journal of the Italian Pharmacological Society 2001;43(5):453-62.
2001: Victor L Serebruany; D J Levine; GV Nair; Andrew F Meister; Paul A Gurbel
Usefulness of combining necrosis and platelet markers in triaging patients presenting with chest pain to the emergency department.
Journal of thrombosis and thrombolysis 2001;11(2):155-62.
2001: Victor L Serebruany; A B Alford; Andrew F Meister; Sergey Y Fuzaylov; Wendy A Gattis; Paul A Gurbel; Christopher M O'Connor
Clinical utility of the platelet function analyzer (PFA-100) for the assessment of the platelet status in patients with congestive heart failure (EPCOT trial).
Thrombosis research 2001;101(6):427-33.
2001: Paul A Gurbel; C M O'Connor; M R Dalesandro; Victor L Serebruany
Relation of soluble and platelet P-selectin to early outcome in patients with acute myocardial infarction after thrombolytic therapy.
The American journal of cardiology 2001;87(6):774-7, A7.
2001: C C Cummings; Marcus E McKenzie; Eric D Horowitz; Benjamin R Oshrine; Kevin P Callahan; Paul A Gurbel; Victor L Serebruany
Platelet function and total length of intracoronary stents: is there a correlation?
Thrombosis research 2001;101(2):105-7.
2001: M E McKenzie; Paul A Gurbel
The potential of monoclonal antibodies to reduce reperfusion injury in myocardial infarction.
BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy 2001;15(6):395-404.
2001: Kevin P Callahan; Alex I Malinin; Paul A Gurbel; J H Alexander; C B Granger; Victor L Serebruany
Platelet function and fibrinolytic agents: two sides of a coin?
Cardiology 2001;95(2):55-60.
2000: Paul A Gurbel; Victor L Serebruany
Oral platelet IIb/IIIa inhibitors: from attractive theory to clinical failures.
Journal of thrombosis and thrombolysis 2000;10(3):217-20.
2000: H B Semaan; Paul A Gurbel; J L Anderson; J B Muhlestein; john carlquist; B D Horne; Victor L Serebruany
The effect of chronic azithromycin therapy on soluble endothelium-derived adhesion molecules in patients with coronary artery disease.
Journal of cardiovascular pharmacology 2000;36(4):533-7.
2000: Christopher M O'Connor; Paul A Gurbel; Victor L Serebruany
Depression and ischemic heart disease.
American heart journal 2000;140(4 Suppl):63-9.
2000: Victor L Serebruany; Dan Atar; SR Murugesan; Scott D Jerome; H Semaan; Paul A Gurbel
Effect of coronary thrombolysis on the plasma concentration of osteonectin (SPARC, BM40) in patients with acute myocardial infarction.
Journal of thrombosis and thrombolysis 2000;10(2):197-202.
2000: A Pothula; Victor L Serebruany; Paul A Gurbel; Marcus E McKenzie; Dan Atar
Pathophysiology and therapeutic modification of thrombin generation in patients with coronary artery disease.
European journal of pharmacology 2000;402(1-2):1-10.
2000: CJ Davis; Paul A Gurbel; Wendy A Gattis; Sergey Y Fuzaylov; GV Nair; Christopher M O'Connor; Victor L Serebruany
Hemostatic abnormalities in patients with congestive heart failure: diagnostic significance and clinical challenge.
International journal of cardiology 2000;75(1):15-21.
2000: Paul A Gurbel; DJ Kereiakes; Victor L Serebruany
Soluble P-selectin is not a surrogate marker for platelet P-selectin: evidence from a multicenter chest pain study group.
Journal of thrombosis and thrombolysis 2000;10(1):15-22.
2000: Paul A Gurbel; M E McKenzie; Victor L Serebruany
Initial platelet activity may predict efficacy after chronic oral glycoprotein IIb/IIIa blockade: should we still consider uniform treatment regimens?
