John Gurdon

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Biddle Adrian; Simeoni Ilenia; Gurdon J B
Xenopus oocytes reactivate muscle gene transcription in transplanted somatic nuclei independently of myogenic factors.
Ng Ray K; Gurdon John B
Epigenetic inheritance of cell differentiation status.
Ng Ray Kit; Gurdon J B
Epigenetic memory of an active gene state depends on histone H3.3 incorporation into chromatin in the absence of transcription.

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All Publications

2009: Biddle Adrian; Simeoni Ilenia; Gurdon J B
Xenopus oocytes reactivate muscle gene transcription in transplanted somatic nuclei independently of myogenic factors.
Development (Cambridge, England) 2009;136(16):2695-703.
2008: Ng Ray K; Gurdon John B
Epigenetic inheritance of cell differentiation status.
Cell cycle (Georgetown, Tex.) 2008;7(9):1173-7.
2008: Ng Ray Kit; Gurdon J B
Epigenetic memory of an active gene state depends on histone H3.3 incorporation into chromatin in the absence of transcription.
Nature cell biology 2008;10(1):102-9.
2007: Koziol Magdalena J; Garrett Nigel; Gurdon J B
Tpt1 activates transcription of oct4 and nanog in transplanted somatic nuclei.
Current biology : CB 2007;17(9):801-7.
2006: Kinoshita T; Jullien J; Gurdon J B
Two-dimensional morphogen gradient in Xenopus: boundary formation and real-time transduction response.
Developmental dynamics : an official publication of the American Association of Anatomists 2006;235(12):3189-98.
2006: Gurdon John B
Nuclear transplantation in Xenopus.
Methods in molecular biology (Clifton, N.J.) 2006;325():1-9.
2006: Gurdon J B
From nuclear transfer to nuclear reprogramming: the reversal of cell differentiation.
Annual review of cell and developmental biology 2006;22():1-22.
2005: Jullien Jerome; Gurdon John
Morphogen gradient interpretation by a regulated trafficking step during ligand-receptor transduction.
Genes & development 2005;19(22):2682-94.
2005: Ng Ray K; Gurdon J B
Maintenance of epigenetic memory in cloned embryos.
Cell cycle (Georgetown, Tex.) 2005;4(6):760-3.
2005: Simonsson Stina; Gurdon J B
Changing cell fate by nuclear reprogramming.
Cell cycle (Georgetown, Tex.) 2005;4(4):513-5.
2005: Harris John; Patrizio Pasquale; Gurdon John; Strong Carson; Birnbacher Dieter; Robertson John; McLaren Anne; Holm Søren; Isasi Rosario; Edwards Robert; Lockwood Gillian; White Gladys; Galton David; McMahan Jeff
Discussion (day 1 session 3): Moral philosophy of human reproductive cloning.
Reproductive biomedicine online 2005;10 Suppl 1():56-9.
2005: Gurdon J B
Reproductive cloning: past, present and future.
Reproductive biomedicine online 2005;10 Suppl 1():43-4.
2005: Gurdon J B
The use of Xenopus oocytes and embryos as a route towards cell replacement.
Journal of biosciences 2005;30(1):11-4.
2005: Ng Ray K; Gurdon John B
Epigenetic memory of active gene transcription is inherited through somatic cell nuclear transfer.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(6):1957-62.
2005: Gurdon J B; Byrne J A; Simonsson S
Nuclear reprogramming by xenopus oocytes.
Novartis Foundation symposium 2005;265():129-36; discussion 136-41, 204-11.
2004: Simonsson Stina; Gurdon John
DNA demethylation is necessary for the epigenetic reprogramming of somatic cell nuclei.
Nature cell biology 2004;6(10):984-90.
2004: Gurdon J B; Byrne J A
The first half-century of nuclear transplantation.
Bioscience reports 2004;24(4-5):545-57.
2003: Gurdon John
John Gurdon.
Current biology : CB 2003;13(19):R759-60.
2003: Gurdon J B; Byrne J A; Simonsson S
Nuclear reprogramming and stem cell creation.
Proceedings of the National Academy of Sciences of the United States of America 2003;100 Suppl 1():11819-22.