Thrombosis research 2000;99(1):105-7.
2000: Victor L Serebruany; D R Lowry; S Y Fuzailov; D J Levine; C M O'Connor; Paul A Gurbel
Moderate alcohol consumption is associated with decreased platelet activity in patients presenting with acute myocardial infarction.
Journal of thrombosis and thrombolysis 2000;9(3):229-34.
2000: Victor L Serebruany; M E McKenzie; D J Levin; Paul A Gurbel
Monitoring platelet inhibition during chronic oral platelet glycoprotein IIb/IIIa blockade: are we missing something?
Thrombosis and haemostasis 2000;83(2):356-7.
2000: Paul A Gurbel; DJ Kereiakes; MR Dalesandro; Raymond D Bahr; Christopher M O'Connor; Victor L Serebruany
Role of soluble and platelet-bound P-selectin in discriminating cardiac from noncardiac chest pain at presentation in the emergency department.
American heart journal 2000;139(2 Pt 1):320-8.
2000: GV Nair; Paul A Gurbel; Sergey Y Fuzaylov; CJ Davis; Erik Ohman; Raymond D Bahr; R H Christensen; Victor L Serebruany
Combining necrosis and platelet markers for perfecting myocardial infarction rule out: how close are we?
Cardiology 2000;93(1-2):50-5.
2000: H B Semaan; Paul A Gurbel; J L Anderson; J B Muhlestein; john carlquist; B D Horne; Victor L Serebruany
Soluble VCAM-1 and E-selectin, but not ICAM-1 discriminate endothelial injury in patients with documented coronary artery disease.
Cardiology 2000;93(1-2):7-10.
2000: Paul A Gurbel; DJ Kereiakes; Dan Atar; Victor L Serebruany
Baseline platelet aggregation and major receptor expression predict subsequent activity following thrombolysis for acute myocardial infarction.
Scandinavian cardiovascular journal : SCJ 2000;34(1):53-8.
1999: Victor L Serebruany; Vladimir V Yurovsky; Paul A Gurbel
Mild myocardial stunning affects platelet aggregation and certain hemostatic factors in swine.
Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis 1999;5(4):236-42.
1999: Victor L Serebruany; DJ Kereiakes; MR Dalesandro; Paul A Gurbel
The flow cytometer model markedly affects measurement of ex vivo whole blood platelet-bound P-selectin expression in patients with chest pain: are we comparing apples with oranges.
Thrombosis research 1999;96(1):51-6.
1999: SR Murugesan; Paul A Gurbel; Victor L Serebruany
Storing paraformaldehyde-fixed whole blood patient samples after chronic platelet glycoprotein IIb/IIIa blockade: core laboratory considerations.
Thrombosis research 1999;95(4):201-3.
1999: Victor L Serebruany; SR Murugesan; A Pothula; Dan Atar; DR Lowry; Christopher M O'Connor; Paul A Gurbel
Increased soluble platelet/endothelial cellular adhesion molecule-1 and osteonectin levels in patients with severe congestive heart failure. Independence of disease etiology, and antecedent aspirin therapy.
European journal of heart failure 1999;1(3):243-9.
1999: GV Nair; Paul A Gurbel; Christopher M O'Connor; Wendy A Gattis; S R Murugesan; Victor L Serebruany
Depression, coronary events, platelet inhibition, and serotonin reuptake inhibitors.
The American journal of cardiology 1999;84(3):321-3, A8.
1999: Paul A Gurbel; Christopher M O'Connor; C C Cummings; Victor L Serebruany
Clopidogrel: the future choice for preventing platelet activation during coronary stenting?
Pharmacological research : the official journal of the Italian Pharmacological Society 1999;40(2):107-11.
1999: Paul A Gurbel; SR Murugesan; DR Lowry; Victor L Serebruany
Plasma thromboxane and prostacyclin are linear related and increased in patients presenting with acute myocardial infarction.
Prostaglandins, leukotrienes, and essential fatty acids 1999;61(1):7-11.
1999: Christopher M O'Connor; Paul A Gurbel; Victor L Serebruany
Usefulness of soluble and surface-bound P-selectin in detecting heightened platelet activity in patients with congestive heart failure.
The American journal of cardiology 1999;83(9):1345-9.
1999: Victor L Serebruany; Paul A Gurbel
The relations of major platelet receptor expression during myocardial infarction. Monitoring efficacy of GPIIb/IIIa inhibitors by measuring P-selectin?
Thrombosis and haemostasis 1999;81(2):314-6.
1999: Victor L Serebruany; Paul A Gurbel
Assessment of platelet activity by measuring platelet-derived substances in plasma from patients with acute myocardial infarction: surprising lessons from the GUSTO-III Platelet Study.
Thrombosis research 1999;93(3):149-50.
1999: M E McKenzie; Paul A Gurbel; D J Levine; Victor L Serebruany
Clinical utility of available methods for determining platelet function.
Cardiology 1999;92(4):240-7.
1999: Marcus E McKenzie; A Pothula; Paul A Gurbel; Sergey Y Fuzaylov; Christopher M O'Connor; Wendy A Gattis; Victor L Serebruany
Failure of thrombin generation markers to triage patients presenting with chest pain.
Cardiology 1999;92(1):53-8.
1999: Victor L Serebruany; Vladimir V Yurovsky; Paul A Gurbel
Effects of a novel Mac-1 inhibitor, NPC 15669, on hemostatic parameters during preconditioned myocardial infarction.
Life sciences 1999;65(14):1503-13.
1999: Victor L Serebruany; SR Murugesan; A Pothula; H Semaan; Paul A Gurbel
Soluble PECAM-1, but not P-selectin, nor osteonectin identify acute myocardial infarction in patients presenting with chest pain.
Cardiology 1999;91(1):50-5.
1999: Victor L Serebruany; Paul A Gurbel
Effect of thrombolytic therapy on platelet expression and plasma concentration of PECAM-1 (CD31) in patients with acute myocardial infarction.
Arteriosclerosis, thrombosis, and vascular biology 1999;19(1):153-8.
1998: Paul A Gurbel; MR Dalesandro; Victor L Serebruany
Reteplase but not alteplase affects early soluble PECAM-1 and P-selectin release in patients with acute myocardial infarction.
Thrombosis and haemostasis 1998;80(4):725.
1998: Victor L Serebruany; Paul A Gurbel; SR Murugesan; DR Lowry; Ekkehard Sturm; SI Svetlov
Depressed plasma platelet-activating factor acetylhydrolase in patients presenting with acute myocardial infarction.
Cardiology 1998;90(2):127-30.
1998: Victor L Serebruany; ML Schlossberg; LR Edenbaum; WILLIAM HERZOG; Paul A Gurbel
Serial changes of soluble endothelin-1 levels during myocardial ischaemia-reperfusion. Effects of magnesium, diltiazem and a novel MAC-1 inhibitor.
Pharmacological research : the official journal of the Italian Pharmacological Society 1998;38(3):165-72.
1998: Victor L Serebruany; Paul A Gurbel; AR Shustov; Erik Ohman; Eric J Topol
Heterogeneity of platelet aggregation and major surface receptor expression in patients with acute myocardial infarction.
American heart journal 1998;136(3):398-405.
1998: Victor L Serebruany; Raymond D Bahr; Christopher M O'Connor; D R Lowry; Paul A Gurbel
Antecedent aspirin therapy inhibits baseline platelet activity in patients presenting with acute myocardial infarction. The GUSTO-III Platelet Substudy.
Cardiology 1998;90(1):37-42.
1998: Victor L Serebruany; D Atar; MR Dalesandro; Christopher M O'Connor; Paul A Gurbel
Changes in hemostasis after parenteral magnesium in myocardial ischemia-reperfusion: from animal studies to clinical trials.