2003: Byrne James A; Simonsson Stina; Western Patrick S; Gurdon John B
Nuclei of adult mammalian somatic cells are directly reprogrammed to oct-4 stem cell gene expression by amphibian oocytes.
Current biology : CB 2003;13(14):1206-13.
2003: Gurdon J B; Byrne J A
The first half-century of nuclear transplantation.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(14):8048-52.
2003: Gurdon John B
Nuclear reprogramming and the redirection of cell fate in Xenopus.
Oncology research 2003;13(6-10):301.
2002: Standley Henrietta J; Gurdon John B
Uncommitted Xenopus blastula cells can be directed to uniform muscle gene expression by gradient interpretation and a community effect.
The International journal of developmental biology 2002;46(8):993-8.
2002: Gurdon J B
Perspective on the Xenopus field.
Developmental dynamics : an official publication of the American Association of Anatomists 2002;225(4):379.
2002: Grimm Oliver H; Gurdon J B
Nuclear exclusion of Smad2 is a mechanism leading to loss of competence.
Nature cell biology 2002;4(7):519-22.
2002: Standley Henrietta J; Zorn Aaron M; Gurdon John B
A dynamic requirement for community interactions during Xenopus myogenesis.
The International journal of developmental biology 2002;46(3):279-83.
2002: Bourillot P-Y; Garrett N; Gurdon J B
A changing morphogen gradient is interpreted by continuous transduction flow.
Development (Cambridge, England) 2002;129(9):2167-80.
2002: Byrne J A; Simonsson S; Gurdon J B
From intestine to muscle: nuclear reprogramming through defective cloned embryos.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(9):6059-63.
2002: Byrne James A; Gurdon John B
Commentary on human cloning.
Differentiation; research in biological diversity 2002;69(4-5):154-7.
2001: Gurdon J B; Bourillot P Y
Morphogen gradient interpretation.
Nature 2001;413(6858):797-803.
2001: Shimizu K; Bourillot P Y; Nielsen S J; Zorn A M; Gurdon J B
Swift is a novel BRCT domain coactivator of Smad2 in transforming growth factor beta signaling.
Molecular and cellular biology 2001;21(12):3901-12.
2001: Butler K; Zorn A M; Gurdon J B
Nonradioactive in situ hybridization to xenopus tissue sections.
Methods (San Diego, Calif.) 2001;23(4):303-12.
2001: Standley H J; Zorn A M; Gurdon J B
eFGF and its mode of action in the community effect during Xenopus myogenesis.
Development (Cambridge, England) 2001;128(8):1347-57.
2001: McDowell N; Gurdon J B; Grainger D J
Formation of a functional morphogen gradient by a passive process in tissue from the early Xenopus embryo.
The International journal of developmental biology 2001;45(1):199-207.
2000: Ryan K; Garrett N; Bourillot P; Stennard F; Gurdon J B
The Xenopus eomesodermin promoter and its concentration-dependent response to activin.
Mechanisms of development 2000;94(1-2):133-46.
2000: Gurdon J B; Hopwood N
The introduction of Xenopus laevis into developmental biology: of empire, pregnancy testing and ribosomal genes.
The International journal of developmental biology 2000;44(1):43-50.
1999: Gurdon J B; Standley H; Dyson S; Butler K; Langon T; Ryan K; Stennard F; Shimizu K; Zorn A
Single cells can sense their position in a morphogen gradient.
Development (Cambridge, England) 1999;126(23):5309-17.
1999: Stennard F; Zorn A M; Ryan K; Garrett N; Gurdon J B
Differential expression of VegT and Antipodean protein isoforms in Xenopus.
Mechanisms of development 1999;86(1-2):87-98.
1999: McDowell N; Gurdon J B
Activin as a morphogen in Xenopus mesoderm induction.
Seminars in cell & developmental biology 1999;10(3):311-7.
1999: Gurdon J B
Genetic reprogramming following nuclear transplantation in Amphibia.
Seminars in cell & developmental biology 1999;10(3):239-43.
1999: Shimizu K; Gurdon J B
A quantitative analysis of signal transduction from activin receptor to nucleus and its relevance to morphogen gradient interpretation.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(12):6791-6.
1999: Zorn A M; Butler K; Gurdon J B
Anterior endomesoderm specification in Xenopus by Wnt/beta-catenin and TGF-beta signalling pathways.