Magnesium research : official organ of the International Society for the Development of Research on Magnesium 1998;11(2):133-40.
1998: Paul A Gurbel; Victor L Serebruany; AR Shustov; Raymond D Bahr; C Carpo; Erik Ohman; Eric J Topol
Effects of reteplase and alteplase on platelet aggregation and major receptor expression during the first 24 hours of acute myocardial infarction treatment. GUSTO-III Investigators. Global Use of Strategies to Open Occluded Coronary Arteries.
Journal of the American College of Cardiology 1998;31(7):1466-73.
1998: Victor L Serebruany; S R Solomon; WILLIAM HERZOG; Paul A Gurbel
Plasma fibronectin during myocardial ischemia-reperfusion: effects of magnesium, diltiazem, and a novel Mac-1 inhibitor.
American journal of hematology 1998;57(4):309-14.
1998: Paul A Gurbel; Victor L Serebruany
Soluble vascular cell adhesion molecule-1 and E-selectin in patients with acute myocardial infarction treated with thrombolytic agents.
The American journal of cardiology 1998;81(6):772-5.
1998: Paul A Gurbel; Victor L Serebruany; AR Shustov; MR Dalesandro; C I Gumbs; L B Grablutz; Raymond D Bahr; Erik Ohman; Eric J Topol
Increased baseline levels of platelet P-selectin, and platelet-endothelial cell adhesion molecule-1 in patients with acute myocardial infarction as predictors of unsuccessful thrombolysis.
Coronary artery disease 1998;9(7):451-6.
1998: Victor L Serebruany; Paul A Gurbel; AR Shustov; MR Dalesandro; C I Gumbs; L B Grabletz; Raymond D Bahr; Erik Ohman; Eric J Topol
Depressed platelet status in an elderly patient with hemorrhagic stroke after thrombolysis for acute myocardial infarction. GUSTO-III Investigators.
Stroke; a journal of cerebral circulation 1998;29(1):235-8.
1997: Paul A Gurbel; Victor L Serebruany
Myths and realities of P-selectin plasma levels in patients with acute myocardial infarction.
Thrombosis research 1997;88(3):343-4.
1997: Victor L Serebruany; ML Schlossberg; LR Edenbaum; WILLIAM HERZOG; Paul A Gurbel
Effects of intracoronary diltiazem on certain hemostatic parameters during acute myocardial infarction in swine.
International journal of cardiology 1997;61(1):21-9.
1997: Victor L Serebruany; WILLIAM HERZOG; ML Schlossberg; Paul A Gurbel
Bolus magnesium infusion in humans is associated with predominantly unfavourable changes in platelet aggregation and certain haemostatic factors.
Pharmacological research : the official journal of the Italian Pharmacological Society 1997;36(1):17-22.
1997: Victor L Serebruany; WILLIAM HERZOG; Paul A Gurbel
Serial changes of the plasma prostanoids during myocardial ischemia-reperfusion in swine. Effects of magnesium, diltiazem, and a novel Mac-1 inhibitor.
Prostaglandins, leukotrienes, and essential fatty acids 1997;56(2):135-42.
1997: Paul A Gurbel; R D Anderson; H O Peels; Ad J van Boven; P den Heijer
Coronary artery angioplasty with a helical autoperfusion balloon catheter.
Catheterization and cardiovascular diagnosis 1997;40(2):179-85.
1997: Victor L Serebruany; Paul A Gurbel; J V Ordoñez; WILLIAM HERZOG; M Rohde; S A Mortensen; K Folkers
Could coenzyme Q10 affect hemostasis by inhibiting platelet vitronectin (CD51/CD61) receptor?
Molecular aspects of medicine 1997;18 Suppl():S189-94.