Developmental biology 1999;209(2):282-97.
1998: Gurdon J B; Dyson S; St Johnston D
Cells' perception of position in a concentration gradient.
Cell 1998;95(2):159-62.
1998: Ryan K; Butler K; Bellefroid E; Gurdon J B
Xenopus eomesodermin is expressed in neural differentiation.
Mechanisms of development 1998;75(1-2):155-8.
1998: Mahony D; Weis F M; Massagué J; Gurdon J B
XTrR-I is a TGFbeta receptor and overexpression of truncated form of the receptor inhibits axis formation and dorsalising activity.
Mechanisms of development 1998;75(1-2):95-105.
1998: Dyson S; Gurdon J B
The interpretation of position in a morphogen gradient as revealed by occupancy of activin receptors.
Cell 1998;93(4):557-68.
1998: Crease D J; Dyson S; Gurdon J B
Cooperation between the activin and Wnt pathways in the spatial control of organizer gene expression.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(8):4398-403.
1997: Stennard F; Ryan K; Gurdon J B
Markers of vertebrate mesoderm induction.
Current opinion in genetics & development 1997;7(5):620-7.
1997: McDowell N; Zorn A M; Crease D J; Gurdon J B
Activin has direct long-range signalling activity and can form a concentration gradient by diffusion.
Current biology : CB 1997;7(9):671-81.
1997: Carnac G; Gurdon J B
The community effect in Xenopus myogenesis is promoted by dorsalizing factors.
The International journal of developmental biology 1997;41(3):521-4.
1997: Dyson S; Gurdon J B
Activin signalling has a necessary function in Xenopus early development.
Current biology : CB 1997;7(1):81-4.
1997: Gurdon J B; Ryan K; Stennard F; McDowell N; Zorn A M; Crease D J; Dyson S
Cell response to different concentrations of a morphogen: activin effects on Xenopus animal caps.
Cold Spring Harbor symposia on quantitative biology 1997;62():151-8.
1997: Gurdon J B; Lemaire P; Mohun T J
Myogenesis in Xenopus embryos.
Methods in cell biology 1997;52():53-66.
1996: Stennard F; Carnac G; Gurdon J B
The Xenopus T-box gene, Antipodean, encodes a vegetally localised maternal mRNA and can trigger mesoderm formation.
Development (Cambridge, England) 1996;122(12):4179-88.
1996: Ryan K; Garrett N; Mitchell A; Gurdon J B
Eomesodermin, a key early gene in Xenopus mesoderm differentiation.
Cell 1996;87(6):989-1000.
1996: Carnac G; Kodjabachian L; Gurdon J B; Lemaire P
The homeobox gene Siamois is a target of the Wnt dorsalisation pathway and triggers organiser activity in the absence of mesoderm.
Development (Cambridge, England) 1996;122(10):3055-65.
1996: Chan A P; Gurdon J B
Nuclear transplantation from stably transfected cultured cells of Xenopus.
The International journal of developmental biology 1996;40(2):441-51.
1996: Gurdon J B; Ryan K; Stennard F; McDowell N; Crease D; Dyson S; Zorn A; Garrett N; Mitchell A; Carnac G
Long range signalling process in embryonic development.
The International journal of developmental biology 1996;Suppl 1():57S-58S.
1995: Mahony D; Gurdon J B
A type 1 serine/threonine kinase receptor that can dorsalize mesoderm in Xenopus.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(14):6474-8.
1994: Holt C E; Lemaire P; Gurdon J B
Cadherin-mediated cell interactions are necessary for the activation of MyoD in Xenopus mesoderm.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(23):10844-8.
1994: Kato K; Gurdon J B
An inhibitory effect of Xenopus gastrula ectoderm on muscle cell differentiation and its role for dorsoventral patterning of mesoderm.
Developmental biology 1994;163(1):222-9.
1993: Gurdon J B; Lemaire P; Kato K
Community effects and related phenomena in development.
Cell 1993;75(5):831-4.
1993: Gurdon J B; Kato K; Lemaire P
The community effect, dorsalization and mesoderm induction.
Current opinion in genetics & development 1993;3(4):662-7.