1997: Victor L Serebruany; J V Ordonez; WILLIAM HERZOG; M Rohde; S A Mortensen; K Folkers; Paul A Gurbel
Dietary coenzyme Q10 supplementation alters platelet size and inhibits human vitronectin (CD51/CD61) receptor expression.
Journal of cardiovascular pharmacology 1997;29(1):16-22.
1997: Paul A Gurbel; R D Anderson
New concept in coronary angioplasty: dilatation with a helical balloon that allows simultaneous autoperfusion.
Catheterization and cardiovascular diagnosis 1997;40(1):109-16.
1997: Paul A Gurbel; Frank J Criado; E A Curnutte; P Patten; J Secada-Lovio
Percutaneous revascularization of an extensively diseased saphenous vein bypass graft with a saphenous vein-covered Palmaz stent.
Catheterization and cardiovascular diagnosis 1997;40(1):75-8.
1996: Victor L Serebruany; WILLIAM HERZOG; ML Schlossberg; L R Edenbaum; Paul A Gurbel
Hemostatic changes after early versus late intracoronary magnesium during acute myocardial infarction in swine.
Journal of cardiovascular pharmacology 1996;28(6):817-23.
1996: Victor L Serebruany; WILLIAM HERZOG; L R Edenbaum; AR Shustov; Paul A Gurbel
Changes in the haemostatic profile during magnesium deficiency in swine.
Magnesium research : official organ of the International Society for the Development of Research on Magnesium 1996;9(3):155-63.
1996: Victor L Serebruany; ML Schlossberg; L R Edenbaum; WILLIAM HERZOG; Paul A Gurbel
Intracoronary magnesium and diltiazem affect to a similar extent certain hemostatic factors during acute myocardial infarction in swine.
Pharmacology 1996;53(4):224-33.
1996: Victor L Serebruany; WILLIAM HERZOG; Paul A Gurbel
Serial changes of natural antithrombotics during myocardial ischemia-reperfusion in swine. Effects of magnesium, diltiazem, and a novel Mac-1 inhibitor.
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 1996;7(6):632-40.
1996: Victor L Serebruany; S R Solomon; L R Edenbaum; WILLIAM HERZOG; Paul A Gurbel
Mac-1 inhibitor affects certain hemostatic parameters during myocardial stunning in swine.
Pharmacology 1996;53(2):87-97.
1996: Paul A Gurbel; Victor L Serebruany; S F Komiathy; M E Collins; G D Bittar; ML Schlossberg; WJ Mergner
Pretreatment with an inhibitor of mac-1 alters regional and systemic platelet function during ischemia-reperfusion in swine.
Pharmacology 1996;53(2):79-86.
1996: Victor L Serebruany; WILLIAM HERZOG; Sergei Atamas; Paul A Gurbel; M Rohde; S A Mortensen; K Folkers
Hemostatic changes after dietary coenzyme Q10 supplementation in swine.
Journal of cardiovascular pharmacology 1996;28(2):175-81.
1996: R D Anderson; Paul A Gurbel
The effect of intra-aortic balloon counterpulsation on coronary blood flow velocity distal to coronary artery stenoses.
Cardiology 1996;87(4):306-12.
1996: Paul A Gurbel; F I Navetta; Eric R Bates; David W Muller; Alan N Tenaglia; M J Miller; B Muhlstein; J B Hermiller; Charles J Davidson; FV Aguirre; G J Beauman; Lisa G Berdan; J D Leimberger; E G Bovill; Robert H Christenson; Erik Ohman
Lesion-directed administration of alteplase with intracoronary heparin in patients with unstable angina and coronary thrombus undergoing angioplasty.
Catheterization and cardiovascular diagnosis 1996;37(4):382-91.
1995: Paul A Gurbel
"Functional characteristics of a new perfusion balloon: comparison with the Flowtrack 40 in a closed chest swine".
Catheterization and cardiovascular diagnosis 1995;36(4):377-8.
1995: Paul A Gurbel; C M O'Connor
Zofenopril after anterior myocardial infarction.