1993: Kato K; Gurdon J B
Single-cell transplantation determines the time when Xenopus muscle precursor cells acquire a capacity for autonomous differentiation.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(4):1310-4.
1993: Gurdon J B; Tiller E; Roberts J; Kato K
A community effect in muscle development.
Current biology : CB 1993;3(1):1-11.
1992: Rashbass J; Taylor M V; Gurdon J B
The DNA-binding protein E12 co-operates with XMyoD in the activation of muscle-specific gene expression in Xenopus embryos.
The EMBO journal 1992;11(8):2981-90.
1992: Hopwood N D; Pluck A; Gurdon J B; Dilworth S M
Expression of XMyoD protein in early Xenopus laevis embryos.
Development (Cambridge, England) 1992;114(1):31-8.
1992: Gurdon J B; Hopwood N D; Taylor M V
Mechanisms of gene activation in early vertebrate development.
Comptes rendus de l'Académie des sciences. Série III, Sciences de la vie 1992;314(9 Suppl):51-3.
1991: Taylor M V; Gurdon J B; Hopwood N D; Towers N; Mohun T J
Xenopus embryos contain a somite-specific, MyoD-like protein that binds to a promoter site required for muscle actin expression.
Genes & development 1991;5(7):1149-60.
1991: Hopwood N D; Pluck A; Gurdon J B
Xenopus Myf-5 marks early muscle cells and can activate muscle genes ectopically in early embryos.
Development (Cambridge, England) 1991;111(2):551-60.
1991: Gurdon J B
Nuclear transplantation in Xenopus.
Methods in cell biology 1991;36():299-309.
1991: Hopwood N D; Gurdon J B
Gene activation in the amphibian mesoderm.
Development (Cambridge, England). Supplement 1991;1():95-104.
1990: Hopwood N D; Gurdon J B
Activation of muscle genes without myogenesis by ectopic expression of MyoD in frog embryo cells.
Nature 1990;347(6289):197-200.
1990: Sharpe C R; Gurdon J B
The induction of anterior and posterior neural genes in Xenopus laevis.
Development (Cambridge, England) 1990;109(4):765-74.
1989: Sharpe C R; Pluck A; Gurdon J B
XIF3, a Xenopus peripherin gene, requires an inductive signal for enhanced expression in anterior neural tissue.
Development (Cambridge, England) 1989;107(4):701-14.
1989: Hopwood N D; Pluck A; Gurdon J B
A Xenopus mRNA related to Drosophila twist is expressed in response to induction in the mesoderm and the neural crest.
Cell 1989;59(5):893-903.
1989: Hopwood N D; Pluck A; Gurdon J B
MyoD expression in the forming somites is an early response to mesoderm induction in Xenopus embryos.
The EMBO journal 1989;8(11):3409-17.
1989: Gurdon J B
The Florey lecture, 1988. From egg to embryo: the initiation of cell differentiation in Amphibia.
Proceedings of the Royal Society of London. Series B, Containing papers of a Biological character. Royal Society (Great Britain) 1989;237(1286):11-25.
1989: Mohun T J; Taylor M V; Garrett N; Gurdon J B
The CArG promoter sequence is necessary for muscle-specific transcription of the cardiac actin gene in Xenopus embryos.
The EMBO journal 1989;8(4):1153-61.
1989: Gurdon J B; Mohun T J; Sharpe C R; Taylor M V
Embryonic induction and muscle gene activation.
Trends in genetics : TIG 1989;5(2):51-6.
1989: Gurdon J B
The localization of an inductive response.
Development (Cambridge, England) 1989;105(1):27-33.
1988: Gurdon J B
A community effect in animal development.
Nature 1988;336(6201):772-4.
1988: Gurdon J B
The origin of cell-type differences in early embryos.
Cell differentiation and development : the official journal of the International Society of Developmental Biologists 1988;25 Suppl():1-6.
1987: Cascio S; Gurdon J B
The initiation of new gene transcription during Xenopus gastrulation requires immediately preceding protein synthesis.
Development (Cambridge, England) 1987;100(2):297-305.
1987: Gurdon J B
Embryonic induction--molecular prospects.
Development (Cambridge, England) 1987;99(3):285-306.

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John Gurdon

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