The New England journal of medicine 1995;332(25):1715.
1995: C X Pimentel; S W Schreiter; Paul A Gurbel
The use of the Tracker catheter as a guidewire support device in angioplasty of angulated and tortuous circumflex coronary arteries.
The Journal of invasive cardiology 1995;7(3):66-71.
1995: Roberto M Benitez; Paul A Gurbel; H Chong; M C Rajasingh
Penetrating atherosclerotic ulcer of the aortic arch resulting in extensive and fatal dissection.
American heart journal 1995;129(4):821-3.
1994: Victor F Tapson; Paul A Gurbel; L A Witty; K S Pieper; Richard S Stack
Pharmacomechanical thrombolysis of experimental pulmonary emboli. Rapid low-dose intraembolic therapy.
Chest 1994;106(5):1558-62.
1994: Paul A Gurbel; R D Anderson; C S MacCord; H Scott; Victor L Serebruany; WILLIAM HERZOG
Accelerated intravenous dosing of recombinant tissue-type plasminogen activator causes rapid but unstable reperfusion in a canine model of acute myocardial infarction.
Coronary artery disease 1994;5(11):929-36.
1994: Erik Ohman; B S George; C J White; M J Kern; Paul A Gurbel; R J Freedman; Conor F Lundergan; J R Hartmann; JD Talley; M J Frey
Use of aortic counterpulsation to improve sustained coronary artery patency during acute myocardial infarction. Results of a randomized trial. The Randomized IABP Study Group.
Circulation 1994;90(2):792-9.
1994: Paul A Gurbel; R D Anderson; C S MacCord; H Scott; S F Komjathy; J Poulton; J Lawrence Stafford; J Godard
Arterial diastolic pressure augmentation by intra-aortic balloon counterpulsation enhances the onset of coronary artery reperfusion by thrombolytic therapy.
Circulation 1994;89(1):361-5.
1994: Paul A Gurbel; C S MacCord; R D Anderson; H Scott; D Atar; WJ Mergner; WILLIAM HERZOG
A canine model of acute coronary artery thrombosis for the evaluation of reperfusion strategies.
Cardiology 1994;84(1):1-8.
1993: WILLIAM HERZOG; D Atar; Paul A Gurbel; Robert A Vogel; ML Schlossberg; Victor L Serebruany
Effect of magnesium sulphate infusion on ex vivo platelet aggregation in swine.
Magnesium research : official organ of the International Society for the Development of Research on Magnesium 1993;6(4):349-53.
1991: Victor F Tapson; Charles J Davidson; Paul A Gurbel; K H Sheikh; Katherine B Kisslo; Richard S Stack
Rapid and accurate diagnosis of pulmonary emboli in a canine model using intravascular ultrasound imaging.
Chest 1991;100(5):1410-3.
1990: Paul A Gurbel; Charles J Davidson; Erik Ohman; J E Smith; Richard S Stack
Selective infusion of thrombolytic therapy in the acute myocardial infarct-related coronary artery as an alternative to rescue percutaneous transluminal coronary angioplasty.
The American journal of cardiology 1990;66(12):1021-3.
1990: J L Hurwitz; Ronald J Kanter; Paul A Gurbel; RA Greenfield; J H Kasell; Charles J Davidson
AV blockade via selective AV nodal artery injection in a patient.
American heart journal 1990;120(4):986-8.
1988: F I Navetta; M J Barber; Paul A Gurbel; R W Moreadith; R Bernstein; Mark A Hlatky; R E Coleman; Thomas M Bashore
Myocardial ischemia in constrictive pericarditis.
American heart journal 1988;116(4):1107-11.
1986: R H Haber; E Z Oddone; Paul A Gurbel; W W Stead
Acute pulmonary decompensation due to amphotericin B in the absence of granulocyte transfusions.
The New England journal of medicine 1986;315(13):836